Karl W. Broman - Publications

Affiliations: 
Statistics University of Wisconsin, Madison, Madison, WI 
Area:
Statistics, Genetics

134 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 De Simone M, Spagnuolo L, Lorè NI, Cigana C, De Fino I, Broman KW, Iraqi FA, Bragonzi A. Mapping genetic determinants of host susceptibility to Pseudomonas aeruginosa lung infection in mice. Bmc Genomics. 17: 351. PMID 27169516 DOI: 10.1186/s12864-016-2676-4  0.56
2016 Gruhn JR, Al-Asmar N, Fasnacht R, Maylor-Hagen H, Peinado V, Rubio C, Broman KW, Hunt PA, Hassold T. Correlations between Synaptic Initiation and Meiotic Recombination: A Study of Humans and Mice. American Journal of Human Genetics. 98: 102-15. PMID 26749305 DOI: 10.1016/j.ajhg.2015.11.019  0.56
2015 Kwak IY, Moore CR, Spalding EP, Broman KW. Mapping Quantitative Trait Loci Underlying Function-Valued Traits Using Functional Principal Component Analysis and Multi-trait Mapping. G3 (Bethesda, Md.). PMID 26530421 DOI: 10.1534/g3.115.024133  0.56
2015 Gray MM, Parmenter M, Hogan C, Ford I, Cuthbert RJ, Ryan PG, Broman KW, Payseur BA. Genetics of Rapid and Extreme Size Evolution in Island Mice. Genetics. PMID 26199233 DOI: 10.1534/genetics.115.177790  0.56
2015 Broman KW. R/qtlcharts: interactive graphics for quantitative trait locus mapping. Genetics. 199: 359-61. PMID 25527287 DOI: 10.1534/genetics.114.172742  0.56
2015 Whitney KD, Broman KW, Kane NC, Hovick SM, Randell RA, Rieseberg LH. Quantitative trait locus mapping identifies candidate alleles involved in adaptive introgression and range expansion in a wild sunflower. Molecular Ecology. 24: 2194-211. PMID 25522096 DOI: 10.1111/mec.13044  0.56
2014 Gatti DM, Svenson KL, Shabalin A, Wu LY, Valdar W, Simecek P, Goodwin N, Cheng R, Pomp D, Palmer A, Chesler EJ, Broman KW, Churchill GA. Quantitative trait locus mapping methods for diversity outbred mice. G3 (Bethesda, Md.). 4: 1623-33. PMID 25237114 DOI: 10.1534/g3.114.013748  0.56
2014 Florek NW, Weinfurter JT, Jegaskanda S, Brewoo JN, Powell TD, Young GR, Das SC, Hatta M, Broman KW, Hungnes O, Dudman SG, Kawaoka Y, Kent SJ, Stinchcomb DT, Osorio JE, et al. Modified vaccinia virus Ankara encoding influenza virus hemagglutinin induces heterosubtypic immunity in macaques. Journal of Virology. 88: 13418-28. PMID 25210172 DOI: 10.1128/JVI.01219-14  0.56
2014 Rowsey R, Gruhn J, Broman KW, Hunt PA, Hassold T. Examining variation in recombination levels in the human female: a test of the production-line hypothesis. American Journal of Human Genetics. 95: 108-12. PMID 24995869 DOI: 10.1016/j.ajhg.2014.06.008  0.56
2014 Street VA, Kujawa SG, Manichaikul A, Broman KW, Kallman JC, Shilling DJ, Iwata AJ, Robinson LC, Robbins CA, Li J, Liberman MC, Tempel BL. Resistance to noise-induced hearing loss in 129S6 and MOLF mice: identification of independent, overlapping, and interacting chromosomal regions. Journal of the Association For Research in Otolaryngology : Jaro. 15: 721-38. PMID 24952082 DOI: 10.1007/s10162-014-0472-x  0.56
2014 Kwak IY, Moore CR, Spalding EP, Broman KW. A simple regression-based method to map quantitative trait loci underlying function-valued phenotypes. Genetics. 197: 1409-16. PMID 24931408 DOI: 10.1534/genetics.114.166306  0.56
2014 Huang BE, Raghavan C, Mauleon R, Broman KW, Leung H. Efficient imputation of missing markers in low-coverage genotyping-by-sequencing data from multiparental crosses. Genetics. 197: 401-4. PMID 24583583 DOI: 10.1534/genetics.113.158014  0.56
2014 Baier B, Hunt P, Broman KW, Hassold T. Variation in genome-wide levels of meiotic recombination is established at the onset of prophase in mammalian males. Plos Genetics. 10: e1004125. PMID 24497841 DOI: 10.1371/journal.pgen.1004125  0.56
2013 Gruhn JR, Rubio C, Broman KW, Hunt PA, Hassold T. Cytological studies of human meiosis: sex-specific differences in recombination originate at, or prior to, establishment of double-strand breaks. Plos One. 8: e85075. PMID 24376867 DOI: 10.1371/journal.pone.0085075  0.56
2013 Bautz DJ, Broman KW, Threadgill DW. Identification of a novel polymorphism in X-linked sterol-4-alpha-carboxylate 3-dehydrogenase (Nsdhl) associated with reduced high-density lipoprotein cholesterol levels in I/LnJ mice. G3 (Bethesda, Md.). 3: 1819-25. PMID 23979938 DOI: 10.1534/g3.113.007567  0.56
2013 Moore CR, Johnson LS, Kwak IY, Livny M, Broman KW, Spalding EP. High-throughput computer vision introduces the time axis to a quantitative trait map of a plant growth response. Genetics. 195: 1077-86. PMID 23979570 DOI: 10.1534/genetics.113.153346  0.56
2013 Harris M, Burns CM, Becker EA, Braasch AT, Gostick E, Johnson RC, Broman KW, Price DA, Friedrich TC, O'Connor SL. Acute-phase CD8 T cell responses that select for escape variants are needed to control live attenuated simian immunodeficiency virus. Journal of Virology. 87: 9353-64. PMID 23785211 DOI: 10.1128/JVI.00909-13  0.56
2013 Maenner MJ, Baker MW, Broman KW, Tian J, Barnes JK, Atkins A, McPherson E, Hong J, Brilliant MH, Mailick MR. FMR1 CGG expansions: prevalence and sex ratios. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 162: 466-73. PMID 23740716 DOI: 10.1002/ajmg.b.32176  0.56
2013 Lee MH, Jones G, Amlin-Van Schaick J, DiFabio C, Whitman M, Shankavarum U, Huynh T, Kim S, Pacak K, Broman KW, Reilly KM. Modifiers of Neurofibromatosis-Associated Tumors and the Potential Role for Catecholamines and Sex Differences Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 73. DOI: 10.1016/B978-0-12-800044-1.00064-7  0.56
2012 Galvan A, Colombo F, Noci S, Pazzaglia S, Mancuso M, Manenti G, Broman KW, Saran A, Dragani TA. The Lsktm1 locus modulates lung and skin tumorigenesis in the mouse. G3 (Bethesda, Md.). 2: 1041-6. PMID 22973541 DOI: 10.1534/g3.112.003525  0.56
2012 Greene JM, Chin EN, Budde ML, Lhost JJ, Hines PJ, Burwitz BJ, Broman KW, Nelson JE, Friedrich TC, O'Connor DH. Ex vivo SIV-specific CD8 T cell responses in heterozygous animals are primarily directed against peptides presented by a single MHC haplotype. Plos One. 7: e43690. PMID 22928016 DOI: 10.1371/journal.pone.0043690  0.56
2012 Broman KW, Kim S, Sen S, Ané C, Payseur BA. Mapping quantitative trait loci onto a phylogenetic tree. Genetics. 192: 267-79. PMID 22745229 DOI: 10.1534/genetics.112.142448  0.56
2012 King EG, Merkes CM, McNeil CL, Hoofer SR, Sen S, Broman KW, Long AD, Macdonald SJ. Genetic dissection of a model complex trait using the Drosophila Synthetic Population Resource. Genome Research. 22: 1558-66. PMID 22496517 DOI: 10.1101/gr.134031.111  0.56
2012 Broman KW. Haplotype probabilities in advanced intercross populations. G3 (Bethesda, Md.). 2: 199-202. PMID 22384398 DOI: 10.1534/g3.111.001818  0.56
2012 Broman KW. Genotype probabilities at intermediate generations in the construction of recombinant inbred lines. Genetics. 190: 403-12. PMID 22345609 DOI: 10.1534/genetics.111.132647  0.56
2012 Arends D, van der Velde KJ, Prins P, Broman KW, Möller S, Jansen RC, Swertz MA. xQTL workbench: a scalable web environment for multi-level QTL analysis. Bioinformatics (Oxford, England). 28: 1042-4. PMID 22308096 DOI: 10.1093/bioinformatics/bts049  0.56
2012 Amlin-Van Schaick JC, Kim S, DiFabio C, Lee MH, Broman KW, Reilly KM. Arlm1 is a male-specific modifier of astrocytoma resistance on mouse Chr 12. Neuro-Oncology. 14: 160-74. PMID 22234937 DOI: 10.1093/neuonc/nor206  0.56
2012 Amlin-Van Schaick J, Kim S, Broman KW, Reilly KM. Scram1 is a modifier of spinal cord resistance for astrocytoma on mouse Chr 5. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 277-85. PMID 22160242 DOI: 10.1007/s00335-011-9380-0  0.56
2012 Davis RC, van Nas A, Castellani LW, Zhao Y, Zhou Z, Wen P, Yu S, Qi H, Rosales M, Schadt EE, Broman KW, Péterfy M, Lusis AJ. Systems genetics of susceptibility to obesity-induced diabetes in mice. Physiological Genomics. 44: 1-13. PMID 22010005 DOI: 10.1152/physiolgenomics.00003.2011  0.56
2011 Weinfurter JT, Brunner K, Capuano SV, Li C, Broman KW, Kawaoka Y, Friedrich TC. Cross-reactive T cells are involved in rapid clearance of 2009 pandemic H1N1 influenza virus in nonhuman primates. Plos Pathogens. 7: e1002381. PMID 22102819 DOI: 10.1371/journal.ppat.1002381  0.56
2011 Greene JM, Wiseman RW, Lank SM, Bimber BN, Karl JA, Burwitz BJ, Lhost JJ, Hawkins OE, Kunstman KJ, Broman KW, Wolinsky SM, Hildebrand WH, O'Connor DH. Differential MHC class I expression in distinct leukocyte subsets. Bmc Immunology. 12: 39. PMID 21762519 DOI: 10.1186/1471-2172-12-39  0.56
2011 Moreland AJ, Guethlein LA, Reeves RK, Broman KW, Johnson RP, Parham P, O'Connor DH, Bimber BN. Characterization of killer immunoglobulin-like receptor genetics and comprehensive genotyping by pyrosequencing in rhesus macaques. Bmc Genomics. 12: 295. PMID 21645414 DOI: 10.1186/1471-2164-12-295  0.56
2011 Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, ... ... Broman KW, et al. Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Research. 21: 1213-22. PMID 21406540 DOI: 10.1101/gr.111310.110  0.56
2011 Svetec N, Werzner A, Wilches R, Pavlidis P, Alvarez-Castro JM, Broman KW, Metzler D, Stephan W. Identification of X-linked quantitative trait loci affecting cold tolerance in Drosophila melanogaster and fine mapping by selective sweep analysis. Molecular Ecology. 20: 530-44. PMID 21199023 DOI: 10.1111/j.1365-294X.2010.04951.x  0.56
2011 Bradley KM, Breyer JP, Melville DB, Broman KW, Knapik EW, Smith JR. An SNP-based linkage map for zebrafish reveals sex determination loci G3: Genes, Genomes, Genetics. 1: 3-9. DOI: 10.1534/g3.111.000190z  0.56
2011 Gruhn JR, Broman KW, Hunt PA, Hassold TJ. The embryo/blastomere: Meiotic recombination in human oocytes Stem Cells in Reproductive Medicine: Basic Science and Therapeutic Potential. 63-75. DOI: 10.1017/CBO9781139540742.007  0.56
2010 Billings T, Sargent EE, Szatkiewicz JP, Leahy N, Kwak IY, Bektassova N, Walker M, Hassold T, Graber JH, Broman KW, Petkov PM. Patterns of recombination activity on mouse chromosome 11 revealed by high resolution mapping. Plos One. 5: e15340. PMID 21170346 DOI: 10.1371/journal.pone.0015340  0.56
2010 Murdoch B, Owen N, Shirley S, Crumb S, Broman KW, Hassold T. Multiple loci contribute to genome-wide recombination levels in male mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 21: 550-5. PMID 21113599 DOI: 10.1007/s00335-010-9303-5  0.56
2010 Arends D, Prins P, Jansen RC, Broman KW. R/qtl: high-throughput multiple QTL mapping. Bioinformatics (Oxford, England). 26: 2990-2. PMID 20966004 DOI: 10.1093/bioinformatics/btq565  0.56
2010 Bader HL, Ruhe AL, Wang LW, Wong AK, Walsh KF, Packer RA, Mitelman J, Robertson KR, O'Brien DP, Broman KW, Shelton GD, Apte SS, Neff MW. An ADAMTSL2 founder mutation causes Musladin-Lueke Syndrome, a heritable disorder of beagle dogs, featuring stiff skin and joint contractures. Plos One. 5. PMID 20862248 DOI: 10.1371/journal.pone.0012817  0.56
2010 Jurisic G, Sundberg JP, Bleich A, Leiter EH, Broman KW, Buechler G, Alley L, Vestweber D, Detmar M. Quantitative lymphatic vessel trait analysis suggests Vcam1 as candidate modifier gene of inflammatory bowel disease Genes and Immunity. 11: 219-231. PMID 20220769 DOI: 10.1038/gene.2010.4  0.56
2010 Burrage LC, Baskin-Hill AE, Sinasac DS, Singer JB, Croniger CM, Kirby A, Kulbokas EJ, Daly MJ, Lander ES, Broman KW, Nadeau JH. Genetic resistance to diet-induced obesity in chromosome substitution strains of mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 21: 115-29. PMID 20127486 DOI: 10.1007/s00335-010-9247-9  0.56
2010 Greene JM, Lhost JJ, Burwitz BJ, Budde ML, Macnair CE, Weiker MK, Gostick E, Friedrich TC, Broman KW, Price DA, O'Connor SL, O'Connor DH. Extralymphoid CD8+ T cells resident in tissue from simian immunodeficiency virus SIVmac239{Delta}nef-vaccinated macaques suppress SIVmac239 replication ex vivo. Journal of Virology. 84: 3362-72. PMID 20089651 DOI: 10.1128/JVI.02028-09  0.56
2010 Wong AK, Ruhe AL, Dumont BL, Robertson KR, Guerrero G, Shull SM, Ziegle JS, Millon LV, Broman KW, Payseur BA, Neff MW. A comprehensive linkage map of the dog genome. Genetics. 184: 595-605. PMID 19966068 DOI: 10.1534/genetics.109.106831  0.56
2010 Manichaikul A, Moon JY, Sen S, Yandell BS, Broman KW. A model selection approach for the identification of quantitative trait loci in experimental crosses, allowing epistasis (Genetics 181 (1077-1086)) Genetics. 184: 607. DOI: 10.1534/genetics.109.112912  0.56
2009 Shavit JA, Manichaikul A, Lemmerhirt HL, Broman KW, Ginsburg D. Modifiers of von Willebrand factor identified by natural variation in inbred strains of mice. Blood. 114: 5368-74. PMID 19789385 DOI: 10.1182/blood-2009-07-233213  0.56
2009 Cheng EY, Hunt PA, Naluai-Cecchini TA, Fligner CL, Fujimoto VY, Pasternack TL, Schwartz JM, Steinauer JE, Woodruff TJ, Cherry SM, Hansen TA, Vallente RU, Broman KW, Hassold TJ. Meiotic recombination in human oocytes. Plos Genetics. 5: e1000661. PMID 19763179 DOI: 10.1371/journal.pgen.1000661  0.56
2009 Dumont BL, Broman KW, Payseur BA. Variation in genomic recombination rates among heterogeneous stock mice. Genetics. 182: 1345-9. PMID 19535547 DOI: 10.1534/genetics.109.105114  0.56
2009 Cox A, Ackert-Bicknell CL, Dumont BL, Ding Y, Bell JT, Brockmann GA, Wergedal JE, Bult C, Paigen B, Flint J, Tsaih SW, Churchill GA, Broman KW. A new standard genetic map for the laboratory mouse. Genetics. 182: 1335-44. PMID 19535546 DOI: 10.1534/genetics.109.105486  0.56
2009 Venkatesan M, Broman KW, Sellers M, Rasgon JL. An initial linkage map of the West Nile Virus vector Culex tarsalis Insect Molecular Biology. 18: 453-463. PMID 19453767 DOI: 10.1111/j.1365-2583.2009.00885.x  0.56
2009 Manichaikul A, Broman KW. Binary trait mapping in experimental crosses with selective genotyping. Genetics. 182: 863-74. PMID 19416941 DOI: 10.1534/genetics.108.098913  0.56
2009 Sen S, Johannes F, Broman KW. Selective genotyping and phenotyping strategies in a complex trait context. Genetics. 181: 1613-26. PMID 19153260 DOI: 10.1534/genetics.108.094607  0.56
2009 Manichaikul A, Moon JY, Sen S, Yandell BS, Broman KW. A model selection approach for the identification of quantitative trait loci in experimental crosses, allowing epistasis. Genetics. 181: 1077-86. PMID 19104078 DOI: 10.1534/genetics.108.094565  0.56
2008 Shao H, Burrage LC, Sinasac DS, Hill AE, Ernest SR, O'Brien W, Courtland HW, Jepsen KJ, Kirby A, Kulbokas EJ, Daly MJ, Broman KW, Lander ES, Nadeau JH. Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis. Proceedings of the National Academy of Sciences of the United States of America. 105: 19910-4. PMID 19066216 DOI: 10.1073/pnas.0810388105  0.56
2008 Paigen K, Szatkiewicz JP, Sawyer K, Leahy N, Parvanov ED, Ng SH, Graber JH, Broman KW, Petkov PM. The recombinational anatomy of a mouse chromosome. Plos Genetics. 4: e1000119. PMID 18617997 DOI: 10.1371/journal.pgen.1000119  0.56
2008 Hill MM, Broman KW, Stupka E, Smith WC, Jiang D, Sidow A. The C. savignyi genetic map and its integration with the reference sequence facilitates insights into chordate genome evolution. Genome Research. 18: 1369-79. PMID 18519652 DOI: 10.1101/gr.078576.108  0.56
2008 Peirce JL, Broman KW, Lu L, Chesler EJ, Zhou G, Airey DC, Birmingham AE, Williams RW. Genome Reshuffling for Advanced Intercross Permutation (GRAIP): simulation and permutation for advanced intercross population analysis. Plos One. 3: e1977. PMID 18431467 DOI: 10.1371/journal.pone.0001977  0.56
2008 Bjornsson HT, Albert TJ, Ladd-Acosta CM, Green RD, Rongione MA, Middle CM, Irizarry RA, Broman KW, Feinberg AP. SNP-specific array-based allele-specific expression analysis. Genome Research. 18: 771-9. PMID 18369178 DOI: 10.1101/gr.073254.107  0.56
2008 Lupi I, Broman KW, Tzou SC, Gutenberg A, Martino E, Caturegli P. Novel autoantigens in autoimmune hypophysitis. Clinical Endocrinology. 69: 269-78. PMID 18194487 DOI: 10.1111/j.1365-2265.2008.03180.x  0.56
2008 Roy-Gagnon MH, Mathias RA, Fallin MD, Jee SH, Broman KW, Wilson AF. An extension of the regression of offspring on mid-parent to test for association and estimate locus-specific heritability: the revised ROMP method. Annals of Human Genetics. 72: 115-25. PMID 18042270 DOI: 10.1111/j.1469-1809.2007.00401.x  0.56
2008 Sinha D, Klise A, Sergeev Y, Hose S, Bhutto IA, Hackler L, Malpic-Llanos T, Samtani S, Grebe R, Goldberg MF, Hejtmancik JF, Nath A, Zack DJ, Fariss RN, McLeod DS, ... ... Broman KW, et al. betaA3/A1-crystallin in astroglial cells regulates retinal vascular remodeling during development. Molecular and Cellular Neurosciences. 37: 85-95. PMID 17931883 DOI: 10.1016/j.mcn.2007.08.016  0.56
2007 Petkov PM, Broman KW, Szatkiewicz JP, Paigen K. Crossover interference underlies sex differences in recombination rates. Trends in Genetics : Tig. 23: 539-42. PMID 17964681 DOI: 10.1016/j.tig.2007.08.015  0.56
2007 Peirce JL, Broman KW, Lu L, Williams RW. A simple method for combining genetic mapping data from multiple crosses and experimental designs. Plos One. 2: e1036. PMID 17940600 DOI: 10.1371/journal.pone.0001036  0.56
2007 Manichaikul A, Palmer AA, Sen S, Broman KW. Significance thresholds for quantitative trait locus mapping under selective genotyping. Genetics. 177: 1963-6. PMID 17720902 DOI: 10.1534/genetics.107.080093  0.56
2007 Rajagopal SK, Ma Q, Obler D, Shen J, Manichaikul A, Tomita-Mitchell A, Boardman K, Briggs C, Garg V, Srivastava D, Goldmuntz E, Broman KW, Benson DW, Smoot LB, Pu WT. Spectrum of heart disease associated with murine and human GATA4 mutation. Journal of Molecular and Cellular Cardiology. 43: 677-85. PMID 17643447 DOI: 10.1016/j.yjmcc.2007.06.004  0.56
2007 Sen S, Satagopan JM, Broman KW, Churchill GA. R/qtlDesign: Inbred line cross experimental design Mammalian Genome. 18: 87-93. PMID 17347894 DOI: 10.1007/s00335-006-0090-y  0.56
2007 Lemmerhirt HL, Broman KW, Shavit JA, Ginsburg D. Genetic regulation of plasma von Willebrand factor levels: Quantitative trait loci analysis in a mouse model Journal of Thrombosis and Haemostasis. 5: 329-335. PMID 17155961 DOI: 10.1111/j.1538-7836.2007.02325.x  0.56
2007 Teuscher F, Broman KW. Haplotype probabilities for multiple-strain recombinant inbred lines. Genetics. 175: 1267-74. PMID 17151250 DOI: 10.1534/genetics.106.064063  0.56
2007 Nichols KM, Broman KW, Sundin K, Young JM, Wheeler PA, Thorgaard GH. Quantitative trait loci x maternal cytoplasmic environment interaction for development rate in Oncorhynchus mykiss. Genetics. 175: 335-47. PMID 17057232 DOI: 10.1534/genetics.106.064311  0.56
2007 Broman KW, Heath SC. Managing and Manipulating Genetic Data Bioinformatics For Geneticists: a Bioinformatics Primer For the Analysis of Genetic Data: Second Edition. 17-31. DOI: 10.1002/9780470059180.ch2  0.56
2006 Broman KW, Sen S, Owens SE, Manichaikul A, Southard-Smith EM, Churchill GA. The X chromosome in quantitative trait locus mapping. Genetics. 174: 2151-8. PMID 17028340 DOI: 10.1534/genetics.106.061176  0.56
2006 Kess D, Lindqvist AK, Peters T, Wang H, Zamek J, Nischt R, Broman KW, Blakytny R, Krieg T, Holmdahl R, Scharffetter-Kochanek K. Identification of susceptibility loci for skin disease in a murine psoriasis model. Journal of Immunology (Baltimore, Md. : 1950). 177: 4612-9. PMID 16982899  0.56
2006 Shrestha S, Smith MW, Broman KW, Farzadegan H, Vlahov D, Strathdee SA. Multiperson use of syringes among injection drug users in a needle exchange program: a gene-based molecular epidemiologic analysis. Journal of Acquired Immune Deficiency Syndromes (1999). 43: 335-43. PMID 16980914 DOI: 10.1097/01.qai.0000230528.25083.0b  0.56
2006 Sundin OH, Broman KW, Chang HH, Vito EC, Stark WJ, Gottsch JD. A common locus for late-onset Fuchs corneal dystrophy maps to 18q21.2-q21.32. Investigative Ophthalmology & Visual Science. 47: 3919-26. PMID 16936105 DOI: 10.1167/iovs.05-1619  0.56
2006 Grant GR, Robinson SW, Edwards RE, Clothier B, Davies R, Judah DJ, Broman KW, Smith AG. Multiple polymorphic loci determine basal hepatic and splenic iron status in mice. Hepatology (Baltimore, Md.). 44: 174-85. PMID 16799992 DOI: 10.1002/hep.21233  0.56
2006 Manichaikul A, Dupuis J, Sen S, Broman KW. Poor performance of bootstrap confidence intervals for the location of a quantitative trait locus. Genetics. 174: 481-9. PMID 16783000 DOI: 10.1534/genetics.106.061549  0.56
2006 Feenstra B, Skovgaard IM, Broman KW. Mapping quantitative trait loci by an extension of the Haley-Knott regression method using estimating equations. Genetics. 173: 2269-82. PMID 16702423 DOI: 10.1534/genetics.106.058537  0.56
2006 Chadwick LH, Pertz LM, Broman KW, Bartolomei MS, Willard HF. Genetic control of X chromosome inactivation in mice: Definition of the Xce candidate interval Genetics. 173: 2103-2110. PMID 16582439 DOI: 10.1534/genetics.105.054882  0.56
2006 Orgogozo V, Broman KW, Stern DL. High-resolution quantitative trait locus mapping reveals sign epistasis controlling ovariole number between two Drosophila species. Genetics. 173: 197-205. PMID 16489225 DOI: 10.1534/genetics.105.054098  0.56
2006 Shrestha S, Strathdee SA, Broman KW, Smith MW. Unknown biological mixtures evaluation using STR analytical quantification. Electrophoresis. 27: 409-15. PMID 16437418 DOI: 10.1002/elps.200500502  0.56
2006 Reilly KM, Broman KW, Bronson RT, Tsang S, Loisel DA, Christy ES, Sun Z, Diehl J, Munroe DJ, Tuskan RG. An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model. Cancer Research. 66: 62-8. PMID 16397217 DOI: 10.1158/0008-5472.CAN-05-1480  0.56
2006 Sundin OH, Jun AS, Broman KW, Liu SH, Sheehan SE, Vito EC, Stark WJ, Gottsch JD. Linkage of late-onset Fuchs corneal dystrophy to a novel locus at 13pTel-13q12.13. Investigative Ophthalmology & Visual Science. 47: 140-5. PMID 16384955 DOI: 10.1167/iovs.05-0578  0.56
2005 Sundin OH, Leppert GS, Silva ED, Yang JM, Dharmaraj S, Maumenee IH, Santos LC, Parsa CF, Traboulsi EI, Broman KW, Dibernardo C, Sunness JS, Toy J, Weinberg EM. Extreme hyperopia is the result of null mutations in MFRP, which encodes a Frizzled-related protein. Proceedings of the National Academy of Sciences of the United States of America. 102: 9553-8. PMID 15976030 DOI: 10.1073/pnas.0501451102  0.56
2005 Gottsch JD, Sundin OH, Liu SH, Jun AS, Broman KW, Stark WJ, Vito EC, Narang AK, Thompson JM, Magovern M. Inheritance of a novel COL8A2 mutation defines a distinct early-onset subtype of fuchs corneal dystrophy. Investigative Ophthalmology & Visual Science. 46: 1934-9. PMID 15914606 DOI: 10.1167/iovs.04-0937  0.56
2005 Owens SE, Broman KW, Wiltshire T, Elmore JB, Bradley KM, Smith JR, Southard-Smith EM. Genome-wide linkage identifies novel modifier loci of aganglionosis in the Sox10Dom model of Hirschsprung disease. Human Molecular Genetics. 14: 1549-58. PMID 15843399 DOI: 10.1093/hmg/ddi163  0.56
2005 Broman KW. Mapping expression in randomized rodent genomes. Nature Genetics. 37: 209-10. PMID 15731750 DOI: 10.1038/ng0305-209  0.56
2005 Guler ML, Ligons DL, Wang Y, Bianco M, Broman KW, Rose NR. Two autoimmune diabetes loci influencing T cell apoptosis control susceptibility to experimental autoimmune myocarditis. Journal of Immunology (Baltimore, Md. : 1950). 174: 2167-73. PMID 15699148  0.56
2005 Congdon N, Broman KW, Lai H, Munoz B, Bowie H, Gilbert D, Wojciechowski R, West SK. Cortical, but not posterior subcapsular, cataract shows significant familial aggregation in an older population after adjustment for possible shared environmental factors. Ophthalmology. 112: 73-7. PMID 15629823 DOI: 10.1016/j.ophtha.2004.07.012  0.56
2005 Broman KW. The genomes of recombinant inbred lines. Genetics. 169: 1133-46. PMID 15545647 DOI: 10.1534/genetics.104.035212  0.56
2005 Chen WM, Broman KW, Liang KY. Power and robustness of linkage tests for quantitative traits in general pedigrees. Genetic Epidemiology. 28: 11-23. PMID 15493059 DOI: 10.1002/gepi.20034  0.56
2004 Chen S, Wang W, Broman KW, Katki HA, Parmigiani G. BayesMendel: an R environment for Mendelian risk prediction. Statistical Applications in Genetics and Molecular Biology. 3: Article21. PMID 16646800 DOI: 10.2202/1544-6115.1063  0.56
2004 Broman KW, Feingold E. SNPs made routine. Nature Methods. 1: 104-5. PMID 15782170 DOI: 10.1038/nmeth1104-104  0.56
2004 Boyadjiev SA, Dodson JL, Radford CL, Ashrafi GH, Beaty TH, Mathews RI, Broman KW, Gearhart JP. Clinical and molecular characterization of the bladder exstrophy-epispadias complex: analysis of 232 families. Bju International. 94: 1337-43. PMID 15610117 DOI: 10.1111/j.1464-410X.2004.05170.x  0.56
2004 Sieberts SK, Broman KW, Gudbjartsson DF. "Bias toward the null" means reduced power. American Journal of Human Genetics. 75: 720-2; author reply . PMID 15338459 DOI: 10.1086/424756  0.56
2004 Mukhopadhyay I, Feingold E, Weeks DE, Visscher PM, Wray NR, Sieberts SK, Broman KW, Gudbjartsson DF, Abecasis G, Cox N, Daly MJ, Kruglyak L, Laird N, Markianos K, Patterson N, et al. No "bias" toward the null hypothesis in most conventional multipoint nonparametric linkage analyses [1] (multiple letters) American Journal of Human Genetics. 75: 716-727. PMID 15338457 DOI: 10.1086/424754  0.56
2004 Neff MW, Robertson KR, Wong AK, Safra N, Broman KW, Slatkin M, Mealey KL, Pedersen NC. Breed distribution and history of canine mdr1-1Delta, a pharmacogenetic mutation that marks the emergence of breeds from the collie lineage. Proceedings of the National Academy of Sciences of the United States of America. 101: 11725-30. PMID 15289602 DOI: 10.1073/pnas.0402374101  0.56
2004 Congdon N, Broman KW, Lai H, Munoz B, Bowie H, Gilber D, Wojciechowski R, Alston C, West SK. Nuclear cataract shows significant familial aggregation in an older population after adjustment for possible shared environmental factors. Investigative Ophthalmology & Visual Science. 45: 2182-6. PMID 15223793 DOI: 10.1167/iovs.03-1163  0.56
2004 Tankersley CG, Campen M, Bierman A, Flanders SE, Broman KW, Rabold R. Particle effects on heart-rate regulation in senescent mice. Inhalation Toxicology. 16: 381-90. PMID 15204754 DOI: 10.1080/08958370490439551  0.56
2004 Chen WM, Broman KW, Liang KY. Quantitative trait linkage analysis by generalized estimating equations: unification of variance components and Haseman-Elston regression. Genetic Epidemiology. 26: 265-72. PMID 15095386 DOI: 10.1002/gepi.10315  0.56
2004 Kieffer TL, Finucane MM, Nettles RE, Quinn TC, Broman KW, Ray SC, Persaud D, Siliciano RF. Genotypic analysis of HIV-1 drug resistance at the limit of detection: virus production without evolution in treated adults with undetectable HIV loads. The Journal of Infectious Diseases. 189: 1452-65. PMID 15073683 DOI: 10.1086/382488  0.56
2004 Sivagnanasundaram S, Broman KW, Liu M, Petronis A. Quasi-linkage: a confounding factor in linkage analysis of complex diseases? Human Genetics. 114: 588-93. PMID 15045582 DOI: 10.1007/s00439-004-1109-7  0.56
2004 Tankersley CG, Broman KW. Interactions in hypoxic and hypercapnic breathing are genetically linked to mouse chromosomes 1 and 5. Journal of Applied Physiology (Bethesda, Md. : 1985). 97: 77-84. PMID 14978007 DOI: 10.1152/japplphysiol.01102.2003  0.56
2003 Lidman O, Swanberg M, Horvath L, Broman KW, Olsson T, Piehl F. Discrete gene loci regulate neurodegeneration, lymphocyte infiltration, and major histocompatibility complex class II expression in the CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9817-23. PMID 14586010  0.56
2003 Denny P, Hopes E, Gingles N, Broman KW, McPheat W, Morten J, Alexander J, Andrew PW, Brown SD. A major locus conferring susceptibility to infection by Streptococcus pneumoniae in mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 14: 448-53. PMID 12925893 DOI: 10.1007/s00335-002-2261-9  0.56
2003 Glaser RL, Broman KW, Schulman RL, Eskenazi B, Wyrobek AJ, Jabs EW. The paternal-age effect in Apert syndrome is due, in part, to the increased frequency of mutations in sperm. American Journal of Human Genetics. 73: 939-47. PMID 12900791 DOI: 10.1086/378419  0.56
2003 Lamichhane G, Zignol M, Blades NJ, Geiman DE, Dougherty A, Grosset J, Broman KW, Bishai WR. A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: application to Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 100: 7213-8. PMID 12775759 DOI: 10.1073/pnas.1231432100  0.56
2003 Broman KW, Wu H, Sen S, Churchill GA. R/qtl: QTL mapping in experimental crosses Bioinformatics. 19: 889-890. PMID 12724300 DOI: 10.1093/bioinformatics/btg112  0.56
2003 Broman KW. Mapping quantitative trait loci in the case of a spike in the phenotype distribution Genetics. 163: 1169-1175. PMID 12663553  0.56
2003 Broman KW, Caffo BS. Simulation-based P values: Response to north et al. [1] American Journal of Human Genetics. 72: 496. PMID 12596792  0.56
2003 Becanovic K, Wallstrom E, Kornek B, Glaser A, Broman KW, Dahlman I, Olofsson P, Holmdahl R, Luthman H, Lassmann H, Olsson T. New loci regulating rat myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis Journal of Immunology. 170: 1062-1069. PMID 12517974  0.56
2002 Morrison IM, Becorft DMO, Ravenel JD, Feinberg AP, Perlman J, Broman KW. Re: Loss of imprinting of insulin-like growth factor-II (IGF-2) gene in distinguishing specific biologic substypes of wilms tumor (multiple letters) [3] Journal of the National Cancer Institute. 94: 1809-1810. PMID 12464656  0.56
2002 Jun AS, Broman KW, Do DV, Akpek EK, Stark WJ, Gottsch JD. Endothelial dystrophy, iris hypoplasia, congenital cataract, and stromal thinning (EDICT) syndrome maps to chromosome 15q22.1-q25.3 American Journal of Ophthalmology. 134: 172-176. PMID 12140022 DOI: 10.1016/S0002-9394(02)01401-0  0.56
2002 Broman KW, Rowe LB, Churchill GA, Paigen K. Crossover interference in the mouse Genetics. 160: 1123-1131. PMID 11901128  0.56
2002 Balding DJ, Carothers AD, Marchini JL, Cardon LR, Vetta A, Griffiths B, Weir BS, Hill WG, Goldstein D, Strimmer K, Myers S, Beaumont MA, Glasbey CA, Mayer CD, Richardson S, ... ... Broman KW, et al. Discussion on the meeting on 'statistical modelling and analysis of genetic data' Journal of the Royal Statistical Society. Series B: Statistical Methodology. 64: 737-775. DOI: 10.1111/1467-9868.00359  0.56
2001 Hunter KW, Broman KW, Voyer TL, Lukes L, Cozma D, Debies MT, Rouse J, Welch DR. Predisposition to efficient mammary tumor metastatic progression is linked to the breast cancer metastasis suppressor gene Brms1. Cancer Research. 61: 8866-72. PMID 11751410  0.56
2001 Ravenel JD, Broman KW, Perlman EJ, Niemitz EL, Jayawardena TM, Bell DW, Haber DA, Uejima H, Feinberg AP. Loss of imprinting of insulin-like growth factor-II (IGF2) gene in distinguishing specific biologic subtypes of Wilms tumor. Journal of the National Cancer Institute. 93: 1698-703. PMID 11717330  0.56
2001 Broman KW. Review of Statistical Methods for QTL Mapping in Experimental Crosses Lab Animal. 30: 44-52. PMID 11469113  0.56
2001 Broman KW. Estimation of allele frequencies with data on sibships Genetic Epidemiology. 20: 307-315. PMID 11255240 DOI: 10.1002/gepi.2  0.56
2001 Boyartchuk VL, Broman KW, Mosher RE, D'Orazio SEF, Starnbach MN, Dietrich WF. Multigenic control of Listeria monocytogenes susceptibility in mice Nature Genetics. 27: 259-260. PMID 11242105 DOI: 10.1038/85812  0.56
2001 Yu A, Zhao C, Fan Y, Jang W, Mungall AJ, Deloukas P, Olsen A, Doggett NA, Ghebranious N, Broman KW, Weber JL. Comparison of human genetic and sequence-based physical maps. Nature. 409: 951-3. PMID 11237020 DOI: 10.1038/35057185  0.56
2001 Giglio S, Broman KW, Matsumoto N, Calvari V, Gimelli G, Neumann T, Ohashi H, Voullaire L, Larizza D, Giorda R, Weber JL, Ledbetter DH, Zuffardi O. Olfactory receptor-gene clusters, genomic-inversion polymorphisms, and common chromosome rearrangements. American Journal of Human Genetics. 68: 874-83. PMID 11231899 DOI: 10.1086/319506  0.56
2001 Lichter-Konecki U, Broman KW, Blau EB, Konecki DS. Genetic and physical mapping of the locus for autosomal dominant renal Fanconi syndrome, on chromosome 15q15.3 American Journal of Human Genetics. 68: 264-268. PMID 11090339 DOI: 10.1086/316923  0.56
2001 Weber JL, Broman KW. Genotyping for human whole-genome scans: past, present, and future. Advances in Genetics. 42: 77-96. PMID 11037315  0.56
2000 Witte JS, Goddard KA, Conti DV, Elston RC, Lin J, Suarez BK, Broman KW, Burmester JK, Weber JL, Catalona WJ. Genomewide scan for prostate cancer-aggressiveness loci. American Journal of Human Genetics. 67: 92-9. PMID 10825281 DOI: 10.1086/302960  0.56
2000 Broman KW, Weber JL. Characterization of human crossover interference. American Journal of Human Genetics. 66: 1911-26. PMID 10801387 DOI: 10.1086/302923  0.56
2000 Suarez BK, Lin J, Burmester JK, Broman KW, Weber JL, Banerjee TK, Goddard KA, Witte JS, Elston RC, Catalona WJ. A genome screen of multiplex sibships with prostate cancer. American Journal of Human Genetics. 66: 933-44. PMID 10712208 DOI: 10.1086/302818  0.56
2000 Brown AS, Feingold E, Broman KW, Sherman SL. Genome-wide variation in recombination in female meiosis: a risk factor for non-disjunction of chromosome 21. Human Molecular Genetics. 9: 515-23. PMID 10699174  0.56
1999 Broman KW. Cleaning genotype data Genetic Epidemiology. 17. PMID 10597416  0.56
1999 Broman KW, Weber JL. Long homozygous chromosomal segments in reference families from the centre d'Etude du polymorphisme humain. American Journal of Human Genetics. 65: 1493-500. PMID 10577902 DOI: 10.1086/302661  0.56
1999 Broman KW, Weber JL. Method for constructing confidently ordered linkage maps. Genetic Epidemiology. 16: 337-43. PMID 10207715 DOI: 10.1002/(SICI)1098-2272(1999)16:4<337::AID-GEPI1>3.0.CO;2-T  0.56
1999 Neff MW, Broman KW, Mellersh CS, Ray K, Acland GM, Aguirre GD, Ziegle JS, Ostrander EA, Rine J. A second-generation genetic linkage map of the domestic dog, Canis familiaris Genetics. 151: 803-820. PMID 9927471  0.56
1998 Broman KW, Weber JL. Estimation of pairwise relationships in the presence of genotyping errors. American Journal of Human Genetics. 63: 1563-4. PMID 9792888 DOI: 10.1086/302112  0.56
1998 Broman KW, Murray JC, Sheffield VC, White RL, Weber JL. Comprehensive human genetic maps: individual and sex-specific variation in recombination. American Journal of Human Genetics. 63: 861-9. PMID 9718341 DOI: 10.1086/302011  0.56
1996 Dernburg AF, Broman KW, Fung JC, Marshall WF, Philips J, Agard DA, Sedat JW. Perturbation of nuclear architecture by long-distance chromosome interactions. Cell. 85: 745-59. PMID 8646782 DOI: 10.1016/S0092-8674(00)81240-4  0.56
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