| Year |
Citation |
Score |
| 2011 |
Troll W, Shapiro R. Action of Environmental Agents on Nucleic Acids and Their Metabolism Comprehensive Physiology. DOI: 10.1002/Cphy.Cp090140 |
0.333 |
|
| 2009 |
Donny-Clark K, Shapiro R, Broyde S. Accommodation of an N-(deoxyguanosin-8-yl)-2-acetylaminofluorene adduct in the active site of human DNA polymerase iota: Hoogsteen or Watson-Crick base pairing? Biochemistry. 48: 7-18. PMID 19072536 DOI: 10.1021/Bi801283D |
0.607 |
|
| 2008 |
Ding S, Shapiro R, Cai Y, Geacintov NE, Broyde S. Conformational properties of equilenin-DNA adducts: stereoisomer and base effects. Chemical Research in Toxicology. 21: 1064-73. PMID 18416538 DOI: 10.1021/Tx800010U |
0.681 |
|
| 2007 |
Ding S, Shapiro R, Geacintov NE, Broyde S. 4-hydroxyequilenin-adenine lesions in DNA duplexes: stereochemistry, damage site, and structure. Biochemistry. 46: 182-91. PMID 17198388 DOI: 10.1021/Bi061652O |
0.694 |
|
| 2006 |
Zhang L, Rechkoblit O, Wang L, Patel DJ, Shapiro R, Broyde S. Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): modeling and dynamics studies. Nucleic Acids Research. 34: 3326-37. PMID 16820532 DOI: 10.1093/Nar/Gkl425 |
0.606 |
|
| 2006 |
Jia L, Shafirovich V, Shapiro R, Geacintov NE, Broyde S. Flexible 5-guanidino-4-nitroimidazole DNA lesions: structures and thermodynamics. Biochemistry. 45: 6644-55. PMID 16716075 DOI: 10.1021/Bi0601757 |
0.701 |
|
| 2005 |
Ding S, Shapiro R, Geacintov NE, Broyde S. Equilenin-derived DNA adducts to cytosine in DNA duplexes: structures and thermodynamics. Biochemistry. 44: 14565-76. PMID 16262256 DOI: 10.1021/Bi051090T |
0.682 |
|
| 2005 |
Jia L, Shafirovich V, Shapiro R, Geacintov NE, Broyde S. Structural and thermodynamic features of spiroiminodihydantoin damaged DNA duplexes. Biochemistry. 44: 13342-53. PMID 16201759 DOI: 10.1021/Bi050790V |
0.715 |
|
| 2005 |
Zhang L, Shapiro R, Broyde S. Molecular dynamics of a food carcinogen-DNA adduct in a replicative DNA polymerase suggest hindered nucleotide incorporation and extension. Chemical Research in Toxicology. 18: 1347-63. PMID 16167826 DOI: 10.1021/Tx050132B |
0.616 |
|
| 2005 |
Jia L, Shafirovich V, Shapiro R, Geacintov NE, Broyde S. Spiroiminodihydantoin lesions derived from guanine oxidation: structures, energetics, and functional implications. Biochemistry. 44: 6043-51. PMID 15835893 DOI: 10.1021/Bi0473657 |
0.705 |
|
| 2004 |
Wang L, Hingerty BE, Shapiro R, Broyde S. Structural and stereoisomer effects of model estrogen quinone-derived DNA adducts: N6-(2-hydroxyestron-6(alpha,beta)-yl)-2'-deoxyadenosine and N2-(2-hydroxyestron-6(alpha,beta)-yl)-2'-deoxyguanosine. Chemical Research in Toxicology. 17: 311-24. PMID 15025501 DOI: 10.1021/Tx034218L |
0.567 |
|
| 2003 |
Tonan K, Xu P, Jenkins JL, Russo A, Shapiro R, Ni F. Unexpected binding mode for 2'-phosphoadenosine-based nucleotide inhibitors in complex with human angiogenin revealed by heteronuclear NMR spectroscopy. Biochemistry. 42: 11137-49. PMID 14503864 DOI: 10.1021/Bi030066H |
0.348 |
|
| 2003 |
Ding S, Shapiro R, Geacintov NE, Broyde S. Conformations of stereoisomeric base adducts to 4-hydroxyequilenin. Chemical Research in Toxicology. 16: 695-707. PMID 12807352 DOI: 10.1021/Tx0340246 |
0.672 |
|
| 2003 |
Jenkins JL, Shapiro R. Identification of small-molecule inhibitors of human angiogenin and characterization of their binding interactions guided by computational docking. Biochemistry. 42: 6674-87. PMID 12779322 DOI: 10.1021/Bi034164E |
0.301 |
|
| 2003 |
Teufel DP, Kao RY, Acharya KR, Shapiro R. Mutational analysis of the complex of human RNase inhibitor and human eosinophil-derived neurotoxin (RNase 2). Biochemistry. 42: 1451-9. PMID 12578357 DOI: 10.1021/Bi026852O |
0.336 |
|
| 2002 |
Holloway DE, Shapiro R, Hares MC, Leonidas DD, Acharya KR. Guest-host crosstalk in an angiogenin - RNase a chimeric protein Biochemistry. 41: 10482-10489. PMID 12173935 DOI: 10.1021/Bi026151R |
0.333 |
|
| 2001 |
Yan S, Shapiro R, Geacintov NE, Broyde S. Stereochemical, structural, and thermodynamic origins of stability differences between stereoisomeric benzo[a]pyrene diol epoxide deoxyadenosine adducts in a DNA mutational hot spot sequence. Journal of the American Chemical Society. 123: 7054-66. PMID 11459484 DOI: 10.1021/Ja0043035 |
0.671 |
|
| 2001 |
Gauvin J, Broyde S, Shapiro R. The food mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline: a conformational analysis of its major DNA adduct and comparison with the 2-amino-3-methylimidazo[4,5-f]quinoline adduct. Chemical Research in Toxicology. 14: 476-82. PMID 11368544 DOI: 10.1021/Tx000144R |
0.601 |
|
| 2000 |
Shapiro R. A replicator was not involved in the origin of life. Iubmb Life. 49: 173-176. PMID 10868906 DOI: 10.1080/713803621 |
0.31 |
|
| 1999 |
Wu X, Shapiro R, Broyde S. Conformational analysis of the major DNA adduct derived from the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline. Chemical Research in Toxicology. 12: 895-905. PMID 10525264 DOI: 10.1021/Tx990108W |
0.609 |
|
| 1999 |
Russo N, Shapiro R. Potent inhibition of mammalian ribonucleases by 3', 5'-pyrophosphate-linked nucleotides. The Journal of Biological Chemistry. 274: 14902-8. PMID 10329690 DOI: 10.1074/Jbc.274.21.14902 |
0.317 |
|
| 1999 |
Shapiro R. Prebiotic cytosine synthesis: a critical analysis and implications for the origin of life. Proceedings of the National Academy of Sciences of the United States of America. 96: 4396-4401. PMID 10200273 DOI: 10.1073/Pnas.96.8.4396 |
0.309 |
|
| 1998 |
Roy D, Hingerty BE, Shapiro R, Broyde S. A slipped replication intermediate model is stabilized by the syn orientation of N-2-aminofluorene- and N-2-(acetyl)aminofluorene-modified guanine at a mutational hotspot. Chemical Research in Toxicology. 11: 1301-11. PMID 9815190 DOI: 10.1021/Tx980106W |
0.58 |
|
| 1998 |
Shapiro R. Structural features that determine the enzymatic potency and specificity of human angiogenin: threonine-80 and residues 58-70 and 116-123. Biochemistry. 37: 6847-6856. PMID 9578571 DOI: 10.1021/Bi9800146 |
0.36 |
|
| 1998 |
Shapiro R, Ellis S, Hingerty BE, Broyde S. Effect of ring size on conformations of aromatic amine-DNA adducts: the aniline-C8 guanine adduct resides in the B-DNA major groove. Chemical Research in Toxicology. 11: 335-41. PMID 9548804 DOI: 10.1021/Tx970211Q |
0.621 |
|
| 1997 |
Grad R, Shapiro R, Hingerty BE, Broyde S. A molecular mechanics and dynamics study of the minor adduct between DNA and the carcinogen 2-(acetylamino)fluorene (dG-N2-AAF). Chemical Research in Toxicology. 10: 1123-32. PMID 9348435 DOI: 10.1021/Tx970092E |
0.588 |
|
| 1997 |
Chen C, Shapiro R. Site-specific mutagenesis reveals differences in the structural bases for tight binding of RNase inhibitor to angiogenin and RNase A Proceedings of the National Academy of Sciences of the United States of America. 94: 1761-1766. PMID 9050852 DOI: 10.1073/Pnas.94.5.1761 |
0.337 |
|
| 1996 |
Nolan SJ, Vyas RR, Hingerty BE, Ellis S, Broyde S, Shapiro R, Basu AK. Solution properties and computational analysis of an oligodeoxynucleotide containing N-(deoxyguanosin-8-yl)-1-aminopyrene. Carcinogenesis. 17: 133-44. PMID 8565123 DOI: 10.1093/Carcin/17.1.133 |
0.627 |
|
| 1995 |
Shapiro R. The prebiotic role of adenine: A critical analysis Origins of Life and Evolution of the Biosphere. 25: 83-98. PMID 11536683 DOI: 10.1007/Bf01581575 |
0.325 |
|
| 1995 |
Shapiro R, Ellis S, Hingerty BE, Broyde S. Major and minor groove conformations of DNA trimers modified on guanine or adenine by 4-aminobiphenyl: adenine adducts favor the minor groove. Chemical Research in Toxicology. 8: 117-27. PMID 7703355 DOI: 10.1021/Tx00043A016 |
0.608 |
|
| 1994 |
Shapiro R, Sidawi D, Miao YS, Hingerty BE, Schmidt KE, Moskowitz J, Broyde S. Conformation of amine-modified DNA: 2-aminofluorene- and 2-(acetylamino)fluorene-modified deoxydinucleoside monophosphates with all possible nearest neighbors. A comparison of search and optimization methods. Chemical Research in Toxicology. 7: 239-53. PMID 8199314 DOI: 10.1021/Tx00038A018 |
0.595 |
|
| 1994 |
Singh SB, Li B, Hingerty BE, Shapiro R, Broyde S. Molecular dynamics simulation of a tumorigenic benzo[a]pyrene metabolite bound to DNA at a single strand-double strand junction. Annals of the New York Academy of Sciences. 726: 57-70. PMID 8092708 DOI: 10.1111/J.1749-6632.1994.Tb52798.X |
0.591 |
|
| 1994 |
Allen SC, Acharya KR, Palmer KA, Shapiro R, Vallee BL, Scheraga HA. A comparison of the predicted and X-ray structures of angiogenin. Implications for further studies of model building of homologous proteins. Journal of Protein Chemistry. 13: 649-58. PMID 7702747 DOI: 10.1007/Bf01890464 |
0.307 |
|
| 1993 |
Curran TP, Shapiro R, James F. R, Vallee BL. Modulation of the activity of angiogenin by mutagenesis at Asp-116 Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 1202: 281-286. PMID 7691185 DOI: 10.1016/0167-4838(93)90017-L |
0.33 |
|
| 1992 |
Hallahan TW, Shapiro R, Strydom DJ, Vallee BL. Importance of asparagine-61 and asparagine-109 to the angiogenic activity to human angiotensin Biochemistry. 31: 8022-8029. PMID 1380830 DOI: 10.1021/Bi00149A036 |
0.311 |
|
| 1991 |
Hallahan TW, Shapiro R, Vallee BL. Dual site model for the organogenic activity of angiogenin Proceedings of the National Academy of Sciences of the United States of America. 88: 2222-2226. PMID 2006161 DOI: 10.1073/Pnas.88.6.2222 |
0.317 |
|
| 1989 |
Shapiro R, Hingerty BE, Broyde S. Minor-groove binding models for acetylaminofluorene modified DNA. Journal of Biomolecular Structure & Dynamics. 7: 493-513. PMID 2627297 DOI: 10.1080/07391102.1989.10508506 |
0.604 |
|
| 1989 |
Shapiro R, Fox EA, Riordan JF. Role of lysines in human angiogenin: chemical modification and site-directed mutagenesis. Biochemistry. 28: 1726-32. PMID 2497770 DOI: 10.1021/Bi00430A045 |
0.316 |
|
| 1988 |
Shapiro R, Strydom DJ, Weremowicz S, Vallee BL. Sites of modification of human angiogenin by bromoacetate at pH 5.5 Biochemical and Biophysical Research Communications. 156: 530-536. PMID 3178849 DOI: 10.1016/S0006-291X(88)80874-X |
0.305 |
|
| 1988 |
Underwood GR, Price MF, Shapiro R. A new synthetic route to nucleotide adducts derived from N-acetylated and unacetylated 4-aminobiphenyl. Carcinogenesis. 9: 1817-21. PMID 3168160 DOI: 10.1093/Carcin/9.10.1817 |
0.311 |
|
| 1988 |
Jacobson MD, Shapiro R, Underwood GR, Broyde S, Verna L, Hingerty BE. Synthesis and conformation of a dinucleoside monophosphate modified by aniline. Chemical Research in Toxicology. 1: 152-9. PMID 2979725 DOI: 10.1021/Tx00003A005 |
0.566 |
|
| 1988 |
Sodum RS, Shapiro R. Reaction of acrolein with cytosine and adenine derivatives Bioorganic Chemistry. 16: 272-282. DOI: 10.1016/0045-2068(88)90015-6 |
0.365 |
|
| 1987 |
Shapiro R, Weremowicz S, Riordan JF, Vallee BL. Ribonucleolytic activity of angiogenin: essential histidine, lysine, and arginine residues Proceedings of the National Academy of Sciences of the United States of America. 84: 8783-8787. PMID 3122207 DOI: 10.1073/Pnas.84.24.8783 |
0.338 |
|
| 1986 |
Shapiro R, Underwood GR, Zawadzka H, Broyde S, Hingerty BE. Conformation of d(CpG) modified by the carcinogen 4-aminobiphenyl: a combined experimental and theoretical analysis. Biochemistry. 25: 2198-205. PMID 3707942 DOI: 10.1021/Bi00356A052 |
0.591 |
|
| 1986 |
Shapiro R, Fett JW, Strydom DJ, Vallee BL. Isolation and characterization of a human colon carcinoma-secreted enzyme with pancreatic ribonuclease-like activity Biochemistry. 25: 7255-7264. PMID 3467790 DOI: 10.1021/Bi00371A002 |
0.307 |
|
| 1986 |
Shapiro R, Riordan JF, Vallee BL. Characteristic ribonucleolytic activity of human angiogenin Biochemistry. 25: 3527-3532. PMID 2424496 DOI: 10.1021/Bi00360A008 |
0.318 |
|
| 1983 |
Shapiro R, Riordan JF. Critical lysine residue at the chloride binding site of angiotensin converting enzyme. Biochemistry. 22: 5315-5321. PMID 6317019 DOI: 10.1021/Bi00292A010 |
0.304 |
|
| 1983 |
Sethi SK, Gelijkens CF, McCloskey JA, Shapiro R, Brandes BA. Mass sectrometric study of methylene cross‐linked derivatives of adenine and adenosine Journal of Mass Spectrometry. 10: 665-670. DOI: 10.1002/Bms.1200101209 |
0.309 |
|
| 1980 |
Chaw YFM, Crane LE, Lange P, Shapiro R. Isolation and identification of cross-links from formaldehyde-treated nucleic acids. Biochemistry. 19: 5525-5531. PMID 7459328 DOI: 10.1021/Bi00565A010 |
0.335 |
|
| 1977 |
Shapiro R, Gazit A. Crosslinking of nucleic acids and proteins by bisulfite. Advances in Experimental Medicine and Biology. 633-640. PMID 920510 DOI: 10.1007/978-1-4684-3282-4_37 |
0.336 |
|
| 1977 |
Brown HS, Shapiro R. Conformation of aromatic-substituted dinucleoside monophosphates: an extension of the base-displacement theory of carcinogenesis. Biochemistry. 16: 1229-35. PMID 849414 DOI: 10.1021/Bi00625A031 |
0.363 |
|
| 1977 |
Brown HS, Shapiro R. Preparation and enzymatic hydrolysis of dinucleoside monophosphates and DNA modified with aromatic residues. Biochimica Et Biophysica Acta. 475: 241-53. PMID 557343 DOI: 10.1016/0005-2787(77)90015-6 |
0.387 |
|
| 1977 |
Dubelman S, Shapiro R. A method for the isolation of cross-linked nucleosides from DNA: application to cross-links induced by nitrous acid Nucleic Acids Research. 4: 1815-1828. PMID 197494 DOI: 10.1093/Nar/4.6.1815 |
0.329 |
|
| 1976 |
Shapiro R, Welcher M, Nelson V, Fate VD. Reaction of uracil and thymine derivatives with sodium bisulfite. Studies on the mechanism and reduction of the adduct. Biochimica Et Biophysica Acta. 425: 115-124. PMID 2323 DOI: 10.1016/0005-2787(76)90221-5 |
0.3 |
|
| 1974 |
Schulman LH, Shapiro R, Law DC, Louis JB. A simplified method for study of RNA conformation--reaction of formylmethionine transfer RNA with [14C]methylamine-bisulfite. Nucleic Acids Research. 1: 1305-16. PMID 10793691 DOI: 10.1093/Nar/1.10.1305 |
0.309 |
|
| 1973 |
Shapiro R, Danzig M. Acidic hydrolysis of pyrimidine deoxyribonucleotides. Biochimica Et Biophysica Acta. 319: 5-10. PMID 4739047 DOI: 10.1016/0005-2787(73)90035-X |
0.328 |
|
| 1972 |
Shapiro R, Yamaguchi H. Nucleic acid reactivity and conformation I. Deamination of cytosine by nitrous acid Biochimica Et Biophysica Acta. 281: 501-506. PMID 4653128 DOI: 10.1016/0005-2787(72)90150-5 |
0.331 |
|
| 1972 |
Shapiro R, Law DC, Weisgras JM. A new chemical probe for single-stranded RNA. Biochemical and Biophysical Research Communications. 49: 358-63. PMID 4344885 DOI: 10.1016/0006-291X(72)90418-4 |
0.325 |
|
| 1970 |
Shapiro R, Weisgras JM. Bisulfite-catalyzed transamination of cytosine and cytidine. Biochemical and Biophysical Research Communications. 40: 839-843. PMID 5495733 DOI: 10.1016/0006-291X(70)90979-4 |
0.318 |
|
| 1970 |
Shapiro R, Cohen BI, Servis RE. Specific Deamination of RNA by Sodium Bisulphite Nature. 227: 1047-1048. PMID 5449768 DOI: 10.1038/2271047A0 |
0.332 |
|
| 1968 |
Shapiro R. Chemistry of Guanine and Its Biologically Significant Derivatives Progress in Nucleic Acid Research and Molecular Biology. 8: 73-112. DOI: 10.1016/S0079-6603(08)60544-9 |
0.324 |
|
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