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Jon Staley - Publications

Affiliations: 
University of Chicago, Chicago, IL 
Area:
mRNA processing
Website:
http://mgcb.uchicago.edu/faculty/staley/index.html

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Toroney R, Nielsen KH, Staley JP. Termination of pre-mRNA splicing requires that the ATPase and RNA unwindase Prp43p acts on the catalytic snRNA U6. Genes & Development. PMID 31558568 DOI: 10.1101/Gad.328294.119  0.747
2017 He Y, Staley JP, Andersen GR, Nielsen KH. Structure of DEAH/RHA ATPase Prp43p bound to RNA implicates a pair of hairpins and motif Va in translocation along RNA. Rna (New York, N.Y.). PMID 28416566 DOI: 10.1261/Rna.060954.117  0.689
2016 Shao Y, Huang H, Qin D, Li NS, Koide A, Staley JP, Koide S, Kossiakoff AA, Piccirilli JA. Specific Recognition of a Single-stranded RNA Sequence by a Synthetic Antibody Fragment. Journal of Molecular Biology. PMID 27593161 DOI: 10.1016/J.Jmb.2016.08.029  0.322
2016 Soucek S, Zeng Y, Bellur DL, Bergkessel M, Morris KJ, Deng Q, Duong D, Seyfried NT, Guthrie C, Staley JP, Fasken MB, Corbett AH. The Evolutionarily-conserved Polyadenosine RNA Binding Protein, Nab2, Cooperates with Splicing Machinery to Regulate the Fate of pre-mRNA. Molecular and Cellular Biology. PMID 27528618 DOI: 10.1128/Mcb.00402-16  0.815
2016 Semlow DR, Blanco MR, Walter NG, Staley JP. Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites. Cell. 164: 985-98. PMID 26919433 DOI: 10.1016/J.Cell.2016.01.025  0.819
2015 Qin D, Huang L, Wlodaver A, Andrade J, Staley JP. Sequencing of lariat termini in S. cerevisiae reveals 5' splice sites, branch points, and novel splicing events. Rna (New York, N.Y.). PMID 26647463 DOI: 10.1261/Rna.052829.115  0.35
2015 Liu Y, Chen X, Qin B, Zhao K, Zhao Q, Staley JP, Zhao C. Knocking Down Snrnp200 Initiates Demorphogenesis of Rod Photoreceptors in Zebrafish. Journal of Ophthalmology. 2015: 816329. PMID 26137319 DOI: 10.1155/2015/816329  0.324
2014 Fica SM, Mefford MA, Piccirilli JA, Staley JP. Evidence for a group II intron-like catalytic triplex in the spliceosome. Nature Structural & Molecular Biology. 21: 464-71. PMID 24747940 DOI: 10.1038/Nsmb.2815  0.755
2014 Wlodaver AM, Staley JP. The DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome. Rna (New York, N.Y.). 20: 282-94. PMID 24442613 DOI: 10.1261/rna.042598.113  0.449
2013 Fica SM, Tuttle N, Novak T, Li NS, Lu J, Koodathingal P, Dai Q, Staley JP, Piccirilli JA. RNA catalyses nuclear pre-mRNA splicing. Nature. 503: 229-34. PMID 24196718 DOI: 10.1038/Nature12734  0.796
2013 Koodathingal P, Staley JP. Splicing fidelity: DEAD/H-box ATPases as molecular clocks. Rna Biology. 10: 1073-9. PMID 23770752 DOI: 10.4161/rna.25245  0.444
2013 Schellenberg MJ, Wu T, Ritchie DB, Fica S, Staley JP, Atta KA, LaPointe P, MacMillan AM. A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nature Structural & Molecular Biology. 20: 728-34. PMID 23686287 DOI: 10.1038/Nsmb.2556  0.814
2013 Kannan R, Hartnett S, Voelker RB, Berglund JA, Staley JP, Baumann P. Intronic sequence elements impede exon ligation and trigger a discard pathway that yields functional telomerase RNA in fission yeast. Genes & Development. 27: 627-38. PMID 23468430 DOI: 10.1101/gad.212738.112  0.428
2012 Nielsen KH, Staley JP. Spliceosome activation: U4 is the path, stem I is the goal, and Prp8 is the keeper. Let's cheer for the ATPase Brr2! Genes & Development. 26: 2461-7. PMID 23154979 DOI: 10.1101/Gad.207514.112  0.736
2012 Semlow DR, Staley JP. Staying on message: ensuring fidelity in pre-mRNA splicing. Trends in Biochemical Sciences. 37: 263-73. PMID 22564363 DOI: 10.1016/j.tibs.2012.04.001  0.802
2012 Kim Guisbert KS, Zhang Y, Flatow J, Hurtado S, Staley JP, Lin S, Sontheimer EJ. Meiosis-induced alterations in transcript architecture and noncoding RNA expression in S. cerevisiae. Rna (New York, N.Y.). 18: 1142-53. PMID 22539527 DOI: 10.1261/Rna.030510.111  0.786
2010 Koodathingal P, Novak T, Piccirilli JA, Staley JP. The DEAH box ATPases Prp16 and Prp43 cooperate to proofread 5' splice site cleavage during pre-mRNA splicing. Molecular Cell. 39: 385-95. PMID 20705241 DOI: 10.1016/J.Molcel.2010.07.014  0.438
2010 Mayas RM, Maita H, Semlow DR, Staley JP. Spliceosome discards intermediates via the DEAH box ATPase Prp43p. Proceedings of the National Academy of Sciences of the United States of America. 107: 10020-5. PMID 20463285 DOI: 10.1073/Pnas.0906022107  0.753
2009 Zhao C, Bellur DL, Lu S, Zhao F, Grassi MA, Bowne SJ, Sullivan LS, Daiger SP, Chen LJ, Pang CP, Zhao K, Staley JP, Larsson C. Autosomal-dominant retinitis pigmentosa caused by a mutation in SNRNP200, a gene required for unwinding of U4/U6 snRNAs. American Journal of Human Genetics. 85: 617-27. PMID 19878916 DOI: 10.1016/J.Ajhg.2009.09.020  0.31
2009 Mefford MA, Staley JP. Evidence that U2/U6 helix I promotes both catalytic steps of pre-mRNA splicing and rearranges in between these steps. Rna (New York, N.Y.). 15: 1386-97. PMID 19458033 DOI: 10.1261/Rna.1582609  0.814
2009 Staley JP, Woolford JL. Assembly of ribosomes and spliceosomes: complex ribonucleoprotein machines. Current Opinion in Cell Biology. 21: 109-18. PMID 19167202 DOI: 10.1016/j.ceb.2009.01.003  0.356
2008 Bellare P, Small EC, Huang X, Wohlschlegel JA, Staley JP, Sontheimer EJ. A role for ubiquitin in the spliceosome assembly pathway. Nature Structural & Molecular Biology. 15: 444-51. PMID 18425143 DOI: 10.1038/Nsmb.1401  0.764
2007 Hilliker AK, Mefford MA, Staley JP. U2 toggles iteratively between the stem IIa and stem IIc conformations to promote pre-mRNA splicing. Genes & Development. 21: 821-34. PMID 17403782 DOI: 10.1101/Gad.1536107  0.761
2006 Mayas RM, Staley JP. DEAD on. Nature Structural & Molecular Biology. 13: 954-5. PMID 17082789 DOI: 10.1038/nsmb1106-954  0.711
2006 Small EC, Leggett SR, Winans AA, Staley JP. The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase. Molecular Cell. 23: 389-99. PMID 16885028 DOI: 10.1016/J.Molcel.2006.05.043  0.755
2006 Mayas RM, Maita H, Staley JP. Exon ligation is proofread by the DExD/H-box ATPase Prp22p. Nature Structural & Molecular Biology. 13: 482-90. PMID 16680161 DOI: 10.1038/Nsmb1093  0.804
2006 Leeds NB, Small EC, Hiley SL, Hughes TR, Staley JP. The splicing factor Prp43p, a DEAH box ATPase, functions in ribosome biogenesis. Molecular and Cellular Biology. 26: 513-22. PMID 16382143 DOI: 10.1128/Mcb.26.2.513-522.2006  0.771
2004 Hilliker AK, Staley JP. Multiple functions for the invariant AGC triad of U6 snRNA. Rna (New York, N.Y.). 10: 921-8. PMID 15146076 DOI: 10.1261/Rna.7310704  0.791
2001 Chen JYF, Stands L, Staley JP, Jackups RR, Latus LJ, Chang TH. Specific alterations of U1-C protein or U1 Small nuclear RNA can eliminate the requirement of Prp28p, an essential DEAD Box splicing factor Molecular Cell. 7: 227-232. PMID 11172727 DOI: 10.1016/S1097-2765(01)00170-8  0.392
1999 Staley JP, Guthrie C. An RNA switch at the 5' splice site requires ATP and the DEAD box protein Prp28p. Molecular Cell. 3: 55-64. PMID 10024879 DOI: 10.1016/S1097-2765(00)80174-4  0.643
1998 Staley JP, Guthrie C. Mechanical devices of the spliceosome: motors, clocks, springs, and things. Cell. 92: 315-26. PMID 9476892 DOI: 10.1016/S0092-8674(00)80925-3  0.42
1994 Staley JP, Kim PS. Formation of a native-like subdomain in a partially folded intermediate of bovine pancreatic trypsin inhibitor Protein Science. 3: 1822-1832. PMID 7531529 DOI: 10.1002/Pro.5560031021  0.393
1992 Staley JP, Kim PS. Complete folding of bovine pancreatic trypsin inhibitor with only a single disulfide bond Proceedings of the National Academy of Sciences of the United States of America. 89: 1519-1523. PMID 1371875 DOI: 10.1073/Pnas.89.5.1519  0.371
1990 Staley JP, Kim PS. Role of a subdomain in the folding of bovine pancreatic trypsin inhibitor Nature. 344: 685-688. PMID 1691452 DOI: 10.1038/344685A0  0.377
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