Year |
Citation |
Score |
2022 |
Takemoto JY, Altenberg GA, Poudyal N, Subedi YP, Chang CT. Amphiphilic aminoglycosides: Modifications that revive old natural product antibiotics. Frontiers in Microbiology. 13: 1000199. PMID 36212866 DOI: 10.3389/fmicb.2022.1000199 |
0.749 |
|
2021 |
Subedi YP, Altenberg GA, Chang CT. Advances in the development of connexin hemichannel inhibitors selective toward Cx43. Future Medicinal Chemistry. PMID 33399487 DOI: 10.4155/fmc-2020-0291 |
0.72 |
|
2020 |
Subedi YP, Kjellgren A, Roberts P, Montgomery H, Thackeray N, Fiori MC, Altenberg GA, Chang CT. Amphiphilic aminoglycosides with increased selectivity for inhibition of connexin 43 (Cx43) hemichannels. European Journal of Medicinal Chemistry. 203: 112602. PMID 32679454 DOI: 10.1016/J.Ejmech.2020.112602 |
0.743 |
|
2020 |
Pandey U, Subedi YP, Alfindee MN, Shepherd T, Chang CT. An Alternative and Facile Synthetic Approach for the Precursors of 3- and 6-Aminosugar Donors and Study of One-pot Glycosyltrasferation Chemistry Letters. 49: 99-102. DOI: 10.1246/Cl.190772 |
0.728 |
|
2020 |
Kjellgren A, Fiori MC, AlFindee MN, Subedi YP, Krishnan S, Chang CT, Altenberg GA. Selective Inhibition of Different Isoforms of Connexin Hemichannels by New Aminoglycosides Biophysical Journal. 118: 587a. DOI: 10.1016/J.Bpj.2019.11.3185 |
0.719 |
|
2019 |
Subedi YP, Pandey U, Alfindee MN, Montgomery H, Roberts P, Wight J, Nichols G, Grilley M, Takemoto JY, Chang CT. Scalable and cost-effective tosylation-mediated synthesis of antifungal and fungal diagnostic 6″-Modified amphiphilic kanamycins. European Journal of Medicinal Chemistry. 182: 111639. PMID 31470306 DOI: 10.1016/J.Ejmech.2019.111639 |
0.727 |
|
2019 |
Subedi YP, Chang CT. Cationic Anthraquinone Analogs as Selective Antimicrobials. Microbiology Insights. 12: 1178636119847809. PMID 31205416 DOI: 10.1177/1178636119847809 |
0.754 |
|
2019 |
Alfindee MN, Subedi YP, Grilley MM, Takemoto JY, Chang CT. Antifungal Activities of 4″,6″-Disubstituted Amphiphilic Kanamycins. Molecules (Basel, Switzerland). 24. PMID 31100822 DOI: 10.3390/Molecules24101882 |
0.748 |
|
2019 |
Subedi YP, Roberts P, Grilley M, Takemoto JY, Chang CT. Development of fungal selective amphiphilic kanamycin: cost effective synthesis and use of fluorescent analogs for mode of action investigation. Acs Infectious Diseases. PMID 30674192 DOI: 10.1021/Acsinfecdis.8B00327 |
0.745 |
|
2019 |
Kjellgren A, Fiori MC, AlFindee MN, Subedi YP, Krishnan S, Chang CT, Altenberg GA. Inhibition of Connexion Hemichannels by New Aminoglycosides without Antibiotic Activity Biophysical Journal. 116: 250a. DOI: 10.1016/J.Bpj.2018.11.1367 |
0.752 |
|
2019 |
Chang CT, Takemoto JY, Zhan J. Natural Bioactive Compounds Israel Journal of Chemistry. 59: 325-326. DOI: 10.1002/Ijch.201900050 |
0.355 |
|
2018 |
Subedi YP, Alfindee MN, Shrestha JP, Chang CT. Tuning the biological activity of cationic anthraquinone analogues specifically toward Staphylococcus aureus. European Journal of Medicinal Chemistry. 157: 683-690. PMID 30130717 DOI: 10.1016/J.Ejmech.2018.08.018 |
0.769 |
|
2018 |
Subedi YP, AlFindee MN, Takemoto JY, Chang CT. Antifungal amphiphilic kanamycins: new life for an old drug. Medchemcomm. 9: 909-919. PMID 30108980 DOI: 10.1039/C8Md00155C |
0.742 |
|
2018 |
Subedi YP, Alfindee MN, Shrestha JP, Becker G, Grilley M, Takemoto JY, Chang CT. Synthesis and biological activity investigation of azole and quinone hybridized phosphonates. Bioorganic & Medicinal Chemistry Letters. PMID 30093296 DOI: 10.1016/J.Bmcl.2018.08.002 |
0.766 |
|
2018 |
AlFindee MN, Subedi YP, Fiori MC, Krishnan S, Kjellgren A, Altenberg GA, Chang CT. Inhibition of Connexin Hemichannels by New Amphiphilic Aminoglycosides without Antibiotic Activity. Acs Medicinal Chemistry Letters. 9: 697-701. PMID 30034603 DOI: 10.1021/Acsmedchemlett.8B00158 |
0.745 |
|
2017 |
AlFindee MN, Zhang Q, Subedi YP, Shrestha JP, Kawasaki Y, Grilley M, Takemoto JY, Chang CT. One-step synthesis of carbohydrate esters as antibacterial and antifungal agents. Bioorganic & Medicinal Chemistry. PMID 29305296 DOI: 10.1016/J.Bmc.2017.12.038 |
0.77 |
|
2016 |
Shrestha JP, Baker C, Kawasaki Y, Subedi YP, Vincent de Paul NN, Takemoto JY, Chang CT. Synthesis and bioactivity investigation of quinone-based dimeric cationic triazolium amphiphiles selective against resistant fungal and bacterial pathogens. European Journal of Medicinal Chemistry. 126: 696-704. PMID 27951483 DOI: 10.1016/J.Ejmech.2016.12.008 |
0.782 |
|
2016 |
Zhang Q, Alfindee MN, Shrestha JP, Nziko VP, Kawasaki Y, Peng X, Takemoto JY, Chang CT. Divergent Synthesis of Three Classes of Antifungal Amphiphilic Kanamycin Derivatives. The Journal of Organic Chemistry. PMID 27715046 DOI: 10.1021/Acs.Joc.6B01189 |
0.513 |
|
2016 |
Sun L, Wang S, Zhang S, Shao L, Zhang Q, Skidmore C, Chang CT, Yu D, Zhan J. Characterization of Three Tailoring Enzymes in Dutomycin Biosynthesis and Generation of a Potent Antibacterial Analogue. Acs Chemical Biology. PMID 27195476 DOI: 10.1021/Acschembio.6B00245 |
0.418 |
|
2015 |
Shrestha SK, Grilley M, Anderson T, Dhiman C, Oblad J, Chang CT, Sorensen KN, Takemoto JY. In vitro antifungal synergy between amphiphilic aminoglycoside K20 and azoles against Candida species and Cryptococcus neoformans. Medical Mycology. PMID 26260746 DOI: 10.1093/Mmy/Myv063 |
0.319 |
|
2015 |
Zhang Q, Chang CT. Divergent and facile Lewis acid-mediated synthesis of N-alkyl 2-aminomethylene-1,3-indanediones and 2-alkylamino-1,4-naphthoquinones Tetrahedron Letters. 56: 893-896. DOI: 10.1016/J.Tetlet.2015.01.014 |
0.379 |
|
2014 |
Nziko VPN, Fosso MY, Chang CT. Quantitative structure–activity relationship analysis of antibacterial cationic anthraquinone analogs using Hansch and Fujita models Medicinal Chemistry Research. 23: 5058-5062. DOI: 10.1007/S00044-014-1069-Y |
0.346 |
|
2011 |
Chan KY, Zhang J, Chang CT. Mode of action investigation for the antibacterial cationic anthraquinone analogs. Bioorganic & Medicinal Chemistry Letters. 21: 6353-6356. PMID 21937226 DOI: 10.1016/J.Bmcl.2011.08.107 |
0.55 |
|
2009 |
Zhang J, Chang CT. One-pot synthesis of 1- and 2-substituted naphtho[2,3-d][1,2,3]triazole-4,9-diones. Journal of Organic Chemistry. 74: 4414-4417. PMID 19415905 DOI: 10.1021/Jo9004926 |
0.409 |
|
2009 |
Zhang J, Chang CT. Divergent synthesis of three classes of aryl N-glycosides by solvent control. Journal of Organic Chemistry. 74: 685-695. PMID 19132944 DOI: 10.1021/Jo8020133 |
0.42 |
|
2007 |
Li J, Chiang F, Chen H, Chang CT. Synthesis and antibacterial activity of pyranmycin derivatives with N-1 and O-6 modifications. Bioorganic & Medicinal Chemistry. 15: 7711-7719. PMID 17870543 DOI: 10.1016/J.Bmc.2007.08.059 |
0.385 |
|
2007 |
Li J, Chiang F, Chen H, Chang CT. Investigation of the regioselectivity for the Staudinger reaction and its application for the synthesis of aminoglycosides with N-1 modification Journal of Organic Chemistry. 72: 4055-4066. PMID 17465564 DOI: 10.1021/Jo062588J |
0.396 |
|
2005 |
Li J, Chen H, Chang H, Wang J, Chang CT. Tuning the Regioselectivity of the Staudinger Reaction for the Facile Synthesis of Kanamycin and Neomycin Class Antibiotics with N-1 Modification Organic Letters. 7: 3061-3064. PMID 15987205 DOI: 10.1021/Ol051045D |
0.504 |
|
2005 |
Rai R, McAlexander I, Chang CT. SYNTHETIC GLYCODIVERSIFICATION. FROM AMINOSUGARS TO AMINOGLYCOSIDE ANTIBIOTICS. A REVIEW Organic Preparations and Procedures International. 37: 337-375. DOI: 10.1080/00304940509354969 |
0.563 |
|
2004 |
Wang J, Li J, Czyryca PG, Chang H, Kao J, Chang CT. Synthesis of an unusual branched-chain sugar, 5-C-methyl-L-idopyranose for SAR studies of pyranmycins: implication for the future design of aminoglycoside antibiotics. Bioorganic & Medicinal Chemistry Letters. 14: 4389-4393. PMID 15357959 DOI: 10.1016/J.Bmcl.2004.06.064 |
0.489 |
|
2003 |
Li J, Wang J, Hui Y, Chang CT. Exploring the optimal site for modifications of pyranmycins with the extended arm approach. Organic Letters. 5: 431-434. PMID 12583736 DOI: 10.1021/Ol027288C |
0.396 |
|
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