Anthony Wynshaw-Boris - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Neuroscience Biology

153 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ngo J, Hashimoto M, Hamada H, Wynshaw-Boris A. Deletion of the Dishevelled family of genes disrupts anterior-posterior axis specification and selectively prevents mesoderm differentiation. Developmental Biology. PMID 32579954 DOI: 10.1016/J.Ydbio.2020.05.010  0.414
2020 Moon HM, Hippenmeyer S, Luo L, Wynshaw-Boris A. LIS1 determines cleavage plane positioning by regulating actomyosin-mediated cell membrane contractility. Elife. 9. PMID 32159512 DOI: 10.7554/Elife.51512  0.399
2019 Fang Z, Weng C, Li H, Tao R, Mai W, Liu X, Lu L, Lai S, Duan Q, Alvarez C, Arvan P, Wynshaw-Boris A, Li Y, Pei Y, Jin F, et al. Single-Cell Heterogeneity Analysis and CRISPR Screen Identify Key β-Cell-Specific Disease Genes. Cell Reports. 26: 3132-3144.e7. PMID 30865899 DOI: 10.1016/J.Celrep.2019.02.043  0.324
2018 Zhang M, Ngo J, Pirozzi F, Sun YP, Wynshaw-Boris A. Highly efficient methods to obtain homogeneous dorsal neural progenitor cells from human and mouse embryonic stem cells and induced pluripotent stem cells. Stem Cell Research & Therapy. 9: 67. PMID 29544541 DOI: 10.1186/S13287-018-0812-6  0.323
2017 Adegbola A, Bury LA, Fu C, Zhang M, Wynshaw-Boris A. Concise Review: Induced Pluripotent Stem Cell Models for Neuropsychiatric Diseases. Stem Cells Translational Medicine. PMID 29027744 DOI: 10.1002/Sctm.17-0150  0.312
2017 Bershteyn M, Nowakowski TJ, Pollen AA, Di Lullo E, Nene A, Wynshaw-Boris A, Kriegstein AR. Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia. Cell Stem Cell. PMID 28111201 DOI: 10.1016/J.Stem.2016.12.007  0.367
2016 Belinson H, Savage AK, Fadrosh D, Kuo YM, Lin D, Valladares R, Nusse Y, Wynshaw-Boris A, Lynch SV, Locksley RM, Klein OD. Dual epithelial and immune cell function of Dvl1 regulates gut microbiota composition and intestinal homeostasis. Jci Insight. 1. PMID 27525310 DOI: 10.1172/Jci.Insight.85395  0.351
2016 Marchetto MC, Belinson H, Tian Y, Freitas BC, Fu C, Vadodaria KC, Beltrao-Braga PC, Trujillo CA, Mendes AP, Padmanabhan K, Nunez Y, Ou J, Ghosh H, Wright R, Brennand KJ, ... ... Wynshaw-Boris A, et al. Altered proliferation and networks in neural cells derived from idiopathic autistic individuals. Molecular Psychiatry. PMID 27378147 DOI: 10.1038/Mp.2016.95  0.345
2016 Saito A, Taniguchi Y, Kim SH, Selvakumar B, Perez G, Ballinger MD, Zhu X, Sabra J, Jallow M, Yan P, Ito K, Rajendran S, Hirotsune S, Wynshaw-Boris A, Snyder SH, et al. Developmental Alcohol Exposure Impairs Activity-Dependent S-Nitrosylation of NDEL1 for Neuronal Maturation. Cerebral Cortex (New York, N.Y. : 1991). PMID 27371763 DOI: 10.1093/Cercor/Bhw201  0.336
2016 Belinson H, Nakatani J, Babineau BA, Birnbaum RY, Ellegood J, Bershteyn M, McEvilly RJ, Long JM, Willert K, Klein OD, Ahituv N, Lerch JP, Rosenfeld MG, Wynshaw-Boris A. Prenatal β-catenin/Brn2/Tbr2 transcriptional cascade regulates adult social and stereotypic behaviors. Molecular Psychiatry. PMID 26830142 DOI: 10.1038/Mp.2015.207  0.332
2015 Sinha T, Lin L, Li D, Davis J, Evans S, Wynshaw-Boris A, Wang J. Mapping the dynamic expression of Wnt11 and the lineage contribution of Wnt11-expressing cells during early mouse development. Developmental Biology. 398: 177-92. PMID 25448697 DOI: 10.1016/J.Ydbio.2014.11.005  0.758
2014 Toyo-oka K, Wachi T, Hunt RF, Baraban SC, Taya S, Ramshaw H, Kaibuchi K, Schwarz QP, Lopez AF, Wynshaw-Boris A. 14-3-3ε and ζ regulate neurogenesis and differentiation of neuronal progenitor cells in the developing brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12168-81. PMID 25186760 DOI: 10.1523/Jneurosci.2513-13.2014  0.403
2014 Ohata S, Nakatani J, Herranz-Pérez V, Cheng J, Belinson H, Inubushi T, Snider WD, García-Verdugo JM, Wynshaw-Boris A, Alvarez-Buylla A. Loss of Dishevelleds disrupts planar polarity in ependymal motile cilia and results in hydrocephalus. Neuron. 83: 558-71. PMID 25043421 DOI: 10.1016/J.Neuron.2014.06.022  0.385
2014 Ye M, Parente F, Li X, Perryman MB, Zelante L, Wynshaw-Boris A, Chen J, Grossfeld P. Gene-targeted deletion of OPCML and Neurotrimin in mice does not yield congenital heart defects. American Journal of Medical Genetics. Part A. 164: 966-74. PMID 24616287 DOI: 10.1002/Ajmg.A.36441  0.341
2014 Bershteyn M, Hayashi Y, Desachy G, Hsiao EC, Sami S, Tsang KM, Weiss LA, Kriegstein AR, Yamanaka S, Wynshaw-Boris A. Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells. Nature. 507: 99-103. PMID 24413397 DOI: 10.1038/Nature12923  0.324
2014 Moon HM, Youn YH, Pemble H, Yingling J, Wittmann T, Wynshaw-Boris A. LIS1 controls mitosis and mitotic spindle organization via the LIS1-NDEL1-dynein complex. Human Molecular Genetics. 23: 449-66. PMID 24030547 DOI: 10.1093/Hmg/Ddt436  0.714
2013 Moon HM, Wynshaw-Boris A. Cytoskeleton in action: lissencephaly, a neuronal migration disorder. Wiley Interdisciplinary Reviews. Developmental Biology. 2: 229-45. PMID 23495356 DOI: 10.1002/Wdev.67  0.361
2013 Toba S, Tamura Y, Kumamoto K, Yamada M, Takao K, Hattori S, Miyakawa T, Kataoka Y, Azuma M, Hayasaka K, Amamoto M, Tominaga K, Wynshaw-Boris A, Wanibuchi H, Oka Y, et al. Post-natal treatment by a blood-brain-barrier permeable calpain inhibitor, SNJ1945 rescued defective function in lissencephaly. Scientific Reports. 3: 1224. PMID 23390575 DOI: 10.1038/Srep01224  0.317
2013 Huang X, McGann JC, Liu BY, Hannoush RN, Lill JR, Pham V, Newton K, Kakunda M, Liu J, Yu C, Hymowitz SG, Hongo JA, Wynshaw-Boris A, Polakis P, Harland RM, et al. Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling. Science (New York, N.Y.). 339: 1441-5. PMID 23371553 DOI: 10.1126/Science.1232253  0.352
2013 Sebe JY, Bershteyn M, Hirotsune S, Wynshaw-Boris A, Baraban SC. ALLN rescues an in vitro excitatory synaptic transmission deficit in Lis1 mutant mice. Journal of Neurophysiology. 109: 429-36. PMID 23100132 DOI: 10.1152/Jn.00431.2012  0.349
2012 Wynshaw-Boris A. Dishevelled: in vivo roles of a multifunctional gene family during development. Current Topics in Developmental Biology. 101: 213-35. PMID 23140631 DOI: 10.1016/B978-0-12-394592-1.00007-7  0.423
2012 Kosaka Y, Cieslik KA, Li L, Lezin G, Maguire CT, Saijoh Y, Toyo-oka K, Gambello MJ, Vatta M, Wynshaw-Boris A, Baldini A, Yost HJ, Brunelli L. 14-3-3ε plays a role in cardiac ventricular compaction by regulating the cardiomyocyte cell cycle. Molecular and Cellular Biology. 32: 5089-102. PMID 23071090 DOI: 10.1128/Mcb.00829-12  0.351
2012 Takitoh T, Kumamoto K, Wang CC, Sato M, Toba S, Wynshaw-Boris A, Hirotsune S. Activation of Aurora-A is essential for neuronal migration via modulation of microtubule organization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11050-66. PMID 22875938 DOI: 10.1523/Jneurosci.5664-11.2012  0.325
2012 Sinha T, Wang B, Evans S, Wynshaw-Boris A, Wang J. Disheveled mediated planar cell polarity signaling is required in the second heart field lineage for outflow tract morphogenesis. Developmental Biology. 370: 135-44. PMID 22841628 DOI: 10.1016/J.Ydbio.2012.07.023  0.776
2012 Wang J, Sinha T, Wynshaw-Boris A. Wnt signaling in mammalian development: lessons from mouse genetics. Cold Spring Harbor Perspectives in Biology. 4. PMID 22550229 DOI: 10.1101/Cshperspect.A007963  0.757
2012 Chow ML, Pramparo T, Winn ME, Barnes CC, Li HR, Weiss L, Fan JB, Murray S, April C, Belinson H, Fu XD, Wynshaw-Boris A, Schork NJ, Courchesne E. Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. Plos Genetics. 8: e1002592. PMID 22457638 DOI: 10.1371/Journal.Pgen.1002592  0.352
2012 Cheah PS, Ramshaw HS, Thomas PQ, Toyo-Oka K, Xu X, Martin S, Coyle P, Guthridge MA, Stomski F, van den Buuse M, Wynshaw-Boris A, Lopez AF, Schwarz QP. Neurodevelopmental and neuropsychiatric behaviour defects arise from 14-3-3ζ deficiency. Molecular Psychiatry. 17: 451-66. PMID 22124272 DOI: 10.1038/Mp.2011.158  0.322
2011 Pramparo T, Libiger O, Jain S, Li H, Youn YH, Hirotsune S, Schork NJ, Wynshaw-Boris A. Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defects. Plos Genetics. 7: e1001331. PMID 21423666 DOI: 10.1371/Journal.Pgen.1001331  0.45
2010 Hippenmeyer S, Youn YH, Moon HM, Miyamichi K, Zong H, Wynshaw-Boris A, Luo L. Genetic mosaic dissection of Lis1 and Ndel1 in neuronal migration. Neuron. 68: 695-709. PMID 21092859 DOI: 10.1016/J.Neuron.2010.09.027  0.385
2010 Wynshaw-Boris A, Pramparo T, Youn YH, Hirotsune S. Lissencephaly: mechanistic insights from animal models and potential therapeutic strategies. Seminars in Cell & Developmental Biology. 21: 823-30. PMID 20688183 DOI: 10.1016/J.Semcdb.2010.07.008  0.362
2010 Yamada M, Hirotsune S, Wynshaw-Boris A. A novel strategy for therapeutic intervention for the genetic disease: preventing proteolytic cleavage using small chemical compound. The International Journal of Biochemistry & Cell Biology. 42: 1401-7. PMID 20541031 DOI: 10.1016/J.Biocel.2010.05.017  0.379
2010 Pramparo T, Youn YH, Yingling J, Hirotsune S, Wynshaw-Boris A. Novel embryonic neuronal migration and proliferation defects in Dcx mutant mice are exacerbated by Lis1 reduction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3002-12. PMID 20181597 DOI: 10.1523/Jneurosci.4851-09.2010  0.719
2010 Yamada M, Hirotsune S, Wynshaw-Boris A. The essential role of LIS1, NDEL1 and Aurora-A in polarity formation and microtubule organization during neurogensis. Cell Adhesion & Migration. 4: 180-4. PMID 20168084 DOI: 10.4161/Cam.4.2.10715  0.413
2010 Hashimoto M, Shinohara K, Wang J, Ikeuchi S, Yoshiba S, Meno C, Nonaka S, Takada S, Hatta K, Wynshaw-Boris A, Hamada H. Planar polarization of node cells determines the rotational axis of node cilia. Nature Cell Biology. 12: 170-6. PMID 20098415 DOI: 10.1038/Ncb2020  0.449
2009 Youn YH, Pramparo T, Hirotsune S, Wynshaw-Boris A. Distinct dose-dependent cortical neuronal migration and neurite extension defects in Lis1 and Ndel1 mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 15520-30. PMID 20007476 DOI: 10.1523/Jneurosci.4630-09.2009  0.41
2009 Yamada M, Yoshida Y, Mori D, Takitoh T, Kengaku M, Umeshima H, Takao K, Miyakawa T, Sato M, Sorimachi H, Wynshaw-Boris A, Hirotsune S. Inhibition of calpain increases LIS1 expression and partially rescues in vivo phenotypes in a mouse model of lissencephaly. Nature Medicine. 15: 1202-7. PMID 19734909 DOI: 10.1038/Nm.2023  0.393
2009 Mori D, Yamada M, Mimori-Kiyosue Y, Shirai Y, Suzuki A, Ohno S, Saya H, Wynshaw-Boris A, Hirotsune S. An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics. Nature Cell Biology. 11: 1057-68. PMID 19668197 DOI: 10.1038/Ncb1919  0.324
2009 Davies K, Wynshaw-Boris A. Human genetics: conceptual and practical advances in the post-genome era Current Opinion in Genetics and Development. 19: 193-195. PMID 19481439 DOI: 10.1016/J.Gde.2009.05.002  0.34
2009 Wynshaw-Boris A. Elongator bridges tubulin acetylation and neuronal migration. Cell. 136: 393-4. PMID 19203572 DOI: 10.1016/J.Cell.2009.01.024  0.318
2009 Hashimoto M, Ikeuchi S, Wang J, Shinohara K, Nonaka S, Wynshaw-Boris A, Hamada H. 16-P018 Cell polarity in the node for basal body positioning and nodal flow Mechanisms of Development. 126. DOI: 10.1016/J.Mod.2009.06.709  0.41
2008 Etheridge SL, Ray S, Li S, Hamblet NS, Lijam N, Tsang M, Greer J, Kardos N, Wang J, Sussman DJ, Chen P, Wynshaw-Boris A. Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development. Plos Genetics. 4: e1000259. PMID 19008950 DOI: 10.1371/Journal.Pgen.1000259  0.561
2008 Ikeda M, Hikita T, Taya S, Uraguchi-Asaki J, Toyo-oka K, Wynshaw-Boris A, Ujike H, Inada T, Takao K, Miyakawa T, Ozaki N, Kaibuchi K, Iwata N. Identification of YWHAE, a gene encoding 14-3-3epsilon, as a possible susceptibility gene for schizophrenia. Human Molecular Genetics. 17: 3212-22. PMID 18658164 DOI: 10.1093/Hmg/Ddn217  0.302
2008 Pawlisz AS, Mutch C, Wynshaw-Boris A, Chenn A, Walsh CA, Feng Y. Lis1-Nde1-dependent neuronal fate control determines cerebral cortical size and lamination. Human Molecular Genetics. 17: 2441-55. PMID 18469343 DOI: 10.1093/Hmg/Ddn144  0.392
2008 Toyo-oka K, Mori D, Yano Y, Shiota M, Iwao H, Goto H, Inagaki M, Hiraiwa N, Muramatsu M, Wynshaw-Boris A, Yoshiki A, Hirotsune S. Protein phosphatase 4 catalytic subunit regulates Cdk1 activity and microtubule organization via NDEL1 dephosphorylation. The Journal of Cell Biology. 180: 1133-47. PMID 18347064 DOI: 10.1083/Jcb.200705148  0.339
2008 Yingling J, Youn YH, Darling D, Toyo-Oka K, Pramparo T, Hirotsune S, Wynshaw-Boris A. Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division. Cell. 132: 474-86. PMID 18267077 DOI: 10.1016/J.Cell.2008.01.026  0.698
2008 Zeng X, Huang H, Tamai K, Zhang X, Harada Y, Yokota C, Almeida K, Wang J, Doble B, Woodgett J, Wynshaw-Boris A, Hsieh JC, He X. Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Development (Cambridge, England). 135: 367-75. PMID 18077588 DOI: 10.1242/Dev.013540  0.463
2008 Hebbar S, Guillotte AM, Mesngon MT, Zhou Q, Wynshaw-Boris A, Smith DS. Genetic enhancement of the Lis1+/- phenotype by a heterozygous mutation in the adenomatous polyposis coli gene. Developmental Neuroscience. 30: 157-70. PMID 18075263 DOI: 10.1159/000109860  0.418
2007 Wynshaw-Boris A. Lissencephaly and LIS1: insights into the molecular mechanisms of neuronal migration and development. Clinical Genetics. 72: 296-304. PMID 17850624 DOI: 10.1111/J.1399-0004.2007.00888.X  0.397
2007 Zhou W, Lin L, Majumdar A, Li X, Zhang X, Liu W, Etheridge L, Shi Y, Martin J, Van de Ven W, Kaartinen V, Wynshaw-Boris A, McMahon AP, Rosenfeld MG, Evans SM. Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2. Nature Genetics. 39: 1225-34. PMID 17767158 DOI: 10.1038/Ng2112  0.347
2007 Hedlund M, Tangvoranuntakul P, Takematsu H, Long JM, Housley GD, Kozutsumi Y, Suzuki A, Wynshaw-Boris A, Ryan AF, Gallo RL, Varki N, Varki A. N-glycolylneuraminic acid deficiency in mice: implications for human biology and evolution. Molecular and Cellular Biology. 27: 4340-6. PMID 17420276 DOI: 10.1128/Mcb.00379-07  0.371
2007 Wynshaw-Boris A. Cell biology: lost in mitotic translation. Nature. 446: 274-5. PMID 17361171 DOI: 10.1038/446274A  0.349
2007 Zhang G, Assadi AH, McNeil RS, Beffert U, Wynshaw-Boris A, Herz J, Clark GD, D'Arcangelo G. The Pafah1b complex interacts with the reelin receptor VLDLR. Plos One. 2: e252. PMID 17330141 DOI: 10.1371/Journal.Pone.0000252  0.305
2007 Van De Schans VAM, Van Den Borne SWM, Strzelecka AE, Janssen BJA, Van Der Velden JLJ, Langen RCJ, Wynshaw-Boris A, Smits JFM, Blankesteijn WM. Interruption of Wnt signaling attenuates the onset of pressure overload-induced cardiac hypertrophy Hypertension. 49: 473-480. PMID 17210832 DOI: 10.1161/01.Hyp.0000255946.55091.24  0.358
2007 Mori D, Yano Y, Toyo-oka K, Yoshida N, Yamada M, Muramatsu M, Zhang D, Saya H, Toyoshima YY, Kinoshita K, Wynshaw-Boris A, Hirotsune S. NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment. Molecular and Cellular Biology. 27: 352-67. PMID 17060449 DOI: 10.1128/Mcb.00878-06  0.339
2006 Wynshaw-Boris A. Inborn errors of development: disruption of pathways critical for normal development. Pediatric Clinics of North America. 53: 855-71, viii. PMID 17027614 DOI: 10.1016/J.Pcl.2006.08.008  0.381
2006 Long JM, LaPorte P, Merscher S, Funke B, Saint-Jore B, Puech A, Kucherlapati R, Morrow BE, Skoultchi AI, Wynshaw-Boris A. Behavior of mice with mutations in the conserved region deleted in velocardiofacial/DiGeorge syndrome. Neurogenetics. 7: 247-57. PMID 16900388 DOI: 10.1007/S10048-006-0054-0  0.394
2006 Erker L, Schubert R, Elchuri S, Huang TT, Tarin D, Mueller K, Zielen S, Epstein CJ, Wynshaw-Boris A. Effect of the reduction of superoxide dismutase 1 and 2 or treatment with alpha-tocopherol on tumorigenesis in Atm-deficient mice. Free Radical Biology & Medicine. 41: 590-600. PMID 16863992 DOI: 10.1016/J.Freeradbiomed.2006.04.032  0.735
2006 Toyo-oka K, Bowen TJ, Hirotsune S, Li Z, Jain S, Ota S, Escoubet-Lozach L, Lozach LE, Garcia-Bassets I, Bassett IG, Lozach J, Rosenfeld MG, Glass CK, Eisenman R, Ren B, ... ... Wynshaw-Boris A, et al. Mnt-deficient mammary glands exhibit impaired involution and tumors with characteristics of myc overexpression. Cancer Research. 66: 5565-73. PMID 16740691 DOI: 10.1158/0008-5472.Can-05-2683  0.671
2006 Greer JM, Wynshaw-Boris A. Pten and the brain: sizing up social interaction. Neuron. 50: 343-5. PMID 16675386 DOI: 10.1016/J.Neuron.2006.04.021  0.319
2006 Nasrallah IM, McManus MF, Pancoast MM, Wynshaw-Boris A, Golden JA. Analysis of non-radial interneuron migration dynamics and its disruption in Lis1+/- mice. The Journal of Comparative Neurology. 496: 847-58. PMID 16628622 DOI: 10.1002/Cne.20966  0.402
2006 Wang J, Hamblet NS, Mark S, Dickinson ME, Brinkman BC, Segil N, Fraser SE, Chen P, Wallingford JB, Wynshaw-Boris A. Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation. Development (Cambridge, England). 133: 1767-78. PMID 16571627 DOI: 10.1242/Dev.02347  0.531
2006 Dezfouli S, Bakke A, Huang J, Wynshaw-Boris A, Hurlin PJ. Inflammatory disease and lymphomagenesis caused by deletion of the Myc antagonist Mnt in T cells. Molecular and Cellular Biology. 26: 2080-92. PMID 16507988 DOI: 10.1128/Mcb.26.6.2080-2092.2006  0.315
2006 Kholmanskikh SS, Koeller HB, Wynshaw-Boris A, Gomez T, Letourneau PC, Ross ME. Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility. Nature Neuroscience. 9: 50-7. PMID 16369480 DOI: 10.1038/Nn1619  0.348
2005 Bowen TJ, Yakushiji H, Montagna C, Jain S, Ried T, Wynshaw-Boris A. Atm heterozygosity cooperates with loss of Brca1 to increase the severity of mammary gland cancer and reduce ductal branching. Cancer Research. 65: 8736-46. PMID 16204043 DOI: 10.1158/0008-5472.Can-05-1598  0.67
2005 Toyo-Oka K, Sasaki S, Yano Y, Mori D, Kobayashi T, Toyoshima YY, Tokuoka SM, Ishii S, Shimizu T, Muramatsu M, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S. Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration. Human Molecular Genetics. 14: 3113-28. PMID 16203747 DOI: 10.1093/Hmg/Ddi339  0.378
2005 Darling DL, Yingling J, Wynshaw-Boris A. Role of 14-3-3 proteins in eukaryotic signaling and development. Current Topics in Developmental Biology. 68: 281-315. PMID 16125003 DOI: 10.1016/S0070-2153(05)68010-6  0.659
2005 Wang J, Mark S, Zhang X, Qian D, Yoo SJ, Radde-Gallwitz K, Zhang Y, Lin X, Collazo A, Wynshaw-Boris A, Chen P. Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway. Nature Genetics. 37: 980-5. PMID 16116426 DOI: 10.1038/Ng1622  0.479
2005 Sasaki S, Mori D, Toyo-oka K, Chen A, Garrett-Beal L, Muramatsu M, Miyagawa S, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S. Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality. Molecular and Cellular Biology. 25: 7812-27. PMID 16107726 DOI: 10.1128/Mcb.25.17.7812-7827.2005  0.45
2005 Winrow CJ, Pankratz DG, Vibat CR, Bowen TJ, Callahan MA, Warren AJ, Hilbush BS, Wynshaw-Boris A, Hasel KW, Weaver Z, Lockhart DJ, Barlow C. Aberrant recombination involving the granzyme locus occurs in Atm-/- T-cell lymphomas. Human Molecular Genetics. 14: 2671-84. PMID 16087685 DOI: 10.1093/Hmg/Ddi301  0.678
2005 Erker L, Schubert R, Yakushiji H, Barlow C, Larson D, Mitchell JB, Wynshaw-Boris A. Cancer chemoprevention by the antioxidant tempol acts partially via the p53 tumor suppressor. Human Molecular Genetics. 14: 1699-708. PMID 15888486 DOI: 10.1093/Hmg/Ddi181  0.742
2005 Walker W, Zhou ZQ, Ota S, Wynshaw-Boris A, Hurlin PJ. Mnt-Max to Myc-Max complex switching regulates cell cycle entry. The Journal of Cell Biology. 169: 405-13. PMID 15866886 DOI: 10.1083/Jcb.200411013  0.322
2005 Rosso SB, Sussman D, Wynshaw-Boris A, Salinas PC. Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development. Nature Neuroscience. 8: 34-42. PMID 15608632 DOI: 10.1038/Nn1374  0.365
2005 Zhou X, Long JM, Geyer MA, Masliah E, Kelsoe JR, Wynshaw-Boris A, Chien KR. Reduced expression of the Sp4 gene in mice causes deficits in sensorimotor gating and memory associated with hippocampal vacuolization. Molecular Psychiatry. 10: 393-406. PMID 15558077 DOI: 10.1038/Sj.Mp.4001621  0.342
2004 Lumsden JM, McCarty T, Petiniot LK, Shen R, Barlow C, Wynn TA, Morse HC, Gearhart PJ, Wynshaw-Boris A, Max EE, Hodes RJ. Immunoglobulin class switch recombination is impaired in Atm-deficient mice. The Journal of Experimental Medicine. 200: 1111-21. PMID 15504820 DOI: 10.1084/Jem.20041074  0.35
2004 Wang J, Wynshaw-Boris A. The canonical Wnt pathway in early mammalian embryogenesis and stem cell maintenance/differentiation. Current Opinion in Genetics & Development. 14: 533-9. PMID 15380245 DOI: 10.1016/J.Gde.2004.07.013  0.537
2004 McManus MF, Nasrallah IM, Pancoast MM, Wynshaw-Boris A, Golden JA. Lis1 is necessary for normal non-radial migration of inhibitory interneurons. The American Journal of Pathology. 165: 775-84. PMID 15331402 DOI: 10.1016/S0002-9440(10)63340-8  0.381
2004 Schubert R, Erker L, Barlow C, Yakushiji H, Larson D, Russo A, Mitchell JB, Wynshaw-Boris A. Cancer chemoprevention by the antioxidant tempol in Atm-deficient mice. Human Molecular Genetics. 13: 1793-802. PMID 15213104 DOI: 10.1093/Hmg/Ddh189  0.739
2004 Tanaka T, Serneo FF, Higgins C, Gambello MJ, Wynshaw-Boris A, Gleeson JG. Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migration. The Journal of Cell Biology. 165: 709-21. PMID 15173193 DOI: 10.1083/Jcb.200309025  0.336
2004 Angata K, Long JM, Bukalo O, Lee W, Dityatev A, Wynshaw-Boris A, Schachner M, Fukuda M, Marth JD. Sialyltransferase ST8Sia-II assembles a subset of polysialic acid that directs hippocampal axonal targeting and promotes fear behavior. The Journal of Biological Chemistry. 279: 32603-13. PMID 15140899 DOI: 10.1074/Jbc.M403429200  0.334
2004 Toyo-oka K, Hirotsune S, Gambello MJ, Zhou ZQ, Olson L, Rosenfeld MG, Eisenman R, Hurlin P, Wynshaw-Boris A. Loss of the Max-interacting protein Mnt in mice results in decreased viability, defective embryonic growth and craniofacial defects: relevance to Miller-Dieker syndrome. Human Molecular Genetics. 13: 1057-67. PMID 15028671 DOI: 10.1093/Hmg/Ddh116  0.442
2004 Hurlin PJ, Zhou ZQ, Toyo-Oka K, Ota S, Walker WL, Hirotsune S, Wynshaw-Boris A. Evidence of mnt-myc antagonism revealed by mnt gene deletion. Cell Cycle (Georgetown, Tex.). 3: 97-9. PMID 14712062 DOI: 10.4161/Cc.3.2.638  0.325
2003 Assadi AH, Zhang G, Beffert U, McNeil RS, Renfro AL, Niu S, Quattrocchi CC, Antalffy BA, Sheldon M, Armstrong DD, Wynshaw-Boris A, Herz J, D'Arcangelo G, Clark GD. Interaction of reelin signaling and Lis1 in brain development. Nature Genetics. 35: 270-6. PMID 14578885 DOI: 10.1038/Ng1257  0.407
2003 Furuno-Fukushi I, Masumura K, Furuse T, Noda Y, Takahagi M, Saito T, Hoki Y, Suzuki H, Wynshaw-Boris A, Nohmi T, Tatsumi K. Effect of Atm disruption on spontaneously arising and radiation-induced deletion mutations in mouse liver. Radiation Research. 160: 549-58. PMID 14565827 DOI: 10.1667/Rr3073  0.312
2003 Kholmanskikh SS, Dobrin JS, Wynshaw-Boris A, Letourneau PC, Ross ME. Disregulated RhoGTPases and actin cytoskeleton contribute to the migration defect in Lis1-deficient neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8673-81. PMID 14507966 DOI: 10.1523/Jneurosci.23-25-08673.2003  0.373
2003 Hurlin PJ, Zhou ZQ, Toyo-oka K, Ota S, Walker WL, Hirotsune S, Wynshaw-Boris A. Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis. The Embo Journal. 22: 4584-96. PMID 12970171 DOI: 10.1093/Emboj/Cdg442  0.421
2003 Cahana A, Jin XL, Reiner O, Wynshaw-Boris A, O'Neill C. A study of the nature of embryonic lethality in LIS1-/- mice. Molecular Reproduction and Development. 66: 134-42. PMID 12950100 DOI: 10.1002/Mrd.10339  0.37
2003 Tokuoka SM, Ishii S, Kawamura N, Satoh M, Shimada A, Sasaki S, Hirotsune S, Wynshaw-Boris A, Shimizu T. Involvement of platelet-activating factor and LIS1 in neuronal migration. The European Journal of Neuroscience. 18: 563-70. PMID 12911752 DOI: 10.1046/J.1460-9568.2003.02778.X  0.348
2003 Yingling J, Toyo-Oka K, Wynshaw-Boris A. Miller-Dieker syndrome: analysis of a human contiguous gene syndrome in the mouse. American Journal of Human Genetics. 73: 475-88. PMID 12905154 DOI: 10.1086/378096  0.683
2003 Schriml LM, Hill DP, Blake JA, Bono H, Wynshaw-Boris A, Pavan WJ, Ring BZ, Beisel K, Setou M, Okazaki Y. Human disease genes and their cloned mouse orthologs: exploration of the FANTOM2 cDNA sequence data set. Genome Research. 13: 1496-500. PMID 12819148 DOI: 10.1101/Gr.979503  0.301
2003 Toyo-oka K, Shionoya A, Gambello MJ, Cardoso C, Leventer R, Ward HL, Ayala R, Tsai LH, Dobyns W, Ledbetter D, Hirotsune S, Wynshaw-Boris A. 14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. Nature Genetics. 34: 274-85. PMID 12796778 DOI: 10.1038/Ng1169  0.407
2003 Hirotsune S, Yoshida N, Chen A, Garrett L, Sugiyama F, Takahashi S, Yagami K, Wynshaw-Boris A, Yoshiki A. An expressed pseudogene regulates the messenger-RNA stability of its homologous coding gene. Nature. 423: 91-6. PMID 12721631 DOI: 10.1038/Nature01535  0.325
2003 Baek SH, Kioussi C, Briata P, Wang D, Nguyen HD, Ohgi KA, Glass CK, Wynshaw-Boris A, Rose DW, Rosenfeld MG. Regulated subset of G1 growth-control genes in response to derepression by the Wnt pathway. Proceedings of the National Academy of Sciences of the United States of America. 100: 3245-50. PMID 12629224 DOI: 10.1073/Pnas.0330217100  0.344
2003 Gambello MJ, Darling DL, Yingling J, Tanaka T, Gleeson JG, Wynshaw-Boris A. Multiple dose-dependent effects of Lis1 on cerebral cortical development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1719-29. PMID 12629176 DOI: 10.1523/Jneurosci.23-05-01719.2003  0.723
2003 Cardoso C, Leventer RJ, Ward HL, Toyo-oka K, Chung J, Gross A, Martin CL, Allanson J, Pilz DT, Olney AH, Mutchinick OM, Hirotsune S, Wynshaw-Boris A, Dobyns WB, Ledbetter DH. Refinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3 American Journal of Human Genetics. 72: 918-930. PMID 12621583 DOI: 10.1086/374320  0.321
2002 Kioussi C, Briata P, Baek SH, Rose DW, Hamblet NS, Herman T, Ohgi KA, Lin C, Gleiberman A, Wang J, Brault V, Ruiz-Lozano P, Nguyen HD, Kemler R, Glass CK, ... Wynshaw-Boris A, et al. Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development. Cell. 111: 673-85. PMID 12464179 DOI: 10.1016/S0092-8674(02)01084-X  0.502
2002 Hamblet NS, Lijam N, Ruiz-Lozano P, Wang J, Yang Y, Luo Z, Mei L, Chien KR, Sussman DJ, Wynshaw-Boris A. Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure. Development (Cambridge, England). 129: 5827-38. PMID 12421720 DOI: 10.1242/Dev.00164  0.533
2002 Corbo JC, Deuel TA, Long JM, LaPorte P, Tsai E, Wynshaw-Boris A, Walsh CA. Doublecortin is required in mice for lamination of the hippocampus but not the neocortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7548-57. PMID 12196578 DOI: 10.1523/Jneurosci.22-17-07548.2002  0.388
2002 Luo ZG, Wang Q, Zhou JZ, Wang J, Luo Z, Liu M, He X, Wynshaw-Boris A, Xiong WC, Lu B, Mei L. Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1. Neuron. 35: 489-505. PMID 12165471 DOI: 10.1016/S0896-6273(02)00783-3  0.435
2002 Gupta A, Tsai LH, Wynshaw-Boris A. Life is a journey: a genetic look at neocortical development. Nature Reviews. Genetics. 3: 342-55. PMID 11988760 DOI: 10.1038/Nrg799  0.32
2002 Roberts C, Sutherland HF, Farmer H, Kimber W, Halford S, Carey A, Brickman JM, Wynshaw-Boris A, Scambler PJ. Targeted mutagenesis of the Hira gene results in gastrulation defects and patterning abnormalities of mesoendodermal derivatives prior to early embryonic lethality. Molecular and Cellular Biology. 22: 2318-28. PMID 11884616 DOI: 10.1128/Mcb.22.7.2318-2328.2002  0.371
2001 Wang Y, Tan J, Sutton-Smith M, Ditto D, Panico M, Campbell RM, Varki NM, Long JM, Jaeken J, Levinson SR, Wynshaw-Boris A, Morris HR, Le D, Dell A, Schachter H, et al. Modeling human congenital disorder of glycosylation type IIa in the mouse: conservation of asparagine-linked glycan-dependent functions in mammalian physiology and insights into disease pathogenesis. Glycobiology. 11: 1051-70. PMID 11805078 DOI: 10.1093/Glycob/11.12.1051  0.374
2001 Lechleider RJ, Ryan JL, Garrett L, Eng C, Deng Cx, Wynshaw-Boris A, Roberts AB. Targeted mutagenesis of Smad1 reveals an essential role in chorioallantoic fusion Developmental Biology. 240: 157-167. PMID 11784053 DOI: 10.1006/Dbio.2001.0469  0.396
2001 Wynshaw-Boris A, Gambello MJ. LIS1 and dynein motor function in neuronal migration and development Genes & Development. 15: 639-651. PMID 11274050 DOI: 10.1101/Gad.886801  0.395
2001 Resor L, Bowen TJ, Wynshaw-Boris A. Unraveling human cancer in the mouse: recent refinements to modeling and analysis. Human Molecular Genetics. 10: 669-75. PMID 11257098 DOI: 10.1093/Hmg/10.7.669  0.662
2001 Merscher S, Funke B, Epstein JA, Heyer J, Puech A, Lu MM, Xavier RJ, Demay MB, Russell RG, Factor S, Tokooya K, Jore BS, Lopez M, Pandita RK, Lia M, ... ... Wynshaw-Boris A, et al. TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome. Cell. 104: 619-29. PMID 11239417 DOI: 10.1016/S0092-8674(01)00247-1  0.37
2001 Ménisser-de Murcia J, Mark M, Wendling O, Wynshaw-Boris A, de Murcia G. Early embryonic lethality in PARP-1 Atm double-mutant mice suggests a functional synergy in cell proliferation during development. Molecular and Cellular Biology. 21: 1828-32. PMID 11238919 DOI: 10.1128/Mcb.21.5.1828-1832.2001  0.36
2001 Karabinis ME, Larson D, Barlow C, Wynshaw-Boris A, Moser AR. Heterozygosity for a mutation in Brca1 or Atm does not increase susceptibility to ENU-induced mammary tumors in ApcMin/+ mice Carcinogenesis. 22: 343-346. PMID 11181458 DOI: 10.1093/Carcin/22.2.343  0.342
2000 Sasaki S, Shionoya A, Ishida M, Gambello MJ, Yingling J, Wynshaw-Boris A, Hirotsune S. A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system Neuron. 28: 681-696. PMID 11163259 DOI: 10.1016/S0896-6273(00)00146-X  0.696
2000 Kaneshige M, Kaneshige K, Zhu X, Dace A, Garrett L, Carter TA, Kazlauskaite R, Pankratz DG, Wynshaw-Boris A, Refetoff S, Weintraub B, Willingham MC, Barlow C, Cheng S. Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone. Proceedings of the National Academy of Sciences of the United States of America. 97: 13209-14. PMID 11069286 DOI: 10.1073/Pnas.230285997  0.369
2000 Smith DS, Niethammer M, Ayala R, Zhou Y, Gambello MJ, Wynshaw-Boris A, Tsai LH. Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1. Nature Cell Biology. 2: 767-75. PMID 11056530 DOI: 10.1038/35041000  0.351
2000 Rucker EB, Dierisseau P, Wagner KU, Garrett L, Wynshaw-Boris A, Flaws JA, Hennighausen L. Bcl-x and Bax regulate mouse primordial germ cell survival and apoptosis during embryogenesis Molecular Endocrinology. 14: 1038-1052. PMID 10894153 DOI: 10.1210/Mend.14.7.0465  0.342
2000 Petiniot LK, Weaver Z, Barlow C, Shen R, Eckhaus M, Steinberg SM, Ried T, Wynshaw-Boris A, Hodes RJ. Recombinase-activating gene (RAG) 2-mediated V(D)J recombination is not essential for tumorigenesis in Atm-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 97: 6664-9. PMID 10841564 DOI: 10.1073/Pnas.97.12.6664  0.367
2000 Barlow C, Ribaut-Barassin C, Zwingman TA, Pope AJ, Brown KD, Owens JW, Larson D, Harrington EA, Haeberle AM, Mariani J, Eckhaus M, Herrup K, Bailly Y, Wynshaw-Boris A. ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation. Proceedings of the National Academy of Sciences of the United States of America. 97: 871-6. PMID 10639172 DOI: 10.1073/Pnas.97.2.871  0.422
2000 Fleck MW, Hirotsune S, Gambello MJ, Phillips-Tansey E, Suares G, Mervis RF, Wynshaw-Boris A, McBain CJ. Hippocampal Abnormalities and Enhanced Excitability in a Murine Model of Human Lissencephaly The Journal of Neuroscience. 20: 2439-2450. DOI: 10.1523/Jneurosci.20-07-02439.2000  0.342
2000 Liyanage M, Weaver Z, Barlow C, Coleman A, Pankratz DG, Anderson S, Wynshaw-Boris A, Ried T. Abnormal rearrangement within the α/δ T-cell receptor locus in lymphomas from Atm-deficient mice Blood. 96: 1940-1946. DOI: 10.1182/Blood.V96.5.1940.H8001940_1940_1946  0.335
1999 Kimber WL, Hsieh P, Hirotsune S, Yuva-Paylor L, Sutherland HF, Chen A, Ruiz-Lozano P, Hoogstraten-Miller SL, Chien KR, Paylor R, Scambler PJ, Wynshaw-Boris A. Deletion of 150 kb in the minimal DiGeorge/velocardiofacial syndrome critical region in mouse. Human Molecular Genetics. 8: 2229-37. PMID 10545603 DOI: 10.1093/Hmg/8.12.2229  0.356
1999 Paylor R, Hirotsune S, Gambello MJ, Yuva-Paylor L, Crawley JN, Wynshaw-Boris A. Impaired learning and motor behavior in heterozygous Pafah1b1 (Lis1) mutant mice. Learning & Memory (Cold Spring Harbor, N.Y.). 6: 521-37. PMID 10541472 DOI: 10.1101/Lm.6.5.521  0.381
1999 Barlow C, Dennery PA, Shigenaga MK, Smith MA, Morrow JD, Roberts LJ, Wynshaw-Boris A, Levine RL. Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs. Proceedings of the National Academy of Sciences of the United States of America. 96: 9915-9. PMID 10449794 DOI: 10.1073/Pnas.96.17.9915  0.32
1999 Gambello MJ, Hirotsune S, Wynshaw-Boris A. Murine modelling of classical lissencephaly Neurogenetics. 2: 77-86. PMID 10369882 DOI: 10.1007/S100480050056  0.331
1999 Xu X, Wagner KU, Larson D, Weaver Z, Li C, Ried T, Hennighausen L, Wynshaw-Boris A, Deng CX. Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation. Nature Genetics. 22: 37-43. PMID 10319859 DOI: 10.1038/8743  0.379
1999 Bi L, Okabe I, Bernard DJ, Wynshaw-Boris A, Nussbaum RL. Proliferative Defect and Embryonic Lethality in Mice Homozygous for a Deletion in the p110α Subunit of Phosphoinositide 3-Kinase Journal of Biological Chemistry. 274: 10963-10968. PMID 10196176 DOI: 10.1074/Jbc.274.16.10963  0.362
1999 Liao MJ, Yin C, Barlow C, Wynshaw-Boris A, van Dyke T. Atm is dispensable for p53 apoptosis and tumor suppression triggered by cell cycle dysfunction. Molecular and Cellular Biology. 19: 3095-102. PMID 10082576 DOI: 10.1128/Mcb.19.4.3095  0.338
1999 Dantzer F, Murcia JM, Barlow C, Wynshaw-Boris A, Murcia Gd. Poly(ADP-ribose) polymerase activity is not affected in ataxia telangiectasia cells and knockout mice Carcinogenesis. 20: 177-180. PMID 9934867 DOI: 10.1093/Carcin/20.1.177  0.349
1999 Brown KD, Barlow C, Wynshaw-Boris A. Multiple ATM-dependent pathways: An explanation for pleiotropy American Journal of Human Genetics. 64: 46-50. PMID 9915942 DOI: 10.1086/302223  0.333
1999 Wynshaw-Boris A, Garrett L, Chen A, Barlow C. Chapter 3.1.2 Generation of transgenic mice by pronuclear DNA injection Techniques in the Behavioral and Neural Sciences. 13: 272-281. DOI: 10.1016/S0921-0709(99)80024-8  0.367
1999 Wynshaw-Boris A, Garrett L, Chen A, Barlow C. Chapter 3.1.1 Embryonic stem cells and gene targeting Techniques in the Behavioral and Neural Sciences. 13: 259-271. DOI: 10.1016/S0921-0709(99)80023-6  0.361
1998 Yamanaka R, Lekstrom-Himes J, Barlow C, Wynshaw-Boris A, Xanthopoulos KG. CCAAT/enhancer binding proteins are critical components of the transcriptional regulation of hematopoiesis (Review). International Journal of Molecular Medicine. 1: 213-221. PMID 9852222 DOI: 10.3892/Ijmm.1.1.213  0.304
1998 Ding J, Yang L, Yan YT, Chen A, Desai N, Wynshaw-Boris A, Shen MM. Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo. Nature. 395: 702-7. PMID 9790191 DOI: 10.1038/27215  0.337
1998 Hirotsune S, Fleck MW, Gambello MJ, Bix GJ, Chen A, Clark GD, Ledbetter DH, McBain CJ, Wynshaw-Boris A. Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality. Nature Genetics. 19: 333-9. PMID 9697693 DOI: 10.1038/1221  0.397
1998 Jänne PA, Suchy SF, Bernard D, MacDonald M, Crawley J, Grinberg A, Wynshaw-Boris A, Westphal H, Nussbaum RL. Functional overlap between murine Inpp5b and Ocrl1 may explain why deficiency of the murine ortholog for OCRL1 does not cause Lowe syndrome in mice. The Journal of Clinical Investigation. 101: 2042-53. PMID 9593760 DOI: 10.1172/Jci2414  0.378
1997 Barlow C, Liyanage M, Moens PB, Deng CX, Ried T, Wynshaw-Boris A. Partial rescue of the prophase I defects of Atm-deficient mice by p53 and p21 null alleles Nature Genetics. 17: 462-466. PMID 9398851 DOI: 10.1038/Ng1297-462  0.381
1997 Barlow C, Brown KD, Deng CX, Tagle DA, Wynshaw-Boris A. Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways Nature Genetics. 17: 453-456. PMID 9398849 DOI: 10.1038/Ng1297-453  0.362
1997 Yamanaka R, Barlow C, Lekstrom-Himes J, Castilla LH, Liu PP, Eckhaus M, Decker T, Wynshaw-Boris A, Xanthopoulos KG. Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 13187-13192. PMID 9371821 DOI: 10.1073/Pnas.94.24.13187  0.371
1997 Wagner KU, Wall RJ, St-Onge L, Gruss P, Wynshaw-Boris A, Garrett L, Li M, Furth PA, Hennighausen L. Cre-mediated gene deletion in the mammary gland. Nucleic Acids Research. 25: 4323-30. PMID 9336464 DOI: 10.1093/Nar/25.21.4323  0.391
1997 Lijam N, Paylor R, McDonald MP, Crawley JN, Deng CX, Herrup K, Stevens KE, Maccaferri G, McBain CJ, Sussman DJ, Wynshaw-Boris A. Social interaction and sensorimotor gating abnormalities in mice lacking Dvl1. Cell. 90: 895-905. PMID 9298901 DOI: 10.1016/S0092-8674(00)80354-2  0.352
1997 Crawley JN, Belknap JK, Collins A, Crabbe JC, Frankel W, Henderson N, Hitzemann RJ, Maxson SC, Miner LL, Silva AJ, Wehner JM, Wynshaw-Boris A, Paylor R. Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies. Psychopharmacology. 132: 107-24. PMID 9266608 DOI: 10.1007/S002130050327  0.315
1997 Wynshaw-Boris A, Ryan G, Deng CX, Chan DC, Jackson-Grusby L, Larson D, Dunmore JH, Leder P. The role of a single formin isoform in the limb and renal phenotypes of limb deformity. Molecular Medicine (Cambridge, Mass.). 3: 372-84. PMID 9234242 DOI: 10.1007/Bf03401684  0.359
1997 Hirotsune S, Pack SD, Chong SS, Robbins CM, Pavan WJ, Ledbetter DH, Wynshaw-Boris A. Genomic organization of the murine Miller-Dieker/lissencephaly region: conservation of linkage with the human region. Genome Research. 7: 625-34. PMID 9199935 DOI: 10.1101/Gr.7.6.625  0.346
1997 Barlow C, Schroeder M, Lekstrom-Himes J, Kylefjord H, Deng CX, Wynshaw-Boris A, Spiegelman BM, Xanthopoulos KG. Targeted expression of Cre recombinase to adipose tissue of transgenic mice directs adipose-specific excision of loxP-flanked gene segments. Nucleic Acids Research. 25: 2543-5. PMID 9171115 DOI: 10.1093/Nar/25.12.2543  0.371
1997 Baskaran R, Wood LD, Whitaker LL, Canman CE, Morgan SE, Xu Y, Barlow C, Baltimore D, Wynshaw-Boris A, Kastan MB, Wang JY. Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation. Nature. 387: 516-9. PMID 9168116 DOI: 10.1038/387516A0  0.324
1997 Taylor C, Wadey R, O'Donnell H, Roberts C, Mattei MG, Kimber WL, Wynshaw-Boris A, Scambler PJ. Cloning and mapping of murine Dgcr2 and its homology to the Sez-12 seizure-related protein Mammalian Genome. 8: 371-375. PMID 9107688 DOI: 10.1007/S003359900445  0.334
1997 Liu X, Robinson GW, Wagner KU, Garrett L, Wynshaw-Boris A, Hennighausen L. Stat5a is mandatory for adult mammary gland development and lactogenesis. Genes & Development. 11: 179-86. PMID 9009201 DOI: 10.1101/Gad.11.2.179  0.402
1997 Wang Q, Stacy T, Miller JD, Lewis AF, Gu TL, Huang X, Bushweller JH, Bories JC, Alt FW, Ryan G, Liu PP, Wynshaw-Boris A, Binder M, Marín-Padilla M, Sharpe AH, et al. The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo. Cell. 87: 697-708. PMID 8929538 DOI: 10.1016/S0092-8674(00)81389-6  0.327
1997 Feldman GM, Rosenthal LA, Liu X, Hayes MP, Wynshaw-Boris A, Leonard WJ, Hennighausen L, Finbloom DS. STAT5A-Deficient Mice Demonstrate a Defect in Granulocyte-Macrophage Colony-Stimulating Factor–Induced Proliferation and Gene Expression Blood. 90: 1768-1776. DOI: 10.1182/Blood.V90.5.1768  0.401
1996 Castilla LH, Wijmenga C, Wang Q, Stacy T, Speck NA, Eckhaus M, Marín-Padilla M, Collins FS, Wynshaw-Boris A, Liu PP. Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11. Cell. 87: 687-96. PMID 8929537 DOI: 10.1016/S0092-8674(00)81388-4  0.414
1996 Tsang M, Lijam N, Yang Y, Beier DR, Wynshaw-Boris A, Sussman DJ. Isolation and characterization of mouse dishevelled-3. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 207: 253-62. PMID 8922524 DOI: 10.1002/(Sici)1097-0177(199611)207:3<253::Aid-Aja2>3.0.Co;2-G  0.374
1996 Liyanage M, Coleman A, du Manoir S, Veldman T, McCormack S, Dickson RB, Barlow C, Wynshaw-Boris A, Janz S, Wienberg J, Ferguson-Smith MA, Schröck E, Ried T. Multicolour spectral karyotyping of mouse chromosomes. Nature Genetics. 14: 312-5. PMID 8896561 DOI: 10.1038/Ng1196-312  0.305
1996 Barlow C, Hirotsune S, Paylor R, Liyanage M, Eckhaus M, Collins F, Shiloh Y, Crawley JN, Ried T, Tagle D, Wynshaw-Boris A. Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell. 86: 159-71. PMID 8689683 DOI: 10.1016/S0092-8674(00)80086-0  0.393
1996 Pecker I, Avraham KB, Gilbert DJ, Savitsky K, Rotman G, Harnik R, Fukao T, Schröck E, Hirotsune S, Tagle DA, Collins FS, Wynshaw-Boris A, Ried T, Copeland NG, Jenkins NA, et al. Identification and chromosomal localization of Atm, the mouse homolog of the ataxia-telangiectasia gene. Genomics. 35: 39-45. PMID 8661102 DOI: 10.1006/Geno.1996.0320  0.325
1996 Schröck E, Badger P, Larson D, Erdos M, Wynshaw-Boris A, Ried T, Brody L. The murine homolog of the human breast and ovarian cancer susceptibility gene Brca1 maps to mouse chromosome 11D. Human Genetics. 97: 256-9. PMID 8566965 DOI: 10.1007/Bf02265277  0.326
1995 Marquis ST, Rajan JV, Wynshaw-Boris A, Xu J, Yin GY, Abel KJ, Weber BL, Chodosh LA. The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues Nature Genetics. 11: 17-26. PMID 7550308 DOI: 10.1038/Ng0995-17  0.32
1994 Oettgen HC, Martin TR, Wynshaw-Boris A, Deng C, Drazen JM, Leder P. Active anaphylaxis in IgE-deficient mice. Nature. 370: 367-70. PMID 8047141 DOI: 10.1038/370367A0  0.375
1994 Deng CX, Wynshaw-Boris A, Shen MM, Daugherty C, Ornitz DM, Leder P. Murine FGFR-1 is required for early postimplantation growth and axial organization. Genes & Development. 8: 3045-57. PMID 8001823 DOI: 10.1101/Gad.8.24.3045  0.372
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