Hailiang Huang, Ph.D. - Publications

Affiliations: 
2012 Johns Hopkins University, Baltimore, MD 
Area:
Bioinformatics Biology, Biomedical Engineering, Systematic Biology

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Song W, Kossowsky J, Torous J, Chen CY, Huang H, Mukamal KJ, Berde CB, Bates DW, Wright A. Genome-wide association analysis of opioid use disorder: A novel approach using clinical data. Drug and Alcohol Dependence. 217: 108276. PMID 32961455 DOI: 10.1016/J.Drugalcdep.2020.108276  0.332
2020 Zhao B, Chen Y, Li M, Zhou J, Teng Z, Chen J, Zhao X, Wu H, Bai T, Mao S, Fang F, Chu W, Huang H, Huai C, Shen L, et al. Novel susceptibility loci for A(H7N9) infection identified by next generation sequencing and functional analysis. Scientific Reports. 10: 11768. PMID 32678187 DOI: 10.1038/S41598-020-68675-Y  0.31
2020 Wu Y, Cao H, Baranova A, Huang H, Li S, Cai L, Rao S, Dai M, Xie M, Dou Y, Hao Q, Zhu L, Zhang X, Yao Y, Zhang F, et al. Correction: Multi-trait analysis for genome-wide association study of five psychiatric disorders. Translational Psychiatry. 10: 234. PMID 32665544 DOI: 10.1038/S41398-020-00924-0  0.326
2020 Wu Y, Cao H, Baranova A, Huang H, Li S, Cai L, Rao S, Dai M, Xie M, Dou Y, Hao Q, Zhu L, Zhang X, Yao Y, Xu M, et al. Multi-trait analysis for genome-wide association study of five psychiatric disorders. Translational Psychiatry. 10: 209. PMID 32606422 DOI: 10.1038/S41398-020-00902-6  0.318
2020 Song W, Torous J, Kossowsky J, Chen CY, Huang H, Wright A. Genome-wide association analysis of insomnia using data from Partners Biobank. Scientific Reports. 10: 6928. PMID 32332799 DOI: 10.1038/S41598-020-63792-0  0.376
2020 Li M, Shen L, Chen L, Huai C, Huang H, Wu X, Yang C, Ma J, Zhou W, Du H, Fan L, He L, Wan C, Qin S. Novel genetic susceptibility loci identified by family based whole exome sequencing in Han Chinese schizophrenia patients. Translational Psychiatry. 10: 5. PMID 32066673 DOI: 10.1038/S41398-020-0708-Y  0.366
2019 Lam M, Chen CY, Li Z, Martin AR, Bryois J, Ma X, Gaspar H, Ikeda M, Benyamin B, Brown BC, Liu R, Zhou W, Guan L, Kamatani Y, Kim SW, ... ... Huang H, et al. Comparative genetic architectures of schizophrenia in East Asian and European populations. Nature Genetics. PMID 31740837 DOI: 10.1038/S41588-019-0512-X  0.345
2019 Peterson RE, Kuchenbaecker K, Walters RK, Chen CY, Popejoy AB, Periyasamy S, Lam M, Iyegbe C, Strawbridge RJ, Brick L, Carey CE, Martin AR, Meyers JL, Su J, Chen J, ... ... Huang H, et al. Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations. Cell. PMID 31607513 DOI: 10.1016/J.Cell.2019.08.051  0.328
2019 Lam M, Awasthi S, Watson HJ, Goldstein J, Panagiotaropoulou G, Trubetskoy V, Karlsson R, Frei O, Fan CC, De Witte W, Mota NR, Mullins N, Brügger K, Lee H, Wray N, ... ... Huang H, et al. RICOPILI: Rapid Imputation for COnsortias PIpeLIne. Bioinformatics (Oxford, England). PMID 31393554 DOI: 10.1093/Bioinformatics/Btz633  0.331
2019 Smillie CS, Biton M, Ordovas-Montanes J, Sullivan KM, Burgin G, Graham DB, Herbst RH, Rogel N, Slyper M, Waldman J, Sud M, Andrews E, Velonias G, Haber AL, Jagadeesh K, ... ... Huang H, et al. Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis. Cell. 178: 714-730.e22. PMID 31348891 DOI: 10.1016/J.Cell.2019.06.029  0.345
2019 Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, ... ... Huang H, et al. Identification of common genetic risk variants for autism spectrum disorder. Nature Genetics. PMID 30804558 DOI: 10.1038/S41588-019-0344-8  0.371
2019 Huang H, Lam M, Chen C, Martin A, Li Z, Ripke S, O'Donovan M, Daly M. Using Genetic Diversity From East Asia To Improve The Biological Insight Into Schizophrenia European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.002  0.313
2018 Demontis D, Walters RK, Martin J, Mattheisen M, Als TD, Agerbo E, Baldursson G, Belliveau R, Bybjerg-Grauholm J, Bækvad-Hansen M, Cerrato F, Chambert K, Churchhouse C, Dumont A, Eriksson N, ... ... Huang H, et al. Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder. Nature Genetics. PMID 30478444 DOI: 10.1038/S41588-018-0269-7  0.3
2018 Song W, Huang H, Zhang CZ, Bates DW, Wright A. Using whole genome scores to compare three clinical phenotyping methods in complex diseases. Scientific Reports. 8: 11360. PMID 30054501 DOI: 10.1038/S41598-018-29634-W  0.345
2018 Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, ... ... Huang H, et al. Analysis of shared heritability in common disorders of the brain. Science (New York, N.Y.). 360. PMID 29930110 DOI: 10.1126/Science.Aap8757  0.3
2018 Rivas MA, Avila BE, Koskela J, Huang H, Stevens C, Pirinen M, Haritunians T, Neale BM, Kurki M, Ganna A, Graham D, Glaser B, Peter I, Atzmon G, Barzilai N, et al. Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population. Plos Genetics. 14: e1007329. PMID 29795570 DOI: 10.1371/Journal.Pgen.1007329  0.361
2017 Sanders SJ, Neale BM, Huang H, Werling DM, An JY, Dong S, Abecasis G, Arguello PA, Blangero J, Boehnke M, Daly MJ, Eggan K, Geschwind DH, Glahn DC, Goldstein DB, et al. Whole genome sequencing in psychiatric disorders: the WGSPD consortium. Nature Neuroscience. 20: 1661-1668. PMID 29184211 DOI: 10.1038/S41593-017-0017-9  0.323
2017 Huang H, Duggal P, Thio CL, Latanich R, Goedert JJ, Mangia A, Cox AL, Kirk GD, Mehta S, Aneja J, Alric L, Donfield SM, Cramp ME, Khakoo SI, Tobler LH, et al. Fine-mapping of genetic loci driving spontaneous clearance of hepatitis C virus infection. Scientific Reports. 7: 15843. PMID 29158528 DOI: 10.1038/S41598-017-16011-2  0.323
2017 Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, ... ... Huang H, et al. Discovery of stimulation-responsive immune enhancers with CRISPR activation. Nature. PMID 28854172 DOI: 10.1038/Nature23875  0.365
2017 Shooshtari P, Huang H, Cotsapas C. Integrative Genetic and Epigenetic Analysis Uncovers Regulatory Mechanisms of Autoimmune Disease. American Journal of Human Genetics. 101: 75-86. PMID 28686857 DOI: 10.1016/J.Ajhg.2017.06.001  0.363
2017 Huang H, Fang M, Jostins L, Umićević Mirkov M, Boucher G, Anderson CA, Andersen V, Cleynen I, Cortes A, Crins F, D'Amato M, Deffontaine V, Dmitrieva J, Docampo E, Elansary M, et al. Fine-mapping inflammatory bowel disease loci to single-variant resolution. Nature. PMID 28658209 DOI: 10.1038/Nature22969  0.378
2017 Lam M, Huang H. Psychiatric Genomics Consortium – Genetic Architecture Of Schizophrenia In Asian Populations European Neuropsychopharmacology. 27. DOI: 10.1016/J.Euroneuro.2016.09.581  0.32
2016 Tylee DS, Hess JL, Quinn TP, Barve R, Huang H, Zhang-James Y, Chang J, Stamova BS, Sharp FR, Hertz-Picciotto I, Faraone SV, Kong SW, Glatt SJ. Blood transcriptomic comparison of individuals with and without autism spectrum disorder: A combined-samples mega-analysis. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 27862943 DOI: 10.1002/Ajmg.B.32511  0.329
2016 Gormley P, Anttila V, Winsvold BS, Palta P, Esko T, Pers TH, Farh KH, Cuenca-Leon E, Muona M, Furlotte NA, Kurth T, Ingason A, McMahon G, Ligthart L, Terwindt GM, ... ... Huang H, et al. Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Nature Genetics. 48: 1296. PMID 27681292 DOI: 10.1038/Ng1016-1296C  0.321
2016 Peloquin JM, Goel G, Kong L, Huang H, Haritunians T, Sartor RB, Daly MJ, Newberry RD, McGovern DP, Yajnik V, Lira SA, Xavier RJ. Characterization of candidate genes in inflammatory bowel disease-associated risk loci. Jci Insight. 1: e87899. PMID 27668286 DOI: 10.1172/Jci.Insight.87899  0.356
2016 Gormley P, Anttila V, Winsvold BS, Palta P, Esko T, Pers TH, Farh KH, Cuenca-Leon E, Muona M, Furlotte NA, Kurth T, Ingason A, McMahon G, Ligthart L, Terwindt GM, ... ... Huang H, et al. Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Nature Genetics. PMID 27322543 DOI: 10.1038/Ng.3598  0.384
2016 Lassen KG, McKenzie CI, Mari M, Murano T, Begun J, Baxt LA, Goel G, Villablanca EJ, Kuo SY, Huang H, Macia L, Bhan AK, Batten M, Daly MJ, Reggiori F, et al. Genetic Coding Variant in GPR65 Alters Lysosomal pH and Links Lysosomal Dysfunction with Colitis Risk. Immunity. PMID 27287411 DOI: 10.1016/J.Immuni.2016.05.007  0.354
2016 Peloquin J, Goel G, Huang H, Haritunians T, Sartor R, Daly M, Newberry R, McGovern D, Lira S, Xavier R. O-002 Genes in IBD-Associated Risk Loci Demonstrate Genotype-, Tissue-, and Inflammation-Specific Patterns of Expression in Terminal Ileum and Colon Mucosal Tissue. Inflammatory Bowel Diseases. 22: S1. PMID 26849719 DOI: 10.1097/01.Mib.0000480040.50582.81  0.374
2015 Liu JZ, van Sommeren S, Huang H, Ng SC, Alberts R, Takahashi A, Ripke S, Lee JC, Jostins L, Shah T, Abedian S, Cheon JH, Cho J, Daryani NE, Franke L, et al. Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. Nature Genetics. PMID 26192919 DOI: 10.1038/Ng.3359  0.378
2015 Betz RC, Petukhova L, Ripke S, Huang H, Menelaou A, Redler S, Becker T, Heilmann S, Yamany T, Duvic M, Hordinsky M, Norris D, Price VH, Mackay-Wiggan J, de Jong A, et al. Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci. Nature Communications. 6: 5966. PMID 25608926 DOI: 10.1038/Ncomms6966  0.388
2015 Goyette P, Boucher G, Mallon D, Ellinghaus E, Jostins L, Huang H, Ripke S, Gusareva ES, Annese V, Hauser SL, Oksenberg JR, Thomsen I, Leslie S, et al. High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis. Nature Genetics. 47: 172-9. PMID 25559196 DOI: 10.1038/Ng.3176  0.332
2014 Knights D, Silverberg MS, Weersma RK, Gevers D, Dijkstra G, Huang H, Tyler AD, van Sommeren S, Imhann F, Stempak JM, Huang H, Vangay P, Al-Ghalith GA, Russell C, Sauk J, et al. Complex host genetics influence the microbiome in inflammatory bowel disease. Genome Medicine. 6: 107. PMID 25587358 DOI: 10.1186/S13073-014-0107-1  0.406
2014 Goldstein JI, Jarskog LF, Hilliard C, Alfirevic A, Duncan L, Fourches D, Huang H, Lek M, Neale BM, Ripke S, Shianna K, Szatkiewicz JP, Tropsha A, van den Oord EJ, Cascorbi I, et al. Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles. Nature Communications. 5: 4757. PMID 25187353 DOI: 10.1038/Ncomms5757  0.334
2014 Arking DE, Pulit SL, Crotti L, van der Harst P, Munroe PB, Koopmann TT, Sotoodehnia N, Rossin EJ, Morley M, Wang X, Johnson AD, Lundby A, Gudbjartsson DF, Noseworthy PA, Eijgelsheim M, ... ... Huang H, et al. Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nature Genetics. 46: 826-36. PMID 24952745 DOI: 10.1038/Ng.3014  0.583
2013 Chanda P, Huang H, Arking DE, Bader JS. Fast association tests for genes with FAST. Plos One. 8: e68585. PMID 23935874 DOI: 10.1371/Journal.Pone.0068585  0.565
2013 Huang H, Tata S, Prill RJ. BlueSNP: R package for highly scalable genome-wide association studies using Hadoop clusters. Bioinformatics (Oxford, England). 29: 135-6. PMID 23202745 DOI: 10.1093/Bioinformatics/Bts647  0.318
2011 Huang H, Chanda P, Alonso A, Bader JS, Arking DE. Gene-based tests of association. Plos Genetics. 7: e1002177. PMID 21829371 DOI: 10.1371/Journal.Pgen.1002177  0.6
2010 Zhong J, Krawczyk SA, Chaerkady R, Huang H, Goel R, Bader JS, Wong GW, Corkey BE, Pandey A. Temporal profiling of the secretome during adipogenesis in humans. Journal of Proteome Research. 9: 5228-38. PMID 20707391 DOI: 10.1021/Pr100521C  0.531
2009 Huang H, Maertens AM, Hyland EM, Dai J, Norris A, Boeke JD, Bader JS. HistoneHits: a database for histone mutations and their phenotypes. Genome Research. 19: 674-81. PMID 19218532 DOI: 10.1101/Gr.083402.108  0.541
2009 Huang H, Bader JS. Precision and recall estimates for two-hybrid screens. Bioinformatics (Oxford, England). 25: 372-8. PMID 19091773 DOI: 10.1093/Bioinformatics/Btn640  0.527
2008 Dai J, Hyland EM, Yuan DS, Huang H, Bader JS, Boeke JD. Probing nucleosome function: a highly versatile library of synthetic histone H3 and H4 mutants. Cell. 134: 1066-78. PMID 18805098 DOI: 10.1016/J.Cell.2008.07.019  0.525
2007 Huang H, Jedynak BM, Bader JS. Where have all the interactions gone? Estimating the coverage of two-hybrid protein interaction maps. Plos Computational Biology. 3: e214. PMID 18039026 DOI: 10.1371/Journal.Pcbi.0030214  0.548
2007 Stuart LM, Boulais J, Charriere GM, Hennessy EJ, Brunet S, Jutras I, Goyette G, Rondeau C, Letarte S, Huang H, Ye P, Morales F, Kocks C, Bader JS, Desjardins M, et al. A systems biology analysis of the Drosophila phagosome. Nature. 445: 95-101. PMID 17151602 DOI: 10.1038/Nature05380  0.547
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