| Year |
Citation |
Score |
| 2022 |
Basisty N, Shulman N, Wehrfritz C, Marsh AN, Shah S, Rose J, Ebert S, Miller M, Dai DF, Rabinovitch PS, Adams CM, MacCoss MJ, MacLean B, Schilling B. TurnoveR: A Skyline External Tool for Analysis of Protein Turnover in Metabolic Labeling Studies. Journal of Proteome Research. PMID 36165806 DOI: 10.1021/acs.jproteome.2c00173 |
0.589 |
|
| 2021 |
Daneshgar N, Rabinovitch PS, Dai DF. TOR Signaling Pathway in Cardiac Aging and Heart Failure. Biomolecules. 11. PMID 33513917 DOI: 10.3390/biom11020168 |
0.633 |
|
| 2020 |
Whitson JA, Bitto A, Zhang H, Sweetwyne MT, Coig R, Bhayana S, Shankland EG, Wang L, Bammler TK, Mills KF, Imai SI, Conley KE, Marcinek DJ, Rabinovitch PS. SS-31 and NMN: Two paths to improve metabolism and function in aged hearts. Aging Cell. e13213. PMID 32779818 DOI: 10.1111/Acel.13213 |
0.349 |
|
| 2020 |
Chiao YA, Zhang H, Sweetwyne M, Whitson J, Ting YS, Basisty N, Pino LK, Quarles E, Nguyen NH, Campbell MD, Zhang T, Gaffrey MJ, Merrihew G, Wang L, Yue Y, ... ... Rabinovitch P, et al. Late-life restoration of mitochondrial function reverses cardiac dysfunction in old mice. Elife. 9. PMID 32648542 DOI: 10.7554/Elife.55513 |
0.403 |
|
| 2020 |
Chavez JD, Tang X, Campbell MD, Reyes G, Kramer PA, Stuppard R, Keller A, Zhang H, Rabinovitch PS, Marcinek DJ, Bruce JE. Mitochondrial protein interaction landscape of SS-31. Proceedings of the National Academy of Sciences of the United States of America. PMID 32554501 DOI: 10.1073/Pnas.2002250117 |
0.347 |
|
| 2020 |
Chiao YA, Zhang H, Sweetwyne M, Whitson J, Ting YS, Basisty N, Pino LK, Quarles E, Nguyen N, Campbell MD, Zhang T, Gaffrey MJ, Merrihew G, Wang L, Yue Y, ... ... Rabinovitch P, et al. Author response: Late-life restoration of mitochondrial function reverses cardiac dysfunction in old mice Elife. DOI: 10.7554/Elife.55513.Sa2 |
0.339 |
|
| 2019 |
Quarles E, Basisty N, Chiao YA, Merrihew G, Gu H, Sweetwyne MT, Fredrickson J, Nguyen NH, Razumova M, Kooiker K, Moussavi-Harami F, Regnier M, Quarles C, MacCoss M, Rabinovitch PS. Rapamycin persistently improves cardiac function in aged, male and female mice, even following cessation of treatment. Aging Cell. e13086. PMID 31823466 DOI: 10.1111/Acel.13086 |
0.343 |
|
| 2019 |
Dai DF, Liu Y, Basisty N, Karunadharma P, Dastidar SG, Chiao YA, Chen T, Beyer RP, Chin MT, Maccoss M, La Spada AR, Rabinovitch PS. Differential effects of various genetic mouse models of the mechanistic target of rapamycin complex I inhibition on heart failure. Geroscience. PMID 31650481 DOI: 10.1007/s11357-019-00119-6 |
0.632 |
|
| 2019 |
Zhang H, Szeto H, Alder N, Rabinovitch PS. Abstract 287: Altered Mitochondrial Flash Activity and mPTP Opening in the Aged Heart Are Reversed by Elamipretide Treatment Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.287 |
0.348 |
|
| 2019 |
Valencia AP, Whitson J, Stuppard R, Valencia G, Rabinovitch P, Marcinek D. AGED MICE ARE SUSCEPTIBLE TO CARDIAC HYPERTROPHY AFTER 1 WEEK OF CONSUMING A HIGH SUGAR DIET Innovation in Aging. 3: S108-S108. DOI: 10.1093/Geroni/Igz038.402 |
0.357 |
|
| 2018 |
Campbell MD, Duan J, Samuelson AT, Gaffrey MJ, Wang L, Bammler TK, Moore RJ, White CC, Kavanagh TJ, Voss JG, Szeto HH, Rabinovitch PS, Qian WJ, Marcinek DJ. Improving mitochondrial function with SS-31 reverses age-related redox stress and improves exercise tolerance in aged mice. Free Radical Biology & Medicine. PMID 30597195 DOI: 10.1016/J.Freeradbiomed.2018.12.031 |
0.382 |
|
| 2018 |
Tarantini S, Valcarcel-Ares NM, Yabluchanskiy A, Fulop GA, Hertelendy P, Gautam T, Farkas E, Perz A, Rabinovitch PS, Sonntag WE, Csiszar A, Ungvari Z. Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice. Aging Cell. PMID 29405550 DOI: 10.1111/Acel.12731 |
0.373 |
|
| 2018 |
Rabinovitch P, Marcinek DJ. THE ROLE OF MITOCHONDRIAL ENERGETICS IN CARDIAC AND SKELETAL MUSCLE AGING Innovation in Aging. 2: 348-348. DOI: 10.1093/Geroni/Igy023.1278 |
0.333 |
|
| 2017 |
Basisty NB, Liu Y, Reynolds J, Karunadharma PP, Dai DF, Fredrickson J, Beyer RP, MacCoss MJ, Rabinovitch PS. Stable Isotope Labeling Reveals Novel Insights Into Ubiquitin-Mediated Protein Aggregation With Age, Calorie Restriction, and Rapamycin Treatment. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 28958078 DOI: 10.1093/Gerona/Glx047 |
0.647 |
|
| 2017 |
Ladiges W, Snyder JM, Wilkinson E, Imai DM, Snider T, Ge X, Ciol M, Pettan-Brewer C, Pillai SP, Morton J, Quarles E, Rabinovitch P, Niedernhofer L, Liggitt D. A New Preclinical Paradigm for Testing Anti-Aging Therapeutics. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 28329081 DOI: 10.1093/Gerona/Glx019 |
0.326 |
|
| 2017 |
Dai DF, Chiao YA, Martin GM, Marcinek DJ, Basisty N, Quarles EK, Rabinovitch PS. Mitochondrial-Targeted Catalase: Extended Longevity and the Roles in Various Disease Models. Progress in Molecular Biology and Translational Science. 146: 203-241. PMID 28253986 DOI: 10.1016/Bs.Pmbts.2016.12.015 |
0.399 |
|
| 2017 |
Sweetwyne MT, Pippin JW, Eng DG, Hudkins KL, Chiao YA, Campbell MD, Marcinek DJ, Alpers CE, Szeto HH, Rabinovitch PS, Shankland SJ. The mitochondrial-targeted peptide, SS-31, improves glomerular architecture in mice of advanced age. Kidney International. PMID 28063595 DOI: 10.1016/J.Kint.2016.10.036 |
0.395 |
|
| 2016 |
Basisty N, Dai DF, Gagnidze A, Gitari L, Fredrickson J, Maina Y, Beyer RP, Emond MJ, Hsieh EJ, MacCoss MJ, Martin GM, Rabinovitch PS. Mitochondrial-targeted catalase is good for the old mouse proteome, but not for the young: 'reverse' antagonistic pleiotropy? Aging Cell. PMID 27061426 DOI: 10.1111/Acel.12472 |
0.678 |
|
| 2016 |
Pires KM, Buffolo M, Valenca S, Rabinovitch P, Boudina S. Reduced Mitochondrial Oxidative Stress Impairs Brown Adipose Tissue-Mediated Thermogenesis in Mice Free Radical Biology and Medicine. 100: S177. DOI: 10.1016/J.Freeradbiomed.2016.10.468 |
0.303 |
|
| 2015 |
Kaeberlein M, Rabinovitch PS, Martin GM. Healthy aging: The ultimate preventative medicine Science. 350: 1191-1193. PMID 26785476 DOI: 10.1126/Science.Aad3267 |
0.31 |
|
| 2015 |
Zaha VG, Qi D, Su KN, Palmeri M, Lee HY, Hu X, Wu X, Shulman GI, Rabinovitch PS, Russell R, Young LH. AMPK is critical for mitochondrial function during reperfusion after myocardial ischemia. Journal of Molecular and Cellular Cardiology. PMID 26746142 DOI: 10.1016/J.Yjmcc.2015.12.032 |
0.347 |
|
| 2015 |
Kruse SE, Karunadharma PP, Basisty N, Johnson R, Beyer RP, MacCoss MJ, Rabinovitch PS, Marcinek DJ. Age modifies respiratory complex I and protein homeostasis in a muscle type-specific manner. Aging Cell. PMID 26498839 DOI: 10.1111/Acel.12412 |
0.383 |
|
| 2015 |
Chiao YA, Rabinovitch PS. The Aging Heart. Cold Spring Harbor Perspectives in Medicine. 5: a025148. PMID 26328932 DOI: 10.1101/Cshperspect.A025148 |
0.338 |
|
| 2015 |
Johnson SC, Yanos ME, Bitto A, Castanza A, Gagnidze A, Gonzalez B, Gupta K, Hui J, Jarvie C, Johnson BM, Letexier N, McCanta L, Sangesland M, Tamis O, Uhde L, ... ... Rabinovitch PS, et al. Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in mice. Frontiers in Genetics. 6: 247. PMID 26257774 DOI: 10.3389/Fgene.2015.00247 |
0.663 |
|
| 2015 |
Griffith AV, Venables T, Shi J, Farr A, van Remmen H, Szweda L, Fallahi M, Rabinovitch P, Petrie HT. Metabolic Damage and Premature Thymus Aging Caused by Stromal Catalase Deficiency. Cell Reports. 12: 1071-9. PMID 26257169 DOI: 10.1016/J.Celrep.2015.07.008 |
0.325 |
|
| 2015 |
Srivastava A, Golden KL, Sanchez CA, Liu K, Fong PY, Li X, Cowan DS, Rabinovitch PS, Reid BJ, Blount PL, Odze RD. High Goblet Cell Count Is Inversely Associated with Ploidy Abnormalities and Risk of Adenocarcinoma in Barrett's Esophagus. Plos One. 7: e0133403. PMID 26230607 DOI: 10.1371/Journal.Pone.0133403 |
0.309 |
|
| 2015 |
Tocchi A, Quarles EK, Basisty N, Gitari L, Rabinovitch PS. Mitochondrial dysfunction in cardiac aging. Biochimica Et Biophysica Acta. 1847: 1424-33. PMID 26191650 DOI: 10.1016/J.Bbabio.2015.07.009 |
0.392 |
|
| 2015 |
Ping P, Gustafsson ÅB, Bers DM, Blatter LA, Cai H, Jahangir A, Kelly D, Muoio D, O'Rourke B, Rabinovitch P, Trayanova N, Van Eyk J, Weiss JN, Wong R, Schwartz Longacre L. Harnessing the Power of Integrated Mitochondrial Biology and Physiology: A Special Report on the NHLBI Mitochondria in Heart Diseases Initiative. Circulation Research. 117: 234-238. PMID 26185209 DOI: 10.1161/Circresaha.117.306693 |
0.319 |
|
| 2015 |
Roeder SS, Stefanska A, Eng DG, Kaverina N, Sunseri MW, McNicholas BA, Rabinovitch P, Engel FB, Daniel C, Amann K, Lichtnekert J, Pippin JW, Shankland SJ. Changes in glomerular parietal epithelial cells in mouse kidneys with advanced age. American Journal of Physiology. Renal Physiology. 309: F164-78. PMID 26017974 DOI: 10.1152/Ajprenal.00144.2015 |
0.356 |
|
| 2015 |
Karunadharma PP, Basisty N, Chiao YA, Dai DF, Drake R, Levy N, Koh WJ, Emond MJ, Kruse S, Marcinek D, Maccoss MJ, Rabinovitch PS. Respiratory chain protein turnover rates in mice are highly heterogeneous but strikingly conserved across tissues, ages, and treatments. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 25977255 DOI: 10.1096/Fj.15-272666 |
0.654 |
|
| 2015 |
Karunadharma PP, Basisty N, Dai DF, Chiao YA, Quarles EK, Hsieh EJ, Crispin D, Bielas JH, Ericson NG, Beyer RP, MacKay VL, MacCoss MJ, Rabinovitch PS. Subacute calorie restriction and rapamycin discordantly alter mouse liver proteome homeostasis and reverse aging effects. Aging Cell. 14: 547-57. PMID 25807975 DOI: 10.1111/Acel.12317 |
0.65 |
|
| 2015 |
Quarles EK, Dai DF, Tocchi A, Basisty N, Gitari L, Rabinovitch PS. Quality control systems in cardiac aging. Ageing Research Reviews. 23: 101-15. PMID 25702865 DOI: 10.1016/J.Arr.2015.02.003 |
0.656 |
|
| 2015 |
Johnson SC, Sangesland M, Kaeberlein M, Rabinovitch PS. Modulating mTOR in aging and health. Interdisciplinary Topics in Gerontology. 40: 107-27. PMID 25341517 DOI: 10.1159/000364974 |
0.641 |
|
| 2014 |
Song M, Chen Y, Gong G, Murphy E, Rabinovitch PS, Dorn GW. Super-suppression of mitochondrial reactive oxygen species signaling impairs compensatory autophagy in primary mitophagic cardiomyopathy. Circulation Research. 115: 348-53. PMID 24874428 DOI: 10.1161/Circresaha.115.304384 |
0.336 |
|
| 2014 |
Dai DF, Chiao YA, Marcinek DJ, Szeto HH, Rabinovitch PS. Mitochondrial oxidative stress in aging and healthspan. Longevity & Healthspan. 3: 6. PMID 24860647 DOI: 10.1186/2046-2395-3-6 |
0.652 |
|
| 2014 |
Puente BN, Kimura W, Muralidhar SA, Moon J, Amatruda JF, Phelps KL, Grinsfelder D, Rothermel BA, Chen R, Garcia JA, Santos CX, Thet S, Mori E, Kinter MT, Rindler PM, ... ... Rabinovitch PS, et al. The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response. Cell. 157: 565-79. PMID 24766806 DOI: 10.1016/J.Cell.2014.03.032 |
0.355 |
|
| 2014 |
Dai DF, Karunadharma PP, Chiao YA, Basisty N, Crispin D, Hsieh EJ, Chen T, Gu H, Djukovic D, Raftery D, Beyer RP, MacCoss MJ, Rabinovitch PS. Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart. Aging Cell. 13: 529-39. PMID 24612461 DOI: 10.1111/Acel.12203 |
0.672 |
|
| 2014 |
Wang Y, Wang GZ, Rabinovitch PS, Tabas I. Macrophage mitochondrial oxidative stress promotes atherosclerosis and nuclear factor-κB-mediated inflammation in macrophages. Circulation Research. 114: 421-33. PMID 24297735 DOI: 10.1161/Circresaha.114.302153 |
0.33 |
|
| 2014 |
Chiao YA, Basisty N, Sonia Ting Y, Szeto HH, MacCoss MJ, Rabinovitch PS. Short Term Treatment with Mitochondrial Protective Peptide Reverses Cardiac Aging in Mice Free Radical Biology and Medicine. 76: S31. DOI: 10.1016/J.Freeradbiomed.2014.10.440 |
0.344 |
|
| 2014 |
Campbell MD, Chiao YA, Gaffrey MJ, Djukovic D, Gu H, Szeto HS, Raftery D, Rabinovitch P, Qian W, Marcinek DJ. Targeting Mitochondrial Oxidative Stress to Improve Aged Skeletal Muscle Function Free Radical Biology and Medicine. 76: S29. DOI: 10.1016/J.Freeradbiomed.2014.10.436 |
0.326 |
|
| 2014 |
Puente BN, Kimura W, Muralidhar SA, Moon J, Amatruda JF, Phelps KL, Grinsfelder D, Rothermel BA, Chen R, Garcia JA, Santos CX, Thet S, Mori E, Kinter MT, Rindler PM, ... ... Rabinovitch PS, et al. Erratum: The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response (Cell (2014) 157 (741-743)) Cell. 157. DOI: 10.1016/J.Cell.2014.05.008 |
0.303 |
|
| 2013 |
Johnson SC, Yanos ME, Kayser EB, Quintana A, Sangesland M, Castanza A, Uhde L, Hui J, Wall VZ, Gagnidze A, Oh K, Wasko BM, Ramos FJ, Palmiter RD, Rabinovitch PS, et al. mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome. Science (New York, N.Y.). 342: 1524-8. PMID 24231806 DOI: 10.1126/Science.1244360 |
0.683 |
|
| 2013 |
Johnson SC, Martin GM, Rabinovitch PS, Kaeberlein M. Preserving youth: does rapamycin deliver? Science Translational Medicine. 5: 211fs40. PMID 24225941 DOI: 10.1126/Scitranslmed.3007316 |
0.639 |
|
| 2013 |
Dai DF, Hsieh EJ, Chen T, Menendez LG, Basisty NB, Tsai L, Beyer RP, Crispin DA, Shulman NJ, Szeto HH, Tian R, MacCoss MJ, Rabinovitch PS. Global proteomics and pathway analysis of pressure-overload-induced heart failure and its attenuation by mitochondrial-targeted peptides. Circulation. Heart Failure. 6: 1067-76. PMID 23935006 DOI: 10.1161/Circheartfailure.113.000406 |
0.646 |
|
| 2013 |
Schleit J, Johnson SC, Bennett CF, Simko M, Trongtham N, Castanza A, Hsieh EJ, Moller RM, Wasko BM, Delaney JR, Sutphin GL, Carr D, Murakami CJ, Tocchi A, Xian B, ... ... Rabinovitch PS, et al. Molecular mechanisms underlying genotype-dependent responses to dietary restriction. Aging Cell. 12: 1050-61. PMID 23837470 DOI: 10.1111/Acel.12130 |
0.681 |
|
| 2013 |
Siegel MP, Kruse SE, Percival JM, Goh J, White CC, Hopkins HC, Kavanagh TJ, Szeto HH, Rabinovitch PS, Marcinek DJ. Mitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice. Aging Cell. 12: 763-71. PMID 23692570 DOI: 10.1111/Acel.12102 |
0.365 |
|
| 2013 |
Johnson SC, Rabinovitch PS, Kaeberlein M. mTOR is a key modulator of ageing and age-related disease. Nature. 493: 338-45. PMID 23325216 DOI: 10.1038/Nature11861 |
0.669 |
|
| 2013 |
Edward Kruse S, Karunadharma P, MacCoss M, Rabinovitch P. Divergent Effects of Age on Mitochondrial Function in Fast Twitch and Slow Twitch Skeletal Muscle Free Radical Biology and Medicine. 65: S116. DOI: 10.1016/J.Freeradbiomed.2013.10.681 |
0.311 |
|
| 2012 |
Frock RL, Chen SC, Da DF, Frett E, Lau C, Brown C, Pak DN, Wang Y, Muchir A, Worman HJ, Santana LF, Ladiges WC, Rabinovitch PS, Kennedy BK. Cardiomyocyte-specific expression of lamin a improves cardiac function in Lmna-/- mice. Plos One. 7: e42918. PMID 22905185 DOI: 10.1371/Journal.Pone.0042918 |
0.321 |
|
| 2012 |
Hsieh EJ, Shulman NJ, Dai DF, Vincow ES, Karunadharma PP, Pallanck L, Rabinovitch PS, MacCoss MJ. Topograph, a software platform for precursor enrichment corrected global protein turnover measurements. Molecular & Cellular Proteomics : McP. 11: 1468-74. PMID 22865922 DOI: 10.1074/Mcp.O112.017699 |
0.613 |
|
| 2012 |
Ramos FJ, Chen SC, Garelick MG, Dai DF, Liao CY, Schreiber KH, MacKay VL, An EH, Strong R, Ladiges WC, Rabinovitch PS, Kaeberlein M, Kennedy BK. Rapamycin reverses elevated mTORC1 signaling in lamin A/C-deficient mice, rescues cardiac and skeletal muscle function, and extends survival. Science Translational Medicine. 4: 144ra103. PMID 22837538 DOI: 10.1126/Scitranslmed.3003802 |
0.641 |
|
| 2012 |
Johnson S, Rabinovitch P. Ex Vivo Imaging of Excised Tissue Using Vital Dyes and Confocal Microscopy Current Protocols in Immunology. 61. PMID 22752953 DOI: 10.1002/0471142956.Cy0939S61 |
0.63 |
|
| 2012 |
Dai DF, Rabinovitch PS, Ungvari Z. Mitochondria and cardiovascular aging. Circulation Research. 110: 1109-24. PMID 22499901 DOI: 10.1161/Circresaha.111.246140 |
0.679 |
|
| 2012 |
Mao P, Manczak M, Calkins MJ, Truong Q, Reddy TP, Reddy AP, Shirendeb U, Lo HH, Rabinovitch PS, Reddy PH. Mitochondria-targeted catalase reduces abnormal APP processing, amyloid β production and BACE1 in a mouse model of Alzheimer's disease: implications for neuroprotection and lifespan extension. Human Molecular Genetics. 21: 2973-90. PMID 22492996 DOI: 10.1093/Hmg/Dds128 |
0.311 |
|
| 2012 |
Dai DF, Chen T, Johnson SC, Szeto H, Rabinovitch PS. Cardiac aging: from molecular mechanisms to significance in human health and disease. Antioxidants & Redox Signaling. 16: 1492-526. PMID 22229339 DOI: 10.1089/Ars.2011.4179 |
0.777 |
|
| 2012 |
Dai DF, Hsieh EJ, Liu Y, Chen T, Beyer RP, Chin MT, MacCoss MJ, Rabinovitch PS. Mitochondrial proteome remodelling in pressure overload-induced heart failure: The role of mitochondrial oxidative stress Cardiovascular Research. 93: 79-88. PMID 22012956 DOI: 10.1093/Cvr/Cvr274 |
0.649 |
|
| 2012 |
Frock RL, Chen SC, Dai D, Frett E, Lau C, Brown C, Pak DN, Wang Y, Muchir A, Worman HJ, Santana LF, Ladiges WC, Rabinovitch PS, Kennedy BK. Correction: Cardiomyocyte-Specific Expression of Lamin A Improves Cardiac Function in Lmna−/−Mice Plos One. 7. DOI: 10.1371/Annotation/92Be6B32-D8E7-44C2-80A9-21097Ad27965 |
0.611 |
|
| 2012 |
Risques RA, Ussakli C, Ebaee A, Brentnall T, Rabinovitch P. Abstract 1129: Mitochondrial dysfunction precedes tumor progression in ulcerative colitis, but it is restored in advanced dysplasia and cancer Cancer Research. 72: 1129-1129. DOI: 10.1158/1538-7445.Am2012-1129 |
0.353 |
|
| 2011 |
Dai DF, Chen T, Szeto H, Nieves-Cintrón M, Kutyavin V, Santana LF, Rabinovitch PS. Mitochondrial targeted antioxidant Peptide ameliorates hypertensive cardiomyopathy. Journal of the American College of Cardiology. 58: 73-82. PMID 21620606 DOI: 10.1016/J.Jacc.2010.12.044 |
0.638 |
|
| 2011 |
Dai DF, Rabinovitch P. Mitochondrial oxidative stress mediates induction of autophagy and hypertrophy in angiotensin-II treated mouse hearts. Autophagy. 7: 917-8. PMID 21505274 DOI: 10.4161/Auto.7.8.15813 |
0.672 |
|
| 2011 |
Dai DF, Johnson SC, Villarin JJ, Chin MT, Nieves-Cintrón M, Chen T, Marcinek DJ, Dorn GW, Kang YJ, Prolla TA, Santana LF, Rabinovitch PS. Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure. Circulation Research. 108: 837-46. PMID 21311045 DOI: 10.1161/Circresaha.110.232306 |
0.767 |
|
| 2010 |
Lee HY, Choi CS, Birkenfeld AL, Alves TC, Jornayvaz FR, Jurczak MJ, Zhang D, Woo DK, Shadel GS, Ladiges W, Rabinovitch PS, Santos JH, Petersen KF, Samuel VT, Shulman GI. Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance. Cell Metabolism. 12: 668-74. PMID 21109199 DOI: 10.1016/J.Cmet.2010.11.004 |
0.362 |
|
| 2010 |
Wanagat J, Dai DF, Rabinovitch P. Mitochondrial oxidative stress and mammalian healthspan. Mechanisms of Ageing and Development. 131: 527-35. PMID 20566356 DOI: 10.1016/J.Mad.2010.06.002 |
0.664 |
|
| 2010 |
Dai DF, Chen T, Wanagat J, Laflamme M, Marcinek DJ, Emond MJ, Ngo CP, Prolla TA, Rabinovitch PS. Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria. Aging Cell. 9: 536-44. PMID 20456298 DOI: 10.1111/J.1474-9726.2010.00581.X |
0.687 |
|
| 2010 |
Ladiges W, Wanagat J, Preston B, Loeb L, Rabinovitch P. A Mitochondrial view of aging, reactive oxygen species and metastatic cancer Aging Cell. 9: 462-465. PMID 20456297 DOI: 10.1111/J.1474-9726.2010.00579.X |
0.344 |
|
| 2010 |
Dhillon KK, Sidorova JM, Albertson TM, Anderson JB, Ladiges WC, Rabinovitch PS, Preston BD, Monnat RJ. Divergent cellular phenotypes of human and mouse cells lacking the Werner syndrome RecQ helicase. Dna Repair. 9: 11-22. PMID 19896421 DOI: 10.1016/J.Dnarep.2009.09.013 |
0.325 |
|
| 2010 |
Enns LC, Morton JF, Treuting PR, Emond MJ, Wolf NS, Dai D, McKnight GS, Rabinovitch PS, Ladiges WC. Correction: Disruption of Protein Kinase A in Mice Enhances Healthy Aging Plos One. 5. DOI: 10.1371/Annotation/D51A16B6-Dc82-4Cdb-8118-D7C982233D7C |
0.624 |
|
| 2010 |
Enns LC, Morton JF, Treuting PR, Emond MJ, Wolf NS, Dai D, McKnight GS, Rabinovitch PS, Ladiges WC. Correction: Disruption of Protein Kinase A in Mice Enhances Healthy Aging Plos One. 5. DOI: 10.1371/annotation/d51a16b6-dc82-4cdb-8118-d7c982233d7c |
0.611 |
|
| 2010 |
Pan S, Brentnall TA, Crispin DA, Bronner MP, Lai LA, May D, McIntosh M, Rabinovitch PS, Chen R. Abstract 4562: Alteration of mitochondrial proteome in neoplastic progression of ulcerative colitis Cancer Research. 70: 4562-4562. DOI: 10.1158/1538-7445.Am10-4562 |
0.35 |
|
| 2010 |
Marcinek DJ, Wanagat J, Rabinovitch PS, Voss J. 75 Protective effect of mitochondrial catalase on AZT mitochondrial toxicity Mitochondrion. 10: 221. DOI: 10.1016/J.Mito.2009.12.070 |
0.313 |
|
| 2009 |
Dai DF, Rabinovitch PS. Cardiac aging in mice and humans: the role of mitochondrial oxidative stress. Trends in Cardiovascular Medicine. 19: 213-20. PMID 20382344 DOI: 10.1016/J.Tcm.2009.12.004 |
0.688 |
|
| 2009 |
Someya S, Xu J, Kondo K, Ding D, Salvi RJ, Yamasoba T, Rabinovitch PS, Weindruch R, Leeuwenburgh C, Tanokura M, Prolla TA. Age-related hearing loss in C57BL/6J mice is mediated by Bak-dependent mitochondrial apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 106: 19432-7. PMID 19901338 DOI: 10.1073/Pnas.0908786106 |
0.384 |
|
| 2009 |
Enns LC, Morton JF, Mangalindan RS, McKnight GS, Schwartz MW, Kaeberlein MR, Kennedy BK, Rabinovitch PS, Ladiges WC. Attenuation of age-related metabolic dysfunction in mice with a targeted disruption of the Cbeta subunit of protein kinase A. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 1221-31. PMID 19776218 DOI: 10.1093/Gerona/Glp133 |
0.318 |
|
| 2009 |
Enns LC, Morton JF, Treuting PR, Emond MJ, Wolf NS, Dai DF, McKnight GS, Rabinovitch PS, Ladiges WC. Disruption of protein kinase A in mice enhances healthy aging. Plos One. 4: e5963. PMID 19536287 DOI: 10.1371/Journal.Pone.0005963 |
0.644 |
|
| 2009 |
Dai DF, Santana LF, Vermulst M, Tomazela DM, Emond MJ, MacCoss MJ, Gollahon K, Martin GM, Loeb LA, Ladiges WC, Rabinovitch PS. Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging. Circulation. 119: 2789-97. PMID 19451351 DOI: 10.1161/Circulationaha.108.822403 |
0.69 |
|
| 2009 |
Usui S, Komeima K, Lee SY, Jo YJ, Ueno S, Rogers BS, Wu Z, Shen J, Lu L, Oveson BC, Rabinovitch PS, Campochiaro PA. Increased expression of catalase and superoxide dismutase 2 reduces cone cell death in retinitis pigmentosa. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 778-86. PMID 19293779 DOI: 10.1038/Mt.2009.47 |
0.321 |
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| 2009 |
Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin CT, Price JW, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD. Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. The Journal of Clinical Investigation. 119: 573-81. PMID 19188683 DOI: 10.1172/Jci37048 |
0.323 |
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| 2009 |
Marcondes AM, Bair S, Rabinovitch PS, Gooley T, Deeg HJ, Risques R. No telomere shortening in marrow stroma from patients with MDS. Annals of Hematology. 88: 623-8. PMID 19050887 DOI: 10.1007/S00277-008-0649-7 |
0.351 |
|
| 2008 |
Treuting PM, Linford NJ, Knoblaugh SE, Emond MJ, Morton JF, Martin GM, Rabinovitch PS, Ladiges WC. Reduction of age-associated pathology in old mice by overexpression of catalase in mitochondria. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 63: 813-22. PMID 18772469 DOI: 10.1093/Gerona/63.8.813 |
0.376 |
|
| 2008 |
Poot M, Rosato M, Rabinovitch PS. Analysis of cell proliferation and cell survival by continuous BrdU labeling and multivariate flow cytometry. Current Protocols in Cytometry. Unit 7.14. PMID 18770726 DOI: 10.1002/0471142956.Cy0714S15 |
0.306 |
|
| 2008 |
Risques RA, Lai LA, Brentnall TA, Li L, Feng Z, Gallaher J, Mandelson MT, Potter JD, Bronner MP, Rabinovitch PS. Ulcerative colitis is a disease of accelerated colon aging: evidence from telomere attrition and DNA damage. Gastroenterology. 135: 410-8. PMID 18519043 DOI: 10.1053/J.Gastro.2008.04.008 |
0.302 |
|
| 2008 |
Vermulst M, Wanagat J, Kujoth GC, Bielas JH, Rabinovitch PS, Prolla TA, Loeb LA. DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice Nature Genetics. 40: 392-394. PMID 18311139 DOI: 10.1038/Ng.95 |
0.359 |
|
| 2007 |
Linford NJ, Beyer RP, Gollahon K, Krajcik RA, Malloy VL, Demas V, Burmer GC, Rabinovitch PS. Transcriptional response to aging and caloric restriction in heart and adipose tissue. Aging Cell. 6: 673-88. PMID 17874999 DOI: 10.1111/J.1474-9726.2007.00319.X |
0.325 |
|
| 2007 |
Vermulst M, Bielas JH, Kujoth GC, Ladiges WC, Rabinovitch PS, Prolla TA, Loeb LA. Mitochondrial point mutations do not limit the natural lifespan of mice Nature Genetics. 39: 540-543. PMID 17334366 DOI: 10.1038/Ng1988 |
0.343 |
|
| 2007 |
Dhillon KK, Sidorova J, Saintigny Y, Poot M, Gollahon K, Rabinovitch PS, Monnat RJ. Functional role of the Werner syndrome RecQ helicase in human fibroblasts. Aging Cell. 6: 53-61. PMID 17266675 DOI: 10.1111/J.1474-9726.2006.00260.X |
0.317 |
|
| 2006 |
O'Sullivan J, Risques RA, Mandelson MT, Chen L, Brentnall TA, Bronner MP, MacMillan MP, Feng Z, Siebert JR, Potter JD, Rabinovitch PS. Telomere length in the colon declines with age: A relation to colorectal cancer? Cancer Epidemiology Biomarkers and Prevention. 15: 573-577. PMID 16537718 DOI: 10.1158/1055-9965.Epi-05-0542 |
0.318 |
|
| 2006 |
Linford NJ, Schriner SE, Rabinovitch PS. Oxidative damage and aging: spotlight on mitochondria. Cancer Research. 66: 2497-9. PMID 16510562 DOI: 10.1158/0008-5472.Can-05-3163 |
0.339 |
|
| 2005 |
Wolf N, Penn P, Pendergrass W, Van Remmen H, Bartke A, Rabinovitch P, Martin GM. Age-related cataract progression in five mouse models for anti-oxidant protection or hormonal influence. Experimental Eye Research. 81: 276-85. PMID 16129095 DOI: 10.1016/J.Exer.2005.01.024 |
0.34 |
|
| 2005 |
Schriner SE, Linford NJ, Martin GM, Treuting P, Ogburn CE, Emond M, Coskun PE, Ladiges W, Wolf N, Van Remmen H, Wallace DC, Rabinovitch PS. Extension of murine life span by overexpression of catalase targeted to mitochondria. Science (New York, N.Y.). 308: 1909-11. PMID 15879174 DOI: 10.1126/Science.1106653 |
0.363 |
|
| 2005 |
Potter AJ, Rabinovitch PS. The cell cycle phases of DNA damage and repair initiated by topoisomerase II-targeting chemotherapeutic drugs. Mutation Research. 572: 27-44. PMID 15790488 DOI: 10.1016/J.Mrfmmm.2004.11.018 |
0.764 |
|
| 2004 |
Poot M, Jin X, Hill JP, Gollahon KA, Rabinovitch PS. Distinct functions for WRN and TP53 in a shared pathway of cellular response to 1-beta-D-arabinofuranosylcytosine and bleomycin. Experimental Cell Research. 296: 327-36. PMID 15149862 DOI: 10.1016/J.Yexcr.2004.02.011 |
0.319 |
|
| 2004 |
Blank A, Bobola MS, Gold B, Varadarajan S, D Kolstoe D, Meade EH, Rabinovitch PS, Loeb LA, Silber JR. The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function. Dna Repair. 3: 629-38. PMID 15135730 DOI: 10.1016/J.Dnarep.2004.02.003 |
0.305 |
|
| 2003 |
Palanca-Wessels MC, Klingelhutz A, Reid BJ, Norwood TH, Opheim KE, Paulson TG, Feng Z, Rabinovitch PS. Extended lifespan of Barrett's esophagus epithelium transduced with the human telomerase catalytic subunit: a useful in vitro model. Carcinogenesis. 24: 1183-90. PMID 12807723 DOI: 10.1093/Carcin/Bgg076 |
0.302 |
|
| 2002 |
Poot M, Gollahon KA, Emond MJ, Silber JR, Rabinovitch PS. Werner syndrome diploid fibroblasts are sensitive to 4-nitroquinoline-N-oxide and 8-methoxypsoralen: implications for the disease phenotype. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 757-8. PMID 11978740 DOI: 10.1096/Fj.01-0906Fje |
0.305 |
|
| 2002 |
Potter AJ, Gollahon KA, Palanca BJ, Harbert MJ, Choi YM, Moskovitz AH, Potter JD, Rabinovitch PS. Flow cytometric analysis of the cell cycle phase specificity of DNA damage induced by radiation, hydrogen peroxide and doxorubicin. Carcinogenesis. 23: 389-401. PMID 11895853 DOI: 10.1093/Carcin/23.3.389 |
0.761 |
|
| 2001 |
Rosato MT, Jabbour AJ, Ponce RA, Kavanagh TJ, Takaro TK, Hill JP, Poot M, Rabinovitch PS, Faustman EM. Simultaneous analysis of surface marker expression and cell cycle progression in human peripheral blood mononuclear cells. Journal of Immunological Methods. 256: 35-46. PMID 11516753 DOI: 10.1016/S0022-1759(01)00428-8 |
0.327 |
|
| 2001 |
Oshima J, Martin GM, Gray MD, Poot M, Rabinovitch PS. Gene action at the werner helicase locus: its role in the pathobiology of aging Advances in Cell Aging and Gerontology. 4: 207-226. DOI: 10.1016/S1566-3124(01)04034-2 |
0.301 |
|
| 2000 |
Pierce RH, Campbell JS, Stephenson AB, Franklin CC, Chaisson M, Poot M, Kavanagh TJ, Rabinovitch PS, Fausto N. Disruption of redox homeostasis in tumor necrosis factor-induced apoptosis in a murine hepatocyte cell line. The American Journal of Pathology. 157: 221-36. PMID 10880392 DOI: 10.1016/S0002-9440(10)64533-6 |
0.328 |
|
| 1999 |
Potter A, Kim C, Gollahon KA, Rabinovitch PS. Apoptotic human lymphocytes have diminished CD4 and CD8 receptor expression. Cellular Immunology. 193: 36-47. PMID 10202111 DOI: 10.1006/Cimm.1998.1443 |
0.752 |
|
| 1999 |
Poot M, Gollahon KA, Rabinovitch PS. Werner syndrome lymphoblastoid cells are sensitive to camptothecin-induced apoptosis in S-phase. Human Genetics. 104: 10-4. PMID 10071186 DOI: 10.1007/S004390050903 |
0.33 |
|
| 1998 |
Ogburn CE, Austad SN, Holmes DJ, Kiklevich JV, Gollahon K, Rabinovitch PS, Martin GM. Cultured renal epithelial cells from birds and mice: enhanced resistance of avian cells to oxidative stress and DNA damage. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 53: B287-92. PMID 18314559 DOI: 10.1093/Gerona/53A.4.B287 |
0.337 |
|
| 1997 |
Potter AJ, Grossmann A, Rabinovitch PS, Eaton DL, Kavanagh TJ. The effect of in vitro phorone exposure on glutathione content and T cell antigen receptor (CD3)-stimulated calcium mobilization in murine splenic T lymphocytes. Toxicology in Vitro : An International Journal Published in Association With Bibra. 11: 355-63. PMID 20654322 DOI: 10.1016/S0887-2333(97)82756-7 |
0.753 |
|
| 1997 |
Taylor CG, Potter AJ, Rabinovitch PS. Splenocyte glutathione and CD3-mediated cell proliferation are reduced in mice fed a protein-deficient diet. The Journal of Nutrition. 127: 44-50. PMID 9040542 DOI: 10.1093/Jn/127.1.44 |
0.764 |
|
| 1996 |
Glogovac JK, Porter PL, Banker DE, Rabinovitch PS. Cytokeratin labeling of breast cancer cells extracted from paraffin-embedded tissue for bivariate flow cytometric analysis. Cytometry. 24: 260-7. PMID 8800559 DOI: 10.1002/(Sici)1097-0320(19960701)24:3<260::Aid-Cyto9>3.0.Co;2-L |
0.3 |
|
| 1996 |
Lohmiller JJ, Roellich KM, Toledano A, Rabinovitch PS, Wolf NS, Grossmann A. Aged murine T-lymphocytes are more resistant to oxidative damage due to the predominance of the cells possessing the memory phenotype. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 51: B132-40. PMID 8612097 DOI: 10.1093/Gerona/51A.2.B132 |
0.327 |
|
| 1995 |
Grossmann A, Rabinovitch PS, Kavanagh TJ, Jinneman JC, Gilliland LK, Ledbetter JA, Kanner SB. Activation of murine T-cells via phospholipase-C gamma 1-associated protein tyrosine phosphorylation is reduced with aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 50: B205-12. PMID 7614232 DOI: 10.1093/Gerona/50A.4.B205 |
0.316 |
|
| 1995 |
Poot M, Teubert H, Rabinovitch PS, Kavanagh TJ. De novo synthesis of glutathione is required for both entry into and progression through the cell cycle Journal of Cellular Physiology. 163: 555-560. PMID 7539813 DOI: 10.1002/Jcp.1041630316 |
0.306 |
|
| 1994 |
Kavanagh TJ, Raghu G, White CC, Martin GM, Rabinovitch PS, Eaton DL. Enhancement of glutathione content in glutathione synthetase-deficient fibroblasts from a patient with 5-oxoprolinuria via metabolic cooperation with normal fibroblasts. Experimental Cell Research. 212: 69-76. PMID 7909755 DOI: 10.1006/Excr.1994.1119 |
0.314 |
|
| 1993 |
Kavanagh TJ, Grossmann A, Jinneman JC, Kanner SB, White CC, Eaton DL, Ledbetter JA, Rabinovitch PS. The effect of 1-chloro-2,4-dinitrobenzene exposure on antigen receptor (CD3)-stimulated transmembrane signal transduction in purified subsets of human peripheral blood lymphocytes. Toxicology and Applied Pharmacology. 119: 91-9. PMID 8470127 DOI: 10.1006/Taap.1993.1047 |
0.312 |
|
| 1992 |
Kanner SB, Kavanagh TJ, Grossmann A, Hu SL, Bolen JB, Rabinovitch PS, Ledbetter JA. Sulfhydryl oxidation down-regulates T-cell signaling and inhibits tyrosine phosphorylation of phospholipase Cγ1 Proceedings of the National Academy of Sciences of the United States of America. 89: 300-304. PMID 1370350 DOI: 10.1073/Pnas.89.1.300 |
0.302 |
|
| 1991 |
Grossmann A, Maggio-Price L, Jinneman JC, Rabinovitch PS. Influence of aging on intracellular free calcium and proliferation of mouse T-cell subsets from various lymphoid organs. Cellular Immunology. 135: 118-31. PMID 1826862 DOI: 10.1016/0008-8749(91)90259-E |
0.333 |
|
| 1991 |
Levine DS, Sanchez CA, Rabinovitch PS, Reid BJ. Formation of the tetraploid intermediate is associated with the development of cells with more than four centrioles in the elastase-simian virus 40 tumor antigen transgenic mouse model of pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America. 88: 6427-31. PMID 1650467 DOI: 10.1073/Pnas.88.15.6427 |
0.308 |
|
| 1990 |
Grossmann A, Ledbetter JA, Rabinovitch PS. Aging-related deficiency in intracellular calcium response to anti-CD3 or concanavalin A in murine T-cell subsets. Journal of Gerontology. 45: B81-6. PMID 2139884 DOI: 10.1093/Geronj/45.3.B81 |
0.331 |
|
| 1990 |
Grossmann A, Maggio-Price L, Jinneman JC, Wolf NS, Rabinovitch PS. The effect of long-term caloric restriction on function of T-cell subsets in old mice. Cellular Immunology. 131: 191-204. PMID 2121372 DOI: 10.1016/0008-8749(90)90246-N |
0.334 |
|
| 1990 |
Kavanagh TJ, Grossmann A, Jaecks EP, Jinneman JC, Eaton DL, Martin GM, Rabinovitch PS. Proliferative capacity of human peripheral blood lymphocytes sorted on the basis of glutathione content Journal of Cellular Physiology. 145: 472-480. PMID 1703168 DOI: 10.1002/Jcp.1041450312 |
0.323 |
|
| 1990 |
Poot M, Koehler J, Rabinovitch PS, Hoehn H, Priest JH. Cell kinetic disturbances induced by treatment of human diploid fibroblasts with 5-azacytidine indicate a major role for DNA methylation in the regulation of the chromosome cycle. Human Genetics. 84: 258-262. PMID 1689269 DOI: 10.1007/Bf00200571 |
0.317 |
|
| 1988 |
Kavanagh TJ, Martin GM, Livesey JC, Rabinovitch PS. Direct evidence of intercellular sharing of glutathione via metabolic cooperation Journal of Cellular Physiology. 137: 353-359. PMID 3192619 DOI: 10.1002/Jcp.1041370220 |
0.31 |
|
| 1988 |
Poot M, Schindler D, Kubbies M, Hoehn H, Rabinovitch PS. Bromodeoxyuridine amplifies the inhibitory effect of oxygen on cell proliferation. Cytometry. 9: 332-8. PMID 2456899 DOI: 10.1002/Cyto.990090410 |
0.301 |
|
| 1984 |
Burmer GC, Rabinovitch PS, Norwood TH. Evidence for differences in the mechanism of cell cycle arrest between senescent and serum-deprived human fibroblasts: heterokaryon and metabolic inhibitor studies. Journal of Cellular Physiology. 118: 97-103. PMID 6690456 DOI: 10.1002/Jcp.1041180116 |
0.311 |
|
| 1982 |
Pendergrass WR, Saulewicz AC, Burmer GC, Rabinovitch PS, Norwood TH, Martin GM. Evidence that a critical threshold of DNA polymerase-alpha activity may be required for the initiation of DNA synthesis in mammalian cell heterokaryons. Journal of Cellular Physiology. 113: 141-51. PMID 7130287 DOI: 10.1002/Jcp.1041130123 |
0.313 |
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