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Teri A. Manolio, Ph.D. - Publications

Affiliations: 
2001 Johns Hopkins University, Baltimore, MD 
Area:
Public Health, Genetics
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Year Citation  Score
2020 Dikilitas O, Schaid DJ, Kosel ML, Carroll RJ, Chute CG, Denny JA, Fedotov A, Feng Q, Hakonarson H, Jarvik GP, Lee MTM, Pacheco JA, Rowley R, Sleiman PM, Stein CM, ... ... Manolio TA, et al. Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups. American Journal of Human Genetics. 106: 707-716. PMID 32386537 DOI: 10.1016/J.Ajhg.2020.04.002  0.404
2019 Wise AL, Manolio TA, Mensah GA, Peterson JF, Roden DM, Tamburro C, Williams MS, Green ED. Genomic medicine for undiagnosed diseases. Lancet (London, England). PMID 31395441 DOI: 10.1016/S0140-6736(19)31274-7  0.343
2019 Manolio TA, Rowley R, Williams MS, Roden D, Ginsburg GS, Bult C, Chisholm RL, Deverka PA, McLeod HL, Mensah GA, Relling MV, Rodriguez LL, Tamburro C, Green ED. Opportunities, resources, and techniques for implementing genomics in clinical care. Lancet (London, England). PMID 31395439 DOI: 10.1016/S0140-6736(19)31140-7  0.355
2019 Manolio TA. Using the Data We Have: Improving Diversity in Genomic Research. American Journal of Human Genetics. 105: 233-236. PMID 31374201 DOI: 10.1016/J.Ajhg.2019.07.008  0.321
2019 Safarova MS, Satterfield BA, Fan X, Austin EE, Ye Z, Bastarache L, Zheng N, Ritchie MD, Borthwick KM, Williams MS, Larson EB, Scrol A, Jarvik GP, Crosslin DR, Leppig K, ... ... Manolio TA, et al. A phenome-wide association study to discover pleiotropic effects of , , and . Npj Genomic Medicine. 4: 3. PMID 30774981 DOI: 10.1038/S41525-019-0078-7  0.365
2019 Stark Z, Dolman L, Manolio TA, Ozenberger B, Hill SL, Caulfied MJ, Levy Y, Glazer D, Wilson J, Lawler M, Boughtwood T, Braithwaite J, Goodhand P, Birney E, North KN. Integrating Genomics into Healthcare: A Global Responsibility. American Journal of Human Genetics. 104: 13-20. PMID 30609404 DOI: 10.1016/J.Ajhg.2018.11.014  0.309
2018 Manolio TA. UK Biobank debuts as a powerful resource for genomic research. Nature Medicine. 24: 1792-1794. PMID 30510254 DOI: 10.1038/S41591-018-0276-3  0.34
2018 Sapp JC, Johnston JJ, Driscoll K, Heidlebaugh AR, Miren Sagardia A, Dogbe DN, Umstead KL, Turbitt E, Alevizos I, Baron J, Bönnemann C, Brooks B, Donkervoort S, Jee YH, Linehan WM, ... ... Manolio TA, et al. Evaluation of Recipients of Positive and Negative Secondary Findings Evaluations in a Hybrid CLIA-Research Sequencing Pilot. American Journal of Human Genetics. PMID 30122538 DOI: 10.1016/J.Ajhg.2018.07.018  0.31
2018 White KD, Abe R, Ardern-Jones M, Beachkofsky T, Bouchard C, Carleton B, Chodosh J, Cibotti R, Davis R, Denny JC, Dodiuk-Gad RP, Ergen EN, Goldman JL, Holmes JH, Hung SI, ... ... Manolio TA, et al. SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation. The Journal of Allergy and Clinical Immunology. in Practice. 6: 38-69. PMID 29310768 DOI: 10.1016/J.Jaip.2017.11.023  0.303
2017 Hindorff LA, Bonham VL, Brody LC, Ginoza MEC, Hutter CM, Manolio TA, Green ED. Prioritizing diversity in human genomics research. Nature Reviews. Genetics. PMID 29151588 DOI: 10.1038/Nrg.2017.89  0.337
2017 Manolio TA. In Retrospect: A decade of shared genomic associations. Nature. 546: 360-361. PMID 28617469 DOI: 10.1038/546360A  0.376
2017 Manolio TA, Fowler DM, Starita LM, Haendel MA, MacArthur DG, Biesecker LG, Worthey E, Chisholm RL, Green ED, Jacob HJ, McLeod HL, Roden D, Rodriguez LL, Williams MS, Cooper GM, et al. Bedside Back to Bench: Building Bridges between Basic and Clinical Genomic Research. Cell. 169: 6-12. PMID 28340351 DOI: 10.1016/J.Cell.2017.03.005  0.364
2017 Nadkarni GN, Galarneau G, Ellis SB, Nadukuru R, Zhang J, Scott SA, Schurmann C, Li R, Rasmussen-Torvik LJ, Kho AN, Hayes MG, Pacheco JA, Manolio TA, Chisholm RL, Roden DM, et al. Apolipoprotein L1 Variants and Blood Pressure Traits in African Americans. Journal of the American College of Cardiology. 69: 1564-1574. PMID 28335839 DOI: 10.1016/J.Jacc.2017.01.040  0.322
2016 Manolio TA. Implementing genomics and pharmacogenomics in the clinic: The National Human Genome Research Institute's genomic medicine portfolio. Atherosclerosis. PMID 27612677 DOI: 10.1016/J.Atherosclerosis.2016.08.034  0.346
2016 Green RC, Goddard KA, Jarvik GP, Amendola LM, Appelbaum PS, Berg JS, Bernhardt BA, Biesecker LG, Biswas S, Blout CL, Bowling KM, Brothers KB, Burke W, Caga-Anan CF, Chinnaiyan AM, ... ... Manolio TA, et al. Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine. American Journal of Human Genetics. 99: 246. PMID 27392080 DOI: 10.1016/J.Ajhg.2016.06.002  0.3
2016 Green RC, Goddard KA, Jarvik GP, Amendola LM, Appelbaum PS, Berg JS, Bernhardt BA, Biesecker LG, Biswas S, Blout CL, Bowling KM, Brothers KB, Burke W, Caga-Anan CF, Chinnaiyan AM, ... ... Manolio TA, et al. Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine. American Journal of Human Genetics. PMID 27181682 DOI: 10.1016/J.Ajhg.2016.04.011  0.347
2016 Bush WS, Crosslin DR, Obeng AO, Wallace J, Almoguera B, Basford MA, Bielinski SJ, Carrell DS, Connolly JJ, Crawford D, Doheny KF, Gallego CJ, Gordon AS, Keating B, Kirby J, ... ... Manolio T, et al. Genetic Variation among 82 Pharmacogenes: the PGRN-Seq data from the eMERGE Network. Clinical Pharmacology and Therapeutics. PMID 26857349 DOI: 10.1002/Cpt.350  0.328
2016 Van Driest SL, Wells QS, Stallings S, Bush WS, Gordon A, Nickerson DA, Kim JH, Crosslin DR, Jarvik GP, Carrell DS, Ralston JD, Larson EB, Bielinski SJ, Olson JE, Ye Z, ... ... Manolio TA, et al. Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records. Jama. 315: 47-57. PMID 26746457 DOI: 10.1001/Jama.2015.17701  0.32
2016 Weitzel KW, Alexander M, Bernhardt BA, Calman N, Carey DJ, Cavallari LH, Field JR, Hauser D, Junkins HA, Levin PA, Levy K, Madden EB, Manolio TA, Odgis J, Orlando LA, et al. The IGNITE network: a model for genomic medicine implementation and research. Bmc Medical Genomics. 9: 1. PMID 26729011 DOI: 10.1186/S12920-015-0162-5  0.32
2015 Riley WT, Nilsen WJ, Manolio TA, Masys DR, Lauer M. News from the NIH: potential contributions of the behavioral and social sciences to the precision medicine initiative. Translational Behavioral Medicine. 5: 243-6. PMID 26327928 DOI: 10.1007/S13142-015-0320-5  0.319
2015 Mosley JD, Shaffer CM, Van Driest SL, Weeke PE, Wells QS, Karnes JH, Velez Edwards DR, Wei WQ, Teixeira PL, Bastarache L, Crawford DC, Li R, Manolio TA, Bottinger EP, McCarty CA, et al. A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough. The Pharmacogenomics Journal. PMID 26169577 DOI: 10.1038/Tpj.2015.51  0.322
2015 Manolio TA, Abramowicz M, Al-Mulla F, Anderson W, Balling R, Berger AC, Bleyl S, Chakravarti A, Chantratita W, Chisholm RL, W Dissanayake VH, Dunn M, Dzau VJ, Han BG, Hubbard T, et al. Global implementation of genomic medicine: We are not alone. Science Translational Medicine. 7: 290ps13. PMID 26041702 DOI: 10.1126/Scitranslmed.Aab0194  0.334
2014 Rasmussen-Torvik LJ, Stallings SC, Gordon AS, Almoguera B, Basford MA, Bielinski SJ, Brautbar A, Brilliant MH, Carrell DS, Connolly JJ, Crosslin DR, Doheny KF, Gallego CJ, Gottesman O, Kim DS, ... ... Manolio T, et al. Design and anticipated outcomes of the eMERGE-PGx project: a multicenter pilot for preemptive pharmacogenomics in electronic health record systems. Clinical Pharmacology and Therapeutics. 96: 482-9. PMID 24960519 DOI: 10.1038/Clpt.2014.137  0.318
2014 Feero WG, Manolio TA, Khoury MJ. Translational research is a key to nongeneticist physicians' genomics education. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 16: 871-3. PMID 24875299 DOI: 10.1038/Gim.2014.67  0.328
2014 MacArthur DG, Manolio TA, Dimmock DP, Rehm HL, Shendure J, Abecasis GR, Adams DR, Altman RB, Antonarakis SE, Ashley EA, Barrett JC, Biesecker LG, Conrad DF, Cooper GM, Cox NJ, et al. Guidelines for investigating causality of sequence variants in human disease. Nature. 508: 469-76. PMID 24759409 DOI: 10.1038/Nature13127  0.372
2014 Ramos EM, Din-Lovinescu C, Berg JS, Brooks LD, Duncanson A, Dunn M, Good P, Hubbard TJ, Jarvik GP, O'Donnell C, Sherry ST, Aronson N, Biesecker LG, Blumberg B, Calonge N, ... ... Manolio TA, et al. Characterizing genetic variants for clinical action. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 166: 93-104. PMID 24634402 DOI: 10.1002/Ajmg.C.31386  0.351
2014 Manolio TA, Green ED. Leading the way to genomic medicine. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 166: 1-7. PMID 24619573 DOI: 10.1002/Ajmg.C.31384  0.324
2014 Welter D, MacArthur J, Morales J, Burdett T, Hall P, Junkins H, Klemm A, Flicek P, Manolio T, Hindorff L, Parkinson H. The NHGRI GWAS Catalog, a curated resource of SNP-trait associations. Nucleic Acids Research. 42: D1001-6. PMID 24316577 DOI: 10.1093/Nar/Gkt1229  0.301
2013 Denny JC, Bastarache L, Ritchie MD, Carroll RJ, Zink R, Mosley JD, Field JR, Pulley JM, Ramirez AH, Bowton E, Basford MA, Carrell DS, Peissig PL, Kho AN, Pacheco JA, ... ... Manolio TA, et al. Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data. Nature Biotechnology. 31: 1102-10. PMID 24270849 DOI: 10.1038/Nbt.2749  0.377
2013 Yu B, Zheng Y, Alexander D, Manolio TA, Alonso A, Nettleton JA, Boerwinkle E. Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study. Genetic Epidemiology. 37: 840-5. PMID 23934736 DOI: 10.1002/Gepi.21752  0.358
2013 Manolio TA. Bringing genome-wide association findings into clinical use. Nature Reviews. Genetics. 14: 549-58. PMID 23835440 DOI: 10.1038/Nrg3523  0.361
2013 Gottesman O, Kuivaniemi H, Tromp G, Faucett WA, Li R, Manolio TA, Sanderson SC, Kannry J, Zinberg R, Basford MA, Brilliant M, Carey DJ, Chisholm RL, Chute CG, Connolly JJ, et al. The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 15: 761-71. PMID 23743551 DOI: 10.1038/Gim.2013.72  0.327
2013 Ding K, de Andrade M, Manolio TA, Crawford DC, Rasmussen-Torvik LJ, Ritchie MD, Denny JC, Masys DR, Jouni H, Pachecho JA, Kho AN, Roden DM, Chisholm R, Kullo IJ. Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study. G3 (Bethesda, Md.). 3: 1061-8. PMID 23696099 DOI: 10.1534/G3.113.006452  0.353
2013 Ramos EM, Din-Lovinescu C, Bookman EB, McNeil LJ, Baker CC, Godynskiy G, Harris EL, Lehner T, McKeon C, Moss J, Starks VL, Sherry ST, Manolio TA, Rodriguez LL. A mechanism for controlled access to GWAS data: experience of the GAIN Data Access Committee. American Journal of Human Genetics. 92: 479-88. PMID 23561843 DOI: 10.1016/J.Ajhg.2012.08.034  0.325
2013 Ritchie MD, Denny JC, Zuvich RL, Crawford DC, Schildcrout JS, Bastarache L, Ramirez AH, Mosley JD, Pulley JM, Basford MA, Bradford Y, Rasmussen LV, Pathak J, Chute CG, Kullo IJ, ... ... Manolio TA, et al. Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk. Circulation. 127: 1377-85. PMID 23463857 DOI: 10.1161/Circulationaha.112.000604  0.308
2013 Manolio TA, Chisholm RL, Ozenberger B, Roden DM, Williams MS, Wilson R, Bick D, Bottinger EP, Brilliant MH, Eng C, Frazer KA, Korf B, Ledbetter DH, Lupski JR, Marsh C, et al. Implementing genomic medicine in the clinic: the future is here. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 15: 258-67. PMID 23306799 DOI: 10.1097/01.Ogx.0000435523.89711.77  0.354
2013 Manolio TA, Collins R. Counterpoint: "streamlined" does not mean simple. American Journal of Epidemiology. 177: 283-4. PMID 23296355 DOI: 10.1093/Aje/Kws417  0.328
2013 Manolio TA, Collins R. Vehement agreement on new models? American Journal of Epidemiology. 177: 290-1. PMID 23296352 DOI: 10.1093/Aje/Kws410  0.338
2013 Kullo IJ, Jarvik GP, Manolio TA, Williams MS, Roden DM. Leveraging the electronic health record to implement genomic medicine. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 15: 270-1. PMID 23018749 DOI: 10.1038/Gim.2012.131  0.343
2012 Liu EY, Buyske S, Aragaki AK, Peters U, Boerwinkle E, Carlson C, Carty C, Crawford DC, Haessler J, Hindorff LA, Marchand LL, Manolio TA, Matise T, Wang W, Kooperberg C, et al. Genotype imputation of Metabochip SNPs using a study-specific reference panel of ~4,000 haplotypes in African Americans from the Women's Health Initiative. Genetic Epidemiology. 36: 107-17. PMID 22851474 DOI: 10.1002/Gepi.21603  0.317
2012 Buyske S, Wu Y, Carty CL, Cheng I, Assimes TL, Dumitrescu L, Hindorff LA, Mitchell S, Ambite JL, Boerwinkle E, Buzkova P, Carlson CS, Cochran B, Duggan D, Eaton CB, ... ... Manolio TA, et al. Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study. Plos One. 7: e35651. PMID 22539988 DOI: 10.1371/Journal.Pone.0035651  0.329
2012 Rice JP, Hartz SM, Agrawal A, Almasy L, Bennett S, Breslau N, Bucholz KK, Doheny KF, Edenberg HJ, Goate AM, Hesselbrock V, Howells WB, Johnson EO, Kramer J, Krueger RF, ... ... Manolio TA, et al. CHRNB3 is more strongly associated with Fagerström test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results. Addiction (Abingdon, England). 107: 2019-28. PMID 22524403 DOI: 10.1111/J.1360-0443.2012.03922.X  0.32
2012 Manolio TA, Weis BK, Cowie CC, Hoover RN, Hudson K, Kramer BS, Berg C, Collins R, Ewart W, Gaziano JM, Hirschfeld S, Marcus PM, Masys D, McCarty CA, McLaughlin J, et al. New models for large prospective studies: is there a better way? American Journal of Epidemiology. 175: 859-66. PMID 22411865 DOI: 10.1093/Aje/Kwr453  0.318
2012 Manolio TA, Chanock SJ. The riddle of intergenic disease-associated loci. Cell Cycle (Georgetown, Tex.). 11: 15-6. PMID 22193034 DOI: 10.4161/Cc.11.1.18731  0.338
2012 Ntzani EE, Liberopoulos G, Manolio TA, Ioannidis JP. Consistency of genome-wide associations across major ancestral groups. Human Genetics. 131: 1057-71. PMID 22183176 DOI: 10.1007/S00439-011-1124-4  0.355
2011 Zuvich RL, Armstrong LL, Bielinski SJ, Bradford Y, Carlson CS, Crawford DC, Crenshaw AT, de Andrade M, Doheny KF, Haines JL, Hayes MG, Jarvik GP, Jiang L, Kullo IJ, Li R, ... ... Manolio TA, et al. Pitfalls of merging GWAS data: lessons learned in the eMERGE network and quality control procedures to maintain high data quality. Genetic Epidemiology. 35: 887-98. PMID 22125226 DOI: 10.1002/Gepi.20639  0.331
2011 Sivakumaran S, Agakov F, Theodoratou E, Prendergast JG, Zgaga L, Manolio T, Rudan I, McKeigue P, Wilson JF, Campbell H. Abundant pleiotropy in human complex diseases and traits. American Journal of Human Genetics. 89: 607-18. PMID 22077970 DOI: 10.1016/J.Ajhg.2011.10.004  0.358
2011 Denny JC, Crawford DC, Ritchie MD, Bielinski SJ, Basford MA, Bradford Y, Chai HS, Bastarache L, Zuvich R, Peissig P, Carrell D, Ramirez AH, Pathak J, Wilke RA, Rasmussen L, ... ... Manolio TA, et al. Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies. American Journal of Human Genetics. 89: 529-42. PMID 21981779 DOI: 10.1016/J.Ajhg.2011.09.008  0.331
2011 Manolio TA, Green ED. Genomics reaches the clinic: from basic discoveries to clinical impact. Cell. 147: 14-6. PMID 21962499 DOI: 10.1016/J.Cell.2011.09.012  0.336
2011 Craig DW, Goor RM, Wang Z, Paschall J, Ostell J, Feolo M, Sherry ST, Manolio TA. Assessing and managing risk when sharing aggregate genetic variant data. Nature Reviews. Genetics. 12: 730-6. PMID 21921928 DOI: 10.1038/Nrg3067  0.361
2011 Matise TC, Ambite JL, Buyske S, Carlson CS, Cole SA, Crawford DC, Haiman CA, Heiss G, Kooperberg C, Marchand LL, Manolio TA, North KE, Peters U, Ritchie MD, Hindorff LA, et al. The Next PAGE in understanding complex traits: design for the analysis of Population Architecture Using Genetics and Epidemiology (PAGE) Study. American Journal of Epidemiology. 174: 849-59. PMID 21836165 DOI: 10.1093/Aje/Kwr160  0.379
2011 Dumitrescu L, Carty CL, Taylor K, Schumacher FR, Hindorff LA, Ambite JL, Anderson G, Best LG, Brown-Gentry K, B?žková P, Carlson CS, Cochran B, Cole SA, Devereux RB, Duggan D, ... ... Manolio TA, et al. Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study. Plos Genetics. 7: e1002138. PMID 21738485 DOI: 10.1371/Journal.Pgen.1002138  0.333
2011 Kullo IJ, Ding K, Shameer K, McCarty CA, Jarvik GP, Denny JC, Ritchie MD, Ye Z, Crosslin DR, Chisholm RL, Manolio TA, Chute CG. Complement receptor 1 gene variants are associated with erythrocyte sedimentation rate. American Journal of Human Genetics. 89: 131-8. PMID 21700265 DOI: 10.1016/J.Ajhg.2011.05.019  0.312
2011 Yang J, Manolio TA, Pasquale LR, Boerwinkle E, Caporaso N, Cunningham JM, de Andrade M, Feenstra B, Feingold E, Hayes MG, Hill WG, Landi MT, Alonso A, Lettre G, Lin P, et al. Genome partitioning of genetic variation for complex traits using common SNPs. Nature Genetics. 43: 519-25. PMID 21552263 DOI: 10.1038/Ng.823  0.3
2011 Kho AN, Pacheco JA, Peissig PL, Rasmussen L, Newton KM, Weston N, Crane PK, Pathak J, Chute CG, Bielinski SJ, Kullo IJ, Li R, Manolio TA, Chisholm RL, Denny JC. Electronic medical records for genetic research: results of the eMERGE consortium. Science Translational Medicine. 3: 79re1. PMID 21508311 DOI: 10.1126/Scitranslmed.3001807  0.33
2011 Hindorff LA, Gillanders EM, Manolio TA. Genetic architecture of cancer and other complex diseases: lessons learned and future directions. Carcinogenesis. 32: 945-54. PMID 21459759 DOI: 10.1093/Carcin/Bgr056  0.303
2011 Bookman EB, McAllister K, Gillanders E, Wanke K, Balshaw D, Rutter J, Reedy J, Shaughnessy D, Agurs-Collins T, Paltoo D, Atienza A, Bierut L, Kraft P, Fallin MD, Perera F, ... ... Manolio TA, et al. Gene-environment interplay in common complex diseases: forging an integrative model—recommendations from an NIH workshop. Genetic Epidemiology. 35: 217-25. PMID 21308768 DOI: 10.1002/Gepi.20571  0.337
2011 Turner S, Armstrong LL, Bradford Y, Carlson CS, Crawford DC, Crenshaw AT, de Andrade M, Doheny KF, Haines JL, Hayes G, Jarvik G, Jiang L, Kullo IJ, Li R, Ling H, ... Manolio TA, et al. Quality control procedures for genome-wide association studies. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit1.19. PMID 21234875 DOI: 10.1002/0471142905.Hg0119S68  0.329
2010 Manolio TA, Collins R. Enhancing the feasibility of large cohort studies. Jama. 304: 2290-1. PMID 21098774 DOI: 10.1001/Jama.2010.1686  0.306
2010 Laurie CC, Doheny KF, Mirel DB, Pugh EW, Bierut LJ, Bhangale T, Boehm F, Caporaso NE, Cornelis MC, Edenberg HJ, Gabriel SB, Harris EL, Hu FB, Jacobs KB, Kraft P, ... ... Manolio TA, et al. Quality control and quality assurance in genotypic data for genome-wide association studies. Genetic Epidemiology. 34: 591-602. PMID 20718045 DOI: 10.1002/Gepi.20516  0.317
2010 Manolio TA. Genomewide association studies and assessment of the risk of disease. The New England Journal of Medicine. 363: 166-76. PMID 20647212 DOI: 10.1056/Nejmra0905980  0.386
2010 Qi L, Cornelis MC, Kraft P, Stanya KJ, Linda Kao WH, Pankow JS, Dupuis J, Florez JC, Fox CS, Paré G, Sun Q, Girman CJ, Laurie CC, Mirel DB, Manolio TA, et al. Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes. Human Molecular Genetics. 19: 2706-15. PMID 20418489 DOI: 10.1093/Hmg/Ddq156  0.313
2010 Cornelis MC, Agrawal A, Cole JW, Hansel NN, Barnes KC, Beaty TH, Bennett SN, Bierut LJ, Boerwinkle E, Doheny KF, Feenstra B, Feingold E, Fornage M, Haiman CA, Harris EL, ... ... Manolio TA, et al. The Gene, Environment Association Studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions. Genetic Epidemiology. 34: 364-72. PMID 20091798 DOI: 10.1002/Gepi.20492  0.378
2010 Yanez ND, Burke GL, Manolio T, Gardin JM, Polak J. Sibling history of myocardial infarction or stroke and risk of cardiovascular disease in the elderly: the Cardiovascular Health Study. Annals of Epidemiology. 19: 858-66. PMID 19944349 DOI: 10.1016/J.Annepidem.2009.07.095  0.363
2009 Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, Cho JH, Guttmacher AE, Kong A, Kruglyak L, Mardis E, et al. Finding the missing heritability of complex diseases. Nature. 461: 747-53. PMID 19812666 DOI: 10.1038/Nature08494  0.382
2009 Manolio TA, Collins FS. The HapMap and genome-wide association studies in diagnosis and therapy. Annual Review of Medicine. 60: 443-56. PMID 19630580 DOI: 10.1146/Annurev.Med.60.061907.093117  0.404
2009 Biesecker LG, Mullikin JC, Facio FM, Turner C, Cherukuri PF, Blakesley RW, Bouffard GG, Chines PS, Cruz P, Hansen NF, Teer JK, Maskeri B, Young AC, Manolio TA, et al. The ClinSeq Project: piloting large-scale genome sequencing for research in genomic medicine. Genome Research. 19: 1665-74. PMID 19602640 DOI: 10.1101/Gr.092841.109  0.56
2009 DiMartino LD, Hammill BG, Curtis LH, Gottdiener JS, Manolio TA, Powe NR, Schulman KA. External validity of the cardiovascular health study: a comparison with the Medicare population. Medical Care. 47: 916-23. PMID 19597373 DOI: 10.1097/Mlr.0B013E318197B104  0.366
2009 Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, Collins FS, Manolio TA. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proceedings of the National Academy of Sciences of the United States of America. 106: 9362-7. PMID 19474294 DOI: 10.1073/Pnas.0903103106  0.368
2009 Khoury MJ, Feero WG, Reyes M, Citrin T, Freedman A, Leonard D, Burke W, Coates R, Croyle RT, Edwards K, Kardia S, McBride C, Manolio T, Randhawa G, Rasooly R, et al. The genomic applications in practice and prevention network. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 11: 488-94. PMID 19471162 DOI: 10.1097/Gim.0B013E3181A551Cc  0.321
2009 Manolio TA. Collaborative genome-wide association studies of diverse diseases: programs of the NHGRI's office of population genomics. Pharmacogenomics. 10: 235-41. PMID 19207024 DOI: 10.2217/14622416.10.2.235  0.37
2009 Manolio TA. Cohort studies and the genetics of complex disease. Nature Genetics. 41: 5-6. PMID 19112455 DOI: 10.1038/Ng0109-5  0.305
2009 Burton PR, Hansell AL, Fortier I, Manolio TA, Khoury MJ, Little J, Elliott P. Size matters: just how big is BIG?: Quantifying realistic sample size requirements for human genome epidemiology. International Journal of Epidemiology. 38: 263-73. PMID 18676414 DOI: 10.1093/Ije/Dyn147  0.317
2008 Manolio TA, Brooks LD, Collins FS. A HapMap harvest of insights into the genetics of common disease. The Journal of Clinical Investigation. 118: 1590-605. PMID 18451988 DOI: 10.1172/Jci34772  0.376
2008 Pearte CA, Myerson M, Coresh J, McNamara RL, Rosamond W, Taylor H, Manolio TA. Variation and temporal trends in the use of diagnostic testing during hospitalization for acute myocardial infarction by age, gender, race, and geography (the Atherosclerosis Risk In Communities Study). The American Journal of Cardiology. 101: 1219-25. PMID 18435947 DOI: 10.1016/J.Amjcard.2008.01.001  0.323
2007 Manolio TA. Study designs to enhance identification of genetic factors in healthy aging. Nutrition Reviews. 65: S228-33. PMID 18240554 DOI: 10.1111/J.1753-4887.2007.Tb00368.X  0.402
2007 Manolio TA, Rodriguez LL, Brooks L, Abecasis G, Ballinger D, Daly M, Donnelly P, Faraone SV, Frazer K, Gabriel S, Gejman P, et al. New models of collaboration in genome-wide association studies: the Genetic Association Information Network. Nature Genetics. 39: 1045-51. PMID 17728769 DOI: 10.1038/Ng2127  0.346
2007 Moran A, Diez Roux AV, Jackson SA, Kramer H, Manolio TA, Shrager S, Shea S. Acculturation is associated with hypertension in a multiethnic sample. American Journal of Hypertension. 20: 354-63. PMID 17386340 DOI: 10.1016/J.Amjhyper.2006.09.025  0.301
2007 Aboyans V, Criqui MH, McClelland RL, Allison MA, McDermott MM, Goff DC, Manolio TA. Intrinsic contribution of gender and ethnicity to normal ankle-brachial index values: the Multi-Ethnic Study of Atherosclerosis (MESA). Journal of Vascular Surgery. 45: 319-27. PMID 17264011 DOI: 10.1016/J.Jvs.2006.10.032  0.301
2007 Goff DC, Brass L, Braun LT, Croft JB, Flesch JD, Fowkes FG, Hong Y, Howard V, Huston S, Jencks SF, Luepker R, Manolio T, O'Donnell C, Robertson RM, Rosamond W, et al. Essential features of a surveillance system to support the prevention and management of heart disease and stroke: a scientific statement from the American Heart Association Councils on Epidemiology and Prevention, Stroke, and Cardiovascular Nursing and the Interdisciplinary Working Groups on Quality of Care and Outcomes Research and Atherosclerotic Peripheral Vascular Disease. Circulation. 115: 127-55. PMID 17179025 DOI: 10.1161/Circulationaha.106.179904  0.343
2007 Longstreth W, Larsen EK, Klein R, Wong TY, Sharrett AR, Lefkowitz D, Manolio TA. Associations between findings on cranial magnetic resonance imaging and retinal photography in the elderly: the Cardiovascular Health Study. American Journal of Epidemiology. 165: 78-84. PMID 17041135 DOI: 10.1093/Aje/Kwj350  0.332
2007 Kuller LH, Arnold AM, Longstreth WT, Manolio TA, O'Leary DH, Burke GL, Fried LP, Newman AB. White matter grade and ventricular volume on brain MRI as markers of longevity in the cardiovascular health study. Neurobiology of Aging. 28: 1307-15. PMID 16857296 DOI: 10.1016/J.Neurobiolaging.2006.06.010  0.347
2006 Green D, Cushman M, Dermond N, Johnson EA, Castro C, Arnett D, Hill J, Manolio TA. Obtaining informed consent for genetic studies: The multiethnic study of atherosclerosis. American Journal of Epidemiology. 164: 845-51. PMID 16928727 DOI: 10.1093/Aje/Kwj286  0.305
2006 Pearte CA, Furberg CD, O'Meara ES, Psaty BM, Kuller L, Powe NR, Manolio T. Characteristics and baseline clinical predictors of future fatal versus nonfatal coronary heart disease events in older adults: the Cardiovascular Health Study. Circulation. 113: 2177-85. PMID 16651468 DOI: 10.1161/Circulationaha.105.610352  0.356
2006 Bookman EB, Langehorne AA, Eckfeldt JH, Glass KC, Jarvik GP, Klag M, Koski G, Motulsky A, Wilfond B, Manolio TA, Fabsitz RR, Luepker RV. Reporting genetic results in research studies: summary and recommendations of an NHLBI working group. American Journal of Medical Genetics. Part A. 140: 1033-40. PMID 16575896 DOI: 10.1002/Ajmg.A.31195  0.368
2006 Thom T, Haase N, Rosamond W, Howard VJ, Rumsfeld J, Manolio T, Zheng ZJ, Flegal K, O'Donnell C, Kittner S, Lloyd-Jones D, Goff DC, Hong Y. Heart disease and stroke statistics - 2006 Update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee Circulation. 113: e85-e151. PMID 16407573 DOI: 10.1161/Circulationaha.105.171600  0.369
2006 Kuller LH, Arnold AM, Psaty BM, Robbins JA, O'Leary DH, Tracy RP, Burke GL, Manolio TA, Chaves PH. 10-year follow-up of subclinical cardiovascular disease and risk of coronary heart disease in the Cardiovascular Health Study. Archives of Internal Medicine. 166: 71-8. PMID 16401813 DOI: 10.1001/Archinte.166.1.71  0.358
2006 Gottdiener JS, Kitzman DW, Aurigemma GP, Arnold AM, Manolio TA. Left atrial volume, geometry, and function in systolic and diastolic heart failure of persons > or =65 years of age (the cardiovascular health study). The American Journal of Cardiology. 97: 83-9. PMID 16377289 DOI: 10.1016/J.Amjcard.2005.07.126  0.312
2006 Barasch E, Gottdiener JS, Larsen EK, Chaves PH, Newman AB, Manolio TA. Clinical significance of calcification of the fibrous skeleton of the heart and aortosclerosis in community dwelling elderly. The Cardiovascular Health Study (CHS). American Heart Journal. 151: 39-47. PMID 16368289 DOI: 10.1016/J.Ahj.2005.03.052  0.395
2006 Cao JJ, Barzilay JI, Peterson D, Manolio TA, Psaty BM, Kuller L, Wexler J, Bleyer AJ, Cushman M. The association of microalbuminuria with clinical cardiovascular disease and subclinical atherosclerosis in the elderly: the Cardiovascular Health Study. Atherosclerosis. 187: 372-7. PMID 16242696 DOI: 10.1016/J.Atherosclerosis.2005.09.015  0.39
2005 Seliger SL, Longstreth WT, Katz R, Manolio T, Fried LF, Shlipak M, Stehman-Breen CO, Newman A, Sarnak M, Gillen DL, Bleyer A, Siscovick DS. Cystatin C and subclinical brain infarction. Journal of the American Society of Nephrology : Jasn. 16: 3721-7. PMID 16236809 DOI: 10.1681/Asn.2005010006  0.306
2005 Kaplan RC, Tirschwell DL, Longstreth WT, Manolio TA, Heckbert SR, Lefkowitz D, El-Saed A, Psaty BM. Vascular events, mortality, and preventive therapy following ischemic stroke in the elderly Neurology. 65: 835-842. PMID 16186519 DOI: 10.1212/01.Wnl.0000176058.09848.Bb  0.322
2005 Kennedy M, Solomon C, Manolio TA, Criqui MH, Newman AB, Polak JF, Burke GL, Enright P, Cushman M. Risk factors for declining ankle-brachial index in men and women 65 years or older: the Cardiovascular Health Study. Archives of Internal Medicine. 165: 1896-902. PMID 16157835 DOI: 10.1001/Archinte.165.16.1896  0.379
2005 Cushman M, Arnold AM, Psaty BM, Manolio TA, Kuller LH, Burke GL, Polak JF, Tracy RP. C-reactive protein and the 10-year incidence of coronary heart disease in older men and women: the cardiovascular health study. Circulation. 112: 25-31. PMID 15983251 DOI: 10.1161/Circulationaha.104.504159  0.353
2005 Shlipak MG, Fried LF, Cushman M, Manolio TA, Peterson D, Stehman-Breen C, Bleyer A, Newman A, Siscovick D, Psaty B. Cardiovascular mortality risk in chronic kidney disease: comparison of traditional and novel risk factors. Jama. 293: 1737-45. PMID 15827312 DOI: 10.1001/Jama.293.14.1737  0.324
2005 Arnold AM, Psaty BM, Kuller LH, Burke GL, Manolio TA, Fried LP, Robbins JA, Kronmal RA. Incidence of cardiovascular disease in older Americans: the cardiovascular health study. Journal of the American Geriatrics Society. 53: 211-8. PMID 15673343 DOI: 10.1111/J.1532-5415.2005.53105.X  0.353
2005 Mozaffarian D, Longstreth WT, Lemaitre RN, Manolio TA, Kuller LH, Burke GL, Siscovick DS. Fish consumption and stroke risk in elderly individuals: the cardiovascular health study. Archives of Internal Medicine. 165: 200-6. PMID 15668367 DOI: 10.1001/Archinte.165.2.200  0.328
2005 Massing MW, Rywik SL, Broda GB, Jasinski B, Pajak A, Tyroler HA, Williams OD, Manolio TA. Cardiovascular mortality and risk factors: Is Poland repeating the US experience of 30 years ago? Prevention and Control. 1: 165-174. DOI: 10.1016/J.Precon.2005.06.003  0.33
2004 Van Der Palen J, Rea TD, Manolio TA, Lumley T, Newman AB, Tracy RP, Enright PL, Psaty BM. Respiratory muscle strength and the risk of incident cardiovascular events Thorax. 59: 1063-1067. PMID 15563706 DOI: 10.1136/Thx.2004.021915  0.36
2004 Elkins JS, O'Meara ES, Longstreth WT, Carlson MC, Manolio TA, Johnston SC. Stroke risk factors and loss of high cognitive function Neurology. 63: 793-799. PMID 15365125 DOI: 10.1212/01.Wnl.0000137014.36689.7F  0.31
2004 Manolio TA, Boerwinkle E, O'Donnell CJ, Wilson AF. Genetics of ultrasonographic carotid atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1567-77. PMID 15256397 DOI: 10.1161/01.Atv.0000138789.11433.C1  0.59
2004 Chaves PH, Kuller LH, O'Leary DH, Manolio TA, Newman AB. Subclinical cardiovascular disease in older adults: insights from the Cardiovascular Health Study. The American Journal of Geriatric Cardiology. 13: 137-51. PMID 15133417 DOI: 10.1111/J.1076-7460.2004.02120.X  0.368
2004 Johnston SC, O'Meara ES, Manolio TA, Lefkowitz D, O'Leary DH, Goldstein S, Carlson MC, Fried LP, Longstreth WT. Cognitive Impairment and Decline Are Associated with Carotid Artery Disease in Patients without Clinically Evident Cerebrovascular Disease Annals of Internal Medicine. 140: 237-247+I34. PMID 14970146 DOI: 10.7326/0003-4819-140-4-200402170-00005  0.313
2004 Shaw LJ, Lewis JF, Hlatky MA, Hsueh WA, Kelsey SF, Klein R, Manolio TA, Sharrett AR, Tracy RP. Women's Ischemic Syndrome Evaluation: current status and future research directions: report of the National Heart, Lung and Blood Institute workshop: October 2-4, 2002: Section 5: gender-related risk factors for ischemic heart disease Circulation. 109. PMID 14970127 DOI: 10.1161/01.Cir.0000116210.70548.2A  0.373
2004 Bairey Merz N, Bonow RO, Sopko G, Balaban RS, Cannon RO, Gordon D, Hand MM, Hayes SN, Lewis JF, Long T, Manolio TA, Maseri A, Nabel EG, Desvigne Nickens P, Pepine CJ, et al. Women's Ischemic Syndrome Evaluation: current status and future research directions: report of the National Heart, Lung and Blood Institute workshop: October 2-4, 2002: executive summary. Circulation. 109: 805-7. PMID 14970120 DOI: 10.1161/01.Cir.0000116205.96440.Fe  0.347
2004 Scuteri A, Manolio TA, Marino EK, Arnold AM, Lakatta EG. Prevalence of specific variant carotid geometric patterns and incidence of cardiovascular events in older persons: The cardiovascular health study (CHS E-131) Journal of the American College of Cardiology. 43: 187-193. PMID 14736436 DOI: 10.1016/J.Jacc.2003.08.035  0.342
2004 Barasch E, Marino EK, Burke GL, Chaves PH, Manolio TA, Gottdiener JS. 885-4 The severity of mitral annular calcification is associated with prevalent cardiovascular disease in the elderly: The cardiovascular health study Journal of the American College of Cardiology. 43: A240. DOI: 10.1016/S0735-1097(04)91023-6  0.369
2003 Luepker RV, Apple FS, Christenson RH, Crow RS, Fortmann SP, Goff D, Goldberg RJ, Hand MM, Jaffe AS, Julian DG, Levy D, Manolio T, Mendis S, Mensah G, Pajak A, et al. Case definitions for acute coronary heart disease in epidemiology and clinical research studies: a statement from the AHA Council on Epidemiology and Prevention; AHA Statistics Committee; World Heart Federation Council on Epidemiology and Prevention; the European Society of Cardiology Working Group on Epidemiology and Prevention; Centers for Disease Control and Prevention; and the National Heart, Lung, and Blood Institute. Circulation. 108: 2543-9. PMID 14610011 DOI: 10.1161/01.Cir.0000100560.46946.Ea  0.354
2003 Manolio T. Novel risk markers and clinical practice. The New England Journal of Medicine. 349: 1587-9. PMID 14573728 DOI: 10.1056/Nejmp038136  0.311
2003 Manolio TA, Barnes KC, Beaty TH, Levett PN, Naidu RP, Wilson AF. Sex differences in heritability of sensitization to Blomia tropicalis in asthma using regression of offspring on midparent (ROMP) methods. Human Genetics. 113: 437-46. PMID 12928863 DOI: 10.1007/S00439-003-1005-6  0.5
2003 Ding J, Nieto FJ, Beauchamp NJ, Longstreth WT, Manolio TA, Hetmanski JB, Fried LP. A prospective analysis of risk factors for white matter disease in the brain stem: The cardiovascular health study Neuroepidemiology. 22: 275-282. PMID 12902622 DOI: 10.1159/000071190  0.311
2003 Manolio TA, Barnes KC, Naidu RP, Levett PN, Beaty TH, Wilson AF. Correlates of sensitization to Blomia tropicalis and Dermatophagoides pteronyssinus in asthma in Barbados. International Archives of Allergy and Immunology. 131: 119-26. PMID 12811020 DOI: 10.1159/000070927  0.468
2003 Wong TY, Klein R, Sharrett AR, Manolio TA, Hubbard LD, Marino EK, Kuller L, Burke G, Tracy RP, Polak JF, Gottdiener JS, Siscovick DS. The prevalence and risk factors of retinal microvascular abnormalities in older persons: The cardiovascular health study Ophthalmology. 110: 658-666. PMID 12689883 DOI: 10.1016/S0161-6420(02)01931-0  0.346
2003 Shlipak MG, Fried LF, Crump C, Bleyer AJ, Manolio TA, Tracy RP, Furberg CD, Psaty BM. Elevations of inflammatory and procoagulant biomarkers in elderly persons with renal insufficiency Circulation. 107: 87-92. PMID 12515748 DOI: 10.1161/01.Cir.0000042700.48769.59  0.321
2002 Psaty BM, Manolio TA, Smith NL, Heckbert SR, Gottdiener JS, Burke GL, Weissfeld J, Enright P, Lumley T, Powe N, Furberg CD. Time trends in high blood pressure control and the use of antihypertensive medications in older adults: The Cardiovascular Health Study Archives of Internal Medicine. 162: 2325-2332. PMID 12418946 DOI: 10.1001/Archinte.162.20.2325  0.325
2002 Manolio TA, Gottdiener JS, Tsang TS, Gardin JM. Left atrial dimensions determined by M-mode echocardiography in black and white older (> or =65 years) adults (The Cardiovascular Health Study). The American Journal of Cardiology. 90: 983-7. PMID 12398966 DOI: 10.1016/S0002-9149(02)02665-6  0.322
2002 Longstreth WT, Dulberg C, Manolio TA, Lewis MR, Beauchamp NJ, O'Leary D, Carr J, Furberg CD. Incidence, manifestations, and predictors of brain infarcts defined by serial cranial magnetic resonance imaging in the elderly: the Cardiovascular Health Study. Stroke; a Journal of Cerebral Circulation. 33: 2376-82. PMID 12364724 DOI: 10.1161/01.Str.0000032241.58727.49  0.32
2002 Shlipak MG, Fried LF, Crump C, Bleyer AJ, Manolio TA, Tracy RP, Furberg CD, Psaty BM. Cardiovascular disease risk status in elderly persons with renal insufficiency Kidney International. 62: 997-1004. PMID 12164883 DOI: 10.1046/J.1523-1755.2002.00522.X  0.379
2002 Manolio TA, Bild DE. Coronary calcium, race, and genes Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 359-360. PMID 11884274 DOI: 10.1161/Hq0302.105366  0.306
2002 Lumley T, Kronmal RA, Cushman M, Manolio TA, Goldstein S. A stroke prediction score in the elderly: validation and Web-based application. Journal of Clinical Epidemiology. 55: 129-36. PMID 11809350 DOI: 10.1016/S0895-4356(01)00434-6  0.335
2001 Bernick C, Kuller L, Dulberg C, Longstreth WT, Manolio T, Beauchamp N, Price T. Silent MRI infarcts and the risk of future stroke: The cardiovascular health study Neurology. 57: 1222-1229. PMID 11591840 DOI: 10.1212/Wnl.57.7.1222  0.32
2001 Rautaharju PM, Nelson JC, Kronmal RA, Zhang ZM, Robbins J, Gottdiener JS, Furberg CD, Manolio T, Fried L. Usefulness of T-axis deviation as an independent risk indicator for incident cardiac events in older men and women free from coronary heart disease (the Cardiovascular Health Study). The American Journal of Cardiology. 88: 118-23. PMID 11448406 DOI: 10.1016/S0002-9149(01)01604-6  0.376
2001 Newman AB, Arnold AM, Burke GL, O'Leary DH, Manolio TA. Cardiovascular disease and mortality in older adults with small abdominal aortic aneurysms detected by ultrasonography: The cardiovascular health study Annals of Internal Medicine. 134: 182-190+I28. PMID 11177330 DOI: 10.7326/0003-4819-134-3-200102060-00008  0.323
2000 Newman AB, Spiekerman CF, Enright P, Lefkowitz D, Manolio T, Reynolds CF, Robbins J. Daytime sleepiness predicts mortality and cardiovascular disease in older adults Journal of the American Geriatrics Society. 48: 115-123. PMID 10682939 DOI: 10.1111/J.1532-5415.2000.Tb03901.X  0.339
2000 Longstreth WT, Arnold AM, Manolio TA, Burke GL, Bryan N, Jungreis CA, O'Leary D, Enright PL, Fried L. Clinical correlates of ventricular and sulcal size on cranial magnetic resonance imaging of 3,301 elderly people: The cardiovascular health study Neuroepidemiology. 19: 30-42. PMID 10654286 DOI: 10.1159/000026235  0.344
2000 McClelland RL, Kronmal RA, Bryan RN, Manolio TA, Herskovits E, Kuller LH, O'Leary DH. Neurologic correlates of infarction-like lesion location on magnetic resonance imaging in the Cardiovascular Health Study Journal of Stroke and Cerebrovascular Diseases. 9: 218-228. DOI: 10.1053/Jscd.2000.16188  0.307
1999 Rywik SL, Manolio TA, Pajak A, Piotrowski W, Davis CE, Broda GB, Kawalec E. Association of lipids and lipoprotein level with total mortality and mortality caused by cardiovascular and cancer diseases (Poland and United States collaborative study on cardiovascular epidemiology). The American Journal of Cardiology. 84: 540-8. PMID 10482152 DOI: 10.1016/S0002-9149(99)00374-4  0.301
1999 Smith NL, Psaty BM, Furberg CD, White R, Lima JAC, Newman AB, Manolio TA. Temporal trends in the use of anticoagulants among older adults with atrial fibrillation Archives of Internal Medicine. 159: 1574-1578. PMID 10421280 DOI: 10.1001/Archinte.159.14.1574  0.329
1999 Haan MN, Shemanski L, Jagust WJ, Manolio TA, Kuller L. The role of APOE epsilon4 in modulating effects of other risk factors for cognitive decline in elderly persons. Jama. 282: 40-6. PMID 10404910 DOI: 10.1001/Jama.282.1.40  0.323
1999 Ellsworth DL, Manolio TA. The Emerging Importance of Genetics in Epidemiologic Research III. Bioinformatics and statistical genetic methods. Annals of Epidemiology. 9: 207-24. PMID 10332927 DOI: 10.1016/S1047-2797(99)00007-1  0.305
1999 White RH, McBurnie MA, Manolio T, Furberg CD, Gardin JM, Kittner SJ, Bovill E, Knepper L. Oral anticoagulation in patients with atrial fibrillation: adherence with guidelines in an elderly cohort. The American Journal of Medicine. 106: 165-71. PMID 10230745 DOI: 10.1016/S0002-9343(98)00389-1  0.344
1999 Newman AB, Shemanski L, Manolio TA, Cushman M, Mittelmark M, Polak JF, Powe NR, Siscovick D. Ankle-arm index as a predictor of cardiovascular disease and mortality in the Cardiovascular Health Study Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 538-545. PMID 10073955 DOI: 10.1161/01.Atv.19.3.538  0.386
1999 Manolio TA, Burke GL, O'Leary DH, Evans G, Beauchamp N, Knepper L, Ward B. Relationships of cerebral MRI findings to ultrasonographic carotid atherosclerosis in older adults: The cardiovascular health study Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 356-365. PMID 9974419 DOI: 10.1161/01.Atv.19.2.356  0.35
1999 Bhadelia RA, Anderson M, Polak JF, Manolio TA, Beauchamp N, Knepper L, O'Leary DH. Prevalence and associations of MRI-demonstrated brain infarcts in elderly subjects with a history of transient ischemic attack: The cardiovascular health study Stroke. 30: 383-388. PMID 9933275 DOI: 10.1161/01.Str.30.2.383  0.353
1999 Ellsworth DL, Manolio TA. The emerging importance of genetics in epidemiologic research. I. Basic concepts in human genetics and laboratory technology. Annals of Epidemiology. 9: 1-16. PMID 9915603 DOI: 10.1016/S1047-2797(98)00047-7  0.353
1999 O'Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults New England Journal of Medicine. 340: 14-22. PMID 9878640 DOI: 10.1056/Nejm199901073400103  0.341
1998 Longstreth WT, Bernick C, Manolio TA, Bryan N, Jungreis CA, Price TR. Lacunar infarcts defined by magnetic resonance imaging of 3660 elderly people: The cardiovascular health study Archives of Neurology. 55: 1217-1225. PMID 9740116 DOI: 10.1001/Archneur.55.9.1217  0.372
1998 Massing MW, Rywik SL, Jasinski B, Manolio TA, Williams OD, Tyroler HA. Opposing national stroke mortality trends in Poland and for African Americans and whites in the United States, 1968 to 1994 Stroke. 29: 1366-1372. PMID 9660388 DOI: 10.1161/01.Str.29.7.1366  0.321
1998 Kuller L, Fisher L, McClelland R, Fried L, Cushman M, Jackson S, Manolio T. Differences in prevalence of and risk factors for subclinical vascular disease among black and white participants in the Cardiovascular Health Study. Arteriosclerosis, Thrombosis, and Vascular Biology. 18: 283-93. PMID 9484995 DOI: 10.1161/01.Atv.18.2.283  0.394
1997 Mosca L, Manson JE, Sutherland SE, Langer RD, Manolio T, Barrett-Connor E. Cardiovascular disease in women: a statement for healthcare professionals from the American Heart Association. Writing Group. Circulation. 96: 2468-82. PMID 9337227 DOI: 10.1161/01.Cir.96.7.2468  0.327
1997 Psaty BM, Manolio TA, Kuller LH, Kronmal RA, Cushman M, Fried LP, White R, Furberg CD, Rautaharju PM. Incidence of and risk factors for atrial fibrillation in older adults Circulation. 96: 2455-2461. PMID 9337224 DOI: 10.1161/01.Cir.96.7.2455  0.374
1997 Manolio TA, Weinmann GG, Buist AS, Furberg CD, Pinsky JL, Hurd SH. Pulmonary function testing in population-based studies American Journal of Respiratory and Critical Care Medicine. 156: 1004-1010. PMID 9310027 DOI: 10.1164/Ajrccm.156.3.9704054  0.309
1997 Howard G, Manolio TA, Burke GL, Wolfson SK, O'Leary DH. Does the association of risk factors and atherosclerosis change with age? An analysis of the combined ARIC and CHS cohorts. The Atherosclerosis Risk in Communities (ARIC) and Cardiovascular Health Study (CHS) investigators. Stroke; a Journal of Cerebral Circulation. 28: 1693-701. PMID 9303011 DOI: 10.1161/01.Str.28.9.1693  0.369
1997 Price TR, Manolio TA, Kronmal RA, Kittner SJ, Yue NC, Robbins J, Anton-Culver H, O'Leary DH. Silent brain infarction on magnetic resonance imaging and neurological abnormalities in community-dwelling older adults: The Cardiovascular Health Study Stroke. 28: 1158-1164. PMID 9183343 DOI: 10.1161/01.Str.28.6.1158  0.33
1997 Newman AB, Enright PL, Manolio TA, Haponik EF, Wahl PW. Sleep disturbance, psychosocial correlates, and cardiovascular disease in 5201 older adults: The Cardiovascular Health Study Journal of the American Geriatrics Society. 45: 1-7. PMID 8994480 DOI: 10.1111/J.1532-5415.1997.Tb00970.X  0.323
1996 Enright PL, Newman AB, Wahl PW, Manolio TA, Haponik EF, Boyle PJ. Prevalence and correlates of snoring and observed apneas in 5,201 older adults. Sleep. 19: 531-8. PMID 8899931 DOI: 10.1093/Sleep/19.7.531  0.347
1996 Manolio TA, Kronmal RA, Burke GL, O'Leary DH, Price TR. Short-term predictors of incident stroke in older adults: The Cardiovascular Health Study Stroke. 27: 1479-1486. PMID 8784116 DOI: 10.1161/01.Str.27.9.1479  0.365
1996 Longstreth WT, Manolio TA, Arnold A, Burke GL, Bryan N, Jungreis CA, Enright PL, O'Leary D, Fried L. Clinical correlates of white matter findings on cranial magnetic resonance imaging of 3301 elderly people: The cardiovascular health study Stroke. 27: 1274-1282. PMID 8711786 DOI: 10.1161/01.Str.27.8.1274  0.353
1996 Rautaharju PM, Manolio TA, Siscovick D, Zhou SH, Gardin JM, Kronmal R, Furberg CD, Borhani NO, Newman A. Utility of new electrocardiographic models for left ventricular mass in older adults Hypertension. 28: 8-15. PMID 8675268 DOI: 10.1161/01.Hyp.28.1.8  0.309
1996 Kronmal RA, Smith VE, O'Leary DH, Polak JF, Gardin JM, Manolio TA. Carotid artery measures are strongly associated with left ventricular mass in older adults (a report from the Cardiovascular Health Study) American Journal of Cardiology. 77: 628-633. PMID 8610615 DOI: 10.1016/S0002-9149(97)89319-8  0.358
1996 Furberg CD, Hennekens CH, Hulley SB, Manolio T, Psaty BM, Whelton PK. 27th Bethesda Conference: matching the intensity of risk factor management with the hazard for coronary disease events. Task Force 2. Clinical epidemiology: the conceptual basis for interpreting risk factors. Journal of the American College of Cardiology. 27: 976-8. PMID 8609363 DOI: 10.1016/0735-1097(96)87730-8  0.308
1996 Jonas HA, Manolio TA. Hormone replacement and cardiovascular disease in older women Journal of Women's Health. 5: 351-361. DOI: 10.1089/Jwh.1996.5.351  0.346
1995 Rautaharju PM, Manolio TA, Furberg CD, Siscovick D, Newman AB, Borhani NO, Gardin JM. Ischemic episodes in 24-h ambulatory electrocardiograms of elderly persons: The cardiovascular health study International Journal of Cardiology. 51: 165-175. PMID 8522413 DOI: 10.1016/0167-5273(95)02414-R  0.362
1995 Gardin JM, Siscovick D, Anton-Culver H, Lynch JC, Smith VE, Klopfenstein HS, Bommer WJ, Fried L, O'Leary D, Manolio TA. Sex, age, and disease affect echocardiographic left ventricular mass and systolic function in the free-living elderly. The Cardiovascular Health Study. Circulation. 91: 1739-48. PMID 7882482 DOI: 10.1161/01.Cir.91.6.1739  0.364
1995 Enright PL, Kronmal RA, Smith VE, Gardin JM, Schenker MB, Manolio TA. Reduced vital capacity in elderly persons with hypertension, coronary heart disease, or left ventricular hypertrophy: The Cardiovascular Health Study Chest. 107: 28-35. PMID 7813294 DOI: 10.1378/Chest.107.1.28  0.377
1995 Manolio TA, Burke GL, Psaty BM, Newman AB, Haan M, Powe N, Tracy RP, O'Leary DH. Black-white differences in subclinical cardiovascular disease among older adults: The cardiovascular health study Journal of Clinical Epidemiology. 48: 1141-1152. PMID 7636516 DOI: 10.1016/0895-4356(94)00240-Q  0.373
1995 Gardin JM, Wagenknecht LE, Anton-Culver H, Flack J, Gidding S, Kurosaki T, Wong ND, Manolio TA. Relationship of cardiovascular risk factors to echocardiographic left ventricular mass in healthy young black and white adult men and women. The CARDIA study. Coronary Artery Risk Development in Young Adults. Circulation. 92: 380-7. PMID 7634452 DOI: 10.1161/01.Cir.92.3.380  0.358
1994 Enrighi PL, Kronmal RA, Manolio TA, Schenker MB, Hyatt RE. Respiratory muscle strength in the elderly: Correlates and reference values American Journal of Respiratory and Critical Care Medicine. 149: 430-438. PMID 8306041 DOI: 10.1164/Ajrccm.149.2.8306041  0.326
1994 Manolio TA, Kronmal RA, Burke GL, Poirier V, O'Leary DH, Gardin JM, Fried LP, Steinberg EP, Bryan RN. Magnetic resonance abnormalities and cardiovascular disease in older adults. The Cardiovascular Health Study. Stroke; a Journal of Cerebral Circulation. 25: 318-27. PMID 8303738 DOI: 10.1161/01.Str.25.2.318  0.347
1994 Kuller L, Borhani N, Furberg C, Gardin J, Manolio T, O'Leary D, Psaty B, Robbins J. Prevalence of subclinical atherosclerosis and cardiovascular disease and association with risk factors in the Cardiovascular Health Study. American Journal of Epidemiology. 139: 1164-79. PMID 8209875 DOI: 10.1093/Oxfordjournals.Aje.A116963  0.392
1994 Manolio TA, Furberg CD, Rautaharju PM, Siscovick D, Newman AB, Borhani NO, Gardin JM, Tabatznik B. Cardiac arrhythmias on 24-h ambulatory electrocardiography in older women and men: The cardiovascular health study Journal of the American College of Cardiology. 23: 916-925. PMID 8106697 DOI: 10.1016/0735-1097(94)90638-6  0.397
1994 Furberg CD, Psaty BM, Manolio TA, Gardin JM, Smith VE, Rautaharju PM. Prevalence of atrial fibrillation in elderly subjects (the Cardiovascular Health Study). The American Journal of Cardiology. 74: 236-41. PMID 8037127 DOI: 10.1016/0002-9149(94)90363-8  0.392
1993 Manolio TA, Ettinger WH, Tracy RP, Kuller LH, Borhani NO, Lynch JC, Fried LP. Epidemiology of low cholesterol levels in older adults. The Cardiovascular Health Study. Circulation. 87: 728-37. PMID 8443893 DOI: 10.1161/01.Cir.87.3.728  0.339
1993 Newman AB, Siscovick DS, Manolio TA, Polak J, Fried LP, Borhani NO, Wolfson SK. Ankle-arm index as a marker of atherosclerosis in the Cardiovascular Health Study. Cardiovascular Heart Study (CHS) Collaborative Research Group. Circulation. 88: 837-45. PMID 8353913 DOI: 10.1161/01.Cir.88.3.837  0.402
1993 Tell GS, Fried LP, Hermanson B, Manolio TA, Newman AB, Borhani NO. Recruitment of adults 65 years and older as participants in the cardiovascular health study Annals of Epidemiology. 3: 358-366. PMID 8275211 DOI: 10.1016/1047-2797(93)90062-9  0.345
1993 Manolio TA, Furberg CD, Shemanski L, Psaty BM, O'Leary DH, Tracy RP, Bush TL. Associations of postmenopausal estrogen use with cardiovascular disease and its risk factors in older women Circulation. 88: 2163-2171. PMID 8222111 DOI: 10.1161/01.Cir.88.5.2163  0.388
1992 Gardin JM, Wong ND, Bommer W, Klopfenstein HS, Smith VE, Tabatznik B, Siscovick D, Lobodzinski S, Anton-Culver H, Manolio TA. Echocardiographic design of a multicenter investigation of free-living elderly subjects: the Cardiovascular Health Study. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 5: 63-72. PMID 1739473 DOI: 10.1016/S0894-7317(14)80105-3  0.378
1992 Manolio TA, Baughman KL, Rodeheffer R, Pearson TA, Bristow JD, Michels VV, Abelmann WH, Harlan WR. Prevalence and etiology of idiopathic dilated cardiomyopathy (summary of a National Heart, Lung, and Blood Institute workshop. The American Journal of Cardiology. 69: 1458-66. PMID 1590237 DOI: 10.1016/0002-9149(92)90901-A  0.346
1992 Scherwitz LW, Perkins LL, Chesney MA, Hughes GH, Sidney S, Manolio TA. Hostility and health behaviors in young adults: the CARDIA Study. Coronary Artery Risk Development in Young Adults Study. American Journal of Epidemiology. 136: 136-45. PMID 1415137 DOI: 10.1093/Oxfordjournals.Aje.A116480  0.372
1992 Manolio TA, Pearson TA, Wenger NK, Barrett-Connor E, Payne GH, Harlan WR. Cholesterol and heart disease in older persons and women review of an NHLBI workshop Annals of Epidemiology. 2: 161-176. PMID 1342259 DOI: 10.1016/1047-2797(92)90051-Q  0.357
1991 Fried LP, Borhani NO, Enright P, Furberg CD, Gardin JM, Kronmal RA, Kuller LH, Manolio TA, Mittelmark MB, Newman A, O'Leary DH, Psaty B, Rautaharju P, Tracy RP, Weiler PG. The cardiovascular health study: Design and rationale Annals of Epidemiology. 1: 263-276. PMID 1669507 DOI: 10.1016/1047-2797(91)90005-W  0.407
1990 Psaty BM, Koepsell TD, Manolio TA, Longstreth WT, Wagner EH, Wahl PW, Kronmal RA. Risk ratios and risk differences in estimating the effect of risk factors for cardiovascular disease in the elderly Journal of Clinical Epidemiology. 43: 961-970. PMID 2213084 DOI: 10.1016/0895-4356(90)90079-5  0.373
1990 Manolio TA, Savage PJ, Burke GL, Liu KA, Wagenknecht LE, Sidney S, Jacobs DR, Roseman JM, Donahue RP, Oberman A. Association of fasting insulin with blood pressure and lipids in young adults. The CARDIA study. Arteriosclerosis (Dallas, Tex.). 10: 430-6. PMID 2188641 DOI: 10.1161/01.Atv.10.3.430  0.302
Low-probability matches (unlikely to be authored by this person)
2010 Boyd H, Feenstra B, Geller F, Feingold E, Ryckman K, Shaffer J, Laurie C, Zhang Q, Doheny K, Pugh E, Manolio T, Marazita M, Melbye M, Murray J, Consortium G. 292 A Genome-Wide Association Study of Spontaneous Preterm Delivery Pediatric Research. 68: 150-150. DOI: 10.1203/00006450-201011001-00292  0.299
2008 Manolio TA, Arnold AM, Post W, Bertoni AG, Schreiner PJ, Sacco RL, Saad MF, Detrano RL, Szklo M. Ethnic differences in the relationship of carotid atherosclerosis to coronary calcification: the Multi-Ethnic Study of Atherosclerosis. Atherosclerosis. 197: 132-8. PMID 17412347 DOI: 10.1016/J.Atherosclerosis.2007.02.030  0.299
2018 Hellwig LD, Turner C, Manolio TA, Haigney M, James CA, Murray B, Szpisjak DF, Muldoon S, Estrada-Veras J, Krokosky A, De Castro MJ. Return of secondary findings in genomic sequencing: Military implications. Molecular Genetics & Genomic Medicine. PMID 30415494 DOI: 10.1002/Mgg3.483  0.299
2009 Jacobs KB, Yeager M, Wacholder S, Craig D, Kraft P, Hunter DJ, Paschal J, Manolio TA, Tucker M, Hoover RN, Thomas GD, Chanock SJ, Chatterjee N. A new statistic and its power to infer membership in a genome-wide association study using genotype frequencies. Nature Genetics. 41: 1253-7. PMID 19801980 DOI: 10.1038/Ng.455  0.299
2006 Manolio TA, Bailey-Wilson JE, Collins FS. Genes, environment and the value of prospective cohort studies. Nature Reviews. Genetics. 7: 812-20. PMID 16983377 DOI: 10.1038/Nrg1919  0.299
1998 Pajak A, Broda G, Manolio TA, Kawalec E, Rywik S, Davis CE, Pikon J, Pytlak A, Thomas RP, Irving SH. Constitutional, biochemical and lifestyle correlates of fibrinogen and factor VII activity in Polish urban and rural populations International Journal of Epidemiology. 27: 953-961. PMID 10024188 DOI: 10.1093/Ije/27.6.953  0.298
2012 Rasmussen-Torvik LJ, Pacheco JA, Wilke RA, Thompson WK, Ritchie MD, Kho AN, Muthalagu A, Hayes MG, Armstrong LL, Scheftner DA, Wilkins JT, Zuvich RL, Crosslin D, Roden DM, Denny JC, ... ... Manolio TA, et al. High density GWAS for LDL cholesterol in African Americans using electronic medical records reveals a strong protective variant in APOE. Clinical and Translational Science. 5: 394-9. PMID 23067351 DOI: 10.1111/J.1752-8062.2012.00446.X  0.297
2011 Craig DW, Goor RM, Wang Z, Paschall J, Ostell J, Feolo M, Sherry ST, Manolio TA. Erratum: Assessing and managing risk when sharing aggregate genetic variant data Nature Reviews Genetics. 12: 801-801. DOI: 10.1038/Nrg3093  0.296
2013 Zheng Y, Yu B, Alexander D, Manolio TA, Aguilar D, Coresh J, Heiss G, Boerwinkle E, Nettleton JA. Associations between metabolomic compounds and incident heart failure among African Americans: the ARIC Study. American Journal of Epidemiology. 178: 534-42. PMID 23788672 DOI: 10.1093/Aje/Kwt004  0.296
2007 Baker ML, Marino Larsen EK, Kuller LH, Klein R, Klein BE, Siscovick DS, Bernick C, Manolio TA, Wong TY. Retinal microvascular signs, cognitive function, and dementia in older persons: the Cardiovascular Health Study. Stroke; a Journal of Cerebral Circulation. 38: 2041-7. PMID 17525385 DOI: 10.1161/Strokeaha.107.483586  0.296
1999 Singh JP, Larson MG, Manolio TA, O'Donnell CJ, Lauer M, Evans JC, Levy D. Blood pressure response during treadmill testing as a risk factor for new-onset hypertension. The Framingham heart study Circulation. 99: 1831-1836. PMID 10199879 DOI: 10.1161/01.Cir.99.14.1831  0.295
1998 Wagenknecht LE, Craven TE, Preisser JS, Manolio TA, Winders S, Hulley SB. Ten-year trends in cigarette smoking among young adults, 1986-1996: The CARDIA study Annals of Epidemiology. 8: 301-307. PMID 9669612 DOI: 10.1016/S1047-2797(97)00211-1  0.294
1996 Jonas HA, Kronmal RA, Psaty BM, Manolio TA, Meilahn EN, Tell GS, Tracy RP, Robbins JA, Anton-Culver H. Current estrogen-progestin and estrogen replacement therapy in elderly women: Association with carotid atherosclerosis Annals of Epidemiology. 6: 314-323. PMID 8876842 DOI: 10.1016/S0378-5122(97)88488-5  0.293
2004 Manolio TA, Cushman M, Gottdiener JS, Dobs A, Kuller LH, Kronmal RA. Predictors of falling cholesterol levels in older adults: the Cardiovascular Health Study. Annals of Epidemiology. 14: 325-31. PMID 15177271 DOI: 10.1016/J.Annepidem.2003.09.006  0.293
2000 Bernick CB, Kuller LH, Longstreth WT, Dulberg C, Manolio TA, Beauchamp NJ, Price TR. Silent Brain MRI Infarcts and Subsequent Stroke Type In the Cardiovascular health Study Stroke. 32: 363-363. DOI: 10.1161/01.Str.32.Suppl_1.363-D  0.293
2001 Sheifer SE, Manolio TA, Gersh BJ. Unrecognized myocardial infarction Annals of Internal Medicine. 135: 801-811. PMID 11694105 DOI: 10.7326/0003-4819-135-9-200111060-00010  0.293
2003 Cao JJ, Thach C, Manolio TA, Psaty BM, Kuller LH, Chaves PH, Polak JF, Sutton-Tyrrell K, Herrington DM, Price TR, Cushman M. C-reactive protein, carotid intima-media thickness, and incidence of ischemic stroke in the elderly: the Cardiovascular Health Study. Circulation. 108: 166-70. PMID 12821545 DOI: 10.1161/01.Cir.0000079160.07364.6A  0.292
2004 Bryson CL, Smith NL, Kuller LH, Chaves PH, Manolio TA, Lewis W, Boyko EJ, Furberg CD, Psaty BM. Risk of congestive heart failure in an elderly population treated with peripheral alpha-1 antagonists. Journal of the American Geriatrics Society. 52: 1648-54. PMID 15450040 DOI: 10.1111/J.1532-5415.2004.52456.X  0.292
1999 Sorlie PD, Thom TJ, Manolio T, Rosenberg HM, Anderson RN, Burke GL. Age-adjusted death rates: consequences of the Year 2000 standard. Annals of Epidemiology. 9: 93-100. PMID 10037552 DOI: 10.1016/S1047-2797(98)00061-1  0.29
2002 Bittner V, Velentgas P, Manolio TA, Psaty BM, Robbins J, Tell GS, Tracy RP. Estrogen replacement therapy and cardiovascular events: the cardiovascular health study Journal of the American College of Cardiology. 39: 162-163. DOI: 10.1016/S0735-1097(02)80719-7  0.29
2013 Bookman EB, Din-Lovinescu C, Worrall BB, Manolio TA, Bennett SN, Laurie C, Mirel DB, Doheny KF, Anderson GL, Wehr K, Weinshilboum R, Chen DT. Incidental genetic findings in randomized clinical trials: recommendations from the Genomics and Randomized Trials Network (GARNET). Genome Medicine. 5: 7. PMID 23363732 DOI: 10.1186/Gm411  0.289
1994 Rautaharju PM, Manolio TA, Psaty BM, Borhani NO, Furberg CD. Correlates of QT prolongation in older adults (the Cardiovascular Health Study) The American Journal of Cardiology. 73: 999-1002. PMID 8184870 DOI: 10.1016/0002-9149(94)90156-2  0.289
1995 Psaty BM, Koepsell TD, Siscovick DS, Smith NL, Heckbert SR, Yanez ND, Borhani NO, Manolio TA, Gardin JM, Gottdiener JS, Rutan GH, Furberg CD. Temporal Patterns of Antihypertensive Medication Use Among Older Adults, 1989 Through 1992: An Effect of the Major Clinical Trials on Clinical Practice? Jama: the Journal of the American Medical Association. 273: 1436-1438. PMID 7723157 DOI: 10.1001/Jama.1995.03520420052037  0.288
1992 Manolio TA, Furberg CD, Wahl PW, Tracy RP, Borhani NO, Gardin JM, Fried LP, O'Leary DH, Kuller LH. Eligibility for cholesterol referral in community-dwelling older adults. The Cardiovascular Health Study. Annals of Internal Medicine. 116: 641-9. PMID 1546864 DOI: 10.7326/0003-4819-116-8-641  0.286
2012 Laurie CC, Laurie CA, Rice K, Doheny KF, Zelnick LR, McHugh CP, Ling H, Hetrick KN, Pugh EW, Amos C, Wei Q, Wang LE, Lee JE, Barnes KC, Hansel NN, ... ... Manolio T, et al. Detectable clonal mosaicism from birth to old age and its relationship to cancer. Nature Genetics. 44: 642-50. PMID 22561516 DOI: 10.1038/Ng.2271  0.285
2017 Manolio TA. Incorporating Whole-Genome Sequencing Into Primary Care: Falling Barriers and Next Steps. Annals of Internal Medicine. PMID 28654971 DOI: 10.7326/M17-1518  0.285
1999 Ellsworth DL, Manolio TA. The emerging importance of genetics in epidemiologic research II. Issues in study design and gene mapping. Annals of Epidemiology. 9: 75-90. PMID 10037550 DOI: 10.1016/S1047-2797(98)00064-7  0.285
2007 Collins FS, Manolio TA. Merging and emerging cohorts: necessary but not sufficient. Nature. 445: 259. PMID 17230172 DOI: 10.1038/445259A  0.285
2011 Bookman EB, Langehorne AA, Eckfeldt JH, Glass KC, Jarvik GP, Klag M, Koski G, Motulsky A, Wilfond B, Manolio TA, Fabsitz RR, Luepker RV. Comment on "Multidimensional results reporting to participants in genomic studies: getting it right". Science Translational Medicine. 3: 70le1. PMID 21325615 DOI: 10.1126/Scitranslmed.3001516  0.285
2017 Rasmussen-Torvik LJ, Almoguera B, Doheny KF, Freimuth RR, Gordon AS, Hakonarson H, Hawkins JB, Husami A, Ivacic L, Kullo IJ, Linderman MD, Manolio TA, Obeng AO, Pellegrino R, Prows CA, et al. Concordance between Research Sequencing and Clinical Pharmacogenetic Genotyping in the eMERGE-PGx Study. The Journal of Molecular Diagnostics : Jmd. PMID 28502727 DOI: 10.1016/J.Jmoldx.2017.04.002  0.285
2019 Manolio TA, Bult CJ, Chisholm RL, Deverka PA, Ginsburg GS, Jarvik GP, McLeod HL, Mensah GA, Relling MV, Roden DM, Rowley R, Tamburro C, Williams MS, Green ED. Genomic Medicine Year in Review: 2019. American Journal of Human Genetics. 105: 1072-1075. PMID 32027834 DOI: 10.1016/J.Ajhg.2019.11.006  0.285
1991 Manolio TA, Savage PJ, Burke GL, Hilner JE, Liu K, Orchard TJ, Sidney S, Oberman A. Correlates of fasting insulin levels in young adults: the CARDIA study. Journal of Clinical Epidemiology. 44: 571-8. PMID 2037862 DOI: 10.1016/0895-4356(91)90221-T  0.284
1997 Pajak A, Williams OD, Broda G, Baczynska E, Rywik S, Davis CE, Kawalec E, Chodkowska E, Irving S, Manolio T. Changes over time in blood lipids and their correlates in Polish rural and urban populations: the Poland-United States Collaborative Study in cardiopulmonary disease epidemiology. Annals of Epidemiology. 7: 115-24. PMID 9099399 DOI: 10.1016/S1047-2797(96)00125-1  0.283
1991 Manolio TA, Levy D, Garrison RJ, Castelli WP, Kannel WB. Relation of alcohol intake to left ventricular mass: The Framingham Study. Journal of the American College of Cardiology. 17: 717-21. PMID 1825213 DOI: 10.1016/S0735-1097(10)80189-5  0.283
2000 Luoto R, Manolio T, Meilahn E, Bhadelia R, Furberg C, Cooper L, Kraut M. Estrogen replacement therapy and MRI-demonstrated cerebral infarcts, white matter changes, and brain atrophy in older women: the Cardiovascular Health Study. Journal of the American Geriatrics Society. 48: 467-72. PMID 10811537 DOI: 10.1111/J.1532-5415.2000.Tb04990.X  0.282
2004 Drazner MH, Rame JE, Marino EK, Gottdiener JS, Kitzman DW, Gardin JM, Manolio TA, Dries DL, Siscovick DS. Increased left ventricular mass is a risk factor for the development of a depressed left ventricular ejection fraction within five years: the Cardiovascular Health Study. Journal of the American College of Cardiology. 43: 2207-15. PMID 15193681 DOI: 10.1016/J.Jacc.2003.11.064  0.282
1996 Rautaharju PM, Manolio TA, Siscovick D, Zhou SH, Gardin JM, Furberg CD, Borhani NO, Newman A. Classification Accuracy of Electrocardiographic Criteria for Left Ventricular Hypertrophy in Normal Weight and Overweight Older Adults Annals of Noninvasive Electrocardiology. 1: 121-132. DOI: 10.1111/J.1542-474X.1996.Tb00271.X  0.282
2006 Elkins JS, Longstreth WT, Manolio TA, Newman AB, Bhadelia RA, Johnston SC. Education and the cognitive decline associated with MRI-defined brain infarct Neurology. 67: 435-440. PMID 16894104 DOI: 10.1212/01.Wnl.0000228246.89109.98  0.282
1990 Dyer AR, Cutter GR, Liu KQ, Armstrong MA, Friedman GD, Hughes GH, Dolce JJ, Raczynski J, Burke G, Manolio T. Alcohol intake and blood pressure in young adults: the CARDIA Study. Journal of Clinical Epidemiology. 43: 1-13. PMID 1969463 DOI: 10.1016/0895-4356(90)90050-Y  0.281
2007 Chanock SJ, Manolio T, Boehnke M, Boerwinkle E, Hunter DJ, Thomas G, Hirschhorn JN, Abecasis G, Altshuler D, Bailey-Wilson JE, Brooks LD, Cardon LR, Daly M, Donnelly P, et al. Replicating genotype-phenotype associations. Nature. 447: 655-60. PMID 17554299 DOI: 10.1038/447655A  0.281
2002 Gottdiener JS, McClelland RL, Marshall R, Shemanski L, Furberg CD, Kitzman DW, Cushman M, Polak J, Gardin JM, Gersh BJ, Aurigemma GP, Manolio TA. Outcome of congestive heart failure in elderly persons: Influence of left ventricular systolic function. The cardiovascular health study Annals of Internal Medicine. 137: 631-639. PMID 12379062 DOI: 10.7326/0003-4819-137-8-200210150-00006  0.281
2011 Longstreth WT, Arnold AM, Kuller LH, Bernick C, Lefkowitz DS, Beauchamp NJ, Manolio TA. Progression of magnetic resonance imaging-defined brain vascular disease predicts vascular events in elderly: the Cardiovascular Health Study. Stroke; a Journal of Cerebral Circulation. 42: 2970-2. PMID 21817135 DOI: 10.1161/Strokeaha.111.622977  0.279
2001 Jackson SA, Burke GL, Thach C, Cushman M, Ives D, Powe N, Manolio TA. Incidence and predictors of coronary heart disease among older African Americans - The cardiovascular health study Journal of the National Medical Association. 93: 423-429. PMID 11730114  0.277
1995 Manolio TA, Cutler JA, Furberg CD, Psaty BM, Whelton PK, Applegate WB. Trends in Pharmacologic Management of Hypertension in the United States Archives of Internal Medicine. 155: 829-837. PMID 7717791 DOI: 10.1001/Archinte.1995.00430080067009  0.277
2006 Foppa M, Duncan BB, Arnett DK, Benjamin EJ, Liebson PR, Manolio TA, Skelton TN. Diabetes, gender, and left ventricular structure in African-Americans: the atherosclerosis risk in communities study. Cardiovascular Ultrasound. 4: 43. PMID 17092348 DOI: 10.1186/1476-7120-4-43  0.274
1986 Beattie C, Christopherson R, Manolio T, Pearson T. MYOCARDIAL ISCHEMIA MAY BE MORE COMMON WITH REGIONAL THAN WITH GENERAL ANESTHESIA IN HIGH RISK PATIENTS Anesthesiology. 65: A519. DOI: 10.1097/00000542-198609001-00517  0.271
2006 Kaplan RC, Tirschwell DL, Longstreth WT, Manolio TA, Heckbert SR, LeValley AJ, Lefkowitz D, El-Saed A, Psaty BM. Blood pressure level and outcomes in adults aged 65 and older with prior ischemic stroke. Journal of the American Geriatrics Society. 54: 1309-16. PMID 16970636 DOI: 10.1111/J.1532-5415.2006.00838.X  0.27
2005 Fox CS, Evans JC, Larson MG, Lloyd-Jones DM, O'Donnell CJ, Sorlie PD, Manolio TA, Kannel WB, Levy D. A comparison of death certificate out-of-hospital coronary heart disease death with physician-adjudicated sudden cardiac death. The American Journal of Cardiology. 95: 856-9. PMID 15781015 DOI: 10.1016/J.Amjcard.2004.12.011  0.269
1992 Furberg CD, Manolio TA, Psaty BM, Bild DE, Borhani NO, Newman A, Tabatznik B, Rautaharju PM. Major electrocardiographic abnormalities in persons aged 65 years and older (the Cardiovascular Health Study). Cardiovascular Health Study Collaborative Research Group. The American Journal of Cardiology. 69: 1329-35. PMID 1585868 DOI: 10.1016/0002-9149(92)91231-R  0.268
2007 Manolio TA, Collins FS. Genes, environment, health, and disease: facing up to complexity. Human Heredity. 63: 63-6. PMID 17283435 DOI: 10.1159/000099178  0.267
2006 Manolio TA. Taking our obligations to research participants seriously: disclosing individual results of genetic research. The American Journal of Bioethics : Ajob. 6: 32-4; author reply W. PMID 17085403 DOI: 10.1080/15265160600935993  0.264
2017 Manolio TA, Hutter CM, Avigan M, Cibotti R, Davis RL, Denny JC, Grenade L, Wheatley LM, Carrington MN, Chantratita W, Chung WH, Dalton AD, Hung SI, Lee MTM, Leeder JS, et al. Research Directions in Genetic Predispositions to Stevens-Johnson Syndrome / Toxic Epidermal Necrolysis. Clinical Pharmacology and Therapeutics. PMID 29105735 DOI: 10.1002/Cpt.890  0.263
1990 Friedman GD, Tekawa I, Grimm RH, Manolio T, Shannon SG, Sidney S. The leucocyte count: correlates and relationship to coronary risk factors: the CARDIA study. International Journal of Epidemiology. 19: 889-93. PMID 2084017 DOI: 10.1093/ije/19.4.889  0.263
2008 Pearson TA, Manolio TA. How to interpret a genome-wide association study. Jama. 299: 1335-44. PMID 18349094 DOI: 10.1001/jama.299.11.1335  0.262
2003 Crainich P, Jenny NS, Tang Z, Arnold AM, Kuller LH, Manolio T, Sharrett AR, Tracy RP. Lack of association of the plasminogen activator inhibitor-1 4G/5G promoter polymorphism with cardiovascular disease in the elderly. Journal of Thrombosis and Haemostasis : Jth. 1: 1799-804. PMID 12911596 DOI: 10.1046/J.1538-7836.2003.00255.X  0.26
2018 Volpi S, Bult C, Chisholm RL, Deverka PA, Ginsburg GS, Jacob HJ, Kasapi M, McLeod HL, Roden DM, Williams MS, Green ED, Lyman Rodriguez L, Aronson S, Cavallari LH, Denny JC, ... ... Manolio TA, et al. Research directions in the clinical implementation of pharmacogenomics - An Overview of US programs and projects. Clinical Pharmacology and Therapeutics. PMID 29460415 DOI: 10.1002/Cpt.1048  0.257
2013 Wise AL, Gyi L, Manolio TA. eXclusion: toward integrating the X chromosome in genome-wide association analyses. American Journal of Human Genetics. 92: 643-7. PMID 23643377 DOI: 10.1016/J.Ajhg.2013.03.017  0.256
1998 Kuller LH, Shemanski L, Manolio T, Haan M, Fried L, Bryan N, Burke GL, Tracy R, Bhadelia R. Relationship between ApoE, MRI findings, and cognitive function in the Cardiovascular Health Study. Stroke. 29: 388-98. PMID 9472879 DOI: 10.1161/01.Str.29.2.388  0.256
2005 Longstreth WT, Arnold AM, Beauchamp NJ, Manolio TA, Lefkowitz D, Jungreis C, Hirsch CH, O'Leary DH, Furberg CD. Incidence, manifestations, and predictors of worsening white matter on serial cranial magnetic resonance imaging in the elderly: the Cardiovascular Health Study. Stroke; a Journal of Cerebral Circulation. 36: 56-61. PMID 15569873 DOI: 10.1161/01.Str.0000149625.99732.69  0.255
2014 Manolio TA, Murray MF. The growing role of professional societies in educating clinicians in genomics. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 16: 571-2. PMID 24503779 DOI: 10.1038/Gim.2014.6  0.255
1997 Bryan RN, Wells SW, Miller TJ, Elster AD, Jungreis CA, Poirier VC, Lind BK, Manolio TA. Infarctlike lesions in the brain: prevalence and anatomic characteristics at MR imaging of the elderly--data from the Cardiovascular Health Study. Radiology. 202: 47-54. PMID 8988191 DOI: 10.1148/Radiology.202.1.8988191  0.251
1999 Ellsworth DL, Sholinsky P, Jaquish C, Fabsitz RR, Manolio TA. Coronary heart disease: At the interface of molecular genetics and preventive medicine American Journal of Preventive Medicine. 16: 122-133. PMID 10343889 DOI: 10.1016/S0749-3797(98)00138-X  0.25
2024 Lennon NJ, Kottyan LC, Kachulis C, Abul-Husn NS, Arias J, Belbin G, Below JE, Berndt SI, Chung WK, Cimino JJ, Clayton EW, Connolly JJ, Crosslin DR, Dikilitas O, Velez Edwards DR, ... ... Manolio TA, et al. Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations. Nature Medicine. PMID 38374346 DOI: 10.1038/s41591-024-02796-z  0.249
1994 Bryan RN, Manolio TA, Schertz LD, Jungreis C, Poirier VC, Elster AD, Kronmal RA. A method for using MR to evaluate the effects of cardiovascular disease on the brain: the cardiovascular health study. Ajnr. American Journal of Neuroradiology. 15: 1625-33. PMID 7847205  0.248
2001 Miller NH, Schwab DL, Sponseller PD, Manolio TA, Pugh EW, Wilson AP. Characterization of idiopathic scoliosis in a clinically well-defined population Clinical Orthopaedics and Related Research. 349-357. PMID 11716406 DOI: 10.1097/00003086-200111000-00045  0.247
2011 Haas DW, Kuritzkes DR, Ritchie MD, Amur S, Gage BF, Maartens G, Masys D, Fellay J, Phillips E, Ribaudo HJ, Freedberg KA, Petropoulos C, Manolio TA, Gulick RM, Haubrich R, et al. Pharmacogenomics of HIV therapy: summary of a workshop sponsored by the National Institute of Allergy and Infectious Diseases. Hiv Clinical Trials. 12: 277-85. PMID 22180526 DOI: 10.1310/Hct1205-277  0.246
1999 Sempos CT, Bild DE, Manolio TA. Overview of the Jackson Heart Study: A study of cardiovascular diseases in African American men and women American Journal of the Medical Sciences. 317: 142-146. PMID 10100686  0.245
2007 Higgins JP, Little J, Ioannidis JP, Bray MS, Manolio TA, Smeeth L, Sterne JA, Anagnostelis B, Butterworth AS, Danesh J, Dezateux C, Gallacher JE, Gwinn M, Lewis SJ, Minelli C, et al. Turning the pump handle: evolving methods for integrating the evidence on gene-disease association. American Journal of Epidemiology. 166: 863-6. PMID 17804859 DOI: 10.1093/Aje/Kwm248  0.245
1999 Flack JM, Kvasnicka JH, Gardin JM, Gidding SS, Manolio TA, Jacobs DR. Anthropometric and physiologic correlates of mitral valve prolapse in a biethnic cohort of young adults: the CARDIA study. American Heart Journal. 138: 486-92. PMID 10467199 DOI: 10.1016/S0002-8703(99)70151-1  0.245
2000 Anderson RN, Rosenberg HM, Sorlie PD, Thom TJ, Manolio T, Burke GL. The new population standard for age-adjusting death rates. Annals of Epidemiology. 10: 68-9. PMID 10658690 DOI: 10.1016/S1047-2797(99)00054-X  0.244
2021 Satterfield BA, Dikilitas O, Safarova MS, Clarke SL, Tcheandjieu C, Zhu X, Bastarache L, Larson EB, Justice AE, Shang N, Rosenthal EA, Shah A, Namjou-Khales B, Urbina EM, Wei WQ, ... ... Manolio TA, et al. Associations of Genetically Predicted Lipoprotein (a) Levels with Cardiovascular Traits in Individuals of European and African Ancestry. Circulation. Genomic and Precision Medicine. PMID 34282949 DOI: 10.1161/CIRCGEN.120.003354  0.243
2013 Lurie N, Manolio T, Patterson AP, Collins F, Frieden T. Research as a part of public health emergency response. The New England Journal of Medicine. 368: 1251-5. PMID 23534565 DOI: 10.1056/Nejmsb1209510  0.243
2006 Arnar DO, Thorvaldsson S, Manolio TA, Thorgeirsson G, Kristjansson K, Hakonarson H, Stefansson K. Familial aggregation of atrial fibrillation in Iceland. European Heart Journal. 27: 708-12. PMID 16428254 DOI: 10.1093/Eurheartj/Ehi727  0.239
1993 Kronmal RA, Rutan GH, Manolio TA, Borhani NO. Properties of the random zero sphygmomanometer Hypertension. 21: 632-637. PMID 8491498 DOI: 10.1161/01.Hyp.21.5.632  0.238
2021 Glazer AM, Davogustto GE, Shaffer CM, Vanoye CG, Desai RR, Farber-Eger E, Dikilitas O, Shang N, Pacheco JA, Yang T, Muhammad A, Mosley JD, Van Driest SL, Wells QS, Shaffer LL, ... ... Manolio TA, et al. Arrhythmia Variant Associations and Reclassifications in the eMERGE-III Sequencing Study. Circulation. PMID 34930020 DOI: 10.1161/CIRCULATIONAHA.121.055562  0.238
1990 Wagenknecht LE, Perkins LL, Cutter GR, Sidney S, Burke GL, Manolio TA, Jacobs DR, Liu KA, Friedman GD, Hughes GH. Cigarette smoking behavior is strongly related to educational status: the CARDIA study. Preventive Medicine. 19: 158-69. PMID 2193307 DOI: 10.1016/0091-7435(90)90017-E  0.233
2023 Lennon NJ, Kottyan LC, Kachulis C, Abul-Husn N, Arias J, Belbin G, Below JE, Berndt S, Chung W, Cimino JJ, Clayton EW, Connolly JJ, Crosslin D, Dikilitas O, Velez Edwards DR, ... ... Manolio T, et al. Selection, optimization, and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse populations. Medrxiv : the Preprint Server For Health Sciences. PMID 37333246 DOI: 10.1101/2023.05.25.23290535  0.231
2012 Gargis AS, Kalman L, Berry MW, Bick DP, Dimmock DP, Hambuch T, Lu F, Lyon E, Voelkerding KV, Zehnbauer BA, Agarwala R, Bennett SF, Chen B, Chin EL, Compton JG, ... ... Manolio TA, et al. Assuring the quality of next-generation sequencing in clinical laboratory practice. Nature Biotechnology. 30: 1033-6. PMID 23138292 DOI: 10.1038/Nbt.2403  0.23
2005 Axnar D, Thorvaldsson S, Manolio T, Kristjansson K, Kong A, Thorgeirsson G, Hakonarson H, Stefansson K. 133 Evidence of heritability of the common form of atrial fibrillation Ep Europace. 7: 19-19. DOI: 10.1016/Eupace/7.Supplement_1.19-A  0.229
2001 Griffith KA, Sherrill DL, Siegel EM, Manolio TA, Bonekat HW, Enright PL. Predictors of loss of lung function in the elderly: The cardiovascular health study American Journal of Respiratory and Critical Care Medicine. 163: 61-68. PMID 11208627 DOI: 10.1164/Ajrccm.163.1.9906089  0.225
1991 Cutter GR, Burke GL, Dyer AR, Friedman GD, Hilner JE, Hughes GH, Hulley SB, Jacobs DR, Liu K, Manolio TA, Oberman A, Perkins LL, Savage PJ, Serwitz JR, Sidney S, et al. Cardiovascular risk factors in young adults. The CARDIA baseline monograph Controlled Clinical Trials. 12: 1-77. PMID 1851696 DOI: 10.1016/0197-2456(91)90002-4  0.221
2000 Sheifer SE, Gersh BJ, Yanez ND, Ades PA, Burke GL, Manolio TA. Prevalence, predisposing factors, and prognosis of clinically unrecognized myocardial infarction in the elderly Journal of the American College of Cardiology. 35: 119-126. PMID 10636269 DOI: 10.1016/S0735-1097(99)00524-0  0.221
2011 Cheng YC, O'Connell JR, Cole JW, Stine OC, Dueker N, McArdle PF, Sparks MJ, Shen J, Laurie CC, Nelson S, Doheny KF, Ling H, Pugh EW, Brott TG, Brown RD, ... ... Manolio TA, et al. Genome-wide association analysis of ischemic stroke in young adults. G3 (Bethesda, Md.). 1: 505-14. PMID 22384361 DOI: 10.1534/G3.111.001164  0.22
2022 MacArthur JAL, Buniello A, Harris LW, Hayhurst J, McMahon A, Sollis E, Cerezo M, Hall P, Lewis E, Whetzel PL, Bahcall OG, Barroso I, Carroll RJ, Inouye M, Manolio TA, et al. Workshop proceedings: GWAS summary statistics standards and sharing. Cell Genomics. 1. PMID 36082306 DOI: 10.1016/j.xgen.2021.100004  0.218
1992 Manolio TA, Furberg CD. Age as a predictor of outcome: what role does it play? The American Journal of Medicine. 92: 1-6. PMID 1731496 DOI: 10.1016/0002-9343(92)90007-X  0.216
2023 Dikilitas O, Sherafati A, Saadatagah S, Satterfield BA, Kochan DC, Anderson KC, Chung WK, Hebbring SJ, Salvati ZM, Sharp RR, Sturm AC, Gibbs RA, Rowley R, Venner E, Linder JE, ... ... Manolio TA, et al. Familial Hypercholesterolemia in the Electronic Medical Records and Genomics Network: Prevalence, Penetrance, Cardiovascular Risk, and Outcomes After Return of Results. Circulation. Genomic and Precision Medicine. 16: e003816. PMID 37071725 DOI: 10.1161/CIRCGEN.122.003816  0.213
1991 O'Leary DH, Polak JF, Wolfson SK, Bond MG, Bommer W, Sheth S, Psaty BM, Sharrett AR, Manolio TA. Use of sonography to evaluate carotid atherosclerosis in the elderly. The Cardiovascular Health Study. CHS Collaborative Research Group. Stroke; a Journal of Cerebral Circulation. 22: 1155-63. PMID 1926258 DOI: 10.1161/01.STR.22.9.1155  0.21
2023 Linder JE, Allworth A, Bland ST, Caraballo PJ, Chisholm RL, Clayton EW, Crosslin DR, Dikilitas O, DiVietro A, Esplin ED, Forman S, Freimuth RR, Gordon AS, Green R, Harden MV, ... ... Manolio TA, et al. Returning integrated genomic risk and clinical recommendations: the eMERGE study. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 100006. PMID 36621880 DOI: 10.1016/j.gim.2023.100006  0.207
1996 Enright PL, Kronmal RA, Smith VE, Gardin JM, Schenker MB, Manolio TA. Reduced vital capacity in elderly persons with hypertension, coronary heart disease, or left ventricular hypertrophy. the Cardiovascular Health Study Pneumologie. 50: 444.  0.207
1998 Kronmal RA, Hart RG, Manolio TA, Talbert RL, Beauchamp NJ, Newman A. Aspirin use and incident stroke in the Cardiovascular Health Study Stroke. 29. PMID 9596230 DOI: 10.1161/01.Str.29.5.887  0.206
1992 Ettinger WH, Wahl PW, Kuller LH, Bush TL, Tracy RP, Manolio TA, Borhani NO, Wong ND, O'Leary DH. Lipoprotein lipids in older people. Results from the Cardiovascular Health Study. The CHS Collaborative Research Group. Circulation. 86: 858-69. PMID 1516198 DOI: 10.1161/01.CIR.86.3.858  0.203
2007 Seminara D, Khoury MJ, O'Brien TR, Manolio T, Gwinn ML, Little J, Higgins JP, Bernstein JL, Boffetta P, Bondy M, Bray MS, Brenchley PE, Buffler PA, Casas JP, Chokkalingam AP, et al. The emergence of networks in human genome epidemiology: challenges and opportunities. Epidemiology (Cambridge, Mass.). 18: 1-8. PMID 17179752 DOI: 10.1097/01.Ede.0000249540.17855.B7  0.203
1989 Manolio TA, Beattie C, Christopherson R, Pearson TA. Regional versus general anesthesia in high-risk surgical patients: the need for a clinical trial. Journal of Clinical Anesthesia. 1: 414-21. PMID 2624749 DOI: 10.1016/0952-8180(89)90003-2  0.202
2020 Green ED, Gunter C, Biesecker LG, Di Francesco V, Easter CL, Feingold EA, Felsenfeld AL, Kaufman DJ, Ostrander EA, Pavan WJ, Phillippy AM, Wise AL, Dayal JG, Kish BJ, Mandich A, ... ... Manolio TA, et al. Strategic vision for improving human health at The Forefront of Genomics. Nature. 586: 683-692. PMID 33116284 DOI: 10.1038/s41586-020-2817-4  0.201
2022 Haga SB, Chung WK, Cubano LA, Curry TB, Empey PE, Ginsburg GS, Mangold K, Miyake CY, Prakash SK, Ramsey LB, Rowley R, Rohrer Vitek CR, Skaar TC, Wynn J, Manolio TA. Development of Competency-based Online Genomic Medicine Training (COGENT). Personalized Medicine. PMID 36416152 DOI: 10.2217/pme-2022-0101  0.199
2022 Wiley K, Findley L, Goldrich M, Rakhra-Burris TK, Stevens A, Williams P, Bult CJ, Chisholm R, Deverka P, Ginsburg GS, Green ED, Jarvik G, Mensah GA, Ramos E, Relling MV, ... ... Manolio TA, et al. A research agenda to support the development and implementation of genomics-based clinical informatics tools and resources. Journal of the American Medical Informatics Association : Jamia. PMID 35485600 DOI: 10.1093/jamia/ocac057  0.195
1985 Gardner TJ, Horneffer PJ, Manolio TA, Pearson TA, Gott VL, Baumgartner WA, Borkon AM, Watkins L, Reitz BA. Stroke following coronary artery bypass grafting: a ten-year study. The Annals of Thoracic Surgery. 40: 574-81. PMID 3878134 DOI: 10.1016/S0003-4975(10)60352-9  0.194
2007 Cao JJ, Arnold AM, Manolio TA, Polak JF, Psaty BM, Hirsch CH, Kuller LH, Cushman M. Association of carotid artery intima-media thickness, plaques, and C-reactive protein with future cardiovascular disease and all-cause mortality: the Cardiovascular Health Study. Circulation. 116: 32-8. PMID 17576871 DOI: 10.1161/Circulationaha.106.645606  0.194
1997 Sacco RL, Benjamin EJ, Broderick JP, Dyken M, Easton JD, Feinberg WM, Goldstein LB, Gorelick PB, Howard G, Kittner SJ, Manolio TA, Whisnant JP, Wolf PA. American Heart Association Prevention Conference. IV. Prevention and Rehabilitation of Stroke. Risk factors. Stroke; a Journal of Cerebral Circulation. 28: 1507-17. PMID 9227708 DOI: 10.1161/01.str.28.7.1507  0.187
2006 Dennis B, Aziz K, She L, Faruqui AM, Davis CE, Manolio TA, Burke GL, Aziz Su. High rates of obesity and cardiovascular disease risk factors in lower middle class community in Pakistan: the Metroville Health Study. Jpma. the Journal of the Pakistan Medical Association. 56: 267-72. PMID 16827250  0.182
2016 Wise AL, Manolio TA. Public and Population Health Genomics Medical and Health Genomics. 311-318. DOI: 10.1016/B978-0-12-420196-5.00023-X  0.18
2000 Rywik SL, Williams OD, Pajak A, Broda G, Davis CE, Kawalec E, Manolio TA, Piotrowski W, Hutchinson R. Incidence and correlates of hypertension in the Atherosclerosis Risk in Communities (ARIC) study and the Monitoring Trends and Determinants of Cardiovascular Disease (POL-MONICA) project. Journal of Hypertension. 18: 999-1006. PMID 10953989  0.18
2021 Johnston JJ, Brennan ML, Radenbaugh B, Yoo SJ, Hernandez SM, Lewis KL, Katz AE, Manolio TA, Biesecker LG. The ACMG SF v3.0 gene list increases returnable variant detection by 22% when compared with v2.0 in the ClinSeq cohort. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 34906458 DOI: 10.1016/j.gim.2021.11.012  0.178
1996 Enright PL, Arnold A, Manolio TA, Kuller LH, Kronmal RA. Sporometry Reference Values for Healthy Elderly Blacks Chest. 110: 1416-1424. PMID 8989054  0.175
1994 Furberg CD, Berglund G, Manolio TA, Psaty BM. Overtreatment and undertreatment of hypertension Journal of Internal Medicine. 235: 387-397. PMID 8182392 DOI: 10.1111/J.1365-2796.1994.Tb01093.X  0.173
1992 Orden SR, Dyer AR, Liu K, Perkins L, Ruth KJ, Burke G, Manolio TA. Random digit dialing in Chicago CARDIA: comparison of individuals with unlisted and listed telephone numbers. American Journal of Epidemiology. 135: 697-709. PMID 1580246 DOI: 10.1093/oxfordjournals.aje.a116349  0.17
2008 Manolio TA. Biorepositories--at the bleeding edge. International Journal of Epidemiology. 37: 231-3. PMID 18381397 DOI: 10.1093/Ije/Dym282  0.169
2001 Newman AB, Arnold AM, Burke GL, O'Leary DH, Manolio TA, Fisicaro M. Cardiovascular disease and mortality in older adults with small abdominal aortic aneurysm detected by ultrasonography. The Cardiovascular Health Study Italian Heart Journal Supplement. 2: 685-686. PMID 11460846  0.169
2016 Manolio TA, Ward R, Ginsburg GS. Clinical implementation of genomic medicine: the importance of global collaboration Expert Review of Precision Medicine and Drug Development. 1: 349-351. DOI: 10.1080/23808993.2016.1192460  0.168
1992 Manolio TA, Burke GL, Savage PJ, Jacobs DR, Sidney S, Wagenknecht LE, Allman RM, Tracy RP. Sex- and Race-Related Differences in Liver-Associated Serum Chemistry Tests in Young Adults in the Cardia Study Clinical Chemistry. 38: 1853-1859. DOI: 10.1093/clinchem/38.9.1853  0.167
2013 Manolio TA, Chisholm RL, Ozenberger B, Roden DM, Williams MS, Wilson R, Bick D, Bottinger EP, Brilliant MH, Eng C, Frazer KA, Korf B, Ledbetter DH, Lupski JR, Marsh C, et al. Implementing Genomic Medicine in the Clinic Obstetrical & Gynecological Survey. 68: 621-623. DOI: 10.1097/01.ogx.0000435523.89711.77  0.163
1996 Rautaharju PM, Manolio TA, Siscovick D, Zhou SH, Gardin JM, Furberg CD, Borhani NO, Newman A. Classification Accuracy of Electrocardiographic Criteria for Left Ventricular Hypertrophy in Normal Weight and Overweight Older Adults: The Cardiovascular Health Study Annals of Noninvasive Electrocardiology. 1: 121-132.  0.153
1986 Gardner TJ, Horneffer PJ, Manolio TA, Hoff SJ, Pearson TA. Major stroke after coronary artery bypass surgery: changing magnitude of the problem. Journal of Vascular Surgery. 3: 684-7. PMID 3485725 DOI: 10.1016/0741-5214(86)90308-3  0.152
1993 Manolio TA, Harlan WR. Research on coronary disease in women: political or scientific imperative? British Heart Journal. 69: 1-2. PMID 8457386 DOI: 10.1136/hrt.69.1.1  0.15
2001 Longstreth W.T. J, Diehr P, Manolio TA, Beauchamp NJ, Jungreis CA, Lefkowitz D. Cluster analysis and patterns of findings on cranial magnetic resonance imaging of the elderly: The cardiovascular health study Archives of Neurology. 58: 635-640. PMID 11295995 DOI: 10.1001/Archneur.58.4.635  0.149
1995 Gidding SS, Xie X, Liu K, Manolio T, Flack JM, Gardin JM. Cardiac function in smokers and nonsmokers: the CARDIA study. The Coronary Artery Risk Development in Young Adults Study. Journal of the American College of Cardiology. 26: 211-6. PMID 7797754 DOI: 10.1016/0735-1097(95)00118-J  0.147
2023 Manolio TA, Narula J, Bult CJ, Chisholm RL, Deverka PA, Ginsburg GS, Green ED, Hooker G, Jarvik GP, Mensah GA, Ramos EM, Roden DM, Rowley R, Williams MS. Genomic medicine year in review: 2023. American Journal of Human Genetics. 110: 1992-1995. PMID 38065071 DOI: 10.1016/j.ajhg.2023.11.001  0.146
2022 Manolio TA, Narula J, Bult CJ, Chisholm RL, Deverka PA, Ginsburg GS, Goldrich M, Green ED, Jarvik GP, Mensah GA, Ramos EM, Relling MV, Roden DM, Rowley R, Williams MS. Genomic Medicine Year in Review: 2022. American Journal of Human Genetics. 109: 2101-2104. PMID 36459977 DOI: 10.1016/j.ajhg.2022.11.003  0.146
2021 Manolio TA, Bult CJ, Chisholm RL, Deverka PA, Ginsburg GS, Goldrich M, Jarvik GP, Mensah GA, Ramos EM, Relling MV, Roden DM, Rowley R, Williams MS, Green ED. Genomic medicine year in review: 2021. American Journal of Human Genetics. 108: 2210-2214. PMID 34861172 DOI: 10.1016/j.ajhg.2021.11.006  0.146
2020 Manolio TA, Bult CJ, Chisholm RL, Deverka PA, Ginsburg GS, Goldrich M, Jarvik GP, Mensah GA, Relling MV, Roden DM, Rowley R, Tamburro C, Williams MS, Green ED. Genomic Medicine Year in Review: 2020. American Journal of Human Genetics. 107: 1007-1010. PMID 33275910 DOI: 10.1016/j.ajhg.2020.11.005  0.146
1994 Manolio TA, Burke GL, Savage PJ, Sidney S, Gardin JM, Oberman A. Exercise blood pressure response and 5-year risk of elevated blood pressure in a cohort of young adults: the CARDIA study. American Journal of Hypertension. 7: 234-41. PMID 8003274 DOI: 10.1093/ajh/7.3.234  0.146
2021 Khan SS, Hoell C, Castillo LM, Connolly JJ, Crosslin DR, Chung WK, Gordon AS, Harr M, Jarvik GP, Kullo I, Larson EB, Leppig KA, Manolio T, Pacheco JA, Ralston JD, et al. Practice Patterns After Return of Rare Variants Associated With Cardiomyopathy in the Electronic Medical Records and Genomics Network. Circulation. Heart Failure. CIRCHEARTFAILURE1200. PMID 33951936 DOI: 10.1161/CIRCHEARTFAILURE.120.008155  0.146
2023 Linder JE, Tao R, Chung WK, Kiryluk K, Liu C, Weng C, Connolly JJ, Hakonarson H, Harr M, Leppig KA, Jarvik GP, Veenstra DL, Aufox S, Chisholm RL, Gordon AS, ... ... Manolio TA, et al. Prospective, multi-site study of healthcare utilization after actionable monogenic findings from clinical sequencing. American Journal of Human Genetics. PMID 37883979 DOI: 10.1016/j.ajhg.2023.10.006  0.146
2007 Feero WG, Manolio TA, Guttmacher AE, Collins FS. Validity of reported genetic risk factors for acute coronary syndrome. Jama. 298: 1757; author reply 1. PMID 17940226 DOI: 10.1001/jama.298.15.1757-a  0.14
1990 Wagenknecht LE, Cutter GR, Haley NJ, Sidney S, Manolio TA, Hughes GH, Jacobs DR. Racial differences in serum cotinine levels among smokers in the Coronary Artery Risk Development in (Young) Adults study. American Journal of Public Health. 80: 1053-6. PMID 2382740 DOI: 10.2105/AJPH.80.9.1053  0.133
2021 Liu C, Zeinomar N, Chung WK, Kiryluk K, Gharavi AG, Hripcsak G, Crew KD, Shang N, Khan A, Fasel D, Manolio TA, Jarvik GP, Rowley R, Justice AE, Rahm AK, et al. Generalizability of Polygenic Risk Scores for Breast Cancer Among Women With European, African, and Latinx Ancestry. Jama Network Open. 4: e2119084. PMID 34347061 DOI: 10.1001/jamanetworkopen.2021.19084  0.132
2023 Sun L, Wang Z, Lu T, Manolio TA, Paterson AD. eXclusionarY: 10 years later, where are the sex chromosomes in GWASs? American Journal of Human Genetics. 110: 903-912. PMID 37267899 DOI: 10.1016/j.ajhg.2023.04.009  0.129
2021 Biesecker LG, Green ED, Manolio T, Solomon BD, Curtis D. Should all babies have their genome sequenced at birth? Bmj (Clinical Research Ed.). 375: n2679. PMID 34789511 DOI: 10.1136/bmj.n2679  0.125
2003 Aziz KU, Dennis B, Davis CE, Sun K, Burke G, Manolio T, Faruqui AM, Chagani H, Ashraf T, Patel N, Jafery H, Ghauri S, Faisal M, Tareen AK. Efficacy of CVD risk factor modification in a lower-middle class community in Pakistan: the Metroville Health Study. Asia-Pacific Journal of Public Health / Asia-Pacific Academic Consortium For Public Health. 15: 30-6. PMID 14620495 DOI: 10.1177/101053950301500106  0.124
2003 Manolio TA, Olson J, Longstreth WT. Hypertension and cognitive function: Pathophysiologic effects of hypertension on the brain Current Hypertension Reports. 5: 255-261. PMID 12724059 DOI: 10.1007/S11906-003-0029-6  0.123
2003 Longstreth WT, Dulberg C, Manolio TA. White matter changes, creatinine, age, and ankle arm index predicted incident MRI defined infarctions in older adults Evidence-Based Medicine. 8: 121. DOI: 10.1136/Ebm.8.4.121  0.122
2012 Ding K, Shameer K, Jouni H, Masys DR, Jarvik GP, Kho AN, Ritchie MD, McCarty CA, Chute CG, Manolio TA, Kullo IJ. Genetic Loci implicated in erythroid differentiation and cell cycle regulation are associated with red blood cell traits. Mayo Clinic Proceedings. 87: 461-74. PMID 22560525 DOI: 10.1016/j.mayocp.2012.01.016  0.117
2007 Campbell H, Manolio T. Commentary: rare alleles, modest genetic effects and the need for collaboration. International Journal of Epidemiology. 36: 445-8. PMID 17470492 DOI: 10.1093/IJE/DYM055  0.116
1992 Burke GL, Savage PJ, Manolio TA, Sprafka JM, Wagenknecht LE, Sidney S, Perkins LL, Liu K, Jacobs DR. Correlates of obesity in young black and white women: the CARDIA Study. American Journal of Public Health. 82: 1621-5. PMID 1456336 DOI: 10.2105/AJPH.82.12.1621  0.111
2022 Sherafati A, Elsekaily O, Saadatagah S, Kochan DC, Lee C, Wiesner GL, Liu C, Dellefave-Castillo L, Namjou B, Perez EF, Salvati ZM, Connolly JJ, Hakonarson H, Williams MS, Jarvik GP, ... ... Manolio TA, et al. Pathogenic variants in arteriopathy genes detected in a targeted sequencing study: Penetrance and 1-year outcomes after return of results. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 35943490 DOI: 10.1016/j.gim.2022.07.007  0.11
1990 Horneffer PJ, Zahka KG, Rowe SA, Manolio TA, Gott VL, Reitz BA, Gardner TJ. Long-term results of total repair of tetralogy of Fallot in childhood. The Annals of Thoracic Surgery. 50: 179-83; discussion 1. PMID 2383102 DOI: 10.1016/0003-4975(90)90728-O  0.11
1989 Zahka KG, Manolio TA, Rykiel MJ, Abel DL, Neill CA, Kidd L. Handgrip strength after the Blalock-Taussig shunt: 14 to 34 year follow-up. Clinical Cardiology. 11: 627-9. PMID 2465859 DOI: 10.1002/clc.4960110907  0.109
2003 Cao J, Thach C, Manolio T. C-reactive protein, carotid intima-media thickness, and incidence of ischemic stroke in the elderly Acc Current Journal Review. 12: 24-25. DOI: 10.1016/j.accreview.2003.09.013  0.097
2020 Manolio TA, Goodhand P, Ginsburg G. The International Hundred Thousand Plus Cohort Consortium: integrating large-scale cohorts to address global scientific challenges. The Lancet. Digital Health. 2: e567-e568. PMID 33103095 DOI: 10.1016/S2589-7500(20)30242-9  0.095
2001 Longstreth W.T. J, Diehr P, Beauchamp NJ, Manolio TA. Patterns on cranial magnetic resonance imaging in elderly people and vascular disease outcomes Archives of Neurology. 58: 2074. PMID 11735783 DOI: 10.1001/Archneur.58.12.2074  0.095
2006 Geller NL, Sorlie P, Coady S, Fleg J, Manolio T, Friedman L. Clinical trials and epidemiological studies. Clinical Trials (London, England). 2: 538. PMID 16422314 DOI: 10.1191/1740774505CN124XX  0.09
1993 Wagenknecht LE, Manolio TA, Sidney S, Burke GL, Haley NJ. Environmental tobacco smoke exposure as determined by cotinine in black and white young adults: The CARDIA study Environmental Research. 63: 39-46. PMID 8404773 DOI: 10.1006/enrs.1993.1124  0.09
2023 Rider RA, Cubano L, Madden EB, Rowley RK, Manolio TA. Survey of the training needs of genetic assistants supports the creation of genetic assistant training programs. Journal of Genetic Counseling. PMID 37655513 DOI: 10.1002/jgc4.1780  0.081
2007 Guralnik JM, Manolio TA. Design and conduct of observational studies and clinical trials Principles and Practice of Clinical Research. 197-217. DOI: 10.1016/B978-012369440-9/50020-7  0.076
1988 Manolio TA, Fishel SC, Beattie C, Torres J, Christopherson R, Merritt WT, Whelton PK. Evaluation of the Dinamap continuous blood pressure monitor. American Journal of Hypertension. 1: 161S-167S. PMID 3415794 DOI: 10.1093/ajh/1.3.161S  0.076
1988 Yaster M, Buck JR, Dudgeon DL, Manolio TA, Simmons RS, Zeller P, Haller JA. Hemodynamic effects of primary closure of omphalocele/gastroschisis in human newborns. Anesthesiology. 69: 84-8. PMID 2968772 DOI: 10.1097/00000542-198807000-00012  0.073
1991 Rowe SA, Zahka KG, Manolio TA, Horneffer PJ, Kidd L. Lung function and pulmonary regurgitation limit exercise capacity in postoperative tetralogy of Fallot. Journal of the American College of Cardiology. 17: 461-6. PMID 1991905 DOI: 10.1016/S0735-1097(10)80116-0  0.065
1993 Wagenknecht LE, Manolio TA, Lewis CE, Perkins LL, Lando HA, Hulley SB. Race and education in relation to stopping smoking in the US: the CARDIA study Tobacco Control. 2: 286-292. DOI: 10.1136/tc.2.4.286  0.053
1991 Spear RM, Yaster M, Berkowitz ID, Maxwell LG, Bender KS, Naclerio R, Manolio TA, Nichols DG. Preinduction of anesthesia in children with rectally administered midazolam Anesthesiology. 74: 670-674. PMID 2008948 DOI: 10.1097/00000542-199104000-00009  0.05
2017 Safarova M, Austin E, de Andrade M, Bastarache L, Ye Z, Zheng N, Schaid D, Williams M, Ritchie M, Borthwick K, Larson E, Scrol A, Jarvik G, Manolio T, Hebbring S, et al. SCANNING THE PHENOME TO UNCOVER PLEIOTROPIC EFFECTS OF PCSK9 Journal of the American College of Cardiology. 69: 2561. DOI: 10.1016/S0735-1097(17)35950-8  0.036
1981 Rogol AD, Eastman RC, Manolio T, Rosen SW. Unusual heterogeneity of circulating prolactin in an acromegalic. Journal of Endocrinological Investigation. 4: 221-7. PMID 6792266 DOI: 10.1007/BF03350457  0.028
2010 Manolio TA. The author replies New England Journal of Medicine. 363: 2077.  0.015
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