| Year |
Citation |
Score |
| 2023 |
Chang CH, Cheng TY, Yeh WW, Luo YL, Campbell M, Kuo TC, Shen TW, Hong YC, Tsai CH, Peng YC, Pan CC, Yang MH, Shih JC, Kung HJ, Huang WJ, et al. REST-repressed lncRNA LINC01801 induces neuroendocrine differentiation in prostate cancer via transcriptional activation of autophagy. American Journal of Cancer Research. 13: 3983-4002. PMID 37818052 |
0.346 |
|
| 2022 |
Liu JS, Fang WK, Yang SM, Wu MC, Chen TJ, Chen CM, Lin TY, Liu KL, Wu CM, Chen YC, Chuu CP, Wang LY, Hsieh HP, Kung HJ, Wang WC. Natural product myricetin is a pan-KDM4 inhibitor which with poly lactic-co-glycolic acid formulation effectively targets castration-resistant prostate cancer. Journal of Biomedical Science. 29: 29. PMID 35534851 DOI: 10.1186/s12929-022-00812-3 |
0.342 |
|
| 2021 |
Chen CL, Lin CY, Kung HJ. Targeting Mitochondrial OXPHOS and Their Regulatory Signals in Prostate Cancers. International Journal of Molecular Sciences. 22. PMID 34948229 DOI: 10.3390/ijms222413435 |
0.349 |
|
| 2021 |
Wu MJ, Chen CJ, Lin TY, Liu YY, Tseng LL, Cheng ML, Chuu CP, Tsai HK, Kuo WL, Kung HJ, Wang WC. Targeting KDM4B that coactivates c-Myc-regulated metabolism to suppress tumor growth in castration-resistant prostate cancer. Theranostics. 11: 7779-7796. PMID 34335964 DOI: 10.7150/thno.58729 |
0.308 |
|
| 2021 |
Hsu SC, Chen CL, Cheng ML, Chu CY, Changou CA, Yu YL, Yeh SD, Kuo TC, Kuo CC, Chuu CP, Li CF, Wang LH, Chen HW, Yen Y, Ann DK, ... ... Kung HJ, et al. Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes. Theranostics. 11: 7527-7545. PMID 34158865 DOI: 10.7150/thno.54695 |
0.305 |
|
| 2021 |
Chen CL, Hsu SC, Chung TY, Chu CY, Wang HJ, Hsiao PW, Yeh SD, Ann DK, Yen Y, Kung HJ. Arginine is an epigenetic regulator targeting TEAD4 to modulate OXPHOS in prostate cancer cells. Nature Communications. 12: 2398. PMID 33893278 DOI: 10.1038/s41467-021-22652-9 |
0.368 |
|
| 2020 |
Tseng LL, Cheng HH, Yeh TS, Huang SC, Syu YY, Chuu CP, Yuh CH, Kung HJ, Wang WC. Targeting the histone demethylase PHF8-mediated PKCα-Src-PTEN axis in HER2-negative gastric cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 32958674 DOI: 10.1073/Pnas.1919766117 |
0.384 |
|
| 2020 |
Wu Y, Chen Y, Cheng C, Chi K, Kuo T, Kung H, Ann DK, Kuo C. Abstract P1-05-10: lncRNA UBA6-AS1 participates in the integrated stress response of breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P1-05-10 |
0.33 |
|
| 2019 |
Lin CY, Wang BJ, Chen BC, Tseng JC, Jiang SS, Tsai KK, Shen YY, Yuh CH, Sie ZL, Wang WC, Kung HJ, Chuu CP. Histone Demethylase KDM4C Stimulates the Proliferation of Prostate Cancer Cells via Activation of AKT and c-Myc. Cancers. 11. PMID 31766290 DOI: 10.3390/cancers11111785 |
0.368 |
|
| 2019 |
Wang YH, Huang JT, Chen WL, Wang RH, Kao MC, Pan YR, Chan SH, Tsai KW, Kung HJ, Lin KT, Wang LH. Dysregulation of cystathionine γ-lyase promotes prostate cancer progression and metastasis. Embo Reports. e45986. PMID 31468690 DOI: 10.15252/Embr.201845986 |
0.337 |
|
| 2018 |
Wang HJ, Pochampalli M, Wang LY, Zou JX, Li PS, Hsu SC, Wang BJ, Huang SH, Yang P, Yang JC, Chu CY, Hsieh CL, Sung SY, Li CF, Tepper CG, ... Kung HJ, et al. KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC. Oncogene. PMID 30072740 DOI: 10.1038/S41388-018-0414-X |
0.364 |
|
| 2018 |
Shih TC, Liu R, Wu CT, Li X, Xiao W, Deng X, Kiss Z, Wang T, Chen X, Carney RP, Kung HJ, Duan Y, Ghosh PM, Lam KS. Targeting Galectin-1 impairs castration-resistant prostate cancer progression and invasion. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29666302 DOI: 10.1158/1078-0432.Ccr-18-0157 |
0.46 |
|
| 2018 |
Kuo C, Chang J, Hsieh H, Kung H, Chang H, Huang C, Kuo C, Ke Y. Abstract 3944: Blockage of EGFR signaling repurposes tumor metabolism through suppression of glycolysis and Kreb cycle in head and neck cancer Cancer Research. 78: 3944-3944. DOI: 10.1158/1538-7445.Am2018-3944 |
0.392 |
|
| 2017 |
Shih CH, Chang YJ, Huang WC, Jang TH, Kung HJ, Wang WC, Yang MH, Lin MC, Huang SF, Chou SW, Chang E, Chiu H, Shieh TY, Chen YJ, Wang LH, et al. EZH2-mediated upregulation of ROS1 oncogene promotes oral cancer metastasis. Oncogene. PMID 28759046 DOI: 10.1038/Onc.2017.262 |
0.387 |
|
| 2017 |
Chang YT, Lin TP, Campbell M, Pan CC, Lee SH, Lee HC, Yang MH, Kung HJ, Chang PC. REST is a crucial regulator for acquiring EMT-like and stemness phenotypes in hormone-refractory prostate cancer. Scientific Reports. 7: 42795. PMID 28256535 DOI: 10.1038/srep42795 |
0.33 |
|
| 2017 |
Kuo T, Hsu S, Chou H, Li P, Wu S, Yu Y, Song J, Kung H. Abstract 3502: RNAi screen identified novel long non-coding RNAs involved in cell growth control, migration, and invasion Cancer Research. 77: 3502-3502. DOI: 10.1158/1538-7445.Am2017-3502 |
0.377 |
|
| 2016 |
Wang J, Zou JX, Xue X, Cai D, Zhang Y, Duan Z, Xiang Q, Yang JC, Louie MC, Borowsky AD, Gao AC, Evans CP, Lam KS, Xu J, Kung HJ, et al. Corrigendum: ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer. Nature Medicine. 22: 692. PMID 27270780 DOI: 10.1038/Nm0616-692B |
0.303 |
|
| 2016 |
Lin TP, Chang YT, Lee SY, Campbell M, Wang TC, Shen SH, Chung HJ, Chang YH, Chiu AW, Pan CC, Lin CH, Chu CY, Kung HJ, Cheng CY, Chang PC. REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling. Oncotarget. PMID 27034167 DOI: 10.18632/oncotarget.8433 |
0.34 |
|
| 2016 |
Wang J, Zou JX, Xue X, Cai D, Zhang Y, Duan Z, Xiang Q, Yang JC, Louie MC, Borowsky AD, Gao AC, Evans CP, Lam KS, Xu J, Kung HJ, et al. ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer. Nature Medicine. PMID 27019329 DOI: 10.1038/Nm.4070 |
0.32 |
|
| 2016 |
Wang L, Wang H, Hung C, Wang W, Ann DK, Kung H. Novel Functions of Lysine Demethylases as Mitochondrial Gatekeepers Journal of World Mitochondria Society. 2. DOI: 10.18143/Jwms_V2I2_1974 |
0.404 |
|
| 2016 |
Wang H, Yu Y, Hsu S, Kuo C, Wang W, Shuu C, Kung H. Abstract B48: Epigenetic reprogramming of mitochondrial and metabolic functions plays a key role in arginine-deprivation based cancer therapy Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-B48 |
0.363 |
|
| 2016 |
Wang J, Wang H, Wang L, Cai D, Duan Z, Chen P, Zou JX, Xu J, Chen X, Kung H, Chen H. Abstract 3062: Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy Cancer Research. 76: 3062-3062. DOI: 10.1158/1538-7445.Am2016-3062 |
0.422 |
|
| 2015 |
Shih JW, Wang LY, Hung CL, Kung HJ, Hsieh CL. Non-Coding RNAs in Castration-Resistant Prostate Cancer: Regulation of Androgen Receptor Signaling and Cancer Metabolism. International Journal of Molecular Sciences. 16: 28943-78. PMID 26690121 DOI: 10.3390/ijms161226138 |
0.331 |
|
| 2015 |
Lin HP, Lin CY, Huo C, Jan YJ, Tseng JC, Jiang SS, Kuo YY, Chen SC, Wang CT, Chan TM, Liou JY, Wang J, Chang WW, Chang CH, Kung HJ, et al. Akt3 promotes prostate cancer proliferation cells through regulation of Akt, B-Raf, & TSC1/TSC2. Oncotarget. PMID 26318033 DOI: 10.18632/Oncotarget.4553 |
0.339 |
|
| 2015 |
Lin HP, Lin CY, Huo C, Hsiao PH, Su LC, Jiang SS, Chan TM, Chang CH, Chen LT, Kung HJ, Wang HD, Chuu CP. Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1. Oncotarget. 6: 6684-707. PMID 25788262 |
0.345 |
|
| 2015 |
Lin HP, Lin CY, Huo C, Jan YJ, Tseng JC, Jiang SS, Kuo YY, Chen SC, Wang CT, Chan TM, Liou JY, Wang J, Wayne Chang WS, Chang CH, Kung HJ, et al. AKT3 promotes prostate cancer proliferation cells through regulation of Akt, B-Raf & TSC1/TSC2 Oncotarget. 6: 27097-27112. DOI: 10.18632/oncotarget.4553 |
0.347 |
|
| 2015 |
Wang L, Hung C, Yu Y, Chen H, Srivastava S, Petrovics G, Kung H. Abstract B16: A novel long non-coding RNA connects c-Myc to tumor metabolism Molecular Cancer Research. 13. DOI: 10.1158/1557-3125.Myc15-B16 |
0.444 |
|
| 2015 |
Kuo C, Hsieh H, Kung H. Abstract A171: Targeting tumor metabolism by novel EGFR inhibitor in head and neck cancer Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-A171 |
0.396 |
|
| 2015 |
Lin HP, Lin CY, Huo C, Hsiao PH, Su LC, Jiang SS, Chan TM, Chang CH, Chen LT, Kung HJ, Wang HD, Chuu CP. Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1 Oncotarget. 6: 6684-6707. |
0.347 |
|
| 2014 |
Hung CL, Wang LY, Yu YL, Chen HW, Srivastava S, Petrovics G, Kung HJ. A long noncoding RNA connects c-Myc to tumor metabolism. Proceedings of the National Academy of Sciences of the United States of America. 111: 18697-702. PMID 25512540 DOI: 10.1073/pnas.1415669112 |
0.343 |
|
| 2014 |
Chang PC, Kung HJ. SUMO and KSHV Replication. Cancers. 6: 1905-24. PMID 25268162 DOI: 10.3390/Cancers6041905 |
0.336 |
|
| 2014 |
Guo W, Liu R, Bhardwaj G, Yang JC, Changou C, Ma AH, Mazloom A, Chintapalli S, Xiao K, Xiao W, Kumaresan P, Sanchez E, Yeh CT, Evans CP, Patterson R, ... ... Kung HJ, et al. Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor. Cell Death & Disease. 5: e1409. PMID 25188519 DOI: 10.1038/Cddis.2014.343 |
0.473 |
|
| 2014 |
Chu CH, Wang LY, Hsu KC, Chen CC, Cheng HH, Wang SM, Wu CM, Chen TJ, Li LT, Liu R, Hung CL, Yang JM, Kung HJ, Wang WC. KDM4B as a target for prostate cancer: structural analysis and selective inhibition by a novel inhibitor. Journal of Medicinal Chemistry. 57: 5975-85. PMID 24971742 DOI: 10.1021/jm500249n |
0.36 |
|
| 2014 |
Nguyen HG, Yang JC, Kung HJ, Shi XB, Tilki D, Lara PN, DeVere White RW, Gao AC, Evans CP. Targeting autophagy overcomes Enzalutamide resistance in castration-resistant prostate cancer cells and improves therapeutic response in a xenograft model. Oncogene. 33: 4521-30. PMID 24662833 DOI: 10.1038/Onc.2014.25 |
0.363 |
|
| 2014 |
Chang PC, Wang TY, Chang YT, Chu CY, Lee CL, Hsu HW, Zhou TA, Wu Z, Kim RH, Desai SJ, Liu S, Kung HJ. Autophagy pathway is required for IL-6 induced neuroendocrine differentiation and chemoresistance of prostate cancer LNCaP cells. Plos One. 9: e88556. PMID 24551118 DOI: 10.1371/Journal.Pone.0088556 |
0.705 |
|
| 2014 |
Wang H, Hsieh Y, Cheng W, Lin C, Lin Y, Yang S, Chen C, Izumiya Y, Yu J, Kung H, Wang W. Abstract 3359: JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1α-mediated glucose metabolism Cancer Research. 74: 3359-3359. DOI: 10.1158/1538-7445.Am2014-3359 |
0.354 |
|
| 2014 |
Yang JC, Nguyen HG, Kung H, Shi X, Tilki D, White RWd, Gao AC, Evans CP. Abstract 327: Targeting autophagy overcomes enzalutamide resistance in castrate-resistant prostate cancer cells and improves therapeutic response in a xenograft model Cancer Research. 74: 327-327. DOI: 10.1158/1538-7445.Am2014-327 |
0.463 |
|
| 2014 |
Zou JX, Wang J, Duan Z, Chen H, Kung H, Chen X, Murphy LC, Borowsky A. Abstract 2433: Metabolic reprogramming by an epigenetic mechanism in endocrine therapy resistance of breast cancer Cancer Research. 74: 2433-2433. DOI: 10.1158/1538-7445.Am2014-2433 |
0.375 |
|
| 2013 |
Toth Z, Brulois K, Lee HR, Izumiya Y, Tepper C, Kung HJ, Jung JU. Biphasic euchromatin-to-heterochromatin transition on the KSHV genome following de novo infection. Plos Pathogens. 9: e1003813. PMID 24367262 DOI: 10.1371/Journal.Ppat.1003813 |
0.305 |
|
| 2013 |
Lin HP, Lin CY, Hsiao PH, Wang HD, Sheng Jiang S, Hsu JM, Jim WT, Chen M, Kung HJ, Chuu CP. Difference in protein expression profile and chemotherapy drugs response of different progression stages of LNCaP sublines and other human prostate cancer cells. Plos One. 8: e82625. PMID 24349321 DOI: 10.1371/journal.pone.0082625 |
0.331 |
|
| 2013 |
Guo W, Liu R, Bhardwaj G, Ma AH, Changou C, Yang JC, Li Y, Feng C, Luo Y, Mazloom A, Sanchez E, Wang Y, Huang W, Patterson R, Evans CP, ... ... Kung HJ, et al. CTA095, a novel Etk and Src dual inhibitor, induces apoptosis in prostate cancer cells and overcomes resistance to Src inhibitors. Plos One. 8: e70910. PMID 23967135 DOI: 10.1371/Journal.Pone.0070910 |
0.381 |
|
| 2013 |
Changou CA, Wolfson DL, Ahluwalia BS, Bold RJ, Kung HJ, Chuang FY. Quantitative analysis of autophagy using advanced 3D fluorescence microscopy. Journal of Visualized Experiments : Jove. e50047. PMID 23665532 DOI: 10.3791/50047 |
0.311 |
|
| 2013 |
Li T, Kung HJ, Mack PC, Gandara DR. Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 1039-49. PMID 23401433 DOI: 10.1200/Jco.2012.45.3753 |
0.336 |
|
| 2013 |
Kao C, Martiniez A, Shi X, Dobi A, White RWdV, Kung H. Abstract 4190: miR-30 as a tumor suppressor connects EGF/Src signal to EMT and ERG. Cancer Research. 73: 4190-4190. DOI: 10.1158/1538-7445.Am2013-4190 |
0.408 |
|
| 2013 |
Su C, Chuang C, Wu A, Wang L, Lee W, Wu C, Lam K, Kung H, Yeh C. Abstract 2087: A novel Btk tyrosine kinase inhibitor, CTN06, as a potential candidate agent for breast cancer treatment. Cancer Research. 73: 2087-2087. DOI: 10.1158/1538-7445.Am2013-2087 |
0.392 |
|
| 2013 |
Nguyen HG, Yang JC, Kung H, Gao AC, Evans CP. Abstract 1665: Autophagy is a survival mechanism in mediating resistance to androgen receptor signaling inhibitors in castrate resistant prostate cancer cells. Cancer Research. 73: 1665-1665. DOI: 10.1158/1538-7445.Am2013-1665 |
0.469 |
|
| 2013 |
Changou C, Cheng RH, Bold R, Kung H, Chuang FYS. Microscopic analysis of cell death by metabolic stress-induced autophagy in prostate cancer Proceedings of Spie. 8587. DOI: 10.1117/12.2004759 |
0.409 |
|
| 2012 |
Tsai HC, Boucher DL, Martinez A, Tepper CG, Kung HJ. Modeling truncated AR expression in a natural androgen responsive environment and identification of RHOB as a direct transcriptional target. Plos One. 7: e49887. PMID 23209612 DOI: 10.1371/Journal.Pone.0049887 |
0.691 |
|
| 2012 |
Mooso BA, Vinall RL, Tepper CG, Savoy RM, Cheung JP, Singh S, Siddiqui S, Wang Y, Bedolla RG, Martinez A, Mudryj M, Kung HJ, Devere White RW, Ghosh PM. Enhancing the effectiveness of androgen deprivation in prostate cancer by inducing Filamin A nuclear localization. Endocrine-Related Cancer. 19: 759-77. PMID 22993077 DOI: 10.1530/Erc-12-0171 |
0.443 |
|
| 2012 |
Guo W, Liu R, Ono Y, Ma AH, Martinez A, Sanchez E, Wang Y, Huang W, Mazloom A, Li J, Ning J, Maverakis E, Lam KS, Kung HJ. Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs. Molecular Pharmacology. 82: 938-47. PMID 22899868 DOI: 10.1124/Mol.112.079889 |
0.368 |
|
| 2012 |
Yang P, Guo L, Duan ZJ, Tepper CG, Xue L, Chen X, Kung HJ, Gao AC, Zou JX, Chen HW. Histone methyltransferase NSD2/MMSET mediates constitutive NF-κB signaling for cancer cell proliferation, survival, and tumor growth via a feed-forward loop. Molecular and Cellular Biology. 32: 3121-31. PMID 22645312 DOI: 10.1128/Mcb.00204-12 |
0.381 |
|
| 2012 |
Nadiminty N, Tummala R, Lou W, Zhu Y, Shi XB, Zou JX, Chen H, Zhang J, Chen X, Luo J, deVere White RW, Kung HJ, Evans CP, Gao AC. MicroRNA let-7c is downregulated in prostate cancer and suppresses prostate cancer growth. Plos One. 7: e32832. PMID 22479342 DOI: 10.1371/Journal.Pone.0032832 |
0.304 |
|
| 2012 |
Yamashita S, Lai KP, Chuang KL, Xu D, Miyamoto H, Tochigi T, Pang ST, Li L, Arai Y, Kung HJ, Yeh S, Chang C. ASC-J9 suppresses castration-resistant prostate cancer growth through degradation of full-length and splice variant androgen receptors. Neoplasia (New York, N.Y.). 14: 74-83. PMID 22355276 DOI: 10.1593/Neo.111436 |
0.335 |
|
| 2012 |
Nadiminty N, Tummala R, Lou W, Zhu Y, Zhang J, Chen X, eVere White RW, Kung HJ, Evans CP, Gao AC. MicroRNA let-7c suppresses androgen receptor expression and activity via regulation of Myc expression in prostate cancer cells. The Journal of Biological Chemistry. 287: 1527-37. PMID 22128178 DOI: 10.1074/Jbc.M111.278705 |
0.444 |
|
| 2012 |
Wang L, Kung H. Male germ cell-associated kinase is overexpressed in prostate cancer cells and causes mitotic defects via deregulation of APC/C CDH1 Oncogene. 31: 2907-2918. PMID 21986944 DOI: 10.1038/Onc.2011.464 |
0.467 |
|
| 2012 |
Bai L, Yang JC, Ok JH, Mack PC, Kung HJ, Evans CP. Simultaneous targeting of Src kinase and receptor tyrosine kinase results in synergistic inhibition of renal cell carcinoma proliferation and migration. International Journal of Cancer. 130: 2693-702. PMID 21792888 DOI: 10.1002/Ijc.26303 |
0.391 |
|
| 2012 |
Yang JC, Hu B, Durbin-Johnson B, Gao AC, Kung H, Evans CP. Abstract 1800: Targeted therapy using saracatinib adjunctive to castration inhibits progression to castration-resistant prostate cancer in a murine model Cancer Research. 72: 1800-1800. DOI: 10.1158/1538-7445.Am2012-1800 |
0.435 |
|
| 2012 |
Yang J, Hu B, Gao A, Kung H, Durbin-Johnson B, Evans C. 792 Targeted Therapy Using Saracatinib Adjunctive To Castration Inhibits Progression To Castration Resistant Prostate Cancer In A Murine Model The Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.880 |
0.407 |
|
| 2012 |
Yamashita S, Lai K, Chuang K, Miyamoto H, Tochigi T, Pang S, Li L, Arai Y, Kung H, Yeh S, Chang C. 960 ASC-J9® SUPPRESSES CASTRATION-RESISTANT PROSTATE CANCER GROWTH VIA DEGRADATION OF FULL-LENGTH AND SPLICE VARIANT ANDROGEN RECEPTORS Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.1059 |
0.417 |
|
| 2011 |
Kung HJ. Targeting tyrosine kinases and autophagy in prostate cancer. Hormones & Cancer. 2: 38-46. PMID 21350583 DOI: 10.1007/s12672-010-0053-3 |
0.392 |
|
| 2011 |
Mudryj M, Libertini SJ, Chen H, Al-Bataina B, Kung H, Ghosh PM. Abstract 4541: Binding and transcriptional activity of the androgen receptor isoforms in 22Rv1 prostate cancer cells Cancer Research. 71: 4541-4541. DOI: 10.1158/1538-7445.Am2011-4541 |
0.44 |
|
| 2011 |
Yang JC, Kung H, Gao AC, Evans CP. Abstract 359: Neuropeptides promote castration-resistant prostate cancer through intracrine androgen biosynthesis Endocrinology. 71: 359-359. DOI: 10.1158/1538-7445.Am2011-359 |
0.406 |
|
| 2011 |
Liu R, Guo W, Ma A, Sanchez E, Wang Y, Li J, Xu C, Ning J, Huang W, Mazloom A, Song A, Lam KS, Xia M, Chen Y, Kung H. Abstract 3580: Discovery and SAR study of a novel and potent Itk inhibitor as a targeted therapeutic agent for T-cell lymphoma and leukemia Cancer Research. 71: 3580-3580. DOI: 10.1158/1538-7445.Am2011-3580 |
0.409 |
|
| 2011 |
Evans C, Yang J, Kung H, Gao A. 272 Neuropeptides Promote Castration Resistant Prostate Cancer Through Intracrine Androgen Biosynthesis The Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.364 |
0.407 |
|
| 2010 |
Wu Z, Chang PC, Yang JC, Chu CY, Wang LY, Chen NT, Ma AH, Desai SJ, Lo SH, Evans CP, Lam KS, Kung HJ. Autophagy Blockade Sensitizes Prostate Cancer Cells towards Src Family Kinase Inhibitors. Genes & Cancer. 1: 40-9. PMID 20811583 DOI: 10.1177/1947601909358324 |
0.679 |
|
| 2010 |
Chen H, Libertini SJ, George M, Dandekar S, Tepper CG, Al-Bataina B, Kung HJ, Ghosh PM, Mudryj M. Genome-wide analysis of androgen receptor binding and gene regulation in two CWR22-derived prostate cancer cell lines. Endocrine-Related Cancer. 17: 857-73. PMID 20634343 DOI: 10.1677/Erc-10-0081 |
0.442 |
|
| 2010 |
Yang JC, Bai L, Yap S, Gao AC, Kung HJ, Evans CP. Effect of the specific Src family kinase inhibitor saracatinib on osteolytic lesions using the PC-3 bone model. Molecular Cancer Therapeutics. 9: 1629-37. PMID 20484016 DOI: 10.1158/1535-7163.MCT-09-1058 |
0.327 |
|
| 2010 |
Nadiminty N, Lou W, Sun M, Chen J, Yue J, Kung HJ, Evans CP, Zhou Q, Gao AC. Aberrant activation of the androgen receptor by NF-kappaB2/p52 in prostate cancer cells. Cancer Research. 70: 3309-19. PMID 20388792 DOI: 10.1158/0008-5472.CAN-09-3703 |
0.313 |
|
| 2010 |
Khan IH, Zhao J, Ghosh P, Ziman M, Sweeney C, Kung HJ, Luciw PA. Microbead arrays for the analysis of ErbB receptor tyrosine kinase activation and dimerization in breast cancer cells. Assay and Drug Development Technologies. 8: 27-36. PMID 20035613 DOI: 10.1089/Adt.2009.0208 |
0.401 |
|
| 2010 |
Chen H, Libertini SJ, Wang Y, Kung HJ, Ghosh P, Mudryj M. ERK regulates calpain 2-induced androgen receptor proteolysis in CWR22 relapsed prostate tumor cell lines. The Journal of Biological Chemistry. 285: 2368-74. PMID 19946123 DOI: 10.1074/Jbc.M109.049379 |
0.429 |
|
| 2010 |
Rodriguez CO, Fascetti AJ, Yu Z, Shentu S, Bold RJ, Kung H, Stellrecht CM. Abstract 4848: Pegylated arginine deiminase induces autophagy in canine melanoma and canine osteosarcoma Cancer Research. 70: 4848-4848. DOI: 10.1158/1538-7445.Am10-4848 |
0.384 |
|
| 2010 |
Wu Z, Chang P, Yang JC, Chu C, Wang L, Chen N, Ma A, Desai SJ, Lo SH, Evans CP, Lam KS, Kung H. Abstract 4684: Autophagy blockade sensitizes prostate cancer cells towards Src family kinase inhibitors Cancer Research. 70: 4684-4684. DOI: 10.1158/1538-7445.Am10-4684 |
0.701 |
|
| 2010 |
Chun YY, Nadiminty N, Lou W, Yang J, Evans CP, Kung H, Gao AC. Abstract 1727: Interleukin-6 and intracrine androgens in prostate cancer cells Cancer Research. 70: 1727-1727. DOI: 10.1158/1538-7445.Am10-1727 |
0.417 |
|
| 2010 |
Guo Z, Yang X, Sun F, Linn DE, Jiang R, Chen H, Chen H, Kong X, Melamed J, Tepper CG, Kung H, Brodie AMH, Edwards J, Qiu Y. Abstract 1712: Androgen receptor splicing variants promote therapeutic resistance in prostate cancer Cancer Research. 70: 1712-1712. DOI: 10.1158/1538-7445.Am10-1712 |
0.467 |
|
| 2009 |
Chun JY, Nadiminty N, Dutt S, Lou W, Yang JC, Kung HJ, Evans CP, Gao AC. Interleukin-6 regulates androgen synthesis in prostate cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 4815-22. PMID 19638459 DOI: 10.1158/1078-0432.Ccr-09-0640 |
0.452 |
|
| 2009 |
Zou JX, Guo L, Revenko AS, Tepper CG, Gemo AT, Kung HJ, Chen HW. Androgen-induced coactivator ANCCA mediates specific androgen receptor signaling in prostate cancer. Cancer Research. 69: 3339-46. PMID 19318566 DOI: 10.1158/0008-5472.CAN-08-3440 |
0.387 |
|
| 2009 |
Kim RH, Bold RJ, Kung HJ. ADI, autophagy and apoptosis: metabolic stress as a therapeutic option for prostate cancer. Autophagy. 5: 567-8. PMID 19276647 DOI: 10.4161/auto.5.4.8252 |
0.581 |
|
| 2009 |
Guo Z, Yang X, Sun F, Jiang R, Linn DE, Chen H, Chen H, Kong X, Melamed J, Tepper CG, Kung HJ, Brodie AM, Edwards J, Qiu Y. A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer Research. 69: 2305-13. PMID 19244107 DOI: 10.1158/0008-5472.Can-08-3795 |
0.348 |
|
| 2009 |
Kim RH, Coates JM, Bowles TL, McNerney GP, Sutcliffe J, Jung JU, Gandour-Edwards R, Chuang FY, Bold RJ, Kung HJ. Arginine deiminase as a novel therapy for prostate cancer induces autophagy and caspase-independent apoptosis. Cancer Research. 69: 700-8. PMID 19147587 DOI: 10.1158/0008-5472.Can-08-3157 |
0.584 |
|
| 2009 |
Yang JC, Ok JH, Busby JE, Borowsky AD, Kung HJ, Evans CP. Aberrant activation of androgen receptor in a new neuropeptide-autocrine model of androgen-insensitive prostate cancer. Cancer Research. 69: 151-60. PMID 19117998 DOI: 10.1158/0008-5472.Can-08-0442 |
0.401 |
|
| 2009 |
Kung HJ, Evans CP. Oncogenic activation of androgen receptor. Urologic Oncology. 27: 48-52. PMID 19111798 DOI: 10.1016/j.urolonc.2008.06.002 |
0.322 |
|
| 2009 |
Yang JC, Chun JY, Kung H, Gao AC, Evans CP. Src Family Kinase Inhibitor Azd0530 Inhibits Grp-Mediated Androgen-Independent Growth And Migration Possibly Through Both Androgen And Androgen Receptor The Journal of Urology. 181: 259-259. DOI: 10.1016/S0022-5347(09)60739-4 |
0.388 |
|
| 2009 |
Chun Y, Yang JC, Kung H, Evans CP, Gao AC. Interleukin-6 Enhances Intratumoral Androgen Levels By Regulating The Expression Of Genes Mediating Androgen Metabolism The Journal of Urology. 181: 96-96. DOI: 10.1016/S0022-5347(09)60274-3 |
0.336 |
|
| 2008 |
Martinez HD, Jasavala RJ, Hinkson I, Fitzgerald LD, Trimmer JS, Kung HJ, Wright ME. RNA editing of androgen receptor gene transcripts in prostate cancer cells. The Journal of Biological Chemistry. 283: 29938-49. PMID 18708348 DOI: 10.1074/jbc.M800534200 |
0.3 |
|
| 2008 |
Chang YM, Bai L, Liu S, Yang JC, Kung HJ, Evans CP. Src family kinase oncogenic potential and pathways in prostate cancer as revealed by AZD0530 Oncogene. 27: 6365-6375. PMID 18679417 DOI: 10.1038/Onc.2008.250 |
0.502 |
|
| 2008 |
Bowles TL, Kim R, Galante J, Parsons CM, Virudachalam S, Kung HJ, Bold RJ. Pancreatic cancer cell lines deficient in argininosuccinate synthetase are sensitive to arginine deprivation by arginine deiminase. International Journal of Cancer. Journal International Du Cancer. 123: 1950-5. PMID 18661517 DOI: 10.1002/Ijc.23723 |
0.589 |
|
| 2008 |
Devlin HL, Mack PC, Burich RA, Gumerlock PH, Kung HJ, Mudryj M, deVere White RW. Impairment of the DNA repair and growth arrest pathways by p53R2 silencing enhances DNA damage-induced apoptosis in a p53-dependent manner in prostate cancer cells. Molecular Cancer Research : McR. 6: 808-18. PMID 18505925 DOI: 10.1158/1541-7786.MCR-07-2027 |
0.36 |
|
| 2008 |
Gautschi O, Tepper CG, Purnell PR, Izumiya Y, Evans CP, Green TP, Desprez PY, Lara PN, Gandara DR, Mack PC, Kung HJ. Regulation of Id1 expression by SRC: implications for targeting of the bone morphogenetic protein pathway in cancer. Cancer Research. 68: 2250-8. PMID 18381431 DOI: 10.1158/0008-5472.CAN-07-6403 |
0.333 |
|
| 2008 |
Yang JC, Bai L, Kung H, Evans CP. Effect Of The Specific Src Kinase Inhibitor Azd0530 On Osteolytic Lesions In Prostate Cancer The Journal of Urology. 179: 391-391. DOI: 10.1016/S0022-5347(08)61145-3 |
0.414 |
|
| 2008 |
Bai L, Yang JC, Mack PC, Kung H, Evans CP. TARGETING SRC AND MULTIPLE RECEPTOR TYROSINE KINASES (RTKs) SIMULTANEOUSLY RESULTED IN SYNERGISTIC INHIBITION OF PROLIFERATION AND SUPERIOR REDUCTION OF MIGRATION OF RENAL CANCER CELLS The Journal of Urology. 179: 34-35. DOI: 10.1016/S0022-5347(08)60105-6 |
0.381 |
|
| 2007 |
Libertini SJ, Tepper CG, Rodriguez V, Asmuth DM, Kung HJ, Mudryj M. Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence. Cancer Research. 67: 9001-5. PMID 17909000 DOI: 10.1158/0008-5472.Can-07-1072 |
0.366 |
|
| 2007 |
Chang YM, Kung HJ, Evans CP. Nonreceptor tyrosine kinases in prostate cancer. Neoplasia (New York, N.Y.). 9: 90-100. PMID 17357254 DOI: 10.1593/Neo.06694 |
0.432 |
|
| 2007 |
Shi XB, Xue L, Tepper CG, Gandour-Edwards R, Ghosh P, Kung HJ, DeVere White RW. The oncogenic potential of a prostate cancer-derived androgen receptor mutant. The Prostate. 67: 591-602. PMID 17262801 DOI: 10.1002/Pros.20544 |
0.413 |
|
| 2007 |
Nair SS, Guo Z, Mueller JM, Koochekpour S, Qiu Y, Tekmal RR, Schüle R, Kung HJ, Kumar R, Vadlamudi RK. Proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor enhances androgen receptor functions through LIM-only coactivator, four-and-a-half LIM-only protein 2. Molecular Endocrinology (Baltimore, Md.). 21: 613-24. PMID 17192406 DOI: 10.1210/Me.2006-0269 |
0.325 |
|
| 2007 |
Vinall RL, Hwa K, Liu S, Kung H, White RWd. 1123: Defining the Signaling Mechanism and Relevance of H2 Relaxin in Prostate Cancer Progression The Journal of Urology. 177: 371-371. DOI: 10.1016/S0022-5347(18)31337-5 |
0.384 |
|
| 2007 |
Yang JC, Chang Y, Bai L, Kung H, Evans CP. 659: Inhibition of Neuropetide-Mediated Prostate Cancer Progression by Specific SRC Kinase Inhibitor AZD0530 The Journal of Urology. 177: 221-222. DOI: 10.1016/S0022-5347(18)30899-1 |
0.448 |
|
| 2007 |
Chang Y, Bai L, Yang JC, Kung H, Evans CP. 532: AZD0530 is a Novel SRC Kinase Inhibitor with Anti-Proliferation and Anti-Migration Properties in Prostate Cancer The Journal of Urology. 177: 177-177. DOI: 10.1016/S0022-5347(18)30772-9 |
0.42 |
|
| 2006 |
Desai SJ, Ma AH, Tepper CG, Chen HW, Kung HJ. Inappropriate activation of the androgen receptor by nonsteroids: involvement of the Src kinase pathway and its therapeutic implications. Cancer Research. 66: 10449-59. PMID 17079466 DOI: 10.1158/0008-5472.Can-06-2582 |
0.674 |
|
| 2006 |
Ma AH, Xia L, Desai SJ, Boucher DL, Guan Y, Shih HM, Shi XB, deVere White RW, Chen HW, Tepper CG, Kung HJ. Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells. Cancer Research. 66: 8439-47. PMID 16951154 DOI: 10.1158/0008-5472.Can-06-1636 |
0.708 |
|
| 2006 |
Zou JX, Zhong Z, Shi XB, Tepper CG, deVere White RW, Kung HJ, Chen H. ACTR/AIB1/SRC-3 and androgen receptor control prostate cancer cell proliferation and tumor growth through direct control of cell cycle genes. The Prostate. 66: 1474-86. PMID 16921507 DOI: 10.1002/Pros.20477 |
0.379 |
|
| 2006 |
Dai B, Kim O, Xie Y, Guo Z, Xu K, Wang B, Kong X, Melamed J, Chen H, Bieberich CJ, Borowsky AD, Kung HJ, Wei G, Ostrowski MC, Brodie A, et al. Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse. Cancer Research. 66: 8058-64. PMID 16912182 DOI: 10.1158/0008-5472.Can-06-1364 |
0.365 |
|
| 2006 |
Evans CP, Lara PN, Kung H, Yang JC. Activity of the Src-kinase inhibitor AZD0530 in androgen-independent prostate cancer (AIPC): Pre-clinical rationale for a phase II trial Journal of Clinical Oncology. 24: 14542-14542. DOI: 10.1200/Jco.2006.24.18_Suppl.14542 |
0.449 |
|
| 2006 |
Yang JC, Bai L, Kung H, Evans CP. 409: Androgen-Sensitive Prostate Cancer Survival and Progression is Supported by Neuroendocrine Prostate Cancer Cells The Journal of Urology. 175: 133-134. DOI: 10.1016/S0022-5347(18)32665-X |
0.423 |
|
| 2005 |
Tepper CG, Gregg JP, Shi XB, Vinall RL, Baron CA, Ryan PE, Desprez PY, Kung HJ, deVere White RW. Profiling of gene expression changes caused by p53 gain-of-function mutant alleles in prostate cancer cells. The Prostate. 65: 375-89. PMID 16037992 DOI: 10.1002/Pros.20308 |
0.419 |
|
| 2005 |
Kamil JP, Tischer BK, Trapp S, Nair VK, Osterrieder N, Kung HJ. vLIP, a viral lipase homologue, is a virulence factor of Marek's disease virus. Journal of Virology. 79: 6984-96. PMID 15890938 DOI: 10.1128/Jvi.79.11.6984-6996.2005 |
0.608 |
|
| 2005 |
Mayeur GL, Kung WJ, Martinez A, Izumiya C, Chen DJ, Kung HJ. Ku is a novel transcriptional recycling coactivator of the androgen receptor in prostate cancer cells. The Journal of Biological Chemistry. 280: 10827-33. PMID 15640154 DOI: 10.1074/Jbc.M413336200 |
0.317 |
|
| 2005 |
Yang JC, Busby E, Kung H, Evans CP. 464: SRC Kinase Inhibition of Neuropeptide-Induced Androgen-Independent Prostate Cancer The Journal of Urology. 173: 127-127. DOI: 10.1016/S0022-5347(18)34717-7 |
0.455 |
|
| 2004 |
Lin DY, Fang HI, Ma AH, Huang YS, Pu YS, Jenster G, Kung HJ, Shih HM. Negative modulation of androgen receptor transcriptional activity by Daxx. Molecular and Cellular Biology. 24: 10529-41. PMID 15572661 DOI: 10.1128/MCB.24.24.10529-10541.2004 |
0.333 |
|
| 2004 |
Wu YM, Robinson DR, Kung HJ. Signal pathways in up-regulation of chemokines by tyrosine kinase MER/NYK in prostate cancer cells. Cancer Research. 64: 7311-20. PMID 15492251 DOI: 10.1158/0008-5472.CAN-04-0972 |
0.359 |
|
| 2004 |
Jiang T, Guo Z, Dai B, Kang M, Ann DK, Kung HJ, Qiu Y. Bi-directional regulation between tyrosine kinase Etk/BMX and tumor suppressor p53 in response to DNA damage. The Journal of Biological Chemistry. 279: 50181-9. PMID 15355990 DOI: 10.1074/Jbc.M409108200 |
0.311 |
|
| 2004 |
Shi XB, Ma AH, Tepper CG, Xia L, Gregg JP, Gandour-Edwards R, Mack PC, Kung HJ, deVere White RW. Molecular alterations associated with LNCaP cell progression to androgen independence. The Prostate. 60: 257-71. PMID 15176055 DOI: 10.1002/pros.20039 |
0.323 |
|
| 2004 |
Lee LF, Louie MC, Desai SJ, Yang J, Chen HW, Evans CP, Kung HJ. Interleukin-8 confers androgen-independent growth and migration of LNCaP: differential effects of tyrosine kinases Src and FAK. Oncogene. 23: 2197-205. PMID 14767470 DOI: 10.1038/Sj.Onc.1207344 |
0.664 |
|
| 2004 |
Yang JC, Chang Y, Lee L, Louie M, Desai S, Busby JE, Kung H, Evans CP. 1090: Interleukin-8 Stimulates Androgen-Independent Growth of Androgen Dependent LNCaP Cells Journal of Urology. 171: 287-287. DOI: 10.1016/S0022-5347(18)38327-7 |
0.647 |
|
| 2003 |
Busby JE, Shih SJ, Yang JC, Kung HJ, Evans CP. Angiogenesis is not mediated by prostate cancer neuropeptides Angiogenesis. 6: 289-293. PMID 15166497 DOI: 10.1023/B:Agen.0000029409.94626.64 |
0.459 |
|
| 2003 |
Lee LF, Liu JL, Cui XP, Kung HJ. Marek's disease virus latent protein MEQ: delineation of an epitope in the BR1 domain involved in nuclear localization. Virus Genes. 27: 211-8. PMID 14618081 DOI: 10.1023/A:1026334130092 |
0.308 |
|
| 2003 |
Yustein JT, Xia L, Kahlenburg JM, Robinson D, Templeton D, Kung H. Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38 Oncogene. 22: 6129-6141. PMID 13679851 DOI: 10.1038/Sj.Onc.1206605 |
0.329 |
|
| 2002 |
Mao TK, Kimura Y, Kenny TP, Branch A, Gish RG, Water JAVd, Kung H, Friedman SL, Gershwin ME. Elevated expression of tyrosine kinase DDR2 in primary biliary cirrhosis. Autoimmunity. 35: 521-529. PMID 12765478 DOI: 10.1080/0891693021000057784 |
0.325 |
|
| 2002 |
Tepper CG, Boucher DL, Ryan PE, Ma AH, Xia L, Lee LF, Pretlow TG, Kung HJ. Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line. Cancer Research. 62: 6606-14. PMID 12438256 |
0.31 |
|
| 2002 |
Okada T, Lian Z, Hsu T, Naiki M, Ansari AA, Robinson D, Kung H, Boyd RL, Gershwin ME. Elevated C-met in thymic dendritic cells of New Zealand Black mice. Developmental Immunology. 9: 29-34. PMID 12353660 DOI: 10.1080/1044667021000003943 |
0.313 |
|
| 2002 |
Huang CY, Wu YM, Hsu CY, Lee WS, Lai MD, Lu TJ, Huang CL, Leu TH, Shih HM, Fang HI, Robinson DR, Kung HJ, Yuan CJ. Caspase activation of mammalian sterile 20-like kinase 3 (Mst3). Nuclear translocation and induction of apoptosis. The Journal of Biological Chemistry. 277: 34367-74. PMID 12107159 DOI: 10.1074/Jbc.M202468200 |
0.347 |
|
| 2002 |
Xia L, Robinson D, Ma AH, Chen HC, Wu F, Qiu Y, Kung HJ. Identification of human male germ cell-associated kinase, a kinase transcriptionally activated by androgen in prostate cancer cells. The Journal of Biological Chemistry. 277: 35422-33. PMID 12084720 DOI: 10.1074/Jbc.M203940200 |
0.487 |
|
| 2002 |
Shi XB, Ma AH, Xia L, Kung HJ, de Vere White RW. Functional analysis of 44 mutant androgen receptors from human prostate cancer. Cancer Research. 62: 1496-502. PMID 11888926 |
0.304 |
|
| 2001 |
Lee LF, Guan J, Qiu Y, Kung HJ. Neuropeptide-induced androgen independence in prostate cancer cells: roles of nonreceptor tyrosine kinases Etk/Bmx, Src, and focal adhesion kinase. Molecular and Cellular Biology. 21: 8385-97. PMID 11713275 DOI: 10.1128/Mcb.21.24.8385-8397.2001 |
0.502 |
|
| 2001 |
Liu HC, Kung HJ, Fulton JE, Morgan RW, Cheng HH. Growth hormone interacts with the Marek's disease virus SORF2 protein and is associated with disease resistance in chicken. Proceedings of the National Academy of Sciences of the United States of America. 98: 9203-8. PMID 11470922 DOI: 10.1038/87186 |
0.321 |
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| 2001 |
Kung HJ, Xia L, Brunovskis P, Li D, Liu JL, Lee LF. Meq: an MDV-specific bZIP transactivator with transforming properties. Current Topics in Microbiology and Immunology. 255: 245-60. PMID 11217425 DOI: 10.1007/978-3-642-56863-3_10 |
0.367 |
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| 2000 |
Liu J, Kung H. Marek's disease herpesvirus transforming protein MEQ: a c-Jun analogue with an alternative life style. Virus Genes. 21: 51-64. DOI: 10.1023/A:1008132313289 |
0.356 |
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| 1999 |
Liu JL, Ye Y, Qian Z, Qian Y, Templeton DJ, Lee LF, Kung HJ. Functional interactions between herpesvirus oncoprotein MEQ and cell cycle regulator CDK2. Journal of Virology. 73: 4208-19. PMID 10196317 DOI: 10.1128/Jvi.73.5.4208-4219.1999 |
0.374 |
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| 1998 |
Qiu Y, Robinson D, Pretlow TG, Kung H. Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3′-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells Proceedings of the National Academy of Sciences of the United States of America. 95: 3644-3649. PMID 9520419 DOI: 10.1073/Pnas.95.7.3644 |
0.419 |
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| 1997 |
Witter RL, Li D, Jones D, Lee LF, Kung H. Retroviral insertional mutagenesis of a herpesvirus: a Marek's disease virus mutant attenuated for oncogenicity but not for immunosuppression or in vivo replication. Avian Diseases. 41: 407-421. DOI: 10.2307/1592197 |
0.305 |
|
| 1995 |
Chang CM, Shu HK, Ravi L, Pelley RJ, Shu H, Kung HJ. A minor tyrosine phosphorylation site located within the CAIN domain plays a critical role in regulating tissue-specific transformation by erbB kinase. Journal of Virology. 69: 1172-80. PMID 7815495 DOI: 10.1128/Jvi.69.2.1172-1180.1995 |
0.344 |
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| 1995 |
Qian Z, Brunovskis P, Rauscher F, Lee L, Kung H. Transactivation activity of Meq, a Marek's disease herpesvirus bZIP protein persistently expressed in latently infected transformed T cells. Journal of Virology. 69: 4037-4044. PMID 7769661 DOI: 10.1128/Jvi.69.7.4037-4044.1995 |
0.355 |
|
| 1995 |
Carter TH, Dominguez N, Zeng L, Kung H. Resistance to transformation by insertionally activated c-erbB is a dominant phenotype in fibroblasts. Virology. 212: 277-283. PMID 7676646 DOI: 10.1006/Viro.1995.1484 |
0.363 |
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| 1995 |
Sui D, Wu P, Kung H, Lee LF. Identification and characterization of a Marek's disease virus gene encoding DNA polymerase☆ Virus Research. 36: 269-278. PMID 7653104 DOI: 10.1016/0168-1702(94)00114-R |
0.313 |
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| 1994 |
Carter TH, Kung HJ. Tissue-specific transformation by oncogenic mutants of epidermal growth factor receptor Critical Reviews in Oncogenesis. 5: 389-428. PMID 7711115 DOI: 10.1615/Critrevoncog.V5.I4.40 |
0.349 |
|
| 1993 |
Lee C, Lee E, Tsai S, Kung H, Liu Y, Hwang J. An EGF-pseudomonas exotoxin A recombinant protein with a deletion in toxin binding domain specifically kills EGF receptor bearing cells Protein Engineering. 6: 433-440. PMID 8332601 DOI: 10.1093/Protein/6.4.433 |
0.354 |
|
| 1992 |
Jones D, Lee L, Liu JL, Kung H, Tillotson JK. Marek disease virus encodes a basic-leucine zipper gene resembling the fos/jun oncogenes that is highly expressed in lymphoblastoid tumors. Proceedings of the National Academy of Sciences of the United States of America. 89: 4042-4046. PMID 1315048 DOI: 10.1073/Pnas.89.9.4042 |
0.342 |
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| 1991 |
Shu HKG, Pelley RJ, Kung H. Dissecting the activating mutations in v-erbB of avian erythroblastosis virus strain R. Journal of Virology. 65: 6173-6180. PMID 1681117 DOI: 10.1128/Jvi.65.11.6173-6180.1991 |
0.342 |
|
| 1991 |
Pain B, Woods CM, Saez J, Flickinger T, Raines M, Peyroll S, Moscovici C, Moscovici MG, Kung HJ, Jurdic P, Lazarides E, Samarut J. EGF-R as a hemopoietic growth factor receptor: The c-erbB product is present in chicken erythrocytic progenitors and controls their self-renewal Cell. 65: 37-46. PMID 1672832 DOI: 10.1016/0092-8674(91)90405-N |
0.329 |
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| 1991 |
Maihle NJ, Flickinger TW, Raines MA, Sanders ML, Kung HJ. Native avian c-erbB gene expresses a secreted protein product corresponding to the ligand-binding domain of the receptor. Proceedings of the National Academy of Sciences of the United States of America. 88: 1825-9. PMID 1672045 DOI: 10.1073/Pnas.88.5.1825 |
0.314 |
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| 1990 |
Antczak M, Kung H. Transformation of chicken embryo fibroblasts by direct DNA transfection of single oncogenes: comparative analyses of src, erbB, myc, and ras. Journal of Virology. 64: 1451-1458. PMID 2181153 DOI: 10.1128/Jvi.64.4.1451-1458.1990 |
0.332 |
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| 1990 |
Shu HKG, Pelley RJ, Kung H. Tissue-specific transformation by epidermal growth factor receptor: a single point mutation within the ATP-binding pocket of the erbB product increases its intrinsic kinase activity and activates its sarcomagenic potential. Proceedings of the National Academy of Sciences of the United States of America. 87: 9103-9107. PMID 1979168 DOI: 10.1073/Pnas.87.23.9103 |
0.35 |
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| 1989 |
Pelley RJ, Maihle NJ, Boerkoel C, Shu HK, Carter TH, Moscovici C, Kung HJ. Disease tropism of c-erbB: Effects of carboxyl-terminal tyrosine and internal mutations on tissue-specific transformation Proceedings of the National Academy of Sciences of the United States of America. 86: 7164-7168. PMID 2550929 DOI: 10.1073/Pnas.86.18.7164 |
0.335 |
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| 1988 |
Maihle NJ, Raines MA, Flickinger TW, Kung H. Proviral insertional activation of c-erbB: Differential processing of the protein products arising from two alternate transcripts Molecular and Cellular Biology. 8: 4868-4876. PMID 3062371 DOI: 10.1128/mcb.8.11.4868-4876.1988 |
0.31 |
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| 1988 |
Raines MA, Maihle NJ, Moscovici C, Crittenden L, Kung H. Mechanism of c-erbB transduction: newly released transducing viruses retain poly(A) tracts of erbB transcripts and encode C-terminally intact erbB proteins. Journal of Virology. 62: 2437-2443. PMID 2897475 DOI: 10.1128/Jvi.62.7.2437-2443.1988 |
0.343 |
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| 1988 |
Raines MA, Maihle NJ, Moscovici C, Moscovici MG, Kung H. Molecular characterization of three erbB transducing viruses generated during avian leukosis virus-induced erythroleukemia: extensive internal deletion near the kinase domain activates the fibrosarcoma- and hemangioma-inducing potentials of erbB. Journal of Virology. 62: 2444-2452. PMID 2836624 DOI: 10.1128/Jvi.62.7.2444-2452.1988 |
0.343 |
|
| 1988 |
Pelley RJ, Moscovici C, Hughes S, Kung H. Proviral-activated c-erbB is leukemogenic but not sarcomagenic: characterization of a replication-competent retrovirus containing the activated c-erbB. Journal of Virology. 62: 1840-1844. PMID 2833627 DOI: 10.1128/Jvi.62.5.1840-1844.1988 |
0.315 |
|
| 1987 |
Tanaka A, Gibbs CP, Arthur RR, Anderson SK, Kung H, Fujita DJ. DNA sequence encoding the amino-terminal region of the human c-src protein: implications of sequence divergence among src-type kinase oncogenes Molecular and Cellular Biology. 7: 1978-1983. PMID 3299057 DOI: 10.1128/mcb.7.5.1978-1983.1987 |
0.308 |
|
| 1987 |
Swift RA, Boerkoel C, Ridgway A, Fujita DJ, Dodgson JB, Kung HJ. B-lymphoma induction by reticuloendotheliosis virus: Characterization of a mutated chicken syncytial virus provirus involved in c-myc activation Journal of Virology. 61: 2084-2090. PMID 3035210 DOI: 10.1128/Jvi.61.7.2084-2090.1987 |
0.336 |
|
| 1986 |
Goodwin RG, Rottman FM, Callaghan T, Kung HJ, Maroney PA, Nilsen TW. c-erbB activation in avian leukosis virus-induced erythroblastosis: multiple epidermal growth factor receptor mRNAs are generated by alternative RNA processing. Molecular and Cellular Biology. 6: 3128-33. PMID 3023963 DOI: 10.1128/mcb.6.9.3128-3133.1986 |
0.315 |
|
| 1986 |
Beug H, Hayman MJ, Raines MB, Kung HJ, Vennström B. Rous-associated virus 1-induced erythroleukemic cells exhibit a weakly transformed phenotype in vitro and release c-erbB-containing retroviruses unable to transform fibroblasts Journal of Virology. 57: 1127-1138. PMID 3005614 DOI: 10.1128/Jvi.57.3.1127-1138.1986 |
0.373 |
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| 1986 |
Isfort RJ, Stringer RA, Kung H, Velicer LF. Synthesis, processing, and secretion of the Marek's disease herpesvirus A antigen glycoprotein. Journal of Virology. 57: 464-474. PMID 3003379 DOI: 10.1128/Jvi.57.2.464-474.1986 |
0.317 |
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| 1985 |
Chang CC, Trosko JE, Kung HJ, Bombick D, Matsumura F. Potential role of the src gene product in inhibition of gap-junctional communication in NIH/3T3 cells. Proceedings of the National Academy of Sciences of the United States of America. 82: 5360-4. PMID 2991919 DOI: 10.1073/Pnas.82.16.5360 |
0.35 |
|
| 1985 |
Swift RA, Shaller E, Witter RL, Kung H. Insertional activation of c-myc by reticuloendotheliosis virus in chicken B lymphoma: nonrandom distribution and orientation of the proviruses. Journal of Virology. 54: 869-872. PMID 2987538 DOI: 10.1128/Jvi.54.3.869-872.1985 |
0.314 |
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| 1985 |
Raines MA, Lewis WG, Crittenden LB, Kung H. c-erbB activation in avian leukosis virus-induced erythroblastosis: clustered integration sites and the arrangement of provirus in the c-erbB alleles. Proceedings of the National Academy of Sciences of the United States of America. 82: 2287-2291. PMID 2986110 DOI: 10.1073/Pnas.82.8.2287 |
0.334 |
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| 1985 |
Ridgway AA, Swift RA, Kung H, Fujita DJ. In vitro transcription analysis of the viral promoter involved in c-myc activation in chicken B lymphomas: detection and mapping of two RNA initiation sites within the reticuloendotheliosis virus long terminal repeat. Journal of Virology. 54: 161-170. PMID 2983111 DOI: 10.1128/Jvi.54.1.161-170.1985 |
0.319 |
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| 1985 |
Gibbs CP, Tanaka A, Anderson SK, Radul J, Baar J, Ridgway A, Kung H, Fujita DJ. Isolation and structural mapping of a human c-src gene homologous to the transforming gene (v-src) of Rous sarcoma virus. Journal of Virology. 53: 19-24. PMID 2981336 DOI: 10.1128/Jvi.53.1.19-24.1985 |
0.313 |
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| 1985 |
Anderson SK, Gibbs CP, Tanaka A, Kung H, Fujita DJ. Human cellular src gene: nucleotide sequence and derived amino acid sequence of the region coding for the carboxy-terminal two-thirds of pp60c-src. Molecular and Cellular Biology. 5: 1122-1129. PMID 2582238 DOI: 10.1128/mcb.5.5.1122-1129.1985 |
0.32 |
|
| 1983 |
Fung YKT, Crittenden LB, Fadly AM, Kung H. Tumor induction by direct injection of cloned v-src DNA into chickens. Proceedings of the National Academy of Sciences of the United States of America. 80: 353-357. PMID 6300833 DOI: 10.1073/Pnas.80.2.353 |
0.309 |
|
| 1982 |
Fung YKT, Crittenden LB, Kung H. Orientation and position of avian leukosis virus DNA relative to the cellular oncogene c-myc in B-lymphoma tumors of highly susceptible 15I5 X 7(2) chickens. Journal of Virology. 44: 742-746. PMID 6292531 DOI: 10.1128/Jvi.44.2.742-746.1982 |
0.325 |
|
| 1982 |
Nazerian K, Witter RL, Crittenden LB, Noori-Dalloii MR, Kung H. An IgM-producing B lymphoblastoid cell line established from lymphomas induced by a non-defective reticuloendotheliosis virus Journal of General Virology. 58: 351-360. PMID 6278061 DOI: 10.1099/0022-1317-58-2-351 |
0.331 |
|
| 1981 |
Kung H, Fung YK, Crittenden LC, Fadly A, Dube SK. The molecular basis of avian retrovirus-induced leukemogenesis. Haematology and Blood Transfusion. 26: 445-451. PMID 6274758 DOI: 10.1007/978-3-642-67984-1_81 |
0.325 |
|
| 1981 |
Fung YT, Fadly AM, Crittenden LB, Kung H. On the mechanism of retrovirus-induced avian lymphoid leukosis: deletion and integration of the proviruses Proceedings of the National Academy of Sciences of the United States of America. 78: 3418-3422. PMID 6267589 DOI: 10.1073/Pnas.78.6.3418 |
0.321 |
|
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