| Year |
Citation |
Score |
| 2019 |
Pacchierotti F, Masumura K, Eastmond DA, Elhajouji A, Froetschl R, Kirsch-Volders M, Lynch A, Schuler M, Tweats D, Marchetti F. Chemically induced aneuploidy in germ cells. Part II of the report of the 2017 IWGT workgroup on assessing the risk of aneugens for carcinogenesis and hereditary diseases. Mutation Research. 848: 403023. PMID 31708072 DOI: 10.1016/j.mrgentox.2019.02.004 |
0.358 |
|
| 2019 |
Lynch AM, Eastmond D, Elhajouji A, Froetschl R, Kirsch-Volders M, Marchetti F, Masumura K, Pacchierotti F, Schuler M, Tweats D. Targets and mechanisms of chemically induced aneuploidy. Part 1 of the report of the 2017 IWGT workgroup on assessing the risk of aneugens for carcinogenesis and hereditary diseases. Mutation Research. 847: 403025. PMID 31699346 DOI: 10.1016/J.Mrgentox.2019.02.006 |
0.359 |
|
| 2019 |
Gollapudi P, Bhat VS, Eastmond DA. Concentration-response studies of the chromosome-damaging effects of topoisomerase II inhibitors determined in vitro using human TK6 cells. Mutation Research. 841: 49-56. PMID 31138411 DOI: 10.1016/j.mrgentox.2019.05.006 |
0.49 |
|
| 2016 |
Balakrishnan S, Hasegawa L, Eastmond DA. The role of urinary pH in o-phenylphenol-induced cytotoxicity and chromosomal damage in the bladders of F344 rats. Environmental and Molecular Mutagenesis. 57: 210-9. PMID 26919225 DOI: 10.1002/em.22002 |
0.531 |
|
| 2015 |
Sankaran G, Chen L, Chen Z, Liu Y, Lopez T, Ross J, Phagura S, Eastmond DA, Krieger RI. The Importance of Hand Exposures to Absorbed Dosage of Hand Harvesters. Journal of Toxicology and Environmental Health. Part A. 78: 1369-83. PMID 26580450 DOI: 10.1080/15287394.2015.1092900 |
0.587 |
|
| 2015 |
Sankaran G, Lopez T, Ries S, Ross J, Vega H, Eastmond DA, Krieger RI. Latex Rubber Gloves as a Sampling Dosimeter Using a Novel Surrogate Sampling Device. Journal of Toxicology and Environmental Health. Part A. 78: 1094-104. PMID 26302432 DOI: 10.1080/15287394.2015.1037411 |
0.575 |
|
| 2015 |
Hester S, Eastmond DA, Bhat VS. Developing toxicogenomics as a research tool by applying benchmark dose-response modelling to inform chemical mode of action and tumorigenic potency International Journal of Biotechnology. 14: 28-46. DOI: 10.1504/IJBT.2015.074796 |
0.563 |
|
| 2014 |
Gollapudi P, Hasegawa LS, Eastmond DA. A comparative study of the aneugenic and polyploidy-inducing effects of fisetin and two model Aurora kinase inhibitors Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 767: 37-43. PMID 24680981 DOI: 10.1016/j.mrgentox.2014.03.004 |
0.354 |
|
| 2013 |
Bhat VS, Hester SD, Nesnow S, Eastmond DA. Concordance of transcriptional and apical benchmark dose levels for conazole-induced liver effects in mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 136: 205-15. PMID 23970803 DOI: 10.1093/Toxsci/Kft182 |
0.577 |
|
| 2013 |
Vuong MC, Hasegawa LS, Eastmond DA. A comparative study of the cytotoxic and genotoxic effects of ICRF-154 and bimolane, two catalytic inhibitors of topoisomerase II. Mutation Research. 750: 63-71. PMID 23000430 DOI: 10.1016/j.mrgentox.2012.09.005 |
0.432 |
|
| 2011 |
Roy SK, Eastmond DA. Bimolane induces multiple types of chromosomal aberrations in human lymphocytes in vitro. Mutation Research. 726: 181-7. PMID 21944901 DOI: 10.1016/j.mrgentox.2011.09.006 |
0.423 |
|
| 2011 |
Galloway S, Lorge E, Aardema MJ, Eastmond D, Fellows M, Heflich R, Kirkland D, Levy DD, Lynch AM, Marzin D, Morita T, Schuler M, Speit G. Workshop summary: Top concentration for in vitro mammalian cell genotoxicity assays; and report from working group on toxicity measures and top concentration for in vitro cytogenetics assays (chromosome aberrations and micronucleus). Mutation Research. 723: 77-83. PMID 21255675 DOI: 10.1016/J.Mrgentox.2011.01.003 |
0.432 |
|
| 2011 |
Fenech M, Kirsch-Volders M, Natarajan AT, Surralles J, Crott JW, Parry J, Norppa H, Eastmond DA, Tucker JD, Thomas P. Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells Mutagenesis. 26: 125-132. PMID 21164193 DOI: 10.1093/Mutage/Geq052 |
0.357 |
|
| 2010 |
Mondrala S, Eastmond DA. Topoisomerase II inhibition by the bioactivated benzene metabolite hydroquinone involves multiple mechanisms. Chemico-Biological Interactions. 184: 259-68. PMID 20034485 DOI: 10.1016/J.Cbi.2009.12.023 |
0.712 |
|
| 2009 |
Pfuhler S, Kirkland D, Kasper P, Hayashi M, Vanparys P, Carmichael P, Dertinger S, Eastmond D, Elhajouji A, Krul C, Rothfuss A, Schoening G, Smith A, Speit G, Thomas C, et al. Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities-Report from an ECVAM workshop. Mutation Research. 680: 31-42. PMID 19765670 DOI: 10.1016/J.Mrgentox.2009.09.002 |
0.372 |
|
| 2007 |
Wang L, Roy SK, Eastmond DA. Differential cell cycle-specificity for chromosomal damage induced by merbarone and etoposide in V79 cells. Mutation Research. 616: 70-82. PMID 17174356 DOI: 10.1016/j.mrfmmm.2006.11.023 |
0.403 |
|
| 2007 |
Ramírez T, Eastmond DA, Herrera LA. Non-disjunction events induced by albendazole in human cells. Mutation Research. 626: 191-5. PMID 17055335 DOI: 10.1016/j.mrgentox.2006.09.004 |
0.415 |
|
| 2006 |
Balakrishnan S, Eastmond DA. Micronuclei and cell proliferation as early biological markers of ortho-phenylphenol-induced changes in the bladder of male F344 rats. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 44: 1340-7. PMID 16621212 DOI: 10.1016/j.fct.2006.02.011 |
0.527 |
|
| 2006 |
Olaharski AJ, Sotelo R, Solorza-Luna G, Gonsebatt ME, Guzman P, Mohar A, Eastmond DA. Tetraploidy and chromosomal instability are early events during cervical carcinogenesis. Carcinogenesis. 27: 337-43. PMID 16123119 DOI: 10.1093/Carcin/Bgi218 |
0.748 |
|
| 2005 |
Eastmond DA, Mondrala ST, Hasegawa L. Topoisomerase II inhibition by myeloperoxidase-activated hydroquinone: a potential mechanism underlying the genotoxic and carcinogenic effects of benzene. Chemico-Biological Interactions. 153: 207-16. PMID 15935818 DOI: 10.1016/J.Cbi.2005.03.024 |
0.715 |
|
| 2005 |
Uppala PT, Roy SK, Tousson A, Barnes S, Uppala GR, Eastmond DA. Induction of cell proliferation, micronuclei and hyperdiploidy/polyploidy in the mammary cells of DDT- and DMBA-treated pubertal rats. Environmental and Molecular Mutagenesis. 46: 43-52. PMID 15880734 DOI: 10.1002/em.20131 |
0.327 |
|
| 2005 |
Olaharski AJ, Mondrala ST, Eastmond DA. Chromosomal malsegregation and micronucleus induction in vitro by the DNA topoisomerase II inhibitor fisetin. Mutation Research. 582: 79-86. PMID 15781213 DOI: 10.1016/J.Mrgentox.2005.01.002 |
0.661 |
|
| 2004 |
Olaharski AJ, Eastmond DA. Elevated levels of tetraploid cervical cells in human papillomavirus-positive Papanicolaou smears diagnosed as atypical squamous cells of undetermined significance. Cancer. 102: 192-9. PMID 15211479 DOI: 10.1002/Cncr.20259 |
0.697 |
|
| 2003 |
Balakrishnan S, Eastmond DA. Evaluation of hyperdiploidy in the bladder epithelial cells of male F344 rats treated with ortho-phenylphenol. Mutation Research. 537: 11-20. PMID 12742503 DOI: 10.1016/S1383-5718(03)00047-0 |
0.596 |
|
| 2003 |
Schuler M, Muehlbauer P, Guzzie P, Eastmond DA. Noscapine hydrochloride-induced numerical aberrations in cultured human lymphocytes: A comparison of FISH detection methods and multiple end-points Mutagenesis. 18: 235-242. PMID 12714688 DOI: 10.1093/mutage/18.3.235 |
0.422 |
|
| 2002 |
Balakrishnan S, Payawal J, Schuler MJ, Hasegawa L, Eastmond DA. Enhancing the in vitro and in vivo detection of aneuploidy by fluorescence in situ hybridization with the use of bromodeoxyuridine as a proliferation marker. Mutation Research. 521: 81-9. PMID 12438006 DOI: 10.1016/S1383-5718(02)00220-6 |
0.568 |
|
| 2002 |
Wang L, Eastmond DA. Catalytic inhibitors of topoisomerase II are DNA-damaging agents: induction of chromosomal damage by merbarone and ICRF-187. Environmental and Molecular Mutagenesis. 39: 348-56. PMID 12112387 DOI: 10.1002/em.10072 |
0.423 |
|
| 2002 |
Zhang L, Eastmond DA, Smith MT. The nature of chromosomal aberrations detected in humans exposed to benzene. Critical Reviews in Toxicology. 32: 1-42. PMID 11846214 DOI: 10.1080/20024091064165 |
0.384 |
|
| 2002 |
Balakrishnan S, Uppala PT, Rupa DS, Hasegawa L, Eastmond DA. Detection of micronuclei, cell proliferation and hyperdiploidy in bladder epithelial cells of rats treated with o-phenylphenol. Mutagenesis. 17: 89-93. PMID 11752240 |
0.571 |
|
| 2001 |
Eastmond DA, Schuler M, Frantz C, Chen H, Parks R, Wang L, Hasegawa L. Characterization and mechanisms of chromosomal alterations induced by benzene in mice and humans Research Report (Health Effects Institute). PMID 11504146 |
0.47 |
|
| 1999 |
Murg MN, Schuler M, Eastmond DA. Persistence of chromosomal alterations affecting the 1cen-q12 region in a human lymphoblastoid cell line exposed to diepoxybutane and mitomycin C Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 446: 193-203. PMID 10635342 DOI: 10.1016/S1383-5718(99)00184-9 |
0.358 |
|
| 1999 |
Marcon F, Zijno A, Crebelli R, Carere A, Veidebaum T, Peltonen K, Parks R, Schuler M, Eastmond D. Chromosome damage and aneuploidy detected by interphase multicolour FISH in benzene-exposed shale oil workers. Mutation Research. 445: 155-66. PMID 10575426 DOI: 10.1016/S1383-5718(99)00122-9 |
0.447 |
|
| 1999 |
Murg MN, Schuler M, Eastmond DA. Evaluation of micronuclei and chromosomal breakage in the 1cen-q12 region by the butadiene metabolites epoxybutene and diepoxybutane in cultured human lymphocytes Mutagenesis. 14: 541-546. PMID 10567028 |
0.403 |
|
| 1999 |
Schuler M, Muehlbauer P, Guzzie P, Eastmond DA. Noscapine hydrochloride disrupts the mitotic spindle in mammalian cells and induces aneuploidy as well as polyploidy in cultured human lymphocytes Mutagenesis. 14: 51-56. PMID 10474821 DOI: 10.1093/mutage/14.1.51 |
0.431 |
|
| 1998 |
Smith LE, Parks KK, Hasegawa LS, Eastmond DA, Grosovsky AJ. Targeted breakage of paracentromeric heterochromatin induces chromosomal instability Mutagenesis. 13: 435-443. PMID 9800188 DOI: 10.1093/Mutage/13.5.435 |
0.367 |
|
| 1998 |
Schuler M, Hasegawa L, Parks R, Metzler M, Eastmond DA. Dose-response studies of the induction of hyperdiploidy and polyploidy by diethylstilbestrol and 17β-estradiol in cultured human lymphocytes using multicolor fluorescence in situ hybridization Environmental and Molecular Mutagenesis. 31: 263-273. PMID 9585265 DOI: 10.1002/(SICI)1098-2280(1998)31:3<263::AID-EM8>3.0.CO;2-L |
0.366 |
|
| 1997 |
Frantz CE, Smith H, Eades DM, Grosovsky AJ, Eastmond DA. Bimolane: In vitro inhibitor of human topoisomerase II Cancer Letters. 120: 135-140. PMID 9461029 DOI: 10.1016/S0304-3835(97)00303-0 |
0.403 |
|
| 1997 |
Rupa DS, Eastmond DA. Chromosomal alterations affecting the 1cen-1q12 region in buccal mucosal cells of betel quid chewers detected using multicolor fluorescence in situ hybridization Carcinogenesis. 18: 2347-2351. PMID 9450480 DOI: 10.1093/carcin/18.12.2347 |
0.373 |
|
| 1997 |
Schuler M, Rupa DS, Eastmond DA. A critical evaluation of centromeric labeling to distinguish micronuclei induced by chromosomal loss and breakage in vitro Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 392: 81-95. PMID 9269333 DOI: 10.1016/S0165-1218(97)00047-5 |
0.37 |
|
| 1997 |
Rupa DS, Hasegawa LS, Eastmond DA. Detection of chromosomal alterations affecting the 1cen-1q12 region in irradiated granulocytes and lymphocytes by multicolour FISH with tandem DNA probes Mutagenesis. 12: 195-200. PMID 9237761 DOI: 10.1093/mutage/12.4.195 |
0.324 |
|
| 1997 |
Dopp E, Schuler M, Schiffmann D, Eastmond DA. Induction of micronuclei, hyperdiploidy and chromosomal breakage affecting the centric/pericentric regions of chromosomes 1 and 9 in human amniotic fluid cells after treatment with asbestos and ceramic fibers Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 377: 77-87. PMID 9219582 DOI: 10.1016/S0027-5107(97)00062-6 |
0.323 |
|
| 1997 |
Ramírez P, Eastmond DA, Laclette JP, Ostrosky-Wegman P. Disruption of microtubule assembly and spindle formation as a mechanism for the induction of aneuploid cells by sodium arsenite and vanadium pentoxide Mutation Research - Reviews in Mutation Research. 386: 291-298. PMID 9219566 DOI: 10.1016/S1383-5742(97)00018-5 |
0.356 |
|
| 1997 |
Rupa DS, Schuler M, Eastmond DA. Detection of hyperdiploidy and breakage affecting the 1cen-1q12 region of cultured interphase human lymphocytes treated with various genotoxic agents Environmental and Molecular Mutagenesis. 29: 161-167. PMID 9118968 DOI: 10.1002/(SICI)1098-2280(1997)29:2<161::AID-EM7>3.0.CO;2-H |
0.381 |
|
| 1996 |
Frantz CE, Chen H, Eastmond DA. Inhibition of human topoisomerase II in vitro by bioactive benzene metabolites Environmental Health Perspectives. 104: 1319-1323. PMID 9118913 |
0.402 |
|
| 1995 |
Hasegawa LS, Rupa DS, Eastmond DA. A method for the rapid generation of alpha-and classical satellite probes for human chromosome 9 by polymerase chain reaction using genomic DNA and their application to detect chromosomal alterations in interphase cells Mutagenesis. 10: 471-476. PMID 8596465 DOI: 10.1093/mutage/10.6.471 |
0.386 |
|
| 1995 |
Rupa DS, Hasegawa L, Eastmond DA. Detection of Chromosomal Breakage in the 1cen-1q12 Region of Interphase Human Lymphocytes Using Multicolor Fluorescence in Situ Hybridization with Tandem DNA Probes Cancer Research. 55: 640-645. PMID 7834635 |
0.354 |
|
| 1995 |
Chen H, Eastmond DA. Topoisomerase inhibition by phenolic metabolites: A potential mechanism for benzene's clastogenic effects Carcinogenesis. 16: 2301-2307. PMID 7586126 DOI: 10.1093/carcin/16.10.2301 |
0.487 |
|
| 1994 |
Chen H, Rupa DS, Tomar R, Eastmond DA. Chromosomal Loss and Breakage in Mouse Bone Marrow and Spleen Cells Exposed to Benzene in Vivo Cancer Research. 54: 3533-3539. PMID 8012977 |
0.359 |
|
| 1994 |
Dobo KL, Eastmond DA. Role of oxygen radicals in the chromosomal loss and breakage induced by the quinone‐forming compounds, hydroquinone and tert‐butylhydroquinone Environmental and Molecular Mutagenesis. 24: 293-300. PMID 7851341 DOI: 10.1002/em.2850240406 |
0.403 |
|
| 1994 |
Chen HW, Tomar R, Eastmond DA. Detection of hydroquinone-induced nonrandom breakage in the centromeric heterochromatin of mouse bone marrow cells using multicolor fluorescence in situ hybridization with the mouse major and minor satellite probes Mutagenesis. 9: 563-569. PMID 7531808 DOI: 10.1093/mutage/9.6.563 |
0.331 |
|
| 1994 |
Eastmond DA, Rupa DS, Hasegawa LS. Detection of hyperdiploidy and chromosome breakage in interphase human lymphocytes following exposure to the benzene metabolite hydroquinone using multicolor fluorescence in situ hybridization with DNA probes Mutation Research/Genetic Toxicology. 322: 9-20. PMID 7517507 DOI: 10.1016/0165-1218(94)90028-0 |
0.37 |
|
| 1993 |
Eastmond DA. Induction of micronuclei and aneuploidy by the quinone-forming agents benzene and o-phenylphenol Toxicology Letters. 67: 105-118. PMID 8451753 DOI: 10.1016/0378-4274(93)90049-4 |
0.325 |
|
| 1991 |
Robertson ML, Eastmond DA, Smith MT. Two benzene metabolites, catechol and hydroquinone, produce a synergistic induction of micronuclei and toxicity in cultured human lymphocytes. Mutation Research. 249: 201-9. PMID 2067533 DOI: 10.1016/0027-5107(91)90147-G |
0.375 |
|
| 1990 |
Yager JW, Eastmond DA, Robertson ML, Paradisin WM, Smith MT. Characterization of micronuclei induced in human lymphocytes by benzene metabolites. Cancer Research. 50: 393-9. PMID 2295079 |
0.419 |
|
| 1990 |
Eastmond DA, Pinkel D. Detection of aneuploidy and aneuploidy-inducing agents in human lymphocytes using fluorescence in situ hybridization with chromosome-specific DNA probes Mutation Research/Environmental Mutagenesis and Related Subjects. 234: 303-318. PMID 2215545 DOI: 10.1016/0165-1161(90)90041-L |
0.365 |
|
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