| Year |
Citation |
Score |
| 2023 |
Pham VN, Bruemmer KJ, Toh JDW, Ge EJ, Tenney L, Ward CC, Dingler FA, Millington CL, Garcia-Prieto CA, Pulos-Holmes MC, Ingolia NT, Pontel LB, Esteller M, Patel KJ, Nomura DK, et al. Formaldehyde regulates -adenosylmethionine biosynthesis and one-carbon metabolism. Science (New York, N.Y.). 382: eabp9201. PMID 37917677 DOI: 10.1126/science.abp9201 |
0.495 |
|
| 2023 |
Moon P, Zammit C, Shao Q, Boike L, Dovala D, Henning NJ, Knapp M, Spradlin JN, Ward CC, Wolleb H, Fuller D, Blake G, Murphy JP, Wang F, Lu Y, et al. Discovery of Potent Pyrazoline-Based Covalent SARS-CoV-2 Main Protease Inhibitors. Chembiochem : a European Journal of Chemical Biology. e202300116. PMID 37069799 DOI: 10.1002/cbic.202300116 |
0.683 |
|
| 2022 |
Henning NJ, Boike L, Spradlin JN, Ward CC, Liu G, Zhang E, Belcher BP, Brittain SM, Hesse MJ, Dovala D, McGregor LM, Valdez Misiolek R, Plasschaert LW, Rowlands DJ, Wang F, et al. Deubiquitinase-targeting chimeras for targeted protein stabilization. Nature Chemical Biology. PMID 35210618 DOI: 10.1038/s41589-022-00971-2 |
0.656 |
|
| 2021 |
Belcher BP, Ward CC, Nomura DK. Ligandability of E3 Ligases for Targeted Protein Degradation Applications. Biochemistry. PMID 34473924 DOI: 10.1021/acs.biochem.1c00464 |
0.772 |
|
| 2021 |
Biering SB, Van Dis E, Wehri E, Yamashiro LH, Nguyenla X, Dugast-Darzacq C, Graham TGW, Stroumza JR, Golovkine GR, Roberts AW, Fines DM, Spradlin JN, Ward CC, Bajaj T, Dovala D, et al. Screening a Library of FDA-Approved and Bioactive Compounds for Antiviral Activity against SARS-CoV-2. Acs Infectious Diseases. PMID 34129317 DOI: 10.1021/acsinfecdis.1c00017 |
0.734 |
|
| 2020 |
Sponton CH, Hosono T, Taura J, Jedrychowski MP, Yoneshiro T, Wang Q, Takahashi M, Matsui Y, Ikeda K, Oguri Y, Tajima K, Shinoda K, Pradhan RN, Chen Y, Brown Z, ... ... Ward CC, et al. The regulation of glucose and lipid homeostasis via PLTP as a mediator of BAT-liver communication. Embo Reports. e49828. PMID 32672883 DOI: 10.15252/Embr.201949828 |
0.725 |
|
| 2019 |
Chung CY, Shin HR, Berdan CA, Ford B, Ward CC, Olzmann JA, Zoncu R, Nomura DK. Covalent targeting of the vacuolar H-ATPase activates autophagy via mTORC1 inhibition. Nature Chemical Biology. PMID 31285595 DOI: 10.1038/S41589-019-0308-4 |
0.78 |
|
| 2019 |
Spradlin JN, Hu X, Ward CC, Brittain SM, Jones MD, Ou L, To M, Proudfoot A, Ornelas E, Woldegiorgis M, Olzmann JA, Bussiere DE, Thomas JR, Tallarico JA, McKenna JM, et al. Harnessing the anti-cancer natural product nimbolide for targeted protein degradation. Nature Chemical Biology. PMID 31209351 DOI: 10.1038/S41589-019-0304-8 |
0.803 |
|
| 2019 |
Ward CC, Kleinman JI, Brittain SM, Lee PS, Chung CYS, Kim K, Petri Y, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Nomura DK. Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. Acs Chemical Biology. PMID 31059647 DOI: 10.1021/Acschembio.8B01083 |
0.693 |
|
| 2018 |
Magtanong L, Ko PJ, To M, Cao JY, Forcina GC, Tarangelo A, Ward CC, Cho K, Patti GJ, Nomura DK, Olzmann JA, Dixon SJ. Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State. Cell Chemical Biology. PMID 30686757 DOI: 10.1016/J.Chembiol.2018.11.016 |
0.48 |
|
| 2017 |
Grossman EA, Ward CC, Spradlin JN, Bateman LA, Huffman TR, Miyamoto DK, Kleinman JI, Nomura DK. Covalent Ligand Discovery against Druggable Hotspots Targeted by Anti-cancer Natural Products. Cell Chemical Biology. PMID 28919038 DOI: 10.1016/J.Chembiol.2017.08.013 |
0.723 |
|
| 2017 |
Ward CC, Kleinman JI, Nomura DK. NHS-Esters as Versatile Reactivity-Based Probes for Mapping Proteome-Wide Ligandable Hotspots. Acs Chemical Biology. PMID 28445029 DOI: 10.1021/Acschembio.7B00125 |
0.633 |
|
| 2016 |
Roberts AM, Ward CC, Nomura DK. Activity-based protein profiling for mapping and pharmacologically interrogating proteome-wide ligandable hotspots. Current Opinion in Biotechnology. 43: 25-33. PMID 27568596 DOI: 10.1016/J.Copbio.2016.08.003 |
0.817 |
|
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