Yibin Kang, Ph.D. - Publications

Affiliations: 
2000 Duke University, Durham, NC 
Area:
Molecular Biology, Genetics

198 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Celià-Terrassa T, Kang Y. How important is EMT for cancer metastasis? Plos Biology. 22: e3002487. PMID 38324529 DOI: 10.1371/journal.pbio.3002487  0.329
2023 Nolan E, Kang Y, Malanchi I. Mechanisms of Organ-Specific Metastasis of Breast Cancer. Cold Spring Harbor Perspectives in Medicine. PMID 36987584 DOI: 10.1101/cshperspect.a041326  0.394
2022 Shen M, Kang Y. Cancer fitness genes: emerging therapeutic targets for metastasis. Trends in Cancer. PMID 36184492 DOI: 10.1016/j.trecan.2022.08.007  0.312
2022 Kumar S, Nandi A, Singh S, Regulapati R, Li N, Tobias JW, Siebel CW, Blanco MA, Klein-Szanto AJ, Lengner C, Welm AL, Kang Y, Chakrabarti R. Author Correction: Dll1+ quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway. Nature Communications. 13: 3927. PMID 35798701 DOI: 10.1038/s41467-022-30946-9  0.32
2022 Pérez-Núñez I, Rozalén C, Palomeque JÁ, Sangrador I, Dalmau M, Comerma L, Hernández-Prat A, Casadevall D, Menendez S, Liu DD, Shen M, Berenguer J, Ruiz IR, Peña R, Montañés JC, ... ... Kang Y, et al. LCOR mediates interferon-independent tumor immunogenicity and responsiveness to immune-checkpoint blockade in triple-negative breast cancer. Nature Cancer. PMID 35301507 DOI: 10.1038/s43018-022-00339-4  0.679
2022 Meng J, Jiang YZ, Zhao S, Tao Y, Zhang T, Wang X, Zhang Y, Sun K, Yuan M, Chen J, Wei Y, Lan X, Chen M, David CJ, Chang Z, ... ... Kang Y, et al. Tumor-derived Jagged1 promotes cancer progression through immune evasion. Cell Reports. 38: 110492. PMID 35263601 DOI: 10.1016/j.celrep.2022.110492  0.335
2021 Shen M, Smith HA, Wei Y, Jiang YZ, Zhao S, Wang N, Rowicki M, Tang Y, Hang X, Wu S, Wan L, Shao ZM, Kang Y. Pharmacological disruption of the MTDH-SND1 complex enhances tumor antigen presentation and synergizes with anti-PD-1 therapy in metastatic breast cancer. Nature Cancer. 3: 60-74. PMID 35121988 DOI: 10.1038/s43018-021-00280-y  0.334
2021 Shen M, Wei Y, Kim H, Wan L, Jiang YZ, Hang X, Raba M, Remiszewski S, Rowicki M, Wu CG, Wu S, Zhang L, Lu X, Yuan M, Smith HA, ... ... Kang Y, et al. Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis. Nature Cancer. 3: 43-59. PMID 35121987 DOI: 10.1038/s43018-021-00279-5  0.34
2021 Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, Campbell K, Cano A, Casanova J, Christofori G, Dedhar S, Derynck R, Ford HL, Fuxe J, García de Herreros A, ... ... Kang Y, et al. Author Correction: Guidelines and definitions for research on epithelial-mesenchymal transition. Nature Reviews. Molecular Cell Biology. PMID 34654908 DOI: 10.1038/s41580-021-00428-9  0.399
2021 Kumar S, Nandi A, Singh S, Regulapati R, Li N, Tobias JW, Siebel CW, Blanco MA, Klein-Szanto AJ, Lengner C, Welm AL, Kang Y, Chakrabarti R. Dll1 quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway. Nature Communications. 12: 432. PMID 33462238 DOI: 10.1038/s41467-020-20664-5  0.381
2020 Spadazzi C, Mercatali L, Esposito M, Wei Y, Liverani C, De Vita A, Miserocchi G, Carretta E, Zanoni M, Cocchi C, Bongiovanni A, Recine F, Kang Y, Ibrahim T. Trefoil Factor-1 upregulation in estrogen-receptor positive breast cancer correlates with an increased risk of bone metastasis. Bone. 115775. PMID 33249323 DOI: 10.1016/j.bone.2020.115775  0.377
2020 Fang C, Kang Y. Cellular Plasticity in Bone Metastasis. Bone. 115693. PMID 33069922 DOI: 10.1016/j.bone.2020.115693  0.376
2020 Song K, Cai X, Dong Y, Wu H, Wei Y, Shankavaram U, Cui K, Lee Y, Zhu B, Bhattacharjee S, Wang B, Zhang K, Wen A, Wong S, Yu L, ... ... Kang Y, et al. Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development. The Journal of Clinical Investigation. PMID 32960814 DOI: 10.1172/JCI129374  0.316
2020 Fan H, Wang X, Li W, Shen M, Wei Y, Zheng H, Kang Y. ASB13 inhibits breast cancer metastasis through promoting SNAI2 degradation and relieving its transcriptional repression of YAP. Genes & Development. PMID 32943576 DOI: 10.1101/Gad.339796.120  0.5
2020 Li W, Shen M, Jiang YZ, Zhang R, Zheng H, Wei Y, Shao ZM, Kang Y. Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2. Genes & Development. PMID 32943575 DOI: 10.1101/Gad.339804.120  0.453
2020 Pham K, Huynh D, Le L, Delitto D, Yang L, Huang J, Kang Y, Steinberg MB, Li J, Zhang L, Liu D, Tang MS, Liu C, Wang H. E-cigarette promotes breast carcinoma progression and lung metastasis: Macrophage-tumor cells crosstalk and the role of CCL5 and VCAM-1. Cancer Letters. PMID 32829009 DOI: 10.1016/J.Canlet.2020.08.010  0.388
2020 Hoshino A, Kim HS, Bojmar L, Gyan KE, Cioffi M, Hernandez J, Zambirinis CP, Rodrigues G, Molina H, Heissel S, Mark MT, Steiner L, Benito-Martin A, Lucotti S, Di Giannatale A, ... ... Kang Y, et al. Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers. Cell. PMID 32795414 DOI: 10.1016/J.Cell.2020.07.009  0.347
2020 Ghergurovich JM, Esposito M, Chen Z, Wang JZ, Bhatt V, Lan T, White E, Kang Y, Guo JY, Rabinowitz JD. Glucose-6-phosphate dehydrogenase is not essential for K-Ras-driven tumor growth or metastasis. Cancer Research. PMID 32661137 DOI: 10.1158/0008-5472.Can-19-2486  0.425
2020 Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, Campbell K, Cano A, Casanova J, Christofori G, Dedhar S, Derynck R, Ford HL, Fuxe J, García de Herreros A, ... ... Kang Y, et al. Guidelines and definitions for research on epithelial-mesenchymal transition. Nature Reviews. Molecular Cell Biology. PMID 32300252 DOI: 10.1038/S41580-020-0237-9  0.524
2020 Kang Y. Abstract IA13: Identification, validation, and therapeutic targeting of a driver gene in poor-prognosis breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-Ia13  0.451
2019 Shen M, Kang Y. Role Reversal: A Pro-metastatic Function of E-Cadherin. Developmental Cell. 51: 417-419. PMID 31743661 DOI: 10.1016/J.Devcel.2019.10.028  0.388
2019 Liverani C, De Vita A, Minardi S, Kang Y, Mercatali L, Amadori D, Bongiovanni A, La Manna F, Ibrahim T, Tasciotti E. A biomimetic 3D model of hypoxia-driven cancer progression. Scientific Reports. 9: 12263. PMID 31439905 DOI: 10.1038/S41598-019-48701-4  0.46
2019 Zijlstra A, Von Lersner A, Yu D, Borrello L, Oudin M, Kang Y, Sahai E, Fingleton B, Stein U, Cox TR, Price JT, Kato Y, Welm AL, Aguirre-Ghiso JA. The importance of developing therapies targeting the biological spectrum of metastatic disease. Clinical & Experimental Metastasis. PMID 31102066 DOI: 10.1007/S10585-019-09972-3  0.42
2019 Lu W, Kang Y. Epithelial-Mesenchymal Plasticity in Cancer Progression and Metastasis. Developmental Cell. 49: 361-374. PMID 31063755 DOI: 10.1016/J.Devcel.2019.04.010  0.442
2019 Esposito M, Mondal N, Greco TM, Wei Y, Spadazzi C, Lin SC, Zheng H, Cheung C, Magnani JL, Lin SH, Cristea IM, Sackstein R, Kang Y. Bone vascular niche E-selectin induces mesenchymal-epithelial transition and Wnt activation in cancer cells to promote bone metastasis. Nature Cell Biology. PMID 30988423 DOI: 10.1038/S41556-019-0309-2  0.452
2019 Aiello NM, Kang Y. Context-dependent EMT programs in cancer metastasis. The Journal of Experimental Medicine. PMID 30975895 DOI: 10.1084/Jem.20181827  0.452
2019 Celià-Terrassa T, Bastian C, Liu DD, Ell B, Aiello NM, Wei Y, Zamalloa J, Blanco AM, Hang X, Kunisky D, Li W, Williams ED, Rabitz H, Kang Y. Author Correction: Hysteresis control of epithelial-mesenchymal transition dynamics conveys a distinct program with enhanced metastatic ability. Nature Communications. 10: 527. PMID 30692542 DOI: 10.1038/S41467-019-08509-2  0.6
2019 Zhang H, Brown RL, Wei Y, Zhao P, Liu S, Liu X, Deng Y, Hu X, Zhang J, Gao XD, Kang Y, Mercurio AM, Goel HL, Cheng C. CD44 splice isoform switching determines breast cancer stem cell state. Genes & Development. PMID 30692202 DOI: 10.1101/Gad.319889.118  0.365
2019 Monsivais D, Peng J, Kang Y, Matzuk MM. Activin-like kinase 5 (ALK5) inactivation in the mouse uterus results in metastatic endometrial carcinoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 30655341 DOI: 10.1073/Pnas.1806838116  0.395
2019 Ponnapakkam T, Anbalagan M, Saeg F, Emneser W, Kang Y, Gensure R, Rowan B. OR30-4 Parathyroid Hormone-related Peptide Antagonist and Inverse Agonist Reduce Breast Cancer Metastasis to Bone and Bone Loss Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Or30-4  0.387
2019 Fan H, Wang X, Li W, Shen M, Wei Y, Zheng H, Kang Y. Abstract 162: ASB13 inhibits breast cancer progression and metastasis through SNAI2 degradation and transcriptional regulation of YAP Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-162  0.439
2018 Shen M, Jiang YZ, Wei Y, Ell B, Sheng X, Esposito M, Kang J, Hang X, Zheng H, Rowicki M, Zhang L, Shih WJ, Celià-Terrassa T, Liu Y, Cristea I, ... ... Kang Y, et al. Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling. Cancer Cell. PMID 30612941 DOI: 10.1016/J.Ccell.2018.11.016  0.418
2018 Celià-Terrassa T, Bastian C, Liu D, Ell B, Aiello NM, Wei Y, Zamalloa J, Blanco AM, Hang X, Kunisky D, Li W, Williams ED, Rabitz H, Kang Y. Hysteresis control of epithelial-mesenchymal transition dynamics conveys a distinct program with enhanced metastatic ability. Nature Communications. 9: 5005. PMID 30479345 DOI: 10.1038/S41467-018-07538-7  0.677
2018 Zhuo W, Liu Y, Li S, Guo D, Sun Q, Jin J, Rao X, Li M, Sun M, Jiang M, Xu Y, Teng L, Jin Y, Si J, Liu W, ... Kang Y, et al. Long Non-coding RNA GMAN, Upregulated in Gastric Cancer Tissues, is Associated with Metastasis in Patients and Promotes Translation of Ephrin A1 by Competitively Binding GMAN-AS. Gastroenterology. PMID 30445010 DOI: 10.1053/J.Gastro.2018.10.054  0.319
2018 Shen M, Kang Y. Complex interplay between tumor microenvironment and cancer therapy. Frontiers of Medicine. PMID 30097962 DOI: 10.1007/S11684-018-0663-7  0.396
2018 Celià-Terrassa T, Kang Y. Metastatic niche functions and therapeutic opportunities. Nature Cell Biology. 20: 868-877. PMID 30050120 DOI: 10.1038/S41556-018-0145-9  0.4
2018 Shen M, Kang Y. pSTAT3 Reactive Astrocytes Promote Brain Metastasis. Trends in Molecular Medicine. PMID 30029985 DOI: 10.1016/J.Molmed.2018.07.002  0.372
2018 Chakrabarti R, Celià-Terrassa T, Kumar S, Hang X, Wei Y, Choudhury A, Hwang J, Peng J, Nixon B, Grady JJ, DeCoste C, Gao J, van Es JH, Li MO, Aifantis I, ... ... Kang Y, et al. Notch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche. Science (New York, N.Y.). PMID 29773667 DOI: 10.1126/Science.Aan4153  0.328
2018 Anbalagan M, Ponnapakkam T, Kang Y, Gensure RC, Rowan BG. Abstract 4184: Novel parathyroid hormone antagonist prevents breast cancer bone metastasis and cortical bone destruction Tumor Biology. DOI: 10.1158/1538-7445.Am2018-4184  0.404
2017 Jin L, Chun J, Pan C, Kumar A, Zhang G, Ha Y, Li D, Alesi GN, Kang Y, Zhou L, Yu WM, Magliocca KR, Khuri FR, Qu CK, Metallo C, et al. The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer. Molecular Cell. PMID 29249655 DOI: 10.1016/J.Molcel.2017.11.025  0.394
2017 Zheng H, Bae Y, Kasimir-Bauer S, Tang R, Chen J, Ren G, Yuan M, Esposito M, Li W, Wei Y, Shen M, Zhang L, Tupitsyn N, Pantel K, King C, ... ... Kang Y, et al. Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy. Cancer Cell. 32: 731-747.e6. PMID 29232552 DOI: 10.1016/J.Ccell.2017.11.002  0.434
2017 Sánchez-Cid L, Pons M, Lozano JJ, Rubio N, Guerra-Rebollo M, Soriano A, Paris-Coderch L, Segura MF, Fueyo R, Arguimbau J, Zodda E, Bermudo R, Alonso I, Caparrós X, Cascante M, ... ... Kang Y, et al. MicroRNA-200, associated with metastatic breast cancer, promotes traits of mammary luminal progenitor cells. Oncotarget. 8: 83384-83406. PMID 29137351 DOI: 10.18632/Oncotarget.20698  0.384
2017 Esposito M, Guise T, Kang Y. The Biology of Bone Metastasis. Cold Spring Harbor Perspectives in Medicine. PMID 29101110 DOI: 10.1101/Cshperspect.A031252  0.43
2017 Liu DD, Kang Y. Ets2 anchors the prometastatic function of mutant p53 in osteosarcoma. Genes & Development. 31: 1823-1824. PMID 29051386 DOI: 10.1101/Gad.307439.117  0.666
2017 Alečković M, Wei Y, LeRoy G, Sidoli S, Liu DD, Garcia BA, Kang Y. Identification of Nidogen 1 as a lung metastasis protein through secretome analysis. Genes & Development. PMID 28827399 DOI: 10.1101/Gad.301937.117  0.703
2017 Yang M, Bao W, Zhang X, Kang Y, Haffty B, Zhang L. Short-term and long-term clinical outcomes of uncommon types of invasive breast cancers. Histopathology. PMID 28746732 DOI: 10.1111/His.13328  0.364
2017 Aiello NM, Brabletz T, Kang Y, Nieto MA, Weinberg RA, Stanger BZ. Upholding a role for EMT in pancreatic cancer metastasis. Nature. 547: E7-E8. PMID 28682339 DOI: 10.1038/Nature22963  0.393
2017 Ye X, Brabletz T, Kang Y, Longmore GD, Nieto MA, Stanger BZ, Yang J, Weinberg RA. Upholding a role for EMT in breast cancer metastasis. Nature. 547: E1-E3. PMID 28682326 DOI: 10.1038/Nature22816  0.438
2017 Peng J, Kang Y. The Bony Side of Endothelial Cells in Prostate Cancer. Developmental Cell. 41: 451-452. PMID 28586639 DOI: 10.1016/J.Devcel.2017.05.015  0.372
2017 Celià-Terrassa T, Liu DD, Choudhury A, Hang X, Wei Y, Zamalloa J, Alfaro-Aco R, Chakrabarti R, Jiang YZ, Koh BI, Smith HA, DeCoste C, Li JJ, Shao ZM, Kang Y. Normal and cancerous mammary stem cells evade interferon-induced constraint through the miR-199a-LCOR axis. Nature Cell Biology. PMID 28530657 DOI: 10.1038/Ncb3533  0.661
2017 Zheng H, Li W, Kang Y. Tumor-Stroma Interactions in Bone Metastasis: Molecular Mechanisms and Therapeutic Implications. Cold Spring Harbor Symposia On Quantitative Biology. PMID 28381439 DOI: 10.1101/Sqb.2016.81.030775  0.409
2017 Peinado H, Zhang H, Matei IR, Costa-Silva B, Hoshino A, Rodrigues G, Psaila B, Kaplan RN, Bromberg JF, Kang Y, Bissell MJ, Cox TR, Giaccia AJ, Erler JT, Hiratsuka S, et al. Pre-metastatic niches: organ-specific homes for metastases. Nature Reviews. Cancer. PMID 28303905 DOI: 10.1038/Nrc.2017.6  0.376
2017 Jin L, Chun J, Pan C, Alesi GN, Li D, Magliocca KR, Kang Y, Chen ZG, Shin DM, Khuri FR, Fan J, Kang S. Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis. Oncogene. PMID 28218905 DOI: 10.1038/Onc.2017.6  0.462
2017 Celià-Terrassa T, Kang Y. Mouse genomic screen reveals novel host regulator of metastasis. Genome Biology. 18: 31. PMID 28209174 DOI: 10.1186/S13059-017-1170-X  0.343
2017 Li Z, Kang Y. Lipid Metabolism Fuels Cancer's Spread. Cell Metabolism. 25: 228-230. PMID 28178563 DOI: 10.1016/J.Cmet.2017.01.016  0.359
2017 Zhuo W, Kang Y. Lnc-ing ROR1-HER3 and Hippo signalling in metastasis. Nature Cell Biology. 19: 81-83. PMID 28139652 DOI: 10.1038/Ncb3467  0.429
2016 Peinado H, Alecˇković M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar CM, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, ... ... Kang Y, et al. Corrigendum: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nature Medicine. 22: 1502. PMID 27923027 DOI: 10.1038/Nm1216-1502B  0.331
2016 Lu W, Kang Y. Cell lineage determinants as regulators of breast cancer metastasis. Cancer Metastasis Reviews. PMID 27866304 DOI: 10.1007/S10555-016-9644-Y  0.504
2016 Kang Y. Dissecting Tumor-Stromal Interactions in Breast Cancer Bone Metastasis. Endocrinology and Metabolism (Seoul, Korea). PMID 27184014 DOI: 10.3803/Enm.2016.31.2.206  0.465
2016 Celià-Terrassa T, Kang Y. Distinctive properties of metastasis-initiating cells. Genes & Development. 30: 892-908. PMID 27083997 DOI: 10.1101/Gad.277681.116  0.412
2016 Li W, Kang Y. Probing the Fifty Shades of EMT in Metastasis. Trends in Cancer. 2: 65-67. PMID 27042694 DOI: 10.1016/J.Trecan.2016.01.001  0.348
2016 Alesi GN, Jin L, Li D, Magliocca KR, Kang Y, Chen ZG, Shin DM, Khuri FR, Kang S. RSK2 signals through stathmin to promote microtubule dynamics and tumor metastasis. Oncogene. PMID 27041561 DOI: 10.1038/Onc.2016.79  0.473
2016 Li Z, Kang Y. Emerging therapeutic targets in metastatic progression: a focus on breast cancer. Pharmacology & Therapeutics. PMID 27000769 DOI: 10.1016/J.Pharmthera.2016.03.003  0.449
2016 Hu JY, Yi W, Zhang MY, Xu R, Zeng LS, Long XR, Zhou XM, Zheng XS, Kang Y, Wang HY. MicroRNA-711 is a prognostic factor for poor overall survival and has an oncogenic role in breast cancer. Oncology Letters. 11: 2155-2163. PMID 26998141 DOI: 10.3892/Ol.2016.4217  0.401
2016 Zhao P, Xu Y, Wei Y, Qiu Q, Chew TL, Kang Y, Cheng C. The CD44s splice isoform is a central mediator for invadopodia activity. Journal of Cell Science. PMID 26869223 DOI: 10.1242/Jcs.171959  0.341
2016 Kang Y. Imaging TGFβ Signaling in Mouse Models of Cancer Metastasis. Methods in Molecular Biology (Clifton, N.J.). 1344: 219-32. PMID 26520127 DOI: 10.1007/978-1-4939-2966-5_13  0.48
2016 Ducker GS, Esposito MB, Kang Y, Rabinowitz JD. Abstract A14: Role of mitochondrial folate metabolism in cancer cell growth and proliferation Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-A14  0.321
2016 Chakrabarti R, Sinha S, Kang Y. Abstract B21: DNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signaling Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-B21  0.462
2016 Rowan BG, Ponnapakkam T, Anbalagan M, Kang Y, Gensure RC. Abstract LB-259: Bone targeted parathyroid hormone antagonist for prevention of breast cancer bone metastases Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-259  0.44
2015 Bednarz-Knoll N, Efstathiou A, Gotzhein F, Wikman H, Mueller V, Kang Y, Pantel K. Potential Involvement of Jagged1 in Metastatic Progression of Human Breast Carcinomas. Clinical Chemistry. PMID 26721293 DOI: 10.1373/Clinchem.2015.246686  0.432
2015 Alečković M, Kang Y. Welcoming Treat: Astrocyte-Derived Exosomes Induce PTEN Suppression to Foster Brain Metastasis. Cancer Cell. 28: 554-6. PMID 26555172 DOI: 10.1016/J.Ccell.2015.10.010  0.39
2015 Hoshino A, Costa-Silva B, Shen TL, Rodrigues G, Hashimoto A, Tesic Mark M, Molina H, Kohsaka S, Di Giannatale A, Ceder S, Singh S, Williams C, Soplop N, Uryu K, Pharmer L, ... ... Kang Y, et al. Tumour exosome integrins determine organotropic metastasis. Nature. PMID 26524530 DOI: 10.1038/Nature15756  0.376
2015 Ren G, Esposito M, Kang Y. Bone metastasis and the metastatic niche. Journal of Molecular Medicine (Berlin, Germany). PMID 26275789 DOI: 10.1007/S00109-015-1329-4  0.427
2015 Esposito M, Kang Y. RAI2: Linking Retinoic Acid Signaling with Metastasis Suppression. Cancer Discovery. 5: 466-8. PMID 25941336 DOI: 10.1158/2159-8290.Cd-15-0352  0.47
2015 Ale?kovi? M, Kang Y. Bone marrow stroma-derived miRNAs as regulators, biomarkers and therapeutic targets of bone metastasis. Bonekey Reports. 4: 671. PMID 25908970 DOI: 10.1038/Bonekey.2015.38  0.345
2015 Zheng H, Kang Y. Cradle of evil: osteogenic niche for early bone metastasis. Cancer Cell. 27: 153-5. PMID 25670074 DOI: 10.1016/J.Ccell.2015.01.006  0.475
2015 Chakrabarti R, Kang Y. Transplantable mouse tumor models of breast cancer metastasis. Methods in Molecular Biology (Clifton, N.J.). 1267: 367-80. PMID 25636479 DOI: 10.1007/978-1-4939-2297-0_18  0.466
2015 Ale?kovi? M, Kang Y. Regulation of cancer metastasis by cell-free miRNAs. Biochimica Et Biophysica Acta. 1855: 24-42. PMID 25450578 DOI: 10.1016/J.Bbcan.2014.10.005  0.356
2015 Kang Y. Abstract OI-1: Origin of Metastatic Traits in Breast Cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-Oi-1  0.48
2015 La Manna F, Liverani C, De Vita A, Mercatali L, Spadazzi C, Kang Y, Bongiovanni A, Riva N, Ricci M, Calpona S, Amadori D, Ibrahim T. Tumor-stroma cross-talk in the study of the osteoclastogenic potential of a metastatic breast cancer cell line: a coculture system Annals of Oncology. 26: vi22. DOI: 10.1093/Annonc/Mdv336.61  0.438
2015 Liverani C, Mercatali L, Spadazzi C, De Vita A, La Manna F, Kang Y, Bongiovanni A, Riva N, Ricci M, Calpona S, Zavoiu V, Amadori D, Ibrahim T. Everolimus activity on breast cancer and bone cell cocultures Annals of Oncology. 26: vi19. DOI: 10.1093/Annonc/Mdv336.52  0.447
2014 Cicchini M, Chakrabarti R, Kongara S, Price S, Nahar R, Lozy F, Zhong H, Vazquez A, Kang Y, Karantza V. Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity. Autophagy. 10: 2036-52. PMID 25483966 DOI: 10.4161/Auto.34398  0.473
2014 Guo F, Wan L, Zheng A, Stanevich V, Wei Y, Satyshur KA, Shen M, Lee W, Kang Y, Xing Y. Structural insights into the tumor-promoting function of the MTDH-SND1 complex. Cell Reports. 8: 1704-13. PMID 25242325 DOI: 10.1016/J.Celrep.2014.08.033  0.357
2014 Chakrabarti R, Wei Y, Hwang J, Hang X, Andres Blanco M, Choudhury A, Tiede B, Romano RA, DeCoste C, Mercatali L, Ibrahim T, Amadori D, Kannan N, Eaves CJ, Sinha S, ... Kang Y, et al. ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling. Nature Cell Biology. 16: 1004-15, 1-13. PMID 25241036 DOI: 10.1038/Ncb3040  0.435
2014 Zheng H, Shen M, Zha YL, Li W, Wei Y, Blanco MA, Ren G, Zhou T, Storz P, Wang HY, Kang Y. PKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasis. Cancer Cell. 26: 358-73. PMID 25203322 DOI: 10.1016/J.Ccr.2014.07.022  0.447
2014 Ell B, Kang Y. MicroRNAs as regulators of bone homeostasis and bone metastasis. Bonekey Reports. 3: 549. PMID 25120906 DOI: 10.1038/Bonekey.2014.44  0.323
2014 Wan L, Hu G, Wei Y, Yuan M, Bronson RT, Yang Q, Siddiqui J, Pienta KJ, Kang Y. Genetic ablation of metadherin inhibits autochthonous prostate cancer progression and metastasis. Cancer Research. 74: 5336-47. PMID 25074613 DOI: 10.1158/0008-5472.Can-14-1349  0.364
2014 Wan L, Lu X, Yuan S, Wei Y, Guo F, Shen M, Yuan M, Chakrabarti R, Hua Y, Smith HA, Blanco MA, Chekmareva M, Wu H, Bronson RT, Haffty BG, ... ... Kang Y, et al. MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors. Cancer Cell. 26: 92-105. PMID 24981741 DOI: 10.1016/J.Ccr.2014.04.027  0.475
2014 Ell B, Qiu Q, Wei Y, Mercatali L, Ibrahim T, Amadori D, Kang Y. The microRNA-23b/27b/24 cluster promotes breast cancer lung metastasis by targeting metastasis-suppressive gene prosaposin. The Journal of Biological Chemistry. 289: 21888-95. PMID 24966325 DOI: 10.1074/Jbc.M114.582866  0.414
2014 Li W, Kang Y. A new Lnc in metastasis: long noncoding RNA mediates the prometastatic functions of TGF-β. Cancer Cell. 25: 557-9. PMID 24823634 DOI: 10.1016/J.Ccr.2014.04.014  0.372
2014 Wang Y, Lei R, Zhuang X, Zhang N, Pan H, Li G, Hu J, Pan X, Tao Q, Fu D, Xiao J, Chin YE, Kang Y, Yang Q, Hu G. DLC1-dependent parathyroid hormone-like hormone inhibition suppresses breast cancer bone metastasis. The Journal of Clinical Investigation. 124: 1646-59. PMID 24590291 DOI: 10.1172/Jci71812  0.484
2014 Fan J, Shan C, Kang HB, Elf S, Xie J, Tucker M, Gu TL, Aguiar M, Lonning S, Chen H, Mohammadi M, Britton LM, Garcia BA, Alečković M, Kang Y, et al. Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex. Molecular Cell. 53: 534-48. PMID 24486017 DOI: 10.1016/J.Molcel.2013.12.026  0.364
2014 Esposito M, Kang Y. Targeting tumor-stromal interactions in bone metastasis. Pharmacology & Therapeutics. 141: 222-33. PMID 24140083 DOI: 10.1016/J.Pharmthera.2013.10.006  0.415
2014 Deng Y, Huang Z, Xu Y, Jin J, Zhuo W, Zhang C, Zhang X, Shen M, Yan X, Wang L, Wang X, Kang Y, Si J, Zhou T. MiR-215 modulates gastric cancer cell proliferation by targeting RB1. Cancer Letters. 342: 27-35. PMID 23981575 DOI: 10.1016/J.Canlet.2013.08.033  0.333
2014 Cicchini M, Chakrabarti R, Kongara S, Price S, Nahar R, Lozy F, Zhong H, Vazquez A, Kang Y, Karantza V. Abstract LB-138: Autophagy regulator BECN1 acts as a context-dependent tumor suppressor opposing parity-associated and WNT1-driven mammary tumorigenesis Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-138  0.47
2014 Esposito M, Magnani JL, Kang Y. Abstract 4039: Exploration of a potent E-Selectin antagonist (GMI-1271) as a potential novel therapeutic for treating breast cancer metastasis to the bone and lung Cancer Research. 74: 4039-4039. DOI: 10.1158/1538-7445.Am2014-4039  0.458
2014 Bednarz-Knoll N, Efstathiou A, Gotzhein F, Wilkman H, Mueller V, Kang Y, Pantel K. 328 Jagged1 expression and its relevance in metastatic progression of breast cancers European Journal of Cancer. 50: 106-107. DOI: 10.1016/S0959-8049(14)70454-X  0.424
2013 Ell B, Kang Y. MicroRNAs as regulators of tumor-associated stromal cells. Oncotarget. 4: 2166-7. PMID 24293477 DOI: 10.18632/Oncotarget.1625  0.378
2013 Wan L, Pantel K, Kang Y. Tumor metastasis: moving new biological insights into the clinic. Nature Medicine. 19: 1450-64. PMID 24202397 DOI: 10.1038/Nm.3391  0.43
2013 Ell B, Mercatali L, Ibrahim T, Campbell N, Schwarzenbach H, Pantel K, Amadori D, Kang Y. Tumor-induced osteoclast miRNA changes as regulators and biomarkers of osteolytic bone metastasis. Cancer Cell. 24: 542-56. PMID 24135284 DOI: 10.1016/J.Ccr.2013.09.008  0.354
2013 Smith HA, Kang Y. Acute infection induces a metastatic niche: a double menace for cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 4547-9. PMID 23922303 DOI: 10.1158/1078-0432.Ccr-13-1524  0.351
2013 Wan L, Kang Y. Pleiotropic roles of AEG-1/MTDH/LYRIC in breast cancer. Advances in Cancer Research. 120: 113-34. PMID 23889989 DOI: 10.1016/B978-0-12-401676-7.00004-8  0.483
2013 Ell B, Kang Y. Transcriptional control of cancer metastasis. Trends in Cell Biology. 23: 603-11. PMID 23838335 DOI: 10.1016/J.Tcb.2013.06.001  0.399
2013 Leroy G, Dimaggio PA, Chan EY, Zee BM, Blanco MA, Bryant B, Flaniken IZ, Liu S, Kang Y, Trojer P, Garcia BA. A quantitative atlas of histone modification signatures from human cancer cells. Epigenetics & Chromatin. 6: 20. PMID 23826629 DOI: 10.1186/1756-8935-6-20  0.365
2013 Lee ST, Feng M, Wei Y, Li Z, Qiao Y, Guan P, Jiang X, Wong CH, Huynh K, Wang J, Li J, Karuturi KM, Tan EY, Hoon DS, Kang Y, et al. Protein tyrosine phosphatase UBASH3B is overexpressed in triple-negative breast cancer and promotes invasion and metastasis. Proceedings of the National Academy of Sciences of the United States of America. 110: 11121-6. PMID 23784775 DOI: 10.1073/Pnas.1300873110  0.419
2013 Goode GD, Ballard BR, Manning HC, Freeman ML, Kang Y, Eltom SE. Knockdown of aberrantly upregulated aryl hydrocarbon receptor reduces tumor growth and metastasis of MDA-MB-231 human breast cancer cell line. International Journal of Cancer. Journal International Du Cancer. 133: 2769-80. PMID 23733406 DOI: 10.1002/Ijc.28297  0.468
2013 Kang Y, Pantel K. Tumor cell dissemination: emerging biological insights from animal models and cancer patients. Cancer Cell. 23: 573-81. PMID 23680145 DOI: 10.1016/J.Ccr.2013.04.017  0.375
2013 Hitosugi T, Zhou L, Fan J, Elf S, Zhang L, Xie J, Wang Y, Gu TL, Alečković M, LeRoy G, Kang Y, Kang HB, Seo JH, Shan C, Jin P, et al. Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation. Nature Communications. 4: 1790. PMID 23653202 DOI: 10.1038/Ncomms2759  0.372
2013 Zheng H, Kang Y. Multilayer control of the EMT master regulators. Oncogene. 33: 1755-63. PMID 23604123 DOI: 10.1038/Onc.2013.128  0.481
2013 Smith HA, Kang Y. The metastasis-promoting roles of tumor-associated immune cells. Journal of Molecular Medicine (Berlin, Germany). 91: 411-29. PMID 23515621 DOI: 10.1007/S00109-013-1021-5  0.393
2013 Lee JY, Park MK, Park JH, Lee HJ, Shin DH, Kang Y, Lee CH, Kong G. Loss of the polycomb protein Mel-18 enhances the epithelial-mesenchymal transition by ZEB1 and ZEB2 expression through the downregulation of miR-205 in breast cancer. Oncogene. 33: 1325-35. PMID 23474752 DOI: 10.1038/Onc.2013.53  0.379
2013 Ren G, Kang Y. A one-two punch of miR-126/126* against metastasis. Nature Cell Biology. 15: 231-3. PMID 23449143 DOI: 10.1038/Ncb2703  0.32
2013 DeGraff DJ, Robinson VL, Shah JB, Brandt WD, Sonpavde G, Kang Y, Liebert M, Wu XR, Taylor JA. Current preclinical models for the advancement of translational bladder cancer research. Molecular Cancer Therapeutics. 12: 121-30. PMID 23269072 DOI: 10.1158/1535-7163.Mct-12-0508  0.38
2013 Mercatali L, Kang Y, Zanoni M, Liverani C, Carretta E, Ricci M, Riva N, Calpona S, Bongiovanni A, Zoli W, Amadori D, Ibrahim T. Trefoil factor 1 as a predictive factor of bone metastases in breast cancer. Journal of Clinical Oncology. 31: 11022-11022. DOI: 10.1200/Jco.2013.31.15_Suppl.11022  0.409
2013 Kang Y. Abstract IA02: Tumor plasticity and reactive stroma in breast cancer metastasis Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-Ia02  0.542
2013 Cicchini M, Chakarbarti R, Kongara S, Nahar R, Lozy F, Vasquez A, Kang Y, Karantza V. Abstract A004: Expansion of immature mammary epithelial populations promotesWnt1-driven mammary tumorigenesis in an autophagy-deficient mouse model Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-A004  0.439
2013 Kang Y. Abstract IA6: Epithelial-mesenchymal plasticity in breast cancer metastasis Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-Ia6  0.502
2013 Kang Y. Abstract IA27: Cell fate determinants as regulators of cancer metastasis Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-Ia27  0.481
2013 Lyden D, Peinado-Selgas H, Nitadori A, Shen T, Aleckovic M, Kang Y, Bromberg J. Abstract BS03-1: Tumor-derived exosomes promote pre-metastatic niche formation and organotropism Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-Bs03-1  0.449
2012 Sethi N, Kang Y. Notch signaling: mediator and therapeutic target of bone metastasis. Bonekey Reports. 1: 3. PMID 23951415 DOI: 10.1038/Bonekey.2012.2  0.388
2012 Fang W, Wei Y, Kang Y, Landweber LF. Detection of a common chimeric transcript between human chromosomes 7 and 16. Biology Direct. 7: 49. PMID 23273016 DOI: 10.1186/1745-6150-7-49  0.312
2012 Hitosugi T, Zhou L, Elf S, Fan J, Kang HB, Seo JH, Shan C, Dai Q, Zhang L, Xie J, Gu TL, Jin P, Alečković M, LeRoy G, Kang Y, et al. Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth. Cancer Cell. 22: 585-600. PMID 23153533 DOI: 10.1016/J.Ccr.2012.09.020  0.408
2012 Ell B, Kang Y. SnapShot: Bone Metastasis. Cell. 151: 690-690.e1. PMID 23101634 DOI: 10.1016/J.Cell.2012.10.005  0.323
2012 Chakrabarti R, Hwang J, Andres Blanco M, Wei Y, Lukačišin M, Romano RA, Smalley K, Liu S, Yang Q, Ibrahim T, Mercatali L, Amadori D, Haffty BG, Sinha S, Kang Y. Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2. Nature Cell Biology. 14: 1212-22. PMID 23086238 DOI: 10.1038/Ncb2607  0.493
2012 Liang Y, Wu H, Lei R, Chong RA, Wei Y, Lu X, Tagkopoulos I, Kung SY, Yang Q, Hu G, Kang Y. Transcriptional network analysis identifies BACH1 as a master regulator of breast cancer bone metastasis. The Journal of Biological Chemistry. 287: 33533-44. PMID 22875853 DOI: 10.1074/Jbc.M112.392332  0.481
2012 Wendt MK, Schiemann BJ, Parvani JG, Lee YH, Kang Y, Schiemann WP. TGF-β stimulates Pyk2 expression as part of an epithelial-mesenchymal transition program required for metastatic outgrowth of breast cancer. Oncogene. 32: 2005-15. PMID 22710711 DOI: 10.1038/Onc.2012.230  0.472
2012 Blanco MA, LeRoy G, Khan Z, Alečković M, Zee BM, Garcia BA, Kang Y. Global secretome analysis identifies novel mediators of bone metastasis. Cell Research. 22: 1339-55. PMID 22688892 DOI: 10.1038/Cr.2012.89  0.401
2012 Peinado H, Ale?kovi? M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, ... ... Kang Y, et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nature Medicine. 18: 883-91. PMID 22635005 DOI: 10.1038/Nm.2753  0.396
2012 Chakrabarti R, Wei Y, Romano RA, DeCoste C, Kang Y, Sinha S. Elf5 regulates mammary gland stem/progenitor cell fate by influencing notch signaling. Stem Cells (Dayton, Ohio). 30: 1496-508. PMID 22523003 DOI: 10.1002/Stem.1112  0.354
2012 Celià-Terrassa T, Meca-Cortés O, Mateo F, de Paz AM, Rubio N, Arnal-Estapé A, Ell BJ, Bermudo R, Díaz A, Guerra-Rebollo M, Lozano JJ, Estarás C, Ulloa C, Álvarez-Simón D, Milà J, ... ... Kang Y, et al. Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells. The Journal of Clinical Investigation. 122: 1849-68. PMID 22505459 DOI: 10.1172/Jci59218  0.444
2012 Koh BI, Kang Y. The pro-metastatic role of bone marrow-derived cells: a focus on MSCs and regulatory T cells. Embo Reports. 13: 412-22. PMID 22473297 DOI: 10.1038/Embor.2012.41  0.418
2012 Kang Y. Abstract BS1-2: Reactive Stroma as Therapeutic Targets in Breast Cancer Bone Metastasis Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-Bs1-2  0.49
2011 Lu X, Mu E, Wei Y, Riethdorf S, Yang Q, Yuan M, Yan J, Hua Y, Tiede BJ, Lu X, Haffty BG, Pantel K, Massagué J, Kang Y. VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging α4β1-positive osteoclast progenitors. Cancer Cell. 20: 701-14. PMID 22137794 DOI: 10.1016/J.Ccr.2011.11.002  0.618
2011 Sethi N, Kang Y. Notch signalling in cancer progression and bone metastasis. British Journal of Cancer. 105: 1805-10. PMID 22075946 DOI: 10.1038/bjc.2011.497  0.311
2011 Sethi N, Kang Y. Unravelling the complexity of metastasis - molecular understanding and targeted therapies. Nature Reviews. Cancer. 11: 735-48. PMID 21941285 DOI: 10.1038/Nrc3125  0.344
2011 Korpal M, Ell BJ, Buffa FM, Ibrahim T, Blanco MA, Celià-Terrassa T, Mercatali L, Khan Z, Goodarzi H, Hua Y, Wei Y, Hu G, Garcia BA, Ragoussis J, Amadori D, ... ... Kang Y, et al. Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nature Medicine. 17: 1101-8. PMID 21822286 DOI: 10.1038/Nm.2401  0.376
2011 Ibrahim T, Sacanna E, Gaudio M, Mercatali L, Scarpi E, Zoli W, Serra P, Ricci R, Serra L, Kang Y, Amadori D. Role of RANK, RANKL, OPG, and CXCR4 tissue markers in predicting bone metastases in breast cancer patients. Clinical Breast Cancer. 11: 369-75. PMID 21764390 DOI: 10.1016/J.Clbc.2011.05.001  0.405
2011 Zhang X, Tamasi J, Lu X, Zhu J, Chen H, Tian X, Lee TC, Threadgill DW, Kream BE, Kang Y, Partridge NC, Qin L. Epidermal growth factor receptor plays an anabolic role in bone metabolism in vivo. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1022-34. PMID 21542005 DOI: 10.1002/Jbmr.295  0.316
2011 Lu X, Kang Y. Cell fusion hypothesis of the cancer stem cell. Advances in Experimental Medicine and Biology. 714: 129-40. PMID 21506011 DOI: 10.1007/978-94-007-0782-5_6  0.425
2011 Mercatali L, Ibrahim T, Sacanna E, Flamini E, Scarpi E, Calistri D, Ricci M, Serra P, Ricci R, Zoli W, Kang Y, Amadori D. Bone metastases detection by circulating biomarkers: OPG and RANK-L. International Journal of Oncology. 39: 255-61. PMID 21491082 DOI: 10.3892/Ijo.2011.1001  0.319
2011 Blanco MA, Alečković M, Hua Y, Li T, Wei Y, Xu Z, Cristea IM, Kang Y. Identification of staphylococcal nuclease domain-containing 1 (SND1) as a Metadherin-interacting protein with metastasis-promoting functions. The Journal of Biological Chemistry. 286: 19982-92. PMID 21478147 DOI: 10.1074/Jbc.M111.240077  0.467
2011 Blanco MA, Kang Y. Signaling pathways in breast cancer metastasis - novel insights from functional genomics. Breast Cancer Research : Bcr. 13: 206. PMID 21457525 DOI: 10.1186/Bcr2831  0.436
2011 Matsushima K, Isomoto H, Yamaguchi N, Inoue N, Machida H, Nakayama T, Hayashi T, Kunizaki M, Hidaka S, Nagayasu T, Nakashima M, Ujifuku K, Mitsutake N, Ohtsuru A, Yamashita S, ... ... Kang Y, et al. MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells. Journal of Translational Medicine. 9: 30. PMID 21426561 DOI: 10.1186/1479-5876-9-30  0.31
2011 Sethi N, Dai X, Winter CG, Kang Y. Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells. Cancer Cell. 19: 192-205. PMID 21295524 DOI: 10.1016/J.Ccr.2010.12.022  0.451
2011 Tiede B, Kang Y. From milk to malignancy: the role of mammary stem cells in development, pregnancy and breast cancer. Cell Research. 21: 245-57. PMID 21243011 DOI: 10.1038/Cr.2011.11  0.441
2011 Sethi N, Kang Y. Dysregulation of developmental pathways in bone metastasis. Bone. 48: 16-22. PMID 20630490 DOI: 10.1016/J.Bone.2010.07.005  0.436
2010 Lu X, Kang Y. Hypoxia and hypoxia-inducible factors: master regulators of metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 5928-35. PMID 20962028 DOI: 10.1158/1078-0432.Ccr-10-1360  0.378
2010 Sethi N, Yan Y, Quek D, Schupbach T, Kang Y. Rabconnectin-3 is a functional regulator of mammalian Notch signaling. The Journal of Biological Chemistry. 285: 34757-64. PMID 20810660 DOI: 10.1074/Jbc.M110.158634  0.311
2010 Lu X, Lu X, Kang Y. Organ-specific enhancement of metastasis by spontaneous ploidy duplication and cell size enlargement. Cell Research. 20: 1012-22. PMID 20603645 DOI: 10.1038/Cr.2010.93  0.483
2010 Ganapathy V, Ge R, Grazioli A, Xie W, Banach-Petrosky W, Kang Y, Lonning S, McPherson J, Yingling JM, Biswas S, Mundy GR, Reiss M. Targeting the Transforming Growth Factor-beta pathway inhibits human basal-like breast cancer metastasis. Molecular Cancer. 9: 122. PMID 20504320 DOI: 10.1186/1476-4598-9-122  0.358
2010 Lu X, Yan CH, Yuan M, Wei Y, Hu G, Kang Y. In vivo dynamics and distinct functions of hypoxia in primary tumor growth and organotropic metastasis of breast cancer. Cancer Research. 70: 3905-14. PMID 20442288 DOI: 10.1158/0008-5472.Can-09-3739  0.46
2010 Korpal M, Kang Y. Targeting the transforming growth factor-beta signalling pathway in metastatic cancer. European Journal of Cancer (Oxford, England : 1990). 46: 1232-40. PMID 20307969 DOI: 10.1016/J.Ejca.2010.02.040  0.322
2010 Lu X, Bennet B, Mu E, Rabinowitz J, Kang Y. Metabolomic changes accompanying transformation and acquisition of metastatic potential in a syngeneic mouse mammary tumor model Journal of Biological Chemistry. 285: 9317-9321. PMID 20139083 DOI: 10.1074/Jbc.C110.104448  0.438
2010 Lu X, Yang Q, Yuan M, Mu E, Reiss M, Haffty B, Massagué J, Kang Y. Abstract 5763: VCAM1 mediates aggressive bone metastasis outbreak from tumor dormancy by engaging α4β1-positive osteoclast progenitor cells Cancer Research. 70: 5763-5763. DOI: 10.1158/1538-7445.Am10-5763  0.632
2010 Blanco MA, LeRoy G, Zee B, Aleckovic M, Garcia B, Kang Y. Abstract B7: The bone metastasis secretome: Identification of potential therapeutic targets via high-throughput proteomics Clinical Cancer Research. 16. DOI: 10.1158/1078-0432.Tcme10-B7  0.414
2009 Steeg PS, Anderson RL, Bar-Eli M, Chambers AF, Eccles SA, Hunter K, Itoh K, Kang Y, Matrisian LM, Sleeman JP, Theodorescu D, Thompson EW, Welch DR. An open letter to the FDA and other regulatory agencies: Preclinical drug development must consider the impact on metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 4529. PMID 25278743 DOI: 10.1158/1078-0432.Ccr-09-1363  0.319
2009 Lu X, Kang Y. Epidermal growth factor signalling and bone metastasis. British Journal of Cancer. 102: 457-61. PMID 20010942 DOI: 10.1038/sj.bjc.6605490  0.316
2009 Tiede BJ, Owens LA, Li F, DeCoste C, Kang Y. A novel mouse model for non-invasive single marker tracking of mammary stem cells in vivo reveals stem cell dynamics throughout pregnancy. Plos One. 4: e8035. PMID 19946375 DOI: 10.1371/Journal.Pone.0008035  0.338
2009 Lu X, Kang Y. Metalloproteinases and osteoblast EGFR signaling in osteolytic bone metastasis of breast cancer. Cell Cycle (Georgetown, Tex.). 8: 3804-5. PMID 19934661 DOI: 10.4161/Cc.8.23.10104  0.44
2009 Lu X, Kang Y. Cell fusion as a hidden force in tumor progression. Cancer Research. 69: 8536-9. PMID 19887616 DOI: 10.1158/0008-5472.Can-09-2159  0.433
2009 Hu G, Wei Y, Kang Y. The multifaceted role of MTDH/AEG-1 in cancer progression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5615-20. PMID 19723648 DOI: 10.1158/1078-0432.Ccr-09-0049  0.461
2009 Lu X, Kang Y. Chemokine (C-C motif) ligand 2 engages CCR2+ stromal cells of monocytic origin to promote breast cancer metastasis to lung and bone. The Journal of Biological Chemistry. 284: 29087-96. PMID 19720836 DOI: 10.1074/Jbc.M109.035899  0.492
2009 Hu G, Kang Y, Wang XF. From breast to the brain: unraveling the puzzle of metastasis organotropism. Journal of Molecular Cell Biology. 1: 3-5. PMID 19633017 DOI: 10.1093/Jmcb/Mjp005  0.468
2009 Lu X, Wang Q, Hu G, Van Poznak C, Fleisher M, Reiss M, Massagué J, Kang Y. ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis. Genes & Development. 23: 1882-94. PMID 19608765 DOI: 10.1101/Gad.1824809  0.597
2009 Korpal M, Yan J, Lu X, Xu S, Lerit DA, Kang Y. Imaging transforming growth factor-beta signaling dynamics and therapeutic response in breast cancer bone metastasis. Nature Medicine. 15: 960-6. PMID 19597504 DOI: 10.1038/Nm.1943  0.337
2009 Kang Y. Analysis of cancer stem cell metastasis in xenograft animal models. Methods in Molecular Biology (Clifton, N.J.). 568: 7-19. PMID 19582418 DOI: 10.1007/978-1-59745-280-9_2  0.482
2009 Wei Y, Hu G, Kang Y. Metadherin as a link between metastasis and chemoresistance. Cell Cycle (Georgetown, Tex.). 8: 2132-3. PMID 19556872 DOI: 10.4161/Cc.8.14.9070  0.375
2009 Lu X, Kang Y. Efficient acquisition of dual metastasis organotropism to bone and lung through stable spontaneous fusion between MDA-MB-231 variants. Proceedings of the National Academy of Sciences of the United States of America. 106: 9385-90. PMID 19458257 DOI: 10.1073/Pnas.0900108106  0.463
2009 Hu G, Chong RA, Yang Q, Wei Y, Blanco MA, Li F, Reiss M, Au JL, Haffty BG, Kang Y. MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer. Cancer Cell. 15: 9-20. PMID 19111877 DOI: 10.1016/J.Ccr.2008.11.013  0.431
2008 Korpal M, Kang Y. The emerging role of miR-200 family of microRNAs in epithelial-mesenchymal transition and cancer metastasis. Rna Biology. 5: 115-9. PMID 19182522 DOI: 10.4161/Rna.5.3.6558  0.322
2008 Korpal M, Lee ES, Hu G, Kang Y. The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. The Journal of Biological Chemistry. 283: 14910-4. PMID 18411277 DOI: 10.1074/Jbc.C800074200  0.354
2007 Zhu J, Jia X, Xiao G, Kang Y, Partridge NC, Qin L. EGF-like ligands stimulate osteoclastogenesis by regulating expression of osteoclast regulatory factors by osteoblasts: implications for osteolytic bone metastases. The Journal of Biological Chemistry. 282: 26656-64. PMID 17636266 DOI: 10.1074/Jbc.M705064200  0.41
2007 Lu X, Kang Y. Organotropism of breast cancer metastasis. Journal of Mammary Gland Biology and Neoplasia. 12: 153-62. PMID 17566854 DOI: 10.1007/S10911-007-9047-3  0.461
2007 Li F, Tiede B, Massagué J, Kang Y. Beyond tumorigenesis: cancer stem cells in metastasis. Cell Research. 17: 3-14. PMID 17179981 DOI: 10.1038/Sj.Cr.7310118  0.626
2006 Kang Y. New tricks against an old foe: molecular dissection of metastasis tissue tropism in breast cancer. Breast Disease. 26: 129-38. PMID 17473371 DOI: 10.3233/Bd-2007-26111  0.468
2006 Kang Y. Pro-metastasis function of TGFbeta mediated by the Smad pathway. Journal of Cellular Biochemistry. 98: 1380-90. PMID 16598746 DOI: 10.1002/jcb.20928  0.352
2006 Kang Y, He W, Tulley S, Gupta GP, Serganova I, Chen CR, Manova-Todorova K, Blasberg R, Gerald WL, Massagué J. Erratum: Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway (Proceedings of the National Academy of Sciences of the United States of America) (September 27, 2005) 102 (13909-13914) DOI: 10.1073/pnas.0506517102)) Proceedings of the National Academy of Sciences of the United States of America. 103. DOI: 10.1073/Pnas.0603221103  0.608
2005 Gupta GP, Minn AJ, Kang Y, Siegel PM, Serganova I, Cordón-Cardo C, Olshen AB, Gerald WL, Massagué J. Identifying site-specific metastasis genes and functions. Cold Spring Harbor Symposia On Quantitative Biology. 70: 149-58. PMID 16869748 DOI: 10.1101/Sqb.2005.70.018  0.672
2005 Kang Y, He W, Tulley S, Gupta GP, Serganova I, Chen CR, Manova-Todorova K, Blasberg R, Gerald WL, Massagué J. Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway. Proceedings of the National Academy of Sciences of the United States of America. 102: 13909-14. PMID 16172383 DOI: 10.1073/Pnas.0506517102  0.751
2005 Kang Y. Functional genomic analysis of cancer metastasis: biologic insights and clinical implications. Expert Review of Molecular Diagnostics. 5: 385-95. PMID 15934815 DOI: 10.1586/14737159.5.3.385  0.388
2005 Minn AJ, Kang Y, Serganova I, Gupta GP, Giri DD, Doubrovin M, Ponomarev V, Gerald WL, Blasberg R, Massagué J. Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors. The Journal of Clinical Investigation. 115: 44-55. PMID 15630443 DOI: 10.1172/Jci22320  0.745
2004 Kang Y. Breast cancer bone metastasis: Molecular basis of tissue tropism Journal of Musculoskeletal Neuronal Interactions. 4: 379-380. PMID 15758269  0.321
2004 Kang Y, Massagué J. Epithelial-mesenchymal transitions: twist in development and metastasis. Cell. 118: 277-9. PMID 15294153 DOI: 10.1016/J.Cell.2004.07.011  0.605
2003 Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, Cordón-Cardo C, Guise TA, Massagué J. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell. 3: 537-49. PMID 12842083 DOI: 10.1016/S1535-6108(03)00132-6  0.485
2003 Kang Y, Chen CR, Massagué J. A self-enabling TGFbeta response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells. Molecular Cell. 11: 915-26. PMID 12718878 DOI: 10.1016/S1097-2765(03)00109-6  0.508
2002 Xu L, Kang Y, Cöl S, Massagué J. Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus. Molecular Cell. 10: 271-82. PMID 12191473 DOI: 10.1016/S1097-2765(02)00586-5  0.495
2002 Chen CR, Kang Y, Siegel PM, Massagué J. E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression. Cell. 110: 19-32. PMID 12150994 DOI: 10.1016/S0092-8674(02)00801-2  0.318
2002 Ho DN, Coburn GA, Kang Y, Cullen BR, Georgiadis MM. The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor. Proceedings of the National Academy of Sciences of the United States of America. 99: 1888-93. PMID 11854490 DOI: 10.1073/Pnas.042698599  0.472
2002 Wiegand HL, Coburn GA, Zeng Y, Kang Y, Bogerd HP, Cullen BR. Formation of Tap/NXT1 heterodimers activates Tap-dependent nuclear mRNA export by enhancing recruitment to nuclear pore complexes. Molecular and Cellular Biology. 22: 245-56. PMID 11739738 DOI: 10.1128/Mcb.22.1.245-256.2002  0.507
2001 Coburn GA, Wiegand HL, Kang Y, Ho DN, Georgiadis MM, Cullen BR. Using viral species specificity to define a critical protein/RNA interaction surface. Genes & Development. 15: 1194-205. PMID 11358864 DOI: 10.1101/Gad.888201  0.505
2001 Chen CR, Kang Y, Massagué J. Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor β growth arrest program Proceedings of the National Academy of Sciences of the United States of America. 98: 992-999. PMID 11158583 DOI: 10.1073/Pnas.98.3.992  0.566
2000 Neufeld KL, Nix DA, Bogerd H, Kang Y, Beckerle MC, Cullen BR, White RL. Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm. Proceedings of the National Academy of Sciences of the United States of America. 97: 12085-90. PMID 11035805 DOI: 10.1073/Pnas.220401797  0.503
2000 Kang Y, Bogerd HP, Cullen BR. Analysis of cellular factors that mediate nuclear export of RNAs bearing the Mason-Pfizer monkey virus constitutive transport element. Journal of Virology. 74: 5863-71. PMID 10846066 DOI: 10.1128/Jvi.74.13.5863-5871.2000  0.499
1999 Truant R, Kang Y, Cullen BR. The human tap nuclear RNA export factor contains a novel transportin-dependent nuclear localization signal that lacks nuclear export signal function. The Journal of Biological Chemistry. 274: 32167-71. PMID 10542253 DOI: 10.1074/Jbc.274.45.32167  0.492
1999 Kang Y, Bogerd HP, Yang J, Cullen BR. Analysis of the RNA binding specificity of the human tap protein, a constitutive transport element-specific nuclear RNA export factor. Virology. 262: 200-9. PMID 10489353 DOI: 10.1006/Viro.1999.9906  0.485
1999 Kang Y, Cullen BR. The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences. Genes & Development. 13: 1126-39. PMID 10323864 DOI: 10.1101/Gad.13.9.1126  0.501
1998 Kang Y, Cullen BR. Derivation and functional characterization of a consensus DNA binding sequence for the tas transcriptional activator of simian foamy virus type 1. Journal of Virology. 72: 5502-9. PMID 9621006 DOI: 10.1128/Jvi.72.7.5502-5509.1998  0.475
1998 Kang Y, Blair WS, Cullen BR. Identification and functional characterization of a high-affinity Bel-1 DNA binding site located in the human foamy virus internal promoter. Journal of Virology. 72: 504-11. PMID 9420252 DOI: 10.1128/Jvi.72.1.504-511.1998  0.492
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