| Year |
Citation |
Score |
| 2022 |
Wender PA, Luu-Nguyen QH, Sloane JL, Ranjan A. Trimethylene Methane Dianion Equivalent for the Asymmetric Consecutive Allylation of Aldehydes: Applications to Prins-Driven Macrocyclizations for the Synthesis of Bryostatin 1 and Analogues. The Journal of Organic Chemistry. PMID 36378802 DOI: 10.1021/acs.joc.2c02047 |
0.343 |
|
| 2020 |
Wender PA, Sloane JL, Luu-Nguyen QH, Ogawa Y, Shimizu AJ, Ryckbosch SM, Tyler JH, Hardman C. Function-Oriented Synthesis: Design, Synthesis, and Evaluation of Highly Simplified Bryostatin Analogues. The Journal of Organic Chemistry. PMID 33200928 DOI: 10.1021/acs.joc.0c01988 |
0.3 |
|
| 2020 |
Sloane JL, Benner NL, Keenan KN, Zang X, Soliman MSA, Wu X, Dimapasoc M, Chun TW, Marsden MD, Zack JA, Wender PA. Prodrugs of PKC modulators show enhanced HIV latency reversal and an expanded therapeutic window. Proceedings of the National Academy of Sciences of the United States of America. PMID 32371485 DOI: 10.1073/Pnas.1919408117 |
0.306 |
|
| 2020 |
Hardman C, Ho S, Shimizu A, Luu-Nguyen Q, Sloane JL, Soliman MSA, Marsden MD, Zack JA, Wender PA. Synthesis and evaluation of designed PKC modulators for enhanced cancer immunotherapy. Nature Communications. 11: 1879. PMID 32312992 DOI: 10.1038/S41467-020-15742-7 |
0.367 |
|
| 2019 |
Singh J, Ripp A, Haas TM, Qiu D, Keller M, Wender PA, Siegel JS, Baldridge KK, Jessen HJ. Correction to "Synthesis of Modified Nucleoside Oligophosphates Simplified: Fast, Pure, and Protecting Group Free". Journal of the American Chemical Society. PMID 31580654 DOI: 10.1021/Jacs.9B10441 |
0.313 |
|
| 2019 |
Singh J, Ripp A, Haas TM, Qiu D, Keller M, Wender PA, Siegel JS, Baldridge KK, Jessen HJ. Synthesis of modified nucleoside oligophosphates simplified: Fast, pure, and protecting group free. Journal of the American Chemical Society. PMID 31512870 DOI: 10.1021/Jacs.9B08273 |
0.351 |
|
| 2019 |
Antonoplis A, Zang X, Wegner T, Wender PA, Cegelski L. Vancomycin-Arginine Conjugate Inhibits Growth of Carbapenem-Resistant and Targets Cell-Wall Synthesis. Acs Chemical Biology. PMID 31479234 DOI: 10.1021/Acschembio.9B00565 |
0.303 |
|
| 2019 |
Benner NL, McClellan RL, Turlington CR, Haabeth OAW, Waymouth RM, Wender PA. Oligo(serine ester) Charge-Altering Releasable Transporters: Organocatalytic Ring-Opening Polymerization and their Use for in Vitro and in Vivo mRNA Delivery. Journal of the American Chemical Society. PMID 31083999 DOI: 10.1021/Jacs.9B03154 |
0.306 |
|
| 2019 |
Singh J, Steck N, De D, Hofer A, Ripp A, Captain I, Keller M, Wender P, Bhandari R, Jessen HJ. The cyclic phosphoramidite reagent c-PyPA enables iterative polyphosphorylations. Angewandte Chemie (International Ed. in English). PMID 30681761 DOI: 10.1002/Anie.201814366 |
0.321 |
|
| 2018 |
Benner NL, Near KE, Bachmann MH, Contag CH, Waymouth RM, Wender PA. Functional DNA Delivery Enabled by Lipid-Modified Charge-Altering Releasable Transporters (CARTs). Biomacromolecules. PMID 29727572 DOI: 10.1021/Acs.Biomac.8B00401 |
0.748 |
|
| 2017 |
Wender PA. Gilbert Stork (1921-2017). Nature. 551: 566. PMID 32080670 DOI: 10.1038/D41586-017-07527-8 |
0.344 |
|
| 2017 |
Wender PA, Ebner C, Fennell BD, Inagaki F, Schröder B. Ynol Ethers as Ketene Equivalents in Rhodium-Catalyzed Intermolecular [5 + 2] Cycloaddition Reactions. Organic Letters. PMID 29034684 DOI: 10.1021/Acs.Orglett.7B02765 |
0.44 |
|
| 2017 |
Wender PA, Hardman CT, Ho S, Jeffreys MS, Maclaren JK, Quiroz RV, Ryckbosch SM, Shimizu AJ, Sloane JL, Stevens MC. Scalable synthesis of bryostatin 1 and analogs, adjuvant leads against latent HIV. Science (New York, N.Y.). 358: 218-223. PMID 29026042 DOI: 10.1126/Science.Aan7969 |
0.532 |
|
| 2017 |
Marsden MD, Loy BA, Wu X, Ramirez CM, Schrier AJ, Murray D, Shimizu A, Ryckbosch SM, Near KE, Chun TW, Wender PA, Zack JA. In vivo activation of latent HIV with a synthetic bryostatin analog effects both latent cell "kick" and "kill" in strategy for virus eradication. Plos Pathogens. 13: e1006575. PMID 28934369 DOI: 10.1371/Journal.Ppat.1006575 |
0.746 |
|
| 2017 |
Benner NL, Zang X, Buehler DC, Kickhoefer VA, Rome ME, Rome LH, Wender PA. Vault Nanoparticles: Chemical Modifications for Imaging and Enhanced Delivery. Acs Nano. PMID 28029784 DOI: 10.1021/Acsnano.6B07440 |
0.32 |
|
| 2016 |
Abdelnabi R, Staveness D, Near KE, Wender PA, Delang L, Neyts J, Leyssen P. Comparative analysis of the anti-chikungunya virus activity of novel bryostatin analogs confirms the existence of a PKC-independent mechanism. Biochemical Pharmacology. PMID 27664855 DOI: 10.1016/J.Bcp.2016.09.020 |
0.763 |
|
| 2016 |
McKinlay CJ, Waymouth RM, Wender PA. Cell-Penetrating, Guanidinium-Rich Oligophosphoesters: Effective and Versatile Molecular Transporters for Drug and Probe Delivery. Journal of the American Chemical Society. PMID 26900771 DOI: 10.1021/Jacs.5B13452 |
0.339 |
|
| 2016 |
Staveness D, Abdelnabi R, Near KE, Nakagawa Y, Neyts J, Delang L, Leyssen P, Wender PA. Inhibition of Chikungunya Virus-Induced Cell Death by Salicylate-Derived Bryostatin Analogues Provides Additional Evidence for a PKC-Independent Pathway. Journal of Natural Products. PMID 26900711 DOI: 10.1021/Acs.Jnatprod.5B01017 |
0.763 |
|
| 2016 |
Staveness D, Abdelnabi R, Schrier AJ, Loy BA, Verma VA, DeChristopher BA, Near KE, Neyts J, Delang L, Leyssen P, Wender PA. Simplified Bryostatin Analogues Protect Cells from Chikungunya Virus-Induced Cell Death. Journal of Natural Products. PMID 26900625 DOI: 10.1021/Acs.Jnatprod.5B01016 |
0.769 |
|
| 2015 |
Hsu HT, Trantow BM, Waymouth RM, Wender PA. Bioorthogonal Catalysis: A General Method To Evaluate Metal-Catalyzed Reactions in Real Time in Living Systems Using a Cellular Luciferase Reporter System. Bioconjugate Chemistry. PMID 26367192 DOI: 10.1021/Acs.Bioconjchem.5B00469 |
0.336 |
|
| 2015 |
Mustard TJ, Wender PA, Cheong PH. Catalytic Efficiency Is a Function of How Rhodium(I) (5 + 2) Catalysts Accommodate a Conserved Substrate Transition State Geometry: Induced Fit Model for Explaining Transition Metal Catalysis. Acs Catalysis. 5: 1758-1763. PMID 26146588 DOI: 10.1021/Cs501828E |
0.32 |
|
| 2015 |
Boudreault PL, Mattler JK, Wender PA. Studies on the regio- and diastereo-selective epoxidation of daphnanes and tiglianes. Tetrahedron Letters. 56: 3423-3427. PMID 26034334 DOI: 10.1016/J.Tetlet.2015.01.126 |
0.37 |
|
| 2015 |
Wender PA, Jeffreys MS, Raub AG. Tetramethyleneethane Equivalents: Recursive Reagents for Serialized Cycloadditions. Journal of the American Chemical Society. PMID 25961416 DOI: 10.1021/Jacs.5B04091 |
0.421 |
|
| 2015 |
Wender PA, Quiroz RV, Stevens MC. Function through synthesis-informed design. Accounts of Chemical Research. 48: 752-60. PMID 25742599 DOI: 10.1021/Acs.Accounts.5B00004 |
0.583 |
|
| 2015 |
Loy BA, Lesser AB, Staveness D, Billingsley KL, Cegelski L, Wender PA. Toward a biorelevant structure of protein kinase C bound modulators: design, synthesis, and evaluation of labeled bryostatin analogues for analysis with rotational echo double resonance NMR spectroscopy. Journal of the American Chemical Society. 137: 3678-85. PMID 25710634 DOI: 10.1021/Jacs.5B00886 |
0.718 |
|
| 2015 |
Wender PA, Huttner MA, Staveness D, Vargas JR, Xu AF. Guanidinium-rich, glycerol-derived oligocarbonates: a new class of cell-penetrating molecular transporters that complex, deliver, and release siRNA. Molecular Pharmaceutics. 12: 742-50. PMID 25588140 DOI: 10.1021/Mp500581R |
0.375 |
|
| 2014 |
Wender PA, Axtman AD, Golden JE, Kee JM, Sirois LE, Quiroz RV, Stevens MC. Function through bio-inspired, synthesis-informed design: step-economical syntheses of designed kinase inhibitors†Dedicated to Max Malacria, a friend and scholar whose science and creative contributions to step-economical synthesis have inspired us all and moved the field closer to the ideal.‡Electronic supplementary information (ESI) available: Synthetic procedures and spectral data. See DOI: 10.1039/c4qo00228hClick here for additional data file. Organic Chemistry Frontiers : An International Journal of Organic Chemistry / Royal Society of Chemistry. 1: 1166-1171. PMID 25632347 DOI: 10.1039/C4Qo00228H |
0.718 |
|
| 2014 |
Hong X, Stevens MC, Liu P, Wender PA, Houk KN. Reactivity and chemoselectivity of allenes in Rh(I)-catalyzed intermolecular (5 + 2) cycloadditions with vinylcyclopropanes: allene-mediated rhodacycle formation can poison Rh(I)-catalyzed cycloadditions. Journal of the American Chemical Society. 136: 17273-83. PMID 25379606 DOI: 10.1021/Ja5098308 |
0.566 |
|
| 2014 |
Wender PA, Staveness D. Improved protein kinase C affinity through final step diversification of a simplified salicylate-derived bryostatin analog scaffold. Organic Letters. 16: 5140-3. PMID 25238640 DOI: 10.1021/Ol502492B |
0.354 |
|
| 2014 |
Wender PA, Nakagawa Y, Near KE, Staveness D. Computer-guided design, synthesis, and protein kinase C affinity of a new salicylate-based class of bryostatin analogs. Organic Letters. 16: 5136-9. PMID 25238583 DOI: 10.1021/Ol502491F |
0.784 |
|
| 2014 |
Wender PA, Inagaki F, Pfaffenbach M, Stevens MC. Propargyltrimethylsilanes as allene equivalents in transition metal-catalyzed [5 + 2] cycloadditions. Organic Letters. 16: 2923-5. PMID 24819093 DOI: 10.1021/Ol501114Q |
0.573 |
|
| 2014 |
Wender PA, Fournogerakis DN, Jeffreys MS, Quiroz RV, Inagaki F, Pfaffenbach M. Structural complexity through multicomponent cycloaddition cascades enabled by dual-purpose, reactivity regenerating 1,2,3-triene equivalents. Nature Chemistry. 6: 448-52. PMID 24755598 DOI: 10.1038/Nchem.1917 |
0.388 |
|
| 2014 |
Wender PA. Toward the ideal synthesis and molecular function through synthesis-informed design. Natural Product Reports. 31: 433-40. PMID 24589860 DOI: 10.1039/C4Np00013G |
0.357 |
|
| 2014 |
Wender PA, Donnelly AC, Loy BA, Near KE, Staveness D. Rethinking the Role of Natural Products: Function-Oriented Synthesis, Bryostatin, and Bryologs Natural Products in Medicinal Chemistry. 473-544. DOI: 10.1002/9783527676545.ch14 |
0.748 |
|
| 2013 |
Wender PA, Billingsley KL. Lead Diversification through a Prins-Driven Macrocyclization Strategy: Application to C13-Diversified Bryostatin Analogues. Synthesis. 45: 1815-1824. PMID 24672140 DOI: 10.1055/S-0033-1338860 |
0.748 |
|
| 2013 |
Wender PA. Toward the Ideal Synthesis and Transformative Therapies: The Roles of Step Economy and Function Oriented Synthesis. Tetrahedron. 69: 7529-7550. PMID 23956471 DOI: 10.1016/J.Tet.2013.06.004 |
0.321 |
|
| 2013 |
Beans EJ, Fournogerakis D, Gauntlett C, Heumann LV, Kramer R, Marsden MD, Murray D, Chun TW, Zack JA, Wender PA. Highly potent, synthetically accessible prostratin analogs induce latent HIV expression in vitro and ex vivo. Proceedings of the National Academy of Sciences of the United States of America. 110: 11698-703. PMID 23812750 DOI: 10.1073/Pnas.1302634110 |
0.767 |
|
| 2013 |
Stanzl EG, Trantow BM, Vargas JR, Wender PA. Fifteen years of cell-penetrating, guanidinium-rich molecular transporters: basic science, research tools, and clinical applications. Accounts of Chemical Research. 46: 2944-54. PMID 23697862 DOI: 10.1021/Ar4000554 |
0.302 |
|
| 2013 |
Ogawa Y, Painter PP, Tantillo DJ, Wender PA. Mechanistic and computational studies of exocyclic stereocontrol in the synthesis of bryostatin-like cis-2,6-disubstituted 4-alkylidenetetrahydropyrans by Prins cyclization. The Journal of Organic Chemistry. 78: 104-15. PMID 23121542 DOI: 10.1021/Jo301953H |
0.309 |
|
| 2012 |
Geihe EI, Cooley CB, Simon JR, Kiesewetter MK, Edward JA, Hickerson RP, Kaspar RL, Hedrick JL, Waymouth RM, Wender PA. Designed guanidinium-rich amphipathic oligocarbonate molecular transporters complex, deliver and release siRNA in cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 13171-6. PMID 22847412 DOI: 10.1073/Pnas.1211361109 |
0.647 |
|
| 2012 |
Wender PA, Cooley CB, Geihe EI. Beyond Cell Penetrating Peptides: Designed Molecular Transporters. Drug Discovery Today. Technologies. 9: e49-e55. PMID 22712022 DOI: 10.1016/J.Ddtec.2011.07.004 |
0.629 |
|
| 2012 |
Xu X, Liu P, Lesser A, Sirois LE, Wender PA, Houk KN. Ligand effects on rates and regioselectivities of Rh(I)-catalyzed (5 + 2) cycloadditions: a computational study of cyclooctadiene and dinaphthocyclooctatetraene as ligands. Journal of the American Chemical Society. 134: 11012-25. PMID 22668243 DOI: 10.1021/Ja3041724 |
0.339 |
|
| 2012 |
Wender PA, Galliher WC, Bhat NM, Pillow TH, Bieber MM, Teng NN. Taxol-oligoarginine conjugates overcome drug resistance in-vitro in human ovarian carcinoma. Gynecologic Oncology. 126: 118-23. PMID 22484398 DOI: 10.1016/J.Ygyno.2012.03.049 |
0.637 |
|
| 2012 |
DeChristopher BA, Fan AC, Felsher DW, Wender PA. "Picolog," a synthetically-available bryostatin analog, inhibits growth of MYC-induced lymphoma in vivo. Oncotarget. 3: 58-66. PMID 22308267 DOI: 10.18632/Oncotarget.438 |
0.319 |
|
| 2012 |
Wender PA, Lesser AB, Sirois LE. Rhodium dinaphthocyclooctatetraene complexes: synthesis, characterization and catalytic activity in [5+2] cycloadditions. Angewandte Chemie (International Ed. in English). 51: 2736-40. PMID 22298411 DOI: 10.1002/Anie.201108270 |
0.353 |
|
| 2012 |
Wender PA, Lesser AB, Sirois LE. The Preparation of Cyclohept‐4‐Enones by Rhodium‐Catalyzed Intermolecular [5+2] Cycloaddition Organic Syntheses. 109-120. DOI: 10.1002/0471264229.Os088.11 |
0.304 |
|
| 2011 |
Wender PA, Loy BA, Schrier AJ. Translating Nature's Library: The Bryostatins and Function-Oriented Synthesis. Israel Journal of Chemistry. 51: 453-472. PMID 22661768 DOI: 10.1002/Ijch.201100020 |
0.39 |
|
| 2011 |
Wender PA, Reuber J. Function Oriented Synthesis: Preparation and Initial Biological Evaluation of New A-Ring-Modified Bryologs. Tetrahedron. 67: 9998-10005. PMID 22247574 DOI: 10.1016/J.Tet.2011.09.058 |
0.405 |
|
| 2011 |
Wender PA, Buschmann N, Cardin NB, Jones LR, Kan C, Kee JM, Kowalski JA, Longcore KE. Gateway synthesis of daphnane congeners and their protein kinase C affinities and cell-growth activities. Nature Chemistry. 3: 615-9. PMID 21778981 DOI: 10.1038/Nchem.1074 |
0.814 |
|
| 2011 |
Wender PA, Schrier AJ. Total synthesis of bryostatin 9. Journal of the American Chemical Society. 133: 9228-31. PMID 21618969 DOI: 10.1021/Ja203034K |
0.37 |
|
| 2011 |
Wender PA, Baryza JL, Brenner SE, DeChristopher BA, Loy BA, Schrier AJ, Verma VA. Design, synthesis, and evaluation of potent bryostatin analogs that modulate PKC translocation selectivity. Proceedings of the National Academy of Sciences of the United States of America. 108: 6721-6. PMID 21415363 DOI: 10.1073/Pnas.1015270108 |
0.815 |
|
| 2010 |
Liu P, Sirois LE, Cheong PH, Yu ZX, Hartung IV, Rieck H, Wender PA, Houk KN. Electronic and steric control of regioselectivities in Rh(I)-catalyzed (5 + 2) cycloadditions: experiment and theory. Journal of the American Chemical Society. 132: 10127-35. PMID 20586494 DOI: 10.1021/Ja103253D |
0.357 |
|
| 2010 |
Wender PA, Sirois LE, Stemmler RT, Williams TJ. Highly efficient, facile, room temperature intermolecular [5 + 2] cycloadditions catalyzed by cationic rhodium(I): one step to cycloheptenes and their libraries. Organic Letters. 12: 1604-7. PMID 20196579 DOI: 10.1021/Ol100337M |
0.498 |
|
| 2010 |
Wender PA, Stemmler RT, Sirois LE. A metal-catalyzed intermolecular [5+2] cycloaddition/Nazarov cyclization sequence and cascade. Journal of the American Chemical Society. 132: 2532-3. PMID 20141136 DOI: 10.1021/Ja910696X |
0.409 |
|
| 2010 |
Wender PA, Stemmler RT, Sirois LE. Rhodium-Catalyzed [5+2] Cycloaddition-NazarovCyclization Strategy Synfacts. 2010: 562-562. DOI: 10.1055/S-0029-1219702 |
0.36 |
|
| 2010 |
Bruckner R, Harmata M, Wender PA. Organic mechanisms: Reactions, stereochemistry and synthesis Organic Mechanisms: Reactions, Stereochemistry and Synthesis. 1-855. DOI: 10.1007/978-3-642-03651-4 |
0.519 |
|
| 2010 |
Croatt MP, Wender PA. The diene effect: The design, development, and Mechanistic investigation of metal-catalyzed diene-yne, diene-ene, and diene-allene [2+2+1] cycloaddition reactions European Journal of Organic Chemistry. 19-32. DOI: 10.1002/Ejoc.200900929 |
0.751 |
|
| 2010 |
Wender PA, Bi FC, Gamber GG, Gosselin F, Hubbard RD, Scanio MJC, Sun R, Williams TJ, Zhang L. ChemInform Abstract: Toward the Ideal Synthesis: New Transition Metal catalyzed Reactions Inspired by Novel Medicinal Leads Cheminform. 33: no-no. DOI: 10.1002/chin.200241295 |
0.816 |
|
| 2010 |
Wender PA, Love JA. ChemInform Abstract: The Synthesis of Seven-Membered Rings: General Strategies and the Design and Development of a New Class of Cycloaddition Reactions Cheminform. 30: no-no. DOI: 10.1002/chin.199937294 |
0.586 |
|
| 2010 |
WENDER PA, SMITH TE. ChemInform Abstract: Transition Metal Catalyzed Intramolecular (4 + 2) Cycloadditions: A Novel Method for the Assembly of Nitrogen Heterocycles and Its Application to Yohimban Alkaloid Synthesis. Cheminform. 27: no-no. DOI: 10.1002/chin.199627047 |
0.484 |
|
| 2010 |
WENDER PA, WESSJOHANN LA, PESCHKE B, RAWLINS DB. ChemInform Abstract: The Pinene Path to Taxol: Readily Accessible A-Ring Building Blocks Based on Novel Alkyl- and Alkenyllithium Reagents with Internal Carbonyl Groups. Cheminform. 27: no-no. DOI: 10.1002/chin.199603197 |
0.457 |
|
| 2010 |
WENDER PA, GLASS TE. ChemInform Abstract: Pinene Approach to Taxanes. Part 2. Development of a Versatile C9, C10 Linker. Cheminform. 26: no-no. DOI: 10.1002/chin.199540190 |
0.532 |
|
| 2010 |
WENDER PA, SMITH TE. ChemInform Abstract: Transition Metal Catalyzed Intramolecular (4 + 2) Cycloadditions: Initial Studies on Stereochemistry and on Steroid and Vitamin D Analogue Syntheses. Cheminform. 26: no-no. DOI: 10.1002/chin.199540049 |
0.425 |
|
| 2010 |
WENDER PA, TAKAHASHI H, WITULSKI B. ChemInform Abstract: Transition Metal Catalyzed (5 + 2) Cycloadditions of Vinylcyclopropanes and Alkynes: A Homologue of the Diels-Alder Reaction for the Synthesis of Seven-Membered Rings. Cheminform. 26: no-no. DOI: 10.1002/chin.199535047 |
0.302 |
|
| 2010 |
WENDER PA, BECKHAM S, MOHLER DL. ChemInform Abstract: The Intramolecular Addition of Silylated Alkynes to Aldehydes: Methodology for the Construction of Cyclic Enediynes and Its Application to Dynemicin Analogues. Cheminform. 26: no-no. DOI: 10.1002/chin.199521289 |
0.693 |
|
| 2010 |
WENDER PA, ZERCHER CK, BECKHAM S, HAUBOLD E. ChemInform Abstract: A Photochemically Triggered DNA Cleaving Agent: Synthesis, Mechanistic and DNA Cleavage Studies on a New Analogue of the Antitumor Antibiotic Dynemicin. Cheminform. 25: no-no. DOI: 10.1002/chin.199411279 |
0.619 |
|
| 2010 |
WENDER PA, ZERCHER CK. ChemInform Abstract: Studies on DNA-Cleaving Agents: Synthesis of a Functional Dynemicin Analogue. Cheminform. 22: no-no. DOI: 10.1002/chin.199130287 |
0.629 |
|
| 2009 |
Cooley CB, Trantow BM, Nederberg F, Kiesewetter MK, Hedrick JL, Waymouth RM, Wender PA. Oligocarbonate molecular transporters: oligomerization-based syntheses and cell-penetrating studies. Journal of the American Chemical Society. 131: 16401-3. PMID 19860416 DOI: 10.1021/Ja907363K |
0.634 |
|
| 2009 |
Lewis CA, Longcore KE, Miller SJ, Wender PA. An approach to the site-selective diversification of apoptolidin A with peptide-based catalysts. Journal of Natural Products. 72: 1864-9. PMID 19769383 DOI: 10.1021/Np9004932 |
0.339 |
|
| 2009 |
Wender PA, Christy JP, Lesser AB, Gieseler MT. The synthesis of highly substituted cyclooctatetraene scaffolds by metal-catalyzed [2+2+2+2] cycloadditions: studies on regioselectivity, dynamic properties, and metal chelation. Angewandte Chemie (International Ed. in English). 48: 7687-90. PMID 19739178 DOI: 10.1002/Anie.200903859 |
0.351 |
|
| 2009 |
Shaha SP, Tomic J, Shi Y, Pham T, Mero P, White D, He L, Baryza JL, Wender PA, Booth JW, Spaner DE. Prolonging microtubule dysruption enhances the immunogenicity of chronic lymphocytic leukaemia cells. Clinical and Experimental Immunology. 158: 186-98. PMID 19737143 DOI: 10.1111/J.1365-2249.2009.04003.X |
0.725 |
|
| 2009 |
Wender PA, Miller BL. Synthesis at the molecular frontier. Nature. 460: 197-201. PMID 19587760 DOI: 10.1038/460197A |
0.553 |
|
| 2009 |
Wender PA, Strand D. Cyclocarboamination of alkynes with aziridines: synthesis of 2,3-dihydropyrroles by a catalyzed formal [3 + 2] cycloaddition. Journal of the American Chemical Society. 131: 7528-9. PMID 19489638 DOI: 10.1021/Ja901799S |
0.605 |
|
| 2009 |
Wender PA, Croatt MP, Kühn B. Rhodium(I)-catalyzed [2+2], [2+2+2], and [2+2+2+2] cycloadditions of dienes or alkynes with a bis-ene Organometallics. 28: 5841-5844. DOI: 10.1021/Om9007373 |
0.731 |
|
| 2008 |
Dubikovskaya EA, Thorne SH, Pillow TH, Contag CH, Wender PA. Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters. Proceedings of the National Academy of Sciences of the United States of America. 105: 12128-33. PMID 18713866 DOI: 10.1073/Pnas.0805374105 |
0.645 |
|
| 2008 |
Mooberry SL, Hilinski MK, Clark EA, Wender PA. Function-oriented synthesis: biological evaluation of laulimalide analogues derived from a last step cross metathesis diversification strategy. Molecular Pharmaceutics. 5: 829-38. PMID 18662015 DOI: 10.1021/Mp800043N |
0.768 |
|
| 2008 |
Wender PA, Verma VA. The design, synthesis, and evaluation of C7 diversified bryostatin analogs reveals a hot spot for PKC affinity. Organic Letters. 10: 3331-4. PMID 18588309 DOI: 10.1021/Ol801235H |
0.383 |
|
| 2008 |
Wender PA, Dechristopher BA, Schrier AJ. Efficient synthetic access to a new family of highly potent bryostatin analogues via a Prins-driven macrocyclization strategy. Journal of the American Chemical Society. 130: 6658-9. PMID 18452292 DOI: 10.1021/Ja8015632 |
0.437 |
|
| 2008 |
Wender PA, Kee JM, Warrington JM. Practical synthesis of prostratin, DPP, and their analogs, adjuvant leads against latent HIV. Science (New York, N.Y.). 320: 649-52. PMID 18451298 DOI: 10.1126/Science.1154690 |
0.644 |
|
| 2008 |
Yu ZX, Cheong PH, Liu P, Legault CY, Wender PA, Houk KN. Origins of differences in reactivities of alkenes, alkynes, and allenes in [Rh(CO)2Cl]2-catalyzed (5 + 2) cycloaddition reactions with vinylcyclopropanes. Journal of the American Chemical Society. 130: 2378-9. PMID 18251468 DOI: 10.1021/Ja076444D |
0.365 |
|
| 2008 |
Wender PA, Galliher WC, Goun EA, Jones LR, Pillow TH. The design of guanidinium-rich transporters and their internalization mechanisms. Advanced Drug Delivery Reviews. 60: 452-72. PMID 18164781 DOI: 10.1016/J.Addr.2007.10.016 |
0.78 |
|
| 2008 |
Wender PA, Verma VA, Paxton TJ, Pillow TH. Function-oriented synthesis, step economy, and drug design. Accounts of Chemical Research. 41: 40-9. PMID 18159936 DOI: 10.1021/Ar700155P |
0.708 |
|
| 2008 |
Wender P, DeChristopher B, Schrier A. Synthesis of Bryostatin Analogues Synfacts. 2008: 1139-1139. DOI: 10.1055/S-0028-1083409 |
0.399 |
|
| 2007 |
Wender PA, Christy JP. Nickel(0)-catalyzed [2 + 2 + 2 + 2] cycloadditions of terminal diynes for the synthesis of substituted cyclooctatetraenes. Journal of the American Chemical Society. 129: 13402-3. PMID 17929819 DOI: 10.1021/Ja0763044 |
0.398 |
|
| 2007 |
Wang Y, Wang J, Su J, Huang F, Jiao L, Liang Y, Yang D, Zhang S, Wender PA, Yu ZX. A computationally designed Rh(I)-catalyzed two-component [5+2+1] cycloaddition of ene-vinylcyclopropanes and CO for the synthesis of cyclooctenones. Journal of the American Chemical Society. 129: 10060-1. PMID 17655302 DOI: 10.1021/Ja072505W |
0.366 |
|
| 2007 |
Wender PA, Goun EA, Jones LR, Pillow TH, Rothbard JB, Shinde R, Contag CH. Real-time analysis of uptake and bioactivatable cleavage of luciferin-transporter conjugates in transgenic reporter mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 10340-5. PMID 17563383 DOI: 10.1073/Pnas.0703919104 |
0.779 |
|
| 2007 |
Wender PA, D'Angelo N, Elitzin VI, Ernst M, Jackson-Ugueto EE, Kowalski JA, McKendry S, Rehfeuter M, Sun R, Voigtlaender D. Function-oriented synthesis: studies aimed at the synthesis and mode of action of 1alpha-alkyldaphnane analogues. Organic Letters. 9: 1829-32. PMID 17408281 DOI: 10.1021/Ol0705649 |
0.805 |
|
| 2007 |
Gómez FJ, Kamber NE, Deschamps NM, Cole AP, Wender PA, Waymouth RM. N-alkoxyimidazolylidene transition-metal complexes: Application to [5+2] and [4+2] cycloaddition reactions Organometallics. 26: 4541-4545. DOI: 10.1021/Om700493Y |
0.788 |
|
| 2007 |
Wender PA, Croatt MP, Deschamps NM. C-C bond formation (part 1) by addition reactions: Higher-order cycloadditions Comprehensive Organometallic Chemistry Iii. 10: 603-647. |
0.789 |
|
| 2006 |
Wender PA, Paxton TJ, Williams TJ. Cyclopentadienone synthesis by rhodium(I)-catalyzed [3 + 2] cycloaddition reactions of cyclopropenones and alkynes. Journal of the American Chemical Society. 128: 14814-5. PMID 17105285 DOI: 10.1021/Ja065868P |
0.541 |
|
| 2006 |
Wender PA, Bi FC, Buschmann N, Gosselin F, Kan C, Kee JM, Ohmura H. Studies on oxidopyrylium [5+2] cycloadditions: toward a general synthetic route to the C12-hydroxydaphnetoxins. Organic Letters. 8: 5373-6. PMID 17078721 DOI: 10.1021/Ol062234E |
0.794 |
|
| 2006 |
Wender PA, Horan JC, Verma VA. Total synthesis and initial biological evaluation of new B-ring-modified bryostatin analogs. Organic Letters. 8: 5299-302. PMID 17078702 DOI: 10.1021/Ol0620904 |
0.791 |
|
| 2006 |
Wender PA, Horan JC. Synthesis and PKC binding of a new class of a-ring diversifiable bryostatin analogues utilizing a double asymmetric hydrogenation and cross-coupling strategy. Organic Letters. 8: 4581-4. PMID 16986955 DOI: 10.1021/Ol0618149 |
0.793 |
|
| 2006 |
Goun EA, Pillow TH, Jones LR, Rothbard JB, Wender PA. Molecular transporters: synthesis of oligoguanidinium transporters and their application to drug delivery and real-time imaging. Chembiochem : a European Journal of Chemical Biology. 7: 1497-515. PMID 16972294 DOI: 10.1002/Cbic.200600171 |
0.779 |
|
| 2006 |
Wender PA, Hilinski MK, Skaanderup PR, Soldermann NG, Mooberry SL. Pharmacophore mapping in the laulimalide series: total synthesis of a vinylogue for a late-stage metathesis diversification strategy. Organic Letters. 8: 4105-8. PMID 16928085 DOI: 10.1021/Ol061619U |
0.77 |
|
| 2006 |
Clark EA, Hills PM, Davidson BS, Wender PA, Mooberry SL. Laulimalide and synthetic laulimalide analogues are synergistic with paclitaxel and 2-methoxyestradiol. Molecular Pharmaceutics. 3: 457-67. PMID 16889440 DOI: 10.1021/Mp060016H |
0.327 |
|
| 2006 |
Jones LR, Goun EA, Shinde R, Rothbard JB, Contag CH, Wender PA. Releasable luciferin-transporter conjugates: tools for the real-time analysis of cellular uptake and release. Journal of the American Chemical Society. 128: 6526-7. PMID 16704230 DOI: 10.1021/Ja0586283 |
0.721 |
|
| 2006 |
Goun EA, Shinde R, Dehnert KW, Adams-Bond A, Wender PA, Contag CH, Franc BL. Intracellular cargo delivery by an octaarginine transporter adapted to target prostate cancer cells through cell surface protease activation. Bioconjugate Chemistry. 17: 787-96. PMID 16704219 DOI: 10.1021/Bc0503216 |
0.724 |
|
| 2006 |
Wender PA, Haustedt LO, Lim J, Love JA, Williams TJ, Yoon JY. Asymmetric catalysis of the [5 + 2] cycloaddition reaction of vinylcyclopropanes and pi-systems. Journal of the American Chemical Society. 128: 6302-3. PMID 16683779 DOI: 10.1021/Ja058590U |
0.648 |
|
| 2006 |
Wender PA, Deschamps NM, Sun R. RhI-catalyzed C-C bond activation: seven-membered ring synthesis by a [6+1] carbonylative ring-expansion reaction of allenylcyclobutanes. Angewandte Chemie (International Ed. in English). 45: 3957-60. PMID 16683295 DOI: 10.1002/Anie.200600806 |
0.81 |
|
| 2006 |
Wender PA, Verma VA. Design, synthesis, and biological evaluation of a potent, PKC selective, B-ring analog of bryostatin. Organic Letters. 8: 1893-6. PMID 16623578 DOI: 10.1021/Ol060457Z |
0.391 |
|
| 2006 |
Wender PA, Christy JP. Rhodium(I)-catalyzed [4+2+2] cycloadditions of 1,3-dienes, alkenes, and alkynes for the synthesis of cyclooctadienes. Journal of the American Chemical Society. 128: 5354-5. PMID 16620102 DOI: 10.1021/Ja060878B |
0.427 |
|
| 2006 |
Wender PA, Hilinski MK, Soldermann N, Mooberry SL. Total synthesis and biological evaluation of 11-desmethyllaulimalide, a highly potent simplified laulimalide analogue. Organic Letters. 8: 1507-10. PMID 16562928 DOI: 10.1021/Ol060233G |
0.781 |
|
| 2006 |
Wender PA, Croatt MP, Deschamps NM. Metal-catalyzed [2+2+1] cycloadditions of 1,3-dienes, allenes, and CO. Angewandte Chemie (International Ed. in English). 45: 2459-62. PMID 16526073 DOI: 10.1002/Anie.200600300 |
0.818 |
|
| 2006 |
Wender PA, Jankowski OD, Longcore K, Tabet EA, Seto H, Tomikawa T. Correlation of F0F1-ATPase inhibition and antiproliferative activity of apoptolidin analogues. Organic Letters. 8: 589-92. PMID 16468718 DOI: 10.1021/Ol052800Q |
0.778 |
|
| 2006 |
Wender P, Haustedt L, Lim J, Love J, Williams T, Yoon J. Asymmetric [5+2] Cycloaddition of Vinylcyclopropanes and π-Systems Synfacts. 2006: 0809-0809. DOI: 10.1055/S-2006-942016 |
0.719 |
|
| 2006 |
Wender PA, Croatt MP, Witulski B. New reactions and step economy: the total synthesis of (±)-salsolene oxide based on the type II transition metal-catalyzed intramolecular [4+4] cycloaddition Tetrahedron. 62: 7505-7511. DOI: 10.1016/J.Tet.2006.02.085 |
0.722 |
|
| 2006 |
Wender PA, Baryza JL, Hilinski MK, Horan JC, Kan C, Verma VA. Beyond Natural Products: Synthetic Analogues of Bryostatin 1 Drug Discovery Research: New Frontiers in the Post-Genomic Era. 125-162. DOI: 10.1002/9780470131862.ch6 |
0.773 |
|
| 2006 |
Rothbard JB, Jessop TC, Wender PA. Molecular understanding of cellular uptake by arginine-rich cell penetrating peptides Acs Symposium Series. 923: 166-181. |
0.722 |
|
| 2005 |
Statsuk AV, Bai R, Baryza JL, Verma VA, Hamel E, Wender PA, Kozmin SA. Actin is the primary cellular receptor of bistramide A. Nature Chemical Biology. 1: 383-8. PMID 16372404 DOI: 10.1038/Nchembio748 |
0.73 |
|
| 2005 |
Wender PA, Kreider E, Pelkey ET, Rothbard J, Vandeusen CL. Dendrimeric molecular transporters: synthesis and evaluation of tunable polyguanidino dendrimers that facilitate cellular uptake. Organic Letters. 7: 4815-8. PMID 16235896 DOI: 10.1021/Ol051496Y |
0.797 |
|
| 2005 |
Wender PA, Sukopp M, Longcore K. Apoptolidins B and C: isolation, structure determination, and biological activity. Organic Letters. 7: 3025-8. PMID 15987196 DOI: 10.1021/Ol051074O |
0.345 |
|
| 2005 |
Wender PA, Clarke MO, Horan JC. Role of the A-ring of bryostatin analogues in PKC binding: synthesis and initial biological evaluation of new A-ring-modified bryologs. Organic Letters. 7: 1995-8. PMID 15876038 DOI: 10.1021/Ol0504650 |
0.816 |
|
| 2005 |
Wegner HA, de Meijere A, Wender PA. Transition metal-catalyzed intermolecular [5+2] and [5+2+1] cycloadditions of allenes and vinylcyclopropanes. Journal of the American Chemical Society. 127: 6530-1. PMID 15869263 DOI: 10.1021/Ja043671W |
0.626 |
|
| 2005 |
Wender PA, Baryza JL. Identification of a tunable site in bryostatin analogs: C20 Bryologs through late stage diversification. Organic Letters. 7: 1177-80. PMID 15760168 DOI: 10.1021/Ol0501931 |
0.738 |
|
| 2005 |
Wender PA, Gamber GG, Hubbard RD, Pham SM, Zhang L. Multicomponent cycloadditions: the four-component [5+1+2+1] cycloaddition of vinylcyclopropanes, alkynes, and CO. Journal of the American Chemical Society. 127: 2836-7. PMID 15740103 DOI: 10.1021/Ja042728B |
0.81 |
|
| 2005 |
Rothbard JB, Jessop TC, Wender PA. Adaptive translocation: the role of hydrogen bonding and membrane potential in the uptake of guanidinium-rich transporters into cells. Advanced Drug Delivery Reviews. 57: 495-504. PMID 15722160 DOI: 10.1016/J.Addr.2004.10.003 |
0.737 |
|
| 2005 |
Wender PA, Hilinski MK, Mayweg AV. Late-stage intermolecular CH activation for lead diversification: a highly chemoselective oxyfunctionalization of the C-9 position of potent bryostatin analogues. Organic Letters. 7: 79-82. PMID 15624982 DOI: 10.1021/Ol047859W |
0.734 |
|
| 2005 |
Hammond C, Shi Y, Mena J, Tomic J, Cervi D, He L, Millar AE, Debenedette M, Schuh AC, Baryza JL, Wender PA, Radvanyi L, Spaner DE. Effect of serum and antioxidants on the immunogenicity of protein kinase C-activated chronic lymphocytic leukemia cells. Journal of Immunotherapy (Hagerstown, Md. : 1997). 28: 28-39. PMID 15614042 DOI: 10.1097/00002371-200501000-00004 |
0.723 |
|
| 2005 |
Wender PA, Deschamps NM, Sun R. Rh(I)-catalyzed cleavage of unactivated C-O bonds - Carbonylative rearrangement reactions of allenyl ethers to 2-carboalkoxy-1,3-dienes Canadian Journal of Chemistry. 83: 838-842. DOI: 10.1139/V05-085 |
0.807 |
|
| 2005 |
Wender PA, Gamber GG, Williams TJ. Rhodium(I)-Catalyzed [5+2], [6+2], and [5+2+1] Cycloadditions: New Reactions for Organic Synthesis Modern Rhodium-Catalyzed Organic Reactions. 263-299. DOI: 10.1002/3527604693.ch13 |
0.805 |
|
| 2004 |
Wender PA, Baryza JL, Brenner SE, Clarke MO, Craske ML, Horan JC, Meyer T. Function oriented synthesis: the design, synthesis, PKC binding and translocation activity of a new bryostatin analog. Current Drug Discovery Technologies. 1: 1-11. PMID 16472215 DOI: 10.2174/1570163043484888 |
0.808 |
|
| 2004 |
Stone JC, Stang SL, Zheng Y, Dower NA, Brenner SE, Baryza JL, Wender PA. Synthetic bryostatin analogues activate the RasGRP1 signaling pathway. Journal of Medicinal Chemistry. 47: 6638-44. PMID 15588099 DOI: 10.1021/Jm0495069 |
0.781 |
|
| 2004 |
Baryza JL, Brenner SE, Craske ML, Meyer T, Wender PA. Simplified analogs of bryostatin with anticancer activity display greater potency for translocation of PKCdelta-GFP. Chemistry & Biology. 11: 1261-7. PMID 15380186 DOI: 10.1016/J.Chembiol.2004.06.014 |
0.786 |
|
| 2004 |
Rothbard JB, Jessop TC, Lewis RS, Murray BA, Wender PA. Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells. Journal of the American Chemical Society. 126: 9506-7. PMID 15291531 DOI: 10.1021/Ja0482536 |
0.75 |
|
| 2004 |
Yu ZX, Wender PA, Houk KN. On the mechanism of [Rh(CO)2Cl]2-catalyzed intermolecular (5 + 2) reactions between vinylcyclopropanes and alkynes. Journal of the American Chemical Society. 126: 9154-5. PMID 15281784 DOI: 10.1021/Ja048739M |
0.339 |
|
| 2004 |
Wender PA, Deschamps NM, Williams TJ. Intermolecular dienyl Pauson-Khand reaction. Angewandte Chemie (International Ed. in English). 43: 3076-9. PMID 15188486 DOI: 10.1002/Anie.200454117 |
0.788 |
|
| 2004 |
Shi Kam NW, Jessop TC, Wender PA, Dai H. Nanotube molecular transporters: internalization of carbon nanotube-protein conjugates into Mammalian cells. Journal of the American Chemical Society. 126: 6850-1. PMID 15174838 DOI: 10.1021/Ja0486059 |
0.75 |
|
| 2004 |
Mooberry SL, Randall-Hlubek DA, Leal RM, Hegde SG, Hubbard RD, Zhang L, Wender PA. Microtubule-stabilizing agents based on designed laulimalide analogues. Proceedings of the National Academy of Sciences of the United States of America. 101: 8803-8. PMID 15161976 DOI: 10.1073/Pnas.0402759101 |
0.342 |
|
| 2004 |
Wender PA, Croatt MP, Deschamps NM. Rhodium(I)-catalyzed [2+2+1] cycloadditions of 1,3-dienes, alkenes, and CO. Journal of the American Chemical Society. 126: 5948-9. PMID 15137743 DOI: 10.1021/Ja0489487 |
0.811 |
|
| 2003 |
Wender PA, Koehler MF, Sendzik M. A new synthetic approach to the C ring of known as well as novel bryostatin analogues. Organic Letters. 5: 4549-52. PMID 14627380 DOI: 10.1021/Ol0355332 |
0.408 |
|
| 2003 |
Samuel BU, Hearn B, Mack D, Wender P, Rothbard J, Kirisits MJ, Mui E, Wernimont S, Roberts CW, Muench SP, Rice DW, Prigge ST, Law AB, McLeod R. Delivery of antimicrobials into parasites. Proceedings of the National Academy of Sciences of the United States of America. 100: 14281-6. PMID 14623959 DOI: 10.1073/Pnas.2436169100 |
0.709 |
|
| 2003 |
Wender PA, Hegde SG, Hubbard RD, Zhang L, Mooberry SL. Synthesis and biological evaluation of (-)-laulimalide analogues. Organic Letters. 5: 3507-9. PMID 12967311 DOI: 10.1021/Ol035339F |
0.371 |
|
| 2003 |
Kirschberg TA, VanDeusen CL, Rothbard JB, Yang M, Wender PA. Arginine-based molecular transporters: the synthesis and chemical evaluation of releasable taxol-transporter conjugates. Organic Letters. 5: 3459-62. PMID 12967299 DOI: 10.1021/Ol035234C |
0.785 |
|
| 2003 |
Wender PA, Jankowski OD, Tabet EA, Seto H. Facile synthetic access to and biological evaluation of the macrocyclic core of apoptolidin. Organic Letters. 5: 2299-302. PMID 12816433 DOI: 10.1021/Ol0346335 |
0.792 |
|
| 2003 |
Wender PA, Deschamps NM, Gamber GG. The dienyl Pauson-Khand reaction. Angewandte Chemie (International Ed. in English). 42: 1853-7. PMID 12722081 DOI: 10.1002/Anie.200350949 |
0.782 |
|
| 2003 |
Wright LR, Rothbard JB, Wender PA. Guanidinium rich peptide transporters and drug delivery. Current Protein & Peptide Science. 4: 105-24. PMID 12678850 DOI: 10.2174/1389203033487252 |
0.692 |
|
| 2003 |
Wender PA, Jankowski OD, Tabet EA, Seto H. Toward a structure-activity relationship for apoptolidin: selective functionalization of the hydroxyl group array. Organic Letters. 5: 487-90. PMID 12583750 DOI: 10.1021/Ol027366W |
0.791 |
|
| 2003 |
Wender PA, Mayweg AV, VanDeusen CL. A concise, selective synthesis of the polyketide spacer domain of a potent bryostatin analogue. Organic Letters. 5: 277-9. PMID 12556171 DOI: 10.1021/Ol0272390 |
0.806 |
|
| 2003 |
Wender PA, Baryza JL, Brenner SE, Clarke MO, Gamber GG, Horan JC, Jessop TC, Kan C, Pattabiraman K, Williams TJ. Inspirations from nature. New reactions, new therapeutic leads, and new drug delivery systems Pure and Applied Chemistry. 75: 143-155. DOI: 10.1351/Pac200375020143 |
0.803 |
|
| 2003 |
Wender PA, Love JA, Williams TJ. Rhodium-catalyzed [5+2] cycloaddition reactions in water Synlett. 1295-1298. DOI: 10.1055/S-2003-40357 |
0.621 |
|
| 2003 |
Wender PA, White AW, McDonald FE. Spiroannelation via Organobis(Cuprates): 9,9‐Dimethylspiro[4.5]Decan‐7‐One Organic Syntheses. 204-204. DOI: 10.1002/0471264180.Os070.23 |
0.392 |
|
| 2003 |
Wender PA, Holt DA, Sieburth SM. 2‐Alkenyl Carbinols from 2‐Halo Ketones: 2‐E‐Propenylcyclohexanol Organic Syntheses. 10-10. DOI: 10.1002/0471264180.Os064.02 |
0.319 |
|
| 2003 |
Wender PA, Eissenstat MA, Sapuppo N, Ziegler FE. Nitriles from Ketones: Cyclohexanecarbonitrile Organic Syntheses. 101-101. DOI: 10.1002/0471264180.Os058.18 |
0.702 |
|
| 2003 |
Wender PA, Baryza JL, Brenner SE, Clarke MO, Gamber GG, Horan JC, Jessop TC, Kan C, Pattabiraman K, Williams TJ. Inspirations from nature. New reactions, therapeutic leads, and drug delivery systems Pure and Applied Chemistry. 75: 143-155. |
0.772 |
|
| 2002 |
Wender PA, Gulledge AV, Jankowski OD, Seto H. Isoapoptolidin: structure and activity of the ring-expanded isomer of apoptolidin. Organic Letters. 4: 3819-22. PMID 12599467 DOI: 10.1021/Ol0266222 |
0.789 |
|
| 2002 |
Wender PA, Pedersen TM, Scanio MJ. Transition metal-catalyzed hetero-[5 + 2] cycloadditions of cyclopropyl imines and alkynes: dihydroazepines from simple, readily available starting materials. Journal of the American Chemical Society. 124: 15154-5. PMID 12487573 DOI: 10.1021/Ja0285013 |
0.811 |
|
| 2002 |
Wender PA, Williams TJ. [(arene)Rh(cod)]+ Complexes as catalysts for [5+2] cycloaddition reactions. Angewandte Chemie (International Ed. in English). 41: 4550-3. PMID 12458535 DOI: 10.1002/1521-3773(20021202)41:23<4550::Aid-Anie4550>3.0.Co;2-D |
0.449 |
|
| 2002 |
Wender PA, Baryza JL, Bennett CE, Bi FC, Brenner SE, Clarke MO, Horan JC, Kan C, Lacôte E, Lippa B, Nell PG, Turner TM. The practical synthesis of a novel and highly potent analogue of bryostatin. Journal of the American Chemical Society. 124: 13648-9. PMID 12431074 DOI: 10.1021/Ja027509+ |
0.783 |
|
| 2002 |
Wender PA, Rothbard JB, Jessop TC, Kreider EL, Wylie BL. Oligocarbamate molecular transporters: design, synthesis, and biological evaluation of a new class of transporters for drug delivery. Journal of the American Chemical Society. 124: 13382-3. PMID 12418880 DOI: 10.1021/Ja0275109 |
0.773 |
|
| 2002 |
Rothbard JB, Kreider E, VanDeusen CL, Wright L, Wylie BL, Wender PA. Arginine-rich molecular transporters for drug delivery: role of backbone spacing in cellular uptake. Journal of Medicinal Chemistry. 45: 3612-8. PMID 12166934 DOI: 10.1021/Jm0105676 |
0.777 |
|
| 2002 |
Wender PA, Hegde SG, Hubbard RD, Zhang L. Total synthesis of (-)-laulimalide. Journal of the American Chemical Society. 124: 4956-7. PMID 11982349 DOI: 10.1021/Ja0258428 |
0.412 |
|
| 2002 |
Wender PA, Gamber GG, Hubbard RD, Zhang L. Three-component cycloadditions: the first transition metal-catalyzed [5+2+1] cycloaddition reactions. Journal of the American Chemical Society. 124: 2876-7. PMID 11902870 DOI: 10.1021/Ja0176301 |
0.804 |
|
| 2002 |
Wender PA, Bi FC, Gamber GG, Gosselin F, Hubbard RD, Scanio MJC, Sun R, Williams TJ, Zhang L. Toward the ideal synthesis. New transition metal-catalyzed reactions inspired by novel medicinal leads Pure and Applied Chemistry. 74: 25-31. DOI: 10.1351/Pac200274010025 |
0.821 |
|
| 2002 |
Wender PA, Bi FC, Gamber GG, Gosselin F, Hubbard RD, Scanio MJC, Sun R, Williams TJ, Zhang L. Toward the ideal synthesis. New transition metal-catalyzed reactions inspired by novel medicinal leads Pure and Applied Chemistry. 74: 25-31. DOI: 10.1351/pac200274010025 |
0.814 |
|
| 2002 |
Lakshmipathi P, Grée D, Grée R, Wender PA, D'Angelo N. A facile C-C bond cleavage in epoxides and its use for the synthesis of oxygenated heterocycles by a ring expansion strategy Chemtracts. 15: 183-188. |
0.62 |
|
| 2001 |
Wender PA, Gamber GG, Scanio MJC. Serial [5+2]/[4+2] Cycloadditions: Facile, Preparative, Multi-Component Syntheses of Polycyclic Compounds from Simple, Readily Available Starting Materials. Angewandte Chemie (International Ed. in English). 40: 3895-3897. PMID 29712128 DOI: 10.1002/1521-3773(20011015)40:20<3895::Aid-Anie3895>3.0.Co;2-# |
0.794 |
|
| 2001 |
Chen L, Wright LR, Chen CH, Oliver SF, Wender PA, Mochly-Rosen D. Molecular transporters for peptides: delivery of a cardioprotective epsilonPKC agonist peptide into cells and intact ischemic heart using a transport system, R(7). Chemistry & Biology. 8: 1123-9. PMID 11755391 DOI: 10.1016/S1074-5521(01)00076-X |
0.743 |
|
| 2001 |
Wender PA, Gamber GG, Scanio MJ. Serial [5+2]/[4+2] Cycloadditions: Facile, Preparative, Multi-Component Syntheses of Polycyclic Compounds from Simple, Readily Available Starting Materials This research was supported by grant CHE-9800445 from the National Science Foundation. The Stanford Graduate Fellowship (M.J.C.S. and G.G.G.) is gratefully acknowledged. Angewandte Chemie (International Ed. in English). 40: 3895-3897. PMID 11668567 DOI: 10.1002/1521-3773(20011015)40:20<3895::AID-ANIE3895>3.0.CO;2-# |
0.768 |
|
| 2001 |
Wender PA, Jessop TC, Pattabiraman K, Pelkey ET, VanDeusen CL. An efficient, scalable synthesis of the molecular transporter octaarginine via a segment doubling strategy. Organic Letters. 3: 3229-32. PMID 11594801 DOI: 10.1021/Ol0161108 |
0.807 |
|
| 2001 |
Wender PA, Bi FC, Brodney MA, Gosselin F. Asymmetric synthesis of the tricyclic core of NGF-inducing cyathane diterpenes via a transition-metal-catalyzed [5 + 2] cycloaddition. Organic Letters. 3: 2105-8. PMID 11418060 DOI: 10.1021/ol0160699 |
0.571 |
|
| 2001 |
Wender PA, Barzilay CM, Dyckman AJ. The first intermolecular transition metal-catalyzed [5+2] cycloadditions with simple, unactivated, vinylcyclopropanes. Journal of the American Chemical Society. 123: 179-80. PMID 11273617 DOI: 10.1021/Ja0021159 |
0.704 |
|
| 2001 |
Glass T, Wender PA, Pattabiraman K, VanDeusen CL. Cooperative chemical sensing with bis-tritylacetylenes: Pinwheel receptors with metal ion recognition properties Chemtracts. 14: 186-189. |
0.762 |
|
| 2000 |
Irie K, Nakahara A, Ikawa Y, Tanaka M, Nakagawa Y, Nakamura Y, Ohigashi H, Wender PA. Synthesis and tumor-promoting activities of 12-Epi-phorbol-12,13-dibutyrate. Bioscience, Biotechnology, and Biochemistry. 64: 2429-36. PMID 11193412 DOI: 10.1271/Bbb.64.2429 |
0.328 |
|
| 2000 |
Wender PA, Mitchell DJ, Pattabiraman K, Pelkey ET, Steinman L, Rothbard JB. The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. Proceedings of the National Academy of Sciences of the United States of America. 97: 13003-8. PMID 11087855 DOI: 10.1073/Pnas.97.24.13003 |
0.632 |
|
| 2000 |
Wender PA, Zhang L. Asymmetric total synthesis of (+)-aphanamol I based on the transition metal catalyzed [5 + 2] cycloaddition of allenes and vinylcyclopropanes. Organic Letters. 2: 2323-6. PMID 10930274 |
0.3 |
|
| 2000 |
Wender PA, Dyckman AJ, Husfeld CO, Scanio MJ. A new and practical five-carbon component for metal-catalyzed Organic Letters. 2: 1609-11. PMID 10841491 DOI: 10.1021/Ol0058691 |
0.796 |
|
| 2000 |
Wender PA, Correa AG, Sato Y, Sun R. Transition metal-catalyzed [6+2] cycloadditions of 2-vinylcyclobutanones and alkenes: A new reaction for the synthesis of eight-membered rings [3] Journal of the American Chemical Society. 122: 7815-7816. DOI: 10.1021/Ja001483+ |
0.589 |
|
| 2000 |
Wender PA, Lippa B. Synthesis and biological evaluation of bryostatin analogues: The role of the A-ring Tetrahedron Letters. 41: 1007-1011. DOI: 10.1016/S0040-4039(99)02195-4 |
0.758 |
|
| 2000 |
Wender PA, Hinkle KW. Synthesis and biological evaluation of a new class of bryostatin analogues: The role of the C20 substituent in protein kinase C binding Tetrahedron Letters. 41: 6725-6729. DOI: 10.1016/S0040-4039(00)01100-X |
0.372 |
|
| 2000 |
Wender PA, Dyckman AJ, Husfeld CO, Scanio MJC. A New and Practical Five-Carbon Component for Metal-Catalyzed [5 + 2] Cycloadditions: Preparative Scale Syntheses of Substituted Cycloheptenones Organic Letters. 2: 1609-1611. |
0.794 |
|
| 1999 |
Wender PA, Kirschberg TA, Williams PD, Bastiaans HM, Irie K. A new class of simplified phorbol ester analogues: synthesis and binding to PKC and eta PKC-C1B (eta PKC-CRD2). Organic Letters. 1: 1009-12. PMID 10825954 DOI: 10.1021/Ol990809K |
0.378 |
|
| 1999 |
Wender PA, Hinkle KW, Koehler MF, Lippa B. The rational design of potential chemotherapeutic agents: synthesis of bryostatin analogues. Medicinal Research Reviews. 19: 388-407. PMID 10502742 DOI: 10.1002/(Sici)1098-1128(199909)19:5<388::Aid-Med6>3.0.Co;2-H |
0.777 |
|
| 1999 |
Wender PA, Lippa B, Park CM, Irie K, Nakahara A, Ohigashi H. Selective binding of bryostatin analogues to the cysteine rich domains of protein kinase C isozymes. Bioorganic & Medicinal Chemistry Letters. 9: 1687-90. PMID 10397502 DOI: 10.1016/S0960-894X(99)00263-2 |
0.721 |
|
| 1999 |
Wender PA, Koehler MFT, Wright DL, Irie K. Mapping phorbol ester binding domains of protein kinase C (PKC): The design, synthesis and biological activity of novel phorbol ester dimers Synthesis. 1401-1406. DOI: 10.1055/S-1999-3656 |
0.331 |
|
| 1999 |
Wender PA, Fuji M, Husfeld CO, Love JA. Rhodium-catalyzed [5 + 2] cycloadditions of allenes and vinylcyclopropanes: Asymmetric total synthesis of (+)-dictamnol Organic Letters. 1: 137-139. DOI: 10.1021/Ol990599B |
0.822 |
|
| 1999 |
Wender PA, Dyckman AJ, Husfeld CO, Kadereit D, Love JA, Rieck H. Transition metal-catalyzed [5+2] cycloadditions with substituted cyclopropanes: First studies of regio- and stereoselectivity [14] Journal of the American Chemical Society. 121: 10442-10443. DOI: 10.1021/Ja992580+ |
0.792 |
|
| 1999 |
Wender PA, Glorius F, Husfeld CO, Langkopf E, Love JA. Transition metal-catalyzed [5 + 2] cycloadditions of allenes and vinylcyclopropanes: First studies of endo-exo selectivity, chemoselectivity, relative stereochemistry, and chirality transfer Journal of the American Chemical Society. 121: 5348-5349. DOI: 10.1021/Ja9903072 |
0.79 |
|
| 1999 |
Wender PA, Dyckman AJ. Transition metal-catalyzed [5 + 2] cycloadditions of 2-substituted-1-vinylcyclopropanes: Catalyst control and reversal of regioselectivity Organic Letters. 1: 2089-2092. |
0.689 |
|
| 1999 |
Corey EJ, Roberts BE, Boukouvalas J, Cheng YX, Robichaud J, Magnuson SR, Sepp-Lorenzino L, Rosen N, Danishefsky SJ, Wender PA, Love JA. Organic synthesis delivers on another medicinal lead: Total syntheses of dysidiolide Chemtracts. 12: 512-521. |
0.526 |
|
| 1998 |
Wender PA, DeBrabander J, Harran PG, Jimenez JM, Koehler MF, Lippa B, Park CM, Siedenbiedel C, Pettit GR. The design, computer modeling, solution structure, and biological evaluation of synthetic analogs of bryostatin 1. Proceedings of the National Academy of Sciences of the United States of America. 95: 6624-9. PMID 9618462 DOI: 10.1073/Pnas.95.12.6624 |
0.797 |
|
| 1998 |
Wender PA, Martin-Cantalejo Y, Carpenter AJ, Chiu A, De Brabander J, Harran PG, Jimenez JM, Koehler MFT, Lippa B, Morrison JA, Müller SG, Müller SN, Park CM, Shiozaki M, Siedenbiedel C, et al. The chemistry-medicine continuum: Synthetic, computer, spectroscopic and biological studies on new chemotherapeutic leads Pure and Applied Chemistry. 70: 539-546. DOI: 10.1351/Pac199870030539 |
0.817 |
|
| 1998 |
Wender PA, Rieck H, Fuji M. The transition metal-catalyzed intermolecular [5+2] cycloaddition: The homologous Diels-Alder reaction [1] Journal of the American Chemical Society. 120: 10976-10977. DOI: 10.1021/Ja982196X |
0.35 |
|
| 1998 |
Wender PA, Husfeld CO, Langkopf E, Love JA. First studies of the transition of metal-catalyzed [5+2] cycloadditions of alkenes and vinylcyclopropanes: Scope and stereochemistry Journal of the American Chemical Society. 120: 1940-1941. DOI: 10.1021/Ja973650K |
0.787 |
|
| 1998 |
Wender PA, De Brabander J, Harran PG, Limenez JM, Koehler MFT, Lippa B, Park CM, Shiozaki M. Synthesis of the first members of a new class of biologically active bryostatin analogues [2] Journal of the American Chemical Society. 120: 4534-4535. DOI: 10.1021/Ja9727631 |
0.811 |
|
| 1998 |
Wender PA, Dore TM. A formal synthesis of crinipellin B based on the arene-alkene meta- photocycloaddition reaction Tetrahedron Letters. 39: 8589-8592. DOI: 10.1016/S0040-4039(98)01965-0 |
0.399 |
|
| 1998 |
Wender PA, De Brabander J, Harran PG, Hinkle KW, Lippa B, Pettit GR. Synthesis and biological evaluation of fully synthetic bryostatin analogues Tetrahedron Letters. 39: 8625-8628. DOI: 10.1016/S0040-4039(98)01955-8 |
0.813 |
|
| 1998 |
Wender PA, Husfeld CO, Langkopf E, Love JA, Pleuss N. The first metal-catalyzed intramolecular [5+2] cycloadditions of vinylcyclopropanes and alkenes: Scope, stereochemistry, and asymmetric catalysis Tetrahedron. 54: 7203-7220. DOI: 10.1016/S0040-4020(98)00355-X |
0.823 |
|
| 1998 |
Wender PA, Smith TE. Transition metal-catalyzed intramolecular [4+2] cycloadditions: Mechanistic and synthetic investigations Tetrahedron. 54: 1255-1275. DOI: 10.1016/S0040-4020(97)10223-X |
0.548 |
|
| 1997 |
Wender PA, Nuss JM, Smith DB, Suárez-Sobrino A, Vågberg J, Decosta D, Bordner J. Transition Metal Catalyzed Cycloadditions: An Intramolecular [4 + 4] Cycloaddition Strategy for the Efficient Synthesis of Dicyclopenta[a,d]cyclooctene 5-8-5 Ring Systems Journal of Organic Chemistry. 62: 4908-4909. DOI: 10.1021/Jo970841X |
0.697 |
|
| 1997 |
Wender PA, Jesudason CD, Nakahira H, Tamura N, Tebbe AL, Ueno Y. The First Synthesis of a Daphnane Diterpene: The Enantiocontrolled Total Synthesis of (+)-Resiniferatoxin Journal of the American Chemical Society. 119: 12976-12977. DOI: 10.1021/Ja972279Y |
0.383 |
|
| 1997 |
Wender PA, Rice KD, Schnute ME. The first formal asymmetry synthesis of phorbol Journal of the American Chemical Society. 119: 7897-7898. DOI: 10.1021/Ja9706256 |
0.372 |
|
| 1997 |
Wender PA, Badham NF, Conway SP, Floreancig PE, Glass TE, Houze JB, Krauss NE, Lee D, Marquess DG, McGrane PL, Meng W, Natchus MG, Shuker AJ, Sutton JC, Taylor RE. The pinene path to taxanes. 6. A concise stereocontrolled synthesis of taxol Journal of the American Chemical Society. 119: 2757-2758. DOI: 10.1021/Ja963539Z |
0.806 |
|
| 1997 |
Wender PA, Badham NF, Conway SP, Floreancig PE, Glass TE, Granicher C, Houze JB, Janichen J, Lee D, Marquess DG, McGrane PL, Meng W, Mucciaro TP, Muhlebach M, Natchus MG, et al. The pinene path tot taxanes. 5. Stereocontrolled synthesis of a versatile taxane precursor Journal of the American Chemical Society. 119: 2755-2756. DOI: 10.1021/Ja9635387 |
0.806 |
|
| 1997 |
Wender PA, Lee D, Lal TK, Horwitz SB, Rao S. Synthesis of novel taxol analogs and evaluation of their biological activities Bioorganic and Medicinal Chemistry Letters. 7: 1941-1944. DOI: 10.1016/S0960-894X(97)00337-5 |
0.568 |
|
| 1997 |
Wender PA, Lee D. Enantioselective synthesis of neocarzinostatin chromophore aglycon Chemtracts. 10: 653-660. |
0.412 |
|
| 1997 |
Harran PG, Wender PA. Alkynylation of C-H bonds via reaction with acetylenic triflones Chemtracts. 10: 522-526. |
0.752 |
|
| 1997 |
Wender PA, Handy ST, Wright DL. Towards the ideal synthesis Chemistry and Industry (London). X-XI. |
0.565 |
|
| 1996 |
Wender PA. Introduction: Frontiers in Organic Synthesis. Chemical Reviews. 96: 1-2. PMID 11848741 DOI: 10.1021/Cr9500803 |
0.301 |
|
| 1996 |
Wender PA, Glass TE, Krauss NE, Mühlebach M, Peschke B, Rawlins DB. The Pinene Path to Taxanes. 4. Approaches to Taxol and Taxol Analogs through Elaboration of Aromatic C-Ring Precursors. The Journal of Organic Chemistry. 61: 7662-7663. PMID 11667717 DOI: 10.1021/Jo961289Z |
0.608 |
|
| 1996 |
Wender PA, Smith TE. Transition Metal-Catalyzed Intramolecular [4 + 2] Cycloadditions: A Novel Method for the Assembly of Nitrogen Heterocycles and Its Application to Yohimban Alkaloid Synthesis The Journal of Organic Chemistry. 61: 824-825. DOI: 10.1021/Jo9519827 |
0.544 |
|
| 1996 |
Irie K, Ishii T, Ohigashi H, Wender PA, Miller BL, Takeda N. Synthesis and Characterization of New Photolabile Phorbol Esters for Affinity Labeling of Protein Kinase C The Journal of Organic Chemistry. 61: 2164-2173. DOI: 10.1021/Jo9512867 |
0.517 |
|
| 1996 |
Irie K, Isaka T, Iwata Y, Yanai Y, Nakamura Y, Koizumi F, Ohigashi H, Wender PA, Satomi Y, Nishino H. Synthesis and biological activities of new conformationally restricted analogues of (-)-indolactam-V: Elucidation of the biologically active conformation of the tumor-promoting teleocidins Journal of the American Chemical Society. 118: 10733-10743. DOI: 10.1021/Ja961727J |
0.329 |
|
| 1996 |
Irie K, Yanai Y, Ohigashi H, Wender PA, Miller BL. Synthesis and characterization of the second cysteine-rich region of mouse skin PKCGh Bioorganic & Medicinal Chemistry Letters. 6: 353-356. DOI: 10.1016/0960-894X(96)00026-1 |
0.459 |
|
| 1995 |
Wender PA, Irie K, Miller BL. Identification, activity, and structural studies of peptides incorporating the phorbol ester-binding domain of protein kinase C. Proceedings of the National Academy of Sciences of the United States of America. 92: 239-43. PMID 7816824 DOI: 10.1073/Pnas.92.1.239 |
0.498 |
|
| 1995 |
Wender PA, Glass TE. The Pinene Approach to Taxanes 2: Development of a Versatile C9, C10 Linker Synlett. 1995: 516-518. DOI: 10.1055/S-1995-5293 |
0.572 |
|
| 1995 |
Wender PA, Smith TE. Transition Metal-Catalyzed Intramolecular [4 + 2] Cycloadditions: Initial Studies on Stereochemistry and on Steroid and Vitamin D Analog Syntheses The Journal of Organic Chemistry. 60: 2962-2963. DOI: 10.1021/Jo00115A006 |
0.488 |
|
| 1995 |
Wender PA, Takahashi H, Witulski B. Transition Metal Catalyzed [5 + 2] Cycloadditions of Vinylcyclopropanes and Alkynes: A Homolog of the Diels-Alder Reaction for the Synthesis of Seven-Membered Rings Journal of the American Chemical Society. 117: 4720-4721. DOI: 10.1021/Ja00121A036 |
0.414 |
|
| 1995 |
Wender PA, Jenkins TE, Suzuki S. Transition Metal-Catalyzed Intramolecular [4 + 2] Diene-Allene Cycloadditions: A Convenient Synthesis of Angularly Substituted Ring Systems with Provision for Catalyst-Controlled Chemo- and Stereocomplementarity Journal of the American Chemical Society. 117: 1843-1844. DOI: 10.1021/Ja00111A028 |
0.385 |
|
| 1995 |
Wender PA, Wessjohann LA, Peschke B, Rawlins DB. The pinene path to taxol: Readily accessible a-ring building blocks based on novel alkyl- and alkenyllithium reagents with internal carbonyl groups Tetrahedron Letters. 36: 7181-7184. DOI: 10.1016/0040-4039(95)01491-Y |
0.552 |
|
| 1995 |
Wender PA, Floreancig PE, Glass TE, Natchus MG, Shuker AJ, Sutton JC. Toward the synthesis of taxol and its analogs: Incorporation of non-aromatic C-rings in the pinene pathway Tetrahedron Letters. 36: 4939-4942. DOI: 10.1016/0040-4039(95)00897-L |
0.751 |
|
| 1995 |
Wender PA, Beckham S, Mohler DL. The intramolecular addition of silylated alkynes to aldehydes: Methodology for the construction of cyclic enediynes and its application to dynemicin analogs Tetrahedron Letters. 36: 209-212. DOI: 10.1016/0040-4039(94)02249-B |
0.702 |
|
| 1994 |
Wender PA, Beckham S, O'Leary JG. A Second Generation Photochemically Activatable Dynemicin Analog: A Concise Synthesis and DNA Cleavage Studies Synthesis. 1994: 1278-1282. DOI: 10.1055/S-1994-25681 |
0.314 |
|
| 1994 |
Wender PA, Tebbe MJ. The synthesis and chemistry of a simplified, functional analogue of neocarzinostatin chromophore: identification of an intramolecular 1,5-hydrogen atom Tetrahedron. 50: 1419-1434. DOI: 10.1016/S0040-4020(01)80627-X |
0.383 |
|
| 1993 |
Wender PA, Zercher CK, Beckham S, Haubold EM. A photochemically triggered DNA cleaving agent: Synthesis, mechanistic and DNA cleavage studies on a new analog of the antitumor antibiotic dynemicin Journal of Organic Chemistry. 58: 5867-5869. DOI: 10.1021/Jo00074A001 |
0.665 |
|
| 1993 |
Wender PA, Irie K, Miller BL. Synthesis and binding of photoaffinity ligand candidates for protein kinase C The Journal of Organic Chemistry. 58: 4179-4181. DOI: 10.1021/Jo00068A001 |
0.512 |
|
| 1992 |
Wender PA, Mucciaro TP. A new and practical approach to the synthesis of taxol and taxol analogs: the pinene path. Journal of the American Chemical Society. 114: 5878-5879. DOI: 10.1021/Ja00040A070 |
0.347 |
|
| 1992 |
Wender PA, Rawlins DB. Toward the synthesis of the taxol C,D, ring system: Photolysis of α-methoxy ketones Tetrahedron. 48: 7033-7048. DOI: 10.1016/S0040-4020(01)91212-8 |
0.364 |
|
| 1992 |
Wender PA, Mascareñas JL. Preparation and cycloadditions of a 4-methoxy-3-oxidopyrylium ylid: a reagent for the synthesis of highly substituted seven-membered rings and tetrahydrofurans Tetrahedron Letters. 33: 2115-2118. DOI: 10.1016/0040-4039(92)88154-W |
0.356 |
|
| 1991 |
Wender PA, Kelly RC, Beckham S, Miller BL. Studies on DNA-cleaving agents: computer modeling analysis of the mechanism of activation and cleavage of dynemicin-oligonucleotide complexes. Proceedings of the National Academy of Sciences of the United States of America. 88: 8835-9. PMID 1924343 DOI: 10.1073/Pnas.88.19.8835 |
0.484 |
|
| 1991 |
Wender PA, Tebbe MJ. Nickel(0)-Catalyzed Intramolecular [4 + 4] Cycloadditions: 5. The Type II Reaction in the Synthesis of Bicyclo[5.3.1]undecadienes Synthesis. 1991: 1089-1094. DOI: 10.1055/S-1991-28397 |
0.403 |
|
| 1991 |
Wender PA, Mascarenas JL. Studies on tumor promoters. 11. A new [5+2] cycloaddition method and its application to the synthesis of BC ring precursors of phorboids The Journal of Organic Chemistry. 56: 6267-6269. DOI: 10.1021/Jo00022A009 |
0.591 |
|
| 1991 |
Wender PA, Zercher CK. Studies on DNA-cleaving agents: synthesis of a functional dynemicin analogue Journal of the American Chemical Society. 113: 2311-2313. DOI: 10.1021/Ja00006A065 |
0.708 |
|
| 1991 |
Wender PA, Tebbe MJ. Studies on DNA cleaving agents: synthesis and chemically induced cycloaromatization of a monocyclic neocarzinostatin chromophore analogue Tetrahedron Letters. 32: 4863-4866. DOI: 10.1016/S0040-4039(00)93481-6 |
0.399 |
|
| 1990 |
Wender PA, Ternansky R, deLong M, Singh S, Olivero A, Rice K. Arene-alkene cycloadditions and organic synthesis Pure and Applied Chemistry. 62: 1597-1602. DOI: 10.1351/Pac199062081597 |
0.405 |
|
| 1990 |
Wender PA, Manly CJ. Discovery of a new fragmentation reaction Journal of the American Chemical Society. 112: 8579-8581. DOI: 10.1021/Ja00179A051 |
0.355 |
|
| 1990 |
Wender PA, McKinney JA, Mukai C. General methodology for the synthesis of neocarzinostatin chromophore analogs: intramolecular chromium-mediated closures for strained ring synthesis Journal of the American Chemical Society. 112: 5369-5370. DOI: 10.1021/Ja00169A065 |
0.364 |
|
| 1990 |
Wender PA, McDonald FE. Studies on tumor promoters. 9. A second-generation synthesis of phorbol Journal of the American Chemical Society. 112: 4956-4958. DOI: 10.1021/Ja00168A050 |
0.56 |
|
| 1990 |
Wender PA, McDonald FE. Studies on tumor promoters. 10. Synthesis of the abc ring system of the tiglianes and daphnanes by a zirconium-mediated intramolecular enyne carbocyclization Tetrahedron Letters. 31: 3691-3694. DOI: 10.1016/S0040-4039(00)97446-X |
0.603 |
|
| 1990 |
Wender PA, Wisniewski Grissom J, Hoffmann U, Mah R. Hetero-atom substituted chromium allyls: Synthetic studies on neocarzinostatin chromophore analogues Tetrahedron Letters. 31: 6605-6608. DOI: 10.1016/S0040-4039(00)97126-0 |
0.358 |
|
| 1990 |
Wender PA, Singh SK. Synthetic studies on arene-olefin cycloadditions. 11. Total synthesis of (−)-retigeranic acid Tetrahedron Letters. 31: 2517-2520. DOI: 10.1016/0040-4039(90)80114-2 |
0.348 |
|
| 1990 |
WENDER PA, MCDONALD FE. ChemInform Abstract: Tumor Promoters. Part 9. A Second-Generation Synthesis of Phorbol Cheminform. 21. DOI: 10.1002/chin.199041347 |
0.515 |
|
| 1989 |
Wender PA, Jenkins TE. Nickel-catalyzed intramolecular [4 + 2] dienyne cycloadditions: an efficient new method for the synthesis of polycycles containing cyclohexa-1,4-dienes Journal of the American Chemical Society. 111: 6432-6434. DOI: 10.1021/Ja00198A071 |
0.406 |
|
| 1988 |
Wender PA, Cribbs CM, Koehler KF, Sharkey NA, Herald CL, Kamano Y, Pettit GR, Blumberg PM. Modeling of the bryostatins to the phorbol ester pharmacophore on protein kinase C. Proceedings of the National Academy of Sciences of the United States of America. 85: 7197-201. PMID 3174627 DOI: 10.1073/Pnas.85.19.7197 |
0.326 |
|
| 1988 |
Wender PA, Ihle NC, Correia CRD. Nickel-catalyzed intramolecular [4+4] cycloadditions. 4. Enantioselective total synthesis of (+)-asteriscanolide Journal of the American Chemical Society. 110: 5904-5906. DOI: 10.1021/Ja00225A055 |
0.313 |
|
| 1988 |
Wender PA, Von Geldern TW, Levine BH. Synthetic studies on arene-olefin cycloadditions. 10. A concise, stereocontrolled total synthesis of (.+-.)-laurenene Journal of the American Chemical Society. 110: 4858-4860. DOI: 10.1021/Ja00222A072 |
0.422 |
|
| 1988 |
Wender PA, Harmata M, Jeffrey D, Mukai C, Suffert J. Studies on DNA - active agents: The synthesis of the parent carbocyclic subunit of neocarzinostatin chromophore A Tetrahedron Letters. 29: 909-912. DOI: 10.1016/S0040-4039(00)82479-X |
0.711 |
|
| 1988 |
Wender PA, Brighty K. Studies on tumor promoters: V. Complementary 1,4-stereocontrol in phorboid cycloheptene synthesis via the divinylcyclopropane rearrangement Tetrahedron Letters. 29: 6741-6744. DOI: 10.1016/S0040-4039(00)82443-0 |
0.395 |
|
| 1988 |
WENDER PA, VON GELDERN TW, LEVINE BH. ChemInform Abstract: Synthetic Studies on Arene-Olefin Cycloadditions. Part 10. A Concise, Stereocontrolled Total Synthesis of (.+-.)-Laurenene. Cheminform. 19. DOI: 10.1002/chin.198846296 |
0.304 |
|
| 1987 |
Wender PA, Correia CRD. Intramolecular photoinduced diene-diene cyaloadditions: a selective method for the synthesis of complex eight-membered rings and polyquinanes Journal of the American Chemical Society. 109: 2523-2525. DOI: 10.1021/Ja00242A053 |
0.357 |
|
| 1987 |
Wender PA, Snapper ML. Intramolecular nickel catalyzed cycloadditions of bis-dienes: 3 approaches to the taxane skeleton Tetrahedron Letters. 28: 2221-2224. DOI: 10.1016/S0040-4039(00)96085-4 |
0.674 |
|
| 1987 |
Wender PA, Ihle NC. Nickel-catalyzed intramolecular [4+4] cycloadditions: 2. Allylic stereoinduction and modelling studies in the preparation of bicyclo[6.4.0]dodecadienes Tetrahedron Letters. 28: 2451-2454. DOI: 10.1016/S0040-4039(00)95438-8 |
0.363 |
|
| 1987 |
Wender PA, Cooper CB. Indole synthesis based on triazole photochemistry: Total synthesis of7-methoxymitosene Tetrahedron Letters. 28: 6125-6128. DOI: 10.1016/S0040-4039(00)61825-7 |
0.417 |
|
| 1987 |
WENDER PA, SNAPPER ML. ChemInform Abstract: Intramolecular Nickel Catalyzed Cycloadditions of Bisdienes: 3 Approaches to the Taxane Skeleton. Cheminform. 18. DOI: 10.1002/chin.198745134 |
0.598 |
|
| 1986 |
Wender PA, Koehler KF, Sharkey NA, Dell'Aquila ML, Blumberg PM. Analysis of the phorbol ester pharmacophore on protein kinase C as a guide to the rational design of new classes of analogs. Proceedings of the National Academy of Sciences of the United States of America. 83: 4214-8. PMID 3086877 DOI: 10.1073/Pnas.83.12.4214 |
0.356 |
|
| 1986 |
Wender PA, Ihle NC. Nickel-catalyzed intramolecular [4 + 4]-cycloadditions: a new method for the synthesis of polycycles containing eight-membered rings Journal of the American Chemical Society. 108: 4678-4679. DOI: 10.1021/Ja00275A085 |
0.404 |
|
| 1986 |
Wender PA, Fisher K. Seven-membered ring synthesis based on arene olefin cycloadditions: The total synthesis of (±)-Rudmollin Tetrahedron Letters. 27: 1857-1860. DOI: 10.1016/S0040-4039(00)84394-4 |
0.404 |
|
| 1986 |
Wender PA, Cooper CB. The photochemistry of 1-alkenylbenzotriazoles Tetrahedron. 42: 2985-2991. DOI: 10.1016/S0040-4020(01)90589-7 |
0.389 |
|
| 1985 |
Wender PA, Wolanin DJ. Total synthesis of quadrone and terrecyclic acid A The Journal of Organic Chemistry. 50: 4418-4420. DOI: 10.1021/Jo00222A055 |
0.313 |
|
| 1985 |
Wender PA, Holt DA. Macroexpansion methodology. 3. Eight-step synthesis of (-)-(3Z)-cembrene A Journal of the American Chemical Society. 107: 7771-7772. DOI: 10.1021/Ja00311A096 |
0.36 |
|
| 1985 |
Wender PA, Ternansky RJ, Sieburth SM. An enolate-accelerated cope rearrangement Tetrahedron Letters. 26: 4319-4322. DOI: 10.1016/S0040-4039(00)98723-9 |
0.635 |
|
| 1985 |
Wender PA, Ternansky RJ. Synthetic studies on arene-olepin cycloadditions-VII:1 a three-step total synthesis of (±)-silphinene Tetrahedron Letters. 26: 2625-2628. DOI: 10.1016/S0040-4039(00)98120-6 |
0.323 |
|
| 1983 |
Wender PA, Holt DA, Sieburth SM. Practical method for .alpha.-alkenyl ketone synthesis based on a facile reductive rearrangement of alkynyl halohydrins Journal of the American Chemical Society. 105: 3348-3350. DOI: 10.1021/Ja00348A072 |
0.625 |
|
| 1983 |
Wender P, Howbert J. Synthetic studies on areneolefin cycloadditions -VI- two syntheses of (±)-coriolin. Tetrahedron Letters. 24: 5325-5328. DOI: 10.1016/S0040-4039(00)87859-4 |
0.345 |
|
| 1983 |
Wender PA, Dreyer GB. Synthetic studies on arene-olefin cycloadditions - V. total synthesis of (±)-isoiridomyrmecin. Tetrahedron Letters. 24: 4543-4546. DOI: 10.1016/S0040-4039(00)85950-X |
0.386 |
|
| 1983 |
Wender PA, White AW. Methodology for the facile and regio-controlled synthesis of indoles Tetrahedron. 39: 3767-3776. DOI: 10.1016/S0040-4020(01)88618-X |
0.399 |
|
| 1983 |
WENDER PA, HOLT DA, SIEBURTH SM. ChemInform Abstract: PRACTICAL METHOD FOR α-ALKENYL KETONE SYNTHESIS BASED ON A FACILE REDUCTIVE REARRANGEMENT OF ALKYNYL HALOHYDRINS Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198335099 |
0.606 |
|
| 1983 |
WENDER PA, DREYER GB. ChemInform Abstract: SYNTHETIC STUDIES ON ARENE-OLEFIN CYCLOADDITIONS. 4. TOTAL SYNTHESIS OF (.+-.)-MODHEPHENE Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198304343 |
0.3 |
|
| 1982 |
Wender PA, Dreyer GB. Synthetic studies on arene-olefin cycloadditions. 4. Total synthesis of (.+-.)-modhephene Journal of the American Chemical Society. 104: 5805-5807. DOI: 10.1021/Ja00385A051 |
0.42 |
|
| 1982 |
Wender P, Howbert J. Synthetic studies on arene-olefin cycloadditions -III- total synthesis of (±)-hirsutene Tetrahedron Letters. 23: 3983-3986. DOI: 10.1016/S0040-4039(00)88675-X |
0.359 |
|
| 1982 |
Wender PA, Eck SL. The olefin metathesis/transannular ene sequence: a method for the stereocontrolled synthesis of -decalin derivatives. 3. total synthesis of (±)-warburganal Tetrahedron Letters. 23: 1871-1874. DOI: 10.1016/S0040-4039(00)87207-X |
0.3 |
|
| 1981 |
Wender PA, Erhardt JM, Letendre LJ. Reaction of allylically substituted enolates with organometallic reagents: a convenient source of enolonium ion equivalents Journal of the American Chemical Society. 103: 2114-2116. DOI: 10.1021/Ja00398A051 |
0.319 |
|
| 1981 |
Wender PA, Sieburth SM. Macroexpansion methodology: an efficient eight unit ring expansion Tetrahedron Letters. 22: 2471-2474. DOI: 10.1016/S0040-4039(01)92935-1 |
0.626 |
|
| 1981 |
Wender PA, White AW. Methodology for indole synthesis Tetrahedron Letters. 22: 1475-1478. DOI: 10.1016/S0040-4039(01)90354-5 |
0.414 |
|
| 1981 |
Wender PA, Sieburth SM, Petraitis JJ, Singh SK. Macroexpansion methodology Tetrahedron. 37: 3967-3975. DOI: 10.1016/S0040-4020(01)93271-5 |
0.646 |
|
| 1981 |
Wender PA, Dreyer GB. Synthetic studies on arene-olefin cycloadditions. ii. total synthesis of (±)-isocomene Tetrahedron. 37: 4445-4450. DOI: 10.1016/0040-4020(81)80011-7 |
0.336 |
|
| 1980 |
Wender PA, Letendre LJ. The olefin metathesis-transannular ene sequence: a method for the stereocontrolled synthesis of trans-decalin derivatives. 2. Formal eudesmane syntheses The Journal of Organic Chemistry. 45: 367-368. DOI: 10.1021/Jo01290A040 |
0.343 |
|
| 1980 |
Wender PA, Hubbs JC. Olefin metathesis-transannular ene sequence. A method for the stereocontrolled synthesis of trans-decalin derivatives. 1. Total synthesis of (.+-.)-calameon The Journal of Organic Chemistry. 45: 365-367. DOI: 10.1021/Jo01290A039 |
0.363 |
|
| 1980 |
Wender PA, Lechleiter JC. Total synthesis of (.+-.)-isabelin Journal of the American Chemical Society. 102: 6340-6341. DOI: 10.1021/Ja00540A029 |
0.372 |
|
| 1980 |
Wender PA, Schaus JM, White AW. General methodology for cis-hydroisoquinoline synthesis: synthesis of reserpine Journal of the American Chemical Society. 102: 6157-6159. DOI: 10.1021/Ja00539A038 |
0.34 |
|
| 1979 |
Wender PA, Eissenstat MA, Filosa MP. A general methodology for pseudoguaiane synthesis: total synthesis of (.+-.)-damsinic acid and (.+-.)-confertin Journal of the American Chemical Society. 101: 2196-2198. DOI: 10.1021/Ja00502A042 |
0.354 |
|
| 1979 |
Wender PA, Schaus JM, Torney DC. A general method for -hydroisoquinoline synthesis Tetrahedron Letters. 20: 2485-2488. DOI: 10.1016/S0040-4039(01)86327-9 |
0.324 |
|
| 1978 |
Wender PA, Lechleiter JC. A photochemically mediated [4C + 2C] annelation. Synthesis of (.+-.)-10-epijunenol Journal of the American Chemical Society. 100: 4321-4322. DOI: 10.1021/Ja00481A062 |
0.328 |
|
| 1977 |
Ziegler FE, Wender PA. Methyldialkylcyanodiazenecarboxylates as intermediates for transforming aliphatic ketones into nitriles The Journal of Organic Chemistry. 42: 2001-2003. DOI: 10.1021/Jo00431A036 |
0.686 |
|
| 1977 |
Ziegler FE, Reid GR, Studt WL, Wender PA. Stereochemistry of dialkylcuprate additions to cyclopropyl acrylic esters. An application to the synthesis of (.+-.)-eremophilone The Journal of Organic Chemistry. 42: 1991-2001. DOI: 10.1021/Jo00431A035 |
0.737 |
|
| 1974 |
Ziegler FE, Wender PA. The stereospecific generation of the cis-vicinal methyls in eremophilane and valencane sesquiterpenes: The total synthesis of (±) eremophilone and (±) 7-epieremophilone. Tetrahedron Letters. 15: 449-452. DOI: 10.1016/S0040-4039(01)82239-5 |
0.654 |
|
| 1971 |
Ziegler FE, Wender PA. Base-induced decomposition of methyl dialkylcyanodiazenecarboxylates. Transformation of ketones into nitriles, .alpha.-carbomethoxynitriles, and .alpha.-methylnitriles Journal of the American Chemical Society. 93: 4318-4319. DOI: 10.1021/Ja00746A052 |
0.668 |
|
| 1971 |
ZIEGLER FE, WENDER PA. ChemInform Abstract: BASENINDUZIERTE ZERS. VON DIALKYLCYANDIAZENCARBONSAEUREMETHYLESTERN, UMWANDLUNG VON KETONEN IN NITRILE, ALPHA-METHOXYCARBONYL- UND ALPHA-METHYL-NITRILE Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/Chin.197145280 |
0.662 |
|
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