Gregor Krings, Ph.D. - Publications

Affiliations: 
2008 Medical University of South Carolina, Charleston, SC, United States 
Area:
Molecular Biology, Cell Biology, Microbiology Biology

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kang T, Yau C, Wong CK, Sanborn JZ, Newton Y, Vaske C, Benz SC, Krings G, Camarda R, Henry JE, Stuart J, Powell M, Benz CC. A risk-associated Active transcriptome phenotype expressed by histologically normal human breast tissue and linked to a pro-tumorigenic adipocyte population. Breast Cancer Research : Bcr. 22: 81. PMID 32736587 DOI: 10.1186/S13058-020-01322-6  0.359
2020 Mukhtar RA, Krings G, Chen YY, Mamounas ME, Fahrner-Scott K, Wong J, Alvarado M, Ewing C, Esserman LJ, Rugo H. Mitotic score and pleomorphic histology in invasive lobular carcinoma of the breast: impact on disease-free survival. Breast Cancer Research and Treatment. PMID 32240457 DOI: 10.1007/S10549-020-05606-5  0.308
2020 Beca F, Krings G, Chen YY, Hosfield EM, Vohra P, Sibley RK, Troxell ML, West RB, Allison KH, Bean GR. Primary mammary angiosarcomas harbor frequent mutations in KDR and PIK3CA and show evidence of distinct pathogenesis. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 32123305 DOI: 10.1038/S41379-020-0511-6  0.394
2020 Venters SJ, Wolf DM, Brown-Swigart L, Yau C, Delson AL, Parker B, Balassanian R, Carter J, Chen Y, Cole K, Khazai L, Klein M, Kokh D, Krings G, Sahoo S, et al. Abstract P6-10-02: Assessing biomarkers to inform treatment de-escalation: Mid-treatment biopsy cellularity predicts pCR in the I-SPY 2 Trial Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P6-10-02  0.336
2020 Benz CC, Kang T, Yau C, Wong C, Newton Y, Vaske C, Benz SC, Krings G, Camarda R, Henry JE, Stuart J, Powell M. Abstract P3-08-20: The normal breastActivetranscriptome associated with future breast cancer risk is driven by a dysregulated adipocyte microenvironment Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P3-08-20  0.328
2020 Osdoit M, Yau C, Symmans WF, Boughey JC, Asare SM, Balassanian R, Carter JM, Chen Y, Cole K, Khazai L, Klein M, Kokh D, Krings G, Sahoo S, Ahrendt G, et al. Abstract P3-08-16: The impact of residual ductal carcinoma in situ on breast cancer recurrence in the neoadjuvant I-SPY2 TRIAL Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P3-08-16  0.356
2020 Yau C, DeMichele A, Symmans WF, Pusztai L, Yee D, Clark AS, Hatzis C, Matthews JB, Carter J, Chen Y, Cole K, Khazai L, Klein M, Kokh D, Krings G, et al. Abstract P2-20-02: Site of recurrence after neoadjuvant therapy: Clues to biology and impact on endpoints Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P2-20-02  0.308
2019 Harrison BT, Fowler E, Krings G, Chen YY, Bean GR, Vincent-Salomon A, Fuhrmann L, Barnick SE, Chen B, Hosfield EM, Hornick JL, Schnitt SJ. Pan-TRK Immunohistochemistry: A Useful Diagnostic Adjunct For Secretory Carcinoma of the Breast. The American Journal of Surgical Pathology. PMID 31498178 DOI: 10.1097/Pas.0000000000001366  0.364
2019 Kang T, Yau C, Benz S, Krings G, Camarda R, Henry JE, Powell M, Benz CC. Abstract 3314: Normal breast tissue at risk for cancer development: A breast cancer initiating role for mammary adipocytes Cancer Research. 79: 3314-3314. DOI: 10.1158/1538-7445.Am2019-3314  0.35
2018 Shamir ER, Chen YY, Chu T, Pekmezci M, Rabban JT, Krings G. Pleomorphic and Florid Lobular Carcinoma in Situ Variants of the Breast: A Clinicopathologic Study of 85 Cases With and Without Invasive Carcinoma From a Single Academic Center. The American Journal of Surgical Pathology. PMID 30489319 DOI: 10.1097/Pas.0000000000001191  0.331
2018 Bean GR, Krings G, Otis CN, Solomon DA, García JJ, van Zante A, Camelo-Piragua S, Ziffle JV, Chen YY. CRTC1-MAML2 Fusion in Mucoepidermoid Carcinoma of the Breast. Histopathology. PMID 30380176 DOI: 10.1111/His.13779  0.376
2018 Shamir ER, Devine WP, Pekmezci M, Umetsu SE, Krings G, Federman S, Cho SJ, Saunders TA, Jen KY, Bergsland E, Jones K, Kim GE, Kakar S, Chiu CY, Joseph NM. Identification of high-risk human papillomavirus and Rb/E2F pathway genomic alterations in mutually exclusive subsets of colorectal neuroendocrine carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 30237525 DOI: 10.1038/S41379-018-0131-6  0.307
2018 Krings G, Chen YY. Genomic profiling of metaplastic breast carcinomas reveals genetic heterogeneity and relationship to ductal carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 29946183 DOI: 10.1038/S41379-018-0081-Z  0.351
2018 Cohen JN, Sabnis AJ, Krings G, Cho SJ, Horvai AE, Davis JL. EWSR1-NFATC2 Gene Fusion in a Soft Tissue Tumor with Epithelioid Round Cell Morphology and Abundant Stroma: A Case Report and Review of the Literature. Human Pathology. PMID 29626598 DOI: 10.1016/J.Humpath.2018.03.020  0.301
2018 Lindström LS, Yau C, Czene K, Thompson CK, Hoadley KA, Van't Veer LJ, Balassanian R, Bishop JW, Carpenter PM, Chen YY, Datnow B, Hasteh F, Krings G, Lin F, Zhang Y, et al. Intratumor Heterogeneity of the Estrogen Receptor and the Long-term Risk of Fatal Breast Cancer. Journal of the National Cancer Institute. PMID 29361175 DOI: 10.1093/Jnci/Djx270  0.326
2018 Park J, Thomas S, Zhong AY, Wolfe AR, Krings G, Terranova-Barberio M, Pawlowska N, Benet LZ, Munster PN. Local delivery of hormonal therapy with silastic tubing for prevention and treatment of breast cancer. Scientific Reports. 8: 92. PMID 29311658 DOI: 10.1038/S41598-017-18436-1  0.354
2018 Benz C, Yau C, Benz S, Krings G, Powell M. Abstract P3-10-05: Normal breast biopsies reveal an "active" transcriptome associating with higher breast cancer risk (Gail) scores and increased IGF-1 growth factor expression Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P3-10-05  0.354
2018 Camarda R, Williams J, Malkov S, Zimmerman LJ, Manning S, Aran D, Beardsley A, Mark DVd, Haren Jv, Chen Y, Berdan C, Louie S, Mahieu C, Winkler J, Willey E, ... ... Krings G, et al. Abstract 2398: Tumor cell-adipocyte gap junctions activate lipolysis in breast cancer Cancer Research. 78: 2398-2398. DOI: 10.1158/1538-7445.Am2018-2398  0.381
2018 Mamounas M, Wong J, Fahrner-Scott K, Chen YY, Krings G, Ewing C, Esserman L, Alvarado M, Rugo H, Mukhtar R. The impact of mitotic score versus pleomorphic subtype on disease free survival in invasive lobular carcinoma of the breast European Journal of Cancer. 92. DOI: 10.1016/S0959-8049(18)30619-1  0.32
2017 Terranova-Barberio M, Thomas S, Ali N, Pawlowska N, Park J, Krings G, Rosenblum MD, Budillon A, Munster PN. HDAC inhibition potentiates immunotherapy in triple negative breast cancer. Oncotarget. 8: 114156-114172. PMID 29371976 DOI: 10.18632/Oncotarget.23169  0.361
2017 Aran D, Camarda R, Odegaard J, Paik H, Oskotsky B, Krings G, Goga A, Sirota M, Butte AJ. Comprehensive analysis of normal adjacent to tumor transcriptomes. Nature Communications. 8: 1077. PMID 29057876 DOI: 10.1038/S41467-017-01027-Z  0.309
2017 Bartelink IH, Prideaux B, Krings G, Wilmes L, Lee PRE, Bo P, Hann B, Coppé JP, Heditsian D, Swigart-Brown L, Jones EF, Magnitsky S, Keizer RJ, de Vries N, Rosing H, et al. Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors. Breast Cancer Research : Bcr. 19: 107. PMID 28893315 DOI: 10.1186/S13058-017-0896-4  0.348
2017 Krings G, McIntire P, Shin SJ. Myofibroblastic, fibroblastic and myoid lesions of the breast. Seminars in Diagnostic Pathology. PMID 28751104 DOI: 10.1053/J.Semdp.2017.05.010  0.332
2017 Krings G, Bean GR, Chen YY. Fibroepithelial lesions; The WHO spectrum. Seminars in Diagnostic Pathology. PMID 28688536 DOI: 10.1053/J.Semdp.2017.05.006  0.317
2017 Krings G, Joseph NM, Bean GR, Solomon D, Onodera C, Talevich E, Yeh I, Grenert JP, Hosfield E, Crawford ED, Jordan RC, van Zante A, Zaloudek C, Shin SJ, Chen YY. Genomic profiling of breast secretory carcinomas reveals distinct genetics from other breast cancers and similarity to mammary analog secretory carcinomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 28548128 DOI: 10.1038/Modpathol.2017.32  0.398
2017 Korn WM, Yey I, Van Ziffle J, Grenert JP, Joseph N, Solomon DA, Laurance M, Talevich E, Onodera C, Krings G, Stohr BA, Blanco A, Bastian BC. Targeted next-generation DNA sequencing of paired tumor and normal DNA to reveal frequent actionable germline alterations. Journal of Clinical Oncology. 35: 11575-11575. DOI: 10.1200/Jco.2017.35.15_Suppl.11575  0.364
2016 Heng YJ, Lester SC, Tse GM, Factor RE, Allison KH, Collins LC, Chen YY, Jensen KC, Johnson NB, Jeong JC, Punjabi R, Shin SJ, Singh K, Krings G, Eberhard DA, et al. The molecular basis of breast cancer pathological phenotypes. The Journal of Pathology. PMID 27861902 DOI: 10.1002/Path.4847  0.37
2016 Campbell MJ, Baehner F, O'Meara T, Ojukwu E, Han B, Mukhtar R, Tandon V, Endicott M, Zhu Z, Wong J, Krings G, Au A, Gray JW, Esserman L. Characterizing the immune microenvironment in high-risk ductal carcinoma in situ of the breast. Breast Cancer Research and Treatment. PMID 27785654 DOI: 10.1007/S10549-016-4036-0  0.328
2016 Ballard M, Jalikis F, Krings G, Schmidt RA, Chen YY, Rendi MH, Dintzis SM, Jensen KC, West RB, Sibley RK, Troxell ML, Allison KH. 'Non-classical' HER2 FISH results in breast cancer: a multi-institutional study. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 27739440 DOI: 10.1038/Modpathol.2016.175  0.328
2016 Liu SY, Joseph NM, Ravindranathan A, Stohr BA, Greenland NY, Vohra P, Hosfield E, Yeh I, Talevich E, Onodera C, Van Ziffle JA, Grenert JP, Bastian BC, Chen YY, Krings G. Genomic profiling of malignant phyllodes tumors reveals aberrations in FGFR1 and PI-3 kinase/RAS signaling pathways and provides insights into intratumoral heterogeneity. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 27255162 DOI: 10.1038/Modpathol.2016.97  0.331
2016 Camarda R, Zhou AY, Kohnz RA, Balakrishnan S, Mahieu C, Anderton B, Eyob H, Kajimura S, Tward A, Krings G, Nomura DK, Goga A. Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. Nature Medicine. PMID 26950360 DOI: 10.1038/Nm.4055  0.35
2016 Myers SA, Peddada S, Chatterjee N, Freidreich T, Tomoda K, Krings G, Thomas S, Broeker M, Maynard J, Thomson M, Pollard K, Yamanaka S, Burlingame AL, Panning B. SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells. Elife. 5. PMID 26949256 DOI: 10.7554/Elife.10647  0.52
2016 Myers SA, Peddada S, Chatterjee N, Friedrich T, Tomoda K, Krings G, Thomas S, Maynard J, Broeker M, Thomson M, Pollard K, Yamanaka S, Burlingame AL, Panning B. Author response: SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells Elife. DOI: 10.7554/Elife.10647.033  0.525
2016 Goga A, Camarda R, Zhou A, Kohnz R, Balakrishnan S, Anderton B, Mahieu C, Eyob H, Krings G, Nomura D. Abstract PD3-05: Inhibition of fatty-acid oxidation as a therapy for triple-negative breast cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-Pd3-05  0.339
2016 Camarda R, Zhou AY, Kohnz RA, Balakrishnan S, Mahieu C, Anderton B, Eyob H, Kajimura S, Tward A, Krings G, Nomura DK, Goga A. Abstract 2673: Inhibition of fatty-acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer Cancer Research. 76: 2673-2673. DOI: 10.1158/1538-7445.Am2016-2673  0.345
2016 Drukker K, Malkov S, Ávila J, Kerlikowske K, Joe BN, Krings G, Creasman J, Drukteinis JS, Pereira MM, Kazemi L, Shepherd J, Giger ML. Identification, segmentation, and characterization of microcalcifications on mammography Proceedings of Spie. 9785. DOI: 10.1117/12.2216274  0.343
2015 Bartelink IH, Prideaux B, Hann B, Krings G, Coppe J, Swigart-Brown L, Lee PRE, Esserman L, Yee D, Wolf D, Savic RM, Veer Lvt. Abstract P6-11-02: Spatial distribution of veliparib measured by matrix assisted laser desorption ionization mass spectrometry in triple negative breast cancer tumors Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P6-11-02  0.33
2015 Ng D, Krings G, Yau C, White K, Hou J, Chua A, Grenert JP, Chen Y. Abstract P3-06-28: Alterations in HER2 status and outcome following neoadjuvant chemotherapy in HER2-positive breast cancer (BC) Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P3-06-28  0.366
2015 Bartelink IH, Prideaux B, Krings G, Wilmes L, Lee PRE, Hann B, Coppé J, Heditsian D, Swigart-Brown L, Jones EF, Magnitsky S, Keizer R, Esserman L, Ruan W, Wu A, et al. Abstract C61: Non-homogeneous drug penetrance of veliparib measured in triple negative breast tumors Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-C61  0.321
2014 Prideaux B, Hann B, Krings G, Coppe JP, Brown Swigart L, Lee EP, Esserman L, Yee D, Wolf D, Savic RM. Spatial distribution of veliparib measured by matrix-assisted laser desorption ionization mass spectrometry in triple-negative breast cancer tumors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 161. PMID 28141099 DOI: 10.1200/Jco.2014.32.26_Suppl.161  0.327
2014 Krings G, Nystrom M, Mehdi I, Vohra P, Chen YY. Diagnostic utility and sensitivities of GATA3 antibodies in triple-negative breast cancer. Human Pathology. 45: 2225-32. PMID 25150746 DOI: 10.1016/J.Humpath.2014.06.022  0.342
2014 Mori M, Krings G, Chan L, Wolf D, Chen Y, Kerlikowske K, Tlsty TD, Coppe J, Matsuda N, Suzuki K, Nakamura S, van't Veer L. Predictive biomarkers of invasive carcinoma on excision in patients with a diagnosis of ductal carcinoma in situ of the breast by needle biopsy. Journal of Clinical Oncology. 32: e12029-e12029. DOI: 10.1200/Jco.2014.32.15_Suppl.E12029  0.342
2013 Mori M, Krings G, Chan L, Chen Y, Kerlikowske K, Tlsty T, Matsuda N, Suzuki K, Veer Lv. Abstract P5-16-04: Predictive biomarkers for invasion on final pathology in patients with preoperative diagnosis of ductal carcinoma in situ of the breast by needle biopsy Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P5-16-04  0.35
2008 Bastia D, Zzaman S, Krings G, Saxena M, Peng X, Greenberg MM. Replication termination mechanism as revealed by Tus-mediated polar arrest of a sliding helicase. Proceedings of the National Academy of Sciences of the United States of America. 105: 12831-6. PMID 18708526 DOI: 10.1073/Pnas.0805898105  0.569
2006 Krings G, Bastia D. Molecular architecture of a eukaryotic DNA replication terminus-terminator protein complex. Molecular and Cellular Biology. 26: 8061-74. PMID 16940176 DOI: 10.1128/Mcb.01102-06  0.571
2005 Krings G, Bastia D. Sap1p binds to Ter1 at the ribosomal DNA of Schizosaccharomyces pombe and causes polar replication fork arrest. The Journal of Biological Chemistry. 280: 39135-42. PMID 16195226 DOI: 10.1074/Jbc.M508996200  0.572
2004 Krings G, Bastia D. swi1- and swi3-dependent and independent replication fork arrest at the ribosomal DNA of Schizosaccharomyces pombe. Proceedings of the National Academy of Sciences of the United States of America. 101: 14085-90. PMID 15371597 DOI: 10.1073/Pnas.0406037101  0.573
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