| Year |
Citation |
Score |
| 2024 |
Gonzalez ME, Brophy B, Eido A, Leonetti AE, Djomehri SI, Augimeri G, Carruthers NJ, Cavalcante RG, Giordano F, Andò S, Nesvizhskii AI, Fearon ER, Kleer CG. CCN6 suppresses metaplastic breast carcinoma by antagonizing WNT/β-catenin signaling to inhibit EZH2-driven EMT. Cancer Research. PMID 39024552 DOI: 10.1158/0008-5472.CAN-23-4054 |
0.325 |
|
| 2022 |
Sun D, Wang W, Guo F, Pitter MR, Du W, Wei S, Grove S, Vatan L, Chen Y, Kryczek I, Fearon ER, Fang JY, Zou W. DOT1L affects colorectal carcinogenesis via altering T cell subsets and oncogenic pathway. Oncoimmunology. 11: 2052640. PMID 35309733 DOI: 10.1080/2162402X.2022.2052640 |
0.362 |
|
| 2019 |
Fearon ER. Cancer: Context Is Key for E-cadherin in Invasion and Metastasis. Current Biology : Cb. 29: R1140-R1142. PMID 31689402 DOI: 10.1016/j.cub.2019.09.054 |
0.317 |
|
| 2019 |
Wu R, Stolfi C, Zhai Y, Fearon ER, Cho KR. Abstract AP16: MODELING ENDOMETRIOID AND HIGH GRADE SEROUS CARCINOMAS IN THE MOUSE USING CRISPR/CAS9-MEDIATED SOMATIC GENE EDITING IN FALLOPIAN TUBE EPITHELIUM Clinical Cancer Research. 25. DOI: 10.1158/1557-3265.Ovcasymp18-Ap16 |
0.391 |
|
| 2018 |
Fearon ER. MOLECULAR FEATURES AND MOUSE MODELS OF COLORECTAL CANCER. Transactions of the American Clinical and Climatological Association. 129: 56-62. PMID 30166699 |
0.305 |
|
| 2018 |
Zhai Y, Schulman S, Khandwala N, Fearon ER, Cho KR. Abstract B76: Oncogenic Kras and Pik3ca can cooperate with inactivation of various tumor suppressor genes to generate high-grade serous carcinomas in the mouse oviduct Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Ovca17-B76 |
0.405 |
|
| 2018 |
Sakamoto N, Feng Y, Hattori T, Shimoda M, Ishikawa A, Honma R, Hinoi T, Egi H, Ohdan H, Okada Y, Fearon E, Yasui W. Abstract 574: BRAFV600E mutation and loss of CDX2 synergize in serrated colorectal tumorigenesis Cancer Research. 78: 574-574. DOI: 10.1158/1538-7445.Am2018-574 |
0.426 |
|
| 2017 |
Ocadiz-Ruiz R, Photenhauer AL, Hayes MM, Ding L, Fearon ER, Merchant JL. ZBP-89 function in colonic stem cells and during butyrate-induced senescence. Oncotarget. 8: 94330-94344. PMID 29212231 DOI: 10.18632/oncotarget.21698 |
0.333 |
|
| 2017 |
Dosch J, Ziemke E, Wan S, Luker K, Welling T, Hardiman K, Fearon E, Thomas S, Flynn M, Rios-Doria J, Hollingsworth R, Herbst R, Hurt E, Sebolt-Leopold J. Targeting ADAM17 inhibits human colorectal adenocarcinoma progression and tumor-initiating cell frequency. Oncotarget. 8: 65090-65099. PMID 29029414 DOI: 10.18632/Oncotarget.17780 |
0.376 |
|
| 2017 |
Zhai Y, Wu R, Kuick R, Sessine MS, Schulman S, Green M, Fearon ER, Cho KR. High-grade serous carcinomas arise in the mouse oviduct via defects linked to the human disease. The Journal of Pathology. PMID 28608929 DOI: 10.1002/Path.4927 |
0.355 |
|
| 2017 |
Cao P, Aoki Y, Badri L, Walker NM, Manning CM, Lagstein A, Fearon ER, Lama VN. Autocrine lysophosphatidic acid signaling activates β-catenin and promotes lung allograft fibrosis. The Journal of Clinical Investigation. PMID 28240604 DOI: 10.1172/Jci88896 |
0.36 |
|
| 2017 |
Taniguchi K, Moroishi T, de Jong PR, Krawczyk M, Grebbin BM, Luo H, Xu RH, Golob-Schwarzl N, Schweiger C, Wang K, Di Caro G, Feng Y, Fearon ER, Raz E, Kenner L, et al. YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28130546 DOI: 10.1073/Pnas.1620290114 |
0.39 |
|
| 2017 |
Sakamoto N, Feng Y, Stolfi C, Kurosu Y, Green M, Lin J, Green M, Sentani K, Yasui W, McMahon M, Hardiman KM, Spence JR, Horita N, Greenson JK, Kuick R, ... ... Fearon ER, et al. BRAF(V600E) cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis. Elife. 6. PMID 28072391 DOI: 10.7554/Elife.20331 |
0.418 |
|
| 2017 |
Zhai Y, Fearon ER, Cho KR. Abstract TMEM-018: IN VITRO MODELS OF HGSC BASED ON MURINE OVIDUCTAL EPITHELIAL ORGANOIDS Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Ovcasymp16-Tmem-018 |
0.386 |
|
| 2017 |
Hardiman KM, Ulintz PJ, Greenson JK, Wu R, Fearon ER. Abstract PR07: Complex sub-clonal populations in colorectal cancer lymph node metastasis Cancer Research. 77. DOI: 10.1158/1538-7445.Crc16-Pr07 |
0.343 |
|
| 2016 |
Wu R, Zhai Y, Kuick R, Karnezis AN, Garcia P, Naseem A, Hu TC, Fearon ER, Cho KR. Impact of oviductal versus ovarian epithelial cell of origin on ovarian endometrioid carcinoma phenotype in the mouse. The Journal of Pathology. PMID 27538791 DOI: 10.1002/Path.4783 |
0.384 |
|
| 2016 |
Pedersen EA, Menon R, Bailey KM, Thomas DG, Van Noord RA, Tran J, Wang H, Qu PP, Hoering A, Fearon ER, Chugh R, Lawlor ER. Activation of Wnt/beta-catenin in Ewing sarcoma cells antagonizes EWS/ETS function and promotes phenotypic transition to more metastatic cell states. Cancer Research. PMID 27364557 DOI: 10.1158/0008-5472.CAN-15-3422 |
0.398 |
|
| 2016 |
Fearon ER, Huang EH. CDX2: Linking Cell and Patient Fates in Colon Cancer. Cell Stem Cell. 18: 168-9. PMID 26849302 DOI: 10.1016/J.Stem.2016.01.011 |
0.325 |
|
| 2016 |
Stoffel EM, Fearon ER. Germline Sequence Variants and Ovarian Cancer: Known-Knowns and Known-Unknowns. Jama Oncology. 2: 491-2. PMID 26720286 DOI: 10.1001/Jamaoncol.2015.5622 |
0.334 |
|
| 2016 |
Sakamoto N, Feng Y, Stolfi C, Kurosu Y, Green M, Lin J, Green ME, Sentani K, Yasui W, McMahon M, Hardiman KM, Spence JR, Horita N, Greenson JK, Kuick R, ... ... Fearon ER, et al. Author response: BRAFV600E cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis Elife. DOI: 10.7554/Elife.20331.033 |
0.317 |
|
| 2016 |
Pedersen EA, Menon R, Thomas DG, Bailey KM, Noord RAV, Chugh R, Fearon ER, Lawlor ER. Abstract A21: The metastasis-regulator Tenascin C is activated by Wnt/beta-catenin in Ewing sarcoma Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-A21 |
0.506 |
|
| 2016 |
Feng Y, Sakamoto N, Green M, Greenn M, Cho KR, Fearon ER. Abstract 672: Differential effects of p53 mutations on cancer invasion and metastasis in a mouse model of colon cancer Cancer Research. 76: 672-672. DOI: 10.1158/1538-7445.Am2016-672 |
0.42 |
|
| 2016 |
Wu R, Zhai Y, Kuick R, Garcia P, Naseem A, Fearon ER, Cho kR. Abstract 2684: Modeling a prototypical type I ovarian carcinoma in the mouse based on oviductal versus ovarian epithelial transformation: which is superior Cancer Research. 76: 2684-2684. DOI: 10.1158/1538-7445.Am2016-2684 |
0.392 |
|
| 2015 |
Hardiman KM, Ulintz PJ, Kuick RD, Hovelson DH, Gates CM, Bhasi A, Rodrigues Grant A, Liu J, Cani AK, Greenson JK, Tomlins SA, Fearon ER. Intra-tumor genetic heterogeneity in rectal cancer. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 26568296 DOI: 10.1038/Labinvest.2015.131 |
0.366 |
|
| 2015 |
Feng Y, Sakamoto N, Wu R, Liu JY, Wiese A, Green ME, Green M, Akyol A, Roy BC, Zhai Y, Cho KR, Fearon ER. Tissue-Specific Effects of Reduced β-catenin Expression on Adenomatous Polyposis Coli Mutation-Instigated Tumorigenesis in Mouse Colon and Ovarian Epithelium. Plos Genetics. 11: e1005638. PMID 26528816 DOI: 10.1371/Journal.Pgen.1005638 |
0.487 |
|
| 2015 |
Zhang H, Ramakrishnan SK, Triner D, Centofanti B, Maitra D, Győrffy B, Sebolt-Leopold JS, Dame MK, Varani J, Brenner DE, Fearon ER, Omary MB, Shah YM. Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1. Science Signaling. 8: ra98. PMID 26443705 DOI: 10.1126/Scisignal.Aac5418 |
0.424 |
|
| 2015 |
Zhai Y, Kuick R, Tipton C, Wu R, Sessine M, Wang Z, Baker SJ, Fearon ER, Cho KR. Arid1a inactivation in an Apc- and Pten-defective mouse ovarian cancer model enhances epithelial differentiation and prolongs survival. The Journal of Pathology. PMID 26279473 DOI: 10.1002/Path.4599 |
0.39 |
|
| 2015 |
Mazzoni SM, Petty EM, Stoffel EM, Fearon ER. An AXIN2 Mutant Allele Associated With Predisposition to Colorectal Neoplasia Has Context-Dependent Effects on AXIN2 Protein Function. Neoplasia (New York, N.Y.). 17: 463-72. PMID 26025668 DOI: 10.1016/j.neo.2015.04.006 |
0.359 |
|
| 2015 |
Fearon ER, Carethers JM. Molecular subtyping of colorectal cancer: time to explore both intertumoral and intratumoral heterogeneity to evaluate patient outcome. Gastroenterology. 148: 10-3. PMID 25451650 DOI: 10.1053/J.Gastro.2014.11.024 |
0.414 |
|
| 2015 |
Zhai Y, Wu R, Hu TC, Fearon ER, Cho KR. Abstract AS06: Development and characterization of an oviduct-specific model of high-grade serous carcinoma Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Ovcasymp14-As06 |
0.39 |
|
| 2015 |
Potu H, Peterson LF, Kandarpa M, Fearon E, Talpaz M, Donato NJ. Abstract 3621: Deubiquitination of AXIN1 by USP9X promotes apoptosis in melanoma in response to BRAF or MEK inhibition Cancer Research. 75: 3621-3621. DOI: 10.1158/1538-7445.Am2015-3621 |
0.399 |
|
| 2015 |
Pedersen EA, Menon R, Thomas D, Fearon E, Lawlor E. Abstract 3270: Distinct and heterogeneous response of Ewing sarcoma cells to canonical Wnt signaling Cancer Research. 75: 3270-3270. DOI: 10.1158/1538-7445.Am2015-3270 |
0.415 |
|
| 2014 |
Mazzoni SM, Fearon ER. AXIN1 and AXIN2 variants in gastrointestinal cancers. Cancer Letters. 355: 1-8. PMID 25236910 DOI: 10.1016/J.Canlet.2014.09.018 |
0.441 |
|
| 2014 |
Adler AS, McCleland ML, Yee S, Yaylaoglu M, Hussain S, Cosino E, Quinones G, Modrusan Z, Seshagiri S, Torres E, Chopra VS, Haley B, Zhang Z, Blackwood EM, Singh M, ... ... Fearon ER, et al. An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth. Genes & Development. 28: 1068-84. PMID 24788092 DOI: 10.1101/Gad.237206.113 |
0.427 |
|
| 2014 |
Fearon ER, Wicha MS. KRAS and cancer stem cells in APC-mutant colorectal cancer. Journal of the National Cancer Institute. 106: djt444. PMID 24491303 DOI: 10.1093/Jnci/Djt444 |
0.385 |
|
| 2014 |
Manna SK, Tanaka N, Krausz KW, Haznadar M, Xue X, Matsubara T, Bowman ED, Fearon ER, Harris CC, Shah YM, Gonzalez FJ. Biomarkers of coordinate metabolic reprogramming in colorectal tumors in mice and humans. Gastroenterology. 146: 1313-24. PMID 24440673 DOI: 10.1053/J.Gastro.2014.01.017 |
0.349 |
|
| 2013 |
Zeller J, Turbiak AJ, Powelson IA, Lee S, Sun D, Showalter HD, Fearon ER. Investigation of 3-aryl-pyrimido[5,4-e][1,2,4]triazine-5,7-diones as small molecule antagonists of β-catenin/TCF transcription. Bioorganic & Medicinal Chemistry Letters. 23: 5814-20. PMID 24060489 DOI: 10.1016/J.Bmcl.2013.08.111 |
0.405 |
|
| 2013 |
Wu R, Baker SJ, Hu TC, Norman KM, Fearon ER, Cho KR. Type I to type II ovarian carcinoma progression: mutant Trp53 or Pik3ca confers a more aggressive tumor phenotype in a mouse model of ovarian cancer. The American Journal of Pathology. 182: 1391-9. PMID 23499052 DOI: 10.1016/J.Ajpath.2012.12.031 |
0.373 |
|
| 2013 |
Tsai Y, Feng Y, Rakshit S, Fearon E, Dempsey PJ. 236 Cell-Autonomous ADAM10 Signaling Is Required for Adenoma Initiation After APC Mutation Gastroenterology. 144: S-51-S-52. DOI: 10.1016/S0016-5085(13)60182-1 |
0.347 |
|
| 2012 |
Fearon ER, Spence JR. Cancer biology: a new RING to Wnt signaling. Current Biology : Cb. 22: R849-51. PMID 23058807 DOI: 10.1016/J.Cub.2012.08.002 |
0.401 |
|
| 2012 |
Grivennikov SI, Wang K, Mucida D, Stewart CA, Schnabl B, Jauch D, Taniguchi K, Yu GY, Osterreicher CH, Hung KE, Datz C, Feng Y, Fearon ER, Oukka M, Tessarollo L, et al. Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature. 491: 254-8. PMID 23034650 DOI: 10.1038/Nature11465 |
0.376 |
|
| 2012 |
Dou W, Mukherjee S, Li H, Venkatesh M, Wang H, Kortagere S, Peleg A, Chilimuri SS, Wang ZT, Feng Y, Fearon ER, Mani S. Alleviation of gut inflammation by Cdx2/Pxr pathway in a mouse model of chemical colitis. Plos One. 7: e36075. PMID 22815676 DOI: 10.1371/Journal.Pone.0036075 |
0.325 |
|
| 2012 |
Wu ZQ, Brabletz T, Fearon E, Willis AL, Hu CY, Li XY, Weiss SJ. Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity. Proceedings of the National Academy of Sciences of the United States of America. 109: 11312-7. PMID 22745173 DOI: 10.1073/Pnas.1203015109 |
0.486 |
|
| 2011 |
Kim NH, Kim HS, Li XY, Lee I, Choi HS, Kang SE, Cha SY, Ryu JK, Yoon D, Fearon ER, Rowe RG, Lee S, Maher CA, Weiss SJ, Yook JI. A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition. The Journal of Cell Biology. 195: 417-33. PMID 22024162 DOI: 10.1083/Jcb.201103097 |
0.436 |
|
| 2011 |
Wu R, Hu TC, Rehemtulla A, Fearon ER, Cho KR. Preclinical testing of PI3K/AKT/mTOR signaling inhibitors in a mouse model of ovarian endometrioid adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 7359-72. PMID 21903772 DOI: 10.1158/1078-0432.Ccr-11-1388 |
0.33 |
|
| 2011 |
Feng Y, Bommer GT, Zhao J, Green M, Sands E, Zhai Y, Brown K, Burberry A, Cho KR, Fearon ER. Mutant KRAS promotes hyperplasia and alters differentiation in the colon epithelium but does not expand the presumptive stem cell pool. Gastroenterology. 141: 1003-1013.e1-10. PMID 21699772 DOI: 10.1053/J.Gastro.2011.05.007 |
0.394 |
|
| 2011 |
Zhai Y, Iura A, Yeasmin S, Wiese AB, Wu R, Feng Y, Fearon ER, Cho KR. MSX2 is an oncogenic downstream target of activated WNT signaling in ovarian endometrioid adenocarcinoma. Oncogene. 30: 4152-62. PMID 21499300 DOI: 10.1038/Onc.2011.123 |
0.505 |
|
| 2011 |
Fearon ER. Molecular genetics of colorectal cancer. Annual Review of Pathology. 6: 479-507. PMID 21090969 DOI: 10.1111/J.1749-6632.1995.Tb12114.X |
0.431 |
|
| 2010 |
Takakura Y, Hinoi T, Oue N, Sasada T, Kawaguchi Y, Okajima M, Akyol A, Fearon ER, Yasui W, Ohdan H. CDX2 regulates multidrug resistance 1 gene expression in malignant intestinal epithelium. Cancer Research. 70: 6767-78. PMID 20699370 DOI: 10.1158/0008-5472.Can-09-4701 |
0.422 |
|
| 2010 |
Zhai Y, Bommer GT, Feng Y, Wiese AB, Fearon ER, Cho KR. Loss of estrogen receptor 1 enhances cervical cancer invasion. The American Journal of Pathology. 177: 884-95. PMID 20581058 DOI: 10.2353/Ajpath.2010.091166 |
0.376 |
|
| 2010 |
van de Sluis B, Mao X, Zhai Y, Groot AJ, Vermeulen JF, van der Wall E, van Diest PJ, Hofker MH, Wijmenga C, Klomp LW, Cho KR, Fearon ER, Vooijs M, Burstein E. COMMD1 disrupts HIF-1alpha/beta dimerization and inhibits human tumor cell invasion. The Journal of Clinical Investigation. 120: 2119-30. PMID 20458141 DOI: 10.1172/Jci40583 |
0.48 |
|
| 2010 |
Watson RL, Spalding AC, Zielske SP, Morgan M, Kim AC, Bommer GT, Eldar-Finkelman H, Giordano T, Fearon ER, Hammer GD, Lawrence TS, Ben-Josef E. GSK3beta and beta-catenin modulate radiation cytotoxicity in pancreatic cancer. Neoplasia (New York, N.Y.). 12: 357-65. PMID 20454507 DOI: 10.1593/Neo.92112 |
0.464 |
|
| 2010 |
Goto M, Mitra RS, Liu M, Lee J, Henson BS, Carey T, Bradford C, Prince M, Wang CY, Fearon ER, D'Silva NJ. Rap1 stabilizes beta-catenin and enhances beta-catenin-dependent transcription and invasion in squamous cell carcinoma of the head and neck. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 65-76. PMID 20028760 DOI: 10.1158/1078-0432.Ccr-09-1122 |
0.41 |
|
| 2010 |
Bommer GT, Feng Y, Iura A, Giordano TJ, Kuick R, Kadikoy H, Sikorski D, Wu R, Cho KR, Fearon ER. IRS1 regulation by Wnt/beta-catenin signaling and varied contribution of IRS1 to the neoplastic phenotype. The Journal of Biological Chemistry. 285: 1928-38. PMID 19843521 DOI: 10.1074/Jbc.M109.060319 |
0.516 |
|
| 2010 |
Tang W, Ji Q, Hao X, Li L, Jeffrey D, Fearon ER, Lawrence TS, Xu L. Abstract 2084: Tumor suppressor microRNA miR-34 inhibits human pancreatic cancer stem cells Cancer Research. 70: 2084-2084. DOI: 10.1158/1538-7445.Am10-2084 |
0.338 |
|
| 2009 |
Fearon ER. PARsing the phrase "all in for Axin"- Wnt pathway targets in cancer. Cancer Cell. 16: 366-8. PMID 19878868 DOI: 10.1016/J.Ccr.2009.10.007 |
0.485 |
|
| 2009 |
Shackleton M, Quintana E, Fearon ER, Morrison SJ. Heterogeneity in cancer: cancer stem cells versus clonal evolution. Cell. 138: 822-9. PMID 19737509 DOI: 10.1016/J.Cell.2009.08.017 |
0.375 |
|
| 2009 |
Ji Q, Hao X, Zhang M, Tang W, Yang M, Li L, Xiang D, Desano JT, Bommer GT, Fan D, Fearon ER, Lawrence TS, Xu L. MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells. Plos One. 4: e6816. PMID 19714243 DOI: 10.1371/Journal.Pone.0006816 |
0.329 |
|
| 2009 |
Vilar E, Mukherjee B, Kuick R, Raskin L, Misek DE, Taylor JM, Giordano TJ, Hanash SM, Fearon ER, Rennert G, Gruber SB. Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 2829-39. PMID 19351759 DOI: 10.1158/1078-0432.Ccr-08-2432 |
0.403 |
|
| 2009 |
Wang L, Heidt DG, Lee CJ, Yang H, Logsdon CD, Zhang L, Fearon ER, Ljungman M, Simeone DM. Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and beta-catenin stabilization. Cancer Cell. 15: 207-19. PMID 19249679 DOI: 10.1016/J.Ccr.2009.01.018 |
0.466 |
|
| 2009 |
Rowe RG, Li XY, Hu Y, Saunders TL, Virtanen I, De Herreros AG, Becker KF, Ingvarsen S, Engelholm LH, Bommer GT, Fearon ER, Weiss SJ. Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs Journal of Cell Biology. 184: 399-408. PMID 19188491 DOI: 10.1083/Jcb.200810113 |
0.383 |
|
| 2009 |
Peterson LF, Turbiak AJ, Giannola DM, Donato N, Showalter HH, Fearon ER, Talpaz M. Wnt-Pathway Directed Compound Targets Blast Crisis and Chronic Phase CML Leukemia Stem Progenitors. Blood. 114: 2168-2168. DOI: 10.1182/Blood.V114.22.2168.2168 |
0.337 |
|
| 2009 |
Xu L, Ji Q, Hao X, Tang W, Li L, DeSano JT, Fearon ER, Lawrence TS. Abstract A53: Tumor suppressor microRNA miR‐34 inhibits human pancreatic and gastric cancer stem cells Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-A53 |
0.418 |
|
| 2008 |
Sangha N, Wu R, Kuick R, Powers S, Mu D, Fiander D, Yuen K, Katabuchi H, Tashiro H, Fearon ER, Cho KR. Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations. Neoplasia (New York, N.Y.). 10: 1362-72, following 1. PMID 19048115 DOI: 10.1593/Neo.08784 |
0.405 |
|
| 2008 |
Akyol A, Hinoi T, Feng Y, Bommer GT, Glaser TM, Fearon ER. Generating somatic mosaicism with a Cre recombinase-microsatellite sequence transgene. Nature Methods. 5: 231-3. PMID 18264107 DOI: 10.1038/Nmeth.1182 |
0.312 |
|
| 2008 |
Burstein E, Fearon ER. Colitis and cancer: a tale of inflammatory cells and their cytokines. The Journal of Clinical Investigation. 118: 464-7. PMID 18219390 DOI: 10.1172/Jci34831 |
0.315 |
|
| 2007 |
Zhai Y, Kuick R, Nan B, Ota I, Weiss SJ, Trimble CL, Fearon ER, Cho KR. Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion. Cancer Research. 67: 10163-72. PMID 17974957 DOI: 10.1158/0008-5472.Can-07-2056 |
0.363 |
|
| 2007 |
Hinoi T, Akyol A, Theisen BK, Ferguson DO, Greenson JK, Williams BO, Cho KR, Fearon ER. Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation. Cancer Research. 67: 9721-30. PMID 17942902 DOI: 10.1158/0008-5472.Can-07-2735 |
0.405 |
|
| 2007 |
Bommer GT, Gerin I, Feng Y, Kaczorowski AJ, Kuick R, Love RE, Zhai Y, Giordano TJ, Qin ZS, Moore BB, MacDougald OA, Cho KR, Fearon ER. p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Current Biology : Cb. 17: 1298-307. PMID 17656095 DOI: 10.1016/J.Cub.2007.06.068 |
0.325 |
|
| 2007 |
Bommer GT, Fearon ER. Role of c-Myc in Apc mutant intestinal phenotype: case closed or time for a new beginning? Cancer Cell. 11: 391-4. PMID 17482129 DOI: 10.1016/J.Ccr.2007.04.015 |
0.426 |
|
| 2007 |
Wu R, Hendrix-Lucas N, Kuick R, Zhai Y, Schwartz DR, Akyol A, Hanash S, Misek DE, Katabuchi H, Williams BO, Fearon ER, Cho KR. Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways. Cancer Cell. 11: 321-33. PMID 17418409 DOI: 10.1016/J.Ccr.2007.02.016 |
0.483 |
|
| 2007 |
Feng Y, Bommer GT, Zhai Y, Akyol A, Hinoi T, Winer I, Lin HV, Cadigan KM, Cho KR, Fearon ER. Drosophila split ends homologue SHARP functions as a positive regulator of Wnt/beta-catenin/T-cell factor signaling in neoplastic transformation. Cancer Research. 67: 482-91. PMID 17234755 DOI: 10.1158/0008-5472.Can-06-2314 |
0.745 |
|
| 2007 |
Spalding A, Watson R, Zielske S, Kim A, Bommer G, Fearon E, Eldar-Finkelman H, Lawrence T, Ben-Josef E. Glycogen Synthase Kinase 3β Inhibition and βcatenin Activation Contribute to Enhanced Survival After Radiation in Pancreatic Cancer Cells International Journal of Radiation Oncology*Biology*Physics. 69: S608. DOI: 10.1016/J.Ijrobp.2007.07.1918 |
0.347 |
|
| 2006 |
Yook JI, Li XY, Ota I, Hu C, Kim HS, Kim NH, Cha SY, Ryu JK, Choi YJ, Kim J, Fearon ER, Weiss SJ. A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells. Nature Cell Biology. 8: 1398-406. PMID 17072303 DOI: 10.1038/Ncb1508 |
0.498 |
|
| 2006 |
Winer IS, Bommer GT, Gonik N, Fearon ER. Lysine residues Lys-19 and Lys-49 of beta-catenin regulate its levels and function in T cell factor transcriptional activation and neoplastic transformation. The Journal of Biological Chemistry. 281: 26181-7. PMID 16849322 DOI: 10.1074/Jbc.M604217200 |
0.722 |
|
| 2006 |
Hendrix ND, Wu R, Kuick R, Schwartz DR, Fearon ER, Cho KR. Fibroblast growth factor 9 has oncogenic activity and is a downstream target of Wnt signaling in ovarian endometrioid adenocarcinomas. Cancer Research. 66: 1354-62. PMID 16452189 DOI: 10.1158/0008-5472.Can-05-3694 |
0.468 |
|
| 2005 |
Rozek LS, Lipkin SM, Fearon ER, Hanash S, Giordano TJ, Greenson JK, Kuick R, Misek DE, Taylor JM, Douglas JA, Rennert G, Gruber SB. CDX2 polymorphisms, RNA expression, and risk of colorectal cancer. Cancer Research. 65: 5488-92. PMID 15994917 DOI: 10.1158/0008-5472.Can-04-3645 |
0.4 |
|
| 2005 |
Fearon ER, Cadigan KM. Cell biology. Wnt signaling glows with RNAi. Science (New York, N.Y.). 308: 801-3. PMID 15879199 DOI: 10.1126/Science.1112622 |
0.327 |
|
| 2005 |
Hinoi T, Gesina G, Akyol A, Kuick R, Hanash S, Giordano TJ, Gruber SB, Fearon ER. CDX2-regulated expression of iron transport protein hephaestin in intestinal and colonic epithelium. Gastroenterology. 128: 946-61. PMID 15825077 DOI: 10.1053/J.Gastro.2005.01.003 |
0.364 |
|
| 2005 |
Shedden KA, Kshirsagar MP, Schwartz DR, Wu R, Yu H, Misek DE, Hanash S, Katabuchi H, Ellenson LH, Fearon ER, Cho KR. Histologic type, organ of origin, and Wnt pathway status: effect on gene expression in ovarian and uterine carcinomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 2123-31. PMID 15788657 DOI: 10.1158/1078-0432.Ccr-04-2061 |
0.42 |
|
| 2005 |
Yook JI, Li XY, Ota I, Fearon ER, Weiss SJ. Wnt-dependent regulation of the E-cadherin repressor snail. The Journal of Biological Chemistry. 280: 11740-8. PMID 15647282 DOI: 10.1074/Jbc.M413878200 |
0.486 |
|
| 2005 |
Bommer GT, Jäger C, Dürr EM, Baehs S, Eichhorst ST, Brabletz T, Hu G, Fröhlich T, Arnold G, Kress DC, Göke B, Fearon ER, Kolligs FT. DRO1, a gene down-regulated by oncogenes, mediates growth inhibition in colon and pancreatic cancer cells. The Journal of Biological Chemistry. 280: 7962-75. PMID 15563452 DOI: 10.1074/Jbc.M412593200 |
0.548 |
|
| 2004 |
Li CM, Kim CE, Margolin AA, Guo M, Zhu J, Mason JM, Hensle TW, Murty VV, Grundy PE, Fearon ER, D'Agati V, Licht JD, Tycko B. CTNNB1 mutations and overexpression of Wnt/beta-catenin target genes in WT1-mutant Wilms' tumors. The American Journal of Pathology. 165: 1943-53. PMID 15579438 DOI: 10.1016/S0002-9440(10)63246-4 |
0.464 |
|
| 2004 |
Fearon ER, Cho KR. Cancer: cell survival guide. Nature. 431: 35-6. PMID 15343320 DOI: 10.1038/431035A |
0.359 |
|
| 2004 |
Mehlen P, Fearon ER. Role of the dependence receptor DCC in colorectal cancer pathogenesis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 3420-8. PMID 15310786 DOI: 10.1200/JCO.2004.02.019 |
0.361 |
|
| 2004 |
Lipkin SM, Rozek LS, Rennert G, Yang W, Chen PC, Hacia J, Hunt N, Shin B, Fodor S, Kokoris M, Greenson JK, Fearon E, Lynch H, Collins F, Gruber SB. The MLH1 D132H variant is associated with susceptibility to sporadic colorectal cancer. Nature Genetics. 36: 694-9. PMID 15184898 DOI: 10.1038/Ng1374 |
0.366 |
|
| 2004 |
Fearon ER. Defining the microsatellite instability phenotype in colorectal cancer through analysis of surrogate markers. Cancer Biology & Therapy. 3: 79-81. PMID 15112706 DOI: 10.4161/Cbt.3.1.712 |
0.341 |
|
| 2003 |
Feng Y, Lee N, Fearon ER. TIP49 regulates beta-catenin-mediated neoplastic transformation and T-cell factor target gene induction via effects on chromatin remodeling. Cancer Research. 63: 8726-34. PMID 14695187 |
0.406 |
|
| 2003 |
Shedden KA, Taylor JM, Giordano TJ, Kuick R, Misek DE, Rennert G, Schwartz DR, Gruber SB, Logsdon C, Simeone D, Kardia SL, Greenson JK, Cho KR, Beer DG, Fearon ER, et al. Accurate molecular classification of human cancers based on gene expression using a simple classifier with a pathological tree-based framework. The American Journal of Pathology. 163: 1985-95. PMID 14578198 DOI: 10.1016/S0002-9440(10)63557-2 |
0.372 |
|
| 2003 |
Hinoi T, Loda M, Fearon ER. Silencing of CDX2 expression in colon cancer via a dominant repression pathway. The Journal of Biological Chemistry. 278: 44608-16. PMID 12947088 DOI: 10.1074/Jbc.M307435200 |
0.477 |
|
| 2003 |
Kim PJ, Plescia J, Clevers H, Fearon ER, Altieri DC. Survivin and molecular pathogenesis of colorectal cancer. Lancet (London, England). 362: 205-9. PMID 12885482 DOI: 10.1016/S0140-6736(03)13910-4 |
0.482 |
|
| 2003 |
Schwartz DR, Wu R, Kardia SL, Levin AM, Huang CC, Shedden KA, Kuick R, Misek DE, Hanash SM, Taylor JM, Reed H, Hendrix N, Zhai Y, Fearon ER, Cho KR. Novel candidate targets of beta-catenin/T-cell factor signaling identified by gene expression profiling of ovarian endometrioid adenocarcinomas. Cancer Research. 63: 2913-22. PMID 12782598 |
0.334 |
|
| 2003 |
Van Mater D, Kolligs FT, Dlugosz AA, Fearon ER. Transient activation of beta -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice. Genes & Development. 17: 1219-24. PMID 12756226 DOI: 10.1101/Gad.1076103 |
0.748 |
|
| 2003 |
Fearon ER. Connecting estrogen receptor function, transcriptional repression, and E-cadherin expression in breast cancer. Cancer Cell. 3: 307-10. PMID 12726856 DOI: 10.1016/S1535-6108(03)00087-4 |
0.437 |
|
| 2003 |
Wu R, Lin L, Beer DG, Ellenson LH, Lamb BJ, Rouillard JM, Kuick R, Hanash S, Schwartz DR, Fearon ER, Cho KR. Amplification and overexpression of the L-MYC proto-oncogene in ovarian carcinomas. The American Journal of Pathology. 162: 1603-10. PMID 12707044 DOI: 10.1016/S0002-9440(10)64294-0 |
0.331 |
|
| 2002 |
Hinoi T, Lucas PC, Kuick R, Hanash S, Cho KR, Fearon ER. CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia. Gastroenterology. 123: 1565-77. PMID 12404231 DOI: 10.1053/Gast.2002.36598 |
0.351 |
|
| 2002 |
Kolligs FT, Nieman MT, Winer I, Hu G, Van Mater D, Feng Y, Smith IM, Wu R, Zhai Y, Cho KR, Fearon ER. ITF-2, a downstream target of the Wnt/TCF pathway, is activated in human cancers with beta-catenin defects and promotes neoplastic transformation. Cancer Cell. 1: 145-55. PMID 12086873 DOI: 10.1016/S1535-6108(02)00035-1 |
0.808 |
|
| 2002 |
Hajra KM, Fearon ER. Cadherin and catenin alterations in human cancer. Genes, Chromosomes & Cancer. 34: 255-68. PMID 12007186 DOI: 10.1002/Gcc.10083 |
0.805 |
|
| 2002 |
Zhai Y, Wu R, Schwartz DR, Darrah D, Reed H, Kolligs FT, Nieman MT, Fearon ER, Cho KR. Role of beta-catenin/T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas. The American Journal of Pathology. 160: 1229-38. PMID 11943708 DOI: 10.1016/S0002-9440(10)62550-3 |
0.476 |
|
| 2002 |
Leung JY, Kolligs FT, Wu R, Zhai Y, Kuick R, Hanash S, Cho KR, Fearon ER. Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling. The Journal of Biological Chemistry. 277: 21657-65. PMID 11940574 DOI: 10.1074/Jbc.M200139200 |
0.485 |
|
| 2002 |
Hajra KM, Chen DY, Fearon ER. The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Research. 62: 1613-8. PMID 11912130 |
0.78 |
|
| 2001 |
Hinoi T, Tani M, Lucas PC, Caca K, Dunn RL, Macri E, Loda M, Appelman HD, Cho KR, Fearon ER. Loss of CDX2 expression and microsatellite instability are prominent features of large cell minimally differentiated carcinomas of the colon. The American Journal of Pathology. 159: 2239-48. PMID 11733373 DOI: 10.1016/S0002-9440(10)63074-X |
0.415 |
|
| 2001 |
Giordano TJ, Shedden KA, Schwartz DR, Kuick R, Taylor JM, Lee N, Misek DE, Greenson JK, Kardia SL, Beer DG, Rennert G, Cho KR, Gruber SB, Fearon ER, Hanash S. Organ-specific molecular classification of primary lung, colon, and ovarian adenocarcinomas using gene expression profiles. The American Journal of Pathology. 159: 1231-8. PMID 11583950 DOI: 10.1016/S0002-9440(10)62509-6 |
0.368 |
|
| 2001 |
Ugai H, Li HO, Komatsu M, Tsutsui H, Song J, Shiga T, Fearon E, Murata T, Yokoyama KK. Interaction of myc-associated zinc finger protein with DCC, the product of a tumor-suppressor gene, during the neural differentiation of P19 EC cells Biochemical and Biophysical Research Communications. 286: 1087-1097. PMID 11527412 DOI: 10.1006/Bbrc.2001.5469 |
0.403 |
|
| 2001 |
Sunaga N, Kohno T, Kolligs FT, Fearon ER, Saito R, Yokota J. Constitutive activation of the Wnt signaling pathway by CTNNB1 (beta-catenin) mutations in a subset of human lung adenocarcinoma. Genes, Chromosomes & Cancer. 30: 316-21. PMID 11170292 DOI: 10.1002/1098-2264(2000)9999:9999<::Aid-Gcc1097>3.0.Co;2-9 |
0.418 |
|
| 2001 |
Sun Y, Kolligs FT, Hottiger MO, Mosavin R, Fearon ER, Nabel GJ. Regulation of beta -catenin transformation by the p300 transcriptional coactivator. Proceedings of the National Academy of Sciences of the United States of America. 97: 12613-8. PMID 11050151 DOI: 10.1073/Pnas.220158597 |
0.477 |
|
| 2000 |
Wu R, Connolly DC, Ren X, Fearon ER, Cho KR. Somatic mutations of the PPP2R1B candidate tumor suppressor gene at chromosome 11q23 are infrequent in ovarian carcinomas. Neoplasia (New York, N.Y.). 1: 311-4. PMID 10935485 DOI: 10.1038/Sj.Neo.7900042 |
0.392 |
|
| 2000 |
Kolligs FT, Kolligs B, Hajra KM, Hu G, Tani M, Cho KR, Fearon ER. gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin. Genes & Development. 14: 1319-31. PMID 10837025 |
0.797 |
|
| 2000 |
Hosono S, Gross I, English MA, Hajra KM, Fearon ER, Licht JD. E-cadherin is a WT1 target gene. The Journal of Biological Chemistry. 275: 10943-53. PMID 10753894 DOI: 10.1074/Jbc.275.15.10943 |
0.78 |
|
| 2000 |
Fearon ER. BRCA1 and E-cadherin promoter hypermethylation and gene inactivation in cancer-association or mechanism? Journal of the National Cancer Institute. 92: 515-7. PMID 10749897 DOI: 10.1093/Jnci/92.7.515 |
0.486 |
|
| 2000 |
Hilgers W, Song JJ, Haye M, Hruban RR, Kern SE, Fearon ER. Homozygous deletions inactivate DCC, but not MADH4/DPC4/SMAD4, in a subset of pancreatic and biliary cancers. Genes, Chromosomes & Cancer. 27: 353-7. PMID 10719364 DOI: 10.1002/(Sici)1098-2264(200004)27:4<353::Aid-Gcc3>3.0.Co;2-5 |
0.413 |
|
| 2000 |
Kolligs FT, Kolligs B, Hajra KM, Hu G, Tani M, Cho KR, Fearon ER. γ-Catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of β-catenin Genes & Development. 14: 1319-1331. DOI: 10.1101/Gad.14.11.1319 |
0.778 |
|
| 1999 |
Hajra KM, Ji X, Fearon ER. Extinction of E-cadherin expression in breast cancer via a dominant repression pathway acting on proximal promoter elements. Oncogene. 18: 7274-9. PMID 10602481 DOI: 10.1038/Sj.Onc.1203336 |
0.773 |
|
| 1999 |
Kolligs FT, Hu G, Dang CV, Fearon ER. Neoplastic transformation of RK3E by mutant β-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression Molecular and Cellular Biology. 19: 5696-5706. PMID 10409758 DOI: 10.1128/Mcb.19.8.5696 |
0.476 |
|
| 1999 |
Rimm DL, Caca K, Hu G, Harrison FB, Fearon ER. Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma. The American Journal of Pathology. 154: 325-9. PMID 10027390 DOI: 10.1016/S0002-9440(10)65278-9 |
0.484 |
|
| 1999 |
Fearon ER, Dang CV. Cancer genetics: Tumor suppressor meets oncogene Current Biology. 9: R62-R65. PMID 10021355 DOI: 10.1016/S0960-9822(99)80012-8 |
0.467 |
|
| 1999 |
Hu G, Fearon ER. Siah-1 N-terminal RING domain is required for proteolysis function, and C-terminal sequences regulate oligomerization and binding to target proteins. Molecular and Cellular Biology. 19: 724-32. PMID 9858595 DOI: 10.1128/Mcb.19.1.724 |
0.351 |
|
| 1998 |
Haber DA, Fearon ER. The promise of cancer genetics. Lancet (London, England). SII1-8. PMID 9606360 DOI: 10.1016/S0140-6736(98)90326-9 |
0.316 |
|
| 1998 |
Marsh DJ, Coulon V, Lunetta KL, Rocca-Serra P, Dahia PL, Zheng Z, Liaw D, Caron S, Duboué B, Lin AY, Richardson AL, Bonnetblanc JM, Bressieux JM, Cabarrot-Moreau A, Chompret A, ... ... Fearon ER, et al. Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation. Human Molecular Genetics. 7: 507-15. PMID 9467011 DOI: 10.1093/Hmg/7.3.507 |
0.374 |
|
| 1998 |
Hu G, Chung YL, Glover T, Valentine V, Look AT, Fearon ER. Characterization of human homologs of the Drosophila seven in absentia (sina) gene. Genomics. 46: 103-11. PMID 9403064 DOI: 10.1006/Geno.1997.4997 |
0.337 |
|
| 1998 |
Caca K, Kolligs F, Hu G, Hayes M, Fearon ER. Plakoglobin (γ-catenin) mutations in gastric cancer Gastroenterology. 114: A573. DOI: 10.1016/S0016-5085(98)82331-7 |
0.368 |
|
| 1997 |
Fearon ER. Human cancer syndromes: clues to the origin and nature of cancer. Science (New York, N.Y.). 278: 1043-50. PMID 9353177 DOI: 10.1126/Science.278.5340.1043 |
0.422 |
|
| 1997 |
Hu G, Zhang S, Vidal M, La Baer J, Xu T, Fearon ER. Mammalian homologs of seven in absentia regulate DCC via the ubiquitin- proteasome pathway Genes and Development. 11: 2701-2714. PMID 9334332 DOI: 10.1101/Gad.11.20.2701 |
0.353 |
|
| 1996 |
Shibata D, Reale MA, Lavin P, Silverman M, Fearon ER, Steele G, Jessup JM, Loda M, Summerhayes IC. The DCC protein and prognosis in colorectal cancer. The New England Journal of Medicine. 335: 1727-32. PMID 8929264 DOI: 10.1056/Nejm199612053352303 |
0.416 |
|
| 1996 |
Fearon ER. DCC: is there a connection between tumorigenesis and cell guidance molecules? Biochimica Et Biophysica Acta. 1288: M17-23. PMID 8876630 DOI: 10.1016/0304-419X(96)00023-6 |
0.46 |
|
| 1996 |
Fearon ER. Colorectal cancer: Molecular genetic studies and their future clinical applications Medical and Pediatric Oncology. 27: 35-40. DOI: 10.1002/(Sici)1096-911X(1996)27:1+<35::Aid-Mpo7>3.0.Co;2-O |
0.31 |
|
| 1995 |
Pierceall WE, Reale MA, Candia AF, Wright CV, Cho KR, Fearon ER. Expression of a homologue of the deleted in colorectal cancer (DCC) gene in the nervous system of developing Xenopus embryos. Developmental Biology. 166: 654-65. PMID 7813784 DOI: 10.1006/Dbio.1994.1345 |
0.389 |
|
| 1995 |
Cho KR, Fearon ER. DCC: linking tumor suppressor genes and altered cell surface interactions in cancer? Current Opinion in Genetics & Development. 5: 72-8. PMID 7749329 DOI: 10.1016/S0959-437X(95)90056-X |
0.453 |
|
| 1995 |
Cho KR, Fearon ER. DCC: linking tumour suppressor genes and altered cell surface interactions in cancer? European Journal of Cancer (Oxford, England : 1990). 1055-60. PMID 7576991 DOI: 10.1016/0959-8049(95)00128-6 |
0.451 |
|
| 1994 |
Cho KR, Oliner JD, Simons JW, Hedrick L, Fearon ER, Preisinger AC, Hedge P, Silverman GA, Vogelstein B. The DCC gene: structural analysis and mutations in colorectal carcinomas. Genomics. 19: 525-31. PMID 8188295 DOI: 10.1006/Geno.1994.1102 |
0.366 |
|
| 1994 |
Pierceall WE, Cho KR, Getzenberg RH, Reale MA, Hedrick L, Vogelstein B, Fearon ER. NIH3T3 cells expressing the deleted in colorectal cancer tumor suppressor gene product stimulate neurite outgrowth in rat PC12 pheochromocytoma cells. The Journal of Cell Biology. 124: 1017-27. PMID 8132705 DOI: 10.1083/Jcb.124.6.1017 |
0.393 |
|
| 1994 |
Hedrick L, Cho KR, Fearon ER, Wu TC, Kinzler KW, Vogelstein B. The DCC gene product in cellular differentiation and colorectal tumorigenesis. Genes & Development. 8: 1174-83. PMID 7926722 DOI: 10.1101/Gad.8.10.1174 |
0.401 |
|
| 1994 |
Fearon ER, Ekstrand BC, Hu G, Pierceall WE, Reale MA, Bigner SH. Studies of the deleted in colorectal cancer gene in normal and neoplastic tissues. Cold Spring Harbor Symposia On Quantitative Biology. 59: 637-43. PMID 7587124 DOI: 10.1101/Sqb.1994.059.01.073 |
0.448 |
|
| 1993 |
Fearon ER. K-ras gene mutation as a pathogenetic and diagnostic marker in human cancer. Journal of the National Cancer Institute. 85: 1978-80. PMID 8246279 DOI: 10.1093/Jnci/85.24.1978 |
0.35 |
|
| 1992 |
Fearon ER, Finkel T, Gillison ML, Kennedy SP, Casella JF, Tomaselli GF, Morrow JS, Van Dang C. Karyoplasmic interaction selection strategy: a general strategy to detect protein-protein interactions in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 89: 7958-62. PMID 1387709 DOI: 10.1073/Pnas.89.17.7958 |
0.316 |
|
| 1992 |
Fearon ER, Jones PA. Progressing toward a molecular description of colorectal cancer development. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 6: 2783-90. PMID 1321771 DOI: 10.1096/Fasebj.6.10.1321771 |
0.434 |
|
| 1991 |
Dang CV, Barrett J, Villa-Garcia M, Resar LMS, Kato GJ, Fearon ER. Intracellular Leucine Zipper Interactions Suggest c-Myc Hetero-Oligomerization Molecular and Cellular Biology. 11: 954-962. PMID 1990293 DOI: 10.1128/Mcb.11.2.954 |
0.306 |
|
| 1991 |
Itaya T, Fearon E, Fiesinger T, Hunt B, Vogelstein B, Frost P. Immunogenicity of a non-class I MHC expressing murine tumor transfected with the influenza virus hemagglutinin or murine interleukin-2 genes. Cancer Immunology, Immunotherapy : Cii. 33: 267-73. PMID 1905583 DOI: 10.1007/Bf01744947 |
0.321 |
|
| 1990 |
Fearon ER, Cho KR, Nigro JM, Kern SE, Simons JW, Ruppert JM, Hamilton SR, Preisinger AC, Thomas G, Kinzler KW. Identification of a chromosome 18q gene that is altered in colorectal cancers. Science (New York, N.Y.). 247: 49-56. PMID 2294591 DOI: 10.1126/Science.2294591 |
0.418 |
|
| 1990 |
Baker SJ, Markowitz S, Fearon ER, Willson JK, Vogelstein B. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science (New York, N.Y.). 249: 912-5. PMID 2144057 DOI: 10.1126/Science.2144057 |
0.38 |
|
| 1990 |
Fearon ER, Pardoll DM, Itaya T, Golumbek P, Levitsky HI, Simons JW, Karasuyama H, Vogelstein B, Frost P. Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response. Cell. 60: 397-403. PMID 2137372 DOI: 10.1016/0092-8674(90)90591-2 |
0.312 |
|
| 1989 |
Schackert HK, Itaya T, Schackert G, Fearon E, Vogelstein B, Frost P. Systemic immunity against a murine colon tumor (CT-26) produced by immunization with syngeneic cells expressing a transfected viral gene product. International Journal of Cancer. 43: 823-7. PMID 2714886 DOI: 10.1002/Ijc.2910430514 |
0.311 |
|
| 1989 |
Baker SJ, Fearon ER, Nigro JM, Hamilton SR, Preisinger AC, Jessup JM, vanTuinen P, Ledbetter DH, Barker DF, Nakamura Y, White R, Vogelstein B. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science (New York, N.Y.). 244: 217-21. PMID 2649981 DOI: 10.1126/Science.2649981 |
0.347 |
|
| 1989 |
Vogelstein B, Fearon ER, Kern SE, Hamilton SR, Preisinger AC, Nakamura Y, White R. Allelotype of colorectal carcinomas. Science (New York, N.Y.). 244: 207-11. PMID 2565047 DOI: 10.1126/Science.2565047 |
0.327 |
|
| 1988 |
Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Preisinger AC, Leppert M, Nakamura Y, White R, Smits AM, Bos JL. Genetic alterations during colorectal-tumor development. The New England Journal of Medicine. 319: 525-32. PMID 2841597 DOI: 10.1056/Nejm198809013190901 |
0.369 |
|
| 1987 |
Bos JL, Vries MVd, Van Der Eb AJ, Fearon ER, Vogelstein B, Hamilton SR, Van Boom JH. Prevalence of ras gene mutations in human colorectal cancers Nature. 327: 293-297. PMID 3587348 DOI: 10.1038/327293A0 |
0.364 |
|
| 1987 |
Fearon ER, Hamilton SR, Vogelstein B. Clonal analysis of human colorectal tumors. Science (New York, N.Y.). 238: 193-7. PMID 2889267 DOI: 10.1126/Science.2889267 |
0.317 |
|
| 1987 |
Baylin S, Fearon E, Vogelstein B, de Bustros A, Sharkis S, Burke P, Staal S, Nelkin B. Hypermethylation of the 5' region of the calcitonin gene is a property of human lymphoid and acute myeloid malignancies Blood. 70: 412-417. DOI: 10.1182/Blood.V70.2.412.Bloodjournal702412 |
0.332 |
|
| 1985 |
Fearon ER, Feinberg AP, Hamilton SH, Vogelstein B. Loss of genes on the short arm of chromosome 11 in bladder cancer. Nature. 318: 377-80. PMID 2999610 DOI: 10.1038/318377A0 |
0.328 |
|
| 1985 |
Vogelstein B, Fearon ER, Hamilton SR, Feinberg AP. Use of restriction fragment length polymorphisms to determine the clonal origin of human tumors. Science (New York, N.Y.). 227: 642-5. PMID 2982210 DOI: 10.1126/Science.2982210 |
0.325 |
|
| 1984 |
Fearon ER, Vogelstein B, Feinberg AP. Somatic deletion and duplication of genes on chromosome 11 in Wilms' tumours. Nature. 309: 176-8. PMID 6325939 DOI: 10.1038/309176A0 |
0.311 |
|
| 1983 |
Antonarakis SE, Phillips JA, Mallonee RL, Kazazian HH, Fearon ER, Waber PG, Kronenberg HM, Ullrich A, Meyers DA. Beta-globin locus is linked to the parathyroid hormone (PTH) locus and lies between the insulin and PTH loci in man. Proceedings of the National Academy of Sciences of the United States of America. 80: 6615-9. PMID 6314332 DOI: 10.1073/Pnas.80.21.6615 |
0.327 |
|
| 1983 |
Fearon E, Kazazian HJ, Waber P, Lee J, Antonarakis S, Orkin S, Vanin E, Henthorn P, Grosveld F, Scott A, Buchanan G. The entire beta-globin gene cluster is deleted in a form of gamma delta beta-thalassemia Blood. 61: 1269-1274. DOI: 10.1182/Blood.V61.6.1269.Bloodjournal6161269 |
0.367 |
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