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Aik T. Ooi, Ph.D. - Publications

Affiliations: 
2007 Pharmaceutical Sciences University of Arizona, Tucson, AZ 
Area:
Molecular Biology
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Dhingra DM, Ooi AT, Ruff DW. Simultaneous DNA, RNA, and Protein Analysis from Single Cells Using a High-Throughput Microfluidic Workflow for Resolution of Genotype-to-Phenotype Modalities. Methods in Molecular Biology (Clifton, N.J.). 2386: 289-307. PMID 34766277 DOI: 10.1007/978-1-0716-1771-7_17  0.402
2021 Dillon LW, Ghannam J, Nosiri C, Gui G, Goswami M, Calvo KR, Lindblad KE, Oetjen KA, Wilkerson M, Soltis AR, Sukumar G, Dalgard CL, Thompson J, Valdez J, DeStefano CB, ... ... Ooi A, et al. Personalized Single-Cell Proteogenomics to Distinguish Acute Myeloid Leukemia from Non-Malignant Clonal Hematopoiesis. Cancer Discovery. 2: 319-325. PMID 34258102 DOI: 10.1158/2643-3230.BCD-21-0046  0.31
2020 Mereu E, Lafzi A, Moutinho C, Ziegenhain C, McCarthy DJ, Álvarez-Varela A, Batlle E, Sagar, Grün D, Lau JK, Boutet SC, Sanada C, Ooi A, Jones RC, Kaihara K, et al. Benchmarking single-cell RNA-sequencing protocols for cell atlas projects. Nature Biotechnology. 38: 747-755. PMID 32518403 DOI: 10.1038/S41587-020-0469-4  0.355
2020 Ruff D, Dhingra D, Mendez P, Ooi A, Sciambi A, Wang S. Abstract LB-316: Innovative multimodal single-cell workflow to interrogate cellular responses to cancer therapy Cancer Research. 80. DOI: 10.1158/1538-7445.Am2020-Lb-316  0.469
2020 Ooi A, Mendez P, Dhingra D, Beard N, Ruff D. Abstract 5910: Single-cell multiomic analysis of SNV, CNV, and protein expression Cancer Research. 80: 5910-5910. DOI: 10.1158/1538-7445.Am2020-5910  0.503
2020 Mendez P, Dhingra D, Ooi A, Wang S, Gulati S, Beard N, Manivannan M, Björkman J, Kubista M, Landberg G, Ruff D, Ståhlberg A. Abstract 2506: Simultaneous DNA, RNA and protein analysis from single cells using a high-throughput microfluidic workflow for resolution of genotype-to-phenotype modalities Cancer Research. 80: 2506-2506. DOI: 10.1158/1538-7445.Am2020-2506  0.506
2020 Dhingra D, Mendez P, Ooi A, Wang S, Gulati S, Sciambi A, Ruff D. Abstract 219: A high throughput single-cell workflow for paired genomic and phenotypic analysis Cancer Research. 80: 219-219. DOI: 10.1158/1538-7445.Am2020-219  0.487
2019 Ooi AT, Ruff DW. Simultaneous Targeted Detection of Proteins and RNAs in Single Cells. Methods in Molecular Biology (Clifton, N.J.). 1979: 379-392. PMID 31028649 DOI: 10.1007/978-1-4939-9240-9_22  0.36
2019 Sanada CD, Ooi AT. Single-Cell Dosing and mRNA Sequencing of Suspension and Adherent Cells Using the Polaris System. Methods in Molecular Biology (Clifton, N.J.). 1979: 185-195. PMID 31028639 DOI: 10.1007/978-1-4939-9240-9_12  0.384
2019 Miles LA, Bowman RL, Merlinsky TR, Ooi A, Mendez P, Famulare C, Patel MA, Bolton K, Palmisiano N, Carroll MP, Papaemmanuil E, Zehir A, Meyer SE, Viny AD, Levine RL. Single Cell DNA Sequencing Identifies Combinatorial Mutation Patterns and Clonal Architecture in Myeloid Malignancies Blood. 134: 913-913. DOI: 10.1182/Blood-2019-128763  0.331
2019 Demaree B, Delley C, Peretz C, Vasudevan H, Ruff D, Ooi A, Smith CC, Abate A. Combined Single-Cell DNA Genotyping and Protein Quantification (DAb-seq) in Acute Myeloid Leukemias Reveals Distinct Immunophenotypic Subsets Among Pathogenic Clones Blood. 134: 2088-2088. DOI: 10.1182/Blood-2019-127048  0.475
2018 Walser TC, Jing Z, Tran LM, Lin YQ, Yakobian N, Wang G, Krysan K, Zhu LX, Sharma S, Lee MH, Belperio JA, Ooi AT, Gomperts BN, Shay JW, Larsen JE, et al. Silencing the Snail-dependent RNA splice regulator ESRP1 drives malignant transformation of human pulmonary epithelial cells. Cancer Research. PMID 29431637 DOI: 10.1158/0008-5472.Can-17-0315  0.366
2017 Gong H, Wang X, Liu B, Boutet S, Holcomb I, Dakshinamoorthy G, Ooi A, Sanada C, Sun G, Ramakrishnan R. Single-cell protein-mRNA correlation analysis enabled by multiplexed dual-analyte co-detection. Scientific Reports. 7: 2776. PMID 28584233 DOI: 10.1038/S41598-017-03057-5  0.352
2017 Gong H, Wang X, Liu B, Holcomb I, Dakshinamoorthy G, Ooi A, Sun G, Ramakrishnan R. Abstract 4497: Single-cell protein-mRNA co-detection to reveals subpopulation-specific correlation patterns Cancer Research. 77: 4497-4497. DOI: 10.1158/1538-7445.Am2017-4497  0.339
2016 Ramalingam N, Fowler B, Szpankowski L, Leyrat AA, Hukari K, Maung MT, Yorza W, Norris M, Cesar C, Shuga J, Gonzales ML, Sanada CD, Wang X, Yeung R, Hwang W, ... ... Ooi A, et al. Fluidic Logic Used in a Systems Approach to Enable Integrated Single-Cell Functional Analysis. Frontiers in Bioengineering and Biotechnology. 4: 70. PMID 27709111 DOI: 10.3389/Fbioe.2016.00070  0.378
2016 Gong H, Holcomb I, Ooi A, Wang X, Majonis D, Unger MA, Ramakrishnan R. Simple Method To Prepare Oligonucleotide-Conjugated Antibodies and Its Application in Multiplex Protein Detection in Single Cells. Bioconjugate Chemistry. PMID 26689321 DOI: 10.1021/Acs.Bioconjchem.5B00613  0.395
2016 Gong H, Holcomb I, Ooi A, Wang X, Majonis D, Unger M, Ramakrishnan R. Abstract B18: A simple method to prepare oligonucleotide-conjugated antibodies for multiplex protein detection Cancer Research. 76. DOI: 10.1158/1538-7445.Fbcr15-B18  0.37
2016 Liu B, Dakshinamoorthy G, Gong H, Ooi A, Li N, Unger M, Holcomb I, Ramakrishnan R. Abstract LB-147: Simultaneous profiling of mRNA and protein in single human induced pluripotent stem cells Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-147  0.43
2016 Walser TC, Jing Z, Tran L, Lin Y, Zhu L, Sharma S, Ooi A, Gomperts BN, Shay JW, Larsen JE, Gao B, Minna JD, Fishbein MC, Dubinett SM. Abstract 5170: Snail-dependent ESRP1 silencing drives malignant conversion of human pulmonary epithelial cells Cancer Research. 76: 5170-5170. DOI: 10.1158/1538-7445.Am2016-5170  0.305
2015 Ooi AT, Gomperts BN. Molecular Pathways: Targeting Cellular Energy Metabolism in Cancer via Inhibition of SLC2A1 and LDHA. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2440-4. PMID 25838393 DOI: 10.1158/1078-0432.Ccr-14-1209  0.339
2014 Ooi AT, Gower AC, Zhang KX, Vick JL, Hong L, Nagao B, Wallace WD, Elashoff DA, Walser TC, Dubinett SM, Pellegrini M, Lenburg ME, Spira A, Gomperts BN. Molecular profiling of premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis. Cancer Prevention Research (Philadelphia, Pa.). 7: 487-95. PMID 24618292 DOI: 10.1158/1940-6207.Capr-13-0372  0.337
2014 Hegab AE, Ha VL, Bisht B, Darmawan DO, Ooi AT, Zhang KX, Paul MK, Kim YS, Gilbert JL, Attiga YS, Alva-Ornelas JA, Nickerson DW, Gomperts BN. Aldehyde dehydrogenase activity enriches for proximal airway basal stem cells and promotes their proliferation. Stem Cells and Development. 23: 664-75. PMID 24171691 DOI: 10.1089/Scd.2013.0295  0.359
2013 Ooi AT, Gower A, Zhang K, Vick J, Hong L, Fishbein M, Nagao B, Wallace WD, Elashoff D, Lenburg M, Dubinett S, Spira A, Gomperts B. Abstract 1063: Examining early events in carcinogenesis by profiling premalignant lesions in the airways of patients with lung squamous cell carcinomas. Cancer Research. 73: 1063-1063. DOI: 10.1158/1538-7445.Am2013-1063  0.358
2012 Hegab AE, Ha VL, Darmawan DO, Gilbert JL, Ooi AT, Attiga YS, Bisht B, Nickerson DW, Gomperts BN. Isolation and in vitro characterization of basal and submucosal gland duct stem/progenitor cells from human proximal airways. Stem Cells Translational Medicine. 1: 719-24. PMID 23197663 DOI: 10.5966/Sctm.2012-0056  0.357
2011 Hegab AE, Ha VL, Gilbert JL, Zhang KX, Malkoski SP, Chon AT, Darmawan DO, Bisht B, Ooi AT, Pellegrini M, Nickerson DW, Gomperts BN. Novel stem/progenitor cell population from murine tracheal submucosal gland ducts with multipotent regenerative potential. Stem Cells (Dayton, Ohio). 29: 1283-93. PMID 21710468 DOI: 10.1002/Stem.680  0.366
2010 Ooi AT, Mah V, Nickerson DW, Gilbert JL, Ha VL, Hegab AE, Horvath S, Alavi M, Maresh EL, Chia D, Gower AC, Lenburg ME, Spira A, Solis LM, Wistuba II, et al. Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer. Cancer Research. 70: 6639-48. PMID 20710044 DOI: 10.1158/0008-5472.Can-10-0455  0.355
2010 Walser TC, Krysan K, Gardner BK, Hong L, Fishbein MC, Goodglick L, Ooi A, Gomperts BN, Larsen JE, Minna JD, Dubinett SM. Abstract CN12-03: The inflammation-EMT-cancer initiating cell axis in the pathogenesis of lung cancer: Breaking ground in the pursuit of targeted chemoprevention Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-Cn12-03  0.377
2006 Ghosh I, Stains CI, Ooi AT, Segal DJ. Direct detection of double-stranded DNA: Molecular methods and applications for DNA diagnostics. Molecular Biosystems. 2: 551-60. PMID 17216036 DOI: 10.1039/B611169F  0.503
2006 Ooi AT, Stains CI, Ghosh I, Segal DJ. Sequence-enabled reassembly of beta-lactamase (SEER-LAC): a sensitive method for the detection of double-stranded DNA. Biochemistry. 45: 3620-5. PMID 16533044 DOI: 10.1021/Bi0517032  0.489
2006 Ooi AT, Stains CI, Ghosh I, Segal DJ. 973. SEquence-Enabled Reassembly of β- Lactamase (SEER-LAC): A Sensitive Method for the Detection of Double-Stranded DNA Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.1065  0.489
2005 Stains CI, Porter JR, Ooi AT, Segal DJ, Ghosh I. DNA sequence-enabled reassembly of the green fluorescent protein. Journal of the American Chemical Society. 127: 10782-3. PMID 16076155 DOI: 10.1021/Ja051969W  0.476
2004 Dai J, Punchihewa C, Mistry P, Ooi AT, Yang D. Novel DNA bis-intercalation by MLN944, a potent clinical bisphenazine anticancer drug. The Journal of Biological Chemistry. 279: 46096-103. PMID 15317822 DOI: 10.1074/Jbc.M404053200  0.522
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