| Year |
Citation |
Score |
| 2022 |
Li N, Rana TM. Regulation of antiviral innate immunity by chemical modification of viral RNA. Wiley Interdisciplinary Reviews. Rna. e1720. PMID 35150188 DOI: 10.1002/wrna.1720 |
0.385 |
|
| 2021 |
Li N, Rana T. Detection of N6-methyladenosine in SARS-CoV-2 RNA by methylated RNA immunoprecipitation sequencing (MeRIP-Seq). Star Protocols. 101067. PMID 34901888 DOI: 10.1016/j.xpro.2021.101067 |
0.349 |
|
| 2021 |
Zhang Q, Kang Y, Wang S, Gonzalez GM, Li W, Hui H, Wang Y, Rana TM. HIV reprograms host mAm RNA methylome by viral Vpr protein-mediated degradation of PCIF1. Nature Communications. 12: 5543. PMID 34545078 DOI: 10.1038/s41467-021-25683-4 |
0.381 |
|
| 2021 |
Huff S, Tiwari SK, Gonzalez GM, Wang Y, Rana TM. mA-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells. Acs Chemical Biology. PMID 33412003 DOI: 10.1021/acschembio.0c00841 |
0.351 |
|
| 2020 |
Wang S, Zhang Q, Hui H, Agrawal K, Karris MAY, Rana TM. An Atlas of Immune Cell Exhaustion in HIV-Infected Individuals Revealed by Single-Cell Transcriptomics. Emerging Microbes & Infections. 1-77. PMID 32954948 DOI: 10.1080/22221751.2020.1826361 |
0.362 |
|
| 2020 |
Dang J, Tiwari SK, Agrawal K, Hui H, Qin Y, Rana TM. Glial cell diversity and methamphetamine-induced neuroinflammation in human cerebral organoids. Molecular Psychiatry. PMID 32051547 DOI: 10.1038/S41380-020-0676-X |
0.356 |
|
| 2020 |
Wang S, Zhang Q, Tiwari SK, Lichinchi G, Yau EH, Hui H, Li W, Furnari F, Rana TM. Integrin αvβ5 Internalizes Zika Virus during Neural Stem Cells Infection and Provides a Promising Target for Antiviral Therapy. Cell Reports. PMID 31956073 DOI: 10.1016/J.Celrep.2019.11.020 |
0.311 |
|
| 2019 |
Chao TC, Zhang Q, Li Z, Tiwari SK, Qin Y, Yau E, Sanchez A, Singh G, Chang K, Kaul M, Karris MAY, Rana TM. The Long Noncoding RNA Regulates HIV-1 Replication through Epigenetic Regulation of the HIV-1 Promoter. Mbio. 10. PMID 31551335 DOI: 10.1128/Mbio.02016-19 |
0.459 |
|
| 2019 |
Dang JW, Tiwari SK, Qin Y, Rana TM. Genome-wide Integrative Analysis of Zika-Virus-Infected Neuronal Stem Cells Reveals Roles for MicroRNAs in Cell Cycle and Stemness. Cell Reports. 27: 3618-3628.e5. PMID 31216479 DOI: 10.1016/J.Celrep.2019.05.059 |
0.328 |
|
| 2019 |
Zhang Q, Chao TC, Patil VS, Qin Y, Tiwari SK, Chiou J, Dobin A, Tsai CM, Li Z, Dang J, Gupta S, Urdahl K, Nizet V, Gingeras TR, Gaulton KJ, ... Rana TM, et al. The long noncoding RNA regulates inflammatory gene expression. The Embo Journal. PMID 30918008 DOI: 10.15252/Embj.2018100041 |
0.369 |
|
| 2019 |
Sharkey M, Sharova N, Mohammed I, Huff SE, Kummetha IR, Singh G, Rana TM, Stevenson M. HIV-1 Escape from Small-Molecule Antagonism of Vif. Mbio. 10. PMID 30808702 DOI: 10.1128/Mbio.00144-19 |
0.411 |
|
| 2019 |
Lichinchi G, Rana TM. Profiling of N-Methyladenosine in Zika Virus RNA and Host Cellular mRNA. Methods in Molecular Biology (Clifton, N.J.). 1870: 209-218. PMID 30539558 DOI: 10.1007/978-1-4939-8808-2_16 |
0.434 |
|
| 2017 |
Rana TM, Yau EH, Kummetha IR, Lichinchi G, Tang R, Zhang Y. Genome-wide CRISPR screen for essential cell growth mediators in mutant KRAS colorectal cancers. Cancer Research. PMID 28954733 DOI: 10.1158/0008-5472.Can-17-2043 |
0.306 |
|
| 2017 |
Tiwari SK, Dang J, Qin Y, Lichinchi G, Bansal V, Rana TM. Zika virus infection reprograms global transcription of host cells to allow sustained infection. Emerging Microbes & Infections. 6: e24. PMID 28442752 DOI: 10.1038/Emi.2017.9 |
0.329 |
|
| 2016 |
Gong D, Kim YH, Xiao Y, Du Y, Xie Y, Lee KK, Feng J, Farhat N, Zhao D, Shu S, Dai X, Chanda SK, Rana TM, Krogan NJ, Sun R, et al. A Herpesvirus Protein Selectively Inhibits Cellular mRNA Nuclear Export. Cell Host & Microbe. 20: 642-653. PMID 27832591 DOI: 10.1016/J.Chom.2016.10.004 |
0.415 |
|
| 2016 |
Lichinchi G, Zhao BS, Wu Y, Lu Z, Qin Y, He C, Rana TM. Dynamics of Human and Viral RNA Methylation during Zika Virus Infection. Cell Host & Microbe. PMID 27773536 DOI: 10.1016/J.Chom.2016.10.002 |
0.451 |
|
| 2016 |
Lichinchi G, Gao S, Saletore Y, Gonzalez GM, Bansal V, Wang Y, Mason CE, Rana TM. Dynamics of the human and viral m(6)A RNA methylomes during HIV-1 infection of T cells. Nature Microbiology. 1: 16011. PMID 27572442 DOI: 10.1038/Nmicrobiol.2016.11 |
0.475 |
|
| 2016 |
Mohammed I, Kummetha IR, Singh G, Sharova N, Lichinchi G, Dang J, Stevenson M, Rana TM. 1,2,3-Triazoles as Amide Bioisosteres: Discovery of a New Class of Potent HIV-1 Vif Antagonists. Journal of Medicinal Chemistry. PMID 27509004 DOI: 10.1021/Acs.Jmedchem.6B00247 |
0.313 |
|
| 2016 |
Yang CS, Chang KY, Dang J, Rana TM. Polycomb Group Protein Pcgf6 Acts as a Master Regulator to Maintain Embryonic Stem Cell Identity. Scientific Reports. 6: 26899. PMID 27247273 DOI: 10.1038/Srep26899 |
0.34 |
|
| 2016 |
Sansó M, Levin RS, Lipp JJ, Wang VY, Greifenberg AK, Quezada EM, Ali A, Ghosh A, Larochelle S, Rana TM, Geyer M, Tong L, Shokat KM, Fisher RP. P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates. Genes & Development. 30: 117-31. PMID 26728557 DOI: 10.1101/Gad.269589.115 |
0.453 |
|
| 2016 |
Stevenson M, Rana T. F-101 Pharmacologic inhibition of the HIV-1 vif Jaids Journal of Acquired Immune Deficiency Syndromes. 71: 60. DOI: 10.1097/01.Qai.0000479624.32397.E6 |
0.32 |
|
| 2015 |
Lin N, Dang J, Rana TM. Haunting the HOXA Locus: Two Faces of lncRNA Regulation. Cell Stem Cell. 16: 449-50. PMID 25957895 DOI: 10.1016/J.Stem.2015.04.010 |
0.401 |
|
| 2015 |
McCarroll JA, Dwarte T, Baigude H, Dang J, Yang L, Erlich RB, Kimpton K, Teo J, Sagnella SM, Akerfeldt MC, Liu J, Phillips PA, Rana TM, Kavallaris M. Therapeutic targeting of polo-like kinase 1 using RNA-interfering nanoparticles (iNOPs) for the treatment of non-small cell lung cancer. Oncotarget. 6: 12020-34. PMID 25557168 DOI: 10.18632/Oncotarget.2664 |
0.337 |
|
| 2015 |
Han J, Cai J, Borjihan W, Ganbold T, Rana TM, Baigude H. Preparation of novel curdlan nanoparticles for intracellular siRNA delivery. Carbohydrate Polymers. 117: 324-30. PMID 25498642 DOI: 10.1016/J.Carbpol.2014.09.069 |
0.404 |
|
| 2014 |
Baigude H, Rana TM. Strategies to antagonize miRNA functions in vitro and in vivo. Nanomedicine (London, England). 9: 2545-55. PMID 25490425 DOI: 10.2217/Nnm.14.162 |
0.301 |
|
| 2014 |
Li Z, Rana TM. Decoding the noncoding: prospective of lncRNA-mediated innate immune regulation. Rna Biology. 11: 979-85. PMID 25482890 DOI: 10.4161/Rna.29937 |
0.41 |
|
| 2014 |
Li Z, Dang J, Chang KY, Rana TM. MicroRNA-mediated regulation of extracellular matrix formation modulates somatic cell reprogramming. Rna (New York, N.Y.). 20: 1900-15. PMID 25336587 DOI: 10.1261/Rna.043745.113 |
0.366 |
|
| 2014 |
Yang CS, Chang KY, Rana TM. Genome-wide functional analysis reveals factors needed at the transition steps of induced reprogramming. Cell Reports. 8: 327-37. PMID 25043178 DOI: 10.1016/J.Celrep.2014.07.002 |
0.307 |
|
| 2014 |
Li Z, Rana TM. Therapeutic targeting of microRNAs: current status and future challenges. Nature Reviews. Drug Discovery. 13: 622-38. PMID 25011539 DOI: 10.1038/Nrd4359 |
0.326 |
|
| 2014 |
Sakurai K, Talukdar I, Patil VS, Dang J, Li Z, Chang KY, Lu CC, Delorme-Walker V, Dermardirossian C, Anderson K, Hanein D, Yang CS, Wu D, Liu Y, Rana TM. Kinome-wide functional analysis highlights the role of cytoskeletal remodeling in somatic cell reprogramming. Cell Stem Cell. 14: 523-34. PMID 24702998 DOI: 10.1016/J.Stem.2014.03.001 |
0.355 |
|
| 2014 |
Lin N, Chang KY, Li Z, Gates K, Rana ZA, Dang J, Zhang D, Han T, Yang CS, Cunningham TJ, Head SR, Duester G, Dong PD, Rana TM. An evolutionarily conserved long noncoding RNA TUNA controls pluripotency and neural lineage commitment. Molecular Cell. 53: 1005-19. PMID 24530304 DOI: 10.1016/J.Molcel.2014.01.021 |
0.424 |
|
| 2014 |
Li Z, Chao TC, Chang KY, Lin N, Patil VS, Shimizu C, Head SR, Burns JC, Rana TM. The long noncoding RNA THRIL regulates TNFα expression through its interaction with hnRNPL. Proceedings of the National Academy of Sciences of the United States of America. 111: 1002-7. PMID 24371310 DOI: 10.1073/Pnas.1313768111 |
0.381 |
|
| 2014 |
Patil VS, Zhou R, Rana TM. Gene regulation by non-coding RNAs. Critical Reviews in Biochemistry and Molecular Biology. 49: 16-32. PMID 24164576 DOI: 10.3109/10409238.2013.844092 |
0.46 |
|
| 2013 |
Baigude H, Su J, McCarroll J, Rana TM. In Vivo Delivery of RNAi by Reducible Interfering Nanoparticles (iNOPs). Acs Medicinal Chemistry Letters. 4: 720-723. PMID 24319542 DOI: 10.1021/Ml4001003 |
0.423 |
|
| 2013 |
Xiong XP, Kurthkoti K, Chang KY, Lichinchi G, De N, Schneemann A, MacRae IJ, Rana TM, Perrimon N, Zhou R. Core small nuclear ribonucleoprotein particle splicing factor SmD1 modulates RNA interference in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 110: 16520-5. PMID 24067655 DOI: 10.1073/Pnas.1315803110 |
0.484 |
|
| 2013 |
Nalam MN, Ali A, Reddy GS, Cao H, Anjum SG, Altman MD, Yilmaz NK, Tidor B, Rana TM, Schiffer CA. Substrate envelope-designed potent HIV-1 protease inhibitors to avoid drug resistance. Chemistry & Biology. 20: 1116-24. PMID 24012370 DOI: 10.1016/J.Chembiol.2013.07.014 |
0.329 |
|
| 2013 |
Zhou R, Rana TM. RNA-based mechanisms regulating host-virus interactions. Immunological Reviews. 253: 97-111. PMID 23550641 DOI: 10.1111/Imr.12053 |
0.503 |
|
| 2012 |
Mohammed I, Parai MK, Jiang X, Sharova N, Singh G, Stevenson M, Rana TM. SAR and Lead Optimization of an HIV-1 Vif-APOBEC3G Axis Inhibitor. Acs Medicinal Chemistry Letters. 3: 465-469. PMID 24533175 DOI: 10.1021/Ml300037K |
0.327 |
|
| 2012 |
Li Z, Rana TM. A kinase inhibitor screen identifies small-molecule enhancers of reprogramming and iPS cell generation. Nature Communications. 3: 1085. PMID 23011139 DOI: 10.1038/Ncomms2059 |
0.324 |
|
| 2012 |
Parai MK, Huggins DJ, Cao H, Nalam MN, Ali A, Schiffer CA, Tidor B, Rana TM. Design, synthesis, and biological and structural evaluations of novel HIV-1 protease inhibitors to combat drug resistance. Journal of Medicinal Chemistry. 55: 6328-41. PMID 22708897 DOI: 10.1021/Jm300238H |
0.366 |
|
| 2012 |
Baigude H, Rana TM. Interfering nanoparticles for silencing microRNAs. Methods in Enzymology. 509: 339-53. PMID 22568914 DOI: 10.1016/B978-0-12-391858-1.00017-4 |
0.332 |
|
| 2012 |
Baigude H, Ahsanullah, Li Z, Zhou Y, Rana TM. miR-TRAP: a benchtop chemical biology strategy to identify microRNA targets. Angewandte Chemie (International Ed. in English). 51: 5880-3. PMID 22566243 DOI: 10.1002/Anie.201201512 |
0.404 |
|
| 2012 |
Ali A, Wang J, Nathans RS, Cao H, Sharova N, Stevenson M, Rana TM. Synthesis and structure-activity relationship studies of HIV-1 virion infectivity factor (Vif) inhibitors that block viral replication. Chemmedchem. 7: 1217-29. PMID 22555953 DOI: 10.1002/Cmdc.201200079 |
0.417 |
|
| 2012 |
Zhou H, Arcila ML, Li Z, Lee EJ, Henzler C, Liu J, Rana TM, Kosik KS. Deep annotation of mouse iso-miR and iso-moR variation. Nucleic Acids Research. 40: 5864-75. PMID 22434881 DOI: 10.1093/Nar/Gks247 |
0.356 |
|
| 2012 |
Li Z, Rana TM. Molecular mechanisms of RNA-triggered gene silencing machineries. Accounts of Chemical Research. 45: 1122-31. PMID 22304792 DOI: 10.1021/Ar200253U |
0.501 |
|
| 2012 |
O'Brien SK, Knight KL, Rana TM. Phosphorylation of histone H1 by P-TEFb is a necessary step in skeletal muscle differentiation. Journal of Cellular Physiology. 227: 383-9. PMID 21503884 DOI: 10.1002/Jcp.22797 |
0.329 |
|
| 2012 |
Mccarroll JA, Baigude H, Erlich R, Dwarte T, Rana TM, Kavallaris M. Abstract 1969: Silencing αIII-tubulin by RNA interfering nanoparticles in non-small cell lung cancer Cancer Research. 72: 1969-1969. DOI: 10.1158/1538-7445.Am2012-1969 |
0.332 |
|
| 2011 |
Yang CS, Lopez CG, Rana TM. Discovery of nonsteroidal anti-inflammatory drug and anticancer drug enhancing reprogramming and induced pluripotent stem cell generation. Stem Cells (Dayton, Ohio). 29: 1528-36. PMID 21898684 DOI: 10.1002/Stem.717 |
0.334 |
|
| 2011 |
Li Z, Yang CS, Nakashima K, Rana TM. Small RNA-mediated regulation of iPS cell generation. The Embo Journal. 30: 823-34. PMID 21285944 DOI: 10.1038/Emboj.2011.2 |
0.304 |
|
| 2011 |
Su J, Baigude H, McCarroll J, Rana TM. Silencing microRNA by interfering nanoparticles in mice. Nucleic Acids Research. 39: e38. PMID 21212128 DOI: 10.1093/Nar/Gkq1307 |
0.309 |
|
| 2010 |
Ali A, Reddy GS, Nalam MN, Anjum SG, Cao H, Schiffer CA, Rana TM. Structure-based design, synthesis, and structure-activity relationship studies of HIV-1 protease inhibitors incorporating phenyloxazolidinones. Journal of Medicinal Chemistry. 53: 7699-708. PMID 20958050 DOI: 10.1021/Jm1008743 |
0.355 |
|
| 2010 |
Lu CC, Li Z, Chu CY, Feng J, Feng J, Sun R, Rana TM. MicroRNAs encoded by Kaposi's sarcoma-associated herpesvirus regulate viral life cycle. Embo Reports. 11: 784-90. PMID 20847741 DOI: 10.1038/Embor.2010.132 |
0.396 |
|
| 2010 |
Ghosh A, Mukherjee K, Jiang X, Zhou Y, McCarroll J, Qu J, Swain PM, Baigude H, Rana TM. Design and assembly of new nonviral RNAi delivery agents by microwave-assisted quaternization (MAQ) of tertiary amines. Bioconjugate Chemistry. 21: 1581-7. PMID 20722369 DOI: 10.1021/Bc900482R |
0.373 |
|
| 2010 |
James V, Zhang Y, Foxler DE, de Moor CH, Kong YW, Webb TM, Self TJ, Feng Y, Lagos D, Chu CY, Rana TM, Morley SJ, Longmore GD, Bushell M, Sharp TV. LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing. Proceedings of the National Academy of Sciences of the United States of America. 107: 12499-504. PMID 20616046 DOI: 10.1073/Pnas.0914987107 |
0.351 |
|
| 2010 |
O'Brien SK, Cao H, Nathans R, Ali A, Rana TM. P-TEFb kinase complex phosphorylates histone H1 to regulate expression of cellular and HIV-1 genes. The Journal of Biological Chemistry. 285: 29713-20. PMID 20551309 DOI: 10.1074/Jbc.M110.125997 |
0.398 |
|
| 2010 |
Nalam MN, Ali A, Altman MD, Reddy GS, Chellappan S, Kairys V, Ozen A, Cao H, Gilson MK, Tidor B, Rana TM, Schiffer CA. Evaluating the substrate-envelope hypothesis: structural analysis of novel HIV-1 protease inhibitors designed to be robust against drug resistance. Journal of Virology. 84: 5368-78. PMID 20237088 DOI: 10.1128/Jvi.02531-09 |
0.34 |
|
| 2010 |
McCarroll J, Baigude H, Yang CS, Rana TM. Nanotubes functionalized with lipids and natural amino acid dendrimers: a new strategy to create nanomaterials for delivering systemic RNAi. Bioconjugate Chemistry. 21: 56-63. PMID 19957956 DOI: 10.1021/Bc900296Z |
0.325 |
|
| 2009 |
Baigude H, Rana TM. Delivery of therapeutic RNAi by nanovehicles. Chembiochem : a European Journal of Chemical Biology. 10: 2449-54. PMID 19688785 DOI: 10.1002/Cbic.200900252 |
0.49 |
|
| 2009 |
Ali A, Ghosh A, Nathans RS, Sharova N, O'Brien S, Cao H, Stevenson M, Rana TM. Identification of flavopiridol analogues that selectively inhibit positive transcription elongation factor (P-TEFb) and block HIV-1 replication. Chembiochem : a European Journal of Chemical Biology. 10: 2072-80. PMID 19603446 DOI: 10.1002/Cbic.200900303 |
0.446 |
|
| 2009 |
Nathans R, Chu CY, Serquina AK, Lu CC, Cao H, Rana TM. Cellular microRNA and P bodies modulate host-HIV-1 interactions. Molecular Cell. 34: 696-709. PMID 19560422 DOI: 10.1016/J.Molcel.2009.06.003 |
0.423 |
|
| 2009 |
Bélanger F, Baigude H, Rana TM. U30 of 7SK RNA forms a specific photo-cross-link with Hexim1 in the context of both a minimal RNA-binding site and a fully reconstituted 7SK/Hexim1/P-TEFb ribonucleoprotein complex. Journal of Molecular Biology. 386: 1094-107. PMID 19244621 DOI: 10.1016/J.Jmb.2009.01.015 |
0.503 |
|
| 2009 |
Jorissen RN, Reddy GS, Ali A, Altman MD, Chellappan S, Anjum SG, Tidor B, Schiffer CA, Rana TM, Gilson MK. Additivity in the analysis and design of HIV protease inhibitors. Journal of Medicinal Chemistry. 52: 737-54. PMID 19193159 DOI: 10.1021/Jm8009525 |
0.348 |
|
| 2009 |
Ali A, Ghosh A, Nathans RS, Sharova N, O'Brien S, Cao H, Stevenson M, Rana TM. Cover Picture: Identification of Flavopiridol Analogues that Selectively Inhibit Positive Transcription Elongation Factor (P-TEFb) and Block HIV-1 Replication (ChemBioChem 12/2009) Chembiochem. 10: 1905-1905. DOI: 10.1002/Cbic.200990047 |
0.396 |
|
| 2008 |
Nathans R, Cao H, Sharova N, Ali A, Sharkey M, Stranska R, Stevenson M, Rana TM. Small-molecule inhibition of HIV-1 Vif. Nature Biotechnology. 26: 1187-92. PMID 18806783 DOI: 10.1038/Nbt.1496 |
0.381 |
|
| 2008 |
Cao H, Yang CS, Rana TM. Evolutionary emergence of microRNAs in human embryonic stem cells. Plos One. 3: e2820. PMID 18665260 DOI: 10.1371/Journal.Pone.0002820 |
0.324 |
|
| 2008 |
Chu CY, Rana TM. Potent RNAi by short RNA triggers. Rna (New York, N.Y.). 14: 1714-9. PMID 18658119 DOI: 10.1261/Rna.1161908 |
0.505 |
|
| 2008 |
Altman MD, Ali A, Reddy GS, Nalam MN, Anjum SG, Cao H, Chellappan S, Kairys V, Fernandes MX, Gilson MK, Schiffer CA, Rana TM, Tidor B. HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants. Journal of the American Chemical Society. 130: 6099-113. PMID 18412349 DOI: 10.1021/Ja076558P |
0.332 |
|
| 2008 |
Wang H, Ghosh A, Baigude H, Yang CS, Qiu L, Xia X, Zhou H, Rana TM, Xu Z. Therapeutic gene silencing delivered by a chemically modified small interfering RNA against mutant SOD1 slows amyotrophic lateral sclerosis progression. The Journal of Biological Chemistry. 283: 15845-52. PMID 18367449 DOI: 10.1074/Jbc.M800834200 |
0.357 |
|
| 2007 |
Reddy GS, Ali A, Nalam MN, Anjum SG, Cao H, Nathans RS, Schiffer CA, Rana TM. Design and synthesis of HIV-1 protease inhibitors incorporating oxazolidinones as P2/P2' ligands in pseudosymmetric dipeptide isosteres. Journal of Medicinal Chemistry. 50: 4316-28. PMID 17696512 DOI: 10.1021/Jm070284Z |
0.357 |
|
| 2007 |
Chu CY, Rana TM. Small RNAs: regulators and guardians of the genome. Journal of Cellular Physiology. 213: 412-9. PMID 17674365 DOI: 10.1002/Jcp.21230 |
0.44 |
|
| 2007 |
Chellappan S, Kiran Kumar Reddy GS, Ali A, Nalam MN, Anjum SG, Cao H, Kairys V, Fernandes MX, Altman MD, Tidor B, Rana TM, Schiffer CA, Gilson MK. Design of mutation-resistant HIV protease inhibitors with the substrate envelope hypothesis. Chemical Biology & Drug Design. 69: 298-313. PMID 17539822 DOI: 10.1111/J.1747-0285.2007.00514.X |
0.338 |
|
| 2007 |
Robb GB, Rana TM. RNA helicase A interacts with RISC in human cells and functions in RISC loading. Molecular Cell. 26: 523-37. PMID 17531811 DOI: 10.1016/J.Molcel.2007.04.016 |
0.504 |
|
| 2007 |
Chiu YL, Cao H, Rana TM. Quantitative analysis of RNA-mediated protein-protein interactions in living cells by FRET. Chemical Biology & Drug Design. 69: 233-9. PMID 17461970 DOI: 10.1111/J.1747-0285.2007.00501.X |
0.514 |
|
| 2007 |
Baigude H, McCarroll J, Yang CS, Swain PM, Rana TM. Design and creation of new nanomaterials for therapeutic RNAi. Acs Chemical Biology. 2: 237-41. PMID 17432823 DOI: 10.1021/Cb7000582 |
0.391 |
|
| 2007 |
Rana TM. Illuminating the silence: understanding the structure and function of small RNAs. Nature Reviews. Molecular Cell Biology. 8: 23-36. PMID 17183358 DOI: 10.1038/Nrm2085 |
0.485 |
|
| 2006 |
Ali A, Reddy GS, Cao H, Anjum SG, Nalam MN, Schiffer CA, Rana TM. Discovery of HIV-1 protease inhibitors with picomolar affinities incorporating N-aryl-oxazolidinone-5-carboxamides as novel P2 ligands. Journal of Medicinal Chemistry. 49: 7342-56. PMID 17149864 DOI: 10.1021/Jm060666P |
0.335 |
|
| 2006 |
Richter SN, Bélanger F, Zheng P, Rana TM. Dynamics of nascent mRNA folding and RNA-protein interactions: an alternative TAR RNA structure is involved in the control of HIV-1 mRNA transcription. Nucleic Acids Research. 34: 4278-92. PMID 16920743 DOI: 10.1093/Nar/Gkl499 |
0.535 |
|
| 2006 |
Chu CY, Rana TM. Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54. Plos Biology. 4: e210. PMID 16756390 DOI: 10.1371/Journal.Pbio.0040210 |
0.449 |
|
| 2006 |
Wichroski MJ, Robb GB, Rana TM. Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies. Plos Pathogens. 2: e41. PMID 16699599 DOI: 10.1371/Journal.Ppat.0020041 |
0.438 |
|
| 2006 |
Cao H, Tamilarasu N, Rana TM. Orientation and affinity of HIV-1 Tat fragments in Tat-TAR complex determined by fluorescence resonance energy transfer. Bioconjugate Chemistry. 17: 352-8. PMID 16536465 DOI: 10.1021/Bc050277U |
0.51 |
|
| 2005 |
Lee CW, Cao H, Ichiyama K, Rana TM. Design and synthesis of a novel peptidomimetic inhibitor of HIV-1 Tat-TAR interactions: squaryldiamide as a new potential bioisostere of unsubstituted guanidine. Bioorganic & Medicinal Chemistry Letters. 15: 4243-6. PMID 16054360 DOI: 10.1016/J.Bmcl.2005.06.077 |
0.514 |
|
| 2005 |
Chiu YL, Dinesh CU, Chu CY, Ali A, Brown KM, Cao H, Rana TM. Dissecting RNA-interference pathway with small molecules. Chemistry & Biology. 12: 643-8. PMID 15975509 DOI: 10.1016/J.Chembiol.2005.04.016 |
0.498 |
|
| 2005 |
Brown KM, Chu CY, Rana TM. Target accessibility dictates the potency of human RISC. Nature Structural & Molecular Biology. 12: 469-70. PMID 15852021 DOI: 10.1038/Nsmb931 |
0.397 |
|
| 2005 |
Ping YH, Rana TM. Mechanism of site-specific psoralen photoadducts formation in triplex DNA directed by psoralen-conjugated oligonucleotides. Biochemistry. 44: 2501-9. PMID 15709762 DOI: 10.1021/Bi0488707 |
0.578 |
|
| 2005 |
Robb GB, Brown KM, Khurana J, Rana TM. Specific and potent RNAi in the nucleus of human cells. Nature Structural & Molecular Biology. 12: 133-7. PMID 15643423 DOI: 10.1038/Nsmb886 |
0.497 |
|
| 2005 |
Wichroski MJ, Ichiyama K, Rana TM. Analysis of HIV-1 viral infectivity factor-mediated proteasome-dependent depletion of APOBEC3G: correlating function and subcellular localization. The Journal of Biological Chemistry. 280: 8387-96. PMID 15537645 DOI: 10.1074/Jbc.M408048200 |
0.324 |
|
| 2004 |
Ping YH, Chu CY, Cao H, Jacque JM, Stevenson M, Rana TM. Modulating HIV-1 replication by RNA interference directed against human transcription elongation factor SPT5. Retrovirology. 1: 46. PMID 15620346 DOI: 10.1186/1742-4690-1-46 |
0.657 |
|
| 2004 |
Chiu YL, Ali A, Chu CY, Cao H, Rana TM. Visualizing a correlation between siRNA localization, cellular uptake, and RNAi in living cells. Chemistry & Biology. 11: 1165-75. PMID 15324818 DOI: 10.1016/J.Chembiol.2004.06.006 |
0.435 |
|
| 2004 |
Chiu YL, Cao H, Jacque JM, Stevenson M, Rana TM. Inhibition of human immunodeficiency virus type 1 replication by RNA interference directed against human transcription elongation factor P-TEFb (CDK9/CyclinT1). Journal of Virology. 78: 2517-29. PMID 14963154 DOI: 10.1128/Jvi.78.5.2517-2529.2004 |
0.468 |
|
| 2003 |
Gelman MA, Richter S, Cao H, Umezawa N, Gellman SH, Rana TM. Selective binding of TAR RNA by a Tat-derived beta-peptide. Organic Letters. 5: 3563-5. PMID 14507173 DOI: 10.1021/Ol034977V |
0.427 |
|
| 2003 |
Chiu YL, Rana TM. siRNA function in RNAi: a chemical modification analysis. Rna (New York, N.Y.). 9: 1034-48. PMID 12923253 DOI: 10.1261/Rna.5103703 |
0.491 |
|
| 2003 |
Hwang S, Tamilarasu N, Kibler K, Cao H, Ali A, Ping YH, Jeang KT, Rana TM. Discovery of a small molecule Tat-trans-activation-responsive RNA antagonist that potently inhibits human immunodeficiency virus-1 replication. The Journal of Biological Chemistry. 278: 39092-103. PMID 12857725 DOI: 10.1074/Jbc.M301749200 |
0.672 |
|
| 2003 |
Hamma T, Saleh A, Huq I, Rana TM, Miller PS. Inhibition of HIV tat-TAR interactions by an antisense oligo-2'-O-methylribonucleoside methylphosphonate. Bioorganic & Medicinal Chemistry Letters. 13: 1845-8. PMID 12749881 DOI: 10.1016/S0960-894X(03)00323-8 |
0.444 |
|
| 2002 |
Kesavan V, Tamilarasu N, Cao H, Rana TM. A new class of RNA-binding oligomers: peptoid amide and ester analogues. Bioconjugate Chemistry. 13: 1171-5. PMID 12440849 DOI: 10.1021/Bc0255642 |
0.547 |
|
| 2002 |
Chiu YL, Ho CK, Saha N, Schwer B, Shuman S, Rana TM. Tat stimulates cotranscriptional capping of HIV mRNA. Molecular Cell. 10: 585-97. PMID 12408826 DOI: 10.1016/S1097-2765(02)00630-5 |
0.428 |
|
| 2002 |
Chiu YL, Rana TM. RNAi in human cells: basic structural and functional features of small interfering RNA. Molecular Cell. 10: 549-61. PMID 12408823 DOI: 10.1016/S1097-2765(02)00652-4 |
0.494 |
|
| 2002 |
Zhou C, Rana TM. A bimolecular mechanism of HIV-1 Tat protein interaction with RNA polymerase II transcription elongation complexes. Journal of Molecular Biology. 320: 925-42. PMID 12126615 DOI: 10.1016/S0022-2836(02)00556-9 |
0.539 |
|
| 2002 |
Richter S, Ping YH, Rana TM. TAR RNA loop: a scaffold for the assembly of a regulatory switch in HIV replication. Proceedings of the National Academy of Sciences of the United States of America. 99: 7928-33. PMID 12048247 DOI: 10.1073/Pnas.122119999 |
0.699 |
|
| 2002 |
Richter S, Cao H, Rana TM. Specific HIV-1 TAR RNA loop sequence and functional groups are required for human cyclin T1-Tat-TAR ternary complex formation. Biochemistry. 41: 6391-7. PMID 12009901 DOI: 10.1021/Bi0159579 |
0.527 |
|
| 2002 |
Dinman JD, Richter S, Plant EP, Taylor RC, Hammell AB, Rana TM. The frameshift signal of HIV-1 involves a potential intramolecular triplex RNA structure. Proceedings of the National Academy of Sciences of the United States of America. 99: 5331-6. PMID 11959986 DOI: 10.1073/Pnas.082102199 |
0.682 |
|
| 2001 |
Wang Z, Shah K, Rana TM. Probing Tat peptide-TAR RNA interactions by psoralen photo-cross-linking Biochemistry. 40: 6458-6464. PMID 11371209 DOI: 10.1021/Bi0028744 |
0.519 |
|
| 2001 |
Tamilarasu N, Zhang J, Hwang S, Rana TM. A new strategy for site-specific protein modification: Analysis of a TAT peptide-tar RNA interaction Bioconjugate Chemistry. 12: 135-138. PMID 11312672 DOI: 10.1021/Bc000104Z |
0.414 |
|
| 2001 |
Chiu YL, Coronel E, Ho CK, Shuman S, Rana TM. HIV-1 Tat Protein Interacts with Mammalian Capping Enzyme and Stimulates Capping of TAR RNA Journal of Biological Chemistry. 276: 12959-12966. PMID 11278368 DOI: 10.1074/Jbc.M007901200 |
0.479 |
|
| 2001 |
Tamilarasu N, Huq I, Rana TM. Targeting RNA with peptidomimetic oligomers in human cells Bioorganic and Medicinal Chemistry Letters. 11: 505-507. PMID 11229758 DOI: 10.1016/S0960-894X(00)00709-5 |
0.556 |
|
| 2001 |
Ping YH, Rana TM. DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation. The Journal of Biological Chemistry. 276: 12951-8. PMID 11112772 DOI: 10.1074/Jbc.M006130200 |
0.682 |
|
| 2000 |
Hwang S, Tamilarasu N, Rana TM. Selection of HIV replication inhibitors: Chemistry and biology Advances in Pharmacology. 49: 167-197. PMID 11013764 DOI: 10.1016/S1054-3589(00)49027-7 |
0.518 |
|
| 2000 |
Zhang J, Tamilarasu N, Hwang S, Garber ME, Huq I, Jones KA, Rana TM. HIV-1 TAR RNA enhances the interaction between Tat and cyclin T1. The Journal of Biological Chemistry. 275: 34314-9. PMID 10944537 DOI: 10.1074/Jbc.M006804200 |
0.539 |
|
| 2000 |
Tamilarasu N, Huq I, Rana TM. Design, synthesis, and biological activity of a cyclic peptide: An inhibitor of HIV-1 Tat-TAR interactions in human cells Bioorganic and Medicinal Chemistry Letters. 10: 971-974. PMID 10853671 DOI: 10.1016/S0960-894X(00)00140-2 |
0.495 |
|
| 1999 |
Hwang S, Tamilarasu N, Ryan K, Huq I, Richter S, Still WC, Rana TM. Inhibition of gene expression in human cells through small molecule-RNA interactions. Proceedings of the National Academy of Sciences of the United States of America. 96: 12997-3002. PMID 10557261 DOI: 10.1073/Pnas.96.23.12997 |
0.536 |
|
| 1999 |
Wang Z, Rana TM. Probing RNA-protein interactions by psoralen photocrosslinking Methods in Molecular Biology (Clifton, N.J.). 118: 49-62. PMID 10549514 DOI: 10.1385/1-59259-676-2:49 |
0.436 |
|
| 1999 |
Wang Z, Huq I, Rana TM. Proximity of a Tat peptide to the HIV-1 TAR RNA loop region determined by site-specific photo-cross-linking Bioconjugate Chemistry. 10: 512-519. PMID 10346885 DOI: 10.1021/Bc980145J |
0.528 |
|
| 1999 |
Rana TM, Jeang KT. Biochemical and functional interactions between HIV-1 Tat protein and TAR RNA Archives of Biochemistry and Biophysics. 365: 175-185. PMID 10328810 DOI: 10.1006/Abbi.1999.1206 |
0.488 |
|
| 1999 |
Huq I, Ping YH, Tamilarasu N, Rana TM. Controlling human immunodeficiency virus type 1 gene expression by unnatural peptides. Biochemistry. 38: 5172-7. PMID 10213623 DOI: 10.1021/Bi982638H |
0.694 |
|
| 1999 |
Ping YH, Rana TM. Tat-associated kinase (P-TEFb): a component of transcription preinitiation and elongation complexes. The Journal of Biological Chemistry. 274: 7399-404. PMID 10066804 DOI: 10.1074/Jbc.274.11.7399 |
0.676 |
|
| 1999 |
Huq I, Tamilarasu N, Rana TM. Visualizing tertiary folding of RNA and RNA-protein interactions by a tethered iron chelate: Analysis of HIV-1 Tat-TAR complex Nucleic Acids Research. 27: 1084-1093. PMID 9927743 DOI: 10.1093/Nar/27.4.1084 |
0.523 |
|
| 1999 |
Tamilarasu N, Huq I, Rana TM. High affinity and specific binding of HIV-1 TAR RNA by a tat-derived oligourea [1] Journal of the American Chemical Society. 121: 1597-1598. DOI: 10.1021/Ja983822T |
0.477 |
|
| 1998 |
Wang Z, Rana TM. RNA-protein interactions in the Tat-trans-activation response element complex determined by site-specific photo-cross-linking. Biochemistry. 37: 4235-43. PMID 9521746 DOI: 10.1021/Bi972889A |
0.509 |
|
| 1997 |
Huq I, Rana TM. Probing the proximity of the core domain of an HIV-1 Tat fragment in a Tat-TAR complex by affinity cleaving Biochemistry. 36: 12592-12599. PMID 9376365 DOI: 10.1021/Bi971011G |
0.498 |
|
| 1997 |
Huq I, Wang X, Rana TM. Specific recognition of HIV-1 TAR RNA by a D-Tat peptide Nature Structural Biology. 4: 881-882. PMID 9360598 DOI: 10.1038/Nsb1197-881 |
0.447 |
|
| 1997 |
Ping YH, Liu Y, Wang X, Neenhold HR, Rana TM. Dynamics of RNA-protein interactions in the HIV-1 Rev-RRE complex visualized by 6-thioguanosine-mediated photocrosslinking. Rna (New York, N.Y.). 3: 850-60. PMID 9257644 |
0.647 |
|
| 1997 |
Wang Z, Rana TM. DNA damage-dependent transcriptional arrest and termination of RNA polymerase II elongation complexes in DNA template containing HIV-1 promoter Proceedings of the National Academy of Sciences of the United States of America. 94: 6688-6693. PMID 9192626 DOI: 10.1073/Pnas.94.13.6688 |
0.408 |
|
| 1997 |
Wang X, Huq I, Rana TM. HIV-1 TAR RNA Recognition by an Unnatural Biopolymer Journal of the American Chemical Society. 119: 6444-6445. DOI: 10.1021/Ja963895H |
0.486 |
|
| 1996 |
Shah K, Neenhold H, Wang Z, Rana TM. Incorporation of an artificial protease and nuclease at the HIV-1 tat binding site of trans-activation responsive RNA Bioconjugate Chemistry. 7: X1-289. PMID 8816949 DOI: 10.1021/Bc960023W |
0.504 |
|
| 1996 |
Wang Z, Wang X, Rana TM. Protein orientation in the Tat-TAR complex determined by psoralen photocross-linking Journal of Biological Chemistry. 271: 16995-16998. PMID 8663586 DOI: 10.1074/Jbc.271.29.16995 |
0.536 |
|
| 1996 |
Wang Z, Rana TM. RNA conformation in the Tat-TAR complex determined by site-specific photo-cross-linking Biochemistry. 35: 6491-6499. PMID 8639596 DOI: 10.1021/Bi960037P |
0.499 |
|
| 1996 |
Liu Y, Wang Z, Rana TM. Visualizing a specific contact in the HIV-1 Tat protein fragment and trans-activation responsive region RNA complex by photocross-linking Journal of Biological Chemistry. 271: 10391-10396. PMID 8626612 DOI: 10.1074/Jbc.271.17.10391 |
0.534 |
|
| 1995 |
Rana TM. Major groove opening at the HIV-1 tat binding site of TAR RNA evidenced by a rhodium probe Biochemistry®. 34: 6303-6309. PMID 7756257 DOI: 10.1021/Bi00019A007 |
0.522 |
|
| 1995 |
Wang Z, Rana TM. Chemical conversion of a trans-activation responsive RNA-binding fragment of HIV-1 Tat protein into a site-specific cross-linking agent Journal of the American Chemical Society. 117: 5438-5444. DOI: 10.1021/Ja00125A002 |
0.531 |
|
| 1994 |
Shah K, Wu H, Rana TM. Synthesis of uridine phosphoramidite analogs: Reagents for site-specific incorporation of photoreactive sites into RNA sequences Bioconjugate Chemistry. 5: 508-512. PMID 7533002 DOI: 10.1021/Bc00030A005 |
0.419 |
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