Robert G. Gourdie - Publications

Affiliations: 
Medical University of South Carolina, Charleston, SC, United States 
Area:
heart connexins

137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Adams WP, Raisch TB, Zhao Y, Davalos R, Barrett S, King DR, Bain CB, Colucci-Chang K, Blair GA, Hanlon A, Lozano A, Veeraraghavan R, Wan X, Deschene I, Smyth JW, ... ... Gourdie RG, et al. Extracellular Perinexal Separation Is a Principal Determinant of Cardiac Conduction. Circulation Research. PMID 37681314 DOI: 10.1161/CIRCRESAHA.123.322567  0.646
2022 Teng ACT, Gu L, Di Paola M, Lakin R, Williams ZJ, Au A, Chen W, Callaghan NI, Zadeh FH, Zhou YQ, Fatah M, Chatterjee D, Jourdan LJ, Liu J, Simmons CA, ... ... Gourdie RG, et al. Tmem65 is critical for the structure and function of the intercalated discs in mouse hearts. Nature Communications. 13: 6166. PMID 36257954 DOI: 10.1038/s41467-022-33303-y  0.346
2021 Wu X, Hoeker GS, Blair G, King DR, Gourdie RG, Weinberg SH, Poelzing S. Hypernatremia and Intercalated Disc Edema Synergistically Exacerbate Long QT Syndrome Type 3 Phenotype. American Journal of Physiology. Heart and Circulatory Physiology. PMID 34623182 DOI: 10.1152/ajpheart.00366.2021  0.705
2021 Olejnickova V, Kocka M, Kvasilova A, Kolesova H, Dziacky A, Gidor T, Gidor L, Sankova B, Gregorovicova M, Gourdie RG, Sedmera D. Gap Junctional Communication via Connexin43 between Purkinje Fibers and Working Myocytes Explains the Epicardial Activation Pattern in the Postnatal Mouse Left Ventricle. International Journal of Molecular Sciences. 22. PMID 33804428 DOI: 10.3390/ijms22052475  0.326
2020 Hoeker GS, James CC, Tegge AN, Gourdie RG, Smyth JW, Poelzing S. Attenuating loss of cardiac conduction during no-flow ischemia through changes in perfusate sodium and calcium. American Journal of Physiology. Heart and Circulatory Physiology. PMID 32678707 DOI: 10.1152/Ajpheart.00112.2020  0.618
2019 Jiang J, Hoagland D, Palatinus JA, He H, Iyyathurai J, Jourdan LJ, Bultynck G, Wang Z, Zhang Z, Schey K, Poelzing S, McGowan FX, Gourdie RG. Interaction of α Carboxyl Terminus 1 Peptide With the Connexin 43 Carboxyl Terminus Preserves Left Ventricular Function After Ischemia-Reperfusion Injury. Journal of the American Heart Association. 8: e012385. PMID 31422747 DOI: 10.1161/Jaha.119.012385  0.802
2019 Schultz F, Swiatlowska P, Alvarez-Laviada A, Sanchez-Alonso JL, Song Q, de Vries AAF, Pijnappels DA, Ongstad E, Braga VMM, Entcheva E, Gourdie RG, Miragoli M, Gorelik J. Cardiomyocyte-myofibroblast contact dynamism is modulated by connexin-43. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802740RR. PMID 31253057 DOI: 10.1096/Fj.201802740Rr  0.354
2019 George SA, Hoeker G, Calhoun P, Entz M, Raisch TB, King DR, Khan M, Baker CE, Gourdie RG, Smyth JW, Nielsen MS, Poelzing S. Modulating Cardiac Conduction during Metabolic Ischemia with Perfusate Sodium and Calcium in Guinea Pig Hearts. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30707595 DOI: 10.1152/Ajpheart.00083.2018  0.644
2019 Gourdie RG. The Cardiac Gap Junction has Discrete Functions in Electrotonic and Ephaptic Coupling. Anatomical Record (Hoboken, N.J. : 2007). 302: 93-100. PMID 30565418 DOI: 10.1002/Ar.24036  0.478
2019 Lunski M, Smyth J, Vaughn J, Sheng Z, Gourdie R, Purow B, Lamouille S. Abstract 4284: Targeting notch signaling in glioblastoma cancer stem cells through modulation of Connexin43 function Cancer Research. 79: 4284-4284. DOI: 10.1158/1538-7445.Am2019-4284  0.332
2018 Hoagland DT, Santos W, Poelzing S, Gourdie RG. The role of the gap junction perinexus in cardiac conduction: Potential as a novel anti-arrhythmic drug target. Progress in Biophysics and Molecular Biology. PMID 30241906 DOI: 10.1016/J.Pbiomolbio.2018.08.003  0.702
2018 Veeraraghavan R, Hoeker GS, Alvarez-Laviada A, Hoagland D, Wan X, King DR, Sanchez-Alonso J, Chen C, Jourdan J, Isom LL, Deschenes I, Smyth J, Gorelik J, Poelzing S, Gourdie RG. The adhesion function of the sodium channel beta subunit (β1) contributes to cardiac action potential propagation. Elife. 7. PMID 30106376 DOI: 10.7554/Elife.37610  0.671
2018 Montgomery J, Ghatnekar GS, Grek CL, Moyer KE, Gourdie RG. Connexin 43-Based Therapeutics for Dermal Wound Healing. International Journal of Molecular Sciences. 19. PMID 29914066 DOI: 10.3390/Ijms19061778  0.366
2018 Raisch TB, Yanoff MS, Larsen TR, Farooqui MA, King DR, Veeraraghavan R, Gourdie RG, Baker JW, Arnold WS, AlMahameed ST, Poelzing S. Intercalated Disk Extracellular Nanodomain Expansion in Patients With Atrial Fibrillation. Frontiers in Physiology. 9: 398. PMID 29780324 DOI: 10.3389/Fphys.2018.00398  0.663
2018 Lindsey ML, Bolli R, Canty JM, Du XJ, Frangogiannis NG, Frantz S, Gourdie RG, Holmes JW, Jones SP, Kloner RA, Lefer DJ, Liao R, Murphy E, Ping P, Przyklenk K, et al. Guidelines for experimental models of myocardial ischemia and infarction. American Journal of Physiology. Heart and Circulatory Physiology. 314: H812-H838. PMID 29351451 DOI: 10.1152/Ajpheart.00335.2017  0.319
2018 Veeraraghavan R, Hoeker GS, Alvarez-Laviada A, Hoagland D, Wan X, King DR, Sanchez-Alonso J, Chen C, Jourdan J, Isom LL, Deschenes I, Smyth JW, Gorelik J, Poelzing S, Gourdie RG. Author response: The adhesion function of the sodium channel beta subunit (β1) contributes to cardiac action potential propagation Elife. DOI: 10.7554/Elife.37610.025  0.642
2018 Alvarez-Laviada A, Veeraraghavan R, Braga V, Gourdie R, Gorelik J. Dissecting Function and Distribution of Sodium Channels and GAP Junctional Proteins using Super-Resolution Patch-Clamp Biophysical Journal. 114: 202a-203a. DOI: 10.1016/J.Bpj.2017.11.1132  0.322
2017 Rhett JM, Calder BW, Fann SA, Bainbridge H, Gourdie RG, Yost MJ. Mechanism of Action of the Anti-Inflammatory Connexin43-Mimetic Peptide JM2. American Journal of Physiology. Cell Physiology. ajpcell.00229.2016. PMID 28701358 DOI: 10.1152/Ajpcell.00229.2016  0.753
2017 George SA, Calhoun PJ, Gourdie RG, Smyth JW, Poelzing S. TNFα Modulates Cardiac Conduction by Altering Electrical Coupling between Myocytes. Frontiers in Physiology. 8: 334. PMID 28588504 DOI: 10.3389/Fphys.2017.00334  0.66
2017 Lamouille S, Smyth JW, O'Rourke L, Kanabur P, Guo S, Jourdan J, Sheng Z, Gourdie RG. Abstract 4765: Targeting glioblastoma cancer stem cells with a novel Connexin43 mimetic peptide Cancer Research. 77: 4765-4765. DOI: 10.1158/1538-7445.Am2017-4765  0.364
2017 Veeraraghavan R, Hoeker GS, Alvarez Laviada A, Wan X, Deschenes I, Smyth J, Gorelik J, Poelzing S, Gourdie RG. STORM and TEM Identify the Cardiac Ephapse: An Intercalated Disk Nanodomain with Previously Unanticipated Functions in Cardiac Conduction Microscopy and Microanalysis. 23: 1110-1111. DOI: 10.1017/S1431927617006213  0.663
2017 Veeraraghavan R, Hoeker GS, Poelzing S, Gourdie RG. The Sodium Channel Auxiliary Subunit β1 is Structurally Critical for Cardiac Conduction: Evidence from the Single Molecule Scale to the Whole Organ Biophysical Journal. 112: 233a. DOI: 10.1016/J.Bpj.2016.11.1280  0.684
2016 Grek CL, Montgomery J, Sharma M, Ravi A, Rajkumar JS, Moyer KE, Gourdie RG, Ghatnekar GS. A Multicenter, Randomized, Controlled Trial Evaluating a Connexin43-Mimetic Peptide in Cutaneous Scarring. The Journal of Investigative Dermatology. PMID 27856288 DOI: 10.1016/J.Jid.2016.11.006  0.364
2016 Veeraraghavan R, Lin J, Keener JP, Gourdie R, Poelzing S. Potassium channels in the Cx43 gap junction perinexus modulate ephaptic coupling: an experimental and modeling study. Pflugers Archiv : European Journal of Physiology. PMID 27510622 DOI: 10.1007/S00424-016-1861-2  0.659
2016 Veeraraghavan R, Lin J, Keener JP, Gourdie R, Poelzing S. Potassium channels in the Cx43 gap junction perinexus modulate ephaptic coupling: an experimental and modeling study. Pflugers Archiv : European Journal of Physiology. PMID 27510622 DOI: 10.1007/S00424-016-1861-2  0.659
2016 Veeraraghavan R, Lin J, Keener JP, Gourdie R, Poelzing S. Potassium channels in the Cx43 gap junction perinexus modulate ephaptic coupling: an experimental and modeling study. Pflugers Archiv : European Journal of Physiology. PMID 27510622 DOI: 10.1007/S00424-016-1861-2  0.659
2016 Gourdie RG, Dimmeler S, Kohl P. Novel therapeutic strategies targeting fibroblasts and fibrosis in heart disease. Nature Reviews. Drug Discovery. PMID 27339799 DOI: 10.1038/Nrd.2016.89  0.444
2016 Ongstad EL, Gourdie RG. Can Heart Function Lost To Disease Be Regenerated By Therapeutic Targeting Of Cardiac Scar Tissue? Seminars in Cell & Developmental Biology. PMID 27234380 DOI: 10.1016/J.Semcdb.2016.05.020  0.459
2016 Palatinus JA, Gourdie RG. Diabetes Increases Cryoinjury Size with Associated Effects on Cx43 Gap Junction Function and Phosphorylation in the Mouse Heart. Journal of Diabetes Research. 2016: 8789617. PMID 27034963 DOI: 10.1155/2016/8789617  0.755
2016 Palatinus JA, Gourdie RG. Diabetes increases cryoinjury size with associated effects on Cx43 gap junction function and phosphorylation in the mouse heart Journal of Diabetes Research. 2016. DOI: 10.1155/2016/8789617  0.733
2016 Veeraraghavan R, Gourdie RG. STORM-based Quantitative Assessment of Sodium Channel Localization Relative to Junctional Proteins Within the Cardiac Intercalated Disk Microscopy and Microanalysis. 22: 1032-1033. DOI: 10.1017/S1431927616006000  0.401
2016 Veeraraghavan R, Gourdie RG. Novel Storm-Based Quantitative Assessment of Relative Protein Localization Reveals New Role for Sodium Channel β1 Subunit in Cardiac Conduction Biophysical Journal. 110: 110a. DOI: 10.1016/J.Bpj.2015.11.650  0.343
2015 Chen CH, Mayo JN, Gourdie RG, Johnstone SR, Isakson BE, Bearden SE. The Connexin 43/ZO-1 Complex Regulates Cerebral Endothelial F-actin Architecture and Migration. American Journal of Physiology. Cell Physiology. ajpcell.00155.2015. PMID 26289751 DOI: 10.1152/Ajpcell.00155.2015  0.362
2015 Zhang A, Hitomi M, Bar-Shain N, Dalimov Z, Ellis L, Velpula KK, Fraizer GC, Gourdie RG, Lathia JD. Connexin 43 expression is associated with increased malignancy in prostate cancer cell lines and functions to promote migration. Oncotarget. 6: 11640-51. PMID 25960544 DOI: 10.18632/Oncotarget.3449  0.311
2015 George SA, Sciuto KJ, Lin J, Salama ME, Keener JP, Gourdie RG, Poelzing S. Extracellular sodium and potassium levels modulate cardiac conduction in mice heterozygous null for the Connexin43 gene. Pflugers Archiv : European Journal of Physiology. PMID 25771952 DOI: 10.1007/S00424-015-1698-0  0.646
2015 Calder BW, Matthew Rhett J, Bainbridge H, Fann SA, Gourdie RG, Yost MJ. Inhibition of connexin 43 hemichannel-mediated ATP release attenuates early inflammation during the foreign body response. Tissue Engineering. Part A. 21: 1752-62. PMID 25760687 DOI: 10.1089/Ten.Tea.2014.0651  0.32
2015 Grek CL, Prasad GM, Viswanathan V, Armstrong DG, Gourdie RG, Ghatnekar GS. Topical administration of a connexin43-based peptide augments healing of chronic neuropathic diabetic foot ulcers: A multicenter, randomized trial. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 23: 203-12. PMID 25703647 DOI: 10.1111/Wrr.12275  0.305
2015 Veeraraghavan R, Lin J, Hoeker GS, Keener JP, Gourdie RG, Poelzing S. Sodium channels in the Cx43 gap junction perinexus may constitute a cardiac ephapse: an experimental and modeling study. Pflugers Archiv : European Journal of Physiology. PMID 25578859 DOI: 10.1007/S00424-014-1675-Z  0.688
2015 Ghatnekar GS, Grek CL, Armstrong DG, Desai SC, Gourdie RG. The effect of a connexin43-based Peptide on the healing of chronic venous leg ulcers: a multicenter, randomized trial. The Journal of Investigative Dermatology. 135: 289-98. PMID 25072595 DOI: 10.1038/Jid.2014.318  0.347
2015 Chua MJ, El-Dabh A, Sadri S, Gourdie R. REGIONAL VARIATION OF NEONATAL MOUSE HEART IN RESPONSE TO INJURY Journal of the American College of Cardiology. 65: A851. DOI: 10.1016/S0735-1097(15)60851-8  0.347
2015 Veeraraghavan R, Lin J, Keener JP, Poelzing S, Gourdie RG. Superresolution Microscopy Reveals Sodium Channel Localization within Intercalated Disk Microdomains: Implications for Ephaptic Coupling Biophysical Journal. 108: 572a-573a. DOI: 10.1016/J.Bpj.2014.11.3133  0.653
2015 Veeraraghavan R, Lin J, Keener JP, Poelzing S, Gourdie RG. Superresolution Microscopy Reveals Sodium Channel Localization within Intercalated Disk Microdomains: Implications for Ephaptic Coupling Biophysical Journal. 108: 572a-573a. DOI: 10.1016/j.bpj.2014.11.3133  0.579
2015 Ongstad EL, Gourdie RG. Effects of the Connexin43 CT on Gap Junction Sub-Domain Organization and Myocyte-Fibroblast Interactions in the Injury Border Zone Biophysical Journal. 108: 441a-442a. DOI: 10.1016/J.Bpj.2014.11.2412  0.456
2014 Veeraraghavan R, Poelzing S, Gourdie RG. Novel ligands for zipping and unzipping the intercalated disk: today's experimental tools, tomorrow's therapies? Cardiovascular Research. 104: 229-30. PMID 25280893 DOI: 10.1093/Cvr/Cvu216  0.674
2014 Veeraraghavan R, Poelzing S, Gourdie RG. Intercellular electrical communication in the heart: a new, active role for the intercalated disk. Cell Communication & Adhesion. 21: 161-7. PMID 24735129 DOI: 10.3109/15419061.2014.905932  0.68
2014 Veeraraghavan R, Poelzing S, Gourdie RG. Old cogs, new tricks: a scaffolding role for connexin43 and a junctional role for sodium channels? Febs Letters. 588: 1244-8. PMID 24486012 DOI: 10.1016/J.Febslet.2014.01.026  0.692
2014 Moore K, Ghatnekar G, Gourdie RG, Potts JD. Impact of the controlled release of a connexin 43 peptide on corneal wound closure in an STZ model of type I diabetes. Plos One. 9: e86570. PMID 24466155 DOI: 10.1371/Journal.Pone.0086570  0.328
2014 Veeraraghavan R, Gourdie RG, Poelzing S. Mechanisms of cardiac conduction: a history of revisions. American Journal of Physiology. Heart and Circulatory Physiology. 306: H619-27. PMID 24414064 DOI: 10.1152/Ajpheart.00760.2013  0.668
2014 Kohl P, Gourdie RG. Fibroblast-myocyte electrotonic coupling: does it occur in native cardiac tissue? Journal of Molecular and Cellular Cardiology. 70: 37-46. PMID 24412581 DOI: 10.1016/J.Yjmcc.2013.12.024  0.415
2014 Veeraraghavan R, Lin J, Keener J, Poelzing S, Gourdie R. ANISOTROPIC CONDUCTION SLOWING DURING SODIUM CHANNEL BLOCKADE: A ROLE FOR EPHAPTIC COUPLING? Heart Rhythm. 11: 2131. DOI: 10.1016/J.Hrthm.2014.09.018  0.587
2014 Veeraraghavan R, Lin J, Keener J, Poelzing S, Gourdie R. ANISOTROPIC CONDUCTION SLOWING DURING SODIUM CHANNEL BLOCKADE: A ROLE FOR EPHAPTIC COUPLING? Heart Rhythm. 11: 2131. DOI: 10.1016/J.Hrthm.2014.09.018  0.587
2013 Ongstad EL, O'Quinn MP, Ghatnekar GS, Yost MJ, Gourdie RG. A Connexin43 Mimetic Peptide Promotes Regenerative Healing and Improves Mechanical Properties in Skin and Heart. Advances in Wound Care. 2: 55-62. PMID 24527326 DOI: 10.1089/Wound.2011.0341  0.801
2013 Strungs EG, Ongstad EL, O'Quinn MP, Palatinus JA, Jourdan LJ, Gourdie RG. Cryoinjury models of the adult and neonatal mouse heart for studies of scarring and regeneration. Methods in Molecular Biology (Clifton, N.J.). 1037: 343-53. PMID 24029946 DOI: 10.1007/978-1-62703-505-7_20  0.793
2013 Moore K, Bryant ZJ, Ghatnekar G, Singh UP, Gourdie RG, Potts JD. A synthetic connexin 43 mimetic peptide augments corneal wound healing. Experimental Eye Research. 115: 178-88. PMID 23876491 DOI: 10.1016/J.Exer.2013.07.001  0.365
2013 Rhett JM, Veeraraghavan R, Poelzing S, Gourdie RG. The perinexus: sign-post on the path to a new model of cardiac conduction? Trends in Cardiovascular Medicine. 23: 222-8. PMID 23490883 DOI: 10.1016/J.Tcm.2012.12.005  0.82
2013 Moore K, Bryant Z, Vandergriff A, Ghatnekar G, Gourdie R, Potts J. Delivery of a Novel Connexin-43 Mimetic Peptide Enhances Wound Healing Microscopy and Microanalysis. 19: 216-217. DOI: 10.1017/S1431927613003073  0.309
2012 Degen KE, Gourdie RG. Embryonic wound healing: a primer for engineering novel therapies for tissue repair. Birth Defects Research. Part C, Embryo Today : Reviews. 96: 258-70. PMID 23109321 DOI: 10.1002/Bdrc.21019  0.32
2012 Rhett JM, Ongstad EL, Jourdan J, Gourdie RG. Cx43 associates with Na(v)1.5 in the cardiomyocyte perinexus. The Journal of Membrane Biology. 245: 411-22. PMID 22811280 DOI: 10.1007/S00232-012-9465-Z  0.776
2012 Gourdie RG, Myers TA, McFadden A, Li YX, Potts JD. Self-organizing tissue-engineered constructs in collagen hydrogels. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 18: 99-106. PMID 22214557 DOI: 10.1017/S1431927611012372  0.305
2012 Ongstad EL, Gourdie RG. Myocyte-fibroblast electrical coupling: the basis of a stable relationship? Cardiovascular Research. 93: 215-7. PMID 22166713 DOI: 10.1093/Cvr/Cvr338  0.463
2012 Rhett JM, Gourdie RG. The perinexus: a new feature of Cx43 gap junction organization. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 619-23. PMID 21978964 DOI: 10.1016/J.Hrthm.2011.10.003  0.776
2012 Palatinus JA, Rhett JM, Gourdie RG. The connexin43 carboxyl terminus and cardiac gap junction organization. Biochimica Et Biophysica Acta. 1818: 1831-43. PMID 21856279 DOI: 10.1016/J.Bbamem.2011.08.006  0.816
2011 Rémond MC, Iaffaldano G, O'Quinn MP, Mezentseva NV, Garcia V, Harris BS, Gourdie RG, Eisenberg CA, Eisenberg LM. GATA6 reporter gene reveals myocardial phenotypic heterogeneity that is related to variations in gap junction coupling. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1952-64. PMID 21908788 DOI: 10.1152/Ajpheart.00635.2011  0.801
2011 Iravanian S, Sovari AA, Lardin HA, Liu H, Xiao HD, Dolmatova E, Jiao Z, Harris BS, Witham EA, Gourdie RG, Duffy HS, Bernstein KE, Dudley SC. Inhibition of renin-angiotensin system (RAS) reduces ventricular tachycardia risk by altering connexin43. Journal of Molecular Medicine (Berlin, Germany). 89: 677-87. PMID 21553032 DOI: 10.1007/S00109-011-0761-3  0.301
2011 Palatinus JA, Rhett JM, Gourdie RG. Enhanced PKCε mediated phosphorylation of connexin43 at serine 368 by a carboxyl-terminal mimetic peptide is dependent on injury. Channels (Austin, Tex.). 5: 236-40. PMID 21532342 DOI: 10.4161/Chan.5.3.15834  0.795
2011 Rhett JM, Jourdan J, Gourdie RG. Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1. Molecular Biology of the Cell. 22: 1516-28. PMID 21411628 DOI: 10.1091/Mbc.E10-06-0548  0.755
2011 O'Quinn MP, Palatinus JA, Harris BS, Hewett KW, Gourdie RG. A peptide mimetic of the connexin43 carboxyl terminus reduces gap junction remodeling and induced arrhythmia following ventricular injury. Circulation Research. 108: 704-15. PMID 21273554 DOI: 10.1161/Circresaha.110.235747  0.784
2011 Palatinus JA, O'Quinn MP, Barker RJ, Harris BS, Jourdan J, Gourdie RG. ZO-1 determines adherens and gap junction localization at intercalated disks. American Journal of Physiology. Heart and Circulatory Physiology. 300: H583-94. PMID 21131473 DOI: 10.1152/Ajpheart.00999.2010  0.784
2011 Palatinus JA, Rhett JM, Gourdie RG. Enhanced PKCε mediated phosphorylation of connexin43 at serine 368 by a carboxyl-terminal mimetic peptide is dependent on injury Channels. 5.  0.765
2010 Mukherjee R, Colbath GP, Justus CD, Bruce JA, Allen CM, Hewett KW, Saul JP, Gourdie RG, Spinale FG. Spatiotemporal induction of matrix metalloproteinase-9 transcription after discrete myocardial injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3819-28. PMID 20530752 DOI: 10.1096/Fj.10-155531  0.328
2010 Palatinus JA, Rhett JM, Gourdie RG. Translational lessons from scarless healing of cutaneous wounds and regenerative repair of the myocardium. Journal of Molecular and Cellular Cardiology. 48: 550-7. PMID 19560469 DOI: 10.1016/J.Yjmcc.2009.06.013  0.791
2009 Soder BL, Propst JT, Brooks TM, Goodwin RL, Friedman HI, Yost MJ, Gourdie RG. The connexin43 carboxyl-terminal peptide ACT1 modulates the biological response to silicone implants. Plastic and Reconstructive Surgery. 123: 1440-51. PMID 19407614 DOI: 10.1097/Prs.0B013E3181A0741D  0.307
2009 Ghatnekar GS, O'Quinn MP, Jourdan LJ, Gurjarpadhye AA, Draughn RL, Gourdie RG. Connexin43 carboxyl-terminal peptides reduce scar progenitor and promote regenerative healing following skin wounding. Regenerative Medicine. 4: 205-23. PMID 19317641 DOI: 10.2217/17460751.4.2.205  0.785
2008 Gourdie RG, Sedmera D. Letter by Gourdie and Sedmera regarding article, "abnormal conduction and morphology in the atrioventricular node of mice with atrioventricular canal-targeted deletion of Alk3/Bmpr1a receptor". Circulation. 118: e106; author reply e. PMID 18678779 DOI: 10.1161/Circulationaha.108.766345  0.335
2008 Hunter AW, Gourdie RG. The second PDZ domain of zonula occludens-1 is dispensable for targeting to connexin 43 gap junctions. Cell Communication & Adhesion. 15: 55-63. PMID 18649178 DOI: 10.1080/15419060802014370  0.308
2008 Sedmera D, Harris BS, Grant E, Zhang N, Jourdan J, Kurkova D, Gourdie RG. Cardiac expression patterns of endothelin-converting enzyme (ECE): implications for conduction system development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 1746-53. PMID 18489007 DOI: 10.1002/Dvdy.21572  0.404
2008 Rhett JM, Ghatnekar GS, Palatinus JA, O'Quinn M, Yost MJ, Gourdie RG. Novel therapies for scar reduction and regenerative healing of skin wounds. Trends in Biotechnology. 26: 173-80. PMID 18295916 DOI: 10.1016/J.Tibtech.2007.12.007  0.762
2007 Palatinus JA, Gourdie RG. Xin and the art of intercalated disk maintenance. American Journal of Physiology. Heart and Circulatory Physiology. 293: H2626-8. PMID 17873011 DOI: 10.1152/Ajpheart.00954.2007  0.686
2007 Meysen S, Marger L, Hewett KW, Jarry-Guichard T, Agarkova I, Chauvin JP, Perriard JC, Izumo S, Gourdie RG, Mangoni ME, Nargeot J, Gros D, Miquerol L. Nkx2.5 cell-autonomous gene function is required for the postnatal formation of the peripheral ventricular conduction system. Developmental Biology. 303: 740-53. PMID 17250822 DOI: 10.1016/J.Ydbio.2006.12.044  0.369
2007 Gurjarpadhye A, Hewett KW, Justus C, Wen X, Stadt H, Kirby ML, Sedmera D, Gourdie RG. Cardiac neural crest ablation inhibits compaction and electrical function of conduction system bundles. American Journal of Physiology. Heart and Circulatory Physiology. 292: H1291-300. PMID 17172273 DOI: 10.1152/Ajpheart.01017.2006  0.411
2006 Gourdie RG, Ghatnekar GS, O'Quinn M, Rhett MJ, Barker RJ, Zhu C, Jourdan J, Hunter AW. The unstoppable connexin43 carboxyl-terminus: new roles in gap junction organization and wound healing. Annals of the New York Academy of Sciences. 1080: 49-62. PMID 17132774 DOI: 10.1196/Annals.1380.005  0.816
2006 Sedmera D, Wessels A, Trusk TC, Thompson RP, Hewett KW, Gourdie RG. Changes in activation sequence of embryonic chick atria correlate with developing myocardial architecture. American Journal of Physiology. Heart and Circulatory Physiology. 291: H1646-52. PMID 16679393 DOI: 10.1152/Ajpheart.01007.2005  0.328
2006 Lindsey Rose KM, Gourdie RG, Prescott AR, Quinlan RA, Crouch RK, Schey KL. The C terminus of lens aquaporin 0 interacts with the cytoskeletal proteins filensin and CP49. Investigative Ophthalmology & Visual Science. 47: 1562-70. PMID 16565393 DOI: 10.1167/Iovs.05-1313  0.306
2006 Boot MJ, Gittenberger-de Groot AC, Poelmann RE, Gourdie RG. Connexin43 levels are increased in mouse neural crest cells exposed to homocysteine. Birth Defects Research. Part a, Clinical and Molecular Teratology. 76: 133-7. PMID 16397889 DOI: 10.1002/Bdra.20220  0.321
2006 Harris BS, Spruill L, Edmonson AM, Rackley MS, Benson DW, O'Brien TX, Gourdie RG. Differentiation of cardiac Purkinje fibers requires precise spatiotemporal regulation of Nkx2-5 expression. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 38-49. PMID 16245335 DOI: 10.1002/Dvdy.20580  0.344
2005 Hunter AW, Barker RJ, Zhu C, Gourdie RG. Zonula occludens-1 alters connexin43 gap junction size and organization by influencing channel accretion. Molecular Biology of the Cell. 16: 5686-98. PMID 16195341 DOI: 10.1091/Mbc.E05-08-0737  0.696
2005 Zhu C, Barker RJ, Hunter AW, Zhang Y, Jourdan J, Gourdie RG. Quantitative analysis of ZO-1 colocalization with Cx43 gap junction plaques in cultures of rat neonatal cardiomyocytes. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 11: 244-8. PMID 16060977 DOI: 10.1017/S143192760505049X  0.694
2005 Sedmera D, Reckova M, Rosengarten C, Torres MI, Gourdie RG, Thompson RP. Optical mapping of electrical activation in the developing heart. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 11: 209-15. PMID 16060973 DOI: 10.1017/S1431927605050452  0.41
2005 Hewett KW, Norman LW, Sedmera D, Barker RJ, Justus C, Zhang J, Kubalak SW, Gourdie RG. Knockout of the neural and heart expressed gene HF-1b results in apical deficits of ventricular structure and activation. Cardiovascular Research. 67: 548-60. PMID 15907824 DOI: 10.1016/J.Cardiores.2005.04.002  0.684
2005 Harris BS, Gourdie RG, O'Brien TX. Atrioventricular conduction system and transcription factors Nkx2.5 and Msx2. Journal of Cardiovascular Electrophysiology. 16: 86-7. PMID 15673395 DOI: 10.1046/J.1540-8167.2005.04667.X  0.32
2004 Mjaatvedt CH, Klewer S, Wessels A, Gourdie RG. Een geslaagd jubileum! The 10th Weinstein Developmental Cardiovascular Conference in Leiden. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 231: 655-9. PMID 15376316 DOI: 10.1002/Dvdy.20169  0.37
2004 Harris BS, Jay PY, Rackley MS, Izumo S, O'brien TX, Gourdie RG. Transcriptional regulation of cardiac conduction system development: 2004 FASEB cardiac conduction system minimeeting, Washington, DC. The Anatomical Record. Part a, Discoveries in Molecular, Cellular, and Evolutionary Biology. 280: 1036-45. PMID 15368344 DOI: 10.1002/Ar.A.20101  0.385
2004 Jay PY, Harris BS, Buerger A, Rozhitskaya O, Maguire CT, Barbosky LA, McCusty E, Berul CI, O'brien TX, Gourdie RG, Izumo S. Function follows form: cardiac conduction system defects in Nkx2-5 mutation. The Anatomical Record. Part a, Discoveries in Molecular, Cellular, and Evolutionary Biology. 280: 966-72. PMID 15368343 DOI: 10.1002/Ar.A.20102  0.387
2004 Sedmera D, Reckova M, Bigelow MR, Dealmeida A, Stanley CP, Mikawa T, Gourdie RG, Thompson RP. Developmental transitions in electrical activation patterns in chick embryonic heart. The Anatomical Record. Part a, Discoveries in Molecular, Cellular, and Evolutionary Biology. 280: 1001-9. PMID 15368341 DOI: 10.1002/Ar.A.20107  0.41
2004 Jay PY, Harris BS, Maguire CT, Buerger A, Wakimoto H, Tanaka M, Kupershmidt S, Roden DM, Schultheiss TM, O'Brien TX, Gourdie RG, Berul CI, Izumo S. Nkx2-5 mutation causes anatomic hypoplasia of the cardiac conduction system. The Journal of Clinical Investigation. 113: 1130-7. PMID 15085192 DOI: 10.1172/Jci19846  0.392
2004 Hall CE, Hurtado R, Hewett KW, Shulimovich M, Poma CP, Reckova M, Justus C, Pennisi DJ, Tobita K, Sedmera D, Gourdie RG, Mikawa T. Hemodynamic-dependent patterning of endothelin converting enzyme 1 expression and differentiation of impulse-conducting Purkinje fibers in the embryonic heart. Development (Cambridge, England). 131: 581-92. PMID 14711873 DOI: 10.1242/Dev.00947  0.354
2004 Hewett KW, Justus C, Gurjarpadhye A, Sedmera D, Stadt HA, Kirby ML, Gourdie RG. Does neural crest ablation delay or inhibit maturation of the conduction system of the chick embryonic heart? Microscopy and Microanalysis. 10: 178-179. DOI: 10.1017/S1431927604886768  0.34
2004 Zhu C, Barker RJ, Hunter AW, Zhang Y, Jourdan J, Gourdie RG. Quantitative analysis of ZO-1 Co-localization with Cx43 gap junction plaques in cultures of rat neonatal cardiomyocytes Microscopy and Microanalysis. 10: 1392-1393. DOI: 10.1017/S1431927604884745  0.606
2004 Watanabe M, Gourdie RG. Choreography of the heart beat: A special issue of The Anatomical Record on the cardiac pacemaking and conduction system Anatomical Record - Part B New Anatomist. 280: 3. DOI: 10.1002/Ar.B.20033  0.411
2004 Gourdie RG, Watanabe M. Excited by the cardiac pacemaking and conduction system Anatomical Record - Part a Discoveries in Molecular, Cellular, and Evolutionary Biology. 280: 933. DOI: 10.1002/Ar.A.20111  0.373
2003 Hunter AW, Jourdan J, Gourdie RG. Fusion of GFP to the carboxyl terminus of connexin43 increases gap junction size in HeLa cells. Cell Communication & Adhesion. 10: 211-4. PMID 14681018 DOI: 10.1080/Cac.10.4-6.211.214  0.378
2003 Mikawa T, Gourdie RG, Takebayashi-Suzuki K, Kanzawa N, Hyer J, Pennisi DJ, Poma CP, Shulimovich M, Diaz KG, Layliev J, Prasad A. Induction and patterning of the Purkinje fibre network. Novartis Foundation Symposium. 250: 142-53; discussion 1. PMID 12956328 DOI: 10.1007/978-1-59259-878-6_18  0.347
2003 Gourdie RG, Harris BS, Bond J, Edmondson AM, Cheng G, Sedmera D, O'Brien TX, Mikawa T, Thompson RP. His-Purkinje lineages and development. Novartis Foundation Symposium. 250: 110-22; discussion 1. PMID 12956326 DOI: 10.1002/0470868066.Ch7  0.398
2003 Sedmera D, Reckova M, DeAlmeida A, Coppen SR, Kubalak SW, Gourdie RG, Thompson RP. Spatiotemporal pattern of commitment to slowed proliferation in the embryonic mouse heart indicates progressive differentiation of the cardiac conduction system. The Anatomical Record. Part a, Discoveries in Molecular, Cellular, and Evolutionary Biology. 274: 773-7. PMID 12923887 DOI: 10.1002/Ar.A.10085  0.39
2003 Bond J, Sedmera D, Jourdan J, Zhang Y, Eisenberg CA, Eisenberg LM, Gourdie RG. Wnt11 and Wnt7a are up-regulated in association with differentiation of cardiac conduction cells in vitro and in vivo. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 227: 536-43. PMID 12889062 DOI: 10.1002/Dvdy.10333  0.435
2003 Reckova M, Rosengarten C, deAlmeida A, Stanley CP, Wessels A, Gourdie RG, Thompson RP, Sedmera D. Hemodynamics is a key epigenetic factor in development of the cardiac conduction system. Circulation Research. 93: 77-85. PMID 12775585 DOI: 10.1161/01.Res.0000079488.91342.B7  0.419
2003 Gourdie RG, Harris BS, Bond J, Justus C, Hewett KW, O'Brien TX, Thompson RP, Sedmera D. Development of the cardiac pacemaking and conduction system. Birth Defects Research. Part C, Embryo Today : Reviews. 69: 46-57. PMID 12768657 DOI: 10.1002/Bdrc.10008  0.384
2003 Sedmera D, Reckova M, deAlmeida A, Sedmerova M, Biermann M, Volejnik J, Sarre A, Raddatz E, McCarthy RA, Gourdie RG, Thompson RP. Functional and morphological evidence for a ventricular conduction system in zebrafish and Xenopus hearts. American Journal of Physiology. Heart and Circulatory Physiology. 284: H1152-60. PMID 12626327 DOI: 10.1152/Ajpheart.00870.2002  0.398
2002 Pennisi DJ, Rentschler S, Gourdie RG, Fishman GI, Mikawa T. Induction and patterning of the cardiac conduction system. The International Journal of Developmental Biology. 46: 765-75. PMID 12382942 DOI: 10.1387/Ijdb.12382942  0.432
2002 Barker RJ, Gourdie RG. JNK bond regulation: why do mammalian hearts invest in connexin43? Circulation Research. 91: 556-8. PMID 12364381 DOI: 10.1161/01.Res.0000036861.37203.2F  0.704
2002 Barker RJ, Price RL, Gourdie RG. Increased association of ZO-1 with connexin43 during remodeling of cardiac gap junctions. Circulation Research. 90: 317-24. PMID 11861421 DOI: 10.1161/Hh0302.104471  0.729
2002 Cheng G, Wessels A, Gourdie RG, Thompson RP. Spatiotemporal and tissue specific distribution of apoptosis in the developing chick heart. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 223: 119-33. PMID 11803575 DOI: 10.1002/Dvdy.1244  0.323
2001 Barker RJ, Price RL, Gourdie RG. Increased co-localization of connexin43 and ZO-1 in dissociated adult myocytes. Cell Communication & Adhesion. 8: 205-8. PMID 12064589 DOI: 10.3109/15419060109080724  0.711
2001 Thomas PS, Kasahara H, Edmonson AM, Izumo S, Yacoub MH, Barton PJ, Gourdie RG. Elevated expression of Nkx-2.5 in developing myocardial conduction cells. The Anatomical Record. 263: 307-13. PMID 11455540 DOI: 10.1002/Ar.1106  0.399
2000 Nguyên-Trân VT, Kubalak SW, Minamisawa S, Fiset C, Wollert KC, Brown AB, Ruiz-Lozano P, Barrere-Lemaire S, Kondo R, Norman LW, Gourdie RG, Rahme MM, Feld GK, Clark RB, Giles WR, et al. A novel genetic pathway for sudden cardiac death via defects in the transition between ventricular and conduction system cell lineages. Cell. 102: 671-82. PMID 11007485 DOI: 10.1016/S0092-8674(00)00089-1  0.416
2000 Gourdie RG, Cheng G, Thompson RP, Mikawa T. Retroviral cell lineage analysis in the developing chick heart. Methods in Molecular Biology (Clifton, N.J.). 135: 297-304. PMID 10791326 DOI: 10.1385/1-59259-685-1:297  0.355
2000 Litchenberg WH, Norman LW, Holwell AK, Martin KL, Hewett KW, Gourdie RG. The rate and anisotropy of impulse propagation in the postnatal terminal crest are correlated with remodeling of Cx43 gap junction pattern. Cardiovascular Research. 45: 379-87. PMID 10728358 DOI: 10.1016/S0008-6363(99)00363-6  0.432
1999 Cheng G, Litchenberg WH, Cole GJ, Mikawa T, Thompson RP, Gourdie RG. Development of the cardiac conduction system involves recruitment within a multipotent cardiomyogenic lineage. Development (Cambridge, England). 126: 5041-9. PMID 10529421  0.319
1999 Gourdie RG, Kubalak S, Mikawa T. Conducting the embryonic heart: orchestrating development of specialized cardiac tissues. Trends in Cardiovascular Medicine. 9: 18-26. PMID 10189963 DOI: 10.1016/S1050-1738(98)00035-8  0.433
1999 Coppen SR, Severs NJ, Gourdie RG. Connexin45 (alpha 6) expression delineates an extended conduction system in the embryonic and mature rodent heart. Developmental Genetics. 24: 82-90. PMID 10079513 DOI: 10.1002/(Sici)1520-6408(1999)24:1/2<82::Aid-Dvg9>3.0.Co;2-1  0.329
1999 Gourdie RG, Lo CW. Chapter 26: Cx43 (α1) Gap Junctions in Cardiac Development and Disease Current Topics in Membranes and Transport. 49: 581-602. DOI: 10.1016/S0070-2161(08)61030-8  0.405
1998 Becker DL, Cook JE, Davies CS, Evans WH, Gourdie RG. Expression of major gap junction connexin types in the working myocardium of eight chordates. Cell Biology International. 22: 527-43. PMID 10452821 DOI: 10.1006/Cbir.1998.0295  0.326
1998 Gittenberger-de Groot AC, Vrancken Peeters MP, Mentink MM, Gourdie RG, Poelmann RE. Epicardium-derived cells contribute a novel population to the myocardial wall and the atrioventricular cushions. Circulation Research. 82: 1043-52. PMID 9622157 DOI: 10.1161/01.Res.82.10.1043  0.363
1998 Gourdie RG, Wei Y, Kim D, Klatt SC, Mikawa T. Endothelin-induced conversion of embryonic heart muscle cells into impulse-conducting Purkinje fibers. Proceedings of the National Academy of Sciences of the United States of America. 95: 6815-8. PMID 9618495 DOI: 10.1073/Pnas.95.12.6815  0.412
1998 Kilarski WM, Dupont E, Coppen S, Yeh HI, Vozzi C, Gourdie RG, Rezapour M, Ulmsten U, Roomans GM, Severs NJ. Identification of two further gap-junctional proteins, connexin40 and connexin45, in human myometrial smooth muscle cells at term. European Journal of Cell Biology. 75: 1-8. PMID 9523149 DOI: 10.1016/S0171-9335(98)80040-X  0.349
1997 Angst BD, Khan LU, Severs NJ, Whitely K, Rothery S, Thompson RP, Magee AI, Gourdie RG. Dissociated spatial patterning of gap junctions and cell adhesion junctions during postnatal differentiation of ventricular myocardium. Circulation Research. 80: 88-94. PMID 8978327 DOI: 10.1161/01.Res.80.1.88  0.411
1996 Sepp R, Severs NJ, Gourdie RG. Altered patterns of cardiac intercellular junction distribution in hypertrophic cardiomyopathy. Heart (British Cardiac Society). 76: 412-7. PMID 8944586 DOI: 10.1136/Hrt.76.5.412  0.449
1995 Hall JE, Gourdie RG. Spatial organization of cardiac gap junctions can affect access resistance. Microscopy Research and Technique. 31: 446-51. PMID 8534905 DOI: 10.1002/Jemt.1070310513  0.445
1995 Gourdie RG. A map of the heart: gap junctions, connexin diversity and retroviral studies of conduction myocyte lineage. Clinical Science (London, England : 1979). 88: 257-62. PMID 7736693 DOI: 10.1042/Cs0880257  0.464
1995 McCabe CF, Gourdie RG, Thompson RP, Cole GJ. Developmentally regulated neural protein EAP-300 is expressed by myocardium and cardiac neural crest during chick embryogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 203: 51-60. PMID 7647374 DOI: 10.1002/Aja.1002030106  0.393
1993 Severs NJ, Gourdie RG, Harfst E, Peters NS, Green CR. Intercellular junctions and the application of microscopical techniques: the cardiac gap junction as a case model. Journal of Microscopy. 169: 299-328. PMID 8478912 DOI: 10.1111/J.1365-2818.1993.Tb03308.X  0.478
1993 Gourdie RG, Green CR, Severs NJ, Anderson RH, Thompson RP. Evidence for a distinct gap-junctional phenotype in ventricular conduction tissues of the developing and mature avian heart. Circulation Research. 72: 278-89. PMID 8380357 DOI: 10.1161/01.Res.72.2.278  0.412
1993 Gourdie RG, Severs NJ, Green CR, Rothery S, Germroth P, Thompson RP. The spatial distribution and relative abundance of gap-junctional connexin40 and connexin43 correlate to functional properties of components of the cardiac atrioventricular conduction system. Journal of Cell Science. 105: 985-91. PMID 8227219  0.337
1993 Jones S, Gray C, Sakamaki H, Arora M, Boyde A, Gourdie R, Green C. The incidence and size of gap junctions between the bone cells in rat calvaria Anatomy and Embryology. 187. DOI: 10.1007/Bf00185892  0.323
1992 Gourdie RG, Green CR, Severs NJ, Thompson RP. Immunolabelling patterns of gap junction connexins in the developing and mature rat heart. Anatomy and Embryology. 185: 363-78. PMID 1319120 DOI: 10.1007/Bf00188548  0.429
1990 Severs NJ, Harfst E, Gourdie R, Green C. Antibodies to cardiac gap-junctional protein: Biochemical and morphological applications Journal of Molecular and Cellular Cardiology. 22: S38. DOI: 10.1016/0022-2828(90)91641-J  0.366
1988 Green CR, Harfst E, Gourdie RG, Severs NJ. Analysis of the rat liver gap junction protein: clarification of anomalies in its molecular size. Proceedings of the Royal Society of London. Series B, Biological Sciences. 233: 165-74. PMID 2898146 DOI: 10.1098/Rspb.1988.0016  0.313
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