Raj Suryanarayanan - Publications

Affiliations: 
University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Pharmaceutical Chemistry, Physical Chemistry

160 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Du Y, Li J, Xu W, Cote A, Lay-Fortenbery A, Suryanarayanan R, Su Y. Solid-State NMR Spectroscopy to Probe State and Phase Transitions in Frozen Solutions. Molecular Pharmaceutics. PMID 37947441 DOI: 10.1021/acs.molpharmaceut.3c00764  0.717
2023 Li J, Sonje J, Suryanarayanan R. Role of Poloxamer 188 in Preventing Ice-Surface-Induced Protein Destabilization during Freeze-Thawing. Molecular Pharmaceutics. PMID 37535010 DOI: 10.1021/acs.molpharmaceut.3c00312  0.699
2022 Sonje J, Fleagle Chisholm C, Suryanarayanan R. Frozen Storage of Proteins: Use of Mannitol to Generate a Homogenous Freeze-concentrate. International Journal of Pharmaceutics. 121995. PMID 35809832 DOI: 10.1016/j.ijpharm.2022.121995  0.343
2022 Li J, Duggirala NK, Kumar NSK, Su Y, Suryanarayanan R. Design of Ternary Amorphous Solid Dispersions for Enhanced Dissolution of Drug Combinations. Molecular Pharmaceutics. PMID 35797094 DOI: 10.1021/acs.molpharmaceut.2c00307  0.653
2022 Munjal B, Patel SM, Suryanarayanan R. Role of Arginine Salts in Preventing Freezing-induced Increase in Subvisible Particles in Protein Formulations. International Journal of Pharmaceutics. 121694. PMID 35331829 DOI: 10.1016/j.ijpharm.2022.121694  0.359
2022 Krishna Kumar NS, Suryanarayanan R. Crystallization Propensity of Amorphous Pharmaceuticals: Kinetics and Thermodynamics. Molecular Pharmaceutics. PMID 34979803 DOI: 10.1021/acs.molpharmaceut.1c00839  0.319
2021 Sonje J, Thakral S, Krueger S, Suryanarayanan R. Reversible Self-Association in Lactate Dehydrogenase during Freeze-Thaw in Buffered Solutions Using Neutron Scattering. Molecular Pharmaceutics. PMID 34709831 DOI: 10.1021/acs.molpharmaceut.1c00666  0.309
2021 Duggirala NK, Sonje J, Yuan X, Shalaev E, Suryanarayanan R. Phase behavior of poloxamer 188 in frozen aqueous solutions - Influence of processing conditions and cosolutes. International Journal of Pharmaceutics. 609: 121145. PMID 34600056 DOI: 10.1016/j.ijpharm.2021.121145  0.307
2021 Taylor LS, Bergström CAS, Lavasanifar A, Qian F, Suryanarayanan R, Thurecht KJ. Celebrating Women in the Pharmaceutical Sciences. Molecular Pharmaceutics. PMID 33683129 DOI: 10.1021/acs.molpharmaceut.0c01197  0.303
2020 Kaur N, Young VG, Su Y, Suryanarayanan R. Partial Dehydration of Levothyroxine Sodium Pentahydrate in a Drug Product Environment: Structural Insights into Stability. Molecular Pharmaceutics. PMID 32960611 DOI: 10.1021/acs.molpharmaceut.0c00661  0.351
2020 Thakral S, Sonje J, Suryanarayanan R. Anomalous behavior of mannitol hemihydrate: Implications on sucrose crystallization in colyophilized systems. International Journal of Pharmaceutics. 587: 119629. PMID 32653598 DOI: 10.1016/J.Ijpharm.2020.119629  0.479
2020 Sonje J, Thakral S, Suryanarayanan R. -Butanol Enables Dual Functionality of Mannitol: A Cryoprotectant in Frozen Systems and Bulking Agent in Freeze-Dried Formulations. Molecular Pharmaceutics. PMID 32633520 DOI: 10.1021/Acs.Molpharmaceut.0C00492  0.456
2020 Thorat AA, Munjal B, Geders TW, Suryanarayanan R. Freezing-induced protein aggregation - Role of pH shift and potential mitigation strategies. Journal of Controlled Release : Official Journal of the Controlled Release Society. 323: 591-599. PMID 32335158 DOI: 10.1016/J.Jconrel.2020.04.033  0.41
2020 Koranne S, Lalge R, Suryanarayanan R. Modulation of Microenvironmental Acidity: A Strategy to Mitigate Salt Disproportionation in Drug Product Environment. Molecular Pharmaceutics. PMID 32142293 DOI: 10.1021/Acs.Molpharmaceut.0C00024  0.331
2020 Bhatnagar BS, Sonje J, Shalaev E, Martin SWH, Teagarden DL, Suryanarayanan R. A refined phase diagram of the tert-butanol-water system and implications on lyophilization process optimization of pharmaceuticals. Physical Chemistry Chemical Physics : Pccp. PMID 31894786 DOI: 10.1039/C9Cp06576H  0.444
2019 Sahoo A, Kumar NSK, Suryanarayanan R. Crosslinking: An avenue to develop stable amorphous solid dispersion with high drug loading and tailored physical stability. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 31499085 DOI: 10.1016/J.Jconrel.2019.09.007  0.373
2019 Jena S, Krishna Kumar NS, Aksan A, Suryanarayanan R. Stability of Lyophilized Albumin Formulation: Role of Excipient Crystallinity and Molecular Mobility. International Journal of Pharmaceutics. 118568. PMID 31352055 DOI: 10.1016/J.Ijpharm.2019.118568  0.458
2019 Kaur N, Duggirala NK, Thakral S, Suryanarayanan R. The Role of Lattice Disorder in Water Mediated Dissociation of Pharmaceutical Cocrystal Systems. Molecular Pharmaceutics. PMID 31117742 DOI: 10.1021/Acs.Molpharmaceut.9B00386  0.323
2019 Snell JR, Kumar NSK, Suryanarayanan R, Randolph TW. Nanobubbles in Reconstituted Lyophilized Formulations: Interaction with Proteins and Mechanism of Formation. Journal of Pharmaceutical Sciences. PMID 31095959 DOI: 10.1016/J.Xphs.2019.05.005  0.391
2019 Thorat AA, Suryanarayanan R. Characterization of Phosphate Buffered Saline (PBS) in Frozen State and after Freeze-Drying. Pharmaceutical Research. 36: 98. PMID 31087169 DOI: 10.1007/S11095-019-2619-2  0.432
2019 Duggirala NK, Li J, Kumar NSK, Gopinath T, Suryanarayanan R. A supramolecular synthon approach to design amorphous solid dispersions with exceptional physical stability. Chemical Communications (Cambridge, England). PMID 30972394 DOI: 10.1039/C9Cc02021G  0.68
2019 Koranne S, Krzyzaniak JF, Luthra S, Arora KK, Suryanarayanan R. Role of Coformer and Excipient Properties on the Solid-State Stability of Theophylline Cocrystals Crystal Growth & Design. 19: 868-875. DOI: 10.1021/Acs.Cgd.8B01430  0.346
2018 Fung MH, Suryanarayanan R. Effect of organic acids on molecular mobility, physical stability and dissolution of ternary ketoconazole spray dried dispersions. Molecular Pharmaceutics. PMID 30359037 DOI: 10.1021/Acs.Molpharmaceut.8B00593  0.361
2018 Thakral S, Koranne S, Suryanarayanan R. Intra-Vial Heterogeneity in Physical Form of Mannitol in Colyophilized Binary Systems. Pharmaceutical Research. 35: 214. PMID 30242778 DOI: 10.1007/S11095-018-2499-X  0.376
2018 Kulkarni SS, Suryanarayanan R, Rinella JV, Bogner RH. Mechanisms by Which Crystalline Mannitol Improves the Reconstitution Time of High Concentration Lyophilized Protein Formulations. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 30056143 DOI: 10.1016/J.Ejpb.2018.07.022  0.401
2018 Koranne SA, Sahoo A, Krzyzaniak JF, Luthra S, Arora KK, Suryanarayanan R. Challenges in transitioning cocrystals from bench to bedside: Dissociation in prototype drug product environment. Molecular Pharmaceutics. PMID 29947519 DOI: 10.1021/Acs.Molpharmaceut.8B00340  0.385
2018 Fung MH, Bērziņš K, Suryanarayanan R. Physical stability and dissolution behavior of ketoconazole-organic acid coamorphous systems. Molecular Pharmaceutics. PMID 29528656 DOI: 10.1021/Acs.Molpharmaceut.8B00035  0.399
2018 Fung MH, DeVault M, Kuwata KT, Suryanarayanan R. Drug-excipient interactions: effect on molecular mobility and physical stability of ketoconazole-organic acid coamorphous systems. Molecular Pharmaceutics. PMID 29309158 DOI: 10.1021/Acs.Molpharmaceut.7B00932  0.367
2018 Koranne S, Thakral S, Suryanarayanan R. Effect of Formulation and Process Parameters on the Disproportionation of Indomethacin Sodium in Buffered Lyophilized Formulations. Pharmaceutical Research. 35: 21. PMID 29305664 DOI: 10.1007/S11095-017-2310-4  0.379
2018 Be̅rziņš K, Suryanarayanan R. Compression-Induced Crystallization in Sucrose-Polyvinylpyrrolidone Amorphous Solid Dispersions Crystal Growth & Design. 18: 839-848. DOI: 10.1021/Acs.Cgd.7B01305  0.429
2017 Thakral S, Wolf A, Beilman GJ, Suryanarayanan R. Development and in vivo evaluation of a novel lyophilized formulation for the treatment of hemorrhagic shock. International Journal of Pharmaceutics. 537: 162-171. PMID 29274369 DOI: 10.1016/J.Ijpharm.2017.12.024  0.358
2017 Duggirala NK, Vyas A, Krzyzaniak JF, Arora KK, Suryanarayanan R. Mechanistic Insight into Caffeine-Oxalic Cocrystal Dissociation in Formulations: Role of Excipients. Molecular Pharmaceutics. PMID 28990387 DOI: 10.1021/Acs.Molpharmaceut.7B00587  0.34
2017 Koranne SA, Govindarajan R, Suryanarayanan R. Investigation of Spatial Heterogeneity of Salt Disproportionation in Tablets by Synchrotron X-ray Diffractometry. Molecular Pharmaceutics. PMID 28195490 DOI: 10.1021/Acs.Molpharmaceut.6B01052  0.364
2017 Fung MH, Suryanarayanan R. Use of a Plasticizer for Physical Stability Prediction of Amorphous Solid Dispersions Crystal Growth & Design. 17: 4315-4325. DOI: 10.1021/Acs.Cgd.7B00625  0.47
2017 Mohapatra S, Samanta S, Kothari K, Mistry P, Suryanarayanan R. Effect of Polymer Molecular Weight on the Crystallization Behavior of Indomethacin Amorphous Solid Dispersions Crystal Growth & Design. 17: 3142-3150. DOI: 10.1021/Acs.Cgd.7B00096  0.327
2017 Mistry P, Amponsah-Efah KK, Suryanarayanan R. Rapid Assessment of the Physical Stability of Amorphous Solid Dispersions Crystal Growth & Design. 17: 2478-2485. DOI: 10.1021/Acs.Cgd.6B01901  0.427
2016 Jena S, Horn J, Suryanarayanan R, Friess W, Aksan A. Effects of Excipient Interactions on the State of the Freeze-Concentrate and Protein Stability. Pharmaceutical Research. PMID 27981449 DOI: 10.1007/S11095-016-2078-Y  0.411
2016 Thakral NK, Behme RJ, Aburub A, Peterson JA, Woods TA, Diseroad BA, Suryanarayanan R, Stephenson GA. Salt Disproportionation in the Solid-State: role of solubility and counter-ion volatility. Molecular Pharmaceutics. PMID 27766882 DOI: 10.1021/Acs.Molpharmaceut.6B00745  0.367
2016 Mehta M, Suryanarayanan R. ACCELERATED PHYSICAL STABILITY TESTING OF AMORPHOUS DISPERSIONS. Molecular Pharmaceutics. PMID 27299377 DOI: 10.1021/Acs.Molpharmaceut.6B00218  0.437
2016 Mehta M, McKenna GB, Suryanarayanan R. Molecular mobility in glassy dispersions. The Journal of Chemical Physics. 144: 204506. PMID 27250315 DOI: 10.1063/1.4950768  0.348
2016 Mehta M, Kothari K, Ragoonanan V, Suryanarayanan R. EFFECT OF WATER ON MOLECULAR MOBILITY AND PHYSICAL STABILITY OF AMORPHOUS PHARMACEUTICALS. Molecular Pharmaceutics. PMID 26954586 DOI: 10.1021/Acs.Molpharmaceut.5B00950  0.433
2016 Jena S, Suryanarayanan R, Aksan A. Mutual Influence of Mannitol and Trehalose on Crystallization Behavior in Frozen Solutions. Pharmaceutical Research. PMID 26908047 DOI: 10.1007/S11095-016-1883-7  0.469
2016 Mehta M, Ragoonanan V, McKenna GB, Suryanarayanan R. CORRELATION BETWEEN MOLECULAR MOBILITY AND PHYSICAL STABILITY IN SUPERCOOLED & GLASSY PHARMACEUTICALS. Molecular Pharmaceutics. PMID 26895136 DOI: 10.1021/Acs.Molpharmaceut.5B00853  0.373
2016 Thakral S, Terban MW, Thakral NK, Suryanarayanan R. Recent advances in the characterization of amorphous pharmaceuticals by X-ray diffractometry. Advanced Drug Delivery Reviews. 100: 183-93. PMID 26712710 DOI: 10.1016/J.Addr.2015.12.013  0.413
2016 Mistry P, Suryanarayanan R. Strength of Drug-Polymer Interactions: Implications for Crystallization in Dispersions Crystal Growth and Design. 16: 5141-5149. DOI: 10.1021/Acs.Cgd.6B00714  0.419
2015 Thakral NK, Yamada H, Stephenson GA, Suryanarayanan R. Spatial Distribution of Trehalose Dihydrate Crystallization in Tablets by X-ray Diffractometry. Molecular Pharmaceutics. 12: 3766-75. PMID 26332906 DOI: 10.1021/Acs.Molpharmaceut.5B00567  0.409
2015 Mistry P, Mohapatra S, Gopinath T, Vogt FG, Suryanarayanan R. Role of the Strength of Drug-Polymer Interactions on the Molecular Mobility and Crystallization Inhibition in Ketoconazole Solid Dispersions. Molecular Pharmaceutics. 12: 3339-50. PMID 26070543 DOI: 10.1021/Acs.Molpharmaceut.5B00333  0.401
2015 Thakral S, Suryanarayanan R. Salt formation during freeze-drying--an approach to enhance indomethacin dissolution. Pharmaceutical Research. 32: 3722-31. PMID 26063046 DOI: 10.1007/S11095-015-1732-0  0.375
2015 Kothari K, Ragoonanan V, Suryanarayanan R. The role of polymer concentration on the molecular mobility and physical stability of nifedipine solid dispersions. Molecular Pharmaceutics. 12: 1477-84. PMID 25894099 DOI: 10.1021/Mp500800C  0.347
2015 Arora KK, Bhardwaj SP, Mistry P, Suryanarayanan R. Modulating the dehydration conditions of adefovir dipivoxil dihydrate to obtain different physical forms of anhydrate. Journal of Pharmaceutical Sciences. 104: 1056-64. PMID 25545839 DOI: 10.1002/Jps.24296  0.69
2015 Thakral NK, Mohapatra S, Stephenson GA, Suryanarayanan R. Compression-induced crystallization of amorphous indomethacin in tablets: characterization of spatial heterogeneity by two-dimensional X-ray diffractometry. Molecular Pharmaceutics. 12: 253-63. PMID 25438193 DOI: 10.1021/Mp5005788  0.418
2015 Kothari K, Ragoonanan V, Suryanarayanan R. The role of drug-polymer hydrogen bonding interactions on the molecular mobility and physical stability of nifedipine solid dispersions. Molecular Pharmaceutics. 12: 162-70. PMID 25426538 DOI: 10.1021/Mp5005146  0.305
2015 Govindarajan R, Landis M, Hancock B, Gatlin LA, Suryanarayanan R, Shalaev EY. Surface acidity and solid-state compatibility of excipients with an acid-sensitive API: case study of atorvastatin calcium. Aaps Pharmscitech. 16: 354-63. PMID 25319055 DOI: 10.1208/S12249-014-0231-7  0.346
2014 Bhardwaj SP, Arora KK, Kwong E, Templeton A, Clas SD, Suryanarayanan R. Mechanism of amorphous itraconazole stabilization in polymer solid dispersions: role of molecular mobility. Molecular Pharmaceutics. 11: 4228-37. PMID 25325389 DOI: 10.1021/Mp5004515  0.74
2014 Sundaramurthi P, Suryanarayanan R. Azithromycin hydrates-implications of processing-induced phase transformations. Journal of Pharmaceutical Sciences. 103: 3095-106. PMID 25139082 DOI: 10.1002/Jps.24084  0.788
2014 Kothari K, Ragoonanan V, Suryanarayanan R. Influence of molecular mobility on the physical stability of amorphous pharmaceuticals in the supercooled and glassy States. Molecular Pharmaceutics. 11: 3048-55. PMID 25105216 DOI: 10.1021/Mp500229D  0.4
2014 Bhattacharya S, Bhardwaj SP, Suryanarayanan R. Molecular motions in sucrose-PVP and sucrose-sorbitol dispersions-II. Implications of annealing on secondary relaxations. Pharmaceutical Research. 31: 2822-8. PMID 24792829 DOI: 10.1007/S11095-014-1379-2  0.753
2014 Ragoonanan V, Suryanarayanan R. Ultrasonication as a potential tool to predict solute crystallization in freeze-concentrates. Pharmaceutical Research. 31: 1512-24. PMID 24398694 DOI: 10.1007/S11095-013-1257-3  0.415
2013 Thakral NK, Ragoonanan V, Suryanarayanan R. Quantification, mechanism, and mitigation of active ingredient phase transformation in tablets. Molecular Pharmaceutics. 10: 3128-36. PMID 23869937 DOI: 10.1021/Mp400180N  0.339
2013 Saxena A, Jean YC, Suryanarayanan R. Annealing effect reversal by water sorption-desorption and heating above the glass transition temperature - Comparison of properties Molecular Pharmaceutics. 10: 3005-3012. PMID 23834191 DOI: 10.1021/Mp400099R  0.379
2013 Mehta M, Bhardwaj SP, Suryanarayanan R. Controlling the physical form of mannitol in freeze-dried systems. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 85: 207-13. PMID 23643784 DOI: 10.1016/J.Ejpb.2013.04.010  0.766
2013 Arora KK, Thakral S, Suryanarayanan R. Instability in theophylline and carbamazepine hydrate tablets: cocrystal formation due to release of lattice water. Pharmaceutical Research. 30: 1779-89. PMID 23568521 DOI: 10.1007/S11095-013-1022-7  0.33
2013 Bhardwaj SP, Arora KK, Kwong E, Templeton A, Clas SD, Suryanarayanan R. Correlation between molecular mobility and physical stability of amorphous itraconazole. Molecular Pharmaceutics. 10: 694-700. PMID 23198856 DOI: 10.1021/Mp300487U  0.737
2013 Dempah KE, Barich DH, Kaushal AM, Zong Z, Desai SD, Suryanarayanan R, Kirsch L, Munson EJ. Investigating gabapentin polymorphism using solid-state NMR spectroscopy. Aaps Pharmscitech. 14: 19-28. PMID 23180225 DOI: 10.1208/S12249-012-9879-Z  0.352
2013 Bhardwaj SP, Suryanarayanan R. Molecular mobility as a predictor of the water sorption by annealed amorphous trehalose. Pharmaceutical Research. 30: 714-20. PMID 23104580 DOI: 10.1007/S11095-012-0910-6  0.694
2012 Bhardwaj SP, Suryanarayanan R. Molecular mobility as an effective predictor of the physical stability of amorphous trehalose. Molecular Pharmaceutics. 9: 3209-17. PMID 23003337 DOI: 10.1021/Mp300302G  0.749
2012 Bhardwaj SP, Suryanarayanan R. Use of dielectric spectroscopy to monitor molecular mobility in glassy and supercooled trehalose. The Journal of Physical Chemistry. B. 116: 11728-36. PMID 22913647 DOI: 10.1021/Jp303317P  0.708
2012 Sundaramurthi P, Burcusa MR, Suryanarayanan R. Physical characterization of pentamidine isethionate during freeze-drying-relevance to development of stable lyophilized product. Journal of Pharmaceutical Sciences. 101: 1732-43. PMID 22271285 DOI: 10.1002/Jps.23055  0.821
2012 Chakravarty P, Suryanarayanan R, Govindarajan R. Phase transformation in thiamine hydrochloride tablets: Influence on tablet microstructure, physical properties, and performance. Journal of Pharmaceutical Sciences. 101: 1410-22. PMID 22213350 DOI: 10.1002/Jps.23020  0.614
2012 Sundaramurthi P, Suryanarayanan R. Calorimetry and complementary techniques to characterize frozen and freeze-dried systems. Advanced Drug Delivery Reviews. 64: 384-95. PMID 22210136 DOI: 10.1016/J.Addr.2011.12.004  0.815
2011 Kaushal AM, Vangala VR, Suryanarayanan R. Unusual effect of water vapor pressure on dehydration of dibasic calcium phosphate dihydrate. Journal of Pharmaceutical Sciences. 100: 1456-66. PMID 24081471 DOI: 10.1002/Jps.22372  0.351
2011 Sundaramurthi P, Suryanarayanan R. Predicting the crystallization propensity of carboxylic acid buffers in frozen systems--relevance to freeze-drying. Journal of Pharmaceutical Sciences. 100: 1288-93. PMID 24081466 DOI: 10.1002/Jps.22374  0.819
2011 Zong Z, Desai SD, Kaushal AM, Barich DH, Huang HS, Munson EJ, Suryanarayanan R, Kirsch LE. The stabilizing effect of moisture on the solid-state degradation of gabapentin. Aaps Pharmscitech. 12: 924-31. PMID 21744168 DOI: 10.1208/S12249-011-9652-8  0.383
2011 Bhardwaj SP, Suryanarayanan R. Subtraction of DC conductivity and annealing: approaches to identify Johari-Goldstein relaxation in amorphous trehalose. Molecular Pharmaceutics. 8: 1416-22. PMID 21639143 DOI: 10.1021/Mp2000154  0.7
2011 Sundaramurthi P, Suryanarayanan R. Thermophysical properties of carboxylic and amino acid buffers at subzero temperatures: relevance to frozen state stabilization. The Journal of Physical Chemistry. B. 115: 7154-64. PMID 21561117 DOI: 10.1021/Jp202167P  0.818
2011 Arora KK, Tayade NG, Suryanarayanan R. Unintended water mediated cocrystal formation in carbamazepine and aspirin tablets. Molecular Pharmaceutics. 8: 982-9. PMID 21548636 DOI: 10.1021/Mp200043U  0.41
2011 Bhattacharya S, Suryanarayanan R. Molecular motions in sucrose-PVP and sucrose-sorbitol dispersions: I. Implications of global and local mobility on stability. Pharmaceutical Research. 28: 2191-203. PMID 21499981 DOI: 10.1007/S11095-011-0447-0  0.552
2011 Bhatnagar BS, Martin SW, Hodge TS, Das TK, Joseph L, Teagarden DL, Shalaev EY, Suryanarayanan R. Investigation of PEG crystallization in frozen and freeze-dried PEGylated recombinant human growth hormone-sucrose systems: implications on storage stability. Journal of Pharmaceutical Sciences. 100: 3062-75. PMID 21491456 DOI: 10.1002/Jps.22562  0.481
2011 Sundaramurthi P, Suryanarayanan R. The effect of crystallizing and non-crystallizing cosolutes on succinate buffer crystallization and the consequent pH shift in frozen solutions. Pharmaceutical Research. 28: 374-85. PMID 20927571 DOI: 10.1007/S11095-010-0282-8  0.81
2011 Lohani S, Nesmelova IV, Suryanarayanan R, Grant DJW. Spectroscopic characterization of molecular aggregates in solutions: Impact on crystallization of indomethacin polymorphs from acetonitrile and ethanol Crystal Growth and Design. 11: 2368-2378. DOI: 10.1021/Cg200138B  0.677
2010 Bhatnagar BS, Martin SM, Teagarden DL, Shalaev EY, Suryanarayanan R. Investigation of PEG crystallization in frozen PEG-sucrose-water solutions: II. Characterization of the equilibrium behavior during freeze-thawing. Journal of Pharmaceutical Sciences. 99: 4510-24. PMID 20845450 DOI: 10.1002/Jps.22182  0.379
2010 Sundaramurthi P, Suryanarayanan R. Influence of crystallizing and non-crystallizing cosolutes on trehalose crystallization during freeze-drying. Pharmaceutical Research. 27: 2384-93. PMID 20824310 DOI: 10.1007/S11095-010-0221-8  0.806
2010 Sundaramurthi P, Patapoff TW, Suryanarayanan R. Crystallization of trehalose in frozen solutions and its phase behavior during drying. Pharmaceutical Research. 27: 2374-83. PMID 20811935 DOI: 10.1007/S11095-010-0243-2  0.815
2010 Chakravarty P, Govindarajan R, Suryanarayanan R. Investigation of solution and vapor phase mediated phase transformation in thiamine hydrochloride. Journal of Pharmaceutical Sciences. 99: 3941-52. PMID 20575002 DOI: 10.1002/Jps.22240  0.596
2010 Chen D, Haugstad G, Li ZJ, Suryanarayanan R. Water sorption induced transformations in crystalline solid surfaces: characterization by atomic force microscopy. Journal of Pharmaceutical Sciences. 99: 4032-41. PMID 20574999 DOI: 10.1002/Jps.22258  0.555
2010 Sundaramurthi P, Shalaev E, Suryanarayanan R. Calorimetric and diffractometric evidence for the sequential crystallization of buffer components and the consequential pH swing in frozen solutions. The Journal of Physical Chemistry. B. 114: 4915-23. PMID 20302316 DOI: 10.1021/Jp100531V  0.805
2010 Chakravarty P, Berendt RT, Munson EJ, Young VG, Govindarajan R, Suryanarayanan R. Insights into the dehydration behavior of thiamine hydrochloride (vitamin B1) hydrates: part II. Journal of Pharmaceutical Sciences. 99: 1882-95. PMID 19824063 DOI: 10.1002/Jps.21968  0.604
2010 Chakravarty P, Berendt RT, Munson EJ, Young VG, Govindarajan R, Suryanarayanan R. Insights into the dehydration behavior of thiamine hydrochloride (vitamin B1) hydrates: part I. Journal of Pharmaceutical Sciences. 99: 816-27. PMID 19623540 DOI: 10.1002/jps.21876  0.586
2010 Sundaramurthi P, Suryanarayanan R. Trehalose crystallization during freeze-drying: Implications on lyoprotection Journal of Physical Chemistry Letters. 1: 510-514. DOI: 10.1021/Jz900338M  0.827
2010 Sundaramurthi P, Shalaev E, Suryanarayanan R. "pH swing" in frozen solutions - Consequence of sequential crystallization of buffer components Journal of Physical Chemistry Letters. 1: 265-268. DOI: 10.1021/Jz900164Q  0.798
2010 Chakravarty P, Suryanarayanan R. Characterization and structure analysis of thiamine hydrochloride methanol solvate Crystal Growth and Design. 10: 4414-4420. DOI: 10.1021/Cg100522F  0.627
2009 Chakravarty P, Bhardwaj SP, King L, Suryanarayanan R. Monitoring phase transformations in intact tablets of trehalose by FT-Raman spectroscopy. Aaps Pharmscitech. 10: 1420-6. PMID 19937407 DOI: 10.1208/S12249-009-9337-8  0.755
2009 Lu E, Ewing S, Gatlin L, Suryanarayanan R, Shalaev E. The effect of bulking agents on the chemical stability of acid-sensitive compounds in freeze-dried formulations: sucrose inversion study. Journal of Pharmaceutical Sciences. 98: 3387-96. PMID 19544366 DOI: 10.1002/Jps.21727  0.581
2009 Bhattacharya S, Suryanarayanan R. Local mobility in amorphous pharmaceuticals--characterization and implications on stability. Journal of Pharmaceutical Sciences. 98: 2935-53. PMID 19499564 DOI: 10.1002/Jps.21728  0.559
2009 Varshney DB, Elliott JA, Gatlin LA, Kumar S, Suryanarayanan R, Shalaev EY. Synchrotron X-ray diffraction investigation of the anomalous behavior of ice during freezing of aqueous systems. The Journal of Physical Chemistry. B. 113: 6177-82. PMID 19358549 DOI: 10.1021/Jp900404M  0.323
2009 Varshney DB, Sundaramurthi P, Kumar S, Shalaev EY, Kang SW, Gatlin LA, Suryanarayanan R. Phase transitions in frozen systems and during freeze-drying: quantification using synchrotron X-ray diffractometry. Pharmaceutical Research. 26: 1596-606. PMID 19326191 DOI: 10.1007/S11095-009-9868-4  0.813
2009 Dranca I, Bhattacharya S, Vyazovkin S, Suryanarayanan R. Implications of global and local mobility in amorphous sucrose and trehalose as determined by differential scanning calorimetry. Pharmaceutical Research. 26: 1064-72. PMID 19130185 DOI: 10.1007/S11095-008-9817-7  0.534
2009 Miyazaki T, Sivaprakasam K, Tantry J, Suryanarayanan R. Physical characterization of dibasic calcium phosphate dihydrate and anhydrate. Journal of Pharmaceutical Sciences. 98: 905-16. PMID 18563795 DOI: 10.1002/Jps.21443  0.378
2008 Chatterjee K, Shalaev EY, Suryanarayanan R, Govindarajan R. Correlation between chemical reactivity and the Hammett acidity function in amorphous solids using inversion of sucrose as a model reaction. Journal of Pharmaceutical Sciences. 97: 274-86. PMID 17828730 DOI: 10.1002/Jps.21081  0.643
2008 Lu E, Rodríguez-Hornedo N, Suryanarayanan R. A rapid thermal method for cocrystal screening Crystengcomm. 10: 665-668. DOI: 10.1039/B801713C  0.527
2007 Yamada H, Suryanarayanan R. X-ray powder diffractometry of intact film coated tablets--an approach to monitor the physical form of the active pharmaceutical ingredient during processing and storage. Journal of Pharmaceutical Sciences. 96: 2029-36. PMID 17541977 DOI: 10.1002/Jps.20811  0.317
2007 Tantry JS, Tank J, Suryanarayanan R. Processing-induced phase transitions of theophylline--implications on the dissolution of theophylline tablets. Journal of Pharmaceutical Sciences. 96: 1434-44. PMID 17455350 DOI: 10.1002/Jps.20746  0.391
2007 Varshney DB, Kumar S, Shalaev EY, Sundaramurthi P, Kang SW, Gatlin LA, Suryanarayanan R. Glycine crystallization in frozen and freeze-dried systems: effect of pH and buffer concentration. Pharmaceutical Research. 24: 593-604. PMID 17245648 DOI: 10.1007/S11095-006-9178-Z  0.814
2006 Nunes C, Mahendrasingam A, Suryanarayanan R. Investigation of the multi-step dehydration reaction of theophylline monohydrate using 2-dimensional powder X-ray diffractometry. Pharmaceutical Research. 23: 2393-404. PMID 16947081 DOI: 10.1007/S11095-006-9022-5  0.644
2006 Varshney DB, Kumar S, Shalaev EY, Kang SW, Gatlin LA, Suryanarayanan R. Solute crystallization in frozen systems-use of synchrotron radiation to improve sensitivity. Pharmaceutical Research. 23: 2368-74. PMID 16927181 DOI: 10.1007/S11095-006-9051-0  0.458
2006 Rani M, Govindarajan R, Surana R, Suryanarayanan R. Structure in dehydrated trehalose dihydrate--evaluation of the concept of partial crystallinity. Pharmaceutical Research. 23: 2356-67. PMID 16927180 DOI: 10.1007/S11095-006-9058-6  0.585
2006 Govindarajan R, Chatterjee K, Gatlin L, Suryanarayanan R, Shalaev EY. Impact of freeze-drying on ionization of sulfonephthalein probe molecules in trehalose-citrate systems. Journal of Pharmaceutical Sciences. 95: 1498-510. PMID 16721795 DOI: 10.1002/Jps.20620  0.624
2005 Nunes C, Mahendrasingam A, Suryanarayanan R. Quantification of crystallinity in substantially amorphous materials by synchrotron X-ray powder diffractometry. Pharmaceutical Research. 22: 1942-53. PMID 16132342 DOI: 10.1007/S11095-005-7626-9  0.653
2005 Chatterjee K, Shalaev EY, Suryanarayanan R. Raffinose crystallization during freeze-drying and its impact on recovery of protein activity. Pharmaceutical Research. 22: 303-9. PMID 15783079 DOI: 10.1007/S11095-004-1198-Y  0.673
2005 Telang C, Suryanarayanan R. Crystallization of cephalothin sodium during lyophilization from tert-butyl alcohol-water cosolvent system. Pharmaceutical Research. 22: 153-60. PMID 15771242 DOI: 10.1007/S11095-004-9021-3  0.813
2005 Chatterjee K, Shalaev EY, Suryanarayanan R. Partially crystalline systems in lyophilization: I. Use of ternary state diagrams to determine extent of crystallization of bulking agent. Journal of Pharmaceutical Sciences. 94: 798-808. PMID 15729706 DOI: 10.1002/Jps.20303  0.718
2005 Chatterjee K, Shalaev EY, Suryanarayanan R. Partially crystalline systems in lyophilization: II. Withstanding collapse at high primary drying temperatures and impact on protein activity recovery. Journal of Pharmaceutical Sciences. 94: 809-20. PMID 15729705 DOI: 10.1002/Jps.20304  0.633
2005 Surana R, Pyne A, Rani M, Suryanarayanan R. Measurement of enthalpic relaxation by differential scanning calorimetry - Effect of experimental conditions Thermochimica Acta. 433: 173-182. DOI: 10.1016/J.Tca.2005.02.014  0.754
2004 Nunes C, Suryanarayanan R, Botez CE, Stephens PW. Characterization and crystal structure of D-mannitol hemihydrate. Journal of Pharmaceutical Sciences. 93: 2800-9. PMID 15368529 DOI: 10.1002/Jps.20185  0.696
2004 Bai SJ, Rani M, Suryanarayanan R, Carpenter JF, Nayar R, Manning MC. Quantification of glycine crystallinity by near-infrared (NIR) spectroscopy. Journal of Pharmaceutical Sciences. 93: 2439-47. PMID 15349954 DOI: 10.1002/Jps.20153  0.344
2004 Surana R, Pyne A, Suryanarayanan R. Effect of preparation method on physical properties of amorphous trehalose. Pharmaceutical Research. 21: 1167-76. PMID 15290856 DOI: 10.1023/B:Pham.0000033003.17251.C3  0.736
2004 Debnath S, Suryanarayanan R. Influence of processing-induced phase transformations on the dissolution of theophylline tablets. Aaps Pharmscitech. 5: E8. PMID 15198529 DOI: 10.1208/Pt050108  0.587
2004 Surana R, Pyne A, Suryanarayanan R. Effect of aging on the physical properties of amorphous trehalose. Pharmaceutical Research. 21: 867-74. PMID 15180347 DOI: 10.1023/B:Pham.0000026441.77567.75  0.766
2004 Debnath S, Predecki P, Suryanarayanan R. Use of glancing angle X-ray powder diffractometry to depth-profile phase transformations during dissolution of indomethacin and theophylline tablets. Pharmaceutical Research. 21: 149-59. PMID 14984270 DOI: 10.1023/B:Pham.0000012163.89163.F8  0.609
2004 Nunes C, Han J, Monkhouse DC, Suryanarayanan R. Preformulation studies to meet the challenges in the manufacture of betaine solid dosage form. Journal of Pharmaceutical Sciences. 93: 38-47. PMID 14648634 DOI: 10.1002/Jps.10508  0.639
2003 Surana R, Pyne A, Suryanarayanan R. Solid-vapor interactions: influence of environmental conditions on the dehydration of carbamazepine dihydrate. Aaps Pharmscitech. 4: E68. PMID 15198563 DOI: 10.1208/Pt040468  0.758
2003 Telang C, Suryanarayanan R, Yu L. Crystallization of D-mannitol in binary mixtures with NaCl: phase diagram and polymorphism. Pharmaceutical Research. 20: 1939-45. PMID 14725357 DOI: 10.1023/B:Pham.0000008040.14958.Bc  0.808
2003 Surana R, Randall L, Pyne A, Vemuri NM, Suryanarayanan R. Determination of glass transition temperature and in situ study of the plasticizing effect of water by inverse gas chromatography. Pharmaceutical Research. 20: 1647-54. PMID 14620521 DOI: 10.1023/A:1026199604374  0.758
2003 Pyne A, Chatterjee K, Suryanarayanan R. Solute crystallization in mannitol-glycine systems--implications on protein stabilization in freeze-dried formulations. Journal of Pharmaceutical Sciences. 92: 2272-83. PMID 14603512 DOI: 10.1002/Jps.10487  0.806
2003 Zhang GG, Paspal SY, Suryanarayanan R, Grant DJ. Racemic species of sodium ibuprofen: characterization and polymorphic relationships. Journal of Pharmaceutical Sciences. 92: 1356-66. PMID 12820140 DOI: 10.1002/Jps.10393  0.625
2003 Pyne A, Chatterjee K, Suryanarayanan R. Crystalline to amorphous transition of disodium hydrogen phosphate during primary drying. Pharmaceutical Research. 20: 802-3. PMID 12751637 DOI: 10.1023/A:1023445905372  0.751
2003 Telang C, Yu L, Suryanarayanan R. Effective inhibition of mannitol crystallization in frozen solutions by sodium chloride. Pharmaceutical Research. 20: 660-7. PMID 12739776 DOI: 10.1023/A:1023263203188  0.815
2003 Pyne A, Suryanarayanan R. The effect of additives on the crystallization of cefazolin sodium during freeze-drying. Pharmaceutical Research. 20: 283-91. PMID 12636169 DOI: 10.1023/A:1022239608095  0.725
2003 Botez CE, Stephens PW, Nunes C, Suryanarayanan R. Crystal structure of anhydrous δ-D-mannitol Powder Diffraction. 18: 214-218. DOI: 10.1154/1.1582460  0.662
2003 Pyne A, Surana R, Suryanarayanan R. Enthalpic relaxation in frozen aqueous trehalose solutions Thermochimica Acta. 405: 225-234. DOI: 10.1016/S0040-6031(03)00193-X  0.78
2002 Rastogi SK, Zakrzewski M, Suryanarayanan R. Investigation of solid-state reactions using variable temperature X-ray powder diffractometry. II. Aminophylline monohydrate. Pharmaceutical Research. 19: 1265-73. PMID 12403061 DOI: 10.1023/A:1020386321876  0.585
2002 Pyne A, Surana R, Suryanarayanan R. Crystallization of mannitol below Tg' during freeze-drying in binary and ternary aqueous systems. Pharmaceutical Research. 19: 901-8. PMID 12134964 DOI: 10.1023/A:1016129521485  0.81
2002 Cavatur RK, Vemuri NM, Pyne A, Chrzan Z, Toledo-Velasquez D, Suryanarayanan R. Crystallization behavior of mannitol in frozen aqueous solutions. Pharmaceutical Research. 19: 894-900. PMID 12134963 DOI: 10.1023/A:1016177404647  0.727
2002 Dash AK, Khin-Khin A, Suryanarayanan R. X-ray powder diffractometric method for quantitation of crystalline drug in microparticulate systems. I. Microspheres. Journal of Pharmaceutical Sciences. 91: 983-90. PMID 11948537 DOI: 10.1002/Jps.10090  0.353
2001 Pyne A, Suryanarayanan R. Phase transitions of glycine in frozen aqueous solutions and during freeze-drying. Pharmaceutical Research. 18: 1448-54. PMID 11697471 DOI: 10.1023/A:1012209007411  0.706
2001 Rastogi S, Zakrzewski M, Suryanarayanan R. Investigation of solid-state reactions using variable temperature X-ray powder diffractrometry. I. Aspartame hemihydrate. Pharmaceutical Research. 18: 267-73. PMID 11442263 DOI: 10.1023/A:1011086409967  0.575
2001 Iyengar SS, Phadnis NV, Suryanarayanan R. Quantitative analyses of complex pharmaceutical mixtures by the Rietveld method Powder Diffraction. 16: 20-24. DOI: 10.1154/1.1332076  0.321
2000 Li Y, Han J, Zhang GG, Grant DJ, Suryanarayanan R. In situ dehydration of carbamazepine dihydrate: a novel technique to prepare amorphous anhydrous carbamazepine. Pharmaceutical Development and Technology. 5: 257-66. PMID 10810755 DOI: 10.1081/Pdt-100100540  0.697
2000 Rastogi S, Zamansky I, Roy S, Tyle P, Suryanarayanan R. Solid-state phase transitions of AG337, an antitumor agent. Pharmaceutical Development and Technology. 4: 623-32. PMID 10578517 DOI: 10.1081/Pdt-100101401  0.611
2000 Surana R, Suryanarayanan R. Quantitation of crystallinity in substantially amorphous pharmaceuticals and study of crystallization kinetics by X-ray powder diffractometry Powder Diffraction. 15: 2-6. DOI: 10.1017/S0885715600010757  0.697
1999 Han J, Suryanarayanan R. Influence of environmental conditions on the kinetics and mechanism of dehydration of carbamazepine dihydrate. Pharmaceutical Development and Technology. 3: 587-96. PMID 9834963 DOI: 10.3109/10837459809028643  0.404
1999 Cavatur RK, Suryanarayanan R. Characterization of phase transitions during freeze-drying by in situ X-ray powder diffractometry. Pharmaceutical Development and Technology. 3: 579-86. PMID 9834962 DOI: 10.3109/10837459809028642  0.487
1999 Han J, Suryanarayanan R. A method for the rapid evaluation of the physical stability of pharmaceutical hydrates Thermochimica Acta. 329: 163-170. DOI: 10.1016/S0040-6031(99)00054-4  0.327
1998 Cavatur RK, Suryanarayanan R. Characterization of frozen aqueous solutions by low temperature X-ray powder diffractometry. Pharmaceutical Research. 15: 194-9. PMID 9523303 DOI: 10.1023/A:1011950131312  0.403
1998 Han J, Gupte S, Suryanarayanan R. Applications of pressure differential scanning calorimetry in the study of pharmaceutical hydrates. II. Ampicillin trihydrate International Journal of Pharmaceutics. 170: 63-72. DOI: 10.1016/S0378-5173(98)00123-9  0.37
1997 Han J, Suryanarayanan R. Applications of pressure differential scanning calorimetry in the study of pharmaceutical hydrates. I. Carbamazepine dihydrate. International Journal of Pharmaceutics. 157: 209-218. PMID 10477818 DOI: 10.1016/S0378-5173(97)00231-7  0.316
1997 Phadnis NV, Suryanarayanan R. Polymorphism in anhydrous theophylline--implications on the dissolution rate of theophylline tablets. Journal of Pharmaceutical Sciences. 86: 1256-63. PMID 9383736 DOI: 10.1021/Js9701418  0.412
1997 Phadnis NV, Suryanarayanan R. Simultaneous quantification of an enantiomer and the racemic compound of ibuprofen by X-ray powder diffractometry. Pharmaceutical Research. 14: 1176-80. PMID 9327444 DOI: 10.1023/A:1012198605891  0.304
1997 Phadnis NV, Cavatur RK, Suryanarayanan R. Identification of drugs in pharmaceutical dosage forms by X-ray powder diffractometry. Journal of Pharmaceutical and Biomedical Analysis. 15: 929-43. PMID 9160259 DOI: 10.1016/S0731-7085(96)01939-5  0.314
1997 Duddu SP, Khin-Khin A, Grant DJ, Suryanarayanan R. A novel X-ray powder diffractometric method for studying the reaction between pseudoephedrine enantiomers. Journal of Pharmaceutical Sciences. 86: 340-5. PMID 9050803 DOI: 10.1021/Js960289B  0.64
1992 Suryanarayanan R, Venkatesh S, Hodgin L, Hanson P. Determination of the physical state of salicylic acid in hydrogel formulations by X-ray diffractometry International Journal of Pharmaceutics. 78: 77-83. DOI: 10.1016/0378-5173(92)90357-8  0.35
1991 Young WW, Suryanarayanan R. Kinetics of transition of anhydrous carbamazepine to carbamazepine dihydrate in aqueous suspensions. Journal of Pharmaceutical Sciences. 80: 496-500. PMID 1880732 DOI: 10.1002/Jps.2600800519  0.347
1991 Dash AK, Suryanarayanan R. A liquid-chromatographic method for the determination of tobramycin Journal of Pharmaceutical and Biomedical Analysis. 9: 237-245. PMID 1873319 DOI: 10.1016/0731-7085(91)80152-Y  0.328
1991 Dash AK, Suryanarayanan R. Solid-State Properties of Tobramycin Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 8: 1159-1165. PMID 1788162 DOI: 10.1023/A:1015858503031  0.367
1991 Suryanarayanan R, Herman C. Quantitative analysis of the active ingredient in a multi-component tablet formulation by powder X-ray diffractometry International Journal of Pharmaceutics. 77: 287-295. DOI: 10.1016/0378-5173(91)90329-M  0.313
1990 Suryanarayanan R. Determination of the relative amounts of anhydrous carbamazepine (C15H12N2O) and carbamazepine dihydrate (C15H12N2O.2H2O) in a mixture by powder x-ray diffractometry. Pharmaceutical Research. 6: 1017-24. PMID 2622857 DOI: 10.1023/A:1015970218980  0.309
1990 Suryanarayanan R. Determination of the Relative Amounts of α-carbamazepine and β-carbamazepine in a Mixture by Powder X-Ray Diffractometry Powder Diffraction. 5: 155-159. DOI: 10.1017/S0885715600015608  0.315
1986 Suryanarayanan R, Mitchell A. Phase transitions of calcium gluceptate International Journal of Pharmaceutics. 32: 213-221. DOI: 10.1016/0378-5173(86)90181-X  0.447
1985 Suryanarayanan R, Mitchell A. Evaluation of two concepts of crystallinity using calcium gluceptate as a model compound International Journal of Pharmaceutics. 24: 1-17. DOI: 10.1016/0378-5173(85)90140-1  0.416
1984 Suryanarayanan R, Mitchell AG. Precipitation of calcium gluceptate from aqueous solutions. Journal of Pharmaceutical Sciences. 73: 78-82. PMID 6694089 DOI: 10.1002/Jps.2600730121  0.353
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