| Year |
Citation |
Score |
| 2021 |
Skibba ME, Xu X, Weiss K, Huisken J, Brasier AR. Role of Secretoglobin (club cell) NFκB/RelA-TGFβ signaling in aero-allergen-induced epithelial plasticity and subepithelial myofibroblast transdifferentiation. Respiratory Research. 22: 315. PMID 34930252 DOI: 10.1186/s12931-021-01910-w |
0.304 |
|
| 2021 |
Xu X, Mann M, Qiao D, Li Y, Zhou J, Brasier AR. Bromodomain Containing Protein 4 (BRD4) Regulates Expression of its Interacting Coactivators in the Innate Response to Respiratory Syncytial Virus. Frontiers in Molecular Biosciences. 8: 728661. PMID 34765643 DOI: 10.3389/fmolb.2021.728661 |
0.308 |
|
| 2021 |
Qiao D, Skibba M, Xu X, Garofalo RP, Zhao Y, Brasier AR. Paramyxovirus replication induces the Hexosamine Biosynthetic Pathway and Mesenchymal Transition via the IRE1a-XBP1s arm of the Unfolded Protein Response. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 34318710 DOI: 10.1152/ajplung.00127.2021 |
0.325 |
|
| 2020 |
Xu X, Qiao D, Mann M, Garofalo RP, Brasier AR. Respiratory Syncytial Virus Infection Induces Chromatin Remodeling to Activate Growth Factor and Extracellular Matrix Secretion Pathways. Viruses. 12. PMID 32722537 DOI: 10.3390/V12080804 |
0.406 |
|
| 2020 |
Brasier AR. RSV Reprograms the CDK9•BRD4 Chromatin Remodeling Complex to Couple Innate Inflammation to Airway Remodeling. Viruses. 12. PMID 32331282 DOI: 10.3390/V12040472 |
0.439 |
|
| 2020 |
Liu Z, Chen H, Wang P, Li Y, Wold EA, Leonard PG, Joseph S, Brasier AR, Tian B, Zhou J. Discovery of Orally Bioavailable Chromone Derivatives as Potent and Selective BRD4 Inhibitors: Scaffolding Hopping, Optimization and Pharmacological Evaluation. Journal of Medicinal Chemistry. PMID 32255647 DOI: 10.1021/Acs.Jmedchem.0C00035 |
0.305 |
|
| 2020 |
Zhao Y, Fang R, Zhang J, Zhang Y, Bechelli J, Smalley C, Valbuena G, Walker DH, Oteo JA, Brasier AR. Quantitative Proteomics of the Endothelial Secretome Identifies RC0497 as Diagnostic of Acute Rickettsial Spotted Fever Infections. The American Journal of Pathology. 190: 306-322. PMID 31955791 DOI: 10.1016/J.Ajpath.2019.10.007 |
0.304 |
|
| 2020 |
Liu Z, Uribe G, Li Y, Pingyuan W, Chen H, Brasier A, Pinchuk I, Zhou J, Tian B. 6 NOVEL BRD4 INHIBITORS BLOCK THE PATHOLOGICAL ACTIVATION OF BRD4-NFκB SIGNALING AND SUPPRESS COLONIC INFLAMMATION IN IBD MOUSE MODELS Gastroenterology. 158: S11. DOI: 10.1053/J.Gastro.2019.11.063 |
0.34 |
|
| 2019 |
Brasier AR, Zhou J. Validation of the epigenetic reader bromodomain-containing protein 4 (BRD4) as a therapeutic target for treatment of airway remodeling. Drug Discovery Today. PMID 31733396 DOI: 10.1016/J.Drudis.2019.11.002 |
0.339 |
|
| 2019 |
Brasier AR, Boldogh I. Targeting inducible epigenetic reprogramming pathways in chronic airway remodeling. Drugs in Context. 8. PMID 31692901 DOI: 10.7573/Dic.2019-8-3 |
0.398 |
|
| 2019 |
Zhang J, Jamaluddin M, Zhang Y, Widen SG, Sun H, Brasier AR, Zhao Y. Type II Epithelial-mesenchymal transition upregulates protein N-glycosylation to maintain proteostasis and extracellular matrix production. Journal of Proteome Research. PMID 31424945 DOI: 10.1021/Acs.Jproteome.9B00342 |
0.341 |
|
| 2019 |
Zhao Y, Bing T, Sun H, Zhang J, Zhang Y, Ivannikov M, Motamedi M, Liu Z, Zhou J, Kaphalia L, Calhoun WJ, Maroto R, Brasier AR. Pharmacoproteomics reveal novel protective activity of bromodomain containing 4 inhibitors on vascular homeostasis in TLR3-mediated airway remodeling. Journal of Proteomics. 103415. PMID 31195152 DOI: 10.1016/J.Jprot.2019.103415 |
0.394 |
|
| 2019 |
Brasier AR. Mechanisms how mucosal innate immunity affects progression of allergic airway disease. Expert Review of Respiratory Medicine. PMID 30712413 DOI: 10.1080/17476348.2019.1578211 |
0.384 |
|
| 2018 |
McDonnell TCR, Willis R, Pericleous C, Ripoll VM, Giles IP, Isenberg DA, Brasier AR, Gonzalez EB, Papalardo E, Romay-Penabad Z, Jamaluddin M, Ioannou Y, Rahman A. PEGylated Domain I of Beta-2-Glycoprotein I Inhibits the Binding, Coagulopathic, and Thrombogenic Properties of IgG From Patients With the Antiphospholipid Syndrome. Frontiers in Immunology. 9: 2413. PMID 30405613 DOI: 10.3389/Fimmu.2018.02413 |
0.305 |
|
| 2018 |
Rayavara K, Kurosky A, J Stafford S, Garg NJ, Brasier AR, Garofalo RP, Hosakote YM. Proinflammatory Effects of Respiratory Syncytial Virus-Induced Epithelial HMGB1 on Human Innate Immune Cell Activation. Journal of Immunology (Baltimore, Md. : 1950). PMID 30275049 DOI: 10.4049/Jimmunol.1800558 |
0.411 |
|
| 2018 |
Brasier AR. Therapeutic targets for inflammation-mediated airway remodeling in chronic lung disease. Expert Review of Respiratory Medicine. 1-9. PMID 30241450 DOI: 10.1080/17476348.2018.1526677 |
0.353 |
|
| 2018 |
Tian B, Widen SG, Yang J, Wood TG, Kudlicki A, Zhao Y, Brasier AR. The NFkB subunit RELA is a master transcriptional regulator of the committed epithelial-mesenchymal transition in airway epithelial cells. The Journal of Biological Chemistry. PMID 30166344 DOI: 10.1074/Jbc.Ra118.003662 |
0.401 |
|
| 2018 |
Tian B, Liu Z, Litvinov J, Maroto R, Jamaluddin M, Rytting E, Patrikeev I, Ochoa L, Vargas G, Motamedi M, Ameredes BT, Zhou J, Brasier AR. Efficacy of Novel Highly Specific Bromodomain-Containing Protein 4 Inhibitors in Innate Inflammation-Driven Airway Remodeling. American Journal of Respiratory Cell and Molecular Biology. PMID 30153047 DOI: 10.1165/Rcmb.2017-0445Oc |
0.369 |
|
| 2018 |
Hao W, Qi T, Pan L, Wang R, Zhu B, Aguilera-Aguirre L, Radak Z, Hazra TK, Vlahopoulos SA, Bacsi A, Brasier AR, Ba X, Boldogh I. Effects of the stimuli-dependent enrichment of 8-oxoguanine DNA glycosylase1 on chromatinized DNA. Redox Biology. 18: 43-53. PMID 29940424 DOI: 10.1016/J.Redox.2018.06.002 |
0.329 |
|
| 2018 |
Tian B, Liu Z, Yang J, Sun H, Zhao Y, Wakamiya M, Chen H, Rytting E, Zhou J, Brasier AR. Selective Antagonists of the Bronchiolar Epithelial NF-κB-Bromodomain-Containing Protein 4 Pathway in Viral-Induced Airway Inflammation. Cell Reports. 23: 1138-1151. PMID 29694891 DOI: 10.1016/J.Celrep.2018.03.106 |
0.459 |
|
| 2018 |
Liu Z, Tian B, Chen H, Wang P, Brasier AR, Zhou J. Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation. European Journal of Medicinal Chemistry. 151: 450-461. PMID 29649741 DOI: 10.1016/J.Ejmech.2018.04.006 |
0.359 |
|
| 2018 |
Tian B, Yang J, Zhao Y, Ivanciuc T, Sun H, Wakamiya M, Garofalo RP, Brasier AR. Central Role of the NFκB Pathway in the-Expressing Epithelium in Mediating Respiratory Syncytial Virus-induced Airway Inflammation. Journal of Virology. PMID 29593031 DOI: 10.1128/Jvi.00441-18 |
0.413 |
|
| 2018 |
Czerkies M, Korwek Z, Prus W, Kochańczyk M, Jaruszewicz-Błońska J, Tudelska K, Błoński S, Kimmel M, Brasier AR, Lipniacki T. Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways. Nature Communications. 9: 493. PMID 29402958 DOI: 10.1038/S41467-017-02640-8 |
0.375 |
|
| 2017 |
Zhang K, Xu P, Sowers JL, Machuca DF, Mirfattah B, Herring J, Tang H, Chen Y, Tian B, Brasier AR, Sowers LC. Proteome analysis of hypoxic glioblastoma cells reveals sequential metabolic adaptation of one-carbon metabolic pathways. Molecular & Cellular Proteomics : McP. PMID 28874504 DOI: 10.1074/Mcp.Ra117.000154 |
0.3 |
|
| 2017 |
Ijaz T, Sun H, Pinchuk IV, Milewicz DM, Tilton RG, Brasier AR. Deletion of NF-κB/RelA in Angiotensin II-Sensitive Mesenchymal Cells Blocks Aortic Vascular Inflammation and Abdominal Aortic Aneurysm Formation. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28818856 DOI: 10.1161/Atvbaha.117.309863 |
0.374 |
|
| 2017 |
Aguilera-Aguirre L, Hao W, Pan L, Li X, Saavedra-Molina A, Bacsi A, Radak Z, Sur S, Brasier AR, Ba X, Boldogh I. Pollen-induced oxidative DNA damage response regulates miRNAs controlling allergic inflammation. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00141.2017. PMID 28798252 DOI: 10.1152/Ajplung.00141.2017 |
0.423 |
|
| 2017 |
Yang J, Tian B, Sun H, Garofalo RP, Brasier AR. Epigenetic silencing of IRF1 dysregulates type III interferon responses to respiratory virus infection in epithelial to mesenchymal transition. Nature Microbiology. 2: 17086. PMID 28581456 DOI: 10.1038/Nmicrobiol.2017.86 |
0.388 |
|
| 2017 |
Chen J, Peters AM, Papke CL, Villamizar C, Ringuette LJ, Cao JM, Wang S, Ma S, Gong L, Byanova K, Xiong J, Zhu MX, Madonna R, Kee P, Geng YJ, ... Brasier A, et al. Loss of Smooth Muscle α-actin Leads to NF-κB-Dependent Increased Sensitivity to Angiontensin II in Smooth Muscle Cells and Aortic Enlargement. Circulation Research. PMID 28461455 DOI: 10.1161/Circresaha.117.310563 |
0.368 |
|
| 2017 |
Zhao Y, Jamaluddin M, Zhang Y, Sun H, Ivanciuc T, Garofalo RP, Brasier AR. Systematic Analysis of Cell-Type Differences in the Epithelial Secretome Reveals Insights into the Pathogenesis of Respiratory Syncytial Virus-Induced Lower Respiratory Tract Infections. Journal of Immunology (Baltimore, Md. : 1950). PMID 28258195 DOI: 10.4049/Jimmunol.1601291 |
0.387 |
|
| 2017 |
Yang J, Tian B, Brasier AR. Targeting Chromatin Remodeling in Inflammation and Fibrosis. Advances in Protein Chemistry and Structural Biology. 107: 1-36. PMID 28215221 DOI: 10.1016/Bs.Apcsb.2016.11.001 |
0.428 |
|
| 2017 |
Liu Z, Wang P, Chen H, Wold EA, Tian B, Brasier AR, Zhou J. Drug Discovery Targeting Bromodomain-Containing Protein 4 (BRD4). Journal of Medicinal Chemistry. PMID 28195723 DOI: 10.1021/Acs.Jmedchem.6B01761 |
0.366 |
|
| 2017 |
Ijaz T, Jamaluddin M, Zhao Y, Zhang Y, Jay J, Finnerty CC, Herndon DN, Tilton RG, Brasier AR. Coordinate activities of BRD4 and CDK9 in the transcriptional elongation complex are required for TGFβ-induced Nox4 expression and myofibroblast transdifferentiation. Cell Death & Disease. 8: e2606. PMID 28182006 DOI: 10.1038/Cddis.2016.434 |
0.4 |
|
| 2017 |
Hosoki K, Brasier AR, Kurosky A, Boldogh I, Sur S. Reply: Protease Plays a Role in Ragweed Pollen-Induced Neutrophil Recruitment and Epithelial Barrier Disruption. American Journal of Respiratory Cell and Molecular Biology. 56: 272-273. PMID 28145773 DOI: 10.1165/Rcmb.2016-0281Le |
0.321 |
|
| 2017 |
Tian B, Yang J, Zhao Y, Ivanciuc T, Sun H, Garofalo RP, Brasier AR. Bromodomain Containing 4 (BRD4) Couples NFκB/RelA With Airway Inflammation And The IRF-RIG-I Amplification Loop In Respiratory Syncytial Virus Infection. Journal of Virology. PMID 28077651 DOI: 10.1128/Jvi.00007-17 |
0.453 |
|
| 2017 |
Belanger KK, Tian B, Brasier AR, Ameredes BT. Inhibition of IL-6 Release in Vitro by in Vivo Administration of an IKK Inhibitor in Mice with Lung Fibrosis Induced by Poly I:C The Journal of Allergy and Clinical Immunology. 139. DOI: 10.1016/J.Jaci.2016.12.294 |
0.338 |
|
| 2016 |
Tian B, Patrikeev I, Ochoa L, Vargas G, Belanger KK, Litvinov J, Boldogh I, Ameredes BT, Motamedi M, Brasier AR. NFκB Mediates Mesenchymal Transition, Remodeling and Pulmonary Fibrosis in Response to Chronic Inflammation by Viral RNA Patterns. American Journal of Respiratory Cell and Molecular Biology. PMID 27911568 DOI: 10.1165/Rcmb.2016-0259Oc |
0.384 |
|
| 2016 |
Tian B, Zhao Y, Sun H, Zhang Y, Yang J, Brasier AR. BRD4 Mediates NFκB-dependent Epithelial-Mesenchymal Transition and Pulmonary Fibrosis via Transcriptional Elongation. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00224.2016. PMID 27793799 DOI: 10.1152/Ajplung.00224.2016 |
0.419 |
|
| 2016 |
Pan L, Zhu B, Hao W, Zeng X, Vlahopoulos SA, Hazra TK, Hegde ML, Radak Z, Bacsi A, Brasier AR, Ba X, Boldogh I. Oxidized Guanine Base Lesions Function in 8-Oxoguanine DNA Glycosylase1-Mediated Epigenetic Regulation of Nuclear Factor kappaB-Driven Gene Expression. The Journal of Biological Chemistry. PMID 27756845 DOI: 10.1074/Jbc.M116.751453 |
0.379 |
|
| 2016 |
Ijaz T, Wakamiya M, Sun H, Recinos A, Tilton RG, Brasier AR. Generation and characterization of a novel transgenic mouse harboring conditional nuclear factor-kappa B/RelA knockout alleles. Bmc Developmental Biology. 16: 32. PMID 27662828 DOI: 10.1186/S12861-016-0135-8 |
0.365 |
|
| 2016 |
Ijaz T, Tilton RG, Brasier AR. Cytokine amplification and macrophage effector functions in aortic inflammation and abdominal aortic aneurysm formation. Journal of Thoracic Disease. 8: E746-54. PMID 27619163 DOI: 10.21037/Jtd.2016.06.37 |
0.423 |
|
| 2016 |
Hosakote YM, Brasier AR, Casola A, Garofalo RP, Kurosky A. RSV Infection Triggers Epithelial HMGB1 Release as a Damage-Associated Molecular Pattern Promoting a Monocytic Inflammatory Response. Journal of Virology. PMID 27535058 DOI: 10.1128/Jvi.01279-16 |
0.36 |
|
| 2016 |
Zhao Y, Tian B, Sadygov RG, Zhang Y, Brasier AR. Integrative proteomic analysis reveals reprograming tumor necrosis factor signaling in epithelial mesenchymal transition. Journal of Proteomics. PMID 27461979 DOI: 10.1016/J.Jprot.2016.07.014 |
0.393 |
|
| 2016 |
Choudhary S, Boldogh I, Brasier AR. Inside-Out Signaling Pathways from Nuclear Reactive Oxygen Species Control Pulmonary Innate Immunity. Journal of Innate Immunity. PMID 26756522 DOI: 10.1159/000442254 |
0.389 |
|
| 2016 |
Belanger KK, Spear WC, Rolls BA, Miller S, Tian B, Vargas G, Motamedi M, Boldogh I, Brasier A, Ameredes BT. Modulation of IL-6 Release Subsequent to Airway Poly I:C Administration Journal of Allergy and Clinical Immunology. 137: AB111. DOI: 10.1016/J.Jaci.2015.12.487 |
0.321 |
|
| 2015 |
Hosoki K, Boldogh I, Leopoldo AA, Sun Q, Itazawa T, Hazra T, Brasier AR, Kurosky A, Sur S. Myeloid differentiation protein 2 facilitates pollen- and cat dander-induced innate and allergic airway inflammation. The Journal of Allergy and Clinical Immunology. PMID 26586036 DOI: 10.1016/J.Jaci.2015.09.036 |
0.406 |
|
| 2015 |
Zhao Y, Valbuena G, Walker DH, Gazi M, Hidalgo M, De Sousa R, Oteo JA, Goez Y, Brasier AR. Endothelial cell proteomic response to Rickettsia conorii infection reveals activation of the Jak-STAT-ISG15 pathway and reprogramming plasma membrane integrin/cadherin signaling. Molecular & Cellular Proteomics : McP. PMID 26560068 DOI: 10.1074/Mcp.M115.054361 |
0.384 |
|
| 2015 |
Yang J, Zhao Y, Kalita M, Li X, Jamaluddin M, Tian B, Edeh CB, Wiktorowicz JE, Kudlicki A, Brasier AR. Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases. Molecular & Cellular Proteomics : McP. 14: 2701-21. PMID 26209609 DOI: 10.1074/Mcp.M115.049221 |
0.351 |
|
| 2015 |
Aguilera-Aguirre L, Hosoki K, Bacsi A, Radák Z, Sur S, Hegde ML, Tian B, Saavedra-Molina A, Brasier AR, Ba X, Boldogh I. Whole transcriptome analysis reveals a role for OGG1-initiated DNA repair signaling in airway remodeling. Free Radical Biology & Medicine. 89: 20-33. PMID 26187872 DOI: 10.1016/J.Freeradbiomed.2015.07.007 |
0.37 |
|
| 2015 |
Tian B, Li X, Kalita M, Widen SG, Yang J, Bhavnani SK, Dang B, Kudlicki A, Sinha M, Kong F, Wood TG, Luxon BA, Brasier AR. Analysis of the TGFβ-induced program in primary airway epithelial cells shows essential role of NF-κB/RelA signaling network in type II epithelial mesenchymal transition. Bmc Genomics. 16: 529. PMID 26187636 DOI: 10.1186/S12864-015-1707-X |
0.448 |
|
| 2015 |
Hosoki K, Aguilera-Aguirre L, Brasier AR, Kurosky A, Boldogh I, Sur S. Pollen-induced Innate Recruitment of Neutrophils Facilitates Induction of Allergic Sensitization and Airway Inflammation. American Journal of Respiratory Cell and Molecular Biology. PMID 26086549 DOI: 10.1165/Rcmb.2015-0044Oc |
0.362 |
|
| 2015 |
Komaravelli N, Tian B, Ivanciuc T, Mautemps N, Brasier AR, Garofalo RP, Casola A. Respiratory syncytial virus infection downregulates antioxidant enzyme expression by TRIGGERING deacetylation-proteasomal degradation of NRF2. Free Radical Biology & Medicine. PMID 26073125 DOI: 10.1016/J.Freeradbiomed.2015.05.043 |
0.379 |
|
| 2015 |
Desai P, Yang J, Tian B, Sun H, Kalita M, Ju H, Paulucci-Holthauzen A, Zhao Y, Brasier AR, Sadygov RG. Mixed-effects model of epithelial-mesenchymal transition reveals rewiring of signaling networks. Cellular Signalling. 27: 1413-25. PMID 25862520 DOI: 10.1016/J.Cellsig.2015.03.024 |
0.37 |
|
| 2015 |
Li X, Zhu M, Brasier AR, Kudlicki AS. Inferring genome-wide functional modulatory network: a case study on NF-κB/RelA transcription factor. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 22: 300-12. PMID 25844669 DOI: 10.1089/Cmb.2014.0299 |
0.369 |
|
| 2015 |
Willis R, Gonzalez EB, Brasier AR. The journey of antiphospholipid antibodies from cellular activation to antiphospholipid syndrome. Current Rheumatology Reports. 17: 16. PMID 25761923 DOI: 10.1007/S11926-014-0485-9 |
0.305 |
|
| 2015 |
Aguilera-Aguirre L, Hosoki K, Bacsi A, Radák Z, Wood TG, Widen SG, Sur S, Ameredes BT, Saavedra-Molina A, Brasier AR, Ba X, Boldogh I. Whole transcriptome analysis reveals an 8-oxoguanine DNA glycosylase-1-driven DNA repair-dependent gene expression linked to essential biological processes. Free Radical Biology & Medicine. 81: 107-18. PMID 25614460 DOI: 10.1016/J.Freeradbiomed.2015.01.004 |
0.342 |
|
| 2015 |
Fang L, Choudhary S, Tian B, Boldogh I, Yang C, Ivanciuc T, Ma Y, Garofalo RP, Brasier AR. Ataxia telangiectasia mutated kinase mediates NF-κB serine 276 phosphorylation and interferon expression via the IRF7-RIG-I amplification loop in paramyxovirus infection. Journal of Virology. 89: 2628-42. PMID 25520509 DOI: 10.1128/Jvi.02458-14 |
0.44 |
|
| 2014 |
Aguilera-Aguirre L, Bacsi A, Radak Z, Hazra TK, Mitra S, Sur S, Brasier AR, Ba X, Boldogh I. Innate inflammation induced by the 8-oxoguanine DNA glycosylase-1-KRAS-NF-κB pathway. Journal of Immunology (Baltimore, Md. : 1950). 193: 4643-53. PMID 25267977 DOI: 10.4049/Jimmunol.1401625 |
0.398 |
|
| 2014 |
Ijaz T, Pazdrak K, Kalita M, Konig R, Choudhary S, Tian B, Boldogh I, Brasier AR. Systems biology approaches to understanding Epithelial Mesenchymal Transition (EMT) in mucosal remodeling and signaling in asthma. The World Allergy Organization Journal. 7: 13. PMID 24982697 DOI: 10.1186/1939-4551-7-13 |
0.344 |
|
| 2014 |
Fang L, Choudhary S, Zhao Y, Edeh CB, Yang C, Boldogh I, Brasier AR. ATM regulates NF-κB-dependent immediate-early genes via RelA Ser 276 phosphorylation coupled to CDK9 promoter recruitment. Nucleic Acids Research. 42: 8416-32. PMID 24957606 DOI: 10.1093/Nar/Gku529 |
0.407 |
|
| 2014 |
Kolokoltsova OA, Grant AM, Huang C, Smith JK, Poussard AL, Tian B, Brasier AR, Peters CJ, Tseng CT, de la Torre JC, Paessler S. RIG-I enhanced interferon independent apoptosis upon Junin virus infection. Plos One. 9: e99610. PMID 24918927 DOI: 10.1371/Journal.Pone.0099610 |
0.314 |
|
| 2014 |
Bertolusso R, Tian B, Zhao Y, Vergara L, Sabree A, Iwanaszko M, Lipniacki T, Brasier AR, Kimmel M. Dynamic cross talk model of the epithelial innate immune response to double-stranded RNA stimulation: coordinated dynamics emerging from cell-level noise. Plos One. 9: e93396. PMID 24710104 DOI: 10.1371/Journal.Pone.0093396 |
0.341 |
|
| 2014 |
Luo J, Hosoki K, Bacsi A, Radak Z, Hegde ML, Sur S, Hazra TK, Brasier AR, Ba X, Boldogh I. 8-Oxoguanine DNA glycosylase-1-mediated DNA repair is associated with Rho GTPase activation and α-smooth muscle actin polymerization. Free Radical Biology & Medicine. 73: 430-8. PMID 24681335 DOI: 10.1016/J.Freeradbiomed.2014.03.030 |
0.337 |
|
| 2014 |
Ray S, Zhao Y, Jamaluddin M, Edeh CB, Lee C, Brasier AR. Inducible STAT3 NH2 terminal mono-ubiquitination promotes BRD4 complex formation to regulate apoptosis. Cellular Signalling. 26: 1445-55. PMID 24657799 DOI: 10.1016/J.Cellsig.2014.03.007 |
0.434 |
|
| 2014 |
Li X, Zhao Y, Tian B, Jamaluddin M, Mitra A, Yang J, Rowicka M, Brasier AR, Kudlicki A. Modulation of gene expression regulated by the transcription factor NF-κB/RelA. The Journal of Biological Chemistry. 289: 11927-44. PMID 24523406 DOI: 10.1074/Jbc.M113.539965 |
0.34 |
|
| 2014 |
Ba X, Bacsi A, Luo J, Aguilera-Aguirre L, Zeng X, Radak Z, Brasier AR, Boldogh I. 8-oxoguanine DNA glycosylase-1 augments proinflammatory gene expression by facilitating the recruitment of site-specific transcription factors. Journal of Immunology (Baltimore, Md. : 1950). 192: 2384-94. PMID 24489103 DOI: 10.4049/Jimmunol.1302472 |
0.42 |
|
| 2014 |
Ju X, Ijaz T, Sun H, Lejeune W, Vargas G, Shilagard T, Recinos A, Milewicz DM, Brasier AR, Tilton RG. IL-6 regulates extracellular matrix remodeling associated with aortic dilation in a fibrillin-1 hypomorphic mgR/mgR mouse model of severe Marfan syndrome. Journal of the American Heart Association. 3: e000476. PMID 24449804 DOI: 10.1161/Jaha.113.000476 |
0.619 |
|
| 2014 |
Brasier AR, Zhao Y. Measurement of the innate immune response in the airway. Advances in Experimental Medicine and Biology. 795: 233-54. PMID 24162913 DOI: 10.1007/978-1-4614-8603-9_15 |
0.432 |
|
| 2014 |
Beswick EJ, Lina TT, Brasier AR, Jemal H, Powell DW, Reyes VE, Pinchuk IV. 23 MyD88-Dependent Signaling in Fibroblasts: Critical Role in the Colonic Mucosal Tolerance Gastroenterology. 146: S-7. DOI: 10.1016/S0016-5085(14)60023-8 |
0.307 |
|
| 2013 |
Kalita M, Tian B, Gao B, Choudhary S, Wood TG, Carmical JR, Boldogh I, Mitra S, Minna JD, Brasier AR. Systems approaches to modeling chronic mucosal inflammation. Biomed Research International. 2013: 505864. PMID 24228254 DOI: 10.1155/2013/505864 |
0.409 |
|
| 2013 |
Brasier AR. Identification of innate immune response endotypes in asthma: implications for personalized medicine. Current Allergy and Asthma Reports. 13: 462-8. PMID 23793609 DOI: 10.1007/S11882-013-0363-Y |
0.322 |
|
| 2013 |
Yang J, Mitra A, Dojer N, Fu S, Rowicka M, Brasier AR. A probabilistic approach to learn chromatin architecture and accurate inference of the NF-κB/RelA regulatory network using ChIP-Seq. Nucleic Acids Research. 41: 7240-59. PMID 23771139 DOI: 10.1093/Nar/Gkt493 |
0.345 |
|
| 2013 |
Drummond MJ, Timmerman KL, Markofski MM, Walker DK, Dickinson JM, Jamaluddin M, Brasier AR, Rasmussen BB, Volpi E. Short-term bed rest increases TLR4 and IL-6 expression in skeletal muscle of older adults. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 305: R216-23. PMID 23761639 DOI: 10.1152/Ajpregu.00072.2013 |
0.323 |
|
| 2013 |
Ju X, Ijaz T, Sun H, Ray S, Lejeune W, Lee C, Recinos A, Guo DC, Milewicz DM, Tilton RG, Brasier AR. Interleukin-6-signal transducer and activator of transcription-3 signaling mediates aortic dissections induced by angiotensin II via the T-helper lymphocyte 17-interleukin 17 axis in C57BL/6 mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1612-21. PMID 23685554 DOI: 10.1161/Atvbaha.112.301049 |
0.656 |
|
| 2013 |
Tian B, Zhao Y, Kalita M, Edeh CB, Paessler S, Casola A, Teng MN, Garofalo RP, Brasier AR. CDK9-dependent transcriptional elongation in the innate interferon-stimulated gene response to respiratory syncytial virus infection in airway epithelial cells. Journal of Virology. 87: 7075-92. PMID 23596302 DOI: 10.1128/Jvi.03399-12 |
0.423 |
|
| 2013 |
Choudhary S, Kalita M, Fang L, Patel KV, Tian B, Zhao Y, Edeh CB, Brasier AR. Inducible tumor necrosis factor (TNF) receptor-associated factor-1 expression couples the canonical to the non-canonical NF-κB pathway in TNF stimulation. The Journal of Biological Chemistry. 288: 14612-23. PMID 23543740 DOI: 10.1074/Jbc.M113.464081 |
0.416 |
|
| 2013 |
Zhao Y, Tian B, Edeh CB, Brasier AR. Quantitation of the dynamic profiles of the innate immune response using multiplex selected reaction monitoring-mass spectrometry. Molecular & Cellular Proteomics : McP. 12: 1513-29. PMID 23418394 DOI: 10.1074/Mcp.M112.023465 |
0.441 |
|
| 2013 |
Zhao Y, Brasier AR. Applications of selected reaction monitoring (SRM)-mass spectrometry (MS) for quantitative measurement of signaling pathways. Methods (San Diego, Calif.). 61: 313-22. PMID 23410677 DOI: 10.1016/J.Ymeth.2013.02.001 |
0.31 |
|
| 2013 |
Ray S, Ju X, Sun H, Finnerty CC, Herndon DN, Brasier AR. The IL-6 trans-signaling-STAT3 pathway mediates ECM and cellular proliferation in fibroblasts from hypertrophic scar. The Journal of Investigative Dermatology. 133: 1212-20. PMID 23303450 DOI: 10.1038/Jid.2012.499 |
0.658 |
|
| 2013 |
Espejo R, Jeng Y, Johnson C, Carmical R, Brasier A, Chao C, Sastry SK. Abstract LB-282: Loss of PTP-PEST promotes tumor invasion, apoptosis resistance and activation of STAT3 in metastatic colon cancer. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-282 |
0.333 |
|
| 2012 |
Huang C, Kolokoltsova OA, Yun NE, Seregin AV, Poussard AL, Walker AG, Brasier AR, Zhao Y, Tian B, de la Torre JC, Paessler S. JunÃn virus infection activates the type I interferon pathway in a RIG-I-dependent manner. Plos Neglected Tropical Diseases. 6: e1659. PMID 22629479 DOI: 10.1371/Journal.Pntd.0001659 |
0.348 |
|
| 2012 |
Iwanaszko M, Brasier AR, Kimmel M. The dependence of expression of NF-κB-dependent genes: statistics and evolutionary conservation of control sequences in the promoter and in the 3' UTR. Bmc Genomics. 13: 182. PMID 22577947 DOI: 10.1186/1471-2164-13-182 |
0.352 |
|
| 2012 |
Murai H, Qi H, Choudhury B, Wild J, Dharajiya N, Vaidya S, Kalita A, Bacsi A, Corry D, Kurosky A, Brasier A, Boldogh I, Sur S. Alternaria-induced release of IL-18 from damaged airway epithelial cells: an NF-κB dependent mechanism of Th2 differentiation? Plos One. 7: e30280. PMID 22347372 DOI: 10.1371/Journal.Pone.0030280 |
0.397 |
|
| 2012 |
Brasier AR, Ju H, Garcia J, Spratt HM, Victor SS, Forshey BM, Halsey ES, Comach G, Sierra G, Blair PJ, Rocha C, Morrison AC, Scott TW, Bazan I, Kochel TJ, et al. A three-component biomarker panel for prediction of dengue hemorrhagic fever American Journal of Tropical Medicine and Hygiene. 86: 341-348. PMID 22302872 DOI: 10.4269/Ajtmh.2012.11-0469 |
0.315 |
|
| 2012 |
Tian B, Yang J, Brasier AR. Two-step cross-linking for analysis of protein-chromatin interactions. Methods in Molecular Biology (Clifton, N.J.). 809: 105-20. PMID 22113271 DOI: 10.1007/978-1-61779-376-9_7 |
0.348 |
|
| 2011 |
Choudhary S, Rosenblatt KP, Fang L, Tian B, Wu ZH, Brasier AR. High throughput short interfering RNA (siRNA) screening of the human kinome identifies novel kinases controlling the canonical nuclear factor-κB (NF-κB) activation pathway. The Journal of Biological Chemistry. 286: 37187-95. PMID 21900239 DOI: 10.1074/Jbc.M111.224923 |
0.429 |
|
| 2011 |
Brasier AR, Tian B, Jamaluddin M, Kalita MK, Garofalo RP, Lu M. RelA Ser276 phosphorylation-coupled Lys310 acetylation controls transcriptional elongation of inflammatory cytokines in respiratory syncytial virus infection. Journal of Virology. 85: 11752-69. PMID 21900162 DOI: 10.1128/Jvi.05360-11 |
0.465 |
|
| 2011 |
Kalita MK, Sargsyan K, Tian B, Paulucci-Holthauzen A, Najm HN, Debusschere BJ, Brasier AR. Sources of cell-to-cell variability in canonical nuclear factor-κB (NF-κB) signaling pathway inferred from single cell dynamic images. The Journal of Biological Chemistry. 286: 37741-57. PMID 21868381 DOI: 10.1074/Jbc.M111.280925 |
0.36 |
|
| 2011 |
Zhao Y, Widen SG, Jamaluddin M, Tian B, Wood TG, Edeh CB, Brasier AR. Quantification of activated NF-kappaB/RelA complexes using ssDNA aptamer affinity-stable isotope dilution-selected reaction monitoring-mass spectrometry. Molecular & Cellular Proteomics : McP. 10: M111.008771. PMID 21502374 DOI: 10.1074/Mcp.M111.008771 |
0.38 |
|
| 2011 |
Tieu BC, Ju X, Lee C, Sun H, Lejeune W, Recinos A, Brasier AR, Tilton RG. Aortic adventitial fibroblasts participate in angiotensin-induced vascular wall inflammation and remodeling. Journal of Vascular Research. 48: 261-72. PMID 21099231 DOI: 10.1159/000320358 |
0.758 |
|
| 2010 |
Bao X, Indukuri H, Liu T, Liao SL, Tian B, Brasier AR, Garofalo RP, Casola A. IKKε modulates RSV-induced NF-κB-dependent gene transcription. Virology. 408: 224-31. PMID 20961594 DOI: 10.1016/J.Virol.2010.09.016 |
0.443 |
|
| 2010 |
Jamaluddin M, Wiktorowicz JE, Soman KV, Boldogh I, Forbus JD, Spratt H, Garofalo RP, Brasier AR. Role of peroxiredoxin 1 and peroxiredoxin 4 in protection of respiratory syncytial virus-induced cysteinyl oxidation of nuclear cytoskeletal proteins. Journal of Virology. 84: 9533-45. PMID 20610706 DOI: 10.1128/Jvi.01005-10 |
0.358 |
|
| 2010 |
Brasier AR. The nuclear factor-kappaB-interleukin-6 signalling pathway mediating vascular inflammation. Cardiovascular Research. 86: 211-8. PMID 20202975 DOI: 10.1093/Cvr/Cvq076 |
0.465 |
|
| 2010 |
Wang N, Dong Q, Li J, Jangra RK, Fan M, Brasier AR, Lemon SM, Pfeffer LM, Li K. Viral induction of the zinc finger antiviral protein is IRF3-dependent but NF-kappaB-independent. The Journal of Biological Chemistry. 285: 6080-90. PMID 20048147 DOI: 10.1074/Jbc.M109.054486 |
0.42 |
|
| 2010 |
Ray S, Lee C, Hou T, Bhakat KK, Brasier AR. Regulation of signal transducer and activator of transcription 3 enhanceosome formation by apurinic/apyrimidinic endonuclease 1 in hepatic acute phase response. Molecular Endocrinology (Baltimore, Md.). 24: 391-401. PMID 20032196 DOI: 10.1210/Me.2009-0319 |
0.475 |
|
| 2009 |
Liu P, Lu M, Tian B, Li K, Garofalo RP, Prusak D, Wood TG, Brasier AR. Expression of an IKKgamma splice variant determines IRF3 and canonical NF-kappaB pathway utilization in ssRNA virus infection. Plos One. 4: e8079. PMID 19956647 DOI: 10.1371/Journal.Pone.0008079 |
0.396 |
|
| 2009 |
Tieu BC, Lee C, Sun H, Lejeune W, Recinos A, Ju X, Spratt H, Guo DC, Milewicz D, Tilton RG, Brasier AR. An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice. The Journal of Clinical Investigation. 119: 3637-51. PMID 19920349 DOI: 10.1172/Jci38308 |
0.78 |
|
| 2009 |
Jamaluddin M, Tian B, Boldogh I, Garofalo RP, Brasier AR. Respiratory syncytial virus infection induces a reactive oxygen species-MSK1-phospho-Ser-276 RelA pathway required for cytokine expression. Journal of Virology. 83: 10605-15. PMID 19706715 DOI: 10.1128/Jvi.01090-09 |
0.447 |
|
| 2009 |
Patel JA, Nair S, Grady J, Revai K, Victor S, Brasier AR, Chonmaitree T. Systemic cytokine response profiles associated with respiratory virus-induced acute otitis media. The Pediatric Infectious Disease Journal. 28: 407-11. PMID 19352211 DOI: 10.1097/Inf.0B013E318194B7C6 |
0.369 |
|
| 2008 |
Hou T, Tieu BC, Ray S, Recinos Iii A, Cui R, Tilton RG, Brasier AR. Roles of IL-6-gp130 Signaling in Vascular Inflammation. Current Cardiology Reviews. 4: 179-92. PMID 19936194 DOI: 10.2174/157340308785160570 |
0.79 |
|
| 2008 |
Hou T, Ray S, Lee C, Brasier AR. The STAT3 NH2-terminal domain stabilizes enhanceosome assembly by interacting with the p300 bromodomain. The Journal of Biological Chemistry. 283: 30725-34. PMID 18782771 DOI: 10.1074/Jbc.M805941200 |
0.355 |
|
| 2008 |
Brasier AR. Expanding role of cyclin dependent kinases in cytokine inducible gene expression. Cell Cycle (Georgetown, Tex.). 7: 2661-6. PMID 18728388 DOI: 10.4161/Cc.7.17.6594 |
0.447 |
|
| 2008 |
Smieja J, Jamaluddin M, Brasier AR, Kimmel M. Model-based analysis of interferon-beta induced signaling pathway. Bioinformatics (Oxford, England). 24: 2363-9. PMID 18713791 DOI: 10.1093/Bioinformatics/Btn400 |
0.338 |
|
| 2008 |
Ray S, Lee C, Hou T, Boldogh I, Brasier AR. Requirement of histone deacetylase1 (HDAC1) in signal transducer and activator of transcription 3 (STAT3) nucleocytoplasmic distribution. Nucleic Acids Research. 36: 4510-20. PMID 18611949 DOI: 10.1093/Nar/Gkn419 |
0.43 |
|
| 2008 |
Liu P, Li K, Garofalo RP, Brasier AR. Respiratory syncytial virus induces RelA release from cytoplasmic 100-kDa NF-kappa B2 complexes via a novel retinoic acid-inducible gene-I{middle dot}NF- kappa B-inducing kinase signaling pathway. The Journal of Biological Chemistry. 283: 23169-78. PMID 18550535 DOI: 10.1074/Jbc.M802729200 |
0.427 |
|
| 2008 |
Nowak DE, Tian B, Jamaluddin M, Boldogh I, Vergara LA, Choudhary S, Brasier AR. RelA Ser276 phosphorylation is required for activation of a subset of NF-κB-dependent genes by recruiting cyclin-dependent kinase 9/cyclin t1 complexes Molecular and Cellular Biology. 28: 3623-3638. PMID 18362169 DOI: 10.1128/Mcb.01152-07 |
0.459 |
|
| 2008 |
Pazdrak K, Young TW, Stafford S, Olszewska-Pazdrak B, Straub C, Starosta V, Brasier A, Kurosky A. Cross-talk between ICAM-1 and granulocyte-macrophage colony-stimulating factor receptor signaling modulates eosinophil survival and activation. Journal of Immunology (Baltimore, Md. : 1950). 180: 4182-90. PMID 18322230 DOI: 10.4049/Jimmunol.180.6.4182 |
0.406 |
|
| 2008 |
Brasier AR, Victor S, Boetticher G, Ju H, Lee C, Bleecker ER, Castro M, Busse WW, Calhoun WJ. Molecular phenotyping of severe asthma using pattern recognition of bronchoalveolar lavage-derived cytokines. The Journal of Allergy and Clinical Immunology. 121: 30-37.e6. PMID 18206505 DOI: 10.1016/J.Jaci.2007.10.015 |
0.344 |
|
| 2007 |
Hou T, Ray S, Brasier AR. The functional role of an interleukin 6-inducible CDK9.STAT3 complex in human gamma-fibrinogen gene expression. The Journal of Biological Chemistry. 282: 37091-102. PMID 17956865 DOI: 10.1074/Jbc.M706458200 |
0.461 |
|
| 2007 |
Lipniacki T, Puszynski K, Paszek P, Brasier AR, Kimmel M. Single TNFalpha trimers mediating NF-kappaB activation: stochastic robustness of NF-kappaB signaling. Bmc Bioinformatics. 8: 376. PMID 17925009 DOI: 10.1186/1471-2105-8-376 |
0.401 |
|
| 2007 |
Pannu H, Tran-Fadulu V, Papke CL, Scherer S, Liu Y, Presley C, Guo D, Estrera AL, Safi HJ, Brasier AR, Vick GW, Marian AJ, Raman CS, Buja LM, Milewicz DM. MYH11 mutations result in a distinct vascular pathology driven by insulin-like growth factor 1 and angiotensin II. Human Molecular Genetics. 16: 2453-62. PMID 17666408 DOI: 10.1093/Hmg/Ddm201 |
0.331 |
|
| 2007 |
Choudhary S, Lu M, Cui R, Brasier AR. Involvement of a novel Rac/RhoA guanosine triphosphatase-nuclear factor-kappaB inducing kinase signaling pathway mediating angiotensin II-induced RelA transactivation. Molecular Endocrinology (Baltimore, Md.). 21: 2203-17. PMID 17595324 DOI: 10.1210/Me.2006-0465 |
0.447 |
|
| 2007 |
Jamaluddin M, Wang S, Boldogh I, Tian B, Brasier AR. TNF-alpha-induced NF-kappaB/RelA Ser(276) phosphorylation and enhanceosome formation is mediated by an ROS-dependent PKAc pathway. Cellular Signalling. 19: 1419-33. PMID 17317104 DOI: 10.1016/J.Cellsig.2007.01.020 |
0.424 |
|
| 2007 |
Recinos A, LeJeune WS, Sun H, Lee CY, Tieu BC, Lu M, Hou T, Boldogh I, Tilton RG, Brasier AR. Angiotensin II induces IL-6 expression and the Jak-STAT3 pathway in aortic adventitia of LDL receptor-deficient mice. Atherosclerosis. 194: 125-33. PMID 17109863 DOI: 10.1016/J.Atherosclerosis.2006.10.013 |
0.796 |
|
| 2007 |
Liu P, Jamaluddin M, Li K, Garofalo RP, Casola A, Brasier AR. Retinoic acid-inducible gene I mediates early antiviral response and Toll-like receptor 3 expression in respiratory syncytial virus-infected airway epithelial cells. Journal of Virology. 81: 1401-11. PMID 17108032 DOI: 10.1128/Jvi.01740-06 |
0.436 |
|
| 2007 |
Wagoner J, Austin M, Green J, Imaizumi T, Casola A, Brasier A, Khabar KS, Wakita T, Gale M, Polyak SJ. Regulation of CXCL-8 (interleukin-8) induction by double-stranded RNA signaling pathways during hepatitis C virus infection. Journal of Virology. 81: 309-18. PMID 17035306 DOI: 10.1128/Jvi.01411-06 |
0.397 |
|
| 2006 |
Cui R, Tieu B, Recinos A, Tilton RG, Brasier AR. RhoA mediates angiotensin II-induced phospho-Ser536 nuclear factor kappaB/RelA subunit exchange on the interleukin-6 promoter in VSMCs. Circulation Research. 99: 723-30. PMID 16960103 DOI: 10.1161/01.Res.0000244015.10655.3F |
0.807 |
|
| 2006 |
Indukuri H, Castro SM, Liao SM, Feeney LA, Dorsch M, Coyle AJ, Garofalo RP, Brasier AR, Casola A. Ikkepsilon regulates viral-induced interferon regulatory factor-3 activation via a redox-sensitive pathway Virology. 353: 155-165. PMID 16806387 DOI: 10.1016/J.Virol.2006.05.022 |
0.454 |
|
| 2006 |
Starkey JM, Haidacher SJ, LeJeune WS, Zhang X, Tieu BC, Choudhary S, Brasier AR, Denner LA, Tilton RG. Diabetes-induced activation of canonical and noncanonical nuclear factor-kappaB pathways in renal cortex. Diabetes. 55: 1252-9. PMID 16644679 DOI: 10.2337/Db05-1554 |
0.769 |
|
| 2006 |
Hai T, Yeung ML, Wood TG, Wei Y, Yamaoka S, Gatalica Z, Jeang KT, Brasier AR. An alternative splice product of IkappaB kinase (IKKgamma), IKKgamma-delta, differentially mediates cytokine and human T-cell leukemia virus type 1 tax-induced NF-kappaB activation. Journal of Virology. 80: 4227-41. PMID 16611882 DOI: 10.1128/Jvi.80.9.4227-4241.2006 |
0.439 |
|
| 2006 |
Forbus J, Spratt H, Wiktorowicz J, Wu Z, Boldogh I, Denner L, Kurosky A, Brasier RC, Luxon B, Brasier AR. Functional analysis of the nuclear proteome of human A549 alveolar epithelial cells by HPLC-high resolution 2-D gel electrophoresis. Proteomics. 6: 2656-72. PMID 16586437 DOI: 10.1002/Pmic.200500652 |
0.352 |
|
| 2006 |
O'Donnell SM, Holm GH, Pierce JM, Tian B, Watson MJ, Chari RS, Ballard DW, Brasier AR, Dermody TS. Identification of an NF-kappaB-dependent gene network in cells infected by mammalian reovirus. Journal of Virology. 80: 1077-86. PMID 16414985 DOI: 10.1128/Jvi.80.3.1077-1086.2006 |
0.415 |
|
| 2006 |
Lipniacki T, Paszek P, Brasier AR, Luxon BA, Kimmel M. Stochastic regulation in early immune response. Biophysical Journal. 90: 725-42. PMID 16284261 DOI: 10.1529/Biophysj.104.056754 |
0.386 |
|
| 2006 |
Lipniacki T, Paszek P, Marciniak-Czochra A, Brasier AR, Kimmel M. Transcriptional stochasticity in gene expression. Journal of Theoretical Biology. 238: 348-67. PMID 16039671 DOI: 10.1016/J.Jtbi.2005.05.032 |
0.336 |
|
| 2006 |
Pazdrak K, Young TW, Wiktorowicz J, Brasier AR, Kurosky A. Involvement of Adhesion Signaling in GM-CSF-induced Activation of Eosinophils; Evidence of Shp2- Slp76-mediated Cross-talk Between the c Receptor and ICAM-1 The Journal of Allergy and Clinical Immunology. 117. DOI: 10.1016/J.Jaci.2005.12.572 |
0.335 |
|
| 2005 |
Nowak DE, Tian B, Brasier AR. Two-step cross-linking method for identification of NF-κB gene network by chromatin immunoprecipitation Biotechniques. 39: 715-724. PMID 16315372 DOI: 10.2144/000112014 |
0.374 |
|
| 2005 |
Jamaluddin M, Choudhary S, Wang S, Casola A, Huda R, Garofalo RP, Ray S, Brasier AR. Respiratory syncytial virus-inducible BCL-3 expression antagonizes the STAT/IRF and NF-kappaB signaling pathways by inducing histone deacetylase 1 recruitment to the interleukin-8 promoter. Journal of Virology. 79: 15302-13. PMID 16306601 DOI: 10.1128/Jvi.79.24.15302-15313.2005 |
0.478 |
|
| 2005 |
Ray S, Boldogh I, Brasier AR. STAT3 NH2-terminal acetylation is activated by the hepatic acute-phase response and required for IL-6 induction of angiotensinogen. Gastroenterology. 129: 1616-32. PMID 16285960 DOI: 10.1053/J.Gastro.2005.07.055 |
0.437 |
|
| 2005 |
Tian B, Nowak DE, Brasier AR. A TNF-induced gene expression program under oscillatory NF-κB control Bmc Genomics. 6. PMID 16191192 DOI: 10.1186/1471-2164-6-137 |
0.419 |
|
| 2005 |
Choudhary S, Boldogh S, Garofalo R, Jamaluddin M, Brasier AR. Respiratory Syncytial Virus Influences NF-κB-Dependent Gene Expression through a Novel Pathway Involving MAP3K14/NIK Expression and Nuclear Complex Formation with NF-κB2 Journal of Virology. 79: 8948-8959. PMID 15994789 DOI: 10.1128/Jvi.79.14.8948-8959.2005 |
0.462 |
|
| 2005 |
Tian B, Nowak DE, Jamaluddin M, Wang S, Brasier AR. Identification of direct genomic targets downstream of the nuclear factor-κB transcription factor mediating tumor necrosis factor signaling Journal of Biological Chemistry. 280: 17435-17448. PMID 15722553 DOI: 10.1074/Jbc.M500437200 |
0.45 |
|
| 2005 |
Paszek P, Lipniacki T, Brasier AR, Tian B, Nowak DE, Kimmel M. Stochastic effects of multiple regulators on expression profiles in eukaryotes. Journal of Theoretical Biology. 233: 423-33. PMID 15652150 DOI: 10.1016/J.Jtbi.2004.10.023 |
0.374 |
|
| 2004 |
Shimotake TK, Izhar FM, Rumilla K, Li J, Tan A, Page K, Brasier AR, Schreiber MD, Hershenson MB. Interleukin (IL)-1 beta in tracheal aspirates from premature infants induces airway epithelial cell IL-8 expression via an NF-kappa B dependent pathway. Pediatric Research. 56: 907-13. PMID 15496610 DOI: 10.1203/01.Pdr.0000145274.47221.10 |
0.402 |
|
| 2004 |
Brasier AR, Spratt H, Wu Z, Boldogh I, Zhang Y, Garofalo RP, Casola A, Pashmi J, Haag A, Luxon B, Kurosky A. Nuclear heat shock response and novel nuclear domain 10 reorganization in respiratory syncytial virus-infected a549 cells identified by high-resolution two-dimensional gel electrophoresis. Journal of Virology. 78: 11461-76. PMID 15479789 DOI: 10.1128/Jvi.78.21.11461-11476.2004 |
0.338 |
|
| 2004 |
Ray S, Lu Y, Kaufmann SH, Gustafson WC, Karp JE, Boldogh I, Fields AP, Brasier AR. Genomic mechanisms of p210BCR-ABL signaling: induction of heat shock protein 70 through the GATA response element confers resistance to paclitaxel-induced apoptosis. The Journal of Biological Chemistry. 279: 35604-15. PMID 15155749 DOI: 10.1074/Jbc.M401851200 |
0.373 |
|
| 2004 |
Yamaoka Y, Kudo T, Lu H, Casola A, Brasier AR, Graham DY. Role of interferon-stimulated responsive element-like element in interleukin-8 promoter in Helicobacter pylori infection. Gastroenterology. 126: 1030-43. PMID 15057743 DOI: 10.1053/J.Gastro.2003.12.048 |
0.378 |
|
| 2004 |
Haeberle HA, Casola A, Gatalica Z, Petronella S, Dieterich HJ, Ernst PB, Brasier AR, Garofalo RP. IkappaB kinase is a critical regulator of chemokine expression and lung inflammation in respiratory syncytial virus infection. Journal of Virology. 78: 2232-41. PMID 14963119 DOI: 10.1128/Jvi.78.5.2232-2241.2004 |
0.416 |
|
| 2004 |
Gustafson WC, Ray S, Jamieson L, Thompson EA, Brasier AR, Fields AP. Bcr-Abl regulates protein kinase Ciota (PKCiota) transcription via an Elk1 site in the PKCiota promoter. The Journal of Biological Chemistry. 279: 9400-8. PMID 14670960 DOI: 10.1074/Jbc.M312840200 |
0.396 |
|
| 2004 |
Liu T, Castro S, Brasier AR, Jamaluddin M, Garofalo RP, Casola A. Reactive oxygen species mediate virus-induced STAT activation: Role of tyrosine phosphatases Journal of Biological Chemistry. 279: 2461-2469. PMID 14578356 DOI: 10.1074/Jbc.M307251200 |
0.437 |
|
| 2003 |
Tian B, Brasier AR. Identification of a nuclear factor kappa B-dependent gene network. Recent Progress in Hormone Research. 58: 95-130. PMID 12795416 DOI: 10.1210/Rp.58.1.95 |
0.377 |
|
| 2003 |
Page K, Li J, Zhou L, Iasvovskaia S, Corbit KC, Soh JW, Weinstein IB, Brasier AR, Lin A, Hershenson MB, Iasvoyskaia S. Regulation of airway epithelial cell NF-kappa B-dependent gene expression by protein kinase C delta. Journal of Immunology (Baltimore, Md. : 1950). 170: 5681-9. PMID 12759450 DOI: 10.4049/Jimmunol.170.11.5681 |
0.461 |
|
| 2003 |
Zhang Y, Jamaluddin M, Wang S, Tian B, Garofalo RP, Casola A, Brasier AR. Ribavirin treatment up-regulates antiviral gene expression via the interferon-stimulated response element in respiratory syncytial virus-infected epithelial cells. Journal of Virology. 77: 5933-47. PMID 12719586 DOI: 10.1128/Jvi.77.10.5933-5947.2003 |
0.41 |
|
| 2003 |
Yamaoka Y, Kudo T, Lu H, Hwang I, Brasier AR, Graham DY. Role of a novel response element, interferon-stimulated responsive element-like element, in Helicobacter pylori OipA-induced interleukin-8 gene expression Gastroenterology. 124: A44. DOI: 10.1016/S0016-5085(03)80215-9 |
0.405 |
|
| 2002 |
Haeberle HA, Takizawa R, Casola A, Brasier AR, Dieterich HJ, Van Rooijen N, Gatalica Z, Garofalo RP. Respiratory syncytial virus-induced activation of nuclear factor-kappaB in the lung involves alveolar macrophages and toll-like receptor 4-dependent pathways. The Journal of Infectious Diseases. 186: 1199-206. PMID 12402188 DOI: 10.1086/344644 |
0.418 |
|
| 2002 |
Casola A, Henderson A, Liu T, Garofalo RP, Brasier AR. Regulation of RANTES promoter activation in alveolar epithelial cells after cytokine stimulation American Journal of Physiology-Lung Cellular and Molecular Physiology. 283. PMID 12388374 DOI: 10.1152/Ajplung.00162.2002 |
0.362 |
|
| 2002 |
Li J, Kartha S, Iasvovskaia S, Tan A, Bhat RK, Manaligod JM, Page K, Brasier AR, Hershenson MB. Regulation of human airway epithelial cell IL-8 expression by MAP kinases. American Journal of Physiology. Lung Cellular and Molecular Physiology. 283: L690-9. PMID 12225945 DOI: 10.1152/Ajplung.00060.2002 |
0.436 |
|
| 2002 |
Brasier AR, Recinos A, Eledrisi MS. Vascular Inflammation and the Renin-Angiotensin System Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 1257-1266. PMID 12171785 DOI: 10.1161/01.Atv.0000021412.56621.A2 |
0.419 |
|
| 2002 |
Pazdrak K, Olszewska-Pazdrak B, Liu T, Takizawa R, Brasier AR, Garofalo RP, Casola A. MAPK activation is involved in posttranscriptional regulation of RSV-induced RANTES gene expression. American Journal of Physiology-Lung Cellular and Molecular Physiology. 283. PMID 12114198 DOI: 10.1152/Ajplung.00331.2001 |
0.435 |
|
| 2002 |
Casola A, Garofalo RP, Crawford SE, Estes MK, Mercurio F, Crowe SE, Brasier AR. Interleukin-8 gene regulation in intestinal epithelial cells infected with rotavirus: role of viral-induced IkappaB kinase activation. Virology. 298: 8-19. PMID 12093168 DOI: 10.1006/Viro.2002.1475 |
0.462 |
|
| 2002 |
Tian B, Zhang Y, Luxon BA, Garofalo RP, Casola A, Sinha M, Brasier AR. Identification of NF-κB-Dependent Gene Networks in Respiratory Syncytial Virus-Infected Cells Journal of Virology. 76: 6800-6814. PMID 12050393 DOI: 10.1128/Jvi.76.13.6800-6814.2002 |
0.408 |
|
| 2002 |
Ray S, Sherman CT, Lu M, Brasier AR. Angiotensinogen gene expression is dependent on signal transducer and activator of transcription 3-mediated p300/cAMP response element binding protein-binding protein coactivator recruitment and histone acetyltransferase activity. Molecular Endocrinology (Baltimore, Md.). 16: 824-36. PMID 11923478 DOI: 10.1210/Mend.16.4.0811 |
0.418 |
|
| 2001 |
Brasier AR, Sherman CT, Jamaluddin M. Analysis of Transcriptional Control Mechanisms II Techniques for Characterization of trans-Acting Factors. Methods in Molecular Medicine. 51: 127-150. PMID 21331713 DOI: 10.1385/1-59259-087-X:127 |
0.364 |
|
| 2001 |
Sherman CT, Brasier AR. A nalysis of Transcriptional Control Mechanisms I Methods in Molecular Medicine. 51: 107-125. PMID 21331712 DOI: 10.1385/1-59259-087-X:107 |
0.318 |
|
| 2001 |
Zhang Y, Luxon BA, Casola A, Garofalo RP, Jamaluddin M, Brasier AR. Expression of respiratory syncytial virus-induced chemokine gene networks in lower airway epithelial cells revealed by cDNA microarrays. Journal of Virology. 75: 9044-58. PMID 11533168 DOI: 10.1128/Jvi.75.19.9044-9058.2001 |
0.385 |
|
| 2001 |
Lu Y, Jamieson L, Brasier AR, Fields AP. NF-kappaB/RelA transactivation is required for atypical protein kinase C iota-mediated cell survival. Oncogene. 20: 4777-92. PMID 11521190 DOI: 10.1038/Sj.Onc.1204607 |
0.386 |
|
| 2001 |
Casola A, Garofalo RP, Haeberle H, Elliott TF, Lin R, Jamaluddin M, Brasier AR. Multiple cis regulatory elements control RANTES promoter activity in alveolar epithelial cells infected with respiratory syncytial virus. Journal of Virology. 75: 6428-39. PMID 11413310 DOI: 10.1128/Jvi.75.14.6428-6439.2001 |
0.397 |
|
| 2001 |
Brasier AR, Lu M, Hai T, Lu Y, Boldogh I. NF-κB inducible BCL-3 expression is an autoregulatory loop controlling nuclear p50/NF-κB1 residence Journal of Biological Chemistry. 276: 32080-32093. PMID 11387332 DOI: 10.1074/Jbc.M102949200 |
0.39 |
|
| 2001 |
Casola A, Burger N, Liu T, Jamaluddin M, Brasier AR, Garofalo RP. Oxidant tone regulates RANTES gene expression in airway epithelial cells infected with respiratory syncytial virus. Role in viral-induced interferon regulatory factor activation. Journal of Biological Chemistry. 276: 19715-19722. PMID 11259439 DOI: 10.1074/Jbc.M101526200 |
0.437 |
|
| 2001 |
Sherman CT, Brasier AR. Role of signal transducers and activators of transcription 1 and -3 in inducible regulation of the human angiotensinogen gene by interleukin-6. Molecular Endocrinology. 15: 441-457. PMID 11222745 DOI: 10.1210/Mend.15.3.0609 |
0.441 |
|
| 2000 |
Casola A, Garofalo RP, Jamaluddin M, Vlahopoulos S, Brasier AR. Requirement of a novel upstream response element in respiratory syncytial virus-induced IL-8 gene expression. Journal of Immunology. 164: 5944-5951. PMID 10820277 DOI: 10.4049/Jimmunol.164.11.5944 |
0.444 |
|
| 2000 |
Jamaluddin M, Meng T, Sun J, Boldogh I, Han Y, Brasier AR. Angiotensin II induces nuclear factor (NF)-kappaB1 isoforms to bind the angiotensinogen gene acute-phase response element: a stimulus-specific pathway for NF-kappaB activation. Molecular Endocrinology (Baltimore, Md.). 14: 99-113. PMID 10628750 DOI: 10.1210/Mend.14.1.0400 |
0.426 |
|
| 2000 |
Brasier AR, Jamaluddin M, Han Y, Patterson C, Runge MS. Angiotensin II induces gene transcription through cell-type-dependent effects on the nuclear factor-κB (NF-κB) transcription factor Molecular and Cellular Biochemistry. 212: 155-169. DOI: 10.1023/A:1007133710837 |
0.453 |
|
| 2000 |
Olsewska-Pazdrak B, Pazdrak K, Brasier AR, Garofalo RP. 518 Activation of the transcription factor nuclear factor (NF)-κB in human eosinophils: Role in respiratory syncytial virus-mediated RANTES production The Journal of Allergy and Clinical Immunology. 105. DOI: 10.1016/S0091-6749(00)90946-1 |
0.365 |
|
| 1999 |
Han Y, Runge MS, Brasier AR. Angiotensin II induces interleukin-6 transcription in vascular smooth muscle cells through pleiotropic activation of nuclear factor-kappa B transcription factors. Circulation Research. 84: 695-703. PMID 10189357 DOI: 10.1161/01.Res.84.6.695 |
0.486 |
|
| 1999 |
Han Y, Meng T, Murray NR, Fields AP, Brasier AR. Interleukin-1-induced nuclear factor-kappaB-IkappaBalpha autoregulatory feedback loop in hepatocytes. A role for protein kinase calpha in post-transcriptional regulation of ikappabalpha resynthesis. The Journal of Biological Chemistry. 274: 939-47. PMID 9873035 DOI: 10.1074/Jbc.274.2.939 |
0.409 |
|
| 1999 |
Han Y, Weinman S, Boldogh I, Walker RK, Brasier AR. Tumor necrosis factor, α-inducible IκBα proteolysis mediated by cytosolic M-calpain: A mechanism parallel to tile ubiquitin-proteasome pathway for nuclear factor-κB activation Journal of Biological Chemistry. 274: 787-794. PMID 9873017 DOI: 10.1074/Jbc.274.2.787 |
0.401 |
|
| 1999 |
Vlahopoulos S, Boldogh I, Casola A, Brasier AR. Nuclear factor-kappaB-dependent Induction of interleukin-8 Gene Expression by Tumor Necrosis Factor Alpha: Evidence for an Antioxidant Sensitive Activating Pathway Distinct From Nuclear Translocation Blood. 94: 1878-1889. DOI: 10.1182/Blood.V94.6.1878.418K03_1878_1889 |
0.484 |
|
| 1998 |
Jamaluddin M, Casola A, Garofalo RP, Han Y, Elliott T, Ogra PL, Brasier AR. The Major Component of IκBα Proteolysis Occurs Independently of the Proteasome Pathway in Respiratory Syncytial Virus-Infected Pulmonary Epithelial Cells Journal of Virology. 72: 4849-4857. PMID 9573251 DOI: 10.1128/Jvi.72.6.4849-4857.1998 |
0.478 |
|
| 1998 |
Brasier AR, Jamaluddin M, Casola A, Duan W, Shen Q, Garofalo RP. A Promoter Recruitment Mechanism for Tumor Necrosis Factor-α-induced Interleukin-8 Transcription in Type II Pulmonary Epithelial Cells DEPENDENCE ON NUCLEAR ABUNDANCE OF Rel A, NF-κB1, AND c-Rel TRANSCRIPTION FACTORS Journal of Biological Chemistry. 273: 3551-3561. PMID 9452482 DOI: 10.1074/Jbc.273.6.3551 |
0.462 |
|
| 1998 |
Casola A, Garofalo RP, Ogra PL, Crawford SE, Estes MK, Brasier AR, Crowe SE. IL-8 gene regulation in rota virus-infected intestinal epithelial cells Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)83861-4 |
0.369 |
|
| 1997 |
Brasier AR, Han Y, Sherman CT. Transcriptional regulation of angiotensinogen gene expression. Vitamins and Hormones Series. 57: 217-247. PMID 10232051 DOI: 10.1016/S0083-6729(08)60645-7 |
0.417 |
|
| 1997 |
Han Y, Brasier AR. Mechanism for Biphasic Rel A· NF-κB1 Nuclear Translocation in Tumor Necrosis Factor α-stimulated Hepatocytes Journal of Biological Chemistry. 272: 9825-9832. PMID 9092517 DOI: 10.1074/Jbc.272.15.9825 |
0.407 |
|
| 1996 |
Li J, Brasier AR. Angiotensinogen gene activation by angiotensin II is mediated by the rel A (nuclear factor-kappaB p65) transcription factor: one mechanism for the renin angiotensin system positive feedback loop in hepatocytes. Molecular Endocrinology. 10: 252-264. PMID 8833654 DOI: 10.1210/Mend.10.3.8833654 |
0.42 |
|
| 1996 |
Jamaluddin M, Garofalo R, Ogra PL, Brasier AR. Inducible translational regulation of the NF-IL6 transcription factor by respiratory syncytial virus infection in pulmonary epithelial cells. Journal of Virology. 70: 1554-1563. PMID 8627674 DOI: 10.1128/Jvi.70.3.1554-1563.1996 |
0.456 |
|
| 1996 |
Brasier AR, Li J, Wimbish KA. Tumor Necrosis Factor Activates Angiotensinogen Gene Expression by the Rel A Transactivator Hypertension. 27: 1009-1017. PMID 8613256 DOI: 10.1161/01.Hyp.27.4.1009 |
0.416 |
|
| 1996 |
Brasier AR, Li J. Mechanisms for Inducible Control of Angiotensinogen Gene Transcription Hypertension. 27: 465-475. PMID 8613188 DOI: 10.1161/01.Hyp.27.3.465 |
0.434 |
|
| 1996 |
Garofalo R, Sabry M, Yu K, Casola A, Saito T, Jamaluddin M, Ogra PL, Brasier AR. IL-8 INDUCTION BY RESPIRATORY SYNCYTIAL VIRUS (RSV) INFECTION IS MEDIATED BY RelA (NF-kB) TRANSCRIPTION FACTOR. |[bull]| 49 Pediatric Research. 39: 11-11. DOI: 10.1203/00006450-199604001-00068 |
0.456 |
|
| 1995 |
Brasier AR, Kumar A. The Basic Amino Acid-Rich DNA-Binding Element of the NF-IL6 Transcription Factor Contains Two Functionally Distinct Subdomains. American Journal of Therapeutics. 2: 666-675. PMID 11854844 DOI: 10.1097/00045391-199509000-00015 |
0.394 |
|
| 1995 |
Holland OB, Carr B, Brasier AR. Aldosterone synthase gene regulation by angiotensin. Endocrine Research. 21: 455-462. PMID 7588410 DOI: 10.3109/07435809509030462 |
0.35 |
|
| 1994 |
Brasier AR, Li J, Copland A. Transcription factors modulating angiotensinogen gene expression in hepatocytes. Kidney International. 46: 1564-6. PMID 7700007 DOI: 10.1038/Ki.1994.447 |
0.457 |
|
| 1993 |
McGehee RE, Ron D, Brasier AR, Habener JF. Differentiation-specific element: a cis-acting developmental switch required for the sustained transcriptional expression of the angiotensinogen gene during hormonal-induced differentiation of 3T3-L1 fibroblasts to adipocytes. Molecular Endocrinology (Baltimore, Md.). 7: 551-60. PMID 7684818 DOI: 10.1210/Mend.7.4.7684818 |
0.343 |
|
| 1993 |
Brasier AR, Ron D. Luciferase reporter gene assay in mammalian cells. Methods in Enzymology. 216: 386-97. PMID 1336098 DOI: 10.1016/0076-6879(92)16036-J |
0.328 |
|
| 1992 |
Ron D, Brasier AR, McGehee RE, Habener JF. Tumor necrosis factor-induced reversal of adipocytic phenotype of 3T3-L1 cells is preceded by a loss of nuclear CCAAT/enhancer binding protein (C/EBP). The Journal of Clinical Investigation. 89: 223-33. PMID 1729273 DOI: 10.1172/Jci115566 |
0.395 |
|
| 1991 |
Ron D, Brasier AR, Habener JF. Angiotensinogen gene-inducible enhancer-binding protein 1, a member of a new family of large nuclear proteins that recognize nuclear factor kappa B-binding sites through a zinc finger motif. Molecular and Cellular Biology. 11: 2887-95. PMID 2017183 DOI: 10.1128/Mcb.11.5.2887 |
0.353 |
|
| 1991 |
Brasier AR, Ron D. Use of Firefly Luciferase Reporter Gene to Study Angiotensinogen Acute Phase Response Element Methods in Neurosciences. 5: 108-123. DOI: 10.1016/B978-0-12-185259-7.50012-0 |
0.319 |
|
| 1990 |
Ron D, Brasier AR, Wright KA, Habener JF. The permissive role of glucocorticoids on interleukin-1 stimulation of angiotensinogen gene transcription is mediated by an interaction between inducible enhancers. Molecular and Cellular Biology. 10: 4389-95. PMID 2370871 DOI: 10.1128/mcb.10.8.4389-4395.1990 |
0.372 |
|
| 1990 |
Ron D, Brasier AR, Wright KA, Tate JE, Habener JF. An inducible 50-kilodalton NF kappa B-like protein and a constitutive protein both bind the acute-phase response element of the angiotensinogen gene. Molecular and Cellular Biology. 10: 1023-32. PMID 2106065 DOI: 10.1128/Mcb.10.3.1023 |
0.387 |
|
| 1990 |
Brasier AR, Ron D, Tate JE, Habener JF. Synergistic enhansons located within an acute phase responsive enhancer modulate glucocorticoid induction of angiotensinogen gene transcription. Molecular Endocrinology (Baltimore, Md.). 4: 1921-33. PMID 1707127 DOI: 10.1210/Mend-4-12-1921 |
0.403 |
|
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