Monte S. Willis - Publications

Affiliations: 
2005-2018 Pathology University of North Carolina, Chapel Hill, Chapel Hill, NC 
 2018- Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Pathology, Biochemistry, Molecular Biology

130 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tian S, Nakamura J, Hiller S, Simington S, Holley DW, Mota R, Willis MS, Bultman SJ, Luft JC, DeSimone JM, Jia Z, Maeda N, Yi X. New insights into immunomodulation via overexpressing lipoic acid synthase as a therapeutic potential to reduce atherosclerosis. Vascular Pharmacology. 106777. PMID 32750408 DOI: 10.1016/J.Vph.2020.106777  0.314
2020 Rajalingam S, Kambrath AV, Vidal R, Willis MS. Deletion of the Microtubule‐associated protein tau (Mapt−/−) results in diastolic heart failure and altered skeletal muscle function in vivo The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02885  0.337
2019 Suryadevara V, Willis MS. Walk the Line: The Role of Ubiquitin in Regulating Transcription in Myocytes. Physiology (Bethesda, Md.). 34: 327-340. PMID 31389777 DOI: 10.1152/Physiol.00055.2018  0.322
2019 Oakley RH, Cruz-Topete D, He B, Foley JF, Myers PH, Xu X, Gomez-Sanchez CE, Chambon P, Willis MS, Cidlowski JA. Cardiomyocyte glucocorticoid and mineralocorticoid receptors directly and antagonistically regulate heart disease in mice. Science Signaling. 12. PMID 30992401 DOI: 10.1126/Scisignal.Aau9685  0.368
2019 Willis MS, Parry TL, Brown DI, Mota RI, Huang W, Beak JY, Sola M, Zhou C, Hicks ST, Caughey MC, D'Agostino RB, Jordan J, Hundley WG, Jensen BC. Doxorubicin Exposure Causes Subacute Cardiac Atrophy Dependent on the Striated Muscle-Specific Ubiquitin Ligase MuRF1. Circulation. Heart Failure. 12: e005234. PMID 30871347 DOI: 10.1161/Circheartfailure.118.005234  0.38
2019 Ling TY, Yi F, Lu T, Wang XL, Sun X, Willis MS, Wu LQ, Shen WK, Adelman JP, Lee HC. F-box protein-32 down-regulates small-conductance calcium-activated potassium channel 2 in diabetic mouse atria. The Journal of Biological Chemistry. PMID 30635400 DOI: 10.1074/Jbc.Ra118.003837  0.326
2018 Oakley RH, Campen MJ, Paffett ML, Chen X, Wang Z, Parry TL, Hillhouse C, Cidlowski JA, Willis MS. Muscle-specific regulation of right ventricular transcriptional responses to chronic hypoxia-induced hypertrophy by the muscle ring finger-1 (MuRF1) ubiquitin ligase in mice. Bmc Medical Genetics. 19: 175. PMID 30241514 DOI: 10.1186/S12881-018-0670-1  0.338
2018 Ravi S, Parry TL, Willis MS, Lockyer P, Patterson C, Bain JR, Stevens RD, Ilkayeva OR, Newgard CB, Schisler JC. Adverse Effects of Fenofibrate in Mice Deficient in the Protein Quality Control Regulator, CHIP. Journal of Cardiovascular Development and Disease. 5. PMID 30111698 DOI: 10.3390/Jcdd5030043  0.401
2018 Mota R, Parry TL, Yates C, Qiang Z, Eaton SC, Mwiza JM, Tulasi D, Schisler JC, Patterson C, Zaglia T, Sandri M, Willis MS. Increasing Cardiomyocyte Atrogin-1 Reduces Aging-Associated Fibrosis and Regulates Remodeling In Vivo. The American Journal of Pathology. PMID 29758183 DOI: 10.1016/J.Ajpath.2018.04.007  0.351
2018 Pascual F, Schisler JC, Grevengoed TJ, Willis MS, Coleman RA. Modeling the Transition From Decompensated to Pathological Hypertrophy. Journal of the American Heart Association. 7. PMID 29622588 DOI: 10.1161/Jaha.117.008293  0.319
2018 Ranek MJ, Stachowski MJ, Kirk JA, Willis MS. The role of heat shock proteins and co-chaperones in heart failure. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 29203715 DOI: 10.1098/Rstb.2016.0530  0.361
2018 Parry T, Altamirano F, Hill J, Gillette T, Willis M. The muscle-specific MuRF1 ubiquitin ligase transcriptionally regulates cardiomyocyte autophagy in a FOXO1/3-dependent manner and protects against cardiac inflammation in vivo Journal of Molecular and Cellular Cardiology. 124: 114. DOI: 10.1016/J.Yjmcc.2018.07.092  0.372
2017 Abdullah M, Berthiaume JM, Willis MS. Tumor necrosis factor receptor-associated factor 6 as a nuclear factor kappa B-modulating therapeutic target in cardiovascular diseases: at the heart of it all. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 29175266 DOI: 10.1016/J.Trsl.2017.10.012  0.364
2017 Mota R, Rodríguez JE, Bonetto A, O'Connell TM, Asher SA, Parry TL, Lockyer P, McCudden CR, Couch ME, Willis MS. Post-translationally modified muscle-specific ubiquitin ligases as circulating biomarkers in experimental cancer cachexia. American Journal of Cancer Research. 7: 1948-1958. PMID 28979816  0.604
2017 Jensen BC, Parry TL, Huang W, Beak JY, Ilaiwy A, Bain JR, Newgard CB, Muehlbauer MJ, Patterson C, Johnson GL, Willis MS. Effects of the Kinase Inhibitor Sorafenib on Heart, Muscle, Liver, and Plasma Metabolism In Vivo using Non-Targeted Metabolomics Analysis. British Journal of Pharmacology. PMID 28977680 DOI: 10.1111/Bph.14062  0.338
2017 Meng Q, Bhandary B, Osinska H, James J, Xu N, Shay-Winkler K, Gulick J, Willis MS, Lander C, Robbins J. MMI-0100 Inhibits Cardiac Fibrosis in a Mouse Model Overexpressing Cardiac Myosin Binding Protein C. Journal of the American Heart Association. 6. PMID 28871043 DOI: 10.1161/Jaha.117.006590  0.359
2017 Starnes JW, Parry TL, O'Neal SK, Bain JR, Muehlbauer MJ, Honcoop A, Ilaiwy A, Christopher PM, Patterson C, Willis MS. Exercise-Induced Alterations in Skeletal Muscle, Heart, Liver, and Serum Metabolome Identified by Non-Targeted Metabolomics Analysis. Metabolites. 7. PMID 28786928 DOI: 10.3390/Metabo7030040  0.341
2017 Brown DI, Parry TL, Willis MS. Ubiquitin Ligases and Posttranslational Regulation of Energy in the Heart: The Hand that Feeds. Comprehensive Physiology. 7: 841-862. PMID 28640445 DOI: 10.1002/Cphy.C160024  0.353
2017 Jensen BC, Parry TL, Huang W, Ilaiwy A, Bain JR, Muehlbauer MJ, O'Neal SK, Patterson C, Johnson GL, Willis MS. Non-Targeted Metabolomics Analysis of the Effects of Tyrosine Kinase Inhibitors Sunitinib and Erlotinib on Heart, Muscle, Liver and Serum Metabolism In Vivo. Metabolites. 7. PMID 28640223 DOI: 10.3390/Metabo7030031  0.363
2017 Willis MS, Holley DW, Wang Z, Chen X, Quintana M, Jensen BC, Tannu M, Parker J, Jeyaraj D, Jain MK, Wolfram JA, Lee HG, Bultman SJ. BRG1 and BRM function antagonistically with c-MYC in adult cardiomyocytes to regulate conduction and contractility. Journal of Molecular and Cellular Cardiology. PMID 28232072 DOI: 10.1016/J.Yjmcc.2017.02.003  0.326
2017 Parry T, Mota R, Willis M. The muscle-specific ubiquitin ligase Atrogin-1 (MAFbx) inhibits age-associated cardiac fibrosis by enhancing MMP-9 levels in vivo Journal of Molecular and Cellular Cardiology. 112: 166-167. DOI: 10.1016/J.Yjmcc.2017.07.107  0.319
2016 Brown DI, Cooley BC, Quintana MT, Lander C, Willis MS. Nebulized Delivery of the MAPKAP Kinase 2 Peptide Inhibitor MMI-0100 Protects Against Ischemia-Induced Systolic Dysfunction. International Journal of Peptide Research and Therapeutics. 22: 317-324. PMID 28989333 DOI: 10.1007/S10989-015-9507-3  0.336
2016 Ilaiwy A, Liu M, Parry TL, Bain JR, Newgard CB, Schisler JC, Muehlbauer MJ, Despa F, Willis MS. Human amylin proteotoxicity impairs protein biosynthesis, and alters major cellular signaling pathways in the heart, brain and liver of humanized diabetic rat model in vivo. Metabolomics : Official Journal of the Metabolomic Society. 12. PMID 28775675 DOI: 10.1007/S11306-016-1022-9  0.322
2016 Willis MS, Ilaiwy A, Montgomery MD, Simpson PC, Jensen BC. The alpha-1A adrenergic receptor agonist A61603 reduces cardiac polyunsaturated fatty acid and endocannabinoid metabolites associated with inflammation in vivo. Metabolomics : Official Journal of the Metabolomic Society. 12. PMID 28533737 DOI: 10.1007/S11306-016-1097-3  0.309
2016 Files DC, Ilaiwy A, Parry TL, Gibbs KW, Liu C, Bain JR, Delbono O, Muehlbauer MJ, Willis MS. Lung injury-induced skeletal muscle wasting in aged mice is linked to alterations in long chain fatty acid metabolism. Metabolomics : Official Journal of the Metabolomic Society. 12. PMID 28217037 DOI: 10.1007/S11306-016-1079-5  0.32
2016 Ilaiwy A, Quintana MT, Bain JR, Muehlbauer MJ, Brown DI, Stansfield WE, Willis MS. Cessation of biomechanical stretch model of C2C12 cells models myocyte atrophy and anaplerotic changes in metabolism using non-targeted metabolomics analysis. The International Journal of Biochemistry & Cell Biology. PMID 27515590 DOI: 10.1016/J.Biocel.2016.08.012  0.324
2016 Parry TL, Willis MS. Cardiac ubiquitin ligases: Their role in cardiac metabolism, autophagy, cardioprotection and therapeutic potential. Biochimica Et Biophysica Acta. PMID 27421947 DOI: 10.1016/J.Bbadis.2016.07.002  0.377
2016 Quintana MT, Parry TL, He J, Yates CC, Sidorova TN, Murray KT, Bain JR, Newgard CB, Muehlbauer MJ, Eaton SC, Hishiya A, Takayama S, Willis MS. Cardiomyocyte-Specific Human Bcl2-Associated Anthanogene 3 P209L Expression Induces Mitochondrial Fragmentation, Bcl2-Associated Anthanogene 3 Haploinsufficiency, and Activates p38 Signaling. The American Journal of Pathology. PMID 27321750 DOI: 10.1016/J.Ajpath.2016.03.017  0.412
2016 Cruz-Topete D, Myers PH, Foley JF, Willis MS, Cidlowski JA. Corticosteroids are Essential for Maintaining Cardiovascular Function in Male Mice. Endocrinology. en20151604. PMID 27219275 DOI: 10.1210/En.2015-1604  0.367
2016 Bultman SJ, Holley DW, G de Ridder G, Pizzo SV, Sidorova TN, Murray KT, Jensen BC, Wang Z, Bevilacqua A, Chen X, Quintana MT, Tannu M, Rosson GB, Pandya K, Willis MS. BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 25: 258-269. PMID 27039070 DOI: 10.1016/J.Carpath.2016.02.004  0.33
2016 Wadosky KM, Berthiaume J, Tang W, Zungu M, Portman M, Gerdes M, Willis MS. MuRF1 mono-ubiquitinates TRα to inhibit T3 induced cardiac hypertrophy in vivo. Journal of Molecular Endocrinology. PMID 26862156 DOI: 10.1530/Jme-15-0283  0.35
2016 Parry TL, Desai G, Schisler JC, Li L, Quintana MT, Stanley N, Lockyer P, Patterson C, Willis MS. Fenofibrate unexpectedly induces cardiac hypertrophy in mice lacking MuRF1. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 25: 127-40. PMID 26764147 DOI: 10.1016/J.Carpath.2015.09.008  0.391
2015 Banerjee R, He J, Spaniel C, Quintana MT, Wang Z, Bain J, Newgard CB, Muehlbauer MJ, Willis MS. Non-targeted metabolomics analysis of cardiac Muscle Ring Finger-1 (MuRF1), MuRF2, and MuRF3 in vivo reveals novel and redundant metabolic changes. Metabolomics : Official Journal of the Metabolomic Society. 11: 312-322. PMID 28325996 DOI: 10.1007/S11306-014-0695-1  0.382
2015 Parry TL, Melehani JH, Ranek MJ, Willis MS. Functional Amyloid Signaling via the Inflammasome, Necrosome, and Signalosome: New Therapeutic Targets in Heart Failure. Frontiers in Cardiovascular Medicine. 2: 25. PMID 26664897 DOI: 10.3389/Fcvm.2015.00025  0.38
2015 Banerjee R, Bultman SJ, Holley D, Hillhouse C, Bain JR, Newgard CB, Muehlbauer MJ, Willis MS. Non-targeted metabolomics of Brg1/Brm double-mutant cardiomyocytes reveals a novel role for SWI/SNF complexes in metabolic homeostasis. Metabolomics : Official Journal of the Metabolomic Society. 11: 1287-1301. PMID 26392817 DOI: 10.1007/S11306-015-0786-7  0.37
2015 He J, Quintana MT, Sullivan J, L Parry T, J Grevengoed T, Schisler JC, Hill JA, Yates CC, Mapanga RF, Essop MF, Stansfield WE, Bain JR, Newgard CB, Muehlbauer MJ, Han Y, ... ... Willis MS, et al. MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet. Cardiovascular Diabetology. 14: 97. PMID 26242235 DOI: 10.1186/S12933-015-0252-X  0.375
2015 Quintana MT, He J, Sullivan J, Grevengoed T, Schisler J, Han Y, Hill JA, Yates CC, Stansfield WE, Mapanga RF, Essop MF, Muehlbauer MJ, Newgard CB, Bain JR, Willis MS. Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet. Bmc Endocrine Disorders. 15: 36. PMID 26215257 DOI: 10.1186/S12902-015-0028-Z  0.358
2015 Rodríguez JE, Liao JY, He J, Schisler JC, Newgard CB, Drujan D, Glass DL, Frederick CB, Yoder BC, Lalush DS, Patterson C, Willis MS. The Ubiquitin Ligase MuRF1 Regulates PPARα Activity in the Heart by Enhancing Nuclear Export via Monoubiquitination. Molecular and Cellular Endocrinology. PMID 26116825 DOI: 10.1016/J.Mce.2015.06.008  0.665
2015 Schisler JC, Grevengoed TJ, Pascual F, Cooper DE, Ellis JM, Paul DS, Willis MS, Patterson C, Jia W, Coleman RA. Cardiac energy dependence on glucose increases metabolites related to glutathione and activates metabolic genes controlled by mechanistic target of rapamycin. Journal of the American Heart Association. 4. PMID 25713290 DOI: 10.1161/Jaha.114.001136  0.313
2015 Xie L, Pi X, Wang Z, He J, Willis MS, Patterson C. Depletion of PHD3 protects heart from ischemia/reperfusion injury by inhibiting cardiomyocyte apoptosis. Journal of Molecular and Cellular Cardiology. 80: 156-65. PMID 25633836 DOI: 10.1016/J.Yjmcc.2015.01.007  0.338
2015 McCormick ME, Collins C, Makarewich CA, Chen Z, Rojas M, Willis MS, Houser SR, Tzima E. Platelet endothelial cell adhesion molecule-1 mediates endothelial-cardiomyocyte communication and regulates cardiac function. Journal of the American Heart Association. 4: e001210. PMID 25600142 DOI: 10.1161/Jaha.114.001210  0.378
2015 Mattox TA, Young ME, Rubel CE, Spaniel C, Rodríguez JE, Grevengoed TJ, Gautel M, Xu Z, Anderson EJ, Willis MS. Erratum to: MuRF1 activity is present in cardiac mitochondria and regulates reactive oxygen species production in vivo. Journal of Bioenergetics and Biomembranes. 47: 281. PMID 25515723 DOI: 10.1007/S10863-014-9597-1  0.622
2015 Skrzynia C, Berg JS, Willis MS, Jensen BC. Genetics and heart failure: a concise guide for the clinician. Current Cardiology Reviews. 11: 10-7. PMID 24251456 DOI: 10.2174/1573403X09666131117170446  0.306
2015 Quintana MT, Willis MS, Stansfield WE. Bag3+ P209L Transgene Provides a Cardiac-Specific Murine Model of Nonischemic Cardiomyopathy Journal of the American College of Surgeons. 221: S23. DOI: 10.1016/J.Jamcollsurg.2015.07.040  0.331
2014 Xu L, Yates CC, Lockyer P, Xie L, Bevilacqua A, He J, Lander C, Patterson C, Willis M. MMI-0100 inhibits cardiac fibrosis in myocardial infarction by direct actions on cardiomyocytes and fibroblasts via MK2 inhibition. Journal of Molecular and Cellular Cardiology. 77: 86-101. PMID 25257914 DOI: 10.1016/J.Yjmcc.2014.09.011  0.367
2014 Campen MJ, Paffett ML, Colombo ES, Lucas SN, Anderson T, Nysus M, Norenberg JP, Gershman B, Hesterman J, Hoppin J, Willis M. Muscle RING finger-1 promotes a maladaptive phenotype in chronic hypoxia-induced right ventricular remodeling. Plos One. 9: e97084. PMID 24811453 DOI: 10.1371/Journal.Pone.0097084  0.313
2014 Mattox TA, Young ME, Rubel CE, Spaniel C, Rodríguez JE, Grevengoed TJ, Gautel M, Xu Z, Anderson EJ, Willis MS. MuRF1 activity is present in cardiac mitochondria and regulates reactive oxygen species production in vivo. Journal of Bioenergetics and Biomembranes. 46: 173-87. PMID 24733503 DOI: 10.1007/S10863-014-9549-9  0.376
2014 Paul DS, Grevengoed TJ, Pascual F, Ellis JM, Willis MS, Coleman RA. Deficiency of cardiac Acyl-CoA synthetase-1 induces diastolic dysfunction, but pathologic hypertrophy is reversed by rapamycin. Biochimica Et Biophysica Acta. 1841: 880-7. PMID 24631848 DOI: 10.1016/J.Bbalip.2014.03.001  0.377
2014 Wadosky KM, Rodríguez JE, Hite RL, Min JN, Walton BL, Willis MS. Muscle RING finger-1 attenuates IGF-I-dependent cardiomyocyte hypertrophy by inhibiting JNK signaling. American Journal of Physiology. Endocrinology and Metabolism. 306: E723-39. PMID 24425758 DOI: 10.1152/Ajpendo.00326.2013  0.341
2014 Duryee MJ, Willis MS, Schaffert CS, Reidelberger RD, Dusad A, Anderson DR, Klassen LW, Thiele GM. Precision-cut liver slices from diet-induced obese rats exposed to ethanol are susceptible to oxidative stress and increased fatty acid synthesis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G208-17. PMID 24284960 DOI: 10.1152/Ajpgi.00124.2013  0.516
2014 Willis MS, Bevilacqua A, Pulinilkunnil T, Kienesberger P, Tannu M, Patterson C. The role of ubiquitin ligases in cardiac disease. Journal of Molecular and Cellular Cardiology. 71: 43-53. PMID 24262338 DOI: 10.1016/J.Yjmcc.2013.11.008  0.402
2014 Bevilacqua A, Willis MS, Bultman SJ. SWI/SNF chromatin-remodeling complexes in cardiovascular development and disease. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 23: 85-91. PMID 24183004 DOI: 10.1016/J.Carpath.2013.09.003  0.376
2014 Willis MS, Wadosky KM, Rodríguez JE, Schisler JC, Lockyer P, Hilliard EG, Glass DJ, Patterson C. Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1-mediated gene expression in vivo. Cell Biochemistry and Function. 32: 39-50. PMID 23512667 DOI: 10.1002/Cbf.2969  0.357
2014 Schisler J, Grevengoed T, Ellis J, Paul D, Willis M, Patterson C, Coleman R. P663Cardiac energy dependence on glucose increases metabolites related to glutathione and activates metabolic genes controlled by mTOR Cardiovascular Research. 103: S121.2-S121. DOI: 10.1093/Cvr/Cvu098.88  0.335
2014 Quintana MT, He J, Stansfield WE, Willis MS. Cardiac Peroxisome Proliferator-activated Receptor-γ (PPAR-γ) and PPAR-β Activity Is Up-Regulated in the Absence of Muscle RING Finger-2 (MuRF2) and MuRF3, Respectively, and Exaggerates High-Fat Diet-induced Cardiomyopathy Journal of the American College of Surgeons. 219: S33-S34. DOI: 10.1016/J.Jamcollsurg.2014.07.071  0.317
2013 Reyskens KM, Fisher TL, Schisler JC, O'Connor WG, Rogers AB, Willis MS, Planesse C, Boyer F, Rondeau P, Bourdon E, Essop MF. Cardio-metabolic effectsof HIV protease inhibitors (lopinavir/ritonavir). Plos One. 8: e73347. PMID 24098634 DOI: 10.1371/Journal.Pone.0073347  0.385
2013 Oakley RH, Ren R, Cruz-Topete D, Bird GS, Myers PH, Boyle MC, Schneider MD, Willis MS, Cidlowski JA. Essential role of stress hormone signaling in cardiomyocytes for the prevention of heart disease. Proceedings of the National Academy of Sciences of the United States of America. 110: 17035-40. PMID 24082121 DOI: 10.1073/Pnas.1302546110  0.392
2013 O'Neal WT, Griffin WF, Dries-Devlin JL, Kent SD, Chen J, Willis MS, Virag JA. Ephrin-Eph signaling as a potential therapeutic target for the treatment of myocardial infarction. Medical Hypotheses. 80: 738-44. PMID 23562676 DOI: 10.1016/J.Mehy.2013.02.024  0.321
2013 Willis MS, Min JN, Wang S, McDonough H, Lockyer P, Wadosky KM, Patterson C. Carboxyl terminus of Hsp70-interacting protein (CHIP) is required to modulate cardiac hypertrophy and attenuate autophagy during exercise. Cell Biochemistry and Function. 31: 724-35. PMID 23553918 DOI: 10.1002/Cbf.2962  0.364
2013 Willis MS, Patterson C. Proteotoxicity and cardiac dysfunction--Alzheimer's disease of the heart? The New England Journal of Medicine. 368: 455-64. PMID 23363499 DOI: 10.1056/Nejmra1106180  0.366
2013 Der-Torossian H, Wysong A, Shadfar S, Willis MS, McDunn J, Couch ME. Metabolic derangements in the gastrocnemius and the effect of Compound A therapy in a murine model of cancer cachexia. Journal of Cachexia, Sarcopenia and Muscle. 4: 145-55. PMID 23344889 DOI: 10.1007/S13539-012-0101-7  0.308
2013 Willis MS, Dyer LA, Ren R, Lockyer P, Moreno-Miralles I, Schisler JC, Patterson C. BMPER regulates cardiomyocyte size and vessel density in vivo. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 22: 228-40. PMID 23200275 DOI: 10.1016/J.Carpath.2012.10.005  0.364
2012 Warren SA, Briggs LE, Zeng H, Chuang J, Chang EI, Terada R, Li M, Swanson MS, Lecker SH, Willis MS, Spinale FG, Maupin-Furlowe J, McMullen JR, Moss RL, Kasahara H. Myosin light chain phosphorylation is critical for adaptation to cardiac stress. Circulation. 126: 2575-88. PMID 23095280 DOI: 10.1161/Circulationaha.112.116202  0.346
2012 Willis MS, Homeister JW, Rosson GB, Annayev Y, Holley D, Holly SP, Madden VJ, Godfrey V, Parise LV, Bultman SJ. Functional redundancy of SWI/SNF catalytic subunits in maintaining vascular endothelial cells in the adult heart. Circulation Research. 111: e111-22. PMID 22740088 DOI: 10.1161/Circresaha.112.265587  0.317
2012 Duan J, Gherghe C, Liu D, Hamlett E, Srikantha L, Rodgers L, Regan JN, Rojas M, Willis M, Leask A, Majesky M, Deb A. Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair. The Embo Journal. 31: 429-42. PMID 22085926 DOI: 10.1038/Emboj.2011.418  0.343
2012 Portbury AL, Ronnebaum SM, Zungu M, Patterson C, Willis MS. Back to your heart: ubiquitin proteasome system-regulated signal transduction. Journal of Molecular and Cellular Cardiology. 52: 526-37. PMID 22085703 DOI: 10.1016/J.Yjmcc.2011.10.023  0.374
2012 Anderson EJ, Katunga LA, Willis MS. Mitochondria as a source and target of lipid peroxidation products in healthy and diseased heart. Clinical and Experimental Pharmacology & Physiology. 39: 179-93. PMID 22066679 DOI: 10.1111/J.1440-1681.2011.05641.X  0.351
2012 Wadosky KM, Willis MS. The story so far: post-translational regulation of peroxisome proliferator-activated receptors by ubiquitination and SUMOylation. American Journal of Physiology. Heart and Circulatory Physiology. 302: H515-26. PMID 22037188 DOI: 10.1152/Ajpheart.00703.2011  0.349
2011 Jensen BC, Willis MS. Edge of the world: practical considerations and a clinical perspective of next-generation sequencing for hereditary cardiac disease. Expert Opinion On Medical Diagnostics. 5: 5-8. PMID 23484472 DOI: 10.1517/17530059.2010.541239  0.318
2011 Zungu M, Schisler J, Willis MS. All the little pieces. -Regulation of mitochondrial fusion and fission by ubiquitin and small ubiquitin-like modifer and their potential relevance in the heart.-. Circulation Journal : Official Journal of the Japanese Circulation Society. 75: 2513-21. PMID 22001293 DOI: 10.1253/Circj.Cj-11-0967  0.359
2011 Carll AP, Haykal-Coates N, Winsett DW, Hazari MS, Nyska A, Richards JH, Willis MS, Costa DL, Farraj AK. Dietary salt exacerbates isoproterenol-induced cardiomyopathy in rats. Toxicologic Pathology. 39: 925-37. PMID 21878552 DOI: 10.1177/0192623311416373  0.308
2011 Wadosky KM, Li L, Rodríguez JE, Min JN, Bogan D, Gonzalez J, Patterson C, Kornegay JN, Willis M. Regulation of the calpain and ubiquitin-proteasome systems in a canine model of muscular dystrophy. Muscle & Nerve. 44: 553-62. PMID 21826685 DOI: 10.1002/Mus.22125  0.331
2011 Patterson C, Portbury AL, Schisler JC, Willis MS. Tear me down: role of calpain in the development of cardiac ventricular hypertrophy. Circulation Research. 109: 453-62. PMID 21817165 DOI: 10.1161/Circresaha.110.239749  0.364
2011 Shadfar S, Couch ME, McKinney KA, Weinstein LJ, Yin X, Rodríguez JE, Guttridge DC, Willis M. Oral resveratrol therapy inhibits cancer-induced skeletal muscle and cardiac atrophy in vivo. Nutrition and Cancer. 63: 749-62. PMID 21660860 DOI: 10.1080/01635581.2011.563032  0.336
2011 Wysong A, Couch M, Shadfar S, Li L, Li L, Rodriguez JE, Asher S, Yin X, Gore M, Baldwin A, Patterson C, Willis MS. NF-κB inhibition protects against tumor-induced cardiac atrophy in vivo. The American Journal of Pathology. 178: 1059-68. PMID 21356358 DOI: 10.1016/J.Ajpath.2010.12.009  0.644
2011 Li HH, Du J, Fan YN, Zhang ML, Liu DP, Li L, Lockyer P, Kang EY, Patterson C, Willis MS. The ubiquitin ligase MuRF1 protects against cardiac ischemia/reperfusion injury by its proteasome-dependent degradation of phospho-c-Jun. The American Journal of Pathology. 178: 1043-58. PMID 21356357 DOI: 10.1016/J.Ajpath.2010.11.049  0.369
2011 Carll AP, Willis MS, Lust RM, Costa DL, Farraj AK. Merits of non-invasive rat models of left ventricular heart failure. Cardiovascular Toxicology. 11: 91-112. PMID 21279739 DOI: 10.1007/S12012-011-9103-5  0.329
2011 Portbury AL, Willis MS, Patterson C. Tearin' up my heart: proteolysis in the cardiac sarcomere. The Journal of Biological Chemistry. 286: 9929-34. PMID 21257759 DOI: 10.1074/Jbc.R110.170571  0.373
2011 Ellis JM, Mentock SM, Depetrillo MA, Koves TR, Sen S, Watkins SM, Muoio DM, Cline GW, Taegtmeyer H, Shulman GI, Willis MS, Coleman RA. Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs Fatty Acid oxidation and induces cardiac hypertrophy. Molecular and Cellular Biology. 31: 1252-62. PMID 21245374 DOI: 10.1128/Mcb.01085-10  0.355
2011 Zungu M, Schisler JC, Essop MF, McCudden C, Patterson C, Willis MS. Regulation of AMPK by the ubiquitin proteasome system. The American Journal of Pathology. 178: 4-11. PMID 21224036 DOI: 10.1016/J.Ajpath.2010.11.030  0.392
2011 Banet N, Gordon C, Willis M, Gilligan P, Thorne L. Unexpected death in a heart transplant recipient Laboratory Medicine. 42: 6-10. DOI: 10.1309/Lml5D5Ewmzzgyech  0.312
2010 Willis MS, Patterson C. Hold me tight: Role of the heat shock protein family of chaperones in cardiac disease. Circulation. 122: 1740-51. PMID 20975010 DOI: 10.1161/Circulationaha.110.942250  0.382
2010 Adamo CM, Dai DF, Percival JM, Minami E, Willis MS, Patrucco E, Froehner SC, Beavo JA. Sildenafil reverses cardiac dysfunction in the mdx mouse model of Duchenne muscular dystrophy. Proceedings of the National Academy of Sciences of the United States of America. 107: 19079-83. PMID 20956307 DOI: 10.1073/Pnas.1013077107  0.387
2010 Rodríguez JE, Willis MS. The therapeutic potential of heat shock proteins in cardiomyopathies due to mutations in cardiac structural proteins. Journal of Molecular and Cellular Cardiology. 49: 904-7. PMID 20920511 DOI: 10.1016/J.Yjmcc.2010.09.022  0.31
2010 Thiele GM, Duryee MJ, Willis MS, Tuma DJ, Radio SJ, Hunter CD, Schaffert CS, Klassen LW. Autoimmune hepatitis induced by syngeneic liver cytosolic proteins biotransformed by alcohol metabolites. Alcoholism, Clinical and Experimental Research. 34: 2126-36. PMID 20860619 DOI: 10.1111/J.1530-0277.2010.01309.X  0.552
2010 Willis MS, Zungu M, Patterson C. Cardiac muscle ring finger-1--friend or foe? Trends in Cardiovascular Medicine. 20: 12-6. PMID 20685572 DOI: 10.1016/J.Tcm.2010.03.001  0.376
2010 Callis TE, Jensen BC, Weck KE, Willis MS. Evolving molecular diagnostics for familial cardiomyopathies: at the heart of it all. Expert Review of Molecular Diagnostics. 10: 329-51. PMID 20370590 DOI: 10.1586/Erm.10.13  0.312
2010 Willis MS, Townley-Tilson WH, Kang EY, Homeister JW, Patterson C. Sent to destroy: the ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease. Circulation Research. 106: 463-78. PMID 20167943 DOI: 10.1161/Circresaha.109.208801  0.364
2010 Lockyer P, Schisler JC, Patterson C, Willis MS. Minireview: Won't get fooled again: the nonmetabolic roles of peroxisome proliferator-activated receptors (PPARs) in the heart. Molecular Endocrinology (Baltimore, Md.). 24: 1111-9. PMID 20016041 DOI: 10.1210/Me.2009-0374  0.364
2010 Mearini G, Gedicke C, Schlossarek S, Witt CC, Krämer E, Cao P, Gomes MD, Lecker SH, Labeit S, Willis MS, Eschenhagen T, Carrier L. Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms. Cardiovascular Research. 85: 357-66. PMID 19850579 DOI: 10.1093/Cvr/Cvp348  0.338
2010 Jearawiriyapaisarn N, Moulton HM, Sazani P, Kole R, Willis MS. Long-term improvement in mdx cardiomyopathy after therapy with peptide-conjugated morpholino oligomers. Cardiovascular Research. 85: 444-53. PMID 19815563 DOI: 10.1093/Cvr/Cvp335  0.351
2010 Carrier L, Schlossarek S, Willis MS, Eschenhagen T. The ubiquitin-proteasome system and nonsense-mediated mRNA decay in hypertrophic cardiomyopathy. Cardiovascular Research. 85: 330-8. PMID 19617224 DOI: 10.1093/Cvr/Cvp247  0.347
2010 Zungu M, Rodriguez JE, Li L, Willis MS. Increased expression of the cardiac ubiquitin ligase MuRF1 alters mitochondrial bioenergetic capacity in vivo Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1797: 139. DOI: 10.1016/J.Bbabio.2010.04.415  0.631
2009 Rodríguez JE, Schisler JC, Patterson C, Willis MS. Seek and destroy: the ubiquitin----proteasome system in cardiac disease. Current Hypertension Reports. 11: 396-405. PMID 19895750 DOI: 10.1007/S11906-009-0069-7  0.406
2009 Willis MS, Schisler JC, Li L, Rodríguez JE, Hilliard EG, Charles PC, Patterson C. Cardiac muscle ring finger-1 increases susceptibility to heart failure in vivo. Circulation Research. 105: 80-8. PMID 19498199 DOI: 10.1161/Circresaha.109.194928  0.414
2009 Rodríguez JE, McCudden CR, Willis MS. Familial hypertrophic cardiomyopathy: basic concepts and future molecular diagnostics. Clinical Biochemistry. 42: 755-65. PMID 19318019 DOI: 10.1016/J.Clinbiochem.2009.01.020  0.318
2009 Willis MS, Rojas M, Li L, Selzman CH, Tang RH, Stansfield WE, Rodriguez JE, Glass DJ, Patterson C. Muscle ring finger 1 mediates cardiac atrophy in vivo. American Journal of Physiology. Heart and Circulatory Physiology. 296: H997-H1006. PMID 19168726 DOI: 10.1152/Ajpheart.00660.2008  0.649
2009 Willis MS, Schisler JC, Portbury AL, Patterson C. Build it up-Tear it down: protein quality control in the cardiac sarcomere. Cardiovascular Research. 81: 439-48. PMID 18974044 DOI: 10.1093/Cvr/Cvn289  0.372
2008 Willis MS, Schisler JC, Patterson C. Appetite for destruction: E3 ubiquitin-ligase protection in cardiac disease. Future Cardiology. 4: 65-75. PMID 19543439 DOI: 10.2217/14796678.4.1.65  0.394
2008 Mearini G, Schlossarek S, Willis MS, Carrier L. The ubiquitin-proteasome system in cardiac dysfunction. Biochimica Et Biophysica Acta. 1782: 749-63. PMID 18634872 DOI: 10.1016/J.Bbadis.2008.06.009  0.383
2008 Duryee MJ, Klassen LW, Jones BL, Willis MS, Tuma DJ, Thiele GM. Increased immunogenicity to P815 cells modified with malondialdehyde and acetaldehyde. International Immunopharmacology. 8: 1112-8. PMID 18550015 DOI: 10.1016/J.Intimp.2008.03.022  0.536
2008 Schisler JC, Willis MS, Patterson C. You spin me round: MaFBx/Atrogin-1 feeds forward on FOXO transcription factors (like a record). Cell Cycle (Georgetown, Tex.). 7: 440-3. PMID 18235241 DOI: 10.4161/Cc.7.4.5451  0.341
2008 Stansfield WE, Tang RH, Moss NC, Baldwin AS, Willis MS, Selzman CH. Proteasome inhibition promotes regression of left ventricular hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 294: H645-50. PMID 18032525 DOI: 10.1152/Ajpheart.00196.2007  0.315
2007 Clarke BA, Drujan D, Willis MS, Murphy LO, Corpina RA, Burova E, Rakhilin SV, Stitt TN, Patterson C, Latres E, Glass DJ. The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle. Cell Metabolism. 6: 376-85. PMID 17983583 DOI: 10.1016/J.Cmet.2007.09.009  0.323
2007 Li HH, Willis MS, Lockyer P, Miller N, McDonough H, Glass DJ, Patterson C. Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins. The Journal of Clinical Investigation. 117: 3211-23. PMID 17965779 DOI: 10.1172/Jci31757  0.404
2007 Stansfield WE, Moss NC, Willis MS, Tang R, Selzman CH. Proteasome inhibition attenuates infarct size and preserves cardiac function in a murine model of myocardial ischemia-reperfusion injury. The Annals of Thoracic Surgery. 84: 120-5. PMID 17588397 DOI: 10.1016/J.Athoracsur.2007.02.049  0.31
2007 Willis MS, Snyder JA, Poppenga RH, Grenache DG. Bovine cardiac troponin T is not accurately quantified with a common human clinical immunoassay. Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 19: 106-8. PMID 17459843 DOI: 10.1177/104063870701900119  0.317
2007 Patterson C, Ike C, Willis PW, Stouffer GA, Willis MS. The bitter end: the ubiquitin-proteasome system and cardiac dysfunction. Circulation. 115: 1456-63. PMID 17372187 DOI: 10.1161/Circulationaha.106.649863  0.372
2007 Willis MS, Ike C, Li L, Wang DZ, Glass DJ, Patterson C. Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo. Circulation Research. 100: 456-9. PMID 17272810 DOI: 10.1161/01.Res.0000259559.48597.32  0.414
2006 Ramana KV, Willis MS, White MD, Horton JW, DiMaio JM, Srivastava D, Bhatnagar A, Srivastava SK. Endotoxin-induced cardiomyopathy and systemic inflammation in mice is prevented by aldose reductase inhibition. Circulation. 114: 1838-46. PMID 17030682 DOI: 10.1161/Circulationaha.106.630830  0.353
2006 Willis MS, Patterson C. Into the heart: the emerging role of the ubiquitin-proteasome system. Journal of Molecular and Cellular Cardiology. 41: 567-79. PMID 16949602 DOI: 10.1016/J.Yjmcc.2006.07.015  0.381
2005 Thiele GM, Duryee MJ, Freeman TL, Sorrell MF, Willis MS, Tuma DJ, Klassen LW. Rat sinusoidal liver endothelial cells (SECs) produce pro-fibrotic factors in response to adducts formed from the metabolites of ethanol. Biochemical Pharmacology. 70: 1593-600. PMID 16202982 DOI: 10.1016/J.Bcp.2005.08.014  0.557
2005 Duryee MJ, Freeman TL, Willis MS, Hunter CD, Hamilton BC, Suzuki H, Tuma DJ, Klassen LW, Thiele GM. Scavenger receptors on sinusoidal liver endothelial cells are involved in the uptake of aldehyde-modified proteins. Molecular Pharmacology. 68: 1423-30. PMID 16105988 DOI: 10.1124/Mol.105.016121  0.548
2005 Carlson DL, Willis MS, White DJ, Norton JW, Giroir BP. Tumor necrosis factor-α-induced caspase activation mediates endotoxin-related cardiac dysfunction Critical Care Medicine. 33: 1021-1028. PMID 15891331 DOI: 10.1097/01.Ccm.0000163398.79679.66  0.337
2005 Willis MS, Carlson DL, Dimaio JM, White MD, White DJ, Adams GA, Horton JW, Giroir BP. Macrophage migration inhibitory factor mediates late cardiac dysfunction after burn injury. American Journal of Physiology. Heart and Circulatory Physiology. 288: H795-804. PMID 15388499 DOI: 10.1152/Ajpheart.00189.2004  0.351
2004 Duryee MJ, Klassen LW, Freeman TL, Willis MS, Tuma DJ, Thiele GM. Lipopolysaccharide is a cofactor for malondialdehyde-acetaldehyde adduct-mediated cytokine/chemokine release by rat sinusoidal liver endothelial and Kupffer cells. Alcoholism, Clinical and Experimental Research. 28: 1931-8. PMID 15608611 DOI: 10.1097/01.Alc.0000148115.90045.C5  0.552
2004 Duryee MJ, Willis MS, Freeman TL, Kuszynski CA, Tuma DJ, Klassen LW, Thiele GM. Mechanisms of alcohol liver damage: aldehydes, scavenger receptors, and autoimmunity. Frontiers in Bioscience : a Journal and Virtual Library. 9: 3145-55. PMID 15353344 DOI: 10.2741/1467  0.563
2004 Willis MS, Klassen LW, Carlson DL, Brouse CF, Thiele GM. Malondialdehyde-acetaldehyde haptenated protein binds macrophage scavenger receptor(s) and induces lysosomal damage. International Immunopharmacology. 4: 885-99. PMID 15182728 DOI: 10.1016/J.Intimp.2004.04.004  0.568
2004 Thiele GM, Duryee MJ, Willis MS, Sorrell MF, Freeman TL, Tuma DJ, Klassen LW. Malondialdehyde-acetaldehyde (MAA) modified proteins induce pro-inflammatory and pro-fibrotic responses by liver endothelial cells. Comparative Hepatology. 3: S25. PMID 14960177 DOI: 10.1186/1476-5926-2-S1-S25  0.562
2004 Klassen LW, Freeman TL, Duryee MJ, Willis MS, Tuma DJ, Thiele GM. MALONDIALDEHYDE-ACETALDEHYDE ADDUCTS: THE 2004 UPDATE. Alcoholism: Clinical & Experimental Research. 28: 67A. DOI: 10.1097/00000374-200408002-00364  0.474
2004 Thiele GM, Freeman TL, Duryee MJ, Willis MS, Tuma DJ, Klassen LW. SINUSOIDAL ENDOTHELIAL CELLS AND KUPFFER CELLS RESPOND TO PROTEINS MODIFIED BY ALDEHYDES PRODUCED UNDER OXIDATIVE STRESS. Alcoholism: Clinical & Experimental Research. 28: 55A. DOI: 10.1097/00000374-200408002-00288  0.512
2003 Duryee MJ, Klassen LW, Freeman TL, Willis MS, Tuma DJ, Thiele GM. Chronic ethanol consumption impairs receptor-mediated endocytosis of MAA-modified albumin by liver endothelial cells. Biochemical Pharmacology. 66: 1045-54. PMID 12963492 DOI: 10.1016/S0006-2952(03)00416-7  0.539
2003 Garner LB, Willis MS, Carlson DL, DiMaio JM, White MD, White DJ, Adams GA, Horton JW, Giroir BP. Macrophage migration inhibitory factor is a cardiac-derived myocardial depressant factor. American Journal of Physiology. Heart and Circulatory Physiology. 285: H2500-9. PMID 12946935 DOI: 10.1152/Ajpheart.00432.2003  0.38
2003 Willis MS, Thiele GM, Tuma DJ, Klassen LW. T cell proliferative responses to malondialdehyde-acetaldehyde haptenated protein are scavenger receptor mediated. International Immunopharmacology. 3: 1381-99. PMID 12946435 DOI: 10.1016/S1567-5769(03)00136-X  0.546
2003 THIELE G, FREEMAN T, DURYEE M, WILLIS M, TUMA D, KLASSEN L. 1019 Lipopolysaccharide as a co-factor for malondialdehyde-acetaldehyde (MAA) modified proteins to induce pro-inflammatory responses by Kupffer and liver endothelial cells Hepatology. 38: 647-647. DOI: 10.1016/S0270-9139(03)81057-1  0.543
2003 THIELE G, FREEMAN T, WILLIS M, HUNTER C, TUMA D, KLASSEN L. 679 Identification of liver cytosolic proteins associated with malondialdehyde-acetaldehyde (MAA) adducted liver cytosol induced autoimmune hepatitis Hepatology. 38: 488-488. DOI: 10.1016/S0270-9139(03)80721-8  0.522
2002 Willis MS, Klassen LW, Tuma DJ, Sorrell MF, Thiele GM. In vitro exposure to malondialdehyde-acetaldehyde adducted protein inhibits cell proliferation and viability. Alcoholism, Clinical and Experimental Research. 26: 158-64. PMID 11964554 DOI: 10.1111/J.1530-0277.2002.Tb02520.X  0.568
2002 Willis MS, Klassen LW, Tuma DJ, Thiele GM. Malondialdehyde-acetaldehyde-haptenated protein induces cell death by induction of necrosis and apoptosis in immune cells. International Immunopharmacology. 2: 519-35. PMID 11962731 DOI: 10.1016/S1567-5769(01)00195-3  0.561
2002 Willis MS, Klassen LW, Tuma DJ, Sorrell MF, Thiele GM. Adduction of soluble proteins with malondialdehyde-acetaldehyde (MAA) induces antibody production and enhances T-cell proliferation. Alcoholism, Clinical and Experimental Research. 26: 94-106. PMID 11821659 DOI: 10.1111/J.1530-0277.2002.Tb02436.X  0.544
1998 Thiele GM, Tuma DJ, Willis MS, Miller JA, McDonald TL, Sorrell MF, Klassen LW. Soluble Proteins Modified with Acetaldehyde and Malondialdehyde Are Immunogenic in the Absence of Adjuvant Alcoholism: Clinical and Experimental Research. 22: 1731-1739. DOI: 10.1111/J.1530-0277.1998.Tb03973.X  0.55
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