Mary L. Michaelis - Publications

Affiliations: 
University of Kansas, Lawrence, KS, United States 
Area:
Pharmacology, Toxicology, Neuroscience Biology

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Pal R, Hui D, Menchen H, Zhao H, Mozziconacci O, Wilkins H, Blagg BSJ, Schöneich C, Swerdlow RH, Michaelis ML, Michaelis EK. Protection against Aβ-induced neuronal damage by KU-32: PDHK1 inhibition as important target. Frontiers in Aging Neuroscience. 15: 1282855. PMID 38035268 DOI: 10.3389/fnagi.2023.1282855  0.717
2019 Agbas A, Krishnamurthy P, Michaelis ML, Michaelis EK. Mitochondrial Electron Transfer Cascade Enzyme Activity Assessment in Cultured Neurons and Select Brain Regions. Current Protocols in Toxicology. e73. PMID 30951613 DOI: 10.1002/Cptx.73  0.357
2016 Wilkins HM, Koppel S, Carl SM, Ramanujan S, Weidling I, Michaelis ML, Michaelis EK, Swerdlow RH. Oxaloacetate Enhances Neuronal Cell Bioenergetic Fluxes and Infrastructure. Journal of Neurochemistry. PMID 26811028 DOI: 10.1111/Jnc.13545  0.314
2014 Wilkins HM, Harris JL, Carl SM, E L, Lu J, Eva Selfridge J, Roy N, Hutfles L, Koppel S, Morris J, Burns JM, Michaelis ML, Michaelis EK, Brooks WM, Swerdlow RH. Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis. Human Molecular Genetics. 23: 6528-41. PMID 25027327 DOI: 10.1093/Hmg/Ddu371  0.355
2014 Jiang L, Bechtel MD, Bean JL, Winefield R, Williams TD, Zaidi A, Michaelis EK, Michaelis ML. Effects of gangliosides on the activity of the plasma membrane Ca2+-ATPase. Biochimica Et Biophysica Acta. 1838: 1255-65. PMID 24434060 DOI: 10.1016/J.Bbamem.2014.01.003  0.395
2012 Jiang L, Bechtel MD, Galeva NA, Williams TD, Michaelis EK, Michaelis ML. Decreases in plasma membrane Ca²⁺-ATPase in brain synaptic membrane rafts from aged rats. Journal of Neurochemistry. 123: 689-99. PMID 22889001 DOI: 10.1111/J.1471-4159.2012.07918.X  0.351
2012 Zhao H, Michaelis ML, Blagg BS. Hsp90 modulation for the treatment of Alzheimer's disease. Advances in Pharmacology (San Diego, Calif.). 64: 1-25. PMID 22840743 DOI: 10.1016/B978-0-12-394816-8.00001-5  0.321
2011 Hascup KN, Bao X, Hascup ER, Hui D, Xu W, Pomerleau F, Huettl P, Michaelis ML, Michaelis EK, Gerhardt GA. Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum. Asn Neuro. 3. PMID 21446915 DOI: 10.1042/An20110005  0.341
2011 Kim J, Choi IY, Michaelis ML, Lee P. Quantitative in vivo measurement of early axonal transport deficits in a triple transgenic mouse model of Alzheimer's disease using manganese-enhanced MRI. Neuroimage. 56: 1286-92. PMID 21338698 DOI: 10.1016/J.Neuroimage.2011.02.039  0.308
2010 Wang X, Michaelis ML, Michaelis EK. Functional genomics of brain aging and Alzheimer's disease: focus on selective neuronal vulnerability. Current Genomics. 11: 618-33. PMID 21629439 DOI: 10.2174/138920210793360943  0.379
2010 Jiang L, Fang J, Moore DS, Gogichaeva NV, Galeva NA, Michaelis ML, Zaidi A. Age-associated changes in synaptic lipid raft proteins revealed by two-dimensional fluorescence difference gel electrophoresis. Neurobiology of Aging. 31: 2146-59. PMID 19118924 DOI: 10.1016/J.Neurobiolaging.2008.11.005  0.337
2009 Bao X, Pal R, Hascup KN, Wang Y, Wang WT, Xu W, Hui D, Agbas A, Wang X, Michaelis ML, Choi IY, Belousov AB, Gerhardt GA, Michaelis EK. Transgenic expression of Glud1 (glutamate dehydrogenase 1) in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 13929-44. PMID 19890003 DOI: 10.1523/Jneurosci.4413-09.2009  0.418
2009 Desino KE, Ansar S, Georg GI, Himes RH, Michaelis ML, Powell DR, Reiff EA, Telikepalli H, Audus KL. (3R,5S,7as)-(3,5-Bis(4-fluorophenyl)tetrahydro-1H-oxazolo[3,4-c]oxazol-7a-yl)methanol, a novel neuroprotective agent. Journal of Medicinal Chemistry. 52: 7537-43. PMID 19728715 DOI: 10.1021/Jm900254K  0.304
2009 Zaidi A, Fernandes D, Bean JL, Michaelis ML. Effects of paraquat-induced oxidative stress on the neuronal plasma membrane Ca(2+)-ATPase. Free Radical Biology & Medicine. 47: 1507-14. PMID 19715754 DOI: 10.1016/J.Freeradbiomed.2009.08.018  0.433
2009 Desino KE, Pignatello R, Guccione S, Basile L, Ansar S, Michaelis ML, Ramsay RR, Audus KL. TCP-FA4: a derivative of tranylcypromine showing improved blood-brain permeability. Biochemical Pharmacology. 78: 1412-7. PMID 19679106 DOI: 10.1016/J.Bcp.2009.07.027  0.305
2009 Wang X, Zaidi A, Pal R, Garrett AS, Braceras R, Chen XW, Michaelis ML, Michaelis EK. Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress. Bmc Neuroscience. 10: 12. PMID 19228403 DOI: 10.1186/1471-2202-10-12  0.427
2009 Lu Y, Ansar S, Michaelis ML, Blagg BS. Neuroprotective activity and evaluation of Hsp90 inhibitors in an immortalized neuronal cell line. Bioorganic & Medicinal Chemistry. 17: 1709-15. PMID 19138859 DOI: 10.1016/J.Bmc.2008.12.047  0.498
2009 Michaelis ML, Georg G, Telikepalli H, McIntosh M, Rajewski RA. Ongoing in vivo studies with cytoskeletal drugs in tau transgenic mice (Current Alzheimer Research 3, 3, (215-219)) Current Alzheimer Research. 6: 320. DOI: 10.2174/156720509788486635  0.323
2008 Seyb KI, Schuman ER, Ni J, Huang MM, Michaelis ML, Glicksman MA. Identification of small molecule inhibitors of beta-amyloid cytotoxicity through a cell-based high-throughput screening platform. Journal of Biomolecular Screening. 13: 870-8. PMID 18812568 DOI: 10.1177/1087057108323909  0.737
2008 Michaelis EK, Bao X, Pal R, Hascup K, McKerchar T, Xu W, Hui D, Agbas A, Wang X, Pinkston J, Pomerleau F, Huettl P, Fowler S, Michaelis M, Gerhardt G. P4-259: Transgenic expression of glutamate gehydrogenase 1 in neurons: An in vivo model of hyperglutamatergic nervous system and chronic neurodegeneration Alzheimer's & Dementia. 4: T747-T747. DOI: 10.1016/J.Jalz.2008.05.2328  0.368
2008 Michaelis ML, Ansar S, Chigurupati R, Menchen H, Blagg B, Rajewski R. P2-384: In vivo effects of novel Hsp90 C-terminal inhibitors in Tau mutant mice Alzheimer's & Dementia. 4: T485-T485. DOI: 10.1016/J.Jalz.2008.05.1462  0.674
2007 Jiang L, Fernandes D, Mehta N, Bean JL, Michaelis ML, Zaidi A. Partitioning of the plasma membrane Ca2+-ATPase into lipid rafts in primary neurons: effects of cholesterol depletion. Journal of Neurochemistry. 102: 378-88. PMID 17596212 DOI: 10.1111/J.1471-4159.2007.04480.X  0.372
2007 Fernandes D, Zaidi A, Bean J, Hui D, Michaelis ML. RNA--induced silencing of the plasma membrane Ca2+-ATPase 2 in neuronal cells: effects on Ca2+ homeostasis and cell viability. Journal of Neurochemistry. 102: 454-65. PMID 17488275 DOI: 10.1111/J.1471-4159.2007.04592.X  0.388
2007 Seyb KI, Ansar S, Li G, Bean J, Michaelis ML, Dobrowsky RT. p35/Cyclin-dependent kinase 5 is required for protection against beta-amyloid-induced cell death but not tau phosphorylation by ceramide. Journal of Molecular Neuroscience : Mn. 31: 23-35. PMID 17416967 DOI: 10.1007/Bf02686115  0.766
2007 Butler D, Bendiske J, Michaelis ML, Karanian DA, Bahr BA. Microtubule-stabilizing agent prevents protein accumulation-induced loss of synaptic markers. European Journal of Pharmacology. 562: 20-7. PMID 17336290 DOI: 10.1016/J.Ejphar.2007.01.053  0.373
2007 Ansar S, Burlison JA, Hadden MK, Yu XM, Desino KE, Bean J, Neckers L, Audus KL, Michaelis ML, Blagg BS. A non-toxic Hsp90 inhibitor protects neurons from Abeta-induced toxicity. Bioorganic & Medicinal Chemistry Letters. 17: 1984-90. PMID 17276679 DOI: 10.1016/J.Bmcl.2007.01.017  0.445
2006 Michaelis ML, Georg G, Telikepalli H, McIntosh M, Rajewski RA. Ongoing in vivo studies with cytoskeletal drugs in tau transgenic mice. Current Alzheimer Research. 3: 215-9. PMID 16842098 DOI: 10.2174/156720506777632880  0.393
2006 Seyb KI, Ansar S, Bean J, Michaelis ML. beta-Amyloid and endoplasmic reticulum stress responses in primary neurons: effects of drugs that interact with the cytoskeleton. Journal of Molecular Neuroscience : Mn. 28: 111-23. PMID 16679552 DOI: 10.1385/Jmn:28:2:111  0.78
2006 Michaelis EK, Pal R, Schoneich C, Wilkins HM, Swerdlow RH, Michaelis ML. P1-225: PROTECTION AGAINST AB-INDUCED NEURONAL DAMAGE BY AN HSP90 C-TERMINAL MODULATOR: IMPORTANCE OF PYRUVATE DEHYDROGENASE KINASE Alzheimer's & Dementia. 14: P364-P365. DOI: 10.1016/J.Jalz.2018.06.230  0.423
2005 Lushington GH, Zaidi A, Michaelis ML. Theoretically predicted structures of plasma membrane Ca(2+)-ATPase and their susceptibilities to oxidation. Journal of Molecular Graphics & Modelling. 24: 175-85. PMID 16169758 DOI: 10.1016/J.Jmgm.2005.07.003  0.333
2005 Michaelis ML, Seyb KI, Ansar S. Cytoskeletal integrity as a drug target. Current Alzheimer Research. 2: 227-9. PMID 15974922 DOI: 10.2174/1567205053585837  0.766
2005 Rice A, Liu Y, Michaelis ML, Himes RH, Georg GI, Audus KL. Chemical modification of paclitaxel (Taxol) reduces P-glycoprotein interactions and increases permeation across the blood-brain barrier in vitro and in situ. Journal of Medicinal Chemistry. 48: 832-8. PMID 15689167 DOI: 10.1021/Jm040114B  0.323
2005 Michaelis ML, Ansar S, Chen Y, Reiff ER, Seyb KI, Himes RH, Audus KL, Georg GI. {beta}-Amyloid-induced neurodegeneration and protection by structurally diverse microtubule-stabilizing agents. The Journal of Pharmacology and Experimental Therapeutics. 312: 659-68. PMID 15375176 DOI: 10.1124/Jpet.104.074450  0.785
2004 Michaelis ML, Seyb KI, Ansar S, Bean JL, Georg G. P3-192 Parallels between ER-stress and Aβ-induced toxicity in primary neurons: involvement of the cytoskeletal network Neurobiology of Aging. 25: S410. DOI: 10.1016/S0197-4580(04)81344-7  0.754
2003 Pal R, Agbas A, Bao X, Hui D, Leary C, Hunt J, Naniwadekar A, Michaelis ML, Kumar KN, Michaelis EK. Selective dendrite-targeting of mRNAs of NR1 splice variants without exon 5: identification of a cis-acting sequence and isolation of sequence-binding proteins. Brain Research. 994: 1-18. PMID 14642443 DOI: 10.1016/J.Brainres.2003.08.046  0.314
2003 Rice A, Michaelis ML, Georg G, Liu Y, Turunen B, Audus KL. Overcoming the blood-brain barrier to taxane delivery for neurodegenerative diseases and brain tumors. Journal of Molecular Neuroscience : Mn. 20: 339-43. PMID 14501017 DOI: 10.1385/Jmn:20:3:339  0.329
2003 Michaelis ML. Drugs targeting Alzheimer's disease: some things old and some things new. The Journal of Pharmacology and Experimental Therapeutics. 304: 897-904. PMID 12604663 DOI: 10.1124/Jpet.102.035840  0.409
2003 Li G, Faibushevich A, Turunen BJ, Yoon SO, Georg G, Michaelis ML, Dobrowsky RT. Stabilization of the cyclin-dependent kinase 5 activator, p35, by paclitaxel decreases beta-amyloid toxicity in cortical neurons. Journal of Neurochemistry. 84: 347-62. PMID 12558997 DOI: 10.1046/J.1471-4159.2003.01526.X  0.487
2002 Michaelis ML, Dobrowsky RT, Li G. Tau neurofibrillary pathology and microtubule stability. Journal of Molecular Neuroscience : Mn. 19: 289-93. PMID 12540054 DOI: 10.1385/Jmn:19:3:289  0.483
2002 Michaelis ML, Chen Y, Hill S, Reiff E, Georg G, Rice A, Audus K. Amyloid peptide toxicity and microtubule-stabilizing drugs. Journal of Molecular Neuroscience : Mn. 19: 101-5. PMID 12212764 DOI: 10.1007/S12031-002-0018-2  0.532
2001 Zaidi A, Cross AM, Bean JL, Michaelis ML. Modification of Synaptic Plasma Membrane Ca2+-ATPase in Ischemic Injury in an Animal Model of Global Ischemia Stroke. 32: 354-354. DOI: 10.1161/01.Str.32.Suppl_1.354-A  0.372
2000 Ranciat-McComb NS, Bland KS, Huschenbett J, Ramonda L, Bechtel M, Zaidi A, Michaelis ML. Antisense oligonucleotide suppression of Na(+)/Ca(2+) exchanger activity in primary neurons from rat brain. Neuroscience Letters. 294: 13-6. PMID 11044575 DOI: 10.1016/S0304-3940(00)01524-X  0.363
1999 Zaidi A, Michaelis ML. Effects of reactive oxygen species on brain synaptic plasma membrane Ca2+-ATPase Free Radical Biology and Medicine. 27: 810-821. PMID 10515585 DOI: 10.1016/S0891-5849(99)00128-8  0.37
1998 Huschenbett J, Zaidi A, Michaelis ML. Sensitivity of the synaptic membrane Na+/Ca2+ exchanger and the expressed NCX1 isoform to reactive oxygen species Biochimica Et Biophysica Acta - Biomembranes. 1374: 34-46. PMID 9814850 DOI: 10.1016/S0005-2736(98)00121-7  0.34
1998 Michaelis ML, Ranciat N, Chen Y, Bechtel M, Ragan R, Hepperle M, Liu Y, Georg G. Protection against beta-amyloid toxicity in primary neurons by paclitaxel (Taxol). Journal of Neurochemistry. 70: 1623-7. PMID 9523579 DOI: 10.1046/J.1471-4159.1998.70041623.X  0.579
1997 Chen X, Michaelis ML, Michaelis EK. Effects of chronic ethanol treatment on the expression of calcium transport carriers and NMDA/glutamate receptor proteins in brain synaptic membranes. Journal of Neurochemistry. 69: 1559-69. PMID 9326285 DOI: 10.1046/J.1471-4159.1997.69041559.X  0.329
1996 Michaelis ML, Bigelow DJ, Schöneich C, Williams TD, Ramonda L, Yin D, Hühmer AFR, Yao Y, Gao J, Squier TC. Decreased plasma membrane calcium transport activity in aging brain Life Sciences. 59: 405-412. PMID 8761328 DOI: 10.1016/0024-3205(96)00319-0  0.307
1996 Michaelis EK, Chen X, Joseph DB, Hurlbert M, Kumar KN, Michaelis ML. Ethanol-induced inhibition of [3H]thienylcyclohexylpiperidine (TCP) binding to NMDA receptors in brain synaptic membranes and to a purified protein complex. Journal of Neurochemistry. 67: 201-11. PMID 8666993 DOI: 10.1046/J.1471-4159.1996.67010201.X  0.321
1996 Bland KS, Takahashi K, Islam S, Michaelis ML. Effects of NCX1 antisense oligodeoxynucleotides on cardiac myocytes and primary neurons in culture. Annals of the New York Academy of Sciences. 779: 119-20. PMID 8659818 DOI: 10.1111/J.1749-6632.1996.Tb44777.X  0.325
1996 Michaelis ML, Huschenbett J. Chapter 6 Neuronal Calcium Regulation in Aging Brain Advances in Cell Aging and Gerontology. 1: 139-155. DOI: 10.1016/S1566-3124(08)60041-3  0.366
1995 Xia Y, Ragan RE, Seah EE, Michaelis ML, Michaelis EK. Developmental expression of N-methyl-D-aspartate (NMDA)-induced neurotoxicity, NMDA receptor function, and the NMDAR1 and glutamate-binding protein subunits in cerebellar granule cells in primary cultures. Neurochemical Research. 20: 617-29. PMID 7643968 DOI: 10.1007/Bf01694545  0.378
1994 Michaelis ML. Ion transport systems and Ca2+ regulation in aging neurons Annals of the New York Academy of Sciences. 747: 407-418. PMID 7847687 DOI: 10.1111/J.1749-6632.1994.Tb44425.X  0.326
1994 Michaelis ML, Walsh JL, Pal R, Hurlbert M, Hoel G, Bland K, Foye J, Kwong WH. Immunologic localization and kinetic characterization of a Na+/Ca2+ exchanger in neuronal and non-neuronal cells Brain Research. 661: 104-116. PMID 7834362 DOI: 10.1016/0006-8993(94)91187-8  0.433
1992 Michaelis ML, Nunley EW, Jayawickreme C, Hurlbert M, Schueler S, Guilly C. Purification of a Synaptic Membrane Na+/Ca2+ Antiporter and Immunoextraction with Antibodies to a 36‐kDa Protein Journal of Neurochemistry. 58: 147-157. PMID 1727427 DOI: 10.1111/J.1471-4159.1992.Tb09290.X  0.316
1992 Michaelis EK, Michaelis ML. Molecular aspects of glutamate receptors and sodium-calcium exchange carriers in mammalian brain: implications for neuronal development and degeneration. Neurochemical Research. 17: 29-34. PMID 1371600 DOI: 10.1007/Bf00966862  0.372
1990 Hoel G, Michaelis ML, Freed WJ, Kleinman JE. Characterization of Na(+)-Ca2+ exchange activity in plasma membrane vesicles from postmortem human brain. Neurochemical Research. 15: 881-7. PMID 1703282 DOI: 10.1007/Bf00965907  0.301
1989 MICHAELIS ML. Ca2+ Handling Systems and Neuronal Aging Annals of the New York Academy of Sciences. 568: 89-94. PMID 2629587 DOI: 10.1111/J.1749-6632.1989.Tb12494.X  0.333
1987 Michaelis ML, Michaelis EK, Nunley EW, Galton N. Effects of chronic alcohol administration on synaptic membrane Na+-Ca2+ exchange activity. Brain Research. 414: 239-44. PMID 3620929 DOI: 10.1016/0006-8993(87)90004-7  0.324
1987 Michaelis E, Roy S, Galton N, Cunningham M, LeCluyse E, Michaelis M. Correlation of glutamate binding activity with glutamate-binding protein immunoreactivity in the brain of control and alcohol-treated rats Neurochemistry International. 11: 209-218. DOI: 10.1016/0197-0186(87)90011-8  0.32
1985 Michaelis ML, Kitos TE, Tehan T. Differential effects of ethanol on two synaptic membrane Ca2+ transport systems Alcohol. 2: 129-132. PMID 4015827 DOI: 10.1016/0741-8329(85)90029-1  0.318
1984 Michaelis EK, Magruder CD, Lampe RA, Galton N, Chang HH, Michaelis ML. Effects of amphipathic drugs on L'[3H]glutamate binding to synaptic membranes and the purified binding protein. Neurochemical Research. 9: 29-44. PMID 6325975 DOI: 10.1007/Bf00967657  0.325
1984 Michaelis ML, Johe K, Kitos TE. Age-dependent alterations in synaptic membrane systems for Ca2+ regulation Mechanisms of Ageing and Development. 25: 215-225. PMID 6144821 DOI: 10.1016/0047-6374(84)90142-8  0.338
1983 Michaelis ML, Michaelis EK, Tehan T. Alcohol effects on synaptic membrane calcium ion fluxes. Pharmacology, Biochemistry, and Behavior. 18: 19-23. PMID 6314374 DOI: 10.1016/0091-3057(83)90141-7  0.311
1983 Michaelis ML, Michaelis EK. Alcohol and local anesthetic effects on Na+-dependent Ca2+ fluxes in brain synaptic membrane vesicles. Biochemical Pharmacology. 32: 963-9. PMID 6301510 DOI: 10.1016/0006-2952(83)90612-3  0.312
1983 Michaelis EK, Michaelis ML, Stormann TM, Chittenden WL, Grubbs RD. Purification and molecular characterization of the brain synaptic membrane glutamate-binding protein. Journal of Neurochemistry. 40: 1742-53. PMID 6133916 DOI: 10.1111/J.1471-4159.1983.Tb08150.X  0.31
1981 Michaelis ML, Michaelis EK. Effects of 2-chloroadenosine on electric potentials in brain synaptic membrane vesicles. Biochimica Et Biophysica Acta. 648: 55-62. PMID 7295731 DOI: 10.1016/0005-2736(81)90123-1  0.306
1981 Michaelis EK, Michaelis ML, Chang HH, Grubbs RD, Kuonen DR. Molecular characteristics of glutamate receptors in the mammalian brain. Molecular and Cellular Biochemistry. 38: 163-79. PMID 6117005 DOI: 10.1007/978-94-009-8027-3_10  0.331
1980 Michaelis EK, Michaelis ML, Belieu RM, Grubbs RD, Magruder C. Effects of in vitro ethanol addition on brain synaptic membrane glutamate binding Brain Research Bulletin. 5: 647-651. DOI: 10.1016/0361-9230(80)90107-0  0.303
1976 Michaelis EK, Michaelis ML. Concanavalin A binding to brain particulate preparations and its effect on adenylate cyclase. Life Sciences. 18: 1021-8. PMID 1271959 DOI: 10.1016/0024-3205(76)90425-2  0.301
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