| Year |
Citation |
Score |
| 2023 |
Toft PB, Yashiro H, Erion DM, Gillum MP, Bäckhed F, Arora T. Microbial dietary protein metabolism regulates GLP-1 mediated intestinal transit. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 37: e23201. PMID 37732618 DOI: 10.1096/fj.202300982R |
0.646 |
|
| 2021 |
Tamura YO, Sugama J, Iwasaki S, Sasaki M, Yasuno H, Aoyama K, Watanabe M, Erion DM, Yashiro H. Selective acetyl-CoA carboxylase 1 inhibitor improves hepatic steatosis and hepatic fibrosis in a pre-clinical NASH model. The Journal of Pharmacology and Experimental Therapeutics. PMID 34535562 DOI: 10.1124/jpet.121.000786 |
0.318 |
|
| 2021 |
Gutierrez JA, Liu W, Perez S, Xing G, Sonnenberg G, Kou K, Blatnik M, Allen R, Weng Y, Vera NB, Chidsey K, Bergman A, Somayaji V, Crowley C, Clasquin MF, ... ... Erion DM, et al. Pharmacologic inhibition of Ketohexokinase prevents fructose-induced metabolic dysfunction. Molecular Metabolism. 101196. PMID 33667726 DOI: 10.1016/j.molmet.2021.101196 |
0.348 |
|
| 2020 |
Matsumoto M, Yashiro H, Ogino H, Aoyama K, Nambu T, Nakamura S, Nishida M, Wang X, Erion DM, Kaneko M. Acetyl-CoA carboxylase 1 and 2 inhibition ameliorates steatosis and hepatic fibrosis in a MC4R knockout murine model of nonalcoholic steatohepatitis. Plos One. 15: e0228212. PMID 31990961 DOI: 10.1371/Journal.Pone.0228212 |
0.446 |
|
| 2018 |
Li MD, Vera NB, Yang Y, Zhang B, Ni W, Ziso-Qejvanaj E, Ding S, Zhang K, Yin R, Wang S, Zhou X, Fang EX, Xu T, Erion DM, Yang X. Adipocyte OGT governs diet-induced hyperphagia and obesity. Nature Communications. 9: 5103. PMID 30504766 DOI: 10.1038/S41467-018-07461-X |
0.368 |
|
| 2017 |
Corbit KC, Camporez JPG, Edmunds LR, Tran JL, Vera NB, Erion DM, Deo RC, Perry RJ, Shulman GI, Jurczak MJ, Weiss EJ. Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling. Diabetes. PMID 29203511 DOI: 10.2337/Db17-0524 |
0.728 |
|
| 2017 |
Mottillo EP, Desjardins EM, Fritzen AM, Zou VZ, Crane JD, Yabut JM, Kiens B, Erion DM, Lanba A, Granneman JG, Talukdar S, Steinberg GR. FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasis. Molecular Metabolism. 6: 471-481. PMID 28580278 DOI: 10.1016/J.Molmet.2017.04.001 |
0.433 |
|
| 2016 |
Di L, Riccardi K, Li Z, Brown JA, Gorgoglione MF, Niosi M, Gosset J, Huard K, Erion DM. Determination of Unbound Partition Coefficient (Kpuu) and in Vitro-in Vivo Extrapolation for SLC13A Transporter-Mediated Uptake. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 27417179 DOI: 10.1124/Dmd.116.071837 |
0.312 |
|
| 2016 |
Talukdar S, Zhou Y, Li D, Rossulek M, Dong J, Somayaji V, Weng Y, Clark R, Lanba A, Owen BM, Brenner MB, Trimmer JK, Gropp KE, Chabot JR, Erion DM, et al. A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects. Cell Metabolism. 23: 427-440. PMID 26959184 DOI: 10.1016/J.Cmet.2016.02.001 |
0.387 |
|
| 2016 |
Huard K, Gosset JR, Montgomery JI, Gilbert AM, Hayward MM, Magee TV, Cabral S, Uccello DP, Bahnck KB, Brown JA, Purkal J, Gorgoglione MF, Lanba A, Futatsugi K, Herr M, ... ... Erion DM, et al. Optimization of a dicarboxylic series for in vivo inhibition of citrate transport by the solute carrier 13 (SLC13) family. Journal of Medicinal Chemistry. PMID 26734723 DOI: 10.1021/Acs.Jmedchem.5B01752 |
0.318 |
|
| 2016 |
Erion DM, Park HJ, Lee HY. The role of lipids in the pathogenesis and treatment of type 2 diabetes and associated co-morbidities. Bmb Reports. PMID 26728273 DOI: 10.5483/Bmbrep.2016.49.3.268 |
0.526 |
|
| 2015 |
Wilson CG, Tran JL, Erion DM, Vera NB, Febbraio M, Weiss EJ. Hepatocyte-specific disruption of CD36 attenuates fatty liver and improves insulin sensitivity in HFD fed mice. Endocrinology. en20151866. PMID 26650570 DOI: 10.1210/En.2015-1866 |
0.449 |
|
| 2015 |
Khatun I, Clark RW, Vera NB, Kou K, Erion DM, Coskran T, Bobrowski WF, Okerberg C, Goodwin B. Characterization of a novel intestinal glycerol-3-phosphate acyltransferase pathway and its role in lipid homeostasis. The Journal of Biological Chemistry. PMID 26644473 DOI: 10.1074/Jbc.M115.683359 |
0.38 |
|
| 2015 |
Huard K, Brown J, Jones JC, Cabral S, Futatsugi K, Gorgoglione M, Lanba A, Vera NB, Zhu Y, Yan Q, Zhou Y, Vernochet C, Riccardi K, Wolford A, Pirman D, ... ... Erion DM, et al. Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5). Scientific Reports. 5: 17391. PMID 26620127 DOI: 10.1038/Srep17391 |
0.309 |
|
| 2015 |
Bernardo B, Lu M, Bandyopadhyay G, Li P, Zhou Y, Huang J, Levin N, Tomas EM, Calle RA, Erion DM, Rolph TP, Brenner M, Talukdar S. FGF21 does not require interscapular brown adipose tissue and improves liver metabolic profile in animal models of obesity and insulin-resistance. Scientific Reports. 5: 11382. PMID 26153793 DOI: 10.1038/Srep11382 |
0.509 |
|
| 2014 |
Erion DM, Lapworth A, Amor PA, Bai G, Vera NB, Clark RW, Yan Q, Zhu Y, Ross TT, Purkal J, Gorgoglione M, Zhang G, Bonato V, Baker L, Barucci N, et al. The hepatoselective glucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats. Plos One. 9: e97139. PMID 24858947 DOI: 10.1371/Journal.Pone.0097139 |
0.556 |
|
| 2014 |
Madiraju AK, Erion DM, Rahimi Y, Zhang XM, Braddock DT, Albright RA, Prigaro BJ, Wood JL, Bhanot S, MacDonald MJ, Jurczak MJ, Camporez JP, Lee HY, Cline GW, Samuel VT, et al. Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase. Nature. 510: 542-6. PMID 24847880 DOI: 10.1038/Nature13270 |
0.751 |
|
| 2014 |
Hall AM, Soufi N, Chambers KT, Chen Z, Schweitzer GG, McCommis KS, Erion DM, Graham MJ, Su X, Finck BN. Abrogating monoacylglycerol acyltransferase activity in liver improves glucose tolerance and hepatic insulin signaling in obese mice. Diabetes. 63: 2284-96. PMID 24595352 DOI: 10.2337/Db13-1502 |
0.572 |
|
| 2014 |
Neuschäfer-Rube F, Lieske S, Kuna M, Henkel J, Perry RJ, Erion DM, Pesta D, Willmes DM, Brachs S, von Loeffelholz C, Tolkachov A, Schupp M, Pathe-Neuschäfer-Rube A, Pfeiffer AF, Shulman GI, et al. The mammalian INDY homolog is induced by CREB in a rat model of type 2 diabetes. Diabetes. 63: 1048-57. PMID 24222346 DOI: 10.2337/Db13-0749 |
0.65 |
|
| 2013 |
Vatner DF, Weismann D, Beddow SA, Kumashiro N, Erion DM, Liao XH, Grover GJ, Webb P, Phillips KJ, Weiss RE, Bogan JS, Baxter J, Shulman GI, Samuel VT. Thyroid hormone receptor-β agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways. American Journal of Physiology. Endocrinology and Metabolism. 305: E89-100. PMID 23651850 DOI: 10.1152/Ajpendo.00573.2012 |
0.769 |
|
| 2013 |
Erion DM, Kotas ME, McGlashon J, Yonemitsu S, Hsiao JJ, Nagai Y, Iwasaki T, Murray SF, Bhanot S, Cline GW, Samuel VT, Shulman GI, Gillum MP. cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 2 (CRTC2) promotes glucagon clearance and hepatic amino acid catabolism to regulate glucose homeostasis. The Journal of Biological Chemistry. 288: 16167-76. PMID 23595987 DOI: 10.1074/Jbc.M113.460246 |
0.783 |
|
| 2013 |
Kumashiro N, Yoshimura T, Cantley JL, Majumdar SK, Guebre-Egziabher F, Kursawe R, Vatner DF, Fat I, Kahn M, Erion DM, Zhang XM, Zhang D, Manchem VP, Bhanot S, Gerhard GS, et al. Role of patatin-like phospholipase domain-containing 3 on lipid-induced hepatic steatosis and insulin resistance in rats Hepatology. 57: 1763-1772. PMID 23175050 DOI: 10.1002/Hep.26170 |
0.757 |
|
| 2013 |
Erion DM, Popov V, Hsiao JJ, Vatner D, Mitchell K, Yonemitsu S, Nagai Y, Kahn M, Gillum MP, Dong J, Murray SF, Manchem VP, Bhanot S, Cline GW, Shulman GI, et al. The role of the carbohydrate response element-binding protein in male fructose-fed rats Endocrinology. 154: 36-44. PMID 23161873 DOI: 10.1210/En.2012-1725 |
0.804 |
|
| 2012 |
Brown WH, Gillum MP, Lee HY, Camporez JP, Zhang XM, Jeong JK, Alves TC, Erion DM, Guigni BA, Kahn M, Samuel VT, Cravatt BF, Diano S, Shulman GI. Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism. Proceedings of the National Academy of Sciences of the United States of America. 109: 14966-71. PMID 22912404 DOI: 10.1073/Pnas.1212887109 |
0.777 |
|
| 2011 |
Gillum MP, Kotas ME, Erion DM, Kursawe R, Chatterjee P, Nead KT, Muise ES, Hsiao JJ, Frederick DW, Yonemitsu S, Banks AS, Qiang L, Bhanot S, Olefsky JM, Sears DD, et al. SirT1 regulates adipose tissue inflammation. Diabetes. 60: 3235-45. PMID 22110092 DOI: 10.2337/Db11-0616 |
0.669 |
|
| 2011 |
Kumashiro N, Erion DM, Zhang D, Kahn M, Beddow SA, Chu X, Still CD, Gerhard GS, Han X, Dziura J, Petersen KF, Samuel VT, Shulman GI. Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease. Proceedings of the National Academy of Sciences of the United States of America. 108: 16381-5. PMID 21930939 DOI: 10.1073/Pnas.1113359108 |
0.744 |
|
| 2011 |
Horvath TL, Erion DM, Elsworth JD, Roth RH, Shulman GI, Andrews ZB. GPA protects the nigrostriatal dopamine system by enhancing mitochondrial function. Neurobiology of Disease. 43: 152-62. PMID 21406233 DOI: 10.1016/J.Nbd.2011.03.005 |
0.476 |
|
| 2011 |
Weismann D, Erion DM, Ignatova-Todorava I, Nagai Y, Stark R, Hsiao JJ, Flannery C, Birkenfeld AL, May T, Kahn M, Zhang D, Yu XX, Murray SF, Bhanot S, Monia BP, et al. Knockdown of the gene encoding Drosophila tribbles homologue 3 (Trib3) improves insulin sensitivity through peroxisome proliferator-activated receptor-γ (PPAR-γ) activation in a rat model of insulin resistance Diabetologia. 54: 935-944. PMID 21190014 DOI: 10.1007/S00125-010-1984-5 |
0.708 |
|
| 2011 |
Gillum MP, Erion DM, Shulman GI. Sirtuin-1 regulation of mammalian metabolism. Trends in Molecular Medicine. 17: 8-13. PMID 20971038 DOI: 10.1016/J.Molmed.2010.09.005 |
0.725 |
|
| 2010 |
Erion DM, Shulman GI. Diacylglycerol-mediated insulin resistance. Nature Medicine. 16: 400-2. PMID 20376053 DOI: 10.1038/Nm0410-400 |
0.573 |
|
| 2010 |
Andrews ZB, Erion DM, Beiler R, Choi CS, Shulman GI, Horvath TL. Uncoupling protein-2 decreases the lipogenic actions of ghrelin. Endocrinology. 151: 2078-86. PMID 20189996 DOI: 10.1210/En.2009-0850 |
0.525 |
|
| 2009 |
Erion DM, Ignatova ID, Yonemitsu S, Nagai Y, Chatterjee P, Weismann D, Hsiao JJ, Zhang D, Iwasaki T, Stark R, Flannery C, Kahn M, Carmean CM, Yu XX, Murray SF, et al. Prevention of Hepatic Steatosis and Hepatic Insulin Resistance by Knockdown of cAMP Response Element-Binding Protein Cell Metabolism. 10: 499-506. PMID 19945407 DOI: 10.1016/J.Cmet.2009.10.007 |
0.772 |
|
| 2009 |
Andrews ZB, Erion D, Beiler R, Liu ZW, Abizaid A, Zigman J, Elsworth JD, Savitt JM, DiMarchi R, Tschoep M, Roth RH, Gao XB, Horvath TL. Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14057-65. PMID 19906954 DOI: 10.1523/Jneurosci.3890-09.2009 |
0.309 |
|
| 2009 |
Erion DM, Yonemitsu S, Nie Y, Nagai Y, Gillum MP, Hsiao JJ, Iwasaki T, Stark R, Weismann D, Yu XX, Murray SF, Bhanot S, Monia BP, Horvath TL, Gao Q, et al. SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats. Proceedings of the National Academy of Sciences of the United States of America. 106: 11288-93. PMID 19549853 DOI: 10.1073/Pnas.0812931106 |
0.807 |
|
| 2009 |
Nie Y, Erion DM, Yuan Z, Dietrich M, Shulman GI, Horvath TL, Gao Q. STAT3 inhibition of gluconeogenesis is downregulated by SirT1. Nature Cell Biology. 11: 492-500. PMID 19295512 DOI: 10.1038/Ncb1857 |
0.535 |
|
| 2009 |
Nagai Y, Yonemitsu S, Erion DM, Iwasaki T, Stark R, Weismann D, Dong J, Zhang D, Jurczak MJ, Löffler MG, Cresswell J, Yu XX, Murray SF, Bhanot S, Monia BP, et al. The role of peroxisome proliferator-activated receptor gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance. Cell Metabolism. 9: 252-64. PMID 19254570 DOI: 10.1016/J.Cmet.2009.01.011 |
0.72 |
|
| 2008 |
Gillum MP, Zhang D, Zhang XM, Erion DM, Jamison RA, Choi C, Dong J, Shanabrough M, Duenas HR, Frederick DW, Hsiao JJ, Horvath TL, Lo CM, Tso P, Cline GW, et al. N-acylphosphatidylethanolamine, a gut- derived circulating factor induced by fat ingestion, inhibits food intake. Cell. 135: 813-24. PMID 19041747 DOI: 10.1016/J.Cell.2008.10.043 |
0.684 |
|
| 2008 |
Andrews ZB, Liu ZW, Walllingford N, Erion DM, Borok E, Friedman JM, Tschöp MH, Shanabrough M, Cline G, Shulman GI, Coppola A, Gao XB, Horvath TL, Diano S. UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals. Nature. 454: 846-51. PMID 18668043 DOI: 10.1038/Nature07181 |
0.466 |
|
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