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Bert W. O'Malley, MD - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
 1969-1973 Vanderbilt University School of Medicine, Nashville, TN, United States 
 1973- Molecular and Cell Biology Baylor College of Medicine, Houston, TX 
Area:
Hormone Action and Gene Expression: Coactivators and Corepressors
Website:
https://www.bcm.edu/people/view/bert-o-malley-m-d/b1606234-ffed-11e2-be68-080027880ca6
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418 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Maurya VK, Szwarc MM, Lonard DM, Gibbons WE, Wu SP, O'Malley BW, DeMayo FJ, Lydon JP. Decidualization of human endometrial stromal cells requires steroid receptor coactivator-3. Frontiers in Reproductive Health. 4: 1033581. PMID 36505394 DOI: 10.3389/frph.2022.1033581  0.313
2021 Yi P, Yu X, Wang Z, O'Malley BW. Steroid receptor-coregulator transcriptional complexes: new insights from CryoEM. Essays in Biochemistry. PMID 34061186 DOI: 10.1042/EBC20210019  0.312
2021 Nikolai BC, Jain P, Cardenas DL, York B, Feng Q, McKenna NJ, Dasgupta S, Lonard DM, O'Malley BW. Steroid receptor coactivator 3 (SRC-3/AIB1) is enriched and functional in mouse and human Tregs. Scientific Reports. 11: 3441. PMID 33564037 DOI: 10.1038/s41598-021-82945-3  0.779
2020 Yu X, Yi P, Hamilton RA, Shen H, Chen M, Foulds CE, Mancini MA, Ludtke SJ, Wang Z, O'Malley BW. Structural Insights of Transcriptionally Active, Full-Length Androgen Receptor Coactivator Complexes. Molecular Cell. PMID 32668201 DOI: 10.1016/J.Molcel.2020.06.031  0.319
2020 O'Malley BW. 90 YEARS OF PROGESTERONE: Reminiscing on the origins of the field of progesterone and estrogen receptor action. Journal of Molecular Endocrinology. 65: C1-C4. PMID 32599564 DOI: 10.1530/Jme-20-0042  0.355
2019 Han SJ, Lee JE, Cho YJ, Park MJ, O'Malley BW. Genomic Function of Estrogen Receptor Beta In Endometriosis. Endocrinology. PMID 31504401 DOI: 10.1210/En.2019-00442  0.372
2019 Kaochar S, Ittmann M, Robertson M, Wang J, Skapura D, Davis C, Ehli E, Freedman M, Coarfa C, O'Malley B, Mitsiades N. Abstract 1565: A novel therapeutic target in lethal prostate cancer in African American males Cancer Research. 79: 1565-1565. DOI: 10.1158/1538-7445.Am2019-1565  0.361
2018 Song X, Chen H, Zhang C, Yu Y, Chen Z, Liang H, Van Buren G, McElhany AL, Fisher WE, Lonard DM, O'Malley BW, Wang J. SRC-3 Inhibition Blocks Tumor Growth of Pancreatic Ductal Adenocarcinoma. Cancer Letters. PMID 30423406 DOI: 10.1016/J.Canlet.2018.11.012  0.312
2018 Szwarc MM, Hai L, Gibbons WE, White LD, Mo Q, Kommagani R, Lanz RB, DeMayo FJ, O'Malley BW, Lydon JP. Retinoid Signaling Controlled by SRC-2 in Decidualization Revealed by Transcriptomics. Reproduction (Cambridge, England). PMID 30072571 DOI: 10.1530/REP-18-0282  0.3
2018 Tanaka K, Martinez GJ, Yan X, Long W, Ichiyama K, Chi X, Kim BS, Reynolds JM, Chung Y, Tanaka S, Liao L, Nakanishi Y, Yoshimura A, Zheng P, Wang X, et al. Regulation of Pathogenic T Helper 17 Cell Differentiation by Steroid Receptor Coactivator-3. Cell Reports. 23: 2318-2329. PMID 29791844 DOI: 10.1016/J.Celrep.2018.04.088  0.337
2018 Gates LA, Gu G, Chen Y, Rohira AD, Lei JT, Hamilton RA, Yu Y, Lonard DM, Wang J, Wang SP, Edwards DG, Lavere PF, Shao J, Yi P, Jain A, et al. Proteomic profiling identifies key coactivators utilized by mutant ERα proteins as potential new therapeutic targets. Oncogene. PMID 29748621 DOI: 10.1038/S41388-018-0284-2  0.485
2018 Cho YJ, Lee JE, Park MJ, O'Malley BW, Han SJ. Bufalin suppresses endometriosis progression by inducing pyroptosis and apoptosis. The Journal of Endocrinology. PMID 29636364 DOI: 10.1530/Joe-17-0700  0.357
2018 Dasgupta S, Rajapakshe K, Zhu B, Nikolai BC, Yi P, Putluri N, Choi JM, Jung SY, Coarfa C, Westbrook TF, Zhang XH, Foulds CE, Tsai SY, Tsai MJ, O'Malley BW. Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer. Nature. PMID 29615789 DOI: 10.1038/S41586-018-0018-1  0.803
2018 Padmanabhan A, Candelaria N, Wong KK, Nikolai BC, Lonard DM, O'Malley BW, Richards JS. USP15-dependent lysosomal pathway controls p53-R175H turnover in ovarian cancer cells. Nature Communications. 9: 1270. PMID 29593334 DOI: 10.1038/S41467-018-03599-W  0.767
2018 Singh R, Karri D, Shao J, Dasgupta S, Huang S, Edwards DP, O'Malley BW, Yi P. Abstract 1084: TRAF4-mediated NGF receptor TrkA ubiquitination regulates prostate cancer metastasis Cancer Research. 78: 1084-1084. DOI: 10.1158/1538-7445.Am2018-1084  0.368
2017 Camden AJ, Szwarc MM, Chadchan SB, DeMayo FJ, O'Malley BW, Lydon JP, Kommagani R. Growth regulation by estrogen in breast cancer 1 (GREB1) is a novel progesterone-responsive gene required for human endometrial stromal decidualization. Molecular Human Reproduction. 23: 646-653. PMID 28911214 DOI: 10.1093/Molehr/Gax045  0.353
2017 Yi P, Wang Z, Feng Q, Chou CK, Pintilie GD, Shen H, Foulds CE, Fan G, Serysheva I, Ludtke SJ, Schmid MF, Hung MC, Chiu W, O'Malley BW. Structural and Functional Impacts of ER Coactivator Sequential Recruitment. Molecular Cell. 67: 733-743.e4. PMID 28844863 DOI: 10.1016/J.Molcel.2017.07.026  0.427
2017 Zhang Z, Nikolai BC, Gates LA, Jung SY, Siwak EB, He B, Rice AP, O'Malley BW, Feng Q. Crosstalk between histone modifications indicates that inhibition of arginine methyltransferase CARM1 activity reverses HIV latency. Nucleic Acids Research. 45: 9348-9360. PMID 28637181 DOI: 10.1093/nar/gkx550  0.761
2017 Rohira AD, Yan F, Wang L, Wang J, Zhou S, Lu A, Yu Y, Xu J, Lonard DM, O'Malley BW. Targeting SRC Coactivators Blocks the Tumor-Initiating Capacity of Cancer Stem-like Cells. Cancer Research. 77: 4293-4304. PMID 28611048 DOI: 10.1158/0008-5472.Can-16-2982  0.328
2017 Dasgupta S, Zhu B, Nikolai B, Putluri N, Foulds C, Tsai S, Tsai M, O'Malley B. Abstract P3-05-01: Increased glycolysis directly activates transcriptional coactivator SRC-3 to promote aggressive metastatic breast cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P3-05-01  0.33
2017 Padmanabhan A, Candelaria N, Wong K, Nikolai BC, Lonard D, O'Malley BW, Richards JS. Abstract 2579: Identifying pathways that regulate the turnover of gain-of-function p53 mutant proteins in ovarian cancer cells Cancer Research. 77: 2579-2579. DOI: 10.1158/1538-7445.Am2017-2579  0.331
2016 Lonard DM, O'Malley BW. Molecular Pathways: Targeting Steroid Receptor Coactivators in Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 22: 5403-5407. PMID 27654711 DOI: 10.1158/1078-0432.Ccr-15-1958  0.396
2016 Fleet T, Stashi E, Zhu B, Rajapakshe K, Marcelo KL, Kettner NM, Gorman BK, Coarfa C, Fu L, O'Malley BW, York B. Genetic and Environmental Models of Circadian Disruption Link SRC-2 Function to Hepatic Pathology. Journal of Biological Rhythms. 31: 443-60. PMID 27432117 DOI: 10.1177/0748730416657921  0.306
2016 Wang L, Lonard DM, O'Malley BW. The Role of Steroid Receptor Coactivators in Hormone Dependent Cancers and Their Potential as Therapeutic Targets. Hormones & Cancer. 7: 229-35. PMID 27125199 DOI: 10.1007/s12672-016-0261-6  0.311
2016 Song X, Chen J, Zhao M, Zhang C, Yu Y, Lonard DM, Chow DC, Palzkill T, Xu J, O'Malley BW, Wang J. Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3. Proceedings of the National Academy of Sciences of the United States of America. 113: 4970-5. PMID 27084884 DOI: 10.1073/Pnas.1604274113  0.35
2016 Xu J, Zhou L, Ji L, Chen F, Fortmann K, Zhang K, Liu Q, Li K, Wang W, Wang H, Xie W, Wang Q, Liu J, Zheng B, Zhang P, et al. The REGγ-proteasome forms a regulatory circuit with IκBɛ and NFκB in experimental colitis. Nature Communications. 7: 10761. PMID 26899380 DOI: 10.1038/Ncomms10761  0.318
2016 Nikolai BC, Lanz RB, York B, Dasgupta S, Mitsiades N, Creighton CJ, Tsimelzon A, Hilsenbeck SG, Lonard DM, Smith CL, O'Malley BW. HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes. Cancer Research. 76: 1463-75. PMID 26833126 DOI: 10.1158/0008-5472.Can-15-2383  0.802
2015 Szwarc MM, Kommagani R, Jeong JW, Wu SP, Tsai SY, Tsai MJ, O'Malley BW, DeMayo FJ, Lydon JP. Correction: Perturbing the Cellular Levels of Steroid Receptor Coactivator-2 Impairs Murine Endometrial Function. Plos One. 10: e0143652. PMID 26580555 DOI: 10.1371/Journal.Pone.0143652  0.374
2015 Han SJ, Jung SY, Wu SP, Hawkins SM, Park MJ, Kyo S, Qin J, Lydon JP, Tsai SY, Tsai MJ, DeMayo FJ, O'Malley BW. Estrogen Receptor β Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis. Cell. 163: 960-74. PMID 26544941 DOI: 10.1016/J.Cell.2015.10.034  0.352
2015 Szwarc MM, Lydon JP, O'Malley BW. Reprint of "Steroid receptor coactivators as therapeutic targets in the female reproductive system". The Journal of Steroid Biochemistry and Molecular Biology. 153: 144-50. PMID 26291832 DOI: 10.1016/J.Jsbmb.2015.08.012  0.419
2015 Wang L, Yu Y, Chow DC, Yan F, Hsu CC, Stossi F, Mancini MA, Palzkill T, Liao L, Zhou S, Xu J, Lonard DM, O'Malley BW. Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death. Cancer Cell. 28: 240-52. PMID 26267537 DOI: 10.1016/J.Ccell.2015.07.005  0.351
2015 Szwarc MM, Lydon JP, O'Malley BW. Steroid receptor coactivators as therapeutic targets in the female reproductive system. The Journal of Steroid Biochemistry and Molecular Biology. 154: 32-8. PMID 26151740 DOI: 10.1016/j.jsbmb.2015.06.010  0.305
2015 Eedunuri VK, Rajapakshe K, Fiskus W, Geng C, Chew SA, Foley C, Shah SS, Shou J, Mohamed JS, Coarfa C, O'Malley BW, Mitsiades N. miR-137 Targets p160 Steroid Receptor Coactivators SRC1, SRC2, and SRC3 and Inhibits Cell Proliferation. Molecular Endocrinology (Baltimore, Md.). 29: 1170-83. PMID 26066330 DOI: 10.1210/Me.2015-1080  0.347
2015 Kang YK, Putluri N, Maity S, Tsimelzon A, Ilkayeva O, Mo Q, Lonard D, Michailidis G, Sreekumar A, Newgard CB, Wang M, Tsai SY, Tsai MJ, O'Malley BW. CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-α-Gabpa and stress-induced adaptive responses via NF-κB-cMYC. Plos Genetics. 11: e1005116. PMID 25830341 DOI: 10.1371/Journal.Pgen.1005116  0.56
2015 Lonard DM, Xu J, O'Malley BW. Bufalin is a steroid receptor coactivator inhibitor-response. Cancer Research. 75: 1157. PMID 25736684 DOI: 10.1158/0008-5472.Can-14-2648  0.371
2015 Yi P, Wang Z, Feng Q, Pintilie GD, Foulds CE, Lanz RB, Ludtke SJ, Schmid MF, Chiu W, O'Malley BW. Structure of a biologically active estrogen receptor-coactivator complex on DNA. Molecular Cell. 57: 1047-58. PMID 25728767 DOI: 10.1016/J.Molcel.2015.01.025  0.323
2015 Begum K, O'Malley BW, DeMayo FJ, Overbeek P. 337. CRISPR/Cas9 Mediated Highly Efficient Genome Engineering in Mouse Embryos Molecular Therapy. 23: S135. DOI: 10.1016/S1525-0016(16)33946-6  0.327
2014 He B, Lanz RB, Fiskus W, Geng C, Yi P, Hartig SM, Rajapakshe K, Shou J, Wei L, Shah SS, Foley C, Chew SA, Eedunuri VK, Bedoya DJ, Feng Q, et al. GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex. Proceedings of the National Academy of Sciences of the United States of America. 111: 18261-6. PMID 25489091 DOI: 10.1073/Pnas.1421415111  0.417
2014 Tannour-Louet M, York B, Tang K, Stashi E, Bouguerra H, Zhou S, Yu H, Wong LJ, Stevens RD, Xu J, Newgard CB, O'Malley BW, Louet JF. Hepatic SRC-1 activity orchestrates transcriptional circuitries of amino acid pathways with potential relevance for human metabolic pathogenesis. Molecular Endocrinology (Baltimore, Md.). 28: 1707-18. PMID 25148457 DOI: 10.1210/Me.2014-1083  0.371
2014 Gustafsson JA, Katzenellenbogen B, Jameson JL, Roth J, Melmed S, McDonnell D, Wartofsky L, Crowley WF, Griz LH, Becker C, Moore DD, Drucker D, Singh N, O'Malley B. Endocrine Society 2014 Laureate Awards. Hormones & Cancer. 5: 339-55. PMID 25091407 DOI: 10.1007/S12672-014-0193-Y  0.455
2014 Yamagata K, Fujiyama S, Ito S, Ueda T, Murata T, Naitou M, Takeyama Ki, Minami Y, O'Malley BW, Kato S. Retraction Notice to: Maturation of MicroRNA Is Hormonally Regulated by a Nuclear Receptor Molecular Cell. 54: 536. PMID 24932469 DOI: 10.1016/j.molcel.2014.04.018  0.309
2014 Szwarc MM, Kommagani R, Jeong JW, Wu SP, Tsai SY, Tsai MJ, O'Malley BW, DeMayo FJ, Lydon JP. Perturbing the cellular levels of steroid receptor coactivator-2 impairs murine endometrial function. Plos One. 9: e98664. PMID 24905738 DOI: 10.1371/Journal.Pone.0098664  0.423
2014 Feng Q, Zhang Z, Shea MJ, Creighton CJ, Coarfa C, Hilsenbeck SG, Lanz R, He B, Wang L, Fu X, Nardone A, Song Y, Bradner J, Mitsiades N, Mitsiades CS, et al. An epigenomic approach to therapy for tamoxifen-resistant breast cancer. Cell Research. 24: 809-19. PMID 24874954 DOI: 10.1038/Cr.2014.71  0.344
2014 Reineke EL, Benham A, Soibam B, Stashi E, Taegtmeyer H, Entman ML, Schwartz RJ, O'Malley BW. Steroid receptor coactivator-2 is a dual regulator of cardiac transcription factor function. The Journal of Biological Chemistry. 289: 17721-31. PMID 24811170 DOI: 10.1074/Jbc.M113.539908  0.373
2014 Yan F, Yu Y, Chow DC, Palzkill T, Madoux F, Hodder P, Chase P, Griffin PR, O'Malley BW, Lonard DM. Identification of verrucarin a as a potent and selective steroid receptor coactivator-3 small molecule inhibitor. Plos One. 9: e95243. PMID 24743578 DOI: 10.1371/Journal.Pone.0095243  0.437
2014 Han SJ, O'Malley BW. The dynamics of nuclear receptors and nuclear receptor coregulators in the pathogenesis of endometriosis. Human Reproduction Update. 20: 467-84. PMID 24634322 DOI: 10.1093/Humupd/Dmu002  0.349
2014 Wang W, Bian K, Vallabhaneni S, Zhang B, Wu RC, O'Malley BW, Long W. ERK3 promotes endothelial cell functions by upregulating SRC-3/SP1-mediated VEGFR2 expression. Journal of Cellular Physiology. 229: 1529-37. PMID 24585635 DOI: 10.1002/Jcp.24596  0.383
2014 Kommagani R, Szwarc MM, Kovanci E, Creighton CJ, O'Malley BW, Demayo FJ, Lydon JP. A murine uterine transcriptome, responsive to steroid receptor coactivator-2, reveals transcription factor 23 as essential for decidualization of human endometrial stromal cells. Biology of Reproduction. 90: 75. PMID 24571987 DOI: 10.1095/Biolreprod.114.117531  0.459
2014 Kang YK, Jung SY, Qin J, Li C, Tsai SY, Tsai MJ, O'Malley BW. E2/Estrogen receptor/sjogren syndrome-associated autoantigen relieves coactivator activator-induced G1/S arrest to promote breast tumorigenicity. Molecular and Cellular Biology. 34: 1670-81. PMID 24567374 DOI: 10.1128/Mcb.01564-13  0.628
2014 Stashi E, Lanz RB, Mao J, Michailidis G, Zhu B, Kettner NM, Putluri N, Reineke EL, Reineke LC, Dasgupta S, Dean A, Stevenson CR, Sivasubramanian N, Sreekumar A, Demayo F, et al. SRC-2 is an essential coactivator for orchestrating metabolism and circadian rhythm. Cell Reports. 6: 633-45. PMID 24529706 DOI: 10.1016/J.Celrep.2014.01.027  0.349
2014 Motamed M, Rajapakshe KI, Hartig SM, Coarfa C, Moses RE, Lonard DM, O'Malley BW. Steroid receptor coactivator 1 is an integrator of glucose and NAD+/NADH homeostasis. Molecular Endocrinology (Baltimore, Md.). 28: 395-405. PMID 24438340 DOI: 10.1210/Me.2013-1404  0.347
2014 Wang Y, Lonard DM, Yu Y, Chow DC, Palzkill TG, Wang J, Qi R, Matzuk AJ, Song X, Madoux F, Hodder P, Chase P, Griffin PR, Zhou S, Liao L, et al. Bufalin is a potent small-molecule inhibitor of the steroid receptor coactivators SRC-3 and SRC-1. Cancer Research. 74: 1506-1517. PMID 24390736 DOI: 10.1158/0008-5472.Can-13-2939  0.383
2013 Kommagani R, Szwarc MM, Kovanci E, Gibbons WE, Putluri N, Maity S, Creighton CJ, Sreekumar A, DeMayo FJ, Lydon JP, O'Malley BW. Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization. Plos Genetics. 9: e1003900. PMID 24204309 DOI: 10.1371/Journal.Pgen.1003900  0.377
2013 Savulescu D, Feng J, Ping YS, Mai O, Boehm U, He B, O'Malley BW, Melamed P. Gonadotropin-releasing hormone-regulated prohibitin mediates apoptosis of the gonadotrope cells. Molecular Endocrinology (Baltimore, Md.). 27: 1856-70. PMID 24085822 DOI: 10.1210/Me.2013-1210  0.364
2013 Stashi E, Wang L, Mani SK, York B, O'Malley BW. Research resource: loss of the steroid receptor coactivators confers neurobehavioral consequences. Molecular Endocrinology (Baltimore, Md.). 27: 1776-87. PMID 23927929 DOI: 10.1210/Me.2013-1192  0.346
2013 Bhat-Nakshatri P, Song EK, Collins NR, Uversky VN, Dunker AK, O'Malley BW, Geistlinger TR, Carroll JS, Brown M, Nakshatri H. Interplay between estrogen receptor and AKT in estradiol-induced alternative splicing. Bmc Medical Genomics. 6: 21. PMID 23758675 DOI: 10.1186/1755-8794-6-21  0.426
2013 Geng C, He B, Xu L, Barbieri CE, Eedunuri VK, Chew SA, Zimmermann M, Bond R, Shou J, Li C, Blattner M, Lonard DM, Demichelis F, Coarfa C, Rubin MA, et al. Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover. Proceedings of the National Academy of Sciences of the United States of America. 110: 6997-7002. PMID 23559371 DOI: 10.1073/Pnas.1304502110  0.307
2013 Yi P, Xia W, Wu RC, Lonard DM, Hung MC, O'Malley BW. SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization. Genes & Development. 27: 274-87. PMID 23388826 DOI: 10.1101/Gad.203760.112  0.39
2013 York B, Sagen JV, Tsimelzon A, Louet JF, Chopra AR, Reineke EL, Zhou S, Stevens RD, Wenner BR, Ilkayeva O, Bain JR, Xu J, Hilsenbeck SG, Newgard CB, O'Malley BW. Research resource: tissue- and pathway-specific metabolomic profiles of the steroid receptor coactivator (SRC) family. Molecular Endocrinology (Baltimore, Md.). 27: 366-80. PMID 23315938 DOI: 10.1210/Me.2012-1324  0.319
2013 Zhu L, Yang Y, Xu P, Zou F, Yan X, Liao L, Xu J, O'Malley BW, Xu Y. Steroid receptor coactivator-1 mediates estrogenic actions to prevent body weight gain in female mice. Endocrinology. 154: 150-8. PMID 23211707 DOI: 10.1210/En.2012-2007  0.413
2013 Carstens R, Huffman K, Wei S, Girard L, Xie Y, Hofmann S, Wistuba I, Fuqua S, Posner B, Gazdar AF, Kliewer S, O'Malley B, Mangelsdorf D, Minna JD. Abstract 1474: An RNAi-based functional classification of lung cancer reveals recurring subgroups strongly correlated with EMT status. Cancer Research. 73: 1474-1474. DOI: 10.1158/1538-7445.Am2013-1474  0.333
2013 Lonard DM, O'Malley BW. Nuclear Receptor Co-regulators Genetic Steroid Disorders. 301-312. DOI: 10.1016/B978-0-12-416006-4.00024-7  0.306
2012 O'Malley BW, Malovannaya A, Qin J. Minireview: nuclear receptor and coregulator proteomics--2012 and beyond. Molecular Endocrinology (Baltimore, Md.). 26: 1646-50. PMID 22745194 DOI: 10.1210/Me.2012-1114  0.343
2012 Han SJ, Hawkins SM, Begum K, Jung SY, Kovanci E, Qin J, Lydon JP, DeMayo FJ, O'Malley BW. A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis. Nature Medicine. 18: 1102-11. PMID 22660634 DOI: 10.1038/Nm.2826  0.364
2012 Liu A, Margaill I, Zhang S, Labombarda F, Coqueran B, Delespierre B, Liere P, Marchand-Leroux C, O'Malley BW, Lydon JP, De Nicola AF, Sitruk-Ware R, Mattern C, Plotkine M, Schumacher M, et al. Progesterone receptors: a key for neuroprotection in experimental stroke. Endocrinology. 153: 3747-57. PMID 22635678 DOI: 10.1210/En.2012-1138  0.31
2012 Park S, Yoon S, Zhao Y, Park SE, Liao L, Xu J, Lydon JP, DeMayo FJ, O'Malley BW, Bagchi MK, Katzenellenbogen BS. Uterine development and fertility are dependent on gene dosage of the nuclear receptor coregulator REA. Endocrinology. 153: 3982-94. PMID 22585830 DOI: 10.1210/En.2012-1044  0.422
2012 York B, Reineke EL, Sagen JV, Nikolai BC, Zhou S, Louet JF, Chopra AR, Chen X, Reed G, Noebels J, Adesina AM, Yu H, Wong LJ, Tsimelzon A, Hilsenbeck S, et al. Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy. Cell Metabolism. 15: 752-63. PMID 22560224 DOI: 10.1016/J.Cmet.2012.03.020  0.782
2012 Long W, Foulds CE, Qin J, Liu J, Ding C, Lonard DM, Solis LM, Wistuba II, Qin J, Tsai SY, Tsai MJ, O'Malley BW. ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion. The Journal of Clinical Investigation. 122: 1869-80. PMID 22505454 DOI: 10.1172/Jci61492  0.33
2012 Wu MY, Fu J, Xu J, O'Malley BW, Wu RC. Steroid receptor coactivator 3 regulates autophagy in breast cancer cells through macrophage migration inhibitory factor. Cell Research. 22: 1003-21. PMID 22430150 DOI: 10.1038/Cr.2012.44  0.376
2012 Hartmaier RJ, Richter AS, Gillihan RM, Sallit JZ, McGuire SE, Wang J, Lee AV, Osborne CK, O'Malley BW, Brown PH, Xu J, Skaar TC, Philips S, Rae JM, Azzouz F, et al. A SNP in steroid receptor coactivator-1 disrupts a GSK3β phosphorylation site and is associated with altered tamoxifen response in bone. Molecular Endocrinology (Baltimore, Md.). 26: 220-7. PMID 22174377 DOI: 10.1210/Me.2011-1032  0.364
2012 Johnson AB, O'Malley BW. Steroid receptor coactivators 1, 2, and 3: critical regulators of nuclear receptor activity and steroid receptor modulator (SRM)-based cancer therapy. Molecular and Cellular Endocrinology. 348: 430-9. PMID 21664237 DOI: 10.1016/j.mce.2011.04.021  0.37
2012 Carstens R, Huffman K, Girard L, Posner B, Erickson H, Wistuba I, Gazdar A, Kliewer S, Fuqua S, O'Malley B, Mangelsdorf D, Minna JD. Abstract 5757: A new functional classification of lung and breast cancers based on siRNA mediated knockdown of 48 NRs and 72 CoRegulators Cancer Research. 72: 5757-5757. DOI: 10.1158/1538-7445.Am2012-5757  0.337
2012 Dasgupta S, Zhang B, Louet J, O'Malley BW. Abstract 5153: Steroid receptor coactivator-2 mediates oncogenic reprogramming of cancer cell metabolism Cancer Research. 72: 5153-5153. DOI: 10.1158/1538-7445.Am2012-5153  0.366
2012 Nikolai BC, Smith CL, O'Malley BW. Abstract 3072: HER2 signaling affects SRC-3 phosphorylation and gene regulatory potential within the cistrome Cancer Research. 72: 3072-3072. DOI: 10.1158/1538-7445.Am2012-3072  0.426
2012 Gu G, Rechoum Y, Covington K, O'Malley B, Mangelsdorf D, Minna J, Fuqua S. Abstract 1083: Nuclear receptors as novel targets in ER negative breast cancer Cancer Research. 72: 1083-1083. DOI: 10.1158/1538-7445.Am2012-1083  0.411
2012 Gu G, Covington K, Rechoum Y, O'Malley B, Mangelsdorf D, Minna J, Webb P, Fuqua S. Abstract P4-08-09: Targeting Thyroid Receptor b in Estrogen Receptor Negative Breast Cancer Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P4-08-09  0.386
2012 Szwarc MM, Kommagani R, Wu S, Tsai SY, Tsai M, O'Malley BW, DeMayo FJ, Lydon JP. Deregulation of Steroid Receptor Coregulator-2 Causes Severe Sub-Fertility and Abnormal Hormone Responsiveness in the Murine Endometrium. Biology of Reproduction. 87: 604-604. DOI: 10.1093/Biolreprod/87.S1.604  0.355
2012 Kommagani R, Szwarc MM, Creighton CJ, DeMayo FJ, Lydon JP, O'Malley BW. Proliferation of Endometrial Stromal Cells Requires Induction of 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase-3 by Steroid Receptor Coregulator-2. Biology of Reproduction. 87: 408-408. DOI: 10.1093/Biolreprod/87.S1.408  0.394
2011 Park S, Zhao Y, Yoon S, Xu J, Liao L, Lydon J, DeMayo F, O'Malley BW, Katzenellenbogen BS. Repressor of estrogen receptor activity (REA) is essential for mammary gland morphogenesis and functional activities: studies in conditional knockout mice. Endocrinology. 152: 4336-49. PMID 21862609 DOI: 10.1210/En.2011-1100  0.396
2011 Johnson AB, O'Malley BW. ERasing breast cancer resistance through the kinome. Nature Medicine. 17: 660-1. PMID 21647142 DOI: 10.1038/Nm0611-660  0.322
2011 Reddy SD, Rayala SK, Ohshiro K, Pakala SB, Kobori N, Dash P, Yun S, Qin J, O'Malley BW, Kumar R. Multiple coregulatory control of tyrosine hydroxylase gene transcription. Proceedings of the National Academy of Sciences of the United States of America. 108: 4200-5. PMID 21368136 DOI: 10.1073/Pnas.1101193108  0.367
2011 He B, Kim TH, Kommagani R, Feng Q, Lanz RB, Jeong JW, DeMayo FJ, Katzenellenbogen BS, Lydon JP, O'Malley BW. Estrogen-regulated prohibitin is required for mouse uterine development and adult function. Endocrinology. 152: 1047-56. PMID 21209023 DOI: 10.1210/En.2010-0732  0.45
2011 Lydon JP, O'Malley BW. Minireview: steroid receptor coactivator-3: a multifarious coregulator in mammary gland metastasis. Endocrinology. 152: 19-25. PMID 21047941 DOI: 10.1210/En.2010-1012  0.377
2011 Covington KR, Gu G, Tsimelzon A, Hilsenbeck S, Brown P, Change J, Osborne CK, Xu J, O'Malley B, Mangelsdorf D, Minna J, Fuqua S. Abstract 2296: Identification of novel nuclear receptor targets in estrogen receptor negative breast cancer Cancer Research. 71: 2296-2296. DOI: 10.1158/1538-7445.Am2011-2296  0.36
2011 O'Malley B. BS2-2: Nuclear Receptor Coactivators: Physiology and Disease. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-Bs2-2  0.4
2011 Szwarc MM, Kommagani R, Wu S, Tsai SY, Tsai M, O'Malley BW, DeMayo FJ, Lydon JP. Tight Control of Steroid Receptor Coregulator-2 Expression Is Required to Maintain Normal Hormone Responsiveness in the Murine Endometrium. Biology of Reproduction. 85: 60-60. DOI: 10.1093/Biolreprod/85.S1.60  0.391
2010 Stanišić V, Lonard DM, O'Malley BW. Estrogen receptor-α: molecular mechanisms and interactions with the ubiquitin proteasome system. Hormone Molecular Biology and Clinical Investigation. 1: 1-9. PMID 25961966 DOI: 10.1515/Hmbci.2010.004  0.439
2010 McKenna NJ, O'Malley BW. SnapShot: Nuclear receptors I. Cell. 142: 822-822.e1. PMID 20813267 DOI: 10.1016/J.Cell.2010.08.026  0.306
2010 York B, Yu C, Sagen JV, Liu Z, Nikolai BC, Wu RC, Finegold M, Xu J, O'Malley BW. Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology. Proceedings of the National Academy of Sciences of the United States of America. 107: 11122-7. PMID 20534466 DOI: 10.1073/Pnas.1005262107  0.79
2010 Long W, O'Malley BW. Crosstalk among nuclear receptor coactivators and a membrane receptor promotes tumor cell growth and migration. Cell Cycle (Georgetown, Tex.). 9: 2269-70. PMID 20519947 DOI: 10.4161/Cc.9.12.12116  0.369
2010 Stanisić V, Lonard DM, O'Malley BW. Modulation of steroid hormone receptor activity. Progress in Brain Research. 181: 153-76. PMID 20478437 DOI: 10.1016/S0079-6123(08)81009-6  0.482
2010 Foulds CE, Tsimelzon A, Long W, Le A, Tsai SY, Tsai MJ, O'Malley BW. Research resource: expression profiling reveals unexpected targets and functions of the human steroid receptor RNA activator (SRA) gene. Molecular Endocrinology (Baltimore, Md.). 24: 1090-105. PMID 20219889 DOI: 10.1210/Me.2009-0427  0.416
2010 Lanz RB, Bulynko Y, Malovannaya A, Labhart P, Wang L, Li W, Qin J, Harper M, O'Malley BW. Global characterization of transcriptional impact of the SRC-3 coregulator. Molecular Endocrinology (Baltimore, Md.). 24: 859-72. PMID 20181721 DOI: 10.1210/Me.2009-0499  0.453
2010 Malik S, Jiang S, Garee JP, Verdin E, Lee AV, O'Malley BW, Zhang M, Belaguli NS, Oesterreich S. Histone deacetylase 7 and FoxA1 in estrogen-mediated repression of RPRM. Molecular and Cellular Biology. 30: 399-412. PMID 19917725 DOI: 10.1128/Mcb.00907-09  0.423
2010 Lonard DM, Kumar R, O'Malley BW. Minireview: the SRC family of coactivators: an entrée to understanding a subset of polygenic diseases? Molecular Endocrinology (Baltimore, Md.). 24: 279-85. PMID 19846539 DOI: 10.1210/Me.2009-0276  0.329
2010 Xu Y, Chen Q, Li W, Su X, Chen T, Liu Y, Zhao Y, O'Malley BW, Yu C. Abstract 3093: Overexpression of transcriptional coactivator AIB1 promotes hepatocellular carcinoma progression by enhancing cell proliferation and invasiveness Cancer Research. 70: 3093-3093. DOI: 10.1158/1538-7445.Am10-3093  0.31
2010 Long W, Medina D, Tsai S, Tsai M, O'Malley B. Abstract 3092: The roles of SRC-3 and its isoform SRC-3Δ4 during the progression of DCIS to invasive breast cancer Cancer Research. 70: 3092-3092. DOI: 10.1158/1538-7445.Am10-3092  0.329
2009 Lonard DM, O'Malley BW. Emerging roles of the ubiquitin proteasome system in nuclear hormone receptor signaling. Progress in Molecular Biology and Translational Science. 87: 117-35. PMID 20374703 DOI: 10.1016/S1877-1173(09)87004-X  0.408
2009 Han SJ, O'Malley BW, DeMayo FJ. An estrogen receptor alpha activity indicator model in mice. Genesis (New York, N.Y. : 2000). 47: 815-24. PMID 19882671 DOI: 10.1002/Dvg.20572  0.441
2009 Yamagata K, Fujiyama S, Ito S, Ueda T, Murata T, Naitou M, Takeyama K, Minami Y, O'Malley BW, Kato S. Maturation of microRNA is hormonally regulated by a nuclear receptor. Molecular Cell. 36: 340-7. PMID 19854141 DOI: 10.1016/J.Molcel.2009.08.017  0.35
2009 Feng Q, He B, Jung SY, Song Y, Qin J, Tsai SY, Tsai MJ, O'Malley BW. Biochemical control of CARM1 enzymatic activity by phosphorylation. The Journal of Biological Chemistry. 284: 36167-74. PMID 19843527 DOI: 10.1074/Jbc.M109.065524  0.347
2009 Xu J, Wu RC, O'Malley BW. Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family. Nature Reviews. Cancer. 9: 615-30. PMID 19701241 DOI: 10.1038/Nrc2695  0.386
2009 Mödder UI, Monroe DG, Fraser DG, Spelsberg TC, Rosen CJ, Géhin M, Chambon P, O'Malley BW, Khosla S. Skeletal consequences of deletion of steroid receptor coactivator-2/transcription intermediary factor-2. The Journal of Biological Chemistry. 284: 18767-77. PMID 19423703 DOI: 10.1074/Jbc.M109.000836  0.351
2009 McKenna NJ, Cooney AJ, DeMayo FJ, Downes M, Glass CK, Lanz RB, Lazar MA, Mangelsdorf DJ, Moore DD, Qin J, Steffen DL, Tsai MJ, Tsai SY, Yu R, Margolis RN, et al. Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Molecular Endocrinology (Baltimore, Md.). 23: 740-6. PMID 19423650 DOI: 10.1210/Me.2009-0135  0.344
2009 Bochkis IM, Schug J, Rubins NE, Chopra AR, O'Malley BW, Kaestner KH. Foxa2-dependent hepatic gene regulatory networks depend on physiological state. Physiological Genomics. 38: 186-95. PMID 19417011 DOI: 10.1152/Physiolgenomics.90376.2008  0.306
2009 Stanisić V, Malovannaya A, Qin J, Lonard DM, O'Malley BW. OTU Domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) deubiquitinates estrogen receptor (ER) alpha and affects ERalpha transcriptional activity. The Journal of Biological Chemistry. 284: 16135-45. PMID 19383985 DOI: 10.1074/Jbc.M109.007484  0.439
2009 O'Malley BW. The "fourth dimension" of gene transcription. Molecular Endocrinology (Baltimore, Md.). 23: 587-9. PMID 19221049 DOI: 10.1210/Me.2009-0015  0.329
2009 Wang S, Yuan Y, Liao L, Kuang SQ, Tien JC, O'Malley BW, Xu J. Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation. Proceedings of the National Academy of Sciences of the United States of America. 106: 151-6. PMID 19109434 DOI: 10.1073/Pnas.0808703105  0.348
2009 Han SJ, Lonard DM, O'Malley BW. Multi-modulation of nuclear receptor coactivators through posttranslational modifications. Trends in Endocrinology and Metabolism: Tem. 20: 8-15. PMID 19019695 DOI: 10.1016/j.tem.2008.10.001  0.317
2009 Mani SK, O'Malley BW. Mechanism of Progesterone Receptor Action in the Brain Hormones, Brain and Behavior. 45: 1467-1504. DOI: 10.1016/B978-008088783-8.00045-0  0.46
2008 Li C, Liang YY, Feng XH, Tsai SY, Tsai MJ, O'Malley BW. Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. Molecular Cell. 31: 835-49. PMID 18922467 DOI: 10.1016/J.Molcel.2008.07.019  0.418
2008 O'Malley B. The Year in Basic Science: nuclear receptors and coregulators. Molecular Endocrinology (Baltimore, Md.). 22: 2751-8. PMID 18845672 DOI: 10.1210/Me.2008-0297  0.351
2008 Kang YK, Schiff R, Ko L, Wang T, Tsai SY, Tsai MJ, O'Malley BW. Dual roles for coactivator activator and its counterbalancing isoform coactivator modulator in human kidney cell tumorigenesis. Cancer Research. 68: 7887-96. PMID 18829545 DOI: 10.1158/0008-5472.Can-08-1734  0.612
2008 O'Malley BW, McKenna NJ. Coactivators and corepressors: what's in a name? Molecular Endocrinology (Baltimore, Md.). 22: 2213-4. PMID 18701638 DOI: 10.1210/Me.2008-0201  0.366
2008 Fereshteh MP, Tilli MT, Kim SE, Xu J, O'Malley BW, Wellstein A, Furth PA, Riegel AT. The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice. Cancer Research. 68: 3697-706. PMID 18483252 DOI: 10.1158/0008-5472.Can-07-6702  0.382
2008 Lonard DM, O'Malley BW. Gene transcription: two worlds merged. Nature. 452: 946-7. PMID 18432236 DOI: 10.1038/452946A  0.33
2008 Yi P, Feng Q, Amazit L, Lonard DM, Tsai SY, Tsai MJ, O'Malley BW. Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1. Molecular Cell. 29: 465-76. PMID 18313384 DOI: 10.1016/J.Molcel.2007.12.030  0.38
2008 He B, Feng Q, Mukherjee A, Lonard DM, DeMayo FJ, Katzenellenbogen BS, Lydon JP, O'Malley BW. A repressive role for prohibitin in estrogen signaling. Molecular Endocrinology (Baltimore, Md.). 22: 344-60. PMID 17932104 DOI: 10.1210/Me.2007-0400  0.4
2007 Mukherjee A, Amato P, Craig-Allred D, DeMayo FJ, O'Malley BW, Lydon JP. Steroid receptor coactivator 2: an essential coregulator of progestin-induced uterine and mammary morphogenesis. Ernst Schering Foundation Symposium Proceedings. 55-76. PMID 18540568  0.322
2007 Loehberg CR, Thompson T, Kastan MB, Maclean KH, Edwards DG, Kittrell FS, Medina D, Conneely OM, O'Malley BW. Ataxia telangiectasia-mutated and p53 are potential mediators of chloroquine-induced resistance to mammary carcinogenesis. Cancer Research. 67: 12026-33. PMID 18089834 DOI: 10.1158/0008-5472.Can-07-3058  0.343
2007 Jordan VC, O'Malley BW. Selective estrogen-receptor modulators and antihormonal resistance in breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 5815-24. PMID 17893378 DOI: 10.1200/Jco.2007.11.3886  0.376
2007 Amazit L, Pasini L, Szafran AT, Berno V, Wu RC, Mielke M, Jones ED, Mancini MG, Hinojos CA, O'Malley BW, Mancini MA. Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation. Molecular and Cellular Biology. 27: 6913-32. PMID 17646391 DOI: 10.1128/Mcb.01695-06  0.456
2007 Lonard DM, Lanz RB, O'Malley BW. Nuclear receptor coregulators and human disease. Endocrine Reviews. 28: 575-87. PMID 17609497 DOI: 10.1210/er.2007-0012  0.318
2007 Li X, Amazit L, Long W, Lonard DM, Monaco JJ, O'Malley BW. Ubiquitin- and ATP-independent proteolytic turnover of p21 by the REGgamma-proteasome pathway. Molecular Cell. 26: 831-42. PMID 17588518 DOI: 10.1016/J.Molcel.2007.05.028  0.365
2007 Wu RC, Feng Q, Lonard DM, O'Malley BW. SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock. Cell. 129: 1125-40. PMID 17574025 DOI: 10.1016/J.Cell.2007.04.039  0.373
2007 Jeong JW, Lee KY, Han SJ, Aronow BJ, Lydon JP, O'Malley BW, DeMayo FJ. The p160 steroid receptor coactivator 2, SRC-2, regulates murine endometrial function and regulates progesterone-independent and -dependent gene expression. Endocrinology. 148: 4238-50. PMID 17556502 DOI: 10.1210/en.2007-0122  0.31
2007 Meng Q, Rayala SK, Gururaj AE, Talukder AH, O'Malley BW, Kumar R. Signaling-dependent and coordinated regulation of transcription, splicing, and translation resides in a single coregulator, PCBP1. Proceedings of the National Academy of Sciences of the United States of America. 104: 5866-71. PMID 17389360 DOI: 10.1073/Pnas.0701065104  0.392
2007 Yu C, York B, Wang S, Feng Q, Xu J, O'Malley BW. An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response. Molecular Cell. 25: 765-78. PMID 17349961 DOI: 10.1016/J.Molcel.2007.01.025  0.312
2007 Han SJ, Tsai SY, Tsai MJ, O'Malley BW. Distinct temporal and spatial activities of RU486 on progesterone receptor function in reproductive organs of ovariectomized mice. Endocrinology. 148: 2471-86. PMID 17303655 DOI: 10.1210/en.2006-1561  0.305
2007 Li C, Wu RC, Amazit L, Tsai SY, Tsai MJ, O'Malley BW. Specific amino acid residues in the basic helix-loop-helix domain of SRC-3 are essential for its nuclear localization and proteasome-dependent turnover. Molecular and Cellular Biology. 27: 1296-308. PMID 17158932 DOI: 10.1128/Mcb.00336-06  0.348
2007 Han SJ, DeMayo F, O'Malley B. ROLES OF STEROID RECEPTOR COACTIVATORS IN CATEGORICAL REPROGRAMMING DURING cAMP/PKA MEDIATED DECIDUALIZATION IN HUMAN ENDOMETRIAL STROMAL CELLS Biology of Reproduction. 77: 120-120. DOI: 10.1093/Biolreprod/77.S1.120B  0.399
2006 Louet JF, Coste A, Amazit L, Tannour-Louet M, Wu RC, Tsai SY, Tsai MJ, Auwerx J, O'Malley BW. Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program. Proceedings of the National Academy of Sciences of the United States of America. 103: 17868-73. PMID 17098861 DOI: 10.1073/Pnas.0608711103  0.439
2006 Mussi P, Liao L, Park SE, Ciana P, Maggi A, Katzenellenbogen BS, Xu J, O'Malley BW. Haploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary gland. Proceedings of the National Academy of Sciences of the United States of America. 103: 16716-21. PMID 17065319 DOI: 10.1073/Pnas.0607768103  0.438
2006 Mukherjee A, Amato P, Allred DC, Fernandez-Valdivia R, Nguyen J, O'Malley BW, DeMayo FJ, Lydon JP. Steroid receptor coactivator 2 is essential for progesterone-dependent uterine function and mammary morphogenesis: insights from the mouse--implications for the human. The Journal of Steroid Biochemistry and Molecular Biology. 102: 22-31. PMID 17045797 DOI: 10.1016/j.jsbmb.2006.09.007  0.332
2006 Feng Q, Yi P, Wong J, O'Malley BW. Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly. Molecular and Cellular Biology. 26: 7846-57. PMID 16923966 DOI: 10.1128/Mcb.00568-06  0.419
2006 Mussi P, Yu C, O'Malley BW, Xu J. Stimulation of steroid receptor coactivator-3 (SRC-3) gene overexpression by a positive regulatory loop of E2F1 and SRC-3. Molecular Endocrinology (Baltimore, Md.). 20: 3105-19. PMID 16916939 DOI: 10.1210/me.2005-0522  0.336
2006 Mukherjee A, Soyal SM, Fernandez-Valdivia R, Gehin M, Chambon P, Demayo FJ, Lydon JP, O'Malley BW. Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse. Molecular and Cellular Biology. 26: 6571-83. PMID 16914740 DOI: 10.1128/Mcb.00654-06  0.446
2006 Han SJ, Jung SY, Malovannaya A, Kim T, Lanz RB, Qin J, O'Malley BW. A scoring system for the follow up study of nuclear receptor coactivator complexes. Nuclear Receptor Signaling. 4: e014. PMID 16862220 DOI: 10.1621/Nrs.04014  0.391
2006 Dhananjayan SC, Ramamoorthy S, Khan OY, Ismail A, Sun J, Slingerland J, O'Malley BW, Nawaz Z. WW domain binding protein-2, an E6-associated protein interacting protein, acts as a coactivator of estrogen and progesterone receptors. Molecular Endocrinology (Baltimore, Md.). 20: 2343-54. PMID 16772533 DOI: 10.1210/Me.2005-0533  0.44
2006 Hatchell EC, Colley SM, Beveridge DJ, Epis MR, Stuart LM, Giles KM, Redfern AD, Miles LE, Barker A, MacDonald LM, Arthur PG, Lui JC, Golding JL, McCulloch RK, Metcalf CB, et al. SLIRP, a small SRA binding protein, is a nuclear receptor corepressor. Molecular Cell. 22: 657-68. PMID 16762838 DOI: 10.1016/j.molcel.2006.05.024  0.303
2006 Lonard DM, O'Malley BW. The expanding cosmos of nuclear receptor coactivators. Cell. 125: 411-4. PMID 16678083 DOI: 10.1016/j.cell.2006.04.021  0.334
2006 Coste A, Antal MC, Chan S, Kastner P, Mark M, O'Malley BW, Auwerx J. Absence of the steroid receptor coactivator-3 induces B-cell lymphoma. The Embo Journal. 25: 2453-64. PMID 16675958 DOI: 10.1038/Sj.Emboj.7601106  0.321
2006 Li X, Lonard DM, Jung SY, Malovannaya A, Feng Q, Qin J, Tsai SY, Tsai MJ, O'Malley BW. The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell. 124: 381-92. PMID 16439211 DOI: 10.1016/J.Cell.2005.11.037  0.438
2006 Han SJ, DeMayo FJ, Xu J, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor. Molecular Endocrinology (Baltimore, Md.). 20: 45-55. PMID 16141356 DOI: 10.1210/me.2005-0310  0.306
2005 Yi P, Wu RC, Sandquist J, Wong J, Tsai SY, Tsai MJ, Means AR, O'Malley BW. Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1). Molecular and Cellular Biology. 25: 9687-99. PMID 16227615 DOI: 10.1128/Mcb.25.21.9687-9699.2005  0.5
2005 Kuang SQ, Liao L, Wang S, Medina D, O'Malley BW, Xu J. Mice lacking the amplified in breast cancer 1/steroid receptor coactivator-3 are resistant to chemical carcinogen-induced mammary tumorigenesis. Cancer Research. 65: 7993-8002. PMID 16140972 DOI: 10.1158/0008-5472.Can-05-1179  0.385
2005 Zheng FF, Wu RC, Smith CL, O'Malley BW. Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor. Molecular and Cellular Biology. 25: 8273-84. PMID 16135815 DOI: 10.1128/Mcb.25.18.8273-8284.2005  0.406
2005 Han SJ, Jeong J, Demayo FJ, Xu J, Tsai SY, Tsai MJ, O'Malley BW. Dynamic cell type specificity of SRC-1 coactivator in modulating uterine progesterone receptor function in mice. Molecular and Cellular Biology. 25: 8150-65. PMID 16135805 DOI: 10.1128/Mcb.25.18.8150-8165.2005  0.493
2005 McKenna NJ, O'Malley BW. Teaching resources. An interactive course in nuclear receptor signaling: concepts and models. Science's Stke : Signal Transduction Knowledge Environment. 2005: tr22. PMID 16131668 DOI: 10.1126/Stke.2992005Tr22  0.348
2005 Jung SY, Malovannaya A, Wei J, O'Malley BW, Qin J. Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes. Molecular Endocrinology (Baltimore, Md.). 19: 2451-65. PMID 16051665 DOI: 10.1210/me.2004-0476  0.316
2005 Ye X, Han SJ, Tsai SY, DeMayo FJ, Xu J, Tsai MJ, O'Malley BW. Roles of steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF) 2 in androgen receptor activity in mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 9487-92. PMID 15983373 DOI: 10.1073/Pnas.0503577102  0.391
2005 Apostolakis EM, Riherd DN, O'Malley BW. PAC1 receptors mediate pituitary adenylate cyclase-activating polypeptide- and progesterone-facilitated receptivity in female rats. Molecular Endocrinology (Baltimore, Md.). 19: 2798-811. PMID 15976009 DOI: 10.1210/me.2004-0387  0.314
2005 Auboeuf D, Dowhan DH, Dutertre M, Martin N, Berget SM, O'Malley BW. A subset of nuclear receptor coregulators act as coupling proteins during synthesis and maturation of RNA transcripts. Molecular and Cellular Biology. 25: 5307-16. PMID 15964789 DOI: 10.1128/Mcb.25.13.5307-5316.2005  0.394
2005 Masuhiro Y, Mezaki Y, Sakari M, Takeyama K, Yoshida T, Inoue K, Yanagisawa J, Hanazawa S, O'malley BW, Kato S. Splicing potentiation by growth factor signals via estrogen receptor phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 102: 8126-31. PMID 15919818 DOI: 10.1073/Pnas.0503197102  0.402
2005 Wu RC, Smith CL, O'Malley BW. Transcriptional regulation by steroid receptor coactivator phosphorylation. Endocrine Reviews. 26: 393-9. PMID 15814849 DOI: 10.1210/er.2004-0018  0.356
2005 Park KJ, Krishnan V, O'Malley BW, Yamamoto Y, Gaynor RB. Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation. Molecular Cell. 18: 71-82. PMID 15808510 DOI: 10.1016/j.molcel.2005.03.006  0.364
2005 Lonard DM, O'Malley BW. Expanding functional diversity of the coactivators. Trends in Biochemical Sciences. 30: 126-32. PMID 15752984 DOI: 10.1016/J.Tibs.2005.01.001  0.403
2005 Park SE, Xu J, Frolova A, Liao L, O'Malley BW, Katzenellenbogen BS. Genetic deletion of the repressor of estrogen receptor activity (REA) enhances the response to estrogen in target tissues in vivo. Molecular and Cellular Biology. 25: 1989-99. PMID 15713652 DOI: 10.1128/Mcb.25.5.1989-1999.2005  0.44
2005 Dowhan DH, Hong EP, Auboeuf D, Dennis AP, Wilson MM, Berget SM, O'Malley BW. Steroid hormone receptor coactivation and alternative RNA splicing by U2AF65-related proteins CAPERalpha and CAPERbeta. Molecular Cell. 17: 429-39. PMID 15694343 DOI: 10.1016/J.Molcel.2004.12.025  0.455
2005 Labhart P, Karmakar S, Salicru EM, Egan BS, Alexiadis V, O'Malley BW, Smith CL. Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator. Proceedings of the National Academy of Sciences of the United States of America. 102: 1339-44. PMID 15677324 DOI: 10.1073/Pnas.0409578102  0.443
2005 Reddy DS, O'Malley BW, Rogawski MA. Anxiolytic activity of progesterone in progesterone receptor knockout mice. Neuropharmacology. 48: 14-24. PMID 15617723 DOI: 10.1016/J.Neuropharm.2004.09.002  0.407
2005 Wu HY, Hamamori Y, Xu J, Chang SC, Saluna T, Chang MF, O'Malley BW, Kedes L. Nuclear hormone receptor coregulator GRIP1 suppresses, whereas SRC1A and p/CIP coactivate, by domain-specific binding of MyoD. The Journal of Biological Chemistry. 280: 3129-37. PMID 15563453 DOI: 10.1074/Jbc.M412560200  0.378
2004 O'Malley BW. Results of a search for the mechanisms of steroid receptor regulation of gene expression. Annals of the New York Academy of Sciences. 1038: 80-7. PMID 15838100 DOI: 10.1196/Annals.1315.014  0.461
2004 Nishihara E, O'Malley BW, Xu J. Nuclear receptor coregulators are new players in nervous system development and function. Molecular Neurobiology. 30: 307-25. PMID 15655254 DOI: 10.1385/MN:30:3:307  0.32
2004 Li X, Lonard DM, O'Malley BW. A contemporary understanding of progesterone receptor function. Mechanisms of Ageing and Development. 125: 669-78. PMID 15541762 DOI: 10.1016/j.mad.2004.04.007  0.316
2004 Wu RC, Qin J, Yi P, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Molecular Cell. 15: 937-49. PMID 15383283 DOI: 10.1016/J.Molcel.2004.08.019  0.373
2004 Verma S, Ismail A, Gao X, Fu G, Li X, O'Malley BW, Nawaz Z. The ubiquitin-conjugating enzyme UBCH7 acts as a coactivator for steroid hormone receptors. Molecular and Cellular Biology. 24: 8716-26. PMID 15367689 DOI: 10.1128/Mcb.24.19.8716-8726.2004  0.471
2004 Mark M, Yoshida-Komiya H, Gehin M, Liao L, Tsai MJ, O'Malley BW, Chambon P, Xu J. Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction. Proceedings of the National Academy of Sciences of the United States of America. 101: 4453-8. PMID 15070739 DOI: 10.1073/Pnas.0400234101  0.333
2004 Kuang SQ, Liao L, Zhang H, Lee AV, O'Malley BW, Xu J. AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-ras-induced breast cancer initiation and progression in mice. Cancer Research. 64: 1875-85. PMID 14996752 DOI: 10.1158/0008-5472.Can-03-3745  0.327
2004 Auboeuf D, Dowhan DH, Kang YK, Larkin K, Lee JW, Berget SM, O'Malley BW. Differential recruitment of nuclear receptor coactivators may determine alternative RNA splice site choice in target genes. Proceedings of the National Academy of Sciences of the United States of America. 101: 2270-4. PMID 14982999 DOI: 10.1073/Pnas.0308133100  0.65
2004 Reddy DS, Castaneda DC, O'Malley BW, Rogawski MA. Anticonvulsant activity of progesterone and neurosteroids in progesterone receptor knockout mice. The Journal of Pharmacology and Experimental Therapeutics. 310: 230-9. PMID 14982969 DOI: 10.1124/Jpet.104.065268  0.362
2004 Smith CL, O'Malley BW. Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocrine Reviews. 25: 45-71. PMID 14769827 DOI: 10.1210/er.2003-0023  0.344
2004 Mollenhauer J, Helmke B, Medina D, Bergmann G, Gassler N, Müller H, Lyer S, Diedrichs L, Renner M, Wittig R, Blaich S, Hamann U, Madsen J, Holmskov U, Bikker F, et al. Carcinogen inducibility in vivo and down-regulation of DMBT1 during breast carcinogenesis. Genes, Chromosomes & Cancer. 39: 185-94. PMID 14732920 DOI: 10.1002/Gcc.10309  0.309
2004 Auboeuf D, Dowhan DH, Li X, Larkin K, Ko L, Berget SM, O'Malley BW. CoAA, a nuclear receptor coactivator protein at the interface of transcriptional coactivation and RNA splicing. Molecular and Cellular Biology. 24: 442-53. PMID 14673176 DOI: 10.1128/Mcb.24.1.442-453.2004  0.407
2004 Lonard DM, Tsai SY, O'Malley BW. Selective estrogen receptor modulators 4-hydroxytamoxifen and raloxifene impact the stability and function of SRC-1 and SRC-3 coactivator proteins. Molecular and Cellular Biology. 24: 14-24. PMID 14673139 DOI: 10.1128/Mcb.24.1.14-24.2004  0.456
2004 Nawaz Z, O'Malley BW. Urban renewal in the nucleus: is protein turnover by proteasomes absolutely required for nuclear receptor-regulated transcription? Molecular Endocrinology (Baltimore, Md.). 18: 493-9. PMID 14673136 DOI: 10.1210/Me.2003-0388  0.352
2003 O'Malley BW. Sequentiality and processivity of nuclear receptor coregulators in regulation of target gene expression. Nuclear Receptor Signaling. 1: e010. PMID 16604182 DOI: 10.1621/Nrs.01010  0.414
2003 Lanz RB, Chua SS, Barron N, Söder BM, DeMayo F, O'Malley BW. Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo. Molecular and Cellular Biology. 23: 7163-76. PMID 14517287 DOI: 10.1128/Mcb.23.20.7163-7176.2003  0.454
2003 Lan ZJ, Gu P, Xu X, Jackson KJ, DeMayo FJ, O'Malley BW, Cooney AJ. GCNF-dependent repression of BMP-15 and GDF-9 mediates gamete regulation of female fertility. The Embo Journal. 22: 4070-81. PMID 12912906 DOI: 10.1093/Emboj/Cdg405  0.352
2003 Li X, O'Malley BW. Unfolding the action of progesterone receptors. The Journal of Biological Chemistry. 278: 39261-4. PMID 12893816 DOI: 10.1074/Jbc.R300024200  0.381
2003 Li X, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Molecular and Cellular Biology. 23: 3763-73. PMID 12748280 DOI: 10.1128/Mcb.23.11.3763-3773.2003  0.462
2003 Cheskis BJ, McKenna NJ, Wong CW, Wong J, Komm B, Lyttle CR, O'Malley BW. Hierarchical affinities and a bipartite interaction model for estrogen receptor isoforms and full-length steroid receptor coactivator (SRC/p160) family members. The Journal of Biological Chemistry. 278: 13271-7. PMID 12540843 DOI: 10.1074/Jbc.M211031200  0.389
2003 Nishihara E, Yoshida-Komiya H, Chan CS, Liao L, Davis RL, O'Malley BW, Xu J. SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar Purkinje cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 213-22. PMID 12514218 DOI: 10.1523/Jneurosci.23-01-00213.2003  0.35
2003 Apostolakis EM, Ramamurphy M, Zhou D, Oñate S, O'Malley BW. Acute disruption of select steroid receptor coactivators prevents reproductive behavior in rats and unmasks genetic adaptation in knockout mice. Molecular Endocrinology (Baltimore, Md.). 16: 1511-23. PMID 12089347 DOI: 10.1210/MEND.16.7.0877  0.317
2002 Liao L, Kuang SQ, Yuan Y, Gonzalez SM, O'Malley BW, Xu J. Molecular structure and biological function of the cancer-amplified nuclear receptor coactivator SRC-3/AIB1. The Journal of Steroid Biochemistry and Molecular Biology. 83: 3-14. PMID 12650696 DOI: 10.1016/S0960-0760(02)00254-6  0.477
2002 Lanz RB, Razani B, Goldberg AD, O'Malley BW. Distinct RNA motifs are important for coactivation of steroid hormone receptors by steroid receptor RNA activator (SRA). Proceedings of the National Academy of Sciences of the United States of America. 99: 16081-6. PMID 12444263 DOI: 10.1073/Pnas.192571399  0.373
2002 Auboeuf D, Hönig A, Berget SM, O'Malley BW. Coordinate regulation of transcription and splicing by steroid receptor coregulators. Science (New York, N.Y.). 298: 416-9. PMID 12376702 DOI: 10.1126/Science.1073734  0.435
2002 Hönig A, Auboeuf D, Parker MM, O'Malley BW, Berget SM. Regulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72. Molecular and Cellular Biology. 22: 5698-707. PMID 12138182 DOI: 10.1128/Mcb.22.16.5698-5707.2002  0.309
2002 McKenna NJ, O'Malley BW. Minireview: nuclear receptor coactivators--an update. Endocrinology. 143: 2461-5. PMID 12072374 DOI: 10.1210/endo.143.7.8892  0.327
2002 Cao T, Tsai SY, O'Malley BW, Wang XJ, Roop DR. The epidermis as a bioreactor: topically regulated cutaneous delivery into the circulation. Human Gene Therapy. 13: 1075-80. PMID 12067440 DOI: 10.1089/104303402753812476  0.333
2002 Liu Z, Auboeuf D, Wong J, Chen JD, Tsai SY, Tsai MJ, O'Malley BW. Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486. Proceedings of the National Academy of Sciences of the United States of America. 99: 7940-4. PMID 12048256 DOI: 10.1073/Pnas.122225699  0.467
2002 Conneely OM, Mulac-Jericevic B, DeMayo F, Lydon JP, O'Malley BW. Reproductive functions of progesterone receptors. Recent Progress in Hormone Research. 57: 339-55. PMID 12017551 DOI: 10.1210/Rp.57.1.339  0.422
2002 Wu RC, Qin J, Hashimoto Y, Wong J, Xu J, Tsai SY, Tsai MJ, O'Malley BW. Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Molecular and Cellular Biology. 22: 3549-61. PMID 11971985 DOI: 10.1128/Mcb.22.10.3549-3561.2002  0.383
2002 McKenna NJ, O'Malley BW. Combinatorial control of gene expression by nuclear receptors and coregulators. Cell. 108: 465-74. PMID 11909518 DOI: 10.1016/S0092-8674(02)00641-4  0.319
2002 Ye X, Schillinger K, Burcin MM, Tsai SV, O'Malley BW. Ligand-inducible transgene regulation for gene therapy Methods in Enzymology. 346: 551-561. PMID 11883090 DOI: 10.1016/S0076-6879(02)46076-4  0.364
2002 Markaverich B, Mani S, Alejandro MA, Mitchell A, Markaverich D, Brown T, Velez-Trippe C, Murchison C, O'Malley B, Faith R. A novel endocrine-disrupting agent in corn with mitogenic activity in human breast and prostatic cancer cells. Environmental Health Perspectives. 110: 169-77. PMID 11836146 DOI: 10.1289/Ehp.02110169  0.35
2002 Cavarretta ITR, Mukopadhyay R, Lonard DM, Cowsert LM, Bennett CF, O'Malley BW, Smith CL. Reduction of coactivator expression by antisense oligodeoxynucleotides inhibits ERα transcriptional activity and MCF-7 proliferation Molecular Endocrinology. 16: 253-270. PMID 11818499 DOI: 10.1210/MEND.16.2.0770  0.374
2002 McKenna NJ, O'Malley BW. Nuclear receptors, coregulators, ligands, and selective receptor modulators: making sense of the patchwork quilt. Annals of the New York Academy of Sciences. 949: 3-5. PMID 11795367 DOI: 10.1111/J.1749-6632.2001.Tb03997.X  0.456
2001 Liu Z, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Sequential recruitment of steroid receptor coactivator-1 (SRC-1) and p300 enhances progesterone receptor-dependent initiation and reinitiation of transcription from chromatin. Proceedings of the National Academy of Sciences of the United States of America. 98: 12426-31. PMID 11606780 DOI: 10.1073/Pnas.231474798  0.436
2001 Sivaraman L, Conneely OM, Medina D, O'Malley BW. p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 98: 12379-84. PMID 11606748 DOI: 10.1073/Pnas.221459098  0.344
2001 Stenoien DL, Nye AC, Mancini MG, Patel K, Dutertre M, O'Malley BW, Smith CL, Belmont AS, Mancini MA. Ligand-mediated assembly and real-time cellular dynamics of estrogen receptor alpha-coactivator complexes in living cells. Molecular and Cellular Biology. 21: 4404-12. PMID 11390668 DOI: 10.1128/Mcb.21.13.4404-4412.2001  0.408
2001 McKenna NJ, O'Malley BW. From ligand to response: generating diversity in nuclear receptor coregulator function. The Journal of Steroid Biochemistry and Molecular Biology. 74: 351-6. PMID 11162944 DOI: 10.1016/S0960-0760(00)00112-6  0.441
2001 Mani SK, Mitchell A, O'Malley BW. Progesterone receptor and dopamine receptors are required in Delta 9-tetrahydrocannabinol modulation of sexual receptivity in female rats. Proceedings of the National Academy of Sciences of the United States of America. 98: 1249-54. PMID 11158625 DOI: 10.1073/Pnas.031563998  0.347
2001 Stenoien DL, Patel K, Mancini MG, Dutertre M, Smith CL, O'Malley BW, Mancini MA. FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent. Nature Cell Biology. 3: 15-23. PMID 11146621 DOI: 10.1038/35050515  0.339
2001 Chung AC, Katz D, Pereira FA, Jackson KJ, DeMayo FJ, Cooney AJ, O'Malley BW. Loss of orphan receptor germ cell nuclear factor function results in ectopic development of the tail bud and a novel posterior truncation. Molecular and Cellular Biology. 21: 663-77. PMID 11134352 DOI: 10.1128/Mcb.21.2.663-677.2001  0.342
2001 Rowan BG, O'Malley BW. Progesterone receptor coactivators. Steroids. 65: 545-9. PMID 11108858 DOI: 10.1016/S0039-128X(00)00112-4  0.361
2000 Robker RL, Russell DL, Yoshioka S, Sharma SC, Lydon JP, O'Malley BW, Espey LL, Richards JS. Ovulation: a multi-gene, multi-step process. Steroids. 65: 559-70. PMID 11108860 DOI: 10.1016/S0039-128X(00)00114-8  0.336
2000 Rowan BG, Garrison N, Weigel NL, O'Malley BW. 8-Bromo-cyclic AMP induces phosphorylation of two sites in SRC-1 that facilitate ligand-independent activation of the chicken progesterone receptor and are critical for functional cooperation between SRC-1 and CREB binding protein. Molecular and Cellular Biology. 20: 8720-30. PMID 11073973 DOI: 10.1128/Mcb.20.23.8720-8730.2000  0.387
2000 Sivaraman L, Nawaz Z, Medina D, Conneely OM, O'Malley BW. The dual function steroid receptor coactivator/ubiquitin protein-ligase integrator E6-AP is overexpressed in mouse mammary tumorigenesis Breast Cancer Research and Treatment. 62: 185-195. PMID 11072783 DOI: 10.1023/A:1006410111706  0.411
2000 Abruzzese RV, Godin D, Mehta V, Perrard JL, French M, Nelson W, Howell G, Coleman M, O'Malley BW, Nordstrom JL. Ligand-dependent regulation of vascular endothelial growth factor and erythropoietin expression by a plasmid-based autoinducible GeneSwitch system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 2: 276-87. PMID 10985958 DOI: 10.1006/Mthe.2000.0115  0.362
2000 McKenna NJ, O'Malley BW. An issue of tissues: divining the split personalities of selective estrogen receptor modulators. Nature Medicine. 6: 960-2. PMID 10973303 DOI: 10.1038/79637  0.371
2000 Humphreys RC, Lydon JP, O'Malley BW, Rosen JM. Use of PRKO mice to study the role of progesterone in mammary gland development. Journal of Mammary Gland Biology and Neoplasia. 2: 343-54. PMID 10935022 DOI: 10.1023/A:1026343212187  0.338
2000 Lonard DM, Nawaz Z, Smith CL, O'Malley BW. The 26S proteasome is required for estrogen receptor-α and coactivator turnover and for efficient estrogen receptor-α transactivation Molecular Cell. 5: 939-948. PMID 10911988 DOI: 10.1016/S1097-2765(00)80259-2  0.334
2000 Apostolakis EM, Garai J, Lohmann JE, Clark JH, O'Malley BW. Epidermal growth factor activates reproductive behavior independent of ovarian steroids in female rodents. Molecular Endocrinology (Baltimore, Md.). 14: 1086-98. PMID 10894157 DOI: 10.1210/mend.14.7.0490  0.326
2000 Xu J, Liao L, Ning G, Yoshida-Komiya H, Deng C, O'Malley BW. The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development. Proceedings of the National Academy of Sciences of the United States of America. 97: 6379-84. PMID 10823921 DOI: 10.1073/Pnas.120166297  0.413
2000 Li J, O'Malley BW, Wong J. p300 requires its histone acetyltransferase activity and SRC-1 interaction domain to facilitate thyroid hormone receptor activation in chromatin. Molecular and Cellular Biology. 20: 2031-42. PMID 10688650 DOI: 10.1128/Mcb.20.6.2031-2042.2000  0.393
2000 Mani SK, Fienberg AA, O'Callaghan JP, Snyder GL, Allen PB, Dash PK, Moore AN, Mitchell AJ, Bibb J, Greengard P, O'Malley BW. Requirement for DARPP-32 in progesterone-facilitated sexual receptivity in female rats and mice. Science (New York, N.Y.). 287: 1053-6. PMID 10669419 DOI: 10.1126/Science.287.5455.1053  0.315
2000 Rowan BG, Weigel NL, O'Malley BW. Phosphorylation of steroid receptor coactivator-1. Identification of the phosphorylation sites and phosphorylation through the mitogen-activated protein kinase pathway. The Journal of Biological Chemistry. 275: 4475-83. PMID 10660621 DOI: 10.1074/Jbc.275.6.4475  0.396
2000 Zhou D, Apostolakis EM, O'Malley BW. Distribution of D(5) dopamine receptor mRNA in rat ventromedial hypothalamic nucleus. Biochemical and Biophysical Research Communications. 266: 556-9. PMID 10600540 DOI: 10.1006/Bbrc.1999.1851  0.339
2000 Smith CL, O'Malley BW. Evolving concepts of selective estrogen receptor action: from basic science to clinical applications. Trends in Endocrinology and Metabolism: Tem. 10: 299-300. PMID 10481159 DOI: 10.1016/S1043-2760(99)00183-6  0.328
1999 Wang Y, Tsai SY, O'Malley BW. An antiprogestin regulable gene switch for induction of gene expression in vivo. Advances in Pharmacology (San Diego, Calif.). 47: 343-55. PMID 10582091 DOI: 10.1016/S1054-3589(08)60116-7  0.319
1999 Liu Z, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor coactivator-1 (SRC-1) enhances ligand-dependent and receptor-dependent cell-free transcription of chromatin. Proceedings of the National Academy of Sciences of the United States of America. 96: 9485-90. PMID 10449719 DOI: 10.1073/PNAS.96.17.9485  0.324
1999 Wang Y, Tsai SY, O'Malley BW. Antiprogestin regulable gene switch for induction of gene expression in vivo. Methods in Enzymology. 306: 281-94. PMID 10432460 DOI: 10.1016/S0076-6879(99)06018-8  0.398
1999 McKenna NJ, Xu J, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. Nuclear receptor coactivators: Multiple enzymes, multiple complexes, multiple functions Journal of Steroid Biochemistry and Molecular Biology. 69: 3-12. PMID 10418975 DOI: 10.1016/S0960-0760(98)00144-7  0.471
1999 Abruzzese RV, Godin D, Burcin M, Mehta V, French M, Li Y, O'Malley BW, Nordstrom JL. Ligand-dependent regulation of plasmid-based transgene expression in vivo. Human Gene Therapy. 10: 1499-507. PMID 10395375 DOI: 10.1089/10430349950017833  0.337
1999 McKenna NJ, Lanz RB, O'Malley BW. Nuclear receptor coregulators: cellular and molecular biology. Endocrine Reviews. 20: 321-44. PMID 10368774 DOI: 10.1210/EDRV.20.3.0366  0.336
1999 Tibbetts TA, Conneely OM, O'Malley BW. Progesterone via its receptor antagonizes the pro-inflammatory activity of estrogen in the mouse uterus. Biology of Reproduction. 60: 1158-65. PMID 10208978 DOI: 10.1095/Biolreprod60.5.1158  0.372
1999 Lanz RB, McKenna NJ, Onate SA, Albrecht U, Wong J, Tsai SY, Tsai MJ, O'Malley BW. A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Cell. 97: 17-27. PMID 10199399 DOI: 10.1016/S0092-8674(00)80711-4  0.372
1999 Burcin MM, Schiedner G, Kochanek S, Tsai SY, O'Malley BW. Adenovirus-mediated regulable target gene expression in vivo Proceedings of the National Academy of Sciences of the United States of America. 96: 355-360. PMID 9892637 DOI: 10.1073/pnas.96.2.355  0.303
1999 Nawaz Z, Lonard DM, Smith CL, Lev-Lehman E, Tsai SY, Tsai MJ, O'Malley BW. The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily Molecular and Cellular Biology. 19: 1182-1189. PMID 9891052 DOI: 10.1128/Mcb.19.2.1182  0.343
1998 Chua SS, Wang Y, DeMayo FJ, O'Malley BW, Tsai SY. A novel RU486 inducible system for the activation and repression of genes. Advanced Drug Delivery Reviews. 30: 23-31. PMID 10837599 DOI: 10.1016/S0169-409X(97)00104-X  0.399
1998 Phelps SM, Lydon JP, O'malley BW, Crews D. Regulation of male sexual behavior by progesterone receptor, sexual experience, and androgen. Hormones and Behavior. 34: 294-302. PMID 9878278 DOI: 10.1006/Hbeh.1998.1485  0.315
1998 Mckenna NJ, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. Distinct steady-state nuclear receptor coregulator complexes exist in vivo Proceedings of the National Academy of Sciences of the United States of America. 95: 11697-11702. PMID 9751728 DOI: 10.1073/Pnas.95.20.11697  0.442
1998 Onate SA, Boonyaratanakornkit V, Spencer TE, Tsai SY, Tsai MJ, Edwards DP, O'Malley BW. The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors. The Journal of Biological Chemistry. 273: 12101-8. PMID 9575154 DOI: 10.1074/Jbc.273.20.12101  0.33
1998 Xu J, Qiu Y, DeMayo FJ, Tsai SY, Tsai MJ, O'Malley BW. Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene. Science (New York, N.Y.). 279: 1922-5. PMID 9506940 DOI: 10.1126/SCIENCE.279.5358.1922  0.308
1997 Gangolli EA, Conneely OM, O'Malley BW. Neurotransmitters activate the human estrogen receptor in a neuroblastoma cell line. The Journal of Steroid Biochemistry and Molecular Biology. 61: 1-9. PMID 9328204 DOI: 10.1016/S0960-0760(97)00003-4  0.424
1997 Spencer TE, Jenster G, Burcin MM, Allis CD, Zhou J, Mizzen CA, McKenna NJ, Onate SA, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor coactivator-1 is a histone acetyltransferase Nature. 389: 194-198. PMID 9296499 DOI: 10.1038/38304  0.336
1997 Jenster G, Spencer TE, Burcin MM, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor induction of gene transcription: A two-step model Proceedings of the National Academy of Sciences of the United States of America. 94: 7879-7884. PMID 9223281 DOI: 10.1073/pnas.94.15.7879  0.329
1997 Mani SK, Blaustein JD, O'Malley BW. Progesterone receptor function from a behavioral perspective. Hormones and Behavior. 31: 244-55. PMID 9213138 DOI: 10.1006/Hbeh.1997.1393  0.407
1997 Shibata H, Nawaz Z, Tsai SY, O'Malley BW, Tsai MJ. Gene silencing by chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI) is mediated by transcriptional corepressors, nuclear receptor-corepressor (N-CoR) and silencing mediator for retinoic acid receptor and thyroid hormone receptor (SMRT) Molecular Endocrinology. 11: 714-724. PMID 9171235 DOI: 10.1210/Mend.11.6.0002  0.455
1997 Bai W, Rowan BG, Allgood VE, O'Malley BW, Weigel NL. Differential phosphorylation of chicken progesterone receptor in hormone-dependent and ligand-independent activation. The Journal of Biological Chemistry. 272: 10457-63. PMID 9099688 DOI: 10.1074/JBC.272.16.10457  0.302
1997 Wang Y, DeMayo FJ, Tsai SY, O'Malley BW. Ligand-inducible and liver-specific target gene expression in transgenic mice. Nature Biotechnology. 15: 239-43. PMID 9062922 DOI: 10.1038/Nbt0397-239  0.33
1997 Allgood VE, Zhang Y, O'Malley BW, Weigel NL. Analysis of chicken progesterone receptor function and phosphorylation using an adenovirus-mediated procedure for high-efficiency DNA transfer Biochemistry. 36: 224-232. PMID 8993337 DOI: 10.1021/Bi961125C  0.396
1996 Mani SK, Allen JM, Lydon JP, Mulac-Jericevic B, Blaustein JD, DeMayo FJ, Conneely O, O'Malley BW. Dopamine requires the unoccupied progesterone receptor to induce sexual behavior in mice. Molecular Endocrinology (Baltimore, Md.). 10: 1728-37. PMID 8961281 DOI: 10.1210/Mend.10.12.8961281  0.337
1996 Xu J, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. The extreme C terminus of progesterone receptor contains a transcriptional repressor domain that functions through a putative corepressor Proceedings of the National Academy of Sciences of the United States of America. 93: 12195-12199. PMID 8901556 DOI: 10.1073/Pnas.93.22.12195  0.425
1996 Mcinerney EM, Tsai MJ, O'Malley BW, Katzenellenbogen BS. Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator Proceedings of the National Academy of Sciences of the United States of America. 93: 10069-10073. PMID 8816752 DOI: 10.1073/Pnas.93.19.10069  0.459
1996 Smith CL, Oñate SA, Tsai MJ, O'Malley BW. CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription. Proceedings of the National Academy of Sciences of the United States of America. 93: 8884-8. PMID 8799122 DOI: 10.1073/Pnas.93.17.8884  0.498
1996 Lydon JP, DeMayo FJ, Conneely OM, O'Malley BW. Reproductive phenotpes of the progesterone receptor null mutant mouse. The Journal of Steroid Biochemistry and Molecular Biology. 56: 67-77. PMID 8603049 DOI: 10.1016/0960-0760(95)00254-5  0.407
1995 Smith CL, Conneely OM, O'Malley BW. Oestrogen receptor activation in the absence of ligand. Biochemical Society Transactions. 23: 935-939. PMID 8654870 DOI: 10.1042/Bst0230935  0.361
1995 Nawaz Z, Tsai MJ, O'Malley BW. Specific mutations in the ligand binding domain selectively abolish the silencing function of human thyroid hormone receptor β Proceedings of the National Academy of Sciences of the United States of America. 92: 11691-11695. PMID 8524830 DOI: 10.1073/Pnas.92.25.11691  0.445
1995 Law SW, Apostolakis EM, Samora PJ, O'Malley BW, Clark JH. Hormonal regulation of hypothalamic gene expression: identification of multiple novel estrogen induced genes. The Journal of Steroid Biochemistry and Molecular Biology. 51: 131-6. PMID 7981121 DOI: 10.1016/0960-0760(94)90085-X  0.343
1995 Blanco JC, Wang IM, Tsai SY, Tsai MJ, O'Malley BW, Jurutka PW, Haussler MR, Ozato K. Transcription factor TFIIB and the vitamin D receptor cooperatively activate ligand-dependent transcription. Proceedings of the National Academy of Sciences of the United States of America. 92: 1535-9. PMID 7878015 DOI: 10.1073/Pnas.92.5.1535  0.313
1995 Baniahmad A, Leng X, Burris TP, Tsai SY, Tsai MJ, O'Malley BW. The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing. Molecular and Cellular Biology. 15: 76-86. PMID 7799971 DOI: 10.1128/Mcb.15.1.76  0.64
1995 Leng X, Blanco J, Tsai SY, Ozato K, O'Malley BW, Tsai MJ. Mouse retinoid X receptor contains a separable ligand-binding and transactivation domain in its E region. Molecular and Cellular Biology. 15: 255-63. PMID 7799932 DOI: 10.1128/Mcb.15.1.255  0.387
1995 Baniahmad C, Nawaz Z, Baniahmad A, Gleeson MAG, Tsai MJ, O'Malley BW. Enhancement of human estrogen receptor activity by SPT6: A potential coactivator Molecular Endocrinology. 9: 34-43. PMID 7760849 DOI: 10.1210/Mend.9.1.7760849  0.445
1995 O'Malley BW, Schrader WT, Mani S, Smith C, Weigel NL, Conneely OM, Clark JH. An alternative ligand-independent pathway for activation of steroid receptors. Recent Progress in Hormone Research. 50: 333-47. PMID 7740165 DOI: 10.1016/B978-0-12-571150-0.50020-2  0.457
1995 Burris TP, Nawaz Z, Tsai MJ, O'Malley BW. A nuclear hormone receptor-associated protein that inhibits transactivation by the thyroid hormone and retinoic acid receptors Proceedings of the National Academy of Sciences of the United States of America. 92: 9525-9529. PMID 7568167 DOI: 10.1073/Pnas.92.21.9525  0.657
1995 Lydon JP, DeMayo FJ, Funk CR, Mani SK, Hughes AR, Montgomery CA, Shyamala G, Conneely OM, O'Malley BW. Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes & Development. 9: 2266-78. PMID 7557380 DOI: 10.1101/GAD.9.18.2266  0.3
1995 Oñate SA, Tsai SY, Tsai MJ, O'Malley BW. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science (New York, N.Y.). 270: 1354-7. PMID 7481822 DOI: 10.1126/science.270.5240.1354  0.365
1994 Beekman JM, Allan GF, Tsai SY, Tsai MJ, O'Malley BW. Transcriptional activation by the estrogen receptor requires a conformational change in the ligand binding domain. Molecular Endocrinology (Baltimore, Md.). 7: 1266-74. PMID 8264659 DOI: 10.1210/Mend.7.10.8264659  0.396
1994 Salomonsson M, Häggblad J, O'Malley BW, Sitbon GM. The human estrogen receptor hormone binding domain dimerizes independently of ligand activation. The Journal of Steroid Biochemistry and Molecular Biology. 48: 447-52. PMID 8180105 DOI: 10.1016/0960-0760(94)90192-9  0.386
1994 Wang Y, O'Malley BW, Tsai SY, O'Malley BW. A regulatory system for use in gene transfer. Proceedings of the National Academy of Sciences of the United States of America. 91: 8180-4. PMID 8058776 DOI: 10.1073/PNAS.91.17.8180  0.34
1994 Zeng Z, Allan GF, Thaller C, Cooney AJ, Tsai SY, O'malley BW, Tsai M. Detection of potential ligands for nuclear receptors in cellular extracts Endocrinology. 135: 248-252. PMID 8013359 DOI: 10.1210/Endo.135.1.8013359  0.385
1994 Mani SK, Blaustein JD, Allen JM, Law SW, O'Malley BW, Clark JH. Inhibition of rat sexual behavior by antisense oligonucleotides to the progesterone receptor. Endocrinology. 135: 1409-14. PMID 7925102 DOI: 10.1210/Endo.135.4.7925102  0.337
1994 Mani SK, Allen JM, Clark JH, Blaustein JD, O'Malley BW. Convergent pathways for steroid hormone- and neurotransmitter-induced rat sexual behavior. Science (New York, N.Y.). 265: 1246-9. PMID 7915049 DOI: 10.1126/Science.7915049  0.401
1994 Kieback DG, Runnebaum IB, Moebus VJ, Kreienberg R, McCamant SK, Edwards CL, Jones LA, Tsai MJ, O'Malley BW. Chicken ovalbumin upstream promoter transcription factor (COUP-TF): an orphan steroid receptor with a specific pattern of differential expression in human ovarian cancer cell lines. Gynecologic Oncology. 51: 167-70. PMID 7903949 DOI: 10.1006/GYNO.1993.1266  0.336
1994 Chen F, Cooney AJ, Wang Y, Law SW, O'Malley BW. Cloning of a novel orphan receptor (GCNF) expressed during germ cell development. Molecular Endocrinology. 8: 1434-1444. PMID 7854358 DOI: 10.1210/Mend.8.10.7854358  0.416
1994 Nawaz Z, Baniahmad C, Burris TP, O'Malley BW, Stillman DJ, TsaiTsaiTsai MJ. The yeast SIN3 gene product negatively regulates the activity of the human progesterone receptor and positively regulates the activities of GAL4 and the HAP1 activator Mgg Molecular &Amp; General Genetics. 245: 724-733. PMID 7830720 DOI: 10.1007/Bf00297279  0.633
1993 Poletti A, Conneely OM, McDonnell DP, Schrader WT, O'Malley BW, Weigel NL. Chicken progesterone receptor expressed in Saccharomyces cerevisiae is correctly phosphorylated at all four Ser-Pro phosphorylation sites. Biochemistry. 32: 9563-9. PMID 8373763 DOI: 10.1021/Bi00088A007  0.556
1993 Ing NH, Beekman JM, Kessler DJ, Murphy M, Jayaraman K, Zendegui JG, Hogan ME, O'Malley BW, Tsai MJ. In vivo transcription of a progesterone-responsive gene is specifically inhibited by a triplex-forming oligonucleotide. Nucleic Acids Research. 21: 2789-96. PMID 8332487 DOI: 10.1093/Nar/21.12.2789  0.417
1993 Smith CL, Conneely OM, O'Malley BW. Modulation of the ligand-independent activation of the human estrogen receptor by hormone and antihormone. Proceedings of the National Academy of Sciences of the United States of America. 90: 6120-4. PMID 8327492 DOI: 10.1073/Pnas.90.13.6120  0.416
1993 Leng X, Tsai SY, O'Malley BW, Tsai MJ. Ligand-dependent conformational changes in thyroid hormone and retinoic acid receptors are potentially enhanced by heterodimerization with retinoic X receptor Journal of Steroid Biochemistry and Molecular Biology. 46: 643-661. PMID 8274399 DOI: 10.1016/0960-0760(93)90306-H  0.408
1993 Vegeto E, Shahbaz MM, Wen DX, Goldman ME, O'Malley BW, McDonnell DP. Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function. Molecular Endocrinology (Baltimore, Md.). 7: 1244-55. PMID 8264658 DOI: 10.1210/Mend.7.10.8264658  0.6
1993 Chen F, Law SW, O'malley BW. Identification of two mPPAR related receptors and evidence for the existence of five subfamily members. Biochemical and Biophysical Research Communications. 196: 671-677. PMID 8240342 DOI: 10.1006/Bbrc.1993.2302  0.383
1993 Fuqua SA, Allred DC, Elledge RM, Krieg SL, Benedix MG, Nawaz Z, O'Malley BW, Greene GL, McGuire WL. The ER-positive/PgR-negative breast cancer phenotype is not associated with mutations within the DNA binding domain. Breast Cancer Research and Treatment. 26: 191-202. PMID 8219256 DOI: 10.1007/Bf00689692  0.367
1993 Allan GF, Tsai SY, Tsai MJ, O'Malley BW. Ligand-dependent conformational changes in the progesterone receptor are necessary for events that follow DNA binding. Proceedings of the National Academy of Sciences of the United States of America. 89: 11750-4. PMID 1465392 DOI: 10.1073/Pnas.89.24.11750  0.387
1992 Power RF, Mani SK, Codina J, Conneely OM, O'Malley BW. Dopaminergic and ligand-independent activation of steroid hormone receptors. Science (New York, N.Y.). 254: 1636-9. PMID 1749936 DOI: 10.1126/SCIENCE.1749936  0.315
1992 O'Malley BW, Tsai SY, Bagchi M, Weigel NL, Schrader WT, Tsai MJ. Molecular mechanism of action of a steroid hormone receptor. Recent Progress in Hormone Research. 47: 1-24; discussion 24-. PMID 1745818 DOI: 10.1016/B978-0-12-571147-0.50005-6  0.484
1992 Weigel NL, Carter TH, Schrader WT, O'Malley BW. Chicken progesterone receptor is phosphorylated by a DNA-dependent protein kinase during in vitro transcription assays. Molecular Endocrinology (Baltimore, Md.). 6: 8-14. PMID 1738374 DOI: 10.1210/Mend.6.1.1738374  0.396
1992 Pham TA, McDonnell DP, Tsai MJ, O'Malley BW. Modulation of progesterone receptor binding to progesterone response elements by positioned nucleosomes. Biochemistry. 31: 1570-8. PMID 1737013 DOI: 10.1021/Bi00120A039  0.599
1992 Vegeto E, Allan GF, Schrader WT, Tsai MJ, McDonnell DP, O'Malley BW. The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor. Cell. 69: 703-13. PMID 1586949 DOI: 10.1016/0092-8674(92)90234-4  0.608
1992 Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Ligand and DNA-dependent phosphorylation of human progesterone receptor in vitro. Proceedings of the National Academy of Sciences of the United States of America. 89: 2664-8. PMID 1557371 DOI: 10.1073/Pnas.89.7.2664  0.464
1992 O'Malley BW, Tsai MJ. Molecular pathways of steroid receptor action. Biology of Reproduction. 46: 163-7. PMID 1536890 DOI: 10.1095/BIOLREPROD46.2.163  0.333
1992 Pham TA, Hwung YP, Santiso-Mere D, McDonnell DP, O'Malley BW. Ligand-dependent and -independent function of the transactivation regions of the human estrogen receptor in yeast. Molecular Endocrinology (Baltimore, Md.). 6: 1043-50. PMID 1508220 DOI: 10.1210/Mend.6.7.1508220  0.634
1992 Law SW, Conneely OM, DeMayo FJ, O'Malley BW. Identification of a new brain-specific transcription factor, NURR1. Molecular Endocrinology. 6: 2129-2135. PMID 1491694 DOI: 10.1210/Mend.6.12.1491694  0.381
1992 McDonnell DP, Vegeto E, O'Malley BW. Identification of a negative regulatory function for steroid receptors Proceedings of the National Academy of Sciences of the United States of America. 89: 10563-10567. PMID 1438251 DOI: 10.1073/Pnas.89.22.10563  0.64
1992 Bagchi MK, Tsai MJ, O'Malley BW, Tsai SY. Analysis of the mechanism of steroid hormone receptor-dependent gene activation in cell-free systems. Endocrine Reviews. 13: 525-35. PMID 1425487 DOI: 10.1210/Edrv-13-3-525  0.372
1992 Power RF, Conneely OM, O'Malley BW. New insights into activation of the steroid hormone receptor superfamily. Trends in Pharmacological Sciences. 13: 318-23. PMID 1413090 DOI: 10.1016/0165-6147(92)90099-R  0.455
1992 Baniahmad A, Tsai SY, O'Malley BW, Tsai MJ. Kindred S thyroid hormone receptor is an active and constitutive silencer and a repressor for thyroid hormone and retinoic acid responses. Proceedings of the National Academy of Sciences of the United States of America. 89: 10633-7. PMID 1359543 DOI: 10.1073/Pnas.89.22.10633  0.457
1992 O'Malley BW, Conneely OM. Orphan receptors: in search of a unifying hypothesis for activation. Molecular Endocrinology (Baltimore, Md.). 6: 1359-61. PMID 1331771 DOI: 10.1210/Mend.6.9.1331771  0.443
1992 Cooney AJ, Tsai SY, O'Malley BW, Tsai MJ. Chicken ovalbumin upstream promoter transcription factor (COUP-TF) dimers bind to different GGTCA response elements, allowing COUP-TF to repress hormonal induction of the vitamin D3, thyroid hormone, and retinoic acid receptors. Molecular and Cellular Biology. 12: 4153-63. PMID 1324415 DOI: 10.1128/Mcb.12.9.4153  0.413
1992 Poletti A, Weigel NL, McDonnell DP, Schrader WT, O'Malley BW, Conneely OM. A novel, highly regulated, rapidly inducible system for the expression of chicken progesterone receptor, cPRA, in Saccharomyces cerevisiae. Gene. 114: 51-8. PMID 1316867 DOI: 10.1016/0378-1119(92)90706-U  0.636
1991 Elliston JF, Fawell SE, Klein-Hitpass L, Tsai SY, Tsai MJ, Parker MG, O'Malley BW. Mechanism of estrogen receptor-dependent transcription in a cell-free system. Molecular and Cellular Biology. 10: 6607-12. PMID 2247075 DOI: 10.1128/Mcb.10.12.6607  0.485
1991 Denner LA, Weigel NL, Maxwell BL, Schrader WT, O'Malley BW. Regulation of progesterone receptor-mediated transcription by phosphorylation. Science (New York, N.Y.). 250: 1740-3. PMID 2176746 DOI: 10.1126/Science.2176746  0.442
1991 Rodriguez R, Weigel NL, O'Malley BW, Schrader WT. Dimerization of the chicken progesterone receptor in vitro can occur in the absence of hormone and DNA. Molecular Endocrinology (Baltimore, Md.). 4: 1782-90. PMID 2082181 DOI: 10.1210/Mend-4-12-1782  0.393
1991 Power RF, Lydon JP, Conneely OM, O'Malley BW. Dopamine activation of an orphan of the steroid receptor superfamily. Science (New York, N.Y.). 252: 1546-8. PMID 2047861 DOI: 10.1126/Science.2047861  0.402
1991 Cooney AJ, Tsai SY, O'Malley BW, Tsai MJ. Chicken ovalbumin upstream promoter transcription factor binds to a negative regulatory region in the human immunodeficiency virus type 1 long terminal repeat. Journal of Virology. 65: 2853-60. PMID 2033658 DOI: 10.1128/Jvi.65.6.2853-2860.1991  0.345
1991 Allan GF, Tsai SY, O'Malley BW, Tsai MJ. Steroid hormone receptors and in vitro transcription. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 13: 73-8. PMID 2029268 DOI: 10.1002/Bies.950130205  0.47
1991 Pham TA, Elliston JF, Nawaz Z, Mcdonnell DP, Tsai MJ, O'Malley BW. Antiestrogen can establish nonproductive receptor complexes and alter chromatin structure at target enhancers Proceedings of the National Academy of Sciences of the United States of America. 88: 3125-3129. PMID 2014231 DOI: 10.1073/Pnas.88.8.3125  0.631
1991 Fuqua SA, Fitzgerald SD, Chamness GC, Tandon AK, McDonnell DP, Nawaz Z, O'Malley BW, McGuire WL. Variant human breast tumor estrogen receptor with constitutive transcriptional activity. Cancer Research. 51: 105-9. PMID 1988075  0.306
1991 Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Progesterone enhances target gene transcription by receptor free of heat shock proteins hsp90, hsp56, and hsp70. Molecular and Cellular Biology. 11: 4998-5004. PMID 1922029 DOI: 10.1128/Mcb.11.10.4998  0.427
1991 Pham TA, Hwung YP, McDonnell DP, O'Malley BW. Transactivation functions facilitate the disruption of chromatin structure by estrogen receptor derivatives in vivo. The Journal of Biological Chemistry. 266: 18179-87. PMID 1917950  0.334
1991 O'Malley BW. 13th San Antonio Breast Cancer Symposium--Plenary Lecture. Steroid hormone receptors as transactivators of gene expression. Breast Cancer Research and Treatment. 18: 67-71. PMID 1912609 DOI: 10.1007/BF01980968  0.353
1991 McDonnell DP, Nawaz Z, Densmore C, Weigel NL, Pham TA, Clark JH, O'Malley BW. High level expression of biologically active estrogen receptor in Saccharomyces cerevisiae Journal of Steroid Biochemistry and Molecular Biology. 39: 291-297. PMID 1911419 DOI: 10.1016/0960-0760(91)90038-7  0.615
1991 McDonnell DP, Nawaz Z, O'Malley BW. In situ distinction between steroid receptor binding and transactivation at a target gene Molecular and Cellular Biology. 11: 4350-4355. PMID 1875926 DOI: 10.1128/Mcb.11.9.4350  0.629
1990 Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Identification of a functional intermediate in receptor activation in progesterone-dependent cell-free transcription. Nature. 345: 547-50. PMID 2348863 DOI: 10.1038/345547A0  0.479
1990 O'Malley B. MINIREVIEW: The Steroid Receptor Superfamily: More Excitement Predicted for the Future Molecular Endocrinology. 4: 363-369. PMID 2188115 DOI: 10.1210/Mend-4-3-363  0.419
1990 Klein-Hitpass L, Tsai SY, Weigel NL, Allan GF, Riley D, Rodriguez R, Schrader WT, Tsai MJ, O'Malley BW. The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex. Cell. 60: 247-57. PMID 2153462 DOI: 10.1016/0092-8674(90)90740-6  0.464
1990 Power RF, Conneely OM, McDonnell DP, Clark JH, Butt TR, Schrader WT, O'Malley BW. High level expression of a truncated chicken progesterone receptor in Escherichia coli. The Journal of Biological Chemistry. 265: 1419-24. PMID 2153132  0.323
1989 Klein-Hitpass L, Tsai SY, Greene GL, Clark JH, Tsai MJ, O'Malley BW. Specific binding of estrogen receptor to the estrogen response element. Molecular and Cellular Biology. 9: 43-9. PMID 2927397 DOI: 10.1128/Mcb.9.1.43  0.311
1989 Bradshaw MS, Tsai MJ, O'Malley BW. A steroid response element can function in the absence of a distal promoter. Molecular Endocrinology (Baltimore, Md.). 2: 1286-93. PMID 2905764 DOI: 10.1210/Mend-2-12-1286  0.392
1989 O'Malley BW. Did eucaryotic steroid receptors evolve from intracrine gene regulators? Endocrinology. 125: 1119-20. PMID 2759020 DOI: 10.1210/Endo-125-3-1119  0.41
1989 Wang LH, Tsai SY, Cook RG, Beattie WG, Tsai MJ, O'Malley BW. COUP transcription factor is a member of the steroid receptor superfamily. Nature. 340: 163-6. PMID 2739739 DOI: 10.1038/340163A0  0.43
1989 Rodriguez R, Carson MA, Weigel NL, O'Malley BW, Schrader WT. Hormone-induced changes in the in vitro DNA-binding activity of the chicken progesterone receptor. Molecular Endocrinology (Baltimore, Md.). 3: 356-62. PMID 2710137 DOI: 10.1210/Mend-3-2-356  0.425
1989 Mak P, McDonnell DP, Weigel NL, Schrader WT, O'Malley BW. Expression of functional chicken oviduct progesterone receptors in yeast (Saccharomyces cerevisiae). The Journal of Biological Chemistry. 264: 21613-8. PMID 2689442  0.377
1989 Tsai SY, Tsai MJ, O'Malley BW. Cooperative binding of steroid hormone receptors contributes to transcriptional synergism at target enhancer elements. Cell. 57: 443-8. PMID 2566384 DOI: 10.1016/0092-8674(89)90919-7  0.424
1989 Ritchie HH, Hughes MR, Thompson ET, Malloy PJ, Hochberg Z, Feldman D, Pike JW, O'Malley BW. An ochre mutation in the vitamin D receptor gene causes hereditary 1,25-dihydroxyvitamin D3-resistant rickets in three families Proceedings of the National Academy of Sciences of the United States of America. 86: 9783-9787. PMID 2557627 DOI: 10.1073/Pnas.86.24.9783  0.348
1989 McDonnell DP, Pike JW, Drutz DJ, Butt TR, O'Malley BW. Reconstitution of the vitamin D-responsive osteocalcin transcription unit in Saccharomyces cerevisiae. Molecular and Cellular Biology. 9: 3517-23. PMID 2552296 DOI: 10.1128/mcb.9.8.3517-3523.1989  0.515
1989 McDonnell DP, Scott RA, Kerner SA, O'Malley BW, Pike JW. Functional domains of the human vitamin D3 receptor regulate osteocalcin gene expression. Molecular Endocrinology (Baltimore, Md.). 3: 635-44. PMID 2542779 DOI: 10.1210/Mend-3-4-635  0.611
1988 Huckaby CS, Conneely OM, Beattie WG, Dobson AD, Tsai MJ, O'Malley BW. Structure of the chromosomal chicken progesterone receptor gene. Proceedings of the National Academy of Sciences of the United States of America. 84: 8380-4. PMID 3479797 DOI: 10.1073/Pnas.84.23.8380  0.4
1988 Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Purification and characterization of chicken ovalbumin gene upstream promoter transcription factor from homologous oviduct cells. Molecular and Cellular Biology. 7: 4151-8. PMID 3437886 DOI: 10.1128/Mcb.7.12.4151  0.345
1988 Conneely OM, Maxwell BL, Toft DO, Schrader WT, O'Malley BW. The A and B forms of the chicken progesterone receptor arise by alternate initiation of translation of a unique mRNA. Biochemical and Biophysical Research Communications. 149: 493-501. PMID 3426587 DOI: 10.1016/0006-291X(87)90395-0  0.398
1988 Peleg S, Schrader WT, O'Malley BW. Sulfhydryl group content of chicken progesterone receptor: effect of oxidation on DNA binding activity Biochemistry. 27: 358-367. PMID 3349038 DOI: 10.1021/Bi00401A054  0.356
1988 Tsai MJ, Tsai SY, Klein-Hitpass L, Bagchi MK, Elliston JF, Carlstedt-Duke J, Gustafsson JK, O'Malley BW. Cooperative interactions of steroid hormone receptors with their cognate response elements. Cold Spring Harbor Symposia On Quantitative Biology. 53: 829-833. PMID 3254786 DOI: 10.1101/Sqb.1988.053.01.094  0.363
1988 Tsai SY, Carlstedt-Duke J, Weigel NL, Dahlman K, Gustafsson JA, Tsai MJ, O'Malley BW. Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation. Cell. 55: 361-9. PMID 3167984 DOI: 10.1016/0092-8674(88)90059-1  0.429
1988 Komm BS, Terpening CM, Benz DJ, Graeme KA, Gallegos A, Korc M, Greene GL, O'Malley BW, Haussler MR. Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells. Science (New York, N.Y.). 241: 81-4. PMID 3164526 DOI: 10.1126/Science.3164526  0.323
1988 McDonnell DP, Pike JW, O'Malley BW. The vitamin D receptor: a primitive steroid receptor related to thyroid hormone receptor. Journal of Steroid Biochemistry. 30: 41-6. PMID 2838696 DOI: 10.1016/0022-4731(88)90074-X  0.595
1988 Baker AR, McDonnell DP, Hughes M, Crisp TM, Mangelsdorf DJ, Haussler MR, Pike JW, Shine J, O'Malley BW. Cloning and expression of full-length cDNA encoding human vitamin D receptor. Proceedings of the National Academy of Sciences of the United States of America. 85: 3294-8. PMID 2835767 DOI: 10.1073/Pnas.85.10.3294  0.524
1988 Conneely OM, Dobson AD, Carson MA, Maxwell BL, Tsai MJ, Schrader WT, O'Malley BW. Structure-function relationships of the chicken progesterone receptor. Biochemical Society Transactions. 16: 683-7. PMID 2466711 DOI: 10.1042/Bst0160683  0.454
1987 Denner LA, Weigel NL, Schrader WT, O'Malley BW. High-yield high-performance liquid chromatographic analysis of steroid hormone receptors on glass columns Analytical Biochemistry. 161: 291-299. PMID 3578794 DOI: 10.1016/0003-2697(87)90453-2  0.341
1987 Gope ML, Keinānen RA, Kristn PA, Conneely OM, Beattie WG, Zarucki-Schulz T, O'Malley BW, Kulomaa MS. Molecular cloning of the chicken avidin cDNA Nucleic Acids Research. 15: 3595-3606. PMID 3575102 DOI: 10.1093/Nar/15.8.3595  0.317
1987 Conneely OM, Dobson ADW, Tsai M, Beattie WG, Toft DO, Huckaby CS, Zarucki T, Schrader WT, O'Malley BW. Sequence and expression of a functional chicken progesterone receptor. Molecular Endocrinology. 1: 517-525. PMID 3153474 DOI: 10.1210/Mend-1-8-517  0.438
1987 Carson MA, Tsai MJ, Conneely OM, Maxwell BL, Clark JH, Dobson AD, Elbrecht A, Toft DO, Schrader WT, O'Malley BW. Structure-function properties of the chicken progesterone receptor A synthesized from complementary deoxyribonucleic acid. Molecular Endocrinology (Baltimore, Md.). 1: 791-801. PMID 3153463 DOI: 10.1210/Mend-1-11-791  0.466
1987 McDonnell DP, Mangelsdorf DJ, Pike JW, Haussler MR, O'Malley BW. Molecular cloning of complementary DNA encoding the avian receptor for vitamin D. Science (New York, N.Y.). 235: 1214-7. PMID 3029866 DOI: 10.1126/Science.3029866  0.581
1987 Maxwell BL, McDonnell DP, Conneely OM, Schulz TZ, Greene GL, O'Malley BW. Structural organization and regulation of the chicken estrogen receptor. Molecular Endocrinology (Baltimore, Md.). 1: 25-35. PMID 2901032 DOI: 10.1210/Mend-1-1-25  0.572
1986 Kleinsek DA, Beattie WG, Tsai M, O'Malley BW. Molecular cloning of a steroid-regulated 108K heat shock protein gene from hen oviduct. Nucleic Acids Research. 14: 10053-10069. PMID 3027654 DOI: 10.1093/Nar/14.24.10053  0.319
1984 Compton JG, Schrader WT, O'Malley BW. Progesterone receptor binding to DNA: studies by sedimentation velocity methods Journal of Steroid Biochemistry. 20: 89-94. PMID 6708535 DOI: 10.1016/0022-4731(84)90193-6  0.35
1984 Zarucki-Schulz T, Kulomaa MS, Headon DR, Weigel NL, Baez M, Edwards DP, McGuire WL, Schrader WT, O'Malley BW. Molecular cloning of a cDNA for the chicken progesterone receptor B antigen. Proceedings of the National Academy of Sciences of the United States of America. 81: 6358-62. PMID 6593705 DOI: 10.1073/Pnas.81.20.6358  0.357
1984 Sanzo M, Stevens B, Tsai MJ, O'Malley BW. Isolation of a protein fraction that binds preferentially to chicken middle repetitive DNA. Biochemistry. 23: 6491-6498. PMID 6543321 DOI: 10.1021/Bi00321A034  0.305
1984 Dicker PD, Tsai SY, Weigel NL, Tsai M, Schrader WT, O'Malley BW. Monoclonal antibody to the hen oviduct progesterone receptor produced following in vitro immunization. Journal of Steroid Biochemistry. 20: 43-50. PMID 6538613 DOI: 10.1016/0022-4731(84)90187-0  0.332
1984 Alevy MC, Tsai MJ, O'Malley BW. DNase I sensitive domain of the gene coding for the glycolytic enzyme glyceraldehyde 3-phosphate dehydrogenase Biochemistry. 23: 2309-2314. PMID 6329271 DOI: 10.1021/Bi00305A034  0.321
1984 Edwards DP, Weigel NL, Schrader WT, O'Malley BW, McGuire WL. Structural analysis of chicken oviduct progesterone receptor using monoclonal antibodies to the subunit B protein. Biochemistry. 23: 4427-35. PMID 6207857 DOI: 10.1021/Bi00314A029  0.35
1984 Simmen FA, Gope ML, Schulz TZ, Wright DA, Carpenter G, O'Malley BW. Isolation of an evolutionarily conserved epidermal growth factor receptor cDNA from human A431 carcinoma cells Biochemical and Biophysical Research Communications. 124: 125-132. PMID 6093780 DOI: 10.1016/0006-291X(84)90926-4  0.379
1983 Ciejek EM, Tsai M, O'Malley BW. Actively transcribed genes are associated with the nuclear matrix Nature. 306: 607-609. PMID 6646237 DOI: 10.1038/306607A0  0.38
1983 Dean DC, Knoll BJ, Riser ME, O'Malley BW. A 5'-flanking sequence essential for progesterone regulation of an ovalbumin fusion gene. Nature. 305: 551-4. PMID 6621702 DOI: 10.1038/305551A0  0.459
1983 Stein JP, Munjaal RP, Lagace L, Lai EC, O'Malley BW, Means AR. Tissue-specific expression of a chicken calmodulin pseudogene lacking intervening sequences. Proceedings of the National Academy of Sciences of the United States of America. 80: 6485-9. PMID 6579534 DOI: 10.1073/Pnas.80.21.6485  0.317
1983 Compton JG, Schrader WT, O'Malley BW. DNA sequence preference of the progesterone receptor. Proceedings of the National Academy of Sciences of the United States of America. 80: 16-20. PMID 6571991 DOI: 10.1073/Pnas.80.1.16  0.374
1982 Compton JG, Schrader WT, O'Malley BW. Selective binding of chicken progesterone receptor A subunit to a DNA fragment containing ovalbumin gene sequences. Biochemical and Biophysical Research Communications. 105: 96-104. PMID 7092862 DOI: 10.1016/S0006-291X(82)80015-6  0.384
1982 Grody WW, Schrader WT, O'Malley BW. Activation, transformation, and subunit structure of steroid hormone receptors Endocrine Reviews. 3: 141-163. PMID 7044769 DOI: 10.1210/Edrv-3-2-141  0.431
1981 Weigel NL, Pousette A, Schrader WT, O'Malley BW. Analysis of chicken progesterone receptor structure using a spontaneous sheep antibody. Biochemistry. 20: 6798-6803. PMID 7317354 DOI: 10.1021/Bi00527A009  0.378
1981 Hughes MR, Compton JG, Schrader WT, O'Malley BW. Interaction of the chick oviduct progesterone receptor with deoxyribonucleic acid. Biochemistry. 20: 2481-2491. PMID 7236615 DOI: 10.1021/Bi00512A019  0.374
1981 Schrader WT, Birnbaumer ME, Hughes MR, Weigel NL, Grody WW, O'Malley BW. Studies on the structure and function of the chicken progesterone receptor Recent Progress in Hormone Research. 37: 583-633. PMID 7025136 DOI: 10.1016/B978-0-12-571137-1.50017-7  0.361
1981 Woo SL, Beattie WG, Catterall JF, Dugaiczyk A, Staden R, Brownlee GG, O'Malley BW. Complete nucleotide sequence of the chicken chromosomal ovalbumin gene and its biological significance. Biochemistry. 20: 6437-46. PMID 6272839 DOI: 10.1021/Bi00525A024  0.331
1981 Weigel NL, Tash JS, Means AR, Schrader WT, O'Malley BW. Phosphorylation of hen progesterone receptor by cAMP dependent protein kinase. Biochemical and Biophysical Research Communications. 102: 513-9. PMID 6272798 DOI: 10.1016/0006-291X(81)91549-7  0.323
1981 Tsai SY, Tsai MJ, O'Malley BW. Specific 5' flanking sequences are required for faithful initiation of in vitro transcription of the ovalbumin gene. Proceedings of the National Academy of Sciences of the United States of America. 78: 879-83. PMID 6262780 DOI: 10.1073/Pnas.78.2.879  0.334
1981 Schrader WT, O'Malley BW. REGULATION OF GENE EXPRESSION IN THE CHICK OVIDUCT Biochemical Society Transactions. 9: 18P-18P. DOI: 10.1042/Bst009018P  0.327
1980 Swaneck GE, Tsai MJ, O'Malley BW. Induction of ovalbumin mRNA by estrogen in the chick oviduct. Journal of Steroid Biochemistry. 12: 185-91. PMID 7421207 DOI: 10.1016/0022-4731(80)90268-X  0.329
1980 Roop DR, Tsai MJ, O'Malley BW. Definition of the 5' and 3' ends of transcripts of the ovalbumin gene. Cell. 19: 63-8. PMID 7357607 DOI: 10.1016/0092-8674(80)90388-8  0.326
1980 Dure LS, Schrader WT, O'Malley BW. Covalent attachment of a progestational steroid to chick oviduct progesterone receptor by photoaffinity labelling Nature. 283: 784-786. PMID 7188788 DOI: 10.1038/283784A0  0.379
1980 Vedeckis WV, Schrader WT, O'Malley BW. Progesterone-binding components of chick oviduct: analysis of receptor structure by limited proteolysis. Biochemistry. 19: 343-9. PMID 6986170 DOI: 10.1021/Bi00543A015  0.348
1980 Vedeckis WV, Freeman MR, Schrader WT, O'Malley BW. Progesterone-binding components of chick oviduct: partial purification and characterization of a calcium-activated protease which hydrolyzes the progesterone receptor. Biochemistry. 19: 335-43. PMID 6986169 DOI: 10.1021/Bi00543A014  0.354
1980 Lai EC, Woo SL, Bordelon-Riser ME, Fraser TH, O'Malley BW. Ovalbumin is synthesized in mouse cells transformed with the natural chicken ovalbumin gene. Proceedings of the National Academy of Sciences of the United States of America. 77: 244-8. PMID 6928616 DOI: 10.1073/Pnas.77.1.244  0.314
1980 Grody WW, Compton JG, Schrader WT, O'Malley BW. Inactivation of chick oviduct progesterone receptors Journal of Steroid Biochemistry. 12: 115-120. PMID 6448321 DOI: 10.1016/0022-4731(80)90260-5  0.392
1980 Colbert DA, Knoll BJ, Woo SL, Mace ML, Tsai MJ, O'Malley BW. Differential hormonal responsiveness of the ovalbumin gene and its pseudogenes in the chick oviduct. Biochemistry. 19: 5586-92. PMID 6257282 DOI: 10.1021/Bi00565A020  0.33
1980 Tsai SY, Roop DR, Stumph WE, Tsai MJ, O'Malley BW. Evidence that deoxyribonucleic acid sequences flanking the ovalbumin gene are not transcribed. Biochemistry. 19: 1755-61. PMID 6246933 DOI: 10.1021/Bi00550A005  0.327
1979 Tsai SY, Tsai M, Lin C, O'Malley BW. Effect of estrogen on ovalbumin gene expression in differentiated nontarget tissues. Biochemistry. 18: 5726-5731. PMID 518866 DOI: 10.1021/Bi00592A032  0.328
1979 Swaneck GE, Kreuzaler F, Tsai MJ, O'Malley BW. Absence of an obligatory lag period in the induction of ovalbumin mRNA by estrogen. Biochemical and Biophysical Research Communications. 88: 1412-8. PMID 475790 DOI: 10.1016/0006-291X(79)91137-9  0.36
1979 Robertson MA, Staden R, Tanaka Y, Catterall JF, O'Malley BW, Brownlee GG. Sequence of three introns in the chick ovalbumin gene. Nature. 278: 370-2. PMID 423993 DOI: 10.1038/278370A0  0.317
1979 Woo SL, Tsai SY, Tsai MJ, Lai EC, Mace ML, O'Malley BW. Cloning and expression of a pseudo-ovalbumin gene. Biochemical and Biophysical Research Communications. 89: 997-1005. PMID 385002 DOI: 10.1016/0006-291X(79)91876-X  0.337
1979 Tsai MJ, Tsai SY, Chang CW, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. In vitro transcription of the ovalbumin gene. Biochimica Et Biophysica Acta. 521: 689-707. PMID 367441 DOI: 10.1016/0005-2787(78)90309-X  0.32
1979 Schwartz RJ, Chang C, Schrader WT, O'Malley BW. Effect of progesterone receptors on transcription. Annals of the New York Academy of Sciences. 286: 147-60. PMID 363019 DOI: 10.1111/J.1749-6632.1977.Tb29413.X  0.434
1979 Dugaiczyk A, Woo SL, Colbert DA, Lai EC, Mace ML, O'Malley BW. The ovalbumin gene: cloning and molecular organization of the entire natural gene. Proceedings of the National Academy of Sciences of the United States of America. 76: 2253-7. PMID 287066 DOI: 10.1073/Pnas.76.5.2253  0.306
1979 Swaneck GE, Nordstrom JL, Kreuzaler F, Tsai MJ, O'Malley BW. Effect of estrogen on gene expression in chicken oviduct: evidence for transcriptional control of ovalbumin gene. Proceedings of the National Academy of Sciences of the United States of America. 76: 1049-53. PMID 286292 DOI: 10.1073/Pnas.76.3.1049  0.372
1979 O'Malley BW, Roop DR, Lai EC, Nordstrom JL, Catterall JF, Swaneck GE, Colbert DA, Tsai MJ, Dugaiczyk A, Woo SL. The ovalbumin gene: organization, structure, transcription, and regulation. Recent Progress in Hormone Research. 35: 1-46. PMID 229523 DOI: 10.1016/B978-0-12-571135-7.50005-9  0.436
1979 Coty WA, Schrader WT, O'Malley BW. Purification and characterization of the chick oviduct progesterone receptor A subunit. Journal of Steroid Biochemistry. 10: 1-12. PMID 229346 DOI: 10.1016/0022-4731(79)90134-1  0.316
1979 Schroeder HW, Liarakos CD, Gupta RC, Randerath K, O'Malley BW. Ribosome binding site analysis of ovalbumin messenger ribonucleic acid. Biochemistry. 18: 5798-5808. PMID 117832 DOI: 10.1021/Bi00593A009  0.304
1978 Tsai SY, Roop DR, Tsai MJ, Stein JP, Means AR, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. Regulation of the ovomucoid gene. Biochemistry. 17: 5773-80. PMID 728435 DOI: 10.1021/Bi00619A026  0.343
1978 Roop DR, Nordstrom JL, Tsai SY, Tsai MJ, O'Malley BW. Transcription of structural and intervening sequences in the ovalbumin gene and identification of potential ovalbumin mRNA precursors. Cell. 15: 671-85. PMID 719758 DOI: 10.1016/0092-8674(78)90035-1  0.316
1978 Schrader WT, O'Malley BW. Progesterone receptors of chick oviduct. Advances in Experimental Medicine and Biology. 96: 109-36. PMID 636924 DOI: 10.1007/978-1-4757-0722-9_4  0.315
1978 Woo SLC, Dugaiczyk A, Tsai MJ, Lai EC, Catterall JF, O'Malley BW. The ovalbumin gene: Cloning of the natural gene Proceedings of the National Academy of Sciences of the United States of America. 75: 3688-3692. PMID 358194 DOI: 10.1073/Pnas.75.8.3688  0.301
1978 Chan L, Means AR, O'Malley BW. Steroid hormone regulation of specific gene expression. Vitamins and Hormones. 36: 259-95. PMID 84439 DOI: 10.1016/S0083-6729(08)60986-3  0.43
1978 Vedeckis WV, Schrader WT, O'Malley BW. CHAPTER 8 – The Chick Oviduct Progesterone Receptor Biochemical Actions of Hormones. 321-372. DOI: 10.1016/B978-0-12-452805-5.50014-4  0.376
1977 O'Malley BW, Means AR. The mechanism of steroid-hormone regulation of transcription of specific eukaryotic genes. Progress in Nucleic Acid Research and Molecular Biology. 19: 403-19. PMID 798241 DOI: 10.1016/S0079-6603(08)60934-4  0.382
1977 O'Malley BW, Towle HC, Schwartz RJ. Regulation of gene expression in eucaryotes Annual Review of Genetics. 11: 239-275. PMID 339816 DOI: 10.1146/Annurev.Ge.11.120177.001323  0.327
1976 Keller RK, Chandra T, Schrader WT, O'Malley BW. Protein kinases of the chick oviduct: a study of the cytoplasmic and nuclear enzymes. Biochemistry. 15: 1958-1967. PMID 1268202 DOI: 10.1021/Bi00654A025  0.327
1976 Woo SL, O'Malley BW. Hormone inducible messenger RNA. Life Sciences. 17: 1039-47. PMID 1105042 DOI: 10.1016/0024-3205(75)90322-7  0.361
1976 O'Malley BW, Schwartz RJ, Schrader WT. A review of regulation of gene expression by steroid hormone receptors. Journal of Steroid Biochemistry. 7: 1151-1159. PMID 1025362 DOI: 10.1016/0022-4731(76)90048-0  0.424
1976 Chan L, Kohler PO, O'Malley BW. Translation of ovalbumin mRNA in Xenopus laevis oocytes. Characterization of the system and effects of estrogen on injected mRNA populations. The Journal of Clinical Investigation. 57: 576-85. PMID 765353 DOI: 10.1172/Jci108313  0.31
1976 Socher SH, Krall JF, Jaffe RC, O'malley BW. Distribution of Binding Sites for the Progesterone Receptor Within Chick Oviduct Chromatin Endocrinology. 99: 891-900. PMID 182471 DOI: 10.1210/Endo-99-3-891  0.402
1976 Buller RE, Schrader WT, O'Malley BW. Steroids and the practical aspects of performing binding studies. Journal of Steroid Biochemistry. 7: 321-326. PMID 180343 DOI: 10.1016/0022-4731(76)90090-X  0.316
1976 Buller RE, Schwartz RJ, O'Malley BW. Steroid hormone receptor fraction stimulation of RNA synthesis: A caution Biochemical and Biophysical Research Communications. 69: 106-113. PMID 177017 DOI: 10.1016/S0006-291X(76)80279-3  0.391
1976 Buller RE, O'Malley BW. The biology and mechanism of steroid hormone receptor interaction with the eukaryotic nucleus. Biochemical Pharmacology. 25: 1-12. PMID 175801 DOI: 10.1016/0006-2952(76)90164-7  0.38
1976 O'Malley BW, Schrader WT. The receptors of steroid hormones. Scientific American. 234: 32-43. PMID 174193 DOI: 10.1038/Scientificamerican0276-32  0.398
1976 Tsai SY, Tsai MJ, Schwartz R, Kalimi M, Clark JH, O'Malley BW. Effects of estrogen on gene expression in chick oviduct: nuclear receptor levels and initiation of transcription. Proceedings of the National Academy of Sciences of the United States of America. 72: 4228-32. PMID 172899 DOI: 10.1073/Pnas.72.11.4228  0.403
1975 Keller RK, Socher SH, Krall JF, Chandra T, O'Malley BW. Fractionation of chick oviduct chromatin: IV. Association of protein kinase with transcriptionally active chromatin. Biochemical and Biophysical Research Communications. 66: 453-459. PMID 1101886 DOI: 10.1016/0006-291X(75)90532-X  0.303
1975 Means AR, Woo S, Harris SE, O'Malley BW. Estrogen induction of ovalbumin mRNA: evidence for transcription control. Molecular and Cellular Biochemistry. 7: 33-42. PMID 1094273 DOI: 10.1007/Bf01732161  0.376
1975 Jaffe RC, Socher SH, O'Malley BW. An analysis of the binding of the chick oviduct progesterone-receptor to chromatin. Biochimica Et Biophysica Acta. 399: 403-419. PMID 169905 DOI: 10.1016/0304-4165(75)90269-X  0.404
1975 Smith RG, Iramain CA, Buttram VC, O'Malley BW. Purification of human uterine progesterone receptor. Nature. 253: 271-2. PMID 163440 DOI: 10.1038/253271A0  0.366
1975 Harris SE, Rosen JM, Means AR, O'Malley BW. Use of a specific probe for ovalbumin messenger RNA to quantitate estrogen-induced gene transcripts. Biochemistry. 14: 2072-81. PMID 50081 DOI: 10.1021/Bi00681A006  0.362
1975 Rosen JM, O'Malley BW. CHAPTER 9 – Hormonal Regulation of Specific Gene Expression in the Chick Oviduct Biochemical Actions of Hormones. 271-315. DOI: 10.1016/B978-0-12-452803-1.50016-1  0.361
1974 O'Malley BW, Means AR. Female steroid hormones and target cell nuclei. Science (New York, N.Y.). 183: 610-20. PMID 4359082 DOI: 10.1126/Science.183.4125.610  0.433
1974 Harris SE, Means AR, Mitchell WM, O'Malley BW. Synthesis of (3H)DNA complementary to ovalbumin messenger RNA: evidence for limited copies of the ovalbumin gene in chick oviduct. Proceedings of the National Academy of Sciences of the United States of America. 70: 3776-80. PMID 4129926 DOI: 10.1073/Pnas.70.12.3776  0.309
1974 Buller RE, Schrader WT, O'Malley BW. 218. Progesterone receptors: Activation and kinetic studies of binding to nuclear acceptor sites Journal of Steroid Biochemistry. 5: 347-348. DOI: 10.1016/0022-4731(74)90363-X  0.371
1974 Harris S, Rosen J, Means A, O'malley B. 190. Mechanism of estrogen action: Use of a gentic probe to quantify the concentration of specific messenger RNA molecules in a target cell Journal of Steroid Biochemistry. 5: 341. DOI: 10.1016/0022-4731(74)90335-5  0.3
1973 Liarakos CD, Rosen JM, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. II. Transcription of chick tritiated unique deoxyribonucleic acid as measured by hybridization in ribonucleic acid excess Biochemistry. 12: 2809-2816. PMID 4719120 DOI: 10.1021/Bi00739A006  0.313
1973 Chan L, Means AR, O'Malley BW. Rates of induction of specific translatable messenger RNAs for ovalbumin and avidin by steroid hormones. Proceedings of the National Academy of Sciences of the United States of America. 70: 1870-4. PMID 4515943 DOI: 10.1073/Pnas.70.6.1870  0.338
1973 Socher SH, O'Malley BW. Estrogen-mediated cell proliferation during chick oviduct development and its modulation by progesterone Developmental Biology. 30: 411-417. DOI: 10.1016/0012-1606(73)90098-5  0.343
1972 O'Malley BW, Sherman MR, Toft DO. Progesterone "receptors" in the cytoplasm and nucleus of chick oviduct target tissue. Proceedings of the National Academy of Sciences of the United States of America. 67: 501-8. PMID 5289005 DOI: 10.1073/Pnas.67.2.501  0.385
1972 Comstock JP, Rosenfeld GC, O'Malley BW, Means AR. Estrogen-induced changes in translation, and specific messenger RNA levels during oviduct differentiation. Proceedings of the National Academy of Sciences of the United States of America. 69: 2377-80. PMID 4506757 DOI: 10.1073/Pnas.69.9.2377  0.351
1971 Steggles AW, Spelsberg TC, Glasser SR, O'Malley BW. Soluble complexes between steroid hormones and target-tissue receptors bind specifically to target-tissue chromatin. Proceedings of the National Academy of Sciences of the United States of America. 68: 1479-82. PMID 5283938 DOI: 10.1073/Pnas.68.7.1479  0.375
1970 O'Malley BW, McGuire WL, Kohler PO, Korenman SG. Studies on the mechanism of steroid hormone regulation of synthesis of specific proteins. Recent Progress in Hormone Research. 25: 105-60. PMID 4902947 DOI: 10.1016/B978-0-12-571125-8.50006-5  0.343
1969 Kohler PO, Grimley PM, O'malley BW. Estrogen-Induced Cytodifferentiation Of The Ovalbumin-Secreting Glands Of The Chick Oviduct Journal of Cell Biology. 40: 8-27. PMID 5782453 DOI: 10.1083/Jcb.40.1.8  0.301
1969 O'Malley BW, Aronow A, Peacock AC, Dingman CW. Estrogen-dependent increase in transfer RNA during differentiation of the chick oviduct. Science (New York, N.Y.). 162: 567-8. PMID 5706938 DOI: 10.1126/Science.162.3853.567  0.305
1968 O'Malley BW, McGuire WL, Middleton PA. Altered gene expression during differentiation: population changes in hybridizable RNA after stimulation of the chick oviduct with oestrogen. Nature. 218: 1249-51. PMID 5656650 DOI: 10.1038/2181249A0  0.311
1968 O'Malley BW, McGuire WL. Studies on the mechanism of action of progesterone in regulation of the synthesis of specific protein. The Journal of Clinical Investigation. 47: 654-64. PMID 5637149 DOI: 10.1172/Jci105761  0.337
1968 O'Malley BW, McGuire WL. Studies on the mechanism of estrogen-mediated tissue differentiation: regulation of nuclear transcription and induction of new RNA species. Proceedings of the National Academy of Sciences of the United States of America. 60: 1527-34. PMID 5244758 DOI: 10.1073/Pnas.60.4.1527  0.341
1968 Kohler PO, Grimley PM, O'Malley BW. Protein synthesis: differential stimulation of cell-specific proteins in epithelial cells of chick oviduct. Science (New York, N.Y.). 160: 86-7. PMID 4868141 DOI: 10.1126/Science.160.3823.86  0.32
1967 O'Malley BW. In vitro hormonal induction of a specific protein (avidin) in chick oviduct. Biochemistry. 6: 2546-2551. PMID 6058123 DOI: 10.1021/Bi00860A036  0.317
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