Bernd Meibohm - Publications

Affiliations: 
Pharmaceutical Sciences University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Pharmacology, Pharmaceutical Chemistry

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Temrikar ZH, Suryawanshi S, Meibohm B. Pharmacokinetics and Clinical Pharmacology of Monoclonal Antibodies in Pediatric Patients. Paediatric Drugs. PMID 32052309 DOI: 10.1007/S40272-020-00382-7  0.331
2020 Fuhr LM, Hanke N, Meibohm B, Lehr T. Effective Removal of Dabigatran by Idarucizumab or Hemodialysis: A Physiologically Based Pharmacokinetic Modeling Analysis. Clinical Pharmacokinetics. PMID 32020532 DOI: 10.1007/S40262-019-00857-Y  0.302
2019 Shakhnovich V, Meibohm B, Rosenberg A, Kierzek AM, Hasenkamp R, Funk RS, Thalhauser CJ, van der Graaf PH, Wang YC, Hamuro L. Immunogenicity in Clinical Practice and Drug Development: When is it Significant? Clinical and Translational Science. PMID 31762152 DOI: 10.1111/Cts.12717  0.314
2019 Nagesh PKB, Chowdhury P, Hatami E, Kumari S, Kashyap VK, Tripathi MK, Wagh S, Meibohm B, Chauhan SC, Jaggi M, Yallapu MM. Cross linked polyphenol-based drug nano-self assemblies engineered to blockade prostate cancer senescence. Acs Applied Materials & Interfaces. PMID 31553876 DOI: 10.1021/Acsami.9B14738  0.306
2019 Walz A, Lukka PB, Pearce C, Creissen E, Braunstein M, Hickey AJ, Meibohm B, Gonzalez-Juarrero M. Sterilization of Mycobacterium tuberculosis infected samples using methanol preserves anti-tuberculosis drugs for subsequent pharmacological testing studies. Tuberculosis (Edinburgh, Scotland). 117: 52-55. PMID 31378268 DOI: 10.1016/J.Tube.2019.06.002  0.33
2019 Stewart IE, Lukka PB, Liu J, Meibohm B, Gonzalez-Juarrero M, Braunstein MS, Lee RE, Hickey AJ. Development and Characterization of a Dry Powder Formulation for Anti-Tuberculosis Drug Spectinamide 1599. Pharmaceutical Research. 36: 136. PMID 31321552 DOI: 10.1007/S11095-019-2666-8  0.33
2019 Donnenberg VS, Chaikin P, Mandic M, Meibohm B, van den Anker J, Rhinehart E, Nafziger AN, Burris JF. Core Entrustable Professional Activities in Clinical Pharmacology for Entering Residency: Common Problem Drugs and How to Prescribe Them. Journal of Clinical Pharmacology. PMID 30768795 DOI: 10.1002/Jcph.1389  0.321
2019 Rathi C, Lukka PB, Wagh S, Lee RE, Lenaerts AJ, Braunstein M, Hickey A, Gonzalez-Juarrero M, Meibohm B. Comparative pharmacokinetics of spectinamide 1599 after subcutaneous and intrapulmonary aerosol administration in mice. Tuberculosis (Edinburgh, Scotland). 114: 119-122. PMID 30711150 DOI: 10.1016/J.Tube.2018.12.006  0.346
2018 Vaddady PK, Trivedi A, Rathi C, Madhura DB, Liu J, Lee RE, Meibohm B. Dynamic time-kill curve characterization of spectinamide antibiotics 1445 and 1599 for the treatment of tuberculosis. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 30419293 DOI: 10.1016/J.Ejps.2018.11.006  0.365
2018 Santos K, Lukka PB, Grzegorzewicz A, Jackson M, Trivedi A, Pavan F, Chorilli M, Braunstein M, Hickey A, Meibohm B, Gonzalez-Juarrero M. Primary Lung Dendritic Cell Cultures to Assess Efficacy of Spectinamide-1599 Against Intracellular . Frontiers in Microbiology. 9: 1895. PMID 30186246 DOI: 10.3389/Fmicb.2018.01895  0.335
2017 He H, Ma D, Crone LB, Butawan M, Meibohm B, Bloomer RJ, Yates CR. Assessment of the Drug-Drug Interaction Potential Between Theacrine and Caffeine in Humans. Journal of Caffeine Research. 7: 95-102. PMID 28875060 DOI: 10.1089/Jcr.2017.0006  0.337
2017 Siricilla S, Mitachi K, Yang J, Eslamimehr S, Lemieux MR, Meibohm B, Ji Y, Kurosu M. A New Combination of a Pleuromutilin Derivative and Doxycycline for Treatment of Multidrug-Resistant Acinetobacter baumannii. Journal of Medicinal Chemistry. PMID 28291943 DOI: 10.1021/Acs.Jmedchem.6B01805  0.346
2017 Liu J, Bruhn DF, Lee RB, Zheng Z, Janusic T, Scherbakov D, Scherman MS, Boshoff HI, Das S, Rakesh, Waidyarachchi SL, Brewer TA, Gracia B, Yang L, Bollinger J, ... ... Meibohm B, et al. Structure-Activity Relationships of Spectinamide Antituberculosis Agents: A Dissection of Ribosomal Inhibition and Native Efflux Avoidance Contributions. Acs Infectious Diseases. 3: 72-88. PMID 28081607 DOI: 10.1021/Acsinfecdis.6B00158  0.35
2017 Herskovitz J, Ryman J, Thway T, Lee S, Zhou L, Chirmule N, Meibohm B, Jawa V. Immune Suppression During Preclinical Drug Development Mitigates Immunogenicity-Mediated Impact on Therapeutic Exposure. The Aaps Journal. PMID 28070711 DOI: 10.1208/S12248-016-0026-8  0.354
2016 Rathi C, Lee RE, Meibohm B. Translational PK/PD of anti-infective therapeutics. Drug Discovery Today. Technologies. 21: 41-49. PMID 27978987 DOI: 10.1016/J.Ddtec.2016.08.004  0.341
2016 Mould DR, Meibohm B. Drug Development of Therapeutic Monoclonal Antibodies. Biodrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. PMID 27342605 DOI: 10.1007/S40259-016-0181-6  0.351
2016 Leeder JS, Meibohm B. Challenges and Opportunities for Increasing the Knowledge Base Related to Drug Biotransformation and Pharmacokinetics during Growth and Development. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 44: 916-23. PMID 27302933 DOI: 10.1124/Dmd.116.071159  0.355
2016 Madhura DB, Trivedi A, Liu J, Boyd VA, Jeffries C, Loveless V, Lee RE, Meibohm B. Tissue Penetration of a Novel Spectinamide Antibiotic for the Treatment of Tuberculosis. The Aaps Journal. PMID 26984832 DOI: 10.1208/S12248-016-9900-7  0.332
2015 Gunn GR, Sealey DC, Jamali F, Meibohm B, Ghosh S, Shankar G. From the Bench to Clinical Practice: Understanding the Challenges and Uncertainties in Immunogenicity Testing for Biopharmaceuticals. Clinical and Experimental Immunology. PMID 26597698 DOI: 10.1111/Cei.12742  0.355
2015 Bruhn DF, Scherman MS, Liu J, Scherbakov D, Meibohm B, Böttger EC, Lenaerts AJ, Lee RE. In vitro and in vivo Evaluation of Synergism between Anti-Tubercular Spectinamides and Non-Classical Tuberculosis Antibiotics. Scientific Reports. 5: 13985. PMID 26365087 DOI: 10.1038/Srep13985  0.38
2015 Bruhn DF, Waidyarachchi SL, Madhura DB, Shcherbakov D, Zheng Z, Liu J, Abdelrahman YM, Singh AP, Duscha S, Rathi C, Lee RB, Belland RJ, Meibohm B, Rosch JW, Böttger EC, et al. Aminomethyl spectinomycins as therapeutics for drug-resistant respiratory tract and sexually transmitted bacterial infections. Science Translational Medicine. 7: 288ra75. PMID 25995221 DOI: 10.1126/Scitranslmed.3010572  0.351
2015 Zhang Y, Wei X, Bajaj G, Barrett JS, Meibohm B, Joshi A, Gupta M. Challenges and considerations for development of therapeutic proteins in pediatric patients. Journal of Clinical Pharmacology. 55: S103-15. PMID 25707958 DOI: 10.1002/Jcph.382  0.354
2014 Feagan BG, Choquette D, Ghosh S, Gladman DD, Ho V, Meibohm B, Zou G, Xu Z, Shankar G, Sealey DC, Russell AS. The challenge of indication extrapolation for infliximab biosimilars. Biologicals : Journal of the International Association of Biological Standardization. 42: 177-83. PMID 24962198 DOI: 10.1016/J.Biologicals.2014.05.005  0.309
2014 Rakesh, Bruhn DF, Scherman MS, Woolhiser LK, Madhura DB, Maddox MM, Singh AP, Lee RB, Hurdle JG, McNeil MR, Lenaerts AJ, Meibohm B, Lee RE. Pentacyclic nitrofurans with in vivo efficacy and activity against nonreplicating Mycobacterium tuberculosis. Plos One. 9: e87909. PMID 24505329 DOI: 10.1371/Journal.Pone.0087909  0.315
2014 Lee RE, Hurdle JG, Liu J, Bruhn DF, Matt T, Scherman MS, Vaddady PK, Zheng Z, Qi J, Akbergenov R, Das S, Madhura DB, Rathi C, Trivedi A, Villellas C, ... ... Meibohm B, et al. Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux. Nature Medicine. 20: 152-8. PMID 24464186 DOI: 10.1038/Nm.3458  0.364
2013 Ramusovic S, Läer S, Meibohm B, Lagler FB, Paul T. Pharmacokinetics of intravenous amiodarone in children. Archives of Disease in Childhood. 98: 989-93. PMID 24051016 DOI: 10.1136/Archdischild-2013-304483  0.324
2013 Trivedi A, Lee RE, Meibohm B. Applications of pharmacometrics in the clinical development and pharmacotherapy of anti-infectives. Expert Review of Clinical Pharmacology. 6: 159-70. PMID 23473593 DOI: 10.1586/Ecp.13.6  0.312
2013 Bai JP, Barrett JS, Burckart GJ, Meibohm B, Sachs HC, Yao L. Strategic biomarkers for drug development in treating rare diseases and diseases in neonates and infants. The Aaps Journal. 15: 447-54. PMID 23334978 DOI: 10.1208/S12248-013-9452-Z  0.31
2013 Thudium K, Bilic S, Leipold D, Mallet W, Kaur S, Meibohm B, Erickson H, Tibbitts J, Zhao H, Gupta M. American Association of Pharmaceutical Scientists National Biotechnology Conference Short Course: Translational Challenges in Developing Antibody-Drug Conjugates: May 24, 2012, San Diego, CA. Mabs. 5: 5-12. PMID 23255090 DOI: 10.4161/Mabs.22909  0.338
2012 Rakesh, Bruhn D, Madhura DB, Maddox M, Lee RB, Trivedi A, Yang L, Scherman MS, Gilliland JC, Gruppo V, McNeil MR, Lenaerts AJ, Meibohm B, Lee RE. Antitubercular nitrofuran isoxazolines with improved pharmacokinetic properties. Bioorganic & Medicinal Chemistry. 20: 6063-72. PMID 22995771 DOI: 10.1016/J.Bmc.2012.08.023  0.331
2012 Barrett JS, Della Casa Alberighi O, Läer S, Meibohm B. Physiologically Based Pharmacokinetic (PBPK) modeling in children Clinical Pharmacology and Therapeutics. 92: 40-49. PMID 22669290 DOI: 10.1038/Clpt.2012.64  0.347
2012 Chirmule N, Jawa V, Meibohm B. Immunogenicity to therapeutic proteins: impact on PK/PD and efficacy. The Aaps Journal. 14: 296-302. PMID 22407289 DOI: 10.1208/S12248-012-9340-Y  0.352
2011 Meibohm B. Population pharmacokinetic/pharmacodynamic analyses as the basis for dosing of therapeutic monoclonal antibodies. Clinical Pharmacokinetics. 50: 823-4. PMID 22087868 DOI: 10.2165/11597950-000000000-00000  0.31
2011 Budha NR, Kovar A, Meibohm B. Comparative performance of cell life span and cell transit models for describing erythropoietic drug effects. The Aaps Journal. 13: 650-61. PMID 22005901 DOI: 10.1208/S12248-011-9302-9  0.672
2011 Prado ME, Ryman JT, Boileau MJ, Martin-Jimenez T, Meibohm B. Pharmacokinetics of ponazuril after oral administration to healthy llamas (Lama glama). American Journal of Veterinary Research. 72: 1386-9. PMID 21962282 DOI: 10.2460/Ajvr.72.10.1386  0.307
2011 Vaddady PK, Mehrotra N, Zhang X, Yates CR, Moore BM, Meibohm B. Pharmacokinetics of a combination of Δ9-tetrahydro-cannabinol and celecoxib in a porcine model of hemorrhagic shock. Biopharmaceutics & Drug Disposition. 32: 89-98. PMID 21341278 DOI: 10.1002/Bdd.740  0.304
2010 Suryawanshi S, Zhang L, Pfister M, Meibohm B. The current role of model-based drug development. Expert Opinion On Drug Discovery. 5: 311-21. PMID 22823084 DOI: 10.1517/17460441003713470  0.334
2010 Vaddady PK, Lee RE, Meibohm B. In vitro pharmacokinetic/pharmacodynamic models in anti-infective drug development: focus on TB. Future Medicinal Chemistry. 2: 1355-69. PMID 21359155 DOI: 10.4155/Fmc.10.224  0.404
2010 Chen J, Wang Z, Li CM, Lu Y, Vaddady PK, Meibohm B, Dalton JT, Miller DD, Li W. Discovery of novel 2-aryl-4-benzoyl-imidazoles targeting the colchicines binding site in tubulin as potential anticancer agents. Journal of Medicinal Chemistry. 53: 7414-27. PMID 20919720 DOI: 10.1021/Jm100884B  0.311
2010 Dirks NL, Meibohm B. Population pharmacokinetics of therapeutic monoclonal antibodies. Clinical Pharmacokinetics. 49: 633-59. PMID 20818831 DOI: 10.2165/11535960-000000000-00000  0.709
2009 Budha NR, Lee RB, Hurdle JG, Lee RE, Meibohm B. A simple in vitro PK/PD model system to determine time-kill curves of drugs against Mycobacteria. Tuberculosis (Edinburgh, Scotland). 89: 378-85. PMID 19748318 DOI: 10.1016/J.Tube.2009.08.002  0.693
2009 Läer S, Barrett JS, Meibohm B. The in silico child: using simulation to guide pediatric drug development and manage pediatric pharmacotherapy. Journal of Clinical Pharmacology. 49: 889-904. PMID 19531673 DOI: 10.1177/0091270009337513  0.346
2008 Dirks NL, Li S, Huth B, Hochhaus G, Yates CR, Meibohm B. Transrepression and transactivation potencies of inhaled glucocorticoids. Die Pharmazie. 63: 893-8. PMID 19177906 DOI: 10.1691/Ph.2008.8638  0.69
2008 Zhang L, Pfister M, Meibohm B. Concepts and challenges in quantitative pharmacology and model-based drug development. The Aaps Journal. 10: 552-9. PMID 19003542 DOI: 10.1208/S12248-008-9062-3  0.349
2008 Zhang Y, Mehrotra N, Budha NR, Christensen ML, Meibohm B. A tandem mass spectrometry assay for the simultaneous determination of acetaminophen, caffeine, phenytoin, ranitidine, and theophylline in small volume pediatric plasma specimens. Clinica Chimica Acta; International Journal of Clinical Chemistry. 398: 105-12. PMID 18796299 DOI: 10.1016/J.Cca.2008.08.023  0.654
2008 Mertens-Talcott SU, Rios J, Jilma-Stohlawetz P, Pacheco-Palencia LA, Meibohm B, Talcott ST, Derendorf H. Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers. Journal of Agricultural and Food Chemistry. 56: 7796-802. PMID 18693743 DOI: 10.1021/Jf8007037  0.303
2008 Hurdle JG, Lee RB, Budha NR, Carson EI, Qi J, Scherman MS, Cho SH, McNeil MR, Lenaerts AJ, Franzblau SG, Meibohm B, Lee RE. A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents. The Journal of Antimicrobial Chemotherapy. 62: 1037-45. PMID 18693235 DOI: 10.1093/Jac/Dkn307  0.671
2008 Budha NR, Mehrotra N, Tangallapally R, Rakesh, Qi J, Daniels AJ, Lee RE, Meibohm B. Pharmacokinetically-guided lead optimization of nitrofuranylamide anti-tuberculosis agents. The Aaps Journal. 10: 157-65. PMID 18446516 DOI: 10.1208/S12248-008-9017-8  0.679
2008 Budha NR, Lee RE, Meibohm B. Biopharmaceutics, pharmacokinetics and pharmacodynamics of antituberculosis drugs. Current Medicinal Chemistry. 15: 809-25. PMID 18393850 DOI: 10.2174/092986708783955509  0.697
2008 Dirks NL, Nolting A, Kovar A, Meibohm B. Population pharmacokinetics of cetuximab in patients with squamous cell carcinoma of the head and neck. Journal of Clinical Pharmacology. 48: 267-78. PMID 18218786 DOI: 10.1177/0091270007313393  0.706
2007 Tangallapally RP, Sun D, Rakesh, Budha N, Lee RE, Lenaerts AJ, Meibohm B, Lee RE. Discovery of novel isoxazolines as anti-tuberculosis agents. Bioorganic & Medicinal Chemistry Letters. 17: 6638-42. PMID 17937983 DOI: 10.1016/J.Bmcl.2007.09.048  0.677
2007 Chen ML, Straughn AB, Sadrieh N, Meyer M, Faustino PJ, Ciavarella AB, Meibohm B, Yates CR, Hussain AS. A modern view of excipient effects on bioequivalence: case study of sorbitol. Pharmaceutical Research. 24: 73-80. PMID 17048115 DOI: 10.1007/S11095-006-9120-4  0.338
2007 Mehrotra N, Gupta M, Kovar A, Meibohm B. The role of pharmacokinetics and pharmacodynamics in phosphodiesterase-5 inhibitor therapy. International Journal of Impotence Research. 19: 253-64. PMID 16988721 DOI: 10.1038/Sj.Ijir.3901522  0.395
2006 Tang L, Meibohm B. Pharmacokinetics of Peptides and Proteins Pharmacokinetics and Pharmacodynamics of Biotech Drugs: Principles and Case Studies in Drug Development. 15-43. DOI: 10.1002/3527600906.Mcb.200400105.Pub2  0.314
2006 Meibohm B, Derendorf H. Pharmacokinetics and Pharmacodynamics of Biotech Drugs Reviews in Cell Biology and Molecular Medicine. 145-172. DOI: 10.1002/3527600906.Mcb.200400105  0.384
2005 Song P, Meibohm B, Yates CR. LC/MS/MS in drug development: targeting the brain. Biotechniques. 19-23. PMID 16528912 DOI: 10.2144/05386Su03  0.339
2005 Meibohm B, Läer S, Panetta JC, Barrett JS. Population pharmacokinetic studies in pediatrics: issues in design and analysis. The Aaps Journal. 7: E475-87. PMID 16353925 DOI: 10.1208/Aapsj070248  0.309
2005 Gupta M, Kovar A, Meibohm B. The clinical pharmacokinetics of phosphodiesterase-5 inhibitors for erectile dysfunction. Journal of Clinical Pharmacology. 45: 987-1003. PMID 16100293 DOI: 10.1177/0091270005276847  0.366
2005 LAER S, ALBERS S, GUPTA M, MIR T, MEIBOHM B. Population pharmacokinetics of carvedilol in pediatric patients with congestive heart failure Clinical Pharmacology & Therapeutics. 77: P88-P88. DOI: 10.1016/J.Clpt.2004.12.229  0.312
2004 Dirks NL, Huth B, Yates CR, Meibohm B. Pharmacokinetics of immunosuppressants: a perspective on ethnic differences. International Journal of Clinical Pharmacology and Therapeutics. 42: 701-18. PMID 15624287  0.703
2004 Tang L, Persky AM, Hochhaus G, Meibohm B. Pharmacokinetic aspects of biotechnology products. Journal of Pharmaceutical Sciences. 93: 2184-204. PMID 15295780 DOI: 10.1002/Jps.20125  0.357
2003 Yates CR, Zhang W, Song P, Li S, Gaber AO, Kotb M, Honaker MR, Alloway RR, Meibohm B. The effect of CYP3A5 and MDR1 polymorphic expression on cyclosporine oral disposition in renal transplant patients. Journal of Clinical Pharmacology. 43: 555-64. PMID 12817518 DOI: 10.1177/0091270003253617  0.318
2002 Meibohm B, Beierle I, Derendorf H. How important are gender differences in pharmacokinetics? Clinical Pharmacokinetics. 41: 329-42. PMID 12036391 DOI: 10.2165/00003088-200241050-00002  0.333
2002 Meibohm B, Derendorf H. Pharmacokinetic/pharmacodynamic studies in drug product development. Journal of Pharmaceutical Sciences. 91: 18-31. PMID 11782894 DOI: 10.1002/Jps.1167  0.368
1999 Meibohm B, Hochhaus G, Möllmann H, Barth J, Wagner M, Krieg M, Stöckmann R, Derendorf H. A pharmacokinetic/pharmacodynamic approach to predict the cumulative cortisol suppression of inhaled corticosteroids Journal of Pharmacokinetics and Biopharmaceutics. 27: 127-147. PMID 10567952 DOI: 10.1023/A:1020670421957  0.342
1999 Derendorf H, Meibohm B. Modeling of pharmacokinetic/pharmacodynamic (PK/PD) relationships: Concepts and perspectives Pharmaceutical Research. 16: 176-185. PMID 10100300 DOI: 10.1023/A:1011907920641  0.35
1998 Derendorf H, Hochhaus G, Meibohm B, Mollmann H, Barth J. Pharmacokinetics and pharmacodynamics of inhaled corticosteroids Journal of Allergy and Clinical Immunology. 101. PMID 9563369 DOI: 10.1016/S0091-6749(98)70156-3  0.316
1998 Möllmann H, Wagner M, Meibohm B, Hochhaus G, Barth J, Stöckmann R, Krieg M, Weisser H, Falcoz C, Derendorf H. Pharmacokinetic and pharmacodynamic evaluation of fluticasone propionate after inhaled administration European Journal of Clinical Pharmacology. 53: 459-467. PMID 9551705 DOI: 10.1007/S002280050407  0.339
1997 Möllmann H, Derendorf H, Barth J, Meibohm B, Wagner M, Krieg M, Weisser H, Knöller J, Möllmann A, Hochhaus G. Pharmacokinetic/pharmacodynamic evaluation of systemic effects of flunisolide after inhalation Journal of Clinical Pharmacology. 37: 893-903. PMID 9505980 DOI: 10.1002/J.1552-4604.1997.Tb04263.X  0.359
1997 Meibohm B, Hochhaus G, Rohatagi S, Möllmann H, Barth J, Wagner M, Krieg M, Stöckmann R, Derendorf H. Dependency of cortisol suppression on administration time of inhaled corticosteroids Journal of Clinical Pharmacology. 37: 704-710. PMID 9378842 DOI: 10.1002/J.1552-4604.1997.Tb04357.X  0.34
1996 Rohatagi S, Bye A, Falcoz C, Mackie AE, Meibohm B, Möllmann H, Derendorf H. Dynamic modeling of cortisol reduction after inhaled administration of fluticasone propionate Journal of Clinical Pharmacology. 36: 938-941. PMID 8930781 DOI: 10.1002/J.1552-4604.1996.Tb04761.X  0.344
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