| Year |
Citation |
Score |
| 2023 |
De Santis R, Rice E, Croft G, Yang M, Rosado-Olivieri EA, Brivanlou AH. The emergence of human gastrulation upon in vitro attachment. Stem Cell Reports. 19: 41-53. PMID 38101401 DOI: 10.1016/j.stemcr.2023.11.005 |
0.357 |
|
| 2022 |
Yoney A, Bai L, Brivanlou AH, Siggia ED. Mechanisms underlying WNT-mediated priming of human embryonic stem cells. Development (Cambridge, England). 149. PMID 35815787 DOI: 10.1242/dev.200335 |
0.451 |
|
| 2022 |
Simunovic M, Siggia ED, Brivanlou AH. In vitro attachment and symmetry breaking of a human embryo model assembled from primed embryonic stem cells. Cell Stem Cell. 29: 962-972.e4. PMID 35659878 DOI: 10.1016/j.stem.2022.05.001 |
0.388 |
|
| 2022 |
Piccolo FM, Kastan NR, Haremaki T, Tian Q, Laundos TL, De Santis R, Beaudoin AJ, Carroll TS, Luo JD, Gnedeva K, Etoc F, Hudspeth AJ, Brivanlou AH. Role of YAP in early ectodermal specification and a Huntington's Disease model of human neurulation. Elife. 11. PMID 35451959 DOI: 10.7554/eLife.73075 |
0.383 |
|
| 2021 |
De Santis R, Etoc F, Rosado-Olivieri EA, Brivanlou AH. Self-organization of human dorsal-ventral forebrain structures by light induced SHH. Nature Communications. 12: 6768. PMID 34799555 DOI: 10.1038/s41467-021-26881-w |
0.36 |
|
| 2021 |
Valet M, Siggia ED, Brivanlou AH. Mechanical regulation of early vertebrate embryogenesis. Nature Reviews. Molecular Cell Biology. PMID 34754086 DOI: 10.1038/s41580-021-00424-z |
0.418 |
|
| 2021 |
Galgoczi S, Ruzo A, Markopoulos C, Yoney A, Phan-Everson T, Li S, Haremaki T, Metzger JJ, Etoc F, Brivanlou AH. Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects. Development (Cambridge, England). 148. PMID 34608934 DOI: 10.1242/dev.199513 |
0.324 |
|
| 2021 |
De Santis R, Brivanlou AH. The treasure inside human naive pluripotency, generation of trophectoderm and blastoids. Cell Stem Cell. 28: 985-987. PMID 34087157 DOI: 10.1016/j.stem.2021.05.010 |
0.397 |
|
| 2021 |
Clark AT, Brivanlou A, Fu J, Kato K, Mathews D, Niakan KK, Rivron N, Saitou M, Surani A, Tang F, Rossant J. Human embryo research, stem cell-derived embryo models and in vitro gametogenesis: Considerations leading to the revised ISSCR guidelines. Stem Cell Reports. PMID 34048690 DOI: 10.1016/j.stemcr.2021.05.008 |
0.331 |
|
| 2021 |
Yang M, Rito T, Metzger J, Naftaly J, Soman R, Hu J, Albertini DF, Barad DH, Brivanlou AH, Gleicher N. Depletion of aneuploid cells in human embryos and gastruloids. Nature Cell Biology. 23: 314-321. PMID 33837289 DOI: 10.1038/s41556-021-00660-7 |
0.33 |
|
| 2019 |
Haremaki T, Metzger JJ, Rito T, Ozair MZ, Etoc F, Brivanlou AH. Self-organizing neuruloids model developmental aspects of Huntington's disease in the ectodermal compartment. Nature Biotechnology. PMID 31501559 DOI: 10.1038/S41587-019-0237-5 |
0.765 |
|
| 2019 |
Martyn I, Siggia ED, Brivanlou AH. Mapping cell migrations and fates in a gastruloid model to the human primitive streak. Development (Cambridge, England). 146. PMID 31427289 DOI: 10.1242/Dev.179564 |
0.31 |
|
| 2019 |
Simunovic M, Metzger JJ, Etoc F, Yoney A, Ruzo A, Martyn I, Croft G, You DS, Brivanlou AH, Siggia ED. A 3D model of a human epiblast reveals BMP4-driven symmetry breaking. Nature Cell Biology. 21: 900-910. PMID 31263269 DOI: 10.1038/s41556-019-0349-7 |
0.38 |
|
| 2019 |
Martyn I, Kanno TY, Brivanlou AH. Chick Models and Human-Chick Organizer Grafts. Methods in Molecular Biology (Clifton, N.J.). 2005: 77-89. PMID 31175647 DOI: 10.1007/978-1-4939-9524-0_6 |
0.4 |
|
| 2019 |
Etoc F, Brivanlou A. A boost towards totipotency for stem cells. Nature Cell Biology. 21: 671-673. PMID 31160707 DOI: 10.1038/s41556-019-0340-3 |
0.489 |
|
| 2019 |
Martyn I, Brivanlou AH, Siggia ED. A wave of WNT signaling balanced by secreted inhibitors controls primitive streak formation in micropattern colonies of human embryonic stem cells. Development (Cambridge, England). 146. PMID 30814117 DOI: 10.1242/Dev.172791 |
0.34 |
|
| 2018 |
Yoney A, Etoc F, Ruzo A, Carroll T, Metzger JJ, Martyn I, Li S, Kirst C, Siggia ED, Brivanlou AH. WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids. Elife. 7. PMID 30311909 DOI: 10.7554/Elife.38279 |
0.311 |
|
| 2018 |
Metzger JJ, Simunovic M, Brivanlou AH. Synthetic embryology: controlling geometry to model early mammalian development. Current Opinion in Genetics & Development. 52: 86-91. PMID 29957587 DOI: 10.1016/j.gde.2018.06.006 |
0.351 |
|
| 2018 |
Ozair MZ, Kirst C, van den Berg BL, Ruzo A, Rito T, Brivanlou AH. hPSC Modeling Reveals that Fate Selection of Cortical Deep Projection Neurons Occurs in the Subplate. Cell Stem Cell. PMID 29937203 DOI: 10.1016/J.Stem.2018.05.024 |
0.704 |
|
| 2017 |
Waisman A, Echegaray CV, Solari C, Cosentino MS, Martyn I, Deglincerti A, Ozair MZ, Matias AR, Barañao L, Miriuka S, Brivanlou A, Guberman A. Inhibition of cell division and DNA replication impair mouse naïve pluripotency exit. Journal of Molecular Biology. PMID 28684247 DOI: 10.1016/J.Jmb.2017.06.020 |
0.726 |
|
| 2017 |
Qi Y, Zhang XJ, Renier N, Wu Z, Atkin T, Sun Z, Ozair MZ, Tchieu J, Zimmer B, Fattahi F, Ganat Y, Azevedo R, Zeltner N, Brivanlou AH, Karayiorgou M, et al. Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells. Nature Biotechnology. PMID 28112759 DOI: 10.1038/Nbt.3777 |
0.721 |
|
| 2017 |
Kanno TYN, Yan CYI, Brivanlou A. Role of Scratch2 in mouse embryonic stem cells cortical differentiation Mechanisms of Development. 145: S175. DOI: 10.1016/j.mod.2017.04.509 |
0.476 |
|
| 2016 |
Etoc F, Metzger J, Ruzo A, Kirst C, Yoney A, Ozair MZ, Brivanlou AH, Siggia ED. A Balance between Secreted Inhibitors and Edge Sensing Controls Gastruloid Self-Organization. Developmental Cell. PMID 27746044 DOI: 10.1016/J.Devcel.2016.09.016 |
0.75 |
|
| 2016 |
Deglincerti A, Etoc F, Guerra MC, Martyn I, Metzger J, Ruzo A, Simunovic M, Yoney A, Brivanlou AH, Siggia E, Warmflash A. Self-organization of human embryonic stem cells on micropatterns. Nature Protocols. 11: 2223-2232. PMID 27735934 DOI: 10.1038/Nprot.2016.131 |
0.401 |
|
| 2016 |
Deglincerti A, Croft GF, Pietila LN, Zernicka-Goetz M, Siggia ED, Brivanlou AH. Self-organization of the in vitro attached human embryo. Nature. PMID 27144363 DOI: 10.1038/Nature17948 |
0.407 |
|
| 2016 |
Deglincerti A, Etoc F, Ozair MZ, Brivanlou AH. Self-Organization of Spatial Patterning in Human Embryonic Stem Cells. Current Topics in Developmental Biology. 116: 99-113. PMID 26970615 DOI: 10.1016/Bs.Ctdb.2015.11.010 |
0.737 |
|
| 2016 |
Sato N, Brivanlou A. Microarray Approach to Identify the Signaling Network Responsible for Self-Renewal of Human Embryonic Stem Cells. Methods in Molecular Biology (Clifton, N.J.). 1307: 71-88. PMID 25990842 DOI: 10.1007/7651_2015_244 |
0.33 |
|
| 2016 |
Deglincerti A, Etoc F, Ozair MZ, Brivanlou AH. Self-Organization of Spatial Patterning in Human Embryonic Stem Cells Current Topics in Developmental Biology. DOI: 10.1016/bs.ctdb.2015.11.010 |
0.731 |
|
| 2015 |
Deglincerti A, Brivanlou AH. The generation of sex cells. Cell Research. 25: 267-8. PMID 25698577 DOI: 10.1038/Cr.2015.18 |
0.373 |
|
| 2014 |
Warmflash A, Sorre B, Etoc F, Siggia ED, Brivanlou AH. A method to recapitulate early embryonic spatial patterning in human embryonic stem cells. Nature Methods. 11: 847-54. PMID 24973948 DOI: 10.1038/Nmeth.3016 |
0.418 |
|
| 2013 |
Bates TJ, Vonica A, Heasman J, Brivanlou AH, Bell E. Coco regulates dorsoventral specification of germ layers via inhibition of TGFβ signalling. Development (Cambridge, England). 140: 4177-81. PMID 24026124 DOI: 10.1242/Dev.095521 |
0.312 |
|
| 2013 |
Ozair MZ, Kintner C, Brivanlou AH. Neural induction and early patterning in vertebrates. Wiley Interdisciplinary Reviews. Developmental Biology. 2: 479-98. PMID 24014419 DOI: 10.1002/Wdev.90 |
0.781 |
|
| 2013 |
Rosa A, Brivanlou AH. Regulatory non-coding RNAs in pluripotent stem cells. International Journal of Molecular Sciences. 14: 14346-73. PMID 23852015 DOI: 10.3390/ijms140714346 |
0.346 |
|
| 2013 |
Ozair MZ, Noggle S, Warmflash A, Krzyspiak JE, Brivanlou AH. SMAD7 directly converts human embryonic stem cells to telencephalic fate by a default mechanism. Stem Cells (Dayton, Ohio). 31: 35-47. PMID 23034881 DOI: 10.1002/Stem.1246 |
0.768 |
|
| 2013 |
Singh H, Brivanlou AH. The Molecular Circuitry Underlying Pluripotency in Embryonic Stem Cells and iPS Cells Handbook of Stem Cells. 1: 29-35. DOI: 10.1016/B978-0-12-385942-6.00005-6 |
0.347 |
|
| 2012 |
Warmflash A, Siggia ED, Brivanlou AH. Signaling dynamics and embryonic development. Cell Cycle (Georgetown, Tex.). 11: 3529-30. PMID 22935712 DOI: 10.4161/Cc.21964 |
0.315 |
|
| 2012 |
Arduini BL, Brivanlou AH. Modulation of FOXD3 activity in human embryonic stem cells directs pluripotency and paraxial mesoderm fates. Stem Cells (Dayton, Ohio). 30: 2188-98. PMID 22887036 DOI: 10.1002/Stem.1200 |
0.437 |
|
| 2012 |
Warmflash A, Arduini BL, Brivanlou AH. The molecular circuitry underlying pluripotency in embryonic stem cells. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 4: 443-56. PMID 22761038 DOI: 10.1002/Wsbm.1182 |
0.413 |
|
| 2011 |
Rosa A, Brivanlou AH. A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiation. The Embo Journal. 30: 237-48. PMID 21151097 DOI: 10.1038/emboj.2010.319 |
0.33 |
|
| 2011 |
Arduini B, Brivanlou AH. Role of FoxD3 in maintenance of pluripotency and early lineage segregation in human embryonic stem cells Developmental Biology. 356: 214. DOI: 10.1016/J.Ydbio.2011.05.327 |
0.403 |
|
| 2010 |
Shimomura Y, Agalliu D, Vonica A, Luria V, Wajid M, Baumer A, Belli S, Petukhova L, Schinzel A, Brivanlou AH, Barres BA, Christiano AM. APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex. Nature. 464: 1043-7. PMID 20393562 DOI: 10.1038/Nature08875 |
0.326 |
|
| 2009 |
Rosa A, Brivanlou AH. MicroRNAs in early vertebrate development. Cell Cycle (Georgetown, Tex.). 8: 3513-20. PMID 19875943 |
0.364 |
|
| 2009 |
Lacoste A, Berenshteyn F, Brivanlou AH. An efficient and reversible transposable system for gene delivery and lineage-specific differentiation in human embryonic stem cells. Cell Stem Cell. 5: 332-42. PMID 19733544 DOI: 10.1016/j.stem.2009.07.011 |
0.341 |
|
| 2009 |
Di Pasquale E, Brivanlou AH. Bone morphogenetic protein 15 (BMP15) acts as a BMP and Wnt inhibitor during early embryogenesis. The Journal of Biological Chemistry. 284: 26127-36. PMID 19553676 DOI: 10.1074/jbc.M109.036608 |
0.335 |
|
| 2009 |
Yan CY, Skourides P, Chang C, Brivanlou A. Samba, a Xenopus hnRNP expressed in neural and neural crest tissues. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 204-9. PMID 19097051 DOI: 10.1002/Dvdy.21826 |
0.418 |
|
| 2009 |
Levine AJ, Levine ZJ, Brivanlou AH. GDF3 is a BMP inhibitor that can activate Nodal signaling only at very high doses. Developmental Biology. 325: 43-8. PMID 18823971 DOI: 10.1016/j.ydbio.2008.09.006 |
0.676 |
|
| 2009 |
Lacoste A, Berenshteyn F, Brivanlou AH. An Efficient and Reversible Transposable System for Gene Delivery and Lineage-Specific Differentiation in Human Embryonic Stem Cells (DOI:10.1016/j.stem.2009.07.011) Cell Stem Cell. 5: 568. DOI: 10.1016/j.stem.2009.10.013 |
0.352 |
|
| 2007 |
Dreesen O, Brivanlou AH. Signaling pathways in cancer and embryonic stem cells. Stem Cell Reviews. 3: 7-17. PMID 17873377 DOI: 10.1007/s12015-007-0004-8 |
0.4 |
|
| 2007 |
Levine AJ, Brivanlou AH. Proposal of a model of mammalian neural induction. Developmental Biology. 308: 247-56. PMID 17585896 DOI: 10.1016/j.ydbio.2007.05.036 |
0.703 |
|
| 2007 |
Noggle SA, Spagnoli FM, Brivanlou AH. In vivo Differentiation of Human Embryonic Stem Cells Human Embryonic Stem Cells: the Practical Handbook. 121-147. DOI: 10.1002/9780470511619.ch9 |
0.398 |
|
| 2006 |
Chang C, Brivanlou AH, Harland RM. Function of the two Xenopus smad4s in early frog development. The Journal of Biological Chemistry. 281: 30794-803. PMID 16908518 DOI: 10.1074/Jbc.M607054200 |
0.56 |
|
| 2006 |
Knockaert M, Sapkota G, Alarcón C, Massagué J, Brivanlou AH. Unique players in the BMP pathway: small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling. Proceedings of the National Academy of Sciences of the United States of America. 103: 11940-5. PMID 16882717 DOI: 10.1073/Pnas.0605133103 |
0.302 |
|
| 2006 |
Sato N, Brivanlou AH. Microarray approach to identify the signaling network responsible for self-renewal of human embryonic stem cells. Methods in Molecular Biology (Clifton, N.J.). 331: 267-83. PMID 16881522 DOI: 10.1385/1-59745-046-4:267 |
0.377 |
|
| 2006 |
Sato N, Brivanlou AH. Manipulation of self-renewal in human embryonic stem cells through a novel pharmacological GSK-3 inhibitor. Methods in Molecular Biology (Clifton, N.J.). 331: 115-28. PMID 16881513 DOI: 10.1385/1-59745-046-4:115 |
0.41 |
|
| 2006 |
James D, Noggle SA, Swigut T, Brivanlou AH. Contribution of human embryonic stem cells to mouse blastocysts. Developmental Biology. 295: 90-102. PMID 16769046 DOI: 10.1016/j.ydbio.2006.03.026 |
0.398 |
|
| 2006 |
Levine AJ, Brivanlou AH. GDF3 at the crossroads of TGF-beta signaling. Cell Cycle (Georgetown, Tex.). 5: 1069-73. PMID 16721050 |
0.703 |
|
| 2006 |
Vonica A, Brivanlou AH. An obligatory caravanserai stop on the silk road to neural induction: inhibition of BMP/GDF signaling. Seminars in Cell & Developmental Biology. 17: 117-32. PMID 16516504 DOI: 10.1016/J.Semcdb.2005.11.013 |
0.328 |
|
| 2006 |
Levine AJ, Brivanlou AH. GDF3, a BMP inhibitor, regulates cell fate in stem cells and early embryos. Development (Cambridge, England). 133: 209-16. PMID 16339188 DOI: 10.1242/dev.02192 |
0.747 |
|
| 2005 |
Noggle SA, James D, Brivanlou AH. A molecular basis for human embryonic stem cell pluripotency. Stem Cell Reviews. 1: 111-8. PMID 17142845 DOI: 10.1385/SCR:1:2:111 |
0.444 |
|
| 2005 |
Wysocka J, Swigut T, Milne TA, Dou Y, Zhang X, Burlingame AL, Roeder RG, Brivanlou AH, Allis CD. WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell. 121: 859-72. PMID 15960974 DOI: 10.1016/J.Cell.2005.03.036 |
0.359 |
|
| 2005 |
Spagnoli FM, Brivanlou AH. A full menu for stem-cell research. Genome Biology. 6: 311. PMID 15774038 DOI: 10.1186/gb-2005-6-3-311 |
0.304 |
|
| 2004 |
Sato N, Meijer L, Skaltsounis L, Greengard P, Brivanlou AH. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nature Medicine. 10: 55-63. PMID 14702635 DOI: 10.1038/nm979 |
0.416 |
|
| 2003 |
Meijer L, Skaltsounis AL, Magiatis P, Polychronopoulos P, Knockaert M, Leost M, Ryan XP, Vonica CA, Brivanlou A, Dajani R, Crovace C, Tarricone C, Musacchio A, Roe SM, Pearl L, et al. GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chemistry & Biology. 10: 1255-66. PMID 14700633 DOI: 10.1016/j.chembiol.2003.11.010 |
0.303 |
|
| 2003 |
Sato N, Sanjuan IM, Heke M, Uchida M, Naef F, Brivanlou AH. Molecular signature of human embryonic stem cells and its comparison with the mouse. Developmental Biology. 260: 404-13. PMID 12921741 DOI: 10.1016/S0012-1606(03)00256-2 |
0.417 |
|
| 2003 |
Brivanlou AH, Gage FH, Jaenisch R, Jessell T, Melton D, Rossant J. Stem cells. Setting standards for human embryonic stem cells. Science (New York, N.Y.). 300: 913-6. PMID 12738841 DOI: 10.1126/Science.1082940 |
0.6 |
|
| 2003 |
Chang C, Eggen BJ, Weinstein DC, Brivanlou AH. Regulation of nodal and BMP signaling by tomoregulin-1 (X7365) through novel mechanisms. Developmental Biology. 255: 1-11. PMID 12618130 DOI: 10.1016/S0012-1606(02)00075-1 |
0.352 |
|
| 2003 |
Levine AJ, Munoz-Sanjuan I, Bell E, North AJ, Brivanlou AH. Fluorescent labeling of endothelial cells allows in vivo, continuous characterization of the vascular development of Xenopus laevis. Developmental Biology. 254: 50-67. PMID 12606281 DOI: 10.1016/S0012-1606(02)00029-5 |
0.653 |
|
| 2003 |
Bell E, Muñoz-Sanjuán I, Altmann CR, Vonica A, Brivanlou AH. Cell fate specification and competence by Coco, a maternal BMP, TGFbeta and Wnt inhibitor. Development (Cambridge, England). 130: 1381-9. PMID 12588853 DOI: 10.1242/Dev.00344 |
0.383 |
|
| 2002 |
Muñoz-Sanjuán I, Bell E, Altmann CR, Vonica A, Brivanlou AH. Gene profiling during neural induction in Xenopus laevis: regulation of BMP signaling by post-transcriptional mechanisms and TAB3, a novel TAK1-binding protein. Development (Cambridge, England). 129: 5529-40. PMID 12403722 DOI: 10.1242/Dev.00097 |
0.354 |
|
| 2002 |
Altmann CR, Chang C, Muñoz-Sanjuán I, Bell E, Heke M, Rifkin DB, Brivanlou AH. The latent-TGFbeta-binding-protein-1 (LTBP-1) is expressed in the organizer and regulates nodal and activin signaling. Developmental Biology. 248: 118-27. PMID 12142025 DOI: 10.1006/Dbio.2002.0716 |
0.301 |
|
| 2002 |
Muñoz-Sanjuán I, Brivanlou AH. Neural induction, the default model and embryonic stem cells. Nature Reviews. Neuroscience. 3: 271-80. PMID 11967557 DOI: 10.1038/nrn786 |
0.395 |
|
| 2001 |
Zohn IE, Brivanlou AH. Expression cloning of Xenopus Os4, an evolutionarily conserved gene, which induces mesoderm and dorsal axis. Developmental Biology. 239: 118-31. PMID 11784023 DOI: 10.1006/dbio.2001.0420 |
0.361 |
|
| 2001 |
Chang C, Holtzman DA, Chau S, Chickering T, Woolf EA, Holmgren LM, Bodorova J, Gearing DP, Holmes WE, Brivanlou AH. Twisted gastrulation can function as a BMP antagonist. Nature. 410: 483-7. PMID 11260717 DOI: 10.1038/35068583 |
0.317 |
|
| 2001 |
Altmann CR, Brivanlou AH. Neural patterning in the vertebrate embryo. International Review of Cytology. 203: 447-82. PMID 11131523 |
0.307 |
|
| 1998 |
Casellas R, Brivanlou AH. Xenopus Smad7 inhibits both the activin and BMP pathways and acts as a neural inducer. Developmental Biology. 198: 1-12. PMID 9640328 DOI: 10.1016/S0012-1606(98)80025-0 |
0.327 |
|
| 1990 |
Condie BG, Brivanlou AH, Harland RM. Most of the homeobox-containing Xhox 36 transcripts in early Xenopus embryos cannot encode a homeodomain protein. Molecular and Cellular Biology. 10: 3376-85. PMID 1972542 |
0.667 |
|
| 1989 |
Brivanlou AH, Harland RM. Expression of an engrailed-related protein is induced in the anterior neural ectoderm of early Xenopus embryos. Development (Cambridge, England). 106: 611-7. PMID 2574664 |
0.506 |
|
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