Loren Dean Williams, PhD - Publications

Affiliations: 
School of Chemistry & Biochemistry Georgia Institute of Technology, Atlanta, GA 
Area:
DNA, intercalators, crystallography, RNA, ribosome, evolution
Website:
http://ww2.chemistry.gatech.edu/~lw26/bBiography/biography.html

132 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Edri R, Fisher S, Menor-Salvan C, Williams LD, Frenkel-Pinter M. Assembly-driven protection from hydrolysis as key selective force during chemical evolution. Febs Letters. PMID 37884438 DOI: 10.1002/1873-3468.14766  0.692
2023 Guth-Metzler R, Mohamed AM, Cowan ET, Henning A, Ito C, Frenkel-Pinter M, Wartell RM, Glass JB, Williams LD. Goldilocks and RNA: where Mg2+ concentration is just right. Nucleic Acids Research. PMID 36987860 DOI: 10.1093/nar/gkad124  0.722
2023 Kim H, Moore CM, Mestre-Fos S, Hanna DA, Williams LD, Reddi AR, Torres MP. Depletion Assisted Hemin Affinity (DAsHA) Proteomics Reveals an Expanded Landscape of Heme Binding Proteins in the Human Proteome. Metallomics : Integrated Biometal Science. PMID 36669767 DOI: 10.1093/mtomcs/mfad004  0.778
2022 C M, Frenkel-Pinter M, Smith KH, Rivera-Santana VF, Sargon AB, Jacobson KC, Guzman-Martinez A, Williams LD, Leman LJ, Liotta CL, Grover MA, Hud NV. Water-Based Dynamic Depsipeptide Chemistry: Building Block Recycling and Oligomer Distribution Control Using Hydration-Dehydration Cycles. Jacs Au. 2: 1395-1404. PMID 35783166 DOI: 10.1021/jacsau.2c00087  0.777
2022 Frenkel-Pinter M, Bouza M, Fernández FM, Leman LJ, Williams LD, Hud NV, Guzman-Martinez A. Thioesters provide a plausible prebiotic path to proto-peptides. Nature Communications. 13: 2569. PMID 35562173 DOI: 10.1038/s41467-022-30191-0  0.768
2022 Frenkel-Pinter M, Petrov AS, Matange K, Travisano M, Glass JB, Williams LD. Adaptation and Exaptation: From Small Molecules to Feathers. Journal of Molecular Evolution. PMID 35246710 DOI: 10.1007/s00239-022-10049-1  0.727
2022 Frenkel-Pinter M, Jacobson KC, Eskew-Martin J, Forsythe JG, Grover MA, Williams LD, Hud NV. Differential Oligomerization of Alpha versus Beta Amino Acids and Hydroxy Acids in Abiotic Proto-Peptide Synthesis Reactions. Life (Basel, Switzerland). 12. PMID 35207553 DOI: 10.3390/life12020265  0.763
2021 Frenkel-Pinter M, Sargon AB, Glass JB, Hud NV, Williams LD. Transition metals enhance prebiotic depsipeptide oligomerization reactions involving histidine. Rsc Advances. 11: 3534-3538. PMID 35424306 DOI: 10.1039/d0ra07965k  0.76
2021 Penev PI, McCann HM, Meade CD, Alvarez-Carreño C, Maddala A, Bernier CR, Chivukula VL, Ahmad M, Gulen B, Sharma A, Williams LD, Petrov AS. ProteoVision: web server for advanced visualization of ribosomal proteins. Nucleic Acids Research. PMID 33999189 DOI: 10.1093/nar/gkab351  0.78
2021 Frenkel-Pinter M, Rajaei V, Glass JB, Hud NV, Williams LD. Water and Life: The Medium is the Message. Journal of Molecular Evolution. PMID 33427903 DOI: 10.1007/s00239-020-09978-6  0.759
2020 Mascuch SJ, Fakhretaha-Aval S, Bowman JC, Ma MTH, Thomas G, Bommarius B, Ito C, Zhao L, Newnam GP, Matange KR, Thapa HR, Barlow B, Donegan RK, Nguyen NA, Saccuzzo EG, ... ... Williams LD, et al. A blueprint for academic labs to produce SARS-CoV-2 RT-qPCR test kits. The Journal of Biological Chemistry. PMID 32883809 DOI: 10.1074/Jbc.Ra120.015434  0.759
2020 Mestre-Fos S, Ito C, Moore CM, Reddi AR, Williams LD. Human Ribosomal G-Quadruplexes Regulate Heme Bioavailability. The Journal of Biological Chemistry. PMID 32817343 DOI: 10.1074/Jbc.Ra120.014332  0.767
2020 Penev PI, Fakhretaha-Aval S, Patel VJ, Cannone JJ, Gutell RR, Petrov AS, Williams LD, Glass JB. Supersized ribosomal RNA expansion segments in Asgard archaea. Genome Biology and Evolution. PMID 32785681 DOI: 10.1093/Gbe/Evaa170  0.475
2020 Mascuch SJ, Fakhretaha-Aval S, Bowman JC, Ma MTH, Thomas G, Bommarius B, Ito C, Zhao L, Newnam GP, Matange KR, Thapa HR, Barlow B, Donegan RK, Nguyen NA, Saccuzzo EG, ... ... Williams LD, et al. Buzz about RT-qPCR: An RT-qPCR formulation for SARS-CoV-2 detection using reagents produced at Georgia Institute of Technology. Medrxiv : the Preprint Server For Health Sciences. PMID 32766604 DOI: 10.1101/2020.07.29.20163949  0.76
2020 Guth-Metzler R, Bray MS, Frenkel-Pinter M, Suttapitugsakul S, Montllor-Albalate C, Bowman JC, Wu R, Reddi AR, Okafor CD, Glass JB, Williams LD. Cutting in-line with iron: ribosomal function and non-oxidative RNA cleavage. Nucleic Acids Research. PMID 32663277 DOI: 10.1093/Nar/Gkaa586  0.775
2020 Frenkel-Pinter M, Haynes JW, Mohyeldin AM, C M, Sargon AB, Petrov AS, Krishnamurthy R, Hud NV, Williams LD, Leman LJ. Mutually stabilizing interactions between proto-peptides and RNA. Nature Communications. 11: 3137. PMID 32561731 DOI: 10.1038/S41467-020-16891-5  0.798
2020 Bowman JC, Petrov AS, Frenkel-Pinter M, Penev PI, Williams LD. Root of the Tree: The Significance, Evolution, and Origins of the Ribosome. Chemical Reviews. PMID 32374986 DOI: 10.1021/Acs.Chemrev.9B00742  0.755
2019 Mestre-Fos S, Penev PI, Richards JC, Dean WL, Gray RD, Chaires JB, Williams LD. Profusion of G-quadruplexes on both subunits of metazoan ribosomes. Plos One. 14: e0226177. PMID 31834895 DOI: 10.1371/Journal.Pone.0226177  0.791
2019 Frenkel-Pinter M, Haynes JW, C M, Petrov AS, Burcar BT, Krishnamurthy R, Hud NV, Leman LJ, Williams LD. Selective incorporation of proteinaceous over nonproteinaceous cationic amino acids in model prebiotic oligomerization reactions. Proceedings of the National Academy of Sciences of the United States of America. PMID 31358633 DOI: 10.1073/Pnas.1904849116  0.781
2019 Mestre-Fos S, Penev PI, Suttapitugsakul S, Ito C, Petrov AS, Wartell RM, Wu R, Williams LD. G-Quadruplexes in Human Ribosomal RNA. Journal of Molecular Biology. PMID 30885721 DOI: 10.1016/J.Jmb.2019.03.010  0.788
2018 Fang PY, Bowman JC, Gómez Ramos LM, Hsiao C, Williams LD. RNA: packaged and protected by VLPs. Rsc Advances. 8: 21399-21406. PMID 35539947 DOI: 10.1039/c8ra02084a  0.558
2018 Runnels CM, Lanier KA, Williams JK, Bowman JC, Petrov AS, Hud NV, Williams LD. Folding, Assembly, and Persistence: The Essential Nature and Origins of Biopolymers. Journal of Molecular Evolution. PMID 30456440 DOI: 10.1007/S00239-018-9876-2  0.774
2018 Bray MS, Lenz TK, Haynes JW, Bowman JC, Petrov AS, Reddi AR, Hud NV, Williams LD, Glass JB. Multiple prebiotic metals mediate translation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30413624 DOI: 10.1073/Pnas.1803636115  0.776
2018 Kovacs NA, Penev PI, Venapally A, Petrov AS, Williams LD. Circular Permutation Obscures Universality of a Ribosomal Protein. Journal of Molecular Evolution. PMID 30306205 DOI: 10.1007/S00239-018-9869-1  0.342
2018 Bernier CR, Petrov AS, Kovacs NA, Penev P, Williams LD. Translation: The Universal Structural Core of Life. Molecular Biology and Evolution. PMID 29788252 DOI: 10.1093/Molbev/Msy101  0.36
2018 Fang P, Bowman JC, Gómez Ramos L, Hsiao C, Williams LD. RNA: packaged and protected by VLPs Rsc Advances. 8: 21399-21406. DOI: 10.1039/C8Ra02084A  0.541
2017 Gómez Ramos LM, Degtyareva NN, Kovacs NA, Holguin SY, Jiang L, Petrov AS, Biesiada M, Hu MY, Purzycka KJ, Arya DP, Williams LD. Eukaryotic Ribosomal Expansion Segments as Antimicrobial Targets. Biochemistry. PMID 28895721 DOI: 10.1021/Acs.Biochem.7B00703  0.323
2017 Lanier KA, Petrov AS, Williams LD. The Central Symbiosis of Molecular Biology: Molecules in Mutualism. Journal of Molecular Evolution. PMID 28785970 DOI: 10.1007/S00239-017-9804-X  0.805
2017 Lanier KA, Roy P, Schneider DM, Williams LD. Ancestral Interactions of Ribosomal RNA and Ribosomal Proteins. Biophysical Journal. PMID 28506527 DOI: 10.1016/J.Bpj.2017.04.007  0.809
2017 Okafor CD, Lanier KA, Petrov AS, Athavale SS, Bowman JC, Hud NV, Williams LD. Iron mediates catalysis of nucleic acid processing enzymes: support for Fe(II) as a cofactor before the great oxidation event. Nucleic Acids Research. PMID 28334877 DOI: 10.1093/Nar/Gkx171  0.781
2017 Lanier KA, Williams LD. The Origin of Life: Models and Data. Journal of Molecular Evolution. PMID 28243688 DOI: 10.1007/S00239-017-9783-Y  0.787
2017 Lenz TK, Norris AM, Hud NV, Williams LD. Protein-free ribosomal RNA folds to a near-native state in the presence of Mg2+ Rsc Advances. 7: 54674-54681. DOI: 10.1039/C7Ra08696B  0.735
2016 Fang PY, Gómez Ramos LM, Holguin SY, Hsiao C, Bowman JC, Yang HW, Williams LD. Functional RNAs: combined assembly and packaging in VLPs. Nucleic Acids Research. PMID 27903913 DOI: 10.1093/Nar/Gkw1154  0.594
2016 Ramos LM, Smeekens JM, Kovacs NA, Bowman JC, Wartell RM, Wu R, Williams LD. Yeast rRNA Expansion Segments: Folding and Function. Journal of Molecular Biology. PMID 27521697 DOI: 10.1016/J.Jmb.2016.08.008  0.481
2016 Lanier KA, Athavale SS, Petrov AS, Wartell RM, Williams LD. Imprint of Ancient Evolution on rRNA Folding. Biochemistry. PMID 27428664 DOI: 10.1021/Acs.Biochem.6B00168  0.795
2016 Gulen B, Petrov AS, Okafor CD, Vander Wood D, O'Neill EB, Hud NV, Williams LD. Ribosomal small subunit domains radiate from a central core. Scientific Reports. 6: 20885. PMID 26876483 DOI: 10.1038/Srep20885  0.772
2016 Komeda S, Qu Y, Mangrum JB, Hegmans A, Williams LD, Farrell NP. The phosphate clamp as recognition motif in platinum-DNA interactions Inorganica Chimica Acta. DOI: 10.1016/J.Ica.2016.04.052  0.437
2015 Petrov AS, Gulen B, Norris AM, Kovacs NA, Bernier CR, Lanier KA, Fox GE, Harvey SC, Wartell RM, Hud NV, Williams LD. History of the ribosome and the origin of translation. Proceedings of the National Academy of Sciences of the United States of America. PMID 26621738 DOI: 10.1073/Pnas.1509761112  0.778
2015 Petrov AS, Williams LD. The ancient heart of the ribosomal large subunit: a response to Caetano-Anolles. Journal of Molecular Evolution. 80: 166-70. PMID 25877522 DOI: 10.1007/S00239-015-9678-8  0.465
2015 Bowman JC, Hud NV, Williams LD. The ribosome challenge to the RNA world. Journal of Molecular Evolution. 80: 143-61. PMID 25739364 DOI: 10.1007/S00239-015-9669-9  0.742
2015 Fox GE, Paci M, Tran Q, Petrov AS, Williams LD. Ribosome dynamics and the evolutionary history of ribosomes Proceedings of Spie - the International Society For Optical Engineering. 9606. DOI: 10.1117/12.2187098  0.324
2014 Harris LA, Williams LD, Koudelka GB. Specific minor groove solvation is a crucial determinant of DNA binding site recognition. Nucleic Acids Research. 42: 14053-9. PMID 25429976 DOI: 10.1093/Nar/Gku1259  0.359
2014 Bernier CR, Petrov AS, Waterbury CC, Jett J, Li F, Freil LE, Xiong X, Wang L, Migliozzi BL, Hershkovits E, Xue Y, Hsiao C, Bowman JC, Harvey SC, Grover MA, ... ... Williams LD, et al. RiboVision suite for visualization and analysis of ribosomes. Faraday Discussions. 169: 195-207. PMID 25340471 DOI: 10.1039/C3Fd00126A  0.559
2014 Petrov AS, Bernier CR, Hsiao C, Norris AM, Kovacs NA, Waterbury CC, Stepanov VG, Harvey SC, Fox GE, Wartell RM, Hud NV, Williams LD. Evolution of the ribosome at atomic resolution. Proceedings of the National Academy of Sciences of the United States of America. 111: 10251-6. PMID 24982194 DOI: 10.1073/Pnas.1407205111  0.766
2014 Petrov AS, Bernier CR, Gulen B, Waterbury CC, Hershkovits E, Hsiao C, Harvey SC, Hud NV, Fox GE, Wartell RM, Williams LD. Secondary structures of rRNAs from all three domains of life. Plos One. 9: e88222. PMID 24505437 DOI: 10.1371/Journal.Pone.0088222  0.79
2014 Ma Z, Chen W, Johnson MC, Schmidt-Krey I, Williams L, Schuster GB. Modular-DNA programmed molecular construction of "Fixed" of 2D and 3D-Au nanoparticle arrays Chemistry of Materials. 26: 5499-5505. DOI: 10.1021/Cm501459A  0.306
2013 Jones BL, VanLoozen J, Kim MH, Miles SJ, Dunham CM, Williams LD, Snell TW. Stress granules form in Brachionus manjavacas (Rotifera) in response to a variety of stressors. Comparative Biochemistry and Physiology. Part a, Molecular & Integrative Physiology. 166: 375-84. PMID 23856158 DOI: 10.1016/J.Cbpa.2013.07.009  0.572
2013 Petrov AS, Bernier CR, Hershkovits E, Xue Y, Waterbury CC, Hsiao C, Stepanov VG, Gaucher EA, Grover MA, Harvey SC, Hud NV, Wartell RM, Fox GE, Williams LD. Secondary structure and domain architecture of the 23S and 5S rRNAs. Nucleic Acids Research. 41: 7522-35. PMID 23771137 DOI: 10.1093/Nar/Gkt513  0.752
2013 Hsiao C, Chou IC, Okafor CD, Bowman JC, O'Neill EB, Athavale SS, Petrov AS, Hud NV, Wartell RM, Harvey SC, Williams LD. RNA with iron(II) as a cofactor catalyses electron transfer. Nature Chemistry. 5: 525-8. PMID 23695635 DOI: 10.1038/Nchem.1649  0.794
2013 Hud NV, Cafferty BJ, Krishnamurthy R, Williams LD. The origin of RNA and "my grandfather's axe". Chemistry & Biology. 20: 466-74. PMID 23601635 DOI: 10.1016/J.Chembiol.2013.03.012  0.708
2013 Hsiao C, Lenz TK, Peters JK, Fang PY, Schneider DM, Anderson EJ, Preeprem T, Bowman JC, O'Neill EB, Lie L, Athavale SS, Gossett JJ, Trippe C, Murray J, Petrov AS, ... ... Williams LD, et al. Molecular paleontology: a biochemical model of the ancestral ribosome. Nucleic Acids Research. 41: 3373-85. PMID 23355613 DOI: 10.1093/Nar/Gkt023  0.775
2013 Athavale SS, Gossett JJ, Bowman JC, Hud NV, Williams LD, Harvey SC. In vitro secondary structure of the genomic RNA of satellite tobacco mosaic virus. Plos One. 8: e54384. PMID 23349871 DOI: 10.1371/Journal.Pone.0054384  0.722
2013 Harris LA, Watkins D, Williams LD, Koudelka GB. Indirect readout of DNA sequence by p22 repressor: roles of DNA and protein functional groups in modulating DNA conformation. Journal of Molecular Biology. 425: 133-43. PMID 23085222 DOI: 10.1016/J.Jmb.2012.10.008  0.369
2012 Bowman JC, Azizi B, Lenz TK, Roy P, Williams LD. Preparation of long templates for RNA in vitro transcription by recursive PCR. Methods in Molecular Biology (Clifton, N.J.). 941: 19-41. PMID 23065551 DOI: 10.1007/978-1-62703-113-4_3  0.385
2012 Petrov AS, Bernier CR, Hsiao C, Okafor CD, Tannenbaum E, Stern J, Gaucher E, Schneider D, Hud NV, Harvey SC, Williams LD. RNA-magnesium-protein interactions in large ribosomal subunit. The Journal of Physical Chemistry. B. 116: 8113-20. PMID 22712611 DOI: 10.1021/Jp304723W  0.802
2012 Athavale SS, Petrov AS, Hsiao C, Watkins D, Prickett CD, Gossett JJ, Lie L, Bowman JC, O'Neill E, Bernier CR, Hud NV, Wartell RM, Harvey SC, Williams LD. RNA folding and catalysis mediated by iron (II). Plos One. 7: e38024. PMID 22701543 DOI: 10.1371/Journal.Pone.0038024  0.761
2012 Bowman JC, Lenz TK, Hud NV, Williams LD. Cations in charge: magnesium ions in RNA folding and catalysis. Current Opinion in Structural Biology. 22: 262-72. PMID 22595008 DOI: 10.1016/J.Sbi.2012.04.006  0.697
2012 Engelhart AE, Cafferty BJ, Okafor CD, Chen MC, Williams LD, Lynn DG, Hud NV. Nonenzymatic ligation of DNA with a reversible step and a final linkage that can be used in PCR. Chembiochem : a European Journal of Chemical Biology. 13: 1121-4. PMID 22556064 DOI: 10.1002/Cbic.201200167  0.789
2012 Athavale SS, Gossett JJ, Hsiao C, Bowman JC, O'Neill E, Hershkovitz E, Preeprem T, Hud NV, Wartell RM, Harvey SC, Williams LD. Domain III of the T. thermophilus 23S rRNA folds independently to a near-native state. Rna (New York, N.Y.). 18: 752-8. PMID 22334759 DOI: 10.1261/Rna.030692.111  0.744
2012 Maehigashi T, Hsiao C, Woods KK, Moulaei T, Hud NV, Williams LD. B-DNA structure is intrinsically polymorphic: even at the level of base pair positions. Nucleic Acids Research. 40: 3714-22. PMID 22180536 DOI: 10.1093/Nar/Gkr1168  0.787
2011 Buckley R, Enekwa CD, Williams LD, Hud NV. Molecular recognition of Watson-Crick-like purine-purine base pairs. Chembiochem : a European Journal of Chemical Biology. 12: 2155-8. PMID 21805554 DOI: 10.1002/Cbic.201100375  0.713
2011 Petrov AS, Bowman JC, Harvey SC, Williams LD. Bidentate RNA-magnesium clamps: on the origin of the special role of magnesium in RNA folding. Rna (New York, N.Y.). 17: 291-7. PMID 21173199 DOI: 10.1261/Rna.2390311  0.385
2011 Komeda S, Moulaei T, Chikuma M, Odani A, Kipping R, Farrell NP, Williams LD. The phosphate clamp: a small and independent motif for nucleic acid backbone recognition. Nucleic Acids Research. 39: 325-36. PMID 20736180 DOI: 10.1093/Nar/Gkq723  0.782
2011 Watkins D, Harris LA, Koudelka GB, Williams LD. Protein: Feeling the groove of DNA Acs Symposium Series. 1082: 133-145. DOI: 10.1021/Bk-2011-1082.Ch008  0.327
2010 Mohan S, Hsiao C, Bowman JC, Wartell R, Williams LD. RNA tetraloop folding reveals tension between backbone restraints and molecular interactions. Journal of the American Chemical Society. 132: 12679-89. PMID 20726568 DOI: 10.1021/Ja104387K  0.7
2010 Watkins D, Mohan S, Koudelka GB, Williams LD. Sequence recognition of DNA by protein-induced conformational transitions. Journal of Molecular Biology. 396: 1145-64. PMID 20053356 DOI: 10.1016/J.Jmb.2009.12.050  0.587
2010 Watkins D, Moulaei T, Komeda S, Williams LD. Application of anomalous diffraction methods to the study of DNA and DNA-complexes. Methods in Molecular Biology (Clifton, N.J.). 613: 133-52. PMID 19997882 DOI: 10.1007/978-1-60327-418-0_9  0.787
2009 Mohan S, Hsiao C, VanDeusen H, Gallagher R, Krohn E, Kalahar B, Wartell RM, Williams LD. Mechanism of RNA double helix-propagation at atomic resolution. The Journal of Physical Chemistry. B. 113: 2614-23. PMID 19708202 DOI: 10.1021/Jp8039884  0.698
2009 Hsiao C, Mohan S, Kalahar BK, Williams LD. Peeling the onion: ribosomes are ancient molecular fossils. Molecular Biology and Evolution. 26: 2415-25. PMID 19628620 DOI: 10.1093/Molbev/Msp163  0.71
2009 Hsiao C, Williams LD. A recurrent magnesium-binding motif provides a framework for the ribosomal peptidyl transferase center. Nucleic Acids Research. 37: 3134-42. PMID 19279186 DOI: 10.1093/Nar/Gkp119  0.547
2009 Apostolico A, Ciriello G, Guerra C, Heitsch CE, Hsiao C, Williams LD. Finding 3D motifs in ribosomal RNA structures. Nucleic Acids Research. 37: e29. PMID 19158187 DOI: 10.1093/Nar/Gkn1044  0.581
2008 Watkins D, Hsiao C, Woods KK, Koudelka GB, Williams LD. P22 c2 repressor-operator complex: mechanisms of direct and indirect readout. Biochemistry. 47: 2325-38. PMID 18237194 DOI: 10.1021/Bi701826F  0.741
2008 Richardson JS, Schneider B, Murray LW, Kapral GJ, Immormino RM, Headd JJ, Richardson DC, Ham D, Hershkovits E, Williams LD, Keating KS, Pyle AM, Micallef D, Westbrook J, Berman HM, et al. RNA backbone: consensus all-angle conformers and modular string nomenclature (an RNA Ontology Consortium contribution). Rna (New York, N.Y.). 14: 465-81. PMID 18192612 DOI: 10.1261/Rna.657708  0.378
2006 Komeda S, Moulaei T, Woods KK, Chikuma M, Farrell NP, Williams LD. A third mode of DNA binding: Phosphate clamps by a polynuclear platinum complex. Journal of the American Chemical Society. 128: 16092-103. PMID 17165762 DOI: 10.1021/Ja062851Y  0.791
2006 Gold B, Marky LM, Stone MP, Williams LD. A review of the role of the sequence-dependent electrostatic landscape in DNA alkylation patterns. Chemical Research in Toxicology. 19: 1402-14. PMID 17112226 DOI: 10.1021/Tx060127N  0.34
2006 Hershkovitz E, Sapiro G, Tannenbaum A, Williams LD. Statistical analysis of RNA backbone. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 3: 33-46. PMID 17048391 DOI: 10.1109/Tcbb.2006.13  0.345
2006 Hsiao C, Mohan S, Hershkovitz E, Tannenbaum A, Williams LD. Single nucleotide RNA choreography. Nucleic Acids Research. 34: 1481-91. PMID 16531589 DOI: 10.1093/Nar/Gkj500  0.691
2005 Moulaei T, Maehigashi T, Lountos GT, Komeda S, Watkins D, Stone MP, Marky LA, Li JS, Gold B, Williams LD. Structure of B-DNA with cations tethered in the major groove. Biochemistry. 44: 7458-68. PMID 15895989 DOI: 10.1021/Bi050128Z  0.797
2004 Woods KK, Maehigashi T, Howerton SB, Sines CC, Tannenbaum S, Williams LD. High-resolution structure of an extended A-tract: [d(CGCAAATTTGCG)]2. Journal of the American Chemical Society. 126: 15330-1. PMID 15563130 DOI: 10.1021/Ja045207X  0.79
2003 Hershkovitz E, Tannenbaum E, Howerton SB, Sheth A, Tannenbaum A, Williams LD. Automated identification of RNA conformational motifs: theory and application to the HM LSU 23S rRNA. Nucleic Acids Research. 31: 6249-57. PMID 14576313 DOI: 10.1093/Nar/Gkg835  0.786
2003 Razskazovskiy Y, Debije MG, Howerton SB, Williams LD, Bernhard WA. Strand breaks in X-irradiated crystalline DNA: alternating CG oligomers. Radiation Research. 160: 334-9. PMID 12926992 DOI: 10.1667/Rr3051  0.786
2003 Howerton SB, Nagpal A, Williams LD. Surprising roles of electrostatic interactions in DNA-ligand complexes. Biopolymers. 69: 87-99. PMID 12717724 DOI: 10.1002/Bip.10319  0.787
2003 Woods KK, Lan T, McLaughlin LW, Williams LD. The role of minor groove functional groups in DNA hydration. Nucleic Acids Research. 31: 1536-40. PMID 12595562 DOI: 10.1093/Nar/Gkg240  0.659
2003 Reynisson J, Schuster GB, Howerton SB, Williams LD, Barnett RN, Cleveland CL, Landman U, Harrit N, Chaires JB. Intercalation of trioxatriangulenium ion in DNA: binding, electron transfer, x-ray crystallography, and electronic structure. Journal of the American Chemical Society. 125: 2072-83. PMID 12590535 DOI: 10.1021/Ja0211196  0.788
2002 Hamelberg D, Williams LD, Wilson WD. Effect of a neutralized phosphate backbone on the minor groove of B-DNA: molecular dynamics simulation studies. Nucleic Acids Research. 30: 3615-23. PMID 12177304 DOI: 10.1093/Nar/Gkf472  0.369
2001 Howerton SB, Sines CC, VanDerveer D, Williams LD. Locating monovalent cations in the grooves of B-DNA. Biochemistry. 40: 10023-31. PMID 11513580 DOI: 10.1021/Bi010391+  0.777
2001 Peek ME, Williams LD. X-ray crystallography of DNA-drug complexes. Methods in Enzymology. 340: 282-90. PMID 11494854 DOI: 10.1016/S0076-6879(01)40427-7  0.318
2000 Williams LD, Maher LJ. Electrostatic mechanisms of DNA deformation. Annual Review of Biophysics and Biomolecular Structure. 29: 497-521. PMID 10940257 DOI: 10.1146/Annurev.Biophys.29.1.497  0.358
2000 Shui X, Peek ME, Lipscomb LA, Wilkinson AP, Williams LD, Gao M, Ogata C, Roques BP, Garbay-Jaureguiberry C, Wilkinson AP, Williams LD. Effects of cationic charge on three-dimensional structures of intercalative complexes: structure of a bis-intercalated DNA complex solved by MAD phasing. Current Medicinal Chemistry. 7: 59-71. PMID 10637357 DOI: 10.2174/0929867003375470  0.343
2000 Woods KK, McFail-Isom L, Sines CC, Howerton SB, Stephens RK, Williams LD. Monovalent cations sequester within the A-tract minor groove of [d(CGCGAATTCGCG)]2 [4] Journal of the American Chemical Society. 122: 1546-1547. DOI: 10.2210/Pdb1Dou/Pdb  0.76
2000 Sines CC, McFail-Isom L, Howerton SB, VanDerveer D, Williams LD. Cations mediate B-DNA conformational heterogeneity Journal of the American Chemical Society. 122: 11048-11056. DOI: 10.1021/Ja002244P  0.787
1999 McFail-Isom L, Sines CC, Williams LD. DNA structure: cations in charge? Current Opinion in Structural Biology. 9: 298-304. PMID 10361089 DOI: 10.1016/S0959-440X(99)80040-2  0.348
1998 McFail-Isom L, Shui X, Williams LD. Divalent cations stabilize unstacked conformations of DNA and RNA by interacting with base pi systems. Biochemistry. 37: 17105-11. PMID 9860822 DOI: 10.1021/Bi982201+  0.427
1998 Presnell SR, Patil GS, Mura C, Jude KM, Conley JM, Bertrand JA, Kam CM, Powers JC, Williams LD. Oxyanion-mediated inhibition of serine proteases. Biochemistry. 37: 17068-81. PMID 9836602 DOI: 10.1021/Bi981636U  0.744
1998 Shui X, Sines CC, McFail-Isom L, VanDerveer D, Williams LD. Structure of the potassium form of CGCGAATTCGCG: DNA deformation by electrostatic collapse around inorganic cations. Biochemistry. 37: 16877-87. PMID 9836580 DOI: 10.1021/Bi982063O  0.381
1998 Milano MT, Hu GG, Williams LD, Bernhard WA. Migration of electrons and holes in crystalline d(CGATCG)-anthracycline complexes X-irradiated at 4 K. Radiation Research. 150: 101-14. PMID 9650607 DOI: 10.2307/3579650  0.324
1998 Shui X, McFail-Isom L, Hu GG, Williams LD. The B-DNA dodecamer at high resolution reveals a spine of water on sodium. Biochemistry. 37: 8341-55. PMID 9622486 DOI: 10.1021/Bi973073C  0.39
1998 Gasper SM, Armitage B, Shui X, Hu GG, Changjun Y, Schuster GB, Williams LD. Three-dimensional structure and reactivity of a photochemical cleavage agent bound to DNA Journal of the American Chemical Society. 120: 12402-12409. DOI: 10.2210/Pdb386D/Pdb  0.385
1997 Hu GG, Shui X, Leng F, Priebe W, Chaires JB, Williams LD. Structure of a DNA-bisdaunomycin complex. Biochemistry. 36: 5940-6. PMID 9166763 DOI: 10.1021/Bi9705218  0.361
1997 Breslin DT, Coury JE, Anderson JR, McFail-Isom L, Kan Y, Williams LD, Bottomley LA, Schuster GB. Anthraquinone photonuclease structure determines its mode of binding to DNA and the cleavage chemistry observed [5] Journal of the American Chemical Society. 119: 5043-5044. DOI: 10.1021/Ja963607H  0.355
1997 Coury JE, Anderson JR, McFail-Isom L, Williams LD, Bottomley LA. Scanning force microscopy of small ligand-nucleic acid complexes: Tris(o-phenanthroline)ruthenium(II) as a test for a new assay Journal of the American Chemical Society. 119: 3792-3796. DOI: 10.1021/Ja9623774  0.341
1996 Lipscomb LA, Zhou FX, Presnell SR, Woo RJ, Peek ME, Plaskon RR, Williams LD. Structure of DNA-porphyrin complex. Biochemistry. 35: 2818-23. PMID 8608116 DOI: 10.1021/Bi952443Z  0.377
1996 Bertrand JA, Oleksyszyn J, Kam CM, Boduszek B, Presnell S, Plaskon RR, Suddath FL, Powers JC, Williams LD. Inhibition of trypsin and thrombin by amino(4-amidinophenyl)methanephosphonate diphenyl ester derivatives: X-ray structures and molecular models. Biochemistry. 35: 3147-55. PMID 8605148 DOI: 10.1021/Bi9520996  0.308
1996 Williams LD, Lipscomb LA, Zhou FX, Presnell SR, Woo RJ, Peek ME. Structure of a DNA-porphyrin complex Acta Crystallographica Section A. 52. DOI: 10.1107/S0108767396093361  0.341
1996 Gao Q, Sood A, Shaw BR, Williams LD. 2′-Deoxycytidine-N3-cyanoborane Acta Crystallographica Section C: Crystal Structure Communications. 52: 1823-1825.  0.429
1995 Lipscomb LA, Peek ME, Morningstar ML, Verghis SM, Miller EM, Rich A, Essigmann JM, Williams LD. X-ray structure of a DNA decamer containing 7,8-dihydro-8-oxoguanine. Proceedings of the National Academy of Sciences of the United States of America. 92: 719-23. PMID 7846041 DOI: 10.1073/Pnas.92.3.719  0.501
1995 Peek ME, Lipscomb LA, Haseltine J, Gao Q, Roques BP, Garbay-Jaureguiberry C, Williams LD. Asymmetry and dynamics in bis-intercalated DNA. Bioorganic & Medicinal Chemistry. 3: 693-9. PMID 7582947 DOI: 10.1016/0968-0896(95)00064-N  0.378
1995 Coury JE, McFail-lsom L, Presnell S, Williams LD, Bottomley LA. Scanning probe visualization of electrostatically immobilized intercalating drug—nucleic acid complexes Journal of Vacuum Science and Technology a: Vacuum, Surfaces and Films. 13: 1746-1751. DOI: 10.1116/1.579763  0.367
1994 Peek ME, Lipscomb LA, Bertrand JA, Gao Q, Roques BP, Garbay-Jaureguiberry C, Williams LD. DNA distortion in bis-intercalated complexes. Biochemistry. 33: 3794-800. PMID 8142381 DOI: 10.1021/Bi00179A002  0.365
1994 Lipscomb LA, Peek ME, Zhou FX, Bertrand JA, VanDerveer D, Williams LD. Water ring structure at DNA interfaces: hydration and dynamics of DNA-anthracycline complexes. Biochemistry. 33: 3649-59. PMID 8142363 DOI: 10.1021/Bi00178A023  0.346
1994 Bancroft D, Williams LD, Rich A, Egli M. The low-temperature crystal structure of the pure-spermine form of Z-DNA reveals binding of a spermine molecule in the minor groove. Biochemistry. 33: 1073-86. PMID 8110738 DOI: 10.2210/Pdb131D/Pdb  0.649
1992 Williams LD, Gao Q. DNA-ditercalinium interactions: implications for recognition of damaged DNA. Biochemistry. 31: 4315-24. PMID 1567878 DOI: 10.1021/Bi00132A024  0.358
1992 MacPhail RA, Williams LD, Jones DA, Shaw BR. Variable temperature infrared spectroscopy of cytosine-guanine base pairs: tautomerism versus polarization. Journal of Biomolecular Structure & Dynamics. 9: 881-98. PMID 1524704 DOI: 10.1080/07391102.1992.10507964  0.562
1991 Gao Q, Williams LD, Egli M, Rabinovich D, Chen SL, Quigley GJ, Rich A. Drug-induced DNA repair: X-ray structure of a DNA-ditercalinium complex. Proceedings of the National Academy of Sciences of the United States of America. 88: 2422-6. PMID 2006181 DOI: 10.1073/Pnas.88.6.2422  0.626
1991 Egli M, Williams LD, Frederick CA, Rich A. DNA-nogalamycin interactions. Biochemistry. 30: 1364-72. PMID 1991116 DOI: 10.1021/Bi00219A029  0.657
1991 Feuerstein BG, Williams LD, Basu HS, Marton LJ. Implications and concepts of polyamine-nucleic acid interactions. Journal of Cellular Biochemistry. 46: 37-47. PMID 1874798 DOI: 10.1002/Jcb.240460107  0.373
1991 Egli M, Williams LD, Gao Q, Rich A. Structure of the pure-spermine form of Z-DNA (magnesium free) at 1-A resolution. Biochemistry. 30: 11388-402. PMID 1742278 DOI: 10.1021/Bi00112A005  0.658
1990 Frederick CA, Williams LD, Ughetto G, van der Marel GA, van Boom JH, Rich A, Wang AH. Structural comparison of anticancer drug-DNA complexes: adriamycin and daunomycin. Biochemistry. 29: 2538-49. PMID 2334681 DOI: 10.1021/Bi00462A016  0.517
1990 Williams LD, Egli M, Qi G, Bash P, van der Marel GA, van Boom JH, Rich A, Frederick CA. Structure of nogalamycin bound to a DNA hexamer. Proceedings of the National Academy of Sciences of the United States of America. 87: 2225-9. PMID 2315315 DOI: 10.1073/Pnas.87.6.2225  0.649
1990 Williams LD, Frederick CA, Ughetto G, Rich A. Ternary interactions of spermine with DNA: 4'-epiadriamycin and other DNA: anthracycline complexes. Nucleic Acids Research. 18: 5533-41. PMID 2216725 DOI: 10.1093/Nar/18.18.5533  0.528
1990 McCarthy JG, Williams LD, Rich A. Chemical reactivity of potassium permanganate and diethyl pyrocarbonate with B DNA: specific reactivity with short A-tracts. Biochemistry. 29: 6071-81. PMID 2166574 DOI: 10.1021/Bi00477A027  0.53
1990 Egli M, Gessner RV, Williams LD, Quigley GJ, van der Marel GA, van Boom JH, Rich A, Frederick CA. Atomic-resolution structure of the cellulose synthase regulator cyclic diguanylic acid. Proceedings of the National Academy of Sciences of the United States of America. 87: 3235-9. PMID 2158107 DOI: 10.1073/Pnas.87.8.3235  0.625
1990 Williams LD, Egli M, Ughetto G, van der Marel GA, van Boom JH, Quigley GJ, Wang AH, Rich A, Frederick CA. Structure of 11-deoxydaunomycin bound to DNA containing a phosphorothioate. Journal of Molecular Biology. 215: 313-20. PMID 2152325 DOI: 10.1016/S0022-2836(05)80349-3  0.647
1990 Williams LD, Williams NG, Shaw BR. In a model cytosine:guanine base pair, one amino group rotates and the other does not Journal of the American Chemical Society. 112: 829-833. DOI: 10.1021/Ja00158A050  0.543
1990 Williams LD, Williams NG, Shaw BR. In a model C:G base pair, one amino group rotates and the other does not Journal of the American Chemical Society. 112: 829-833.  0.484
1989 Williams NG, Williams LD, Shaw BR. Dimers, trimers, and tetramers of cytosine with guanine Journal of the American Chemical Society. 111: 7205-7209. DOI: 10.1021/Ja00200A046  0.554
1988 Williams LD, Thivierge J, Goldberg IH. Specific binding of o-phenanthroline at a DNA structural lesion. Nucleic Acids Research. 16: 11607-15. PMID 2850540 DOI: 10.1093/Nar/16.24.11607  0.304
1988 Williams LD, Goldberg IH. Selective strand scission by intercalating drugs at DNA bulges. Biochemistry. 27: 3004-11. PMID 2456781 DOI: 10.1021/Bi00408A051  0.342
1987 Williams LD, Chawla B, Shaw BR. The hydrogen bonding of cytosine with guanine: calorimetric and 1H-nmr analysis of the molecular interactions of nucleic acid bases. Biopolymers. 26: 591-603. PMID 3567328 DOI: 10.1002/Bip.360260411  0.552
1987 Williams LD, Shaw BR. Protonated base pairs explain the ambiguous pairing properties of O6-methylguanine. Proceedings of the National Academy of Sciences of the United States of America. 84: 1779-83. PMID 3470757 DOI: 10.1073/Pnas.84.7.1779  0.561
1983 AARTSMA TJ, GOUTERMAN M, JOCHUM C, KWIRAM AL, PEPICH BV, WILLIAMS LD. ChemInform Abstract: PORPHYRINS. 43. TRIPLET SUBLEVEL EMISSION OF PLATINUM TETRABENZOPORPHYRIN BY SPECTROTHERMAL PRINCIPAL COMPONENT DECOMPOSITION Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198307284  0.423
1982 Aartsma TJ, Gouterman M, Jochum C, Kwiram AL, Pepich BV, Williams LD. Porphyrins. 43. Triplet sublevel emission of platinum tetrabenzoporphyrin by spectrothermal principal component decomposition Journal of the American Chemical Society. 104: 6278-6283. DOI: 10.1021/Ja00387A021  0.482
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