| Year |
Citation |
Score |
| 2023 |
Heydenreich FM, Marti-Solano M, Sandhu M, Kobilka BK, Bouvier M, Babu MM. Molecular determinants of ligand efficacy and potency in GPCR signaling. Science (New York, N.Y.). 382: eadh1859. PMID 38127743 DOI: 10.1126/science.adh1859 |
0.849 |
|
| 2023 |
Lefkowitz RJ, Rockman HA, Shim PJ, Liu S, Ahn S, Pani B, Rajagopal S, Shenoy SK, Bouvier M, Benovic JL, Liggett SB, Ruffolo RR, Bristow MR, Packer M. How carvedilol does not activate β-adrenoceptors. Nature Communications. 14: 7866. PMID 38036531 DOI: 10.1038/s41467-023-42848-5 |
0.779 |
|
| 2023 |
Wright SC, Motso A, Koutsilieri S, Beusch CM, Sabatier P, Berghella A, Blondel-Tepaz É, Mangenot K, Pittarokoilis I, Sismanoglou DC, Le Gouill C, Olsen JV, Zubarev RA, Lambert NA, Hauser AS, ... Bouvier M, et al. GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics. Nature Communications. 14: 6243. PMID 37813859 DOI: 10.1038/s41467-023-41893-4 |
0.775 |
|
| 2023 |
Burghi V, Paradis JS, Officer A, Adame-Garcia SR, Wu X, Matthees ESF, Barsi-Rhyne B, Ramms DJ, Clubb L, Acosta M, Tamayo P, Bouvier M, Inoue A, von Zastrow M, Hoffmann C, et al. Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor. The Journal of Biological Chemistry. 299: 105293. PMID 37774973 DOI: 10.1016/j.jbc.2023.105293 |
0.836 |
|
| 2023 |
Kaur S, Sokrat B, Capozzi ME, El K, Bai Y, Jazic A, Han B, Krishnakumar K, D'Alessio DA, Campbell JE, Bouvier M, Shenoy SK. The Ubiquitination Status of the Glucagon Receptor determines Signal Bias. The Journal of Biological Chemistry. 104690. PMID 37037304 DOI: 10.1016/j.jbc.2023.104690 |
0.703 |
|
| 2022 |
Ehrlich AT, Couvineau P, Schamiloglu S, Wojcik S, Da Fonte D, Mezni A, von Zastrow M, Bender KJ, Bouvier M, Kieffer BL. Visualization of real-time receptor endocytosis in dopamine neurons enabled by NTSR1-Venus knock-in mice. Frontiers in Cellular Neuroscience. 16: 1076599. PMID 36523815 DOI: 10.3389/fncel.2022.1076599 |
0.81 |
|
| 2022 |
Sénéchal C, Fujita R, Jamet S, Maiga A, Dort J, Orfi Z, Dumont NA, Bouvier M, Crist C. The adhesion G-protein-coupled receptor Gpr116 is essential to maintain the skeletal muscle stem cell pool. Cell Reports. 41: 111645. PMID 36384129 DOI: 10.1016/j.celrep.2022.111645 |
0.358 |
|
| 2022 |
Paradis JS, Feng X, Murat B, Jefferson RE, Sokrat B, Szpakowska M, Hogue M, Bergkamp ND, Heydenreich FM, Smit MJ, Chevigné A, Bouvier M, Barth P. Computationally designed GPCR quaternary structures bias signaling pathway activation. Nature Communications. 13: 6826. PMID 36369272 DOI: 10.1038/s41467-022-34382-7 |
0.861 |
|
| 2022 |
Lupisella J, St-Onge S, Carrier M, Cook EM, Wang T, Sum C, Fernando G, Apgar K, Zhang R, Carson N, Snyder BJ, Ryan CS, Ma X, Dierks EA, Little S, ... ... Bouvier M, et al. Molecular Mechanisms of Desensitization Underlying the Differential Effects of Formyl Peptide Receptor 2 Agonists on Cardiac Structure-Function Post Myocardial Infarction. Acs Pharmacology & Translational Science. 5: 892-906. PMID 36268126 DOI: 10.1021/acsptsci.2c00042 |
0.834 |
|
| 2022 |
Fink EA, Xu J, Hübner H, Braz JM, Seemann P, Avet C, Craik V, Weikert D, Schmidt MF, Webb CM, Tolmachova NA, Moroz YS, Huang XP, Kalyanaraman C, Gahbauer S, ... ... Bouvier M, et al. Structure-based discovery of nonopioid analgesics acting through the α-adrenergic receptor. Science (New York, N.Y.). 377: eabn7065. PMID 36173843 DOI: 10.1126/science.abn7065 |
0.831 |
|
| 2022 |
Reynaud S, Laurin SA, Ciolek J, Barbe P, Van Baelen AC, Susset M, Blondel F, Ghazarian M, Boeri J, Vanden Driessche M, Upert G, Mourier G, Kessler P, Konnert L, Beroud R, ... ... Bouvier M, et al. From a Cone Snail Toxin to a Competitive MC4R Antagonist. Journal of Medicinal Chemistry. 65: 12084-12094. PMID 36063022 DOI: 10.1021/acs.jmedchem.2c00786 |
0.809 |
|
| 2022 |
Plouffe B, Karamitri A, Flock T, Gallion JM, Houston S, Daly CA, Bonnefond A, Guillaume JL, Le Gouill C, Froguel P, Lichtarge O, Deupi X, Jockers R, Bouvier M. Structural Elements Directing G Proteins and β-Arrestin Interactions with the Human Melatonin Type 2 Receptor Revealed by Natural Variants. Acs Pharmacology & Translational Science. 5: 89-101. PMID 35846981 DOI: 10.1021/acsptsci.1c00239 |
0.774 |
|
| 2022 |
Heydenreich FM, Plouffe B, Rizk A, Milic D, Zhou J, Breton B, Le Gouill C, Inoue A, Bouvier M, Veprintsev D. . Molecular Pharmacology. PMID 35779859 DOI: 10.1124/molpharm.122.000497 |
0.844 |
|
| 2022 |
Priestley ES, Banville J, Deon D, Dubé L, Gagnon M, Guy J, Lapointe P, Lavallée JF, Martel A, Plamondon S, Rémillard R, Ruediger E, Tremblay F, Posy SL, Guarino VR, ... ... Bouvier M, et al. Discovery of Two Novel Antiplatelet Clinical Candidates (BMS-986120 and BMS-986141) That Antagonize Protease-Activated Receptor 4. Journal of Medicinal Chemistry. PMID 35729784 DOI: 10.1021/acs.jmedchem.2c00359 |
0.315 |
|
| 2022 |
Hedderich JB, Persechino M, Becker K, Heydenreich FM, Gutermuth T, Bouvier M, Bünemann M, Kolb P. The pocketome of G-protein-coupled receptors reveals previously untargeted allosteric sites. Nature Communications. 13: 2567. PMID 35538063 DOI: 10.1038/s41467-022-29609-6 |
0.818 |
|
| 2022 |
Hauser AS, Avet C, Normand C, Mancini A, Inoue A, Bouvier M, Gloriam DE. Common coupling map advances GPCR-G protein selectivity. Elife. 11. PMID 35302494 DOI: 10.7554/eLife.74107 |
0.842 |
|
| 2022 |
Avet C, Mancini A, Breton B, Le Gouill C, Hauser AS, Normand C, Kobayashi H, Gross F, Hogue M, Lukasheva V, St-Onge S, Carrier M, Héroux M, Morissette S, Fauman EB, ... ... Bouvier M, et al. Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs. Elife. 11. PMID 35302493 DOI: 10.7554/eLife.74101 |
0.844 |
|
| 2022 |
Kolb P, Kenakin T, Alexander SPH, Bermudez M, Bohn LM, Breinholt CS, Bouvier M, Hill SJ, Kostenis E, Martemyanov K, Neubig RR, Onaran HO, Rajagopal S, Roth BL, Selent J, et al. Community Guidelines for GPCR Ligand Bias: IUPHAR Review XX. British Journal of Pharmacology. PMID 35106752 DOI: 10.1111/bph.15811 |
0.699 |
|
| 2022 |
Tran K, Sainsily X, Côté J, Coquerel D, Couvineau P, Saibi S, Haroune L, Besserer-Offroy É, Flynn-Robitaille J, Resua Rojas M, Murza A, Longpré JM, Auger-Messier M, Lesur O, Bouvier M, et al. Size-Reduced Macrocyclic Analogues of [Pyr]-apelin-13 Showing Negative Gα Bias Still Produce Prolonged Cardiac Effects. Journal of Medicinal Chemistry. 65: 531-551. PMID 34982553 DOI: 10.1021/acs.jmedchem.1c01708 |
0.755 |
|
| 2022 |
Duarte DA, Parreiras-E-Silva LT, Oliveira EB, Bouvier M, Costa-Neto CM. Angiotensin II Type 1 Receptor Tachyphylaxis Is Defined by Agonist Residence Time. Hypertension (Dallas, Tex. : 1979). 79: 115-125. PMID 34739768 DOI: 10.1161/HYPERTENSIONAHA.121.17977 |
0.437 |
|
| 2021 |
Hauser AS, Kooistra AJ, Munk C, Heydenreich FM, Veprintsev DB, Bouvier M, Babu MM, Gloriam DE. GPCR activation mechanisms across classes and macro/microscales. Nature Structural & Molecular Biology. 28: 879-888. PMID 34759375 DOI: 10.1038/s41594-021-00674-7 |
0.8 |
|
| 2021 |
Pereira PHS, Garcia CRS, Bouvier M. Identifying Plasmodium falciparum receptor activation using bioluminescence resonance energy transfer (BRET)-based biosensors in HEK293 cells. Methods in Cell Biology. 166: 223-233. PMID 34752334 DOI: 10.1016/bs.mcb.2021.06.018 |
0.307 |
|
| 2021 |
Hegron A, Huh E, Deupi X, Sokrat B, Gao W, Le Gouill C, Canouil M, Boissel M, Charpentier G, Roussel R, Balkau B, Froguel P, Plouffe B, Bonnefond A, Lichtarge O, ... ... Bouvier M, et al. Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants. Acs Pharmacology & Translational Science. 4: 1614-1627. PMID 34661078 DOI: 10.1021/acsptsci.1c00157 |
0.838 |
|
| 2021 |
Mansour A, Nagi K, Dallaire P, Lukasheva V, Le Gouill C, Bouvier M, Pineyro G. Comprehensive Signaling Profiles Reveal Unsuspected Functional Selectivity of δ-Opioid Receptor Agonists and Allow the Identification of Ligands with the Greatest Potential for Inducing Cyclase Superactivation. Acs Pharmacology & Translational Science. 4: 1483-1498. PMID 34661070 DOI: 10.1021/acsptsci.1c00019 |
0.725 |
|
| 2021 |
Ehrlich AT, Semache M, Couvineau P, Wojcik S, Kobayashi H, Thelen M, Gross F, Hogue M, Le Gouill C, Darcq E, Bouvier M, Kieffer BL. Ackr3-Venus knock-in mouse lights up brain vasculature. Molecular Brain. 14: 151. PMID 34583741 DOI: 10.1186/s13041-021-00862-y |
0.847 |
|
| 2021 |
Stepniewski TM, Mancini A, Ågren R, Torrens-Fontanals M, Semache M, Bouvier M, Sahlholm K, Breton B, Selent J. Mechanistic insights into dopaminergic and serotonergic neurotransmission - concerted interactions with helices 5 and 6 drive the functional outcome. Chemical Science. 12: 10990-11003. PMID 34522296 DOI: 10.1039/d1sc00749a |
0.848 |
|
| 2021 |
Budzinski J, Maschauer S, Kobayashi H, Couvineau P, Vogt H, Gmeiner P, Roggenhofer A, Prante O, Bouvier M, Weikert D. Bivalent ligands promote endosomal trafficking of the dopamine D3 receptor-neurotensin receptor 1 heterodimer. Communications Biology. 4: 1062. PMID 34508168 DOI: 10.1038/s42003-021-02574-4 |
0.822 |
|
| 2021 |
García RA, Lupisella JA, Ito BR, Hsu MY, Fernando G, Carson NL, Allocco JJ, Ryan CS, Zhang R, Wang Z, Heroux M, Carrier M, St-Onge S, Bouvier M, Dudhgaonkar S, et al. Selective FPR2 Agonism Promotes a Proresolution Macrophage Phenotype and Improves Cardiac Structure-Function Post Myocardial Infarction. Jacc. Basic to Translational Science. 6: 676-689. PMID 34466754 DOI: 10.1016/j.jacbts.2021.07.007 |
0.808 |
|
| 2021 |
Giubilaro J, Schuetz DA, Stepniewski TM, Namkung Y, Khoury E, Lara-Márquez M, Campbell S, Beautrait A, Armando S, Radresa O, Duchaine J, Lamarche-Vane N, Claing A, Selent J, Bouvier M, et al. Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen. Nature Communications. 12: 4688. PMID 34344896 DOI: 10.1038/s41467-021-24968-y |
0.849 |
|
| 2021 |
Xu L, Chen B, Schihada H, Wright SC, Turku A, Wu Y, Han GW, Kowalski-Jahn M, Kozielewicz P, Bowin CF, Zhang X, Li C, Bouvier M, Schulte G, Xu F. Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric G. Cell Research. PMID 34239071 DOI: 10.1038/s41422-021-00525-6 |
0.723 |
|
| 2021 |
Trauelsen M, Hiron TK, Lin D, Petersen JE, Breton B, Husted AS, Hjorth SA, Inoue A, Frimurer TM, Bouvier M, O'Callaghan CA, Schwartz TW. Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling. Cell Reports. 35: 109246. PMID 34133934 DOI: 10.1016/j.celrep.2021.109246 |
0.767 |
|
| 2021 |
Wright SC, Bouvier M. Illuminating the complexity of GPCR pathway selectivity - advances in biosensor development. Current Opinion in Structural Biology. 69: 142-149. PMID 34048988 DOI: 10.1016/j.sbi.2021.04.006 |
0.793 |
|
| 2021 |
Wright SC, Lukasheva V, Le Gouill C, Kobayashi H, Breton B, Mailhot-Larouche S, Blondel-Tepaz É, Antunes Vieira N, Costa-Neto C, Héroux M, Lambert NA, Parreiras-E-Silva LT, Bouvier M. BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated G activation at early endosomes. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33990469 DOI: 10.1073/pnas.2025846118 |
0.845 |
|
| 2021 |
Meyrath M, Palmer CB, Reynders N, Vanderplasschen A, Ollert M, Bouvier M, Szpakowska M, Chevigné A. Proadrenomedullin N-Terminal 20 Peptides (PAMPs) Are Agonists of the Chemokine Scavenger Receptor ACKR3/CXCR7. Acs Pharmacology & Translational Science. 4: 813-823. PMID 33860204 DOI: 10.1021/acsptsci.1c00006 |
0.437 |
|
| 2021 |
Brouwers B, de Oliveira EM, Marti-Solano M, Monteiro FBF, Laurin SA, Keogh JM, Henning E, Bounds R, Daly CA, Houston S, Ayinampudi V, Wasiluk N, Clarke D, Plouffe B, Bouvier M, et al. Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation. Cell Reports. 34: 108862. PMID 33761344 DOI: 10.1016/j.celrep.2021.108862 |
0.8 |
|
| 2021 |
Gargalovic P, Wong P, Onorato J, Finlay H, Wang T, Yan M, Crain E, St-Onge S, Héroux M, Bouvier M, Xu C, Chen XQ, Generaux C, Lawrence M, Wexler R, et al. In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure. Circulation. Heart Failure. CIRCHEARTFAILURE1200. PMID 33663236 DOI: 10.1161/CIRCHEARTFAILURE.120.007351 |
0.792 |
|
| 2021 |
Blondel-Tepaz E, Leverve M, Sokrat B, Paradis JS, Kosic M, Saha K, Auffray C, Lima-Fernandes E, Zamborlini A, Poupon A, Gaboury L, Findlay J, Baillie GS, Enslen H, Bouvier M, et al. The RanBP2/RanGAP1-SUMO complex gates β-arrestin2 nuclear entry to regulate the Mdm2-p53 signaling axis. Oncogene. PMID 33649538 DOI: 10.1038/s41388-021-01704-w |
0.786 |
|
| 2021 |
Tschaikner P, Regele D, Röck R, Salvenmoser W, Meyer D, Bouvier M, Geley S, Stefan E, Aanstad P. Feedback Control of the Gpr161-G-PKA axis contributes to basal Hedgehog repression in zebrafish. Development (Cambridge, England). PMID 33531430 DOI: 10.1242/dev.192443 |
0.36 |
|
| 2021 |
Trân K, Van Den Hauwe R, Sainsily X, Couvineau P, Côté J, Simard L, Echevarria M, Murza A, Serre A, Théroux L, Saibi S, Haroune L, Longpré JM, Lesur O, Auger-Messier M, ... ... Bouvier M, et al. Constraining the Side Chain of C-Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile. Journal of Medicinal Chemistry. PMID 33524256 DOI: 10.1021/acs.jmedchem.0c01941 |
0.756 |
|
| 2021 |
René P, Lanfray D, Richard D, Bouvier M. Pharmacological chaperone action in humanized mouse models of MC4R-linked obesity. Jci Insight. PMID 33434184 DOI: 10.1172/jci.insight.132778 |
0.793 |
|
| 2020 |
Simões SC, Balico-Silva AL, Parreiras-E-Silva LT, Bitencourt ALB, Bouvier M, Costa-Neto CM. Signal Transduction Profiling of Angiotensin II Type 1 Receptor With Mutations Associated to Atrial Fibrillation in Humans. Frontiers in Pharmacology. 11: 600132. PMID 33424609 DOI: 10.3389/fphar.2020.600132 |
0.363 |
|
| 2020 |
Simões SC, Balico-Silva AL, Parreiras-E-Silva LT, Bitencourt ALB, Bouvier M, Costa-Neto CM. Signal Transduction Profiling of Angiotensin II Type 1 Receptor With Mutations Associated to Atrial Fibrillation in Humans. Frontiers in Pharmacology. 11: 600132. PMID 33424609 DOI: 10.3389/fphar.2020.600132 |
0.363 |
|
| 2020 |
Trân K, Murza A, Sainsily X, Delile E, Couvineau P, Côté J, Coquerel D, Peloquin M, Auger-Messier M, Bouvier M, Lesur O, Sarret P, Marsault É. Structure-Activity Relationship and Bioactivity of Short Analogues of ELABELA as Agonists of the Apelin Receptor. Journal of Medicinal Chemistry. PMID 33350824 DOI: 10.1021/acs.jmedchem.0c01547 |
0.812 |
|
| 2020 |
Latorraca NR, Masureel M, Hollingsworth SA, Heydenreich FM, Suomivuori CM, Brinton C, Townshend RJL, Bouvier M, Kobilka BK, Dror RO. How GPCR Phosphorylation Patterns Orchestrate Arrestin-Mediated Signaling. Cell. PMID 33296703 DOI: 10.1016/j.cell.2020.11.014 |
0.818 |
|
| 2020 |
Avet C, Sturino C, Grastilleur S, Gouill CL, Semache M, Gross F, Gendron L, Bennani Y, Mancini JA, Sayegh CE, Bouvier M. The PAR2 inhibitor I-287 selectively targets Gα and Gα signaling and has anti-inflammatory effects. Communications Biology. 3: 719. PMID 33247181 DOI: 10.1038/s42003-020-01453-8 |
0.815 |
|
| 2020 |
Imam A, Winnebeck EC, Buchholz N, Froguel P, Bonnefond A, Solimena M, Ivanova A, Bouvier M, Plouffe B, Charpentier G, Karamitri A, Jockers R, Roenneberg T, Vetter C. Circadian, Sleep and Caloric Intake Phenotyping in Type 2 Diabetes Patients With Rare Melatonin Receptor 2 Mutations and Controls: A Pilot Study. Frontiers in Physiology. 11: 564140. PMID 33162895 DOI: 10.3389/fphys.2020.564140 |
0.678 |
|
| 2020 |
Møller TC, Pedersen MF, van Senten JR, Seiersen SD, Mathiesen JM, Bouvier M, Bräuner-Osborne H. Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells. Scientific Reports. 10: 17395. PMID 33060647 DOI: 10.1038/s41598-020-73674-0 |
0.377 |
|
| 2020 |
Sundqvist M, Holdfeldt A, Wright SC, Møller TC, Siaw E, Jennbacken K, Franzyk H, Bouvier M, Dahlgren C, Forsman H. Barbadin selectively modulates FPR2-mediated neutrophil functions independent of receptor endocytosis. Biochimica Et Biophysica Acta. Molecular Cell Research. 118849. PMID 32916203 DOI: 10.1016/J.Bbamcr.2020.118849 |
0.786 |
|
| 2020 |
Okashah N, Wright SC, Kawakami K, Mathiasen S, Zhou J, Lu S, Javitch JA, Inoue A, Bouvier M, Lambert NA. Agonist-induced formation of unproductive receptor-G complexes. Proceedings of the National Academy of Sciences of the United States of America. PMID 32817560 DOI: 10.1073/Pnas.2003787117 |
0.845 |
|
| 2020 |
Lukasheva V, Devost D, Le Gouill C, Namkung Y, Martin RD, Longpré JM, Amraei M, Shinjo Y, Hogue M, Lagacé M, Breton B, Aoki J, Tanny JC, Laporte SA, Pineyro G, ... ... Bouvier M, et al. Signal profiling of the βAR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by βAR and βAR. Scientific Reports. 10: 8779. PMID 32471984 DOI: 10.1038/S41598-020-65636-3 |
0.828 |
|
| 2020 |
Baidya M, Kumari P, Dwivedi-Agnihotri H, Pandey S, Sokrat B, Sposini S, Chaturvedi M, Srivastava A, Roy D, Hanyaloglu AC, Bouvier M, Shukla AK. Genetically encoded intrabody sensors report the interaction and trafficking of β-arrestin 1 upon activation of G protein-coupled receptors. The Journal of Biological Chemistry. PMID 32439801 DOI: 10.1074/Jbc.Ra120.013470 |
0.849 |
|
| 2020 |
Nourreddine S, Lavoie G, Paradis J, Ben El Kadhi K, Méant A, Aubert L, Grondin B, Gendron P, Chabot B, Bouvier M, Carreno S, Roux PP. NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay. Cell Reports. 31: 107660. PMID 32433969 DOI: 10.1016/J.Celrep.2020.107660 |
0.775 |
|
| 2020 |
Benredjem B, Gallion J, Pelletier D, Dallaire P, Charbonneau J, Cawkill D, Nagi K, Gosink M, Lukasheva V, Jenkinson S, Ren Y, Somps C, Murat B, Van Der Westhuizen E, Le Gouill C, ... ... Bouvier M, et al. Author Correction: Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response. Nature Communications. 11: 1929. PMID 32300106 DOI: 10.1038/S41467-020-15945-Y |
0.785 |
|
| 2020 |
Alexander RA, Lot I, Saha K, Abadie G, Lambert M, Decosta E, Kobayashi H, Beautrait A, Borrull A, Asnacios A, Bouvier M, Scott MGH, Marullo S, Enslen H. Beta-arrestins operate an on/off control switch for focal adhesion kinase activity. Cellular and Molecular Life Sciences : Cmls. PMID 32040695 DOI: 10.1007/S00018-020-03471-5 |
0.836 |
|
| 2020 |
Imam A, Winnebeck EC, Buchholz N, Froguel P, Bonnefond A, Solimena M, Ivanova A, Bouvier M, Plouffe B, Charpentier G, Karamitri A, Jockers R, Roenneberg T, Vetter C. Circadian, Sleep and Caloric Intake Phenotyping in Type 2 Diabetes Patients With Rare Melatonin Receptor 2 Mutations and Controls: A Pilot Study Frontiers in Physiology. 11. DOI: 10.3389/fphys.2020.564140 |
0.691 |
|
| 2020 |
Mancini A, Avet C, Breton B, Normand C, Gross F, Lukasheva V, Hogue M, Morissette S, Fauman E, Fortin J, Schann S, Gouill CL, Bouvier M. Profiling the Signaling Repertoire of One Hundred Therapeutically‐Relevant Human GPCRs The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05196 |
0.797 |
|
| 2019 |
Picard LP, Schonegge AM, Bouvier M. Structural Insight into G Protein-Coupled Receptor Signaling Efficacy and Bias between Gs and β-Arrestin. Acs Pharmacology & Translational Science. 2: 148-154. PMID 32259053 DOI: 10.1021/acsptsci.9b00012 |
0.848 |
|
| 2019 |
García RA, Ito BR, Lupisella JA, Carson NA, Hsu MY, Fernando G, Heroux M, Bouvier M, Dierks E, Kick EK, Gordon DA, Chen J, Mintier G, Carrier M, St-Onge S, et al. Preservation of Post-Infarction Cardiac Structure and Function via Long-Term Oral Formyl Peptide Receptor Agonist Treatment. Jacc. Basic to Translational Science. 4: 905-920. PMID 31909300 DOI: 10.1016/J.Jacbts.2019.07.005 |
0.802 |
|
| 2019 |
Benredjem B, Gallion J, Pelletier D, Dallaire P, Charbonneau J, Cawkill D, Nagi K, Gosink M, Lukasheva V, Jenkinson S, Ren Y, Somps C, Murat B, Van Der Westhuizen E, Le Gouill C, ... ... Bouvier M, et al. Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response. Nature Communications. 10: 4075. PMID 31501422 DOI: 10.1038/S41467-019-11875-6 |
0.825 |
|
| 2019 |
Pedersen MF, Wróbel TM, Märcher-Rørsted E, Pedersen DS, Møller TC, Gabriele F, Pedersen H, Matosiuk D, Foster SR, Bouvier M, Bräuner-Osborne H. Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics. Neuropharmacology. 107718. PMID 31351108 DOI: 10.1016/J.Neuropharm.2019.107718 |
0.458 |
|
| 2019 |
Miller MM, Banville J, Friends T, Gagnon M, Hangeland JJ, Lavalee JF, Martel A, O'Grady H, Remillard R, Ruediger EH, Tremblay F, Posy S, Allegretto N, Guarino VR, Harden D, ... ... Bouvier M, et al. Discovery of Potent Protease-Activated Receptor 4 Antagonists with in vivo Antithrombotic Efficacy. Journal of Medicinal Chemistry. PMID 31246024 DOI: 10.1021/Acs.Jmedchem.9B00186 |
0.336 |
|
| 2019 |
Wang W, Shen M, Fischer C, Basu R, Hazra S, Couvineau P, Paul M, Wang F, Toth S, Mix DS, Poglitsch M, Gerard NP, Bouvier M, Vederas JC, Penninger JM, et al. Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs. Proceedings of the National Academy of Sciences of the United States of America. PMID 31189595 DOI: 10.1073/Pnas.1900152116 |
0.747 |
|
| 2019 |
Stanek M, Picard LP, Schmidt MF, Kaindl JM, Hübner H, Bouvier M, Weikert D, Gmeiner P. Hybridization of β-adrenergic agonists and antagonists confers G protein bias. Journal of Medicinal Chemistry. PMID 31042379 DOI: 10.1021/Acs.Jmedchem.9B00349 |
0.825 |
|
| 2019 |
Bolognini D, Barki N, Butcher AJ, Hudson BD, Sergeev E, Molloy C, Moss CE, Bradley SJ, Le Gouill C, Bouvier M, Tobin AB, Milligan G. Chemogenetics defines receptor-mediated functions of short chain free fatty acids. Nature Chemical Biology. 15: 489-498. PMID 30992568 DOI: 10.1038/S41589-019-0270-1 |
0.463 |
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| 2019 |
Ehrlich AT, Semache M, Gross F, Da Fonte DF, Runtz L, Colley C, Mezni A, Le Gouill C, Lukasheva V, Hogue M, Darcq E, Bouvier M, Kieffer BL. Biased Signaling of the Mu Opioid Receptor Revealed in Native Neurons. Iscience. 14: 47-57. PMID 30925410 DOI: 10.1016/J.Isci.2019.03.011 |
0.797 |
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| 2019 |
Kobayashi H, Picard LP, Schönegge AM, Bouvier M. Bioluminescence resonance energy transfer-based imaging of protein-protein interactions in living cells. Nature Protocols. 14: 1084-1107. PMID 30911173 DOI: 10.1038/S41596-019-0129-7 |
0.772 |
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| 2019 |
Okeke K, Angers S, Bouvier M, Michel MC. Agonist-induced desensitisation of β -adrenoceptors: where, when and how? British Journal of Pharmacology. PMID 30809805 DOI: 10.1111/Bph.14633 |
0.644 |
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| 2019 |
Bichet D, Bouvier M, Chini B, Gimpl G, Guillon G, Kimura T, Knepper M, Lolait S, Manning M, Mouillac B, O'Carroll A, Serradeil-Le Gal C, Soloff M, Verbalis JG, Wheatley M, et al. Vasopressin and oxytocin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f66/2019.4 |
0.644 |
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| 2019 |
Imam A, Winnebeck E, Buchholz N, Froguel P, Bonnefond A, Solimena M, Ivanova A, Bouvier M, Plouffe B, Charpentier G, Karamitri A, Jockers R, Roenneberg T, Vetter C. Functional circadian and sleep phenotyping of type 2 diabetes patients with melatonin receptor 2 mutations and controls: a pilot study Sleep Medicine. 64: S166-S167. DOI: 10.1016/j.sleep.2019.11.460 |
0.694 |
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| 2018 |
Wright SC, Cañizal MCA, Benkel T, Simon K, Le Gouill C, Matricon P, Namkung Y, Lukasheva V, König GM, Laporte SA, Carlsson J, Kostenis E, Bouvier M, Schulte G, Hoffmann C. FZD is a Gα-coupled receptor that exhibits the functional hallmarks of prototypical GPCRs. Science Signaling. 11. PMID 30514810 DOI: 10.1126/Scisignal.Aar5536 |
0.824 |
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| 2018 |
Namkung Y, LeGouill C, Kumar S, Cao Y, Teixeira LB, Lukasheva V, Giubilaro J, Simões SC, Longpré JM, Devost D, Hébert TE, Piñeyro G, Leduc R, Costa-Neto CM, Bouvier M, et al. Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors. Science Signaling. 11. PMID 30514808 DOI: 10.1126/Scisignal.Aat1631 |
0.796 |
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| 2018 |
Masureel M, Zou Y, Picard LP, van der Westhuizen E, Mahoney JP, Rodrigues JPGLM, Mildorf TJ, Dror RO, Shaw DE, Bouvier M, Pardon E, Steyaert J, Sunahara RK, Weis WI, Zhang C, et al. Publisher Correction: Structural insights into binding specificity, efficacy and bias of a βAR partial agonist. Nature Chemical Biology. PMID 30504785 DOI: 10.1038/S41589-018-0182-5 |
0.77 |
|
| 2018 |
Hamoud N, Tran V, Aimi T, Kakegawa W, Lahaie S, Thibault MP, Pelletier A, Wong GW, Kim IS, Kania A, Yuzaki M, Bouvier M, Côté JF. Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion. Nature Communications. 9: 4470. PMID 30367035 DOI: 10.1038/S41467-018-06897-5 |
0.381 |
|
| 2018 |
Masureel M, Zou Y, Picard LP, van der Westhuizen E, Mahoney JP, Rodrigues JPGLM, Mildorf TJ, Dror RO, Shaw DE, Bouvier M, Pardon E, Steyaert J, Sunahara RK, Weis WI, Zhang C, et al. Structural insights into binding specificity, efficacy and bias of a βAR partial agonist. Nature Chemical Biology. 14: 1059-1066. PMID 30327561 DOI: 10.1038/S41589-018-0145-X |
0.831 |
|
| 2018 |
Mende F, Hundahl C, Plouffe B, Skov LJ, Sivertsen B, Madsen AN, Lückmann M, Diep TA, Offermanns S, Frimurer TM, Bouvier M, Holst B. Translating biased signaling in the ghrelin receptor system into differential in vivo functions. Proceedings of the National Academy of Sciences of the United States of America. PMID 30301804 DOI: 10.1073/Pnas.1804003115 |
0.813 |
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| 2018 |
Picard LP, Schönegge AM, Lohse MJ, Bouvier M. Bioluminescence resonance energy transfer-based biosensors allow monitoring of ligand- and transducer-mediated GPCR conformational changes. Communications Biology. 1: 106. PMID 30271986 DOI: 10.1038/s42003-018-0101-z |
0.843 |
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| 2018 |
Luttrell LM, Wang J, Plouffe B, Smith JS, Yamani L, Kaur S, Jean-Charles PY, Gauthier C, Lee MH, Pani B, Kim J, Ahn S, Rajagopal S, Reiter E, Bouvier M, et al. Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9. Science Signaling. 11. PMID 30254056 DOI: 10.1126/Scisignal.Aat7650 |
0.857 |
|
| 2018 |
Karamitri A, Plouffe B, Bonnefond A, Chen M, Gallion J, Guillaume JL, Hegron A, Boissel M, Canouil M, Langenberg C, Wareham NJ, Le Gouill C, Lukasheva V, Lichtarge O, Froguel P, ... Bouvier M, et al. Type 2 diabetes-associated variants of the MT melatonin receptor affect distinct modes of signaling. Science Signaling. 11. PMID 30154102 DOI: 10.1126/Scisignal.Aan6622 |
0.834 |
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| 2018 |
Young M, Dahoun T, Sokrat B, Arber C, Chen KM, Bouvier M, Barth P. Computational design of orthogonal membrane receptor-effector switches for rewiring signaling pathways. Proceedings of the National Academy of Sciences of the United States of America. PMID 29915030 DOI: 10.1073/Pnas.1718489115 |
0.851 |
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| 2018 |
Chaturvedi M, Schilling J, Beautrait A, Bouvier M, Benovic JL, Shukla AK. Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors. Trends in Biochemical Sciences. PMID 29735399 DOI: 10.1016/J.Tibs.2018.04.003 |
0.846 |
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| 2018 |
Cotnoir-White D, El Ezzy M, Boulay PL, Rozendaal M, Bouvier M, Gagnon E, Mader S. Monitoring ligand-dependent assembly of receptor ternary complexes in live cells by BRETFect. Proceedings of the National Academy of Sciences of the United States of America. PMID 29487210 DOI: 10.1073/Pnas.1716224115 |
0.473 |
|
| 2018 |
Kobayashi H, Picard L, Schönegge A, Bouvier M. Bioluminescence Resonance Energy Transfer (BRET)-based Imaging of G-Protein Coupled Receptor Signaling and Trafficking Biophysical Journal. 114: 537a. DOI: 10.1016/J.Bpj.2017.11.2936 |
0.826 |
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| 2017 |
Schönegge AM, Gallion J, Picard LP, Wilkins AD, Le Gouill C, Audet M, Stallaert W, Lohse MJ, Kimmel M, Lichtarge O, Bouvier M. Evolutionary action and structural basis of the allosteric switch controlling β2AR functional selectivity. Nature Communications. 8: 2169. PMID 29255305 DOI: 10.1038/S41467-017-02257-X |
0.837 |
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| 2017 |
Corrêa MF, Barbosa ÁJR, Teixeira LB, Duarte DA, Simões SC, Parreiras-E-Silva LT, Balbino AM, Landgraf RG, Bouvier M, Costa-Neto CM, Fernandes JPS. Pharmacological Characterization of 5-Substituted 1-[(2,3-dihydro-1-benzofuran-2-yl)methyl]piperazines: Novel Antagonists for the Histamine H3 and H4 Receptors with Anti-inflammatory Potential. Frontiers in Pharmacology. 8: 825. PMID 29184503 DOI: 10.3389/Fphar.2017.00825 |
0.404 |
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| 2017 |
Ehrlich AT, Semache M, Bailly J, Wojcik S, Arefin TM, Colley C, Le Gouill C, Gross F, Lukasheva V, Hogue M, Darcq E, Harsan LA, Bouvier M, Kieffer BL. Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing. Brain Structure & Function. PMID 29110094 DOI: 10.1007/S00429-017-1547-3 |
0.76 |
|
| 2017 |
Teixeira LB, Parreiras-E-Silva LT, Bruder-Nascimento T, Duarte DA, Simões SC, Costa RM, Rodríguez DY, Ferreira PAB, Silva CAA, Abrao EP, Oliveira EB, Bouvier M, Tostes RC, Costa-Neto CM. Ang-(1-7) is an endogenous β-arrestin-biased agonist of the AT1 receptor with protective action in cardiac hypertrophy. Scientific Reports. 7: 11903. PMID 28928410 DOI: 10.1038/S41598-017-12074-3 |
0.443 |
|
| 2017 |
Parreiras-E-Silva LT, Vargas-Pinilla P, Duarte DA, Longo D, Espinoza Pardo GV, Dulor Finkler A, Paixão-Côrtes VR, Paré P, Rovaris DL, Oliveira EB, Caceres RA, Gonçalves GL, Bouvier M, Salzano FM, Lucion AB, et al. Functional New World monkey oxytocin forms elicit an altered signaling profile and promotes parental care in rats. Proceedings of the National Academy of Sciences of the United States of America. PMID 28784762 DOI: 10.1073/Pnas.1711687114 |
0.333 |
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| 2017 |
Beautrait A, Paradis JS, Zimmerman B, Giubilaro J, Nikolajev L, Armando S, Kobayashi H, Yamani L, Namkung Y, Heydenreich FM, Khoury E, Audet M, Roux PP, Veprintsev DB, Laporte SA, ... Bouvier M, et al. A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling. Nature Communications. 8: 15054. PMID 28416805 DOI: 10.1038/Ncomms15054 |
0.83 |
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| 2017 |
Sokolina K, Kittanakom S, Snider J, Kotlyar M, Maurice P, Gandía J, Benleulmi-Chaachoua A, Tadagaki K, Oishi A, Wong V, Malty RH, Deineko V, Aoki H, Amin S, Yao Z, ... ... Bouvier M, et al. Systematic protein-protein interaction mapping for clinically relevant human GPCRs. Molecular Systems Biology. 13: 918. PMID 28298427 DOI: 10.15252/Msb.20167430 |
0.696 |
|
| 2017 |
Stallaert W, van der Westhuizen ET, Schonegge AM, Plouffe B, Hogue M, Lukashova V, Inoue A, Ishida S, Aoki J, Le Gouill C, Bouvier M. Purinergic receptor transactivation by the β2-adrenergic receptor increases intracellular Ca(2+) in non-excitable cells. Molecular Pharmacology. PMID 28280061 DOI: 10.1124/Mol.116.106419 |
0.833 |
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| 2017 |
Möller D, Banerjee A, Uzuneser TC, Skultety M, Huth T, Plouffe B, Hübner H, Alzheimer C, Friedland K, Müller CP, Bouvier M, Gmeiner P. Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5-a]pyridine Substructure. Journal of Medicinal Chemistry. PMID 28248104 DOI: 10.1021/Acs.Jmedchem.6B01857 |
0.802 |
|
| 2017 |
Gallion J, Koire A, Katsonis P, Schoenegge AM, Bouvier M, Lichtarge O. Predicting phenotype from genotype: Improving accuracy through more robust experimental and computational modeling. Human Mutation. PMID 28230923 DOI: 10.1002/Humu.23193 |
0.764 |
|
| 2017 |
Cahill TJ, Thomsen AR, Tarrasch JT, Plouffe B, Nguyen AH, Yang F, Huang LY, Kahsai AW, Bassoni DL, Gavino BJ, Lamerdin JE, Triest S, Shukla AK, Berger B, Little J, ... ... Bouvier M, et al. Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223524 DOI: 10.1073/Pnas.1701529114 |
0.851 |
|
| 2017 |
Ramachandran R, Mihara K, Thibeault P, Vanderboor CM, Petri B, Saifeddine M, Bouvier M, Hollenberg MD. Targeting a PAR4 carboxyl terminal motif to regulate platelet function. Molecular Pharmacology. PMID 28126849 DOI: 10.1124/Mol.116.106526 |
0.375 |
|
| 2017 |
Wong PC, Seiffert D, Bird JE, Watson CA, Bostwick JS, Giancarli M, Allegretto N, Hua J, Harden D, Guay J, Callejo M, Miller MM, Lawrence RM, Banville J, Guy J, ... ... Bouvier M, et al. Blockade of protease-activated receptor-4 (PAR4) provides robust antithrombotic activity with low bleeding. Science Translational Medicine. 9. PMID 28053157 DOI: 10.1126/Scitranslmed.Aaf5294 |
0.369 |
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| 2017 |
Cahill T, Thomsen A, Plouffe B, Bouvier M, Lefkowitz R. LB987 New insights into gpcr-transducer coupling Journal of Investigative Dermatology. 137: B10. DOI: 10.1016/J.Jid.2017.07.067 |
0.79 |
|
| 2016 |
Fritzius T, Turecek R, Seddik R, Kobayashi H, Tiao J, Rem PD, Metz M, Kralikova M, Bouvier M, Gassmann M, Bettler B. KCTD hetero-oligomers confer unique kinetic properties on hippocampal GABAB receptor-induced K+-currents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28003345 DOI: 10.1523/Jneurosci.2181-16.2016 |
0.507 |
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| 2016 |
Costa-Neto CM, Parreiras-E-Silva LT, Bouvier M. A pluridimensional view of biased agonism. Molecular Pharmacology. PMID 27638872 DOI: 10.1124/Mol.116.105940 |
0.439 |
|
| 2016 |
Venkatakrishnan AJ, Deupi X, Lebon G, Heydenreich FM, Flock T, Miljus T, Balaji S, Bouvier M, Veprintsev DB, Tate CG, Schertler GF, Babu MM. Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region. Nature. PMID 27525504 DOI: 10.1038/Nature19107 |
0.835 |
|
| 2016 |
Thomsen AR, Plouffe B, Cahill TJ, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, ... Bouvier M, et al. GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling. Cell. PMID 27499021 DOI: 10.1016/J.Cell.2016.07.004 |
0.848 |
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| 2016 |
Namkung Y, Le Gouill C, Lukashova V, Kobayashi H, Hogue M, Khoury E, Song M, Bouvier M, Laporte SA. Monitoring G protein-coupled receptor and β-arrestin trafficking in live cells using enhanced bystander BRET. Nature Communications. 7: 12178. PMID 27397672 DOI: 10.1038/Ncomms12178 |
0.519 |
|
| 2016 |
Bradley SJ, Wiegman CH, Iglesias MM, Kong KC, Butcher AJ, Plouffe B, Goupil E, Bourgognon JM, Macedo-Hatch T, LeGouill C, Russell K, Laporte SA, König GM, Kostenis E, Bouvier M, et al. Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction. Proceedings of the National Academy of Sciences of the United States of America. PMID 27071102 DOI: 10.1073/Pnas.1521706113 |
0.791 |
|
| 2016 |
Devost D, Audet N, Zhou C, Kobayashi H, Bonin H, Lukashova V, Le Gouill C, Bouvier M, Hébert TE. Cellular and subcellular context determine outputs from signaling biosensors. Methods in Cell Biology. 132: 319-37. PMID 26928550 DOI: 10.1016/Bs.Mcb.2015.11.010 |
0.415 |
|
| 2016 |
Lahaie N, Kralikova M, Pr Eacutezeau L, Blahos J, Bouvier M. Post-endocytotic deubiquitination and degradation of the metabotropic γ-aminobutyric acid receptor by the ubiquitin specific protease 14. The Journal of Biological Chemistry. PMID 26817839 DOI: 10.1074/Jbc.M115.686907 |
0.858 |
|
| 2015 |
Schrage R, Schmitz AL, Gaffal E, Annala S, Kehraus S, Wenzel D, Büllesbach KM, Bald T, Inoue A, Shinjo Y, Galandrin S, Shridhar N, Hesse M, Grundmann M, Merten N, ... ... Bouvier M, et al. The experimental power of FR900359 to study Gq-regulated biological processes. Nature Communications. 6: 10156. PMID 26658454 DOI: 10.1038/Ncomms10156 |
0.819 |
|
| 2015 |
Paradis JS, Ly S, Blondel-Tepaz É, Galan JA, Beautrait A, Scott MG, Enslen H, Marullo S, Roux PP, Bouvier M. Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression. Proceedings of the National Academy of Sciences of the United States of America. 112: E5160-8. PMID 26324936 DOI: 10.1073/Pnas.1508836112 |
0.857 |
|
| 2015 |
Santos GA, Duarte DA, Parreiras-E-Silva LT, Teixeira FR, Silva-Rocha R, Oliveira EB, Bouvier M, Costa-Neto CM. Comparative analyses of downstream signal transduction targets modulated after activation of the AT1 receptor by two β-arrestin-biased agonists. Frontiers in Pharmacology. 6: 131. PMID 26191004 DOI: 10.3389/Fphar.2015.00131 |
0.547 |
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| 2015 |
Mancini AD, Bertrand G, Vivot K, Carpentier É, Tremblay C, Ghislain J, Bouvier M, Poitout V. β-Arrestin Recruitment and Biased Agonism at Free Fatty Acid Receptor 1. The Journal of Biological Chemistry. 290: 21131-40. PMID 26157145 DOI: 10.1074/Jbc.M115.644450 |
0.698 |
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| 2015 |
van Unen J, Woolard J, Rinken A, Hoffmann C, Hill SJ, Goedhart J, Bruchas MR, Bouvier M, Adjobo-Hermans MJ. A Perspective on Studying G-Protein-Coupled Receptor Signaling with Resonance Energy Transfer Biosensors in Living Organisms. Molecular Pharmacology. 88: 589-95. PMID 25972446 DOI: 10.1124/Mol.115.098897 |
0.481 |
|
| 2015 |
Maiga A, Lemieux S, Pabst C, Lavallée V, Bouvier M, Sauvageau G, Hébert J. Transcriptome Analysis Reveals That G Protein-Coupled Receptors Are Potential Diagnostic Markers or Therapeutic Targets in Acute Myeloid Leukemia Blood. 126: 3855-3855. DOI: 10.1182/Blood.V126.23.3855.3855 |
0.795 |
|
| 2014 |
Carr R, Du Y, Quoyer J, Panettieri RA, Janz JM, Bouvier M, Kobilka BK, Benovic JL. Development and characterization of pepducins as Gs-biased allosteric agonists. The Journal of Biological Chemistry. 289: 35668-84. PMID 25395624 DOI: 10.1074/Jbc.M114.618819 |
0.86 |
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| 2014 |
Armando S, Quoyer J, Lukashova V, Maiga A, Percherancier Y, Heveker N, Pin JP, Prézeau L, Bouvier M. The chemokine CXC4 and CC2 receptors form homo- and heterooligomers that can engage their signaling G-protein effectors and βarrestin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4509-23. PMID 25053617 DOI: 10.1096/Fj.13-242446 |
0.846 |
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| 2014 |
Beautrait A, Michalski KR, Lopez TS, Mannix KM, McDonald DJ, Cutter AR, Medina CB, Hebert AM, Francis CJ, Bouvier M, Tesmer JJ, Sterne-Marr R. Mapping the putative G protein-coupled receptor (GPCR) docking site on GPCR kinase 2: insights from intact cell phosphorylation and recruitment assays. The Journal of Biological Chemistry. 289: 25262-75. PMID 25049229 DOI: 10.1074/Jbc.M114.593178 |
0.847 |
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| 2014 |
Lima-Fernandes E, Misticone S, Boularan C, Paradis JS, Enslen H, Roux PP, Bouvier M, Baillie GS, Marullo S, Scott MG. A biosensor to monitor dynamic regulation and function of tumour suppressor PTEN in living cells. Nature Communications. 5: 4431. PMID 25028204 DOI: 10.1038/Ncomms5431 |
0.819 |
|
| 2014 |
Ceraudo E, Galanth C, Carpentier E, Banegas-Font I, Schonegge AM, Alvear-Perez R, Iturrioz X, Bouvier M, Llorens-Cortes C. Biased signaling favoring gi over β-arrestin promoted by an apelin fragment lacking the C-terminal phenylalanine. The Journal of Biological Chemistry. 289: 24599-610. PMID 25012663 DOI: 10.1074/Jbc.M113.541698 |
0.699 |
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| 2014 |
Lackman JJ, Markkanen PM, Hogue M, Bouvier M, Petäjä-Repo UE. N-Glycan-dependent and -independent quality control of human δ opioid receptor N-terminal variants. The Journal of Biological Chemistry. 289: 17830-42. PMID 24798333 DOI: 10.1074/Jbc.M114.566273 |
0.747 |
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| 2014 |
Thanawala VJ, Forkuo GS, Stallaert W, Leff P, Bouvier M, Bond R. Ligand bias prevents class equality among beta-blockers. Current Opinion in Pharmacology. 16: 50-7. PMID 24681351 DOI: 10.1016/J.Coph.2014.03.002 |
0.772 |
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| 2014 |
Sauvageau E, Rochdi MD, Oueslati M, Hamdan FF, Percherancier Y, Simpson JC, Pepperkok R, Bouvier M. CNIH4 interacts with newly synthesized GPCR and controls their export from the endoplasmic reticulum. Traffic (Copenhagen, Denmark). 15: 383-400. PMID 24405750 DOI: 10.1111/Tra.12148 |
0.85 |
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| 2014 |
van der Westhuizen ET, Breton B, Christopoulos A, Bouvier M. Quantification of ligand bias for clinically relevant β2-adrenergic receptor ligands: implications for drug taxonomy. Molecular Pharmacology. 85: 492-509. PMID 24366668 DOI: 10.1124/Mol.113.088880 |
0.84 |
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| 2014 |
Mancini A, Bertrand G, Vivot K, Carpentier E, Ghislain J, Bouvier M, Poitout V. Beta-Arrestin 2 Recruitment and Biased Agonism at the Free Fatty Acid Receptor GPR40 Canadian Journal of Diabetes. 38: S66. DOI: 10.1016/J.Jcjd.2014.07.187 |
0.613 |
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| 2014 |
Schann S, Neuville P, Bouvier M. Novel Screening Paradigms for the Identification of Allosteric Modulators and/or Biased Ligands for Challenging G-Protein-Coupled Receptors Annual Reports in Medicinal Chemistry. 49: 285-300. DOI: 10.1016/B978-0-12-800167-7.00018-3 |
0.404 |
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| 2013 |
Quoyer J, Janz JM, Luo J, Ren Y, Armando S, Lukashova V, Benovic JL, Carlson KE, Hunt SW, Bouvier M. Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein. Proceedings of the National Academy of Sciences of the United States of America. 110: E5088-97. PMID 24309376 DOI: 10.1073/Pnas.1312515110 |
0.862 |
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| 2013 |
Schann S, Bouvier M, Neuville P. Technology combination to address GPCR allosteric modulator drug-discovery pitfalls. Drug Discovery Today. Technologies. 10: e261-7. PMID 24050277 DOI: 10.1016/J.Ddtec.2012.09.008 |
0.395 |
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| 2013 |
Bouvier M. Unraveling the structural basis of GPCR activation and inactivation. Nature Structural & Molecular Biology. 20: 539-41. PMID 23649361 DOI: 10.1038/Nsmb.2584 |
0.547 |
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| 2013 |
Samuels ME, Gallo-Payet N, Pinard S, Hasselmann C, Magne F, Patry L, Chouinard L, Schwartzentruber J, René P, Sawyer N, Bouvier M, Djemli A, Delvin E, Huot C, Eugene D, et al. Bioinactive ACTH causing glucocorticoid deficiency. The Journal of Clinical Endocrinology and Metabolism. 98: 736-42. PMID 23293326 DOI: 10.1210/Jc.2012-3199 |
0.341 |
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| 2013 |
Richard-Lalonde M, Nagi K, Audet N, Sleno R, Amraei M, Hogue M, Balboni G, Schiller PW, Bouvier M, Hébert TE, Pineyro G. Conformational dynamics of Kir3.1/Kir3.2 channel activation via δ-opioid receptors. Molecular Pharmacology. 83: 416-28. PMID 23175530 DOI: 10.1124/Mol.112.081950 |
0.728 |
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| 2013 |
Mancini AD, Carpentier É, Bouvier M, Poitout V. TAK-875 is a Partial Agonist of the Free Fatty Acid Receptor GPR40 Canadian Journal of Diabetes. 37: S59. DOI: 10.1016/J.Jcjd.2013.08.176 |
0.657 |
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| 2013 |
Bouvier M. Probing G Protein-Coupled Receptor Signalling Complex Dynamics and Cellular Outcomes in Living Cells using Bioluminescence Resonance Energy Transfer (BRET) Biophysical Journal. 104: 44a-45a. DOI: 10.1016/J.Bpj.2012.11.284 |
0.485 |
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| 2013 |
van der Westhuizen E, Stallaert W, Murat B, Audet M, Galandrin S, Lagacé M, Bouvier M. Probing the Functional Selectivity of β-adrenergic Receptors Reveals New Signaling Modes and Potential Therapeutic Applications Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 112. DOI: 10.1016/B978-0-12-800044-1.00098-2 |
0.821 |
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| 2012 |
Audet M, Bouvier M. Restructuring G-protein- coupled receptor activation. Cell. 151: 14-23. PMID 23021212 DOI: 10.1016/J.Cell.2012.09.003 |
0.739 |
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| 2012 |
Carpentier E, Greenbaum LA, Rochdi D, Abrol R, Goddard WA, Bichet DG, Bouvier M. Identification and characterization of an activating F229V substitution in the V2 vasopressin receptor in an infant with NSIAD. Journal of the American Society of Nephrology : Jasn. 23: 1635-40. PMID 22956819 DOI: 10.1681/Asn.2012010077 |
0.836 |
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| 2012 |
Hilmi K, Hussein N, Mendoza-Sanchez R, El-Ezzy M, Ismail H, Durette C, Bail M, Rozendaal MJ, Bouvier M, Thibault P, Gleason JL, Mader S. Role of SUMOylation in full antiestrogenicity. Molecular and Cellular Biology. 32: 3823-37. PMID 22826433 DOI: 10.1128/Mcb.00290-12 |
0.486 |
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| 2012 |
Zimmerman B, Beautrait A, Aguila B, Charles R, Escher E, Claing A, Bouvier M, Laporte SA. Differential β-arrestin-dependent conformational signaling and cellular responses revealed by angiotensin analogs. Science Signaling. 5: ra33. PMID 22534132 DOI: 10.1126/Scisignal.2002522 |
0.855 |
|
| 2012 |
Oligny-Longpré G, Corbani M, Zhou J, Hogue M, Guillon G, Bouvier M. Engagement of β-arrestin by transactivated insulin-like growth factor receptor is needed for V2 vasopressin receptor-stimulated ERK1/2 activation. Proceedings of the National Academy of Sciences of the United States of America. 109: E1028-37. PMID 22493236 DOI: 10.1073/Pnas.1112422109 |
0.851 |
|
| 2012 |
Stallaert W, Dorn JF, van der Westhuizen E, Audet M, Bouvier M. Impedance responses reveal β₂-adrenergic receptor signaling pluridimensionality and allow classification of ligands with distinct signaling profiles. Plos One. 7: e29420. PMID 22242170 DOI: 10.1371/Journal.Pone.0029420 |
0.85 |
|
| 2012 |
Leskelä TT, Lackman JJ, Vierimaa MM, Kobayashi H, Bouvier M, Petäjä-Repo UE. Cys-27 variant of human δ-opioid receptor modulates maturation and cell surface delivery of Phe-27 variant via heteromerization. The Journal of Biological Chemistry. 287: 5008-20. PMID 22184124 DOI: 10.1074/Jbc.M111.305656 |
0.77 |
|
| 2012 |
Busnelli M, Saulière A, Manning M, Bouvier M, Galés C, Chini B. Functional selective oxytocin-derived agonists discriminate between individual G protein family subtypes. The Journal of Biological Chemistry. 287: 3617-29. PMID 22069312 DOI: 10.1074/Jbc.M111.277178 |
0.448 |
|
| 2011 |
Stallaert W, Christopoulos A, Bouvier M. Ligand functional selectivity and quantitative pharmacology at G protein-coupled receptors. Expert Opinion On Drug Discovery. 6: 811-25. PMID 22651124 DOI: 10.1517/17460441.2011.586691 |
0.825 |
|
| 2011 |
Stefan E, Malleshaiah MK, Breton B, Ear PH, Bachmann V, Beyermann M, Bouvier M, Michnick SW. PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades. Nature Communications. 2: 598. PMID 22186894 DOI: 10.1038/Ncomms1605 |
0.814 |
|
| 2011 |
Yagi H, Tan W, Dillenburg-Pilla P, Armando S, Amornphimoltham P, Simaan M, Weigert R, Molinolo AA, Bouvier M, Gutkind JS. A synthetic biology approach reveals a CXCR4-G13-Rho signaling axis driving transendothelial migration of metastatic breast cancer cells. Science Signaling. 4: ra60. PMID 21934106 DOI: 10.1126/Scisignal.2002221 |
0.832 |
|
| 2011 |
Dimond P, Carlson K, Bouvier M, Gerard C, Xu L, Covic L, Agarwal A, Ernst OP, Janz JM, Schwartz TW, Gardella TJ, Milligan G, Kuliopulos A, Sakmar TP, Hunt SW. G protein-coupled receptor modulation with pepducins: moving closer to the clinic. Annals of the New York Academy of Sciences. 1226: 34-49. PMID 21615752 DOI: 10.1111/J.1749-6632.2011.06039.X |
0.529 |
|
| 2011 |
Ramachandran R, Mihara K, Chung H, Renaux B, Lau CS, Muruve DA, DeFea KA, Bouvier M, Hollenberg MD. Neutrophil elastase acts as a biased agonist for proteinase-activated receptor-2 (PAR2). The Journal of Biological Chemistry. 286: 24638-48. PMID 21576245 DOI: 10.1074/Jbc.M110.201988 |
0.485 |
|
| 2011 |
Fulton S, Thibault D, Mendez JA, Lahaie N, Tirotta E, Borrelli E, Bouvier M, Tempel BL, Trudeau LE. Contribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflow. The Journal of Biological Chemistry. 286: 9360-72. PMID 21233214 DOI: 10.1074/Jbc.M110.153262 |
0.774 |
|
| 2010 |
Breton B, Sauvageau É, Zhou J, Bonin H, Le Gouill C, Bouvier M. Multiplexing of multicolor bioluminescence resonance energy transfer. Biophysical Journal. 99: 4037-46. PMID 21156147 DOI: 10.1016/J.Bpj.2010.10.025 |
0.821 |
|
| 2010 |
Patel M, Margaron Y, Fradet N, Yang Q, Wilkes B, Bouvier M, Hofmann K, Côté JF. An evolutionarily conserved autoinhibitory molecular switch in ELMO proteins regulates Rac signaling. Current Biology : Cb. 20: 2021-7. PMID 21035343 DOI: 10.1016/J.Cub.2010.10.028 |
0.401 |
|
| 2010 |
René P, Le Gouill C, Pogozheva ID, Lee G, Mosberg HI, Farooqi IS, Valenzano KJ, Bouvier M. Pharmacological chaperones restore function to MC4R mutants responsible for severe early-onset obesity. The Journal of Pharmacology and Experimental Therapeutics. 335: 520-32. PMID 20826565 DOI: 10.1124/Jpet.110.172098 |
0.412 |
|
| 2010 |
Oner SS, An N, Vural A, Breton B, Bouvier M, Blumer JB, Lanier SM. Regulation of the AGS3·G{alpha}i signaling complex by a seven-transmembrane span receptor. The Journal of Biological Chemistry. 285: 33949-58. PMID 20716524 DOI: 10.1074/Jbc.M110.138073 |
0.809 |
|
| 2010 |
Breton B, Lagacé M, Bouvier M. Combining resonance energy transfer methods reveals a complex between the alpha2A-adrenergic receptor, Galphai1beta1gamma2, and GRK2. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 4733-43. PMID 20696855 DOI: 10.1096/fj.10.164061 |
0.813 |
|
| 2010 |
Goupil E, Tassy D, Bourguet C, Quiniou C, Wisehart V, Pétrin D, Le Gouill C, Devost D, Zingg HH, Bouvier M, Saragovi HU, Chemtob S, Lubell WD, Claing A, Hébert TE, et al. A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2alpha-mediated Rho/ROCK signaling pathway. The Journal of Biological Chemistry. 285: 25624-36. PMID 20551320 DOI: 10.1074/Jbc.M110.115196 |
0.755 |
|
| 2010 |
Khelashvili G, Dorff K, Shan J, Camacho-Artacho M, Skrabanek L, Vroling B, Bouvier M, Devi LA, George SR, Javitch JA, Lohse MJ, Milligan G, Neubig RR, Palczewski K, Parmentier M, et al. GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base. Bioinformatics (Oxford, England). 26: 1804-5. PMID 20501551 DOI: 10.1093/Bioinformatics/Btq264 |
0.625 |
|
| 2010 |
Oner SS, Maher EM, Breton B, Bouvier M, Blumer JB. Receptor-regulated interaction of activator of G-protein signaling-4 and Galphai. The Journal of Biological Chemistry. 285: 20588-94. PMID 20452976 DOI: 10.1074/Jbc.C109.088070 |
0.817 |
|
| 2010 |
Solinski HJ, Boekhoff I, Bouvier M, Gudermann T, Breit A. Sensory neuron-specific MAS-related gene-X1 receptors resist agonist-promoted endocytosis. Molecular Pharmacology. 78: 249-59. PMID 20424127 DOI: 10.1124/Mol.110.063867 |
0.783 |
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| 2010 |
Audet M, Lagacé M, Silversides DW, Bouvier M. Protein-protein interactions monitored in cells from transgenic mice using bioluminescence resonance energy transfer. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2829-38. PMID 20335229 DOI: 10.1096/Fj.09-144816 |
0.677 |
|
| 2010 |
Rochdi MD, Vargas GA, Carpentier E, Oligny-Longpré G, Chen S, Kovoor A, Gitelman SE, Rosenthal SM, von Zastrow M, Bouvier M. Functional characterization of vasopressin type 2 receptor substitutions (R137H/C/L) leading to nephrogenic diabetes insipidus and nephrogenic syndrome of inappropriate antidiuresis: implications for treatments. Molecular Pharmacology. 77: 836-45. PMID 20159941 DOI: 10.1124/Mol.109.061804 |
0.658 |
|
| 2010 |
Martel C, Dugré-Brisson S, Boulay K, Breton B, Lapointe G, Armando S, Trépanier V, Duchaîne T, Bouvier M, Desgroseillers L. Multimerization of Staufen1 in live cells. Rna (New York, N.Y.). 16: 585-97. PMID 20075165 DOI: 10.1261/Rna.1664210 |
0.79 |
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| 2010 |
Busillo JM, Armando S, Sengupta R, Meucci O, Bouvier M, Benovic JL. Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling. The Journal of Biological Chemistry. 285: 7805-17. PMID 20048153 DOI: 10.1074/Jbc.M109.091173 |
0.826 |
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| 2010 |
Bockenhauer D, Carpentier E, Rochdi D, van't Hoff W, Breton B, Bernier V, Bouvier M, Bichet DG. Vasopressin type 2 receptor V88M mutation: molecular basis of partial and complete nephrogenic diabetes insipidus. Nephron. Physiology. 114: p1-10. PMID 19816050 DOI: 10.1159/000245059 |
0.807 |
|
| 2010 |
Valenzano KJ, Benjamin ER, René P, Bouvier M. Pharmacological Chaperones: Potential for the Treatment of Hereditary Diseases Caused by Mutations in G Protein-Coupled Receptors Gpcr Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions. 460-510. DOI: 10.1002/9780470627327.ch17 |
0.336 |
|
| 2009 |
Rihakova L, Quiniou C, Hamdan FF, Kaul R, Brault S, Hou X, Lahaie I, Sapieha P, Hamel D, Shao Z, Gobeil F, Hardy P, Joyal JS, Nedev H, Duhamel F, ... ... Bouvier M, et al. VRQ397 (CRAVKY): a novel noncompetitive V2 receptor antagonist. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 297: R1009-18. PMID 19641130 DOI: 10.1152/ajpregu.90766.2008 |
0.675 |
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| 2009 |
Ramachandran R, Mihara K, Mathur M, Rochdi MD, Bouvier M, Defea K, Hollenberg MD. Agonist-biased signaling via proteinase activated receptor-2: differential activation of calcium and mitogen-activated protein kinase pathways. Molecular Pharmacology. 76: 791-801. PMID 19605524 DOI: 10.1124/Mol.109.055509 |
0.466 |
|
| 2009 |
Leduc M, Breton B, Galés C, Le Gouill C, Bouvier M, Chemtob S, Heveker N. Functional selectivity of natural and synthetic prostaglandin EP4 receptor ligands. The Journal of Pharmacology and Experimental Therapeutics. 331: 297-307. PMID 19584306 DOI: 10.1124/Jpet.109.156398 |
0.802 |
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| 2009 |
Kobayashi H, Ogawa K, Yao R, Lichtarge O, Bouvier M. Functional rescue of beta-adrenoceptor dimerization and trafficking by pharmacological chaperones. Traffic (Copenhagen, Denmark). 10: 1019-33. PMID 19515093 DOI: 10.1111/J.1600-0854.2009.00932.X |
0.418 |
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| 2009 |
Ferré S, Baler R, Bouvier M, Caron MG, Devi LA, Durroux T, Fuxe K, George SR, Javitch JA, Lohse MJ, Mackie K, Milligan G, Pfleger KD, Pin JP, Volkow ND, et al. Building a new conceptual framework for receptor heteromers. Nature Chemical Biology. 5: 131-4. PMID 19219011 DOI: 10.1038/Nchembio0309-131 |
0.67 |
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| 2008 |
Matsubayashi J, Takanashi M, Oikawa K, Fujita K, Tanaka M, Xu M, De Blasi A, Bouvier M, Kinoshita M, Kuroda M, Mukai K. Expression of G protein-coupled receptor kinase 4 is associated with breast cancer tumourigenesis. The Journal of Pathology. 216: 317-27. PMID 18767025 DOI: 10.1002/Path.2414 |
0.445 |
|
| 2008 |
Pontier SM, Percherancier Y, Galandrin S, Breit A, Galés C, Bouvier M. Cholesterol-dependent separation of the beta2-adrenergic receptor from its partners determines signaling efficacy: insight into nanoscale organization of signal transduction. The Journal of Biological Chemistry. 283: 24659-72. PMID 18566454 DOI: 10.1074/Jbc.M800778200 |
0.836 |
|
| 2008 |
Audet M, Bouvier M. Insights into signaling from the beta2-adrenergic receptor structure. Nature Chemical Biology. 4: 397-403. PMID 18560432 DOI: 10.1038/Nchembio.97 |
0.721 |
|
| 2008 |
Galandrin S, Oligny-Longpré G, Bonin H, Ogawa K, Galés C, Bouvier M. Conformational rearrangements and signaling cascades involved in ligand-biased mitogen-activated protein kinase signaling through the beta1-adrenergic receptor. Molecular Pharmacology. 74: 162-72. PMID 18403719 DOI: 10.1124/mol.107.043893 |
0.851 |
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| 2008 |
Audet N, Galés C, Archer-Lahlou E, Vallières M, Schiller PW, Bouvier M, Pineyro G. Bioluminescence resonance energy transfer assays reveal ligand-specific conformational changes within preformed signaling complexes containing delta-opioid receptors and heterotrimeric G proteins. The Journal of Biological Chemistry. 283: 15078-88. PMID 18381293 DOI: 10.1074/Jbc.M707941200 |
0.797 |
|
| 2008 |
Ouedraogo M, Lecat S, Rochdi MD, Hachet-Haas M, Matthes H, Gicquiaux H, Verrier S, Gaire M, Glasser N, Mély Y, Takeda K, Bouvier M, Galzi JL, Bucher B. Distinct motifs of neuropeptide Y receptors differentially regulate trafficking and desensitization. Traffic (Copenhagen, Denmark). 9: 305-24. PMID 18088318 DOI: 10.1111/J.1600-0854.2007.00691.X |
0.493 |
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| 2008 |
Coulon V, Audet M, Homburger V, Bockaert J, Fagni L, Bouvier M, Perroy J. Subcellular imaging of dynamic protein interactions by bioluminescence resonance energy transfer. Biophysical Journal. 94: 1001-9. PMID 17921204 DOI: 10.1529/Biophysj.107.117275 |
0.792 |
|
| 2007 |
Galés C, Bouvier M. [New talk between receptor and trimeric G proteins: "an intertwined body dance"]. Mã©Decine Sciences : M/S. 23: 1031-4. PMID 18021724 DOI: 10.1051/Medsci/200723111031 |
0.48 |
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| 2007 |
Stefan E, Aquin S, Berger N, Landry CR, Nyfeler B, Bouvier M, Michnick SW. Quantification of dynamic protein complexes using Renilla luciferase fragment complementation applied to protein kinase A activities in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 16916-21. PMID 17942691 DOI: 10.1073/Pnas.0704257104 |
0.546 |
|
| 2007 |
Héroux M, Hogue M, Lemieux S, Bouvier M. Functional calcitonin gene-related peptide receptors are formed by the asymmetric assembly of a calcitonin receptor-like receptor homo-oligomer and a monomer of receptor activity-modifying protein-1. The Journal of Biological Chemistry. 282: 31610-20. PMID 17785463 DOI: 10.1074/Jbc.M701790200 |
0.563 |
|
| 2007 |
Hamdan FF, Rochdi MD, Breton B, Fessart D, Michaud DE, Charest PG, Laporte SA, Bouvier M. Unraveling G protein-coupled receptor endocytosis pathways using real-time monitoring of agonist-promoted interaction between beta-arrestins and AP-2. The Journal of Biological Chemistry. 282: 29089-100. PMID 17675294 DOI: 10.1074/Jbc.M700577200 |
0.829 |
|
| 2007 |
Galandrin S, Oligny-Longpré G, Bouvier M. The evasive nature of drug efficacy: implications for drug discovery. Trends in Pharmacological Sciences. 28: 423-30. PMID 17659355 DOI: 10.1016/J.Tips.2007.06.005 |
0.829 |
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| 2007 |
Skrabanek L, Murcia M, Bouvier M, Devi L, George SR, Lohse MJ, Milligan G, Neubig R, Palczewski K, Parmentier M, Pin JP, Vriend G, Javitch JA, Campagne F, Filizola M. Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base. Bmc Bioinformatics. 8: 177. PMID 17537266 DOI: 10.1186/1471-2105-8-177 |
0.587 |
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| 2007 |
Héroux M, Breton B, Hogue M, Bouvier M. Assembly and signaling of CRLR and RAMP1 complexes assessed by BRET. Biochemistry. 46: 7022-33. PMID 17503773 DOI: 10.1021/Bi0622470 |
0.82 |
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| 2007 |
Fessart D, Simaan M, Zimmerman B, Comeau J, Hamdan FF, Wiseman PW, Bouvier M, Laporte SA. Src-dependent phosphorylation of beta2-adaptin dissociates the beta-arrestin-AP-2 complex. Journal of Cell Science. 120: 1723-32. PMID 17456551 DOI: 10.1242/Jcs.03444 |
0.673 |
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| 2007 |
Pin JP, Neubig R, Bouvier M, Devi L, Filizola M, Javitch JA, Lohse MJ, Milligan G, Palczewski K, Parmentier M, Spedding M. International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers. Pharmacological Reviews. 59: 5-13. PMID 17329545 DOI: 10.1124/Pr.59.1.5 |
0.657 |
|
| 2007 |
Boeglin D, Hamdan FF, Melendez RE, Cluzeau J, Laperriere A, Héroux M, Bouvier M, Lubell WD. Calcitonin gene-related peptide analogues with aza and indolizidinone amino acid residues reveal conformational requirements for antagonist activity at the human calcitonin gene-related peptide 1 receptor. Journal of Medicinal Chemistry. 50: 1401-8. PMID 17319653 DOI: 10.1021/Jm061343W |
0.586 |
|
| 2007 |
Bouvier M, Heveker N, Jockers R, Marullo S, Milligan G. BRET analysis of GPCR oligomerization: newer does not mean better. Nature Methods. 4: 3-4; author reply 4. PMID 17195017 DOI: 10.1038/Nmeth0107-3 |
0.398 |
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| 2007 |
Charest PG, Oligny-Longpré G, Bonin H, Azzi M, Bouvier M. The V2 vasopressin receptor stimulates ERK1/2 activity independently of heterotrimeric G protein signalling. Cellular Signalling. 19: 32-41. PMID 16857342 DOI: 10.1016/J.Cellsig.2006.05.020 |
0.837 |
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| 2006 |
Hamdan FF, Percherancier Y, Breton B, Bouvier M. Monitoring protein-protein interactions in living cells by bioluminescence resonance energy transfer (BRET). Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 5.23. PMID 18428639 DOI: 10.1002/0471142301.Ns0523S34 |
0.822 |
|
| 2006 |
Galés C, Van Durm JJ, Schaak S, Pontier S, Percherancier Y, Audet M, Paris H, Bouvier M. Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes. Nature Structural & Molecular Biology. 13: 778-86. PMID 16906158 DOI: 10.1038/Nsmb1134 |
0.837 |
|
| 2006 |
Galandrin S, Bouvier M. Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy. Molecular Pharmacology. 70: 1575-84. PMID 16901982 DOI: 10.1124/Mol.106.026716 |
0.845 |
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| 2006 |
Rebois RV, Robitaille M, Galés C, Dupré DJ, Baragli A, Trieu P, Ethier N, Bouvier M, Hébert TE. Heterotrimeric G proteins form stable complexes with adenylyl cyclase and Kir3.1 channels in living cells. Journal of Cell Science. 119: 2807-18. PMID 16787947 DOI: 10.1242/Jcs.03021 |
0.508 |
|
| 2006 |
Pontier SM, Lahaie N, Ginham R, St-Gelais F, Bonin H, Bell DJ, Flynn H, Trudeau LE, McIlhinney J, White JH, Bouvier M. Coordinated action of NSF and PKC regulates GABAB receptor signaling efficacy. The Embo Journal. 25: 2698-709. PMID 16724110 DOI: 10.1038/Sj.Emboj.7601157 |
0.85 |
|
| 2006 |
Breit A, Gagnidze K, Devi LA, Lagacé M, Bouvier M. Simultaneous activation of the delta opioid receptor (deltaOR)/sensory neuron-specific receptor-4 (SNSR-4) hetero-oligomer by the mixed bivalent agonist bovine adrenal medulla peptide 22 activates SNSR-4 but inhibits deltaOR signaling. Molecular Pharmacology. 70: 686-96. PMID 16682504 DOI: 10.1124/Mol.106.022897 |
0.782 |
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| 2006 |
Petäjä-Repo UE, Hogue M, Leskelä TT, Markkanen PM, Tuusa JT, Bouvier M. Distinct subcellular localization for constitutive and agonist-modulated palmitoylation of the human delta opioid receptor. The Journal of Biological Chemistry. 281: 15780-9. PMID 16595649 DOI: 10.1074/Jbc.M602267200 |
0.81 |
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| 2006 |
Barbas D, Zappulla JP, Angers S, Bouvier M, Mohamed HA, Byrne JH, Castellucci VF, DesGroseillers L. An aplysia dopamine1-like receptor: molecular and functional characterization. Journal of Neurochemistry. 96: 414-27. PMID 16336222 DOI: 10.1111/J.1471-4159.2005.03561.X |
0.677 |
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| 2006 |
Bernier V, Morello JP, Zarruk A, Debrand N, Salahpour A, Lonergan M, Arthus MF, Laperrière A, Brouard R, Bouvier M, Bichet DG. Pharmacologic chaperones as a potential treatment for X-linked nephrogenic diabetes insipidus. Journal of the American Society of Nephrology : Jasn. 17: 232-43. PMID 16319185 DOI: 10.1681/Asn.2005080854 |
0.829 |
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| 2006 |
Reversi A, Galés C, Bouvier M, Chini B. G-protein coupling specificity of the human oxytocin receptor Frontiers in Neuroendocrinology. 27: 123. DOI: 10.1016/J.Yfrne.2006.03.321 |
0.761 |
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| 2005 |
Storez H, Scott MG, Issafras H, Burtey A, Benmerah A, Muntaner O, Piolot T, Tramier M, Coppey-Moisan M, Bouvier M, Labbé-Jullié C, Marullo S. Homo- and hetero-oligomerization of beta-arrestins in living cells. The Journal of Biological Chemistry. 280: 40210-5. PMID 16199535 DOI: 10.1074/Jbc.M508001200 |
0.388 |
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| 2005 |
Hamdan FF, Audet M, Garneau P, Pelletier J, Bouvier M. High-throughput screening of G protein-coupled receptor antagonists using a bioluminescence resonance energy transfer 1-based beta-arrestin2 recruitment assay. Journal of Biomolecular Screening. 10: 463-75. PMID 16093556 DOI: 10.1177/1087057105275344 |
0.792 |
|
| 2005 |
Zhu WZ, Chakir K, Zhang S, Yang D, Lavoie C, Bouvier M, Hébert TE, Lakatta EG, Cheng H, Xiao RP. Heterodimerization of beta1- and beta2-adrenergic receptor subtypes optimizes beta-adrenergic modulation of cardiac contractility. Circulation Research. 97: 244-51. PMID 16002745 DOI: 10.1161/01.Res.0000176764.38934.86 |
0.508 |
|
| 2005 |
Milligan G, Bouvier M. Methods to monitor the quaternary structure of G protein-coupled receptors. The Febs Journal. 272: 2914-25. PMID 15955052 DOI: 10.1111/J.1742-4658.2005.04731.X |
0.51 |
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| 2005 |
Urizar E, Montanelli L, Loy T, Bonomi M, Swillens S, Gales C, Bouvier M, Smits G, Vassart G, Costagliola S. Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity. The Embo Journal. 24: 1954-64. PMID 15889138 DOI: 10.1038/Sj.Emboj.7600686 |
0.756 |
|
| 2005 |
Galés C, Rebois RV, Hogue M, Trieu P, Breit A, Hébert TE, Bouvier M. Real-time monitoring of receptor and G-protein interactions in living cells. Nature Methods. 2: 177-84. PMID 15782186 DOI: 10.1038/Nmeth743 |
0.794 |
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| 2005 |
Charest PG, Terrillon S, Bouvier M. Monitoring agonist-promoted conformational changes of beta-arrestin in living cells by intramolecular BRET. Embo Reports. 6: 334-40. PMID 15776020 DOI: 10.1038/Sj.Embor.7400373 |
0.833 |
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| 2005 |
Bulenger S, Marullo S, Bouvier M. Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation. Trends in Pharmacological Sciences. 26: 131-7. PMID 15749158 DOI: 10.1016/J.Tips.2005.01.004 |
0.564 |
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| 2005 |
Percherancier Y, Berchiche YA, Slight I, Volkmer-Engert R, Tamamura H, Fujii N, Bouvier M, Heveker N. Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in CXCR4 homo- and heterodimers. The Journal of Biological Chemistry. 280: 9895-903. PMID 15632118 DOI: 10.1074/Jbc.M411151200 |
0.801 |
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| 2005 |
Villemure JF, Adam L, Bevan NJ, Gearing K, Chénier S, Bouvier M. Subcellular distribution of GABA(B) receptor homo- and hetero-dimers. The Biochemical Journal. 388: 47-55. PMID 15617512 DOI: 10.1042/Bj20041435 |
0.821 |
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| 2005 |
Piñeyro G, Azzi M, deLéan A, Schiller PW, Bouvier M. Reciprocal regulation of agonist and inverse agonist signaling efficacy upon short-term treatment of the human delta-opioid receptor with an inverse agonist. Molecular Pharmacology. 67: 336-48. PMID 15496503 DOI: 10.1124/Mol.104.004549 |
0.831 |
|
| 2004 |
Perroy J, Pontier S, Charest PG, Aubry M, Bouvier M. Real-time monitoring of ubiquitination in living cells by BRET. Nature Methods. 1: 203-8. PMID 15782195 DOI: 10.1038/Nmeth722 |
0.833 |
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| 2004 |
Granier S, Terrillon S, Pascal R, Déméné H, Bouvier M, Guillon G, Mendre C. A cyclic peptide mimicking the third intracellular loop of the V2 vasopressin receptor inhibits signaling through its interaction with receptor dimer and G protein. The Journal of Biological Chemistry. 279: 50904-14. PMID 15452133 DOI: 10.1074/Jbc.M405089200 |
0.816 |
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| 2004 |
Terrillon S, Bouvier M. Receptor activity-independent recruitment of betaarrestin2 reveals specific signalling modes. The Embo Journal. 23: 3950-61. PMID 15385966 DOI: 10.1038/Sj.Emboj.7600387 |
0.854 |
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| 2004 |
Qanbar R, Bouvier M. Determination of protein-bound palmitate turnover rates using a three-compartment model that formally incorporates [3H]palmitate recycling. Biochemistry. 43: 12275-88. PMID 15379566 DOI: 10.1021/Bi049176U |
0.791 |
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| 2004 |
Bernier V, Bichet DG, Bouvier M. Pharmacological chaperone action on G-protein-coupled receptors. Current Opinion in Pharmacology. 4: 528-33. PMID 15351360 DOI: 10.1016/J.Coph.2004.08.001 |
0.842 |
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| 2004 |
Registre M, Goetz JG, St Pierre P, Pang H, Lagacé M, Bouvier M, Le PU, Nabi IR. The gene product of the gp78/AMFR ubiquitin E3 ligase cDNA is selectively recognized by the 3F3A antibody within a subdomain of the endoplasmic reticulum. Biochemical and Biophysical Research Communications. 320: 1316-22. PMID 15303277 DOI: 10.1016/J.Bbrc.2004.06.089 |
0.343 |
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| 2004 |
Denis M, Haidar B, Marcil M, Bouvier M, Krimbou L, Genest J. Characterization of oligomeric human ATP binding cassette transporter A1. Potential implications for determining the structure of nascent high density lipoprotein particles. The Journal of Biological Chemistry. 279: 41529-36. PMID 15280376 DOI: 10.1074/Jbc.M406881200 |
0.689 |
|
| 2004 |
Bernier V, Lagacé M, Bichet DG, Bouvier M. Pharmacological chaperones: potential treatment for conformational diseases. Trends in Endocrinology and Metabolism: Tem. 15: 222-8. PMID 15223052 DOI: 10.1016/J.Tem.2004.05.003 |
0.782 |
|
| 2004 |
Ferré S, Ciruela F, Canals M, Marcellino D, Burgueno J, Casadó V, Hillion J, Torvinen M, Fanelli F, Benedetti Pd Pd, Goldberg SR, Bouvier M, Fuxe K, Agnati LF, Lluis C, et al. Adenosine A2A-dopamine D2 receptor-receptor heteromers. Targets for neuro-psychiatric disorders. Parkinsonism & Related Disorders. 10: 265-71. PMID 15196504 DOI: 10.1016/J.Parkreldis.2004.02.014 |
0.467 |
|
| 2004 |
Bernier V, Lagacé M, Lonergan M, Arthus MF, Bichet DG, Bouvier M. Functional rescue of the constitutively internalized V2 vasopressin receptor mutant R137H by the pharmacological chaperone action of SR49059. Molecular Endocrinology (Baltimore, Md.). 18: 2074-84. PMID 15166253 DOI: 10.1210/Me.2004-0080 |
0.833 |
|
| 2004 |
Salahpour A, Angers S, Mercier JF, Lagacé M, Marullo S, Bouvier M. Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting. The Journal of Biological Chemistry. 279: 33390-7. PMID 15155738 DOI: 10.1074/Jbc.M403363200 |
0.857 |
|
| 2004 |
Breit A, Lagacé M, Bouvier M. Hetero-oligomerization between beta2- and beta3-adrenergic receptors generates a beta-adrenergic signaling unit with distinct functional properties. The Journal of Biological Chemistry. 279: 28756-65. PMID 15123695 DOI: 10.1074/Jbc.M313310200 |
0.695 |
|
| 2004 |
Terrillon S, Barberis C, Bouvier M. Heterodimerization of V1a and V2 vasopressin receptors determines the interaction with beta-arrestin and their trafficking patterns. Proceedings of the National Academy of Sciences of the United States of America. 101: 1548-53. PMID 14757828 DOI: 10.1073/Pnas.0305322101 |
0.834 |
|
| 2004 |
Canals M, Burgueño J, Marcellino D, Cabello N, Canela EI, Mallol J, Agnati L, Ferré S, Bouvier M, Fuxe K, Ciruela F, Lluis C, Franco R. Homodimerization of adenosine A2A receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer. Journal of Neurochemistry. 88: 726-34. PMID 14720222 DOI: 10.1046/J.1471-4159.2003.02200.X |
0.481 |
|
| 2004 |
Terrillon S, Bouvier M. Roles of G-protein-coupled receptor dimerization. Embo Reports. 5: 30-4. PMID 14710183 DOI: 10.1038/Sj.Embor.7400052 |
0.848 |
|
| 2004 |
Kaykas A, Yang-Snyder J, Héroux M, Shah KV, Bouvier M, Moon RT. Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization. Nature Cell Biology. 6: 52-8. PMID 14688793 DOI: 10.1038/Ncb1081 |
0.591 |
|
| 2004 |
Denis M, Haidar B, Marcil M, Bouvier M, Krimbou L, Genest J. Molecular and cellular physiology of apolipoprotein A-I lipidation by the ATP-binding cassette transporter A1 (ABCA1). The Journal of Biological Chemistry. 279: 7384-94. PMID 14660648 DOI: 10.1074/Jbc.M306963200 |
0.695 |
|
| 2003 |
Azzi M, Charest PG, Angers S, Rousseau G, Kohout T, Bouvier M, Piñeyro G. Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors. Proceedings of the National Academy of Sciences of the United States of America. 100: 11406-11. PMID 13679574 DOI: 10.1073/Pnas.1936664100 |
0.855 |
|
| 2003 |
Canals M, Marcellino D, Fanelli F, Ciruela F, de Benedetti P, Goldberg SR, Neve K, Fuxe K, Agnati LF, Woods AS, Ferré S, Lluis C, Bouvier M, Franco R. Adenosine A2A-dopamine D2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer. The Journal of Biological Chemistry. 278: 46741-9. PMID 12933819 DOI: 10.1074/Jbc.M306451200 |
0.483 |
|
| 2003 |
Charest PG, Bouvier M. Palmitoylation of the V2 vasopressin receptor carboxyl tail enhances beta-arrestin recruitment leading to efficient receptor endocytosis and ERK1/2 activation. The Journal of Biological Chemistry. 278: 41541-51. PMID 12900404 DOI: 10.1074/Jbc.M306589200 |
0.826 |
|
| 2003 |
Perroy J, Adam L, Qanbar R, Chénier S, Bouvier M. Phosphorylation-independent desensitization of GABA(B) receptor by GRK4. The Embo Journal. 22: 3816-24. PMID 12881416 DOI: 10.1093/Emboj/Cdg383 |
0.833 |
|
| 2003 |
Denis M, Bissonnette R, Haidar B, Krimbou L, Bouvier M, Genest J. Expression, regulation, and activity of ABCA1 in human cell lines. Molecular Genetics and Metabolism. 78: 265-74. PMID 12706378 DOI: 10.1016/S1096-7192(03)00020-9 |
0.685 |
|
| 2003 |
Germain-Desprez D, Bazinet M, Bouvier M, Aubry M. Oligomerization of transcriptional intermediary factor 1 regulators and interaction with ZNF74 nuclear matrix protein revealed by bioluminescence resonance energy transfer in living cells. The Journal of Biological Chemistry. 278: 22367-73. PMID 12684500 DOI: 10.1074/Jbc.M302234200 |
0.381 |
|
| 2003 |
Salahpour A, Bonin H, Bhalla S, Petäjä-Repo U, Bouvier M. Biochemical characterization of beta2-adrenergic receptor dimers and oligomers. Biological Chemistry. 384: 117-23. PMID 12674505 DOI: 10.1515/Bc.2003.012 |
0.843 |
|
| 2003 |
Terrillon S, Durroux T, Mouillac B, Breit A, Ayoub MA, Taulan M, Jockers R, Barberis C, Bouvier M. Oxytocin and vasopressin V1a and V2 receptors form constitutive homo- and heterodimers during biosynthesis. Molecular Endocrinology (Baltimore, Md.). 17: 677-91. PMID 12554793 DOI: 10.1210/Me.2002-0222 |
0.858 |
|
| 2003 |
Qanbar R, Bouvier M. Role of palmitoylation/depalmitoylation reactions in G-protein-coupled receptor function. Pharmacology & Therapeutics. 97: 1-33. PMID 12493533 DOI: 10.1016/S0163-7258(02)00300-5 |
0.851 |
|
| 2002 |
Bertrand L, Parent S, Caron M, Legault M, Joly E, Angers S, Bouvier M, Brown M, Houle B, Ménard L. The BRET2/arrestin assay in stable recombinant cells: a platform to screen for compounds that interact with G protein-coupled receptors (GPCRS). Journal of Receptor and Signal Transduction Research. 22: 533-41. PMID 12503639 DOI: 10.1081/Rrs-120014619 |
0.85 |
|
| 2002 |
Lavine N, Ethier N, Oak JN, Pei L, Liu F, Trieu P, Rebois RV, Bouvier M, Hebert TE, Van Tol HH. G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclase. The Journal of Biological Chemistry. 277: 46010-9. PMID 12297500 DOI: 10.1074/Jbc.M205035200 |
0.552 |
|
| 2002 |
Mercier JF, Salahpour A, Angers S, Breit A, Bouvier M. Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer. The Journal of Biological Chemistry. 277: 44925-31. PMID 12244098 DOI: 10.1074/Jbc.M205767200 |
0.837 |
|
| 2002 |
Lavoie C, Mercier JF, Salahpour A, Umapathy D, Breit A, Villeneuve LR, Zhu WZ, Xiao RP, Lakatta EG, Bouvier M, Hébert TE. Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy. The Journal of Biological Chemistry. 277: 35402-10. PMID 12140284 DOI: 10.1074/Jbc.M204163200 |
0.82 |
|
| 2002 |
Issafras H, Angers S, Bulenger S, Blanpain C, Parmentier M, Labbé-Jullié C, Bouvier M, Marullo S. Constitutive agonist-independent CCR5 oligomerization and antibody-mediated clustering occurring at physiological levels of receptors. The Journal of Biological Chemistry. 277: 34666-73. PMID 12089144 DOI: 10.1074/Jbc.M202386200 |
0.727 |
|
| 2002 |
Ayoub MA, Couturier C, Lucas-Meunier E, Angers S, Fossier P, Bouvier M, Jockers R. Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer. The Journal of Biological Chemistry. 277: 21522-8. PMID 11940583 DOI: 10.1074/Jbc.M200729200 |
0.711 |
|
| 2002 |
Petäjä-Repo UE, Hogue M, Bhalla S, Laperrière A, Morello JP, Bouvier M. Ligands act as pharmacological chaperones and increase the efficiency of delta opioid receptor maturation. The Embo Journal. 21: 1628-37. PMID 11927547 DOI: 10.1093/Emboj/21.7.1628 |
0.853 |
|
| 2002 |
Barbas D, Zappulla JP, Angers S, Bouvier M, Castellucci VF, DesGroseillers L. Functional characterization of a novel serotonin receptor (5-HTap2) expressed in the CNS of Aplysia californica. Journal of Neurochemistry. 80: 335-45. PMID 11902124 DOI: 10.1046/J.0022-3042.2001.00703.X |
0.715 |
|
| 2002 |
Angers S, Salahpour A, Bouvier M. Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function. Annual Review of Pharmacology and Toxicology. 42: 409-35. PMID 11807178 DOI: 10.1146/Annurev.Pharmtox.42.091701.082314 |
0.84 |
|
| 2002 |
Bouvier M. Oligomeric assembly of G protein-coupled receptors: Role in receptor trafficking and function Gbm Annual Fall Meeting Halle 2002. 2002. DOI: 10.1240/sav_gbm_2002_h_000236 |
0.444 |
|
| 2001 |
Azzi M, Piñeyro G, Pontier S, Parent S, Ansanay H, Bouvier M. Allosteric effects of G protein overexpression on the binding of beta-adrenergic ligands with distinct inverse efficacies. Molecular Pharmacology. 60: 999-1007. PMID 11641428 DOI: 10.1124/Mol.60.5.999 |
0.831 |
|
| 2001 |
Carpentier E, Lebesgue D, Kamen AA, Hogue M, Bouvier M, Durocher Y. Increased production of active human beta(2)-adrenergic/G(alphas) fusion receptor in Sf-9 cells using nutrient limiting conditions. Protein Expression and Purification. 23: 66-74. PMID 11570847 DOI: 10.1006/Prep.2001.1476 |
0.699 |
|
| 2001 |
Hilairet S, Bélanger C, Bertrand J, Laperrière A, Foord SM, Bouvier M. Agonist-promoted internalization of a ternary complex between calcitonin receptor-like receptor, receptor activity-modifying protein 1 (RAMP1), and beta-arrestin. The Journal of Biological Chemistry. 276: 42182-90. PMID 11535606 DOI: 10.1074/Jbc.M107323200 |
0.865 |
|
| 2001 |
Rousseau G, Haddad PS, Gallo-Payet N, Bouvier M. Ca(2+)-dependent sensitization of adenylyl cyclase activity. European Journal of Pharmacology. 422: 53-60. PMID 11430913 DOI: 10.1016/S0014-2999(01)01073-1 |
0.587 |
|
| 2001 |
Bélanger C, Ansanay H, Qanbar R, Bouvier M. Primary sequence requirements for S-acylation of beta(2)-adrenergic receptor peptides. Febs Letters. 499: 59-64. PMID 11418112 DOI: 10.1016/S0014-5793(01)02513-3 |
0.803 |
|
| 2001 |
Morello JP, Salahpour A, Petäjä-Repo UE, Laperrière A, Lonergan M, Arthus MF, Nabi IR, Bichet DG, Bouvier M. Association of calnexin with wild type and mutant AVPR2 that causes nephrogenic diabetes insipidus. Biochemistry. 40: 6766-75. PMID 11389590 DOI: 10.1021/Bi002699R |
0.834 |
|
| 2001 |
Hilairet S, Foord SM, Marshall FH, Bouvier M. Protein-protein interaction and not glycosylation determines the binding selectivity of heterodimers between the calcitonin receptor-like receptor and the receptor activity-modifying proteins. The Journal of Biological Chemistry. 276: 29575-81. PMID 11387328 DOI: 10.1074/Jbc.M102722200 |
0.855 |
|
| 2001 |
Angers S, Salahpour A, Bouvier M. Biochemical and biophysical demonstration of GPCR oligomerization in mammalian cells. Life Sciences. 68: 2243-50. PMID 11358333 DOI: 10.1016/S0024-3205(01)01012-8 |
0.839 |
|
| 2001 |
Bouvier M. Oligomerization of G-protein-coupled transmitter receptors. Nature Reviews. Neuroscience. 2: 274-86. PMID 11283750 DOI: 10.1038/35067575 |
0.548 |
|
| 2001 |
Laurent CE, Cardinal R, Rousseau G, Vermeulen M, Bouchard C, Wilkinson M, Armour JA, Bouvier M. Functional desensitization to isoproterenol without reducing cAMP production in canine failing cardiocytes. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 280: R355-64. PMID 11208562 DOI: 10.1152/Ajpregu.2001.280.2.R355 |
0.62 |
|
| 2001 |
Moffett S, Rousseau G, Lagacé M, Bouvier M. The palmitoylation state of the beta(2)-adrenergic receptor regulates the synergistic action of cyclic AMP-dependent protein kinase and beta-adrenergic receptor kinase involved in its phosphorylation and desensitization. Journal of Neurochemistry. 76: 269-79. PMID 11146000 DOI: 10.1046/J.1471-4159.2001.00005.X |
0.821 |
|
| 2001 |
Petaja-Repo UE, Hogue M, Laperriere A, Bhalla S, Walker P, Bouvier M. Newly synthesized human delta opioid receptors retained in the endoplasmic reticulum are retrotranslocated to the cytosol, deglycosylated, ubiquitinated, and degraded by the proteasome. The Journal of Biological Chemistry. 276: 4416-23. PMID 11054417 DOI: 10.1074/Jbc.M007151200 |
0.831 |
|
| 2001 |
Boucher M, Laurent C, Bouvier M, Cardinal R, Rousseau G. Cardiomyocytes β-adrenergic receptors are resistants to short-term desensitization Journal of Molecular and Cellular Cardiology. 33: A15. DOI: 10.1016/S0022-2828(01)90058-6 |
0.786 |
|
| 2000 |
Morello JP, Petäjä-Repo UE, Bichet DG, Bouvier M. Pharmacological chaperones: a new twist on receptor folding. Trends in Pharmacological Sciences. 21: 466-9. PMID 11121835 DOI: 10.1016/S0165-6147(00)01575-3 |
0.813 |
|
| 2000 |
Angers S, Bouvier M. Reply: beyond receptor dimerization Trends in Pharmacological Sciences. 21: 326. PMID 10973077 DOI: 10.1016/S0165-6147(00)01518-2 |
0.684 |
|
| 2000 |
Salahpour A, Angers S, Bouvier M. Functional significance of oligomerization of G-protein-coupled receptors. Trends in Endocrinology and Metabolism: Tem. 11: 163-8. PMID 10856916 DOI: 10.1016/S1043-2760(00)00260-5 |
0.831 |
|
| 2000 |
Petaja-Repo UE, Hogue M, Laperriere A, Walker P, Bouvier M. Export from the endoplasmic reticulum represents the limiting step in the maturation and cell surface expression of the human delta opioid receptor. The Journal of Biological Chemistry. 275: 13727-36. PMID 10788493 DOI: 10.1074/Jbc.275.18.13727 |
0.51 |
|
| 2000 |
Morello JP, Salahpour A, Laperrière A, Bernier V, Arthus MF, Lonergan M, Petäjä-Repo U, Angers S, Morin D, Bichet DG, Bouvier M. Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants. The Journal of Clinical Investigation. 105: 887-95. PMID 10749568 DOI: 10.1172/Jci8688 |
0.832 |
|
| 2000 |
Angers S, Salahpour A, Joly E, Hilairet S, Chelsky D, Dennis M, Bouvier M. Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET). Proceedings of the National Academy of Sciences of the United States of America. 97: 3684-9. PMID 10725388 DOI: 10.1073/Pnas.97.7.3684 |
0.859 |
|
| 2000 |
Bouvier M, Laporte S, Lagacé M, Caron M. Échafaudages protéiques et signalisation modulaire via les récepteurs à sept domaines transmembranaires : au-delà des protéines G. MéDecine/Sciences. 16: 644. DOI: 10.4267/10608/2054 |
0.308 |
|
| 2000 |
Morello J, Bernier V, Bouvier M, Bichet D. Des chaperons pharmacologiques pour corriger le diabète insipide néphrogénique ? MéDecine/Sciences. 16: 1109. DOI: 10.4267/10608/1534 |
0.747 |
|
| 1999 |
Loisel TP, Ansanay H, Adam L, Marullo S, Seifert R, Lagacé M, Bouvier M. Activation of the beta(2)-adrenergic receptor-Galpha(s) complex leads to rapid depalmitoylation and inhibition of repalmitoylation of both the receptor and Galpha(s). The Journal of Biological Chemistry. 274: 31014-9. PMID 10521499 DOI: 10.1074/Jbc.274.43.31014 |
0.859 |
|
| 1999 |
Jockers R, Angers S, Da Silva A, Benaroch P, Strosberg AD, Bouvier M, Marullo S. Beta(2)-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis. The Journal of Biological Chemistry. 274: 28900-8. PMID 10506134 DOI: 10.1074/Jbc.274.41.28900 |
0.7 |
|
| 1999 |
Adam L, Bouvier M, Jones TL. Nitric oxide modulates beta(2)-adrenergic receptor palmitoylation and signaling. The Journal of Biological Chemistry. 274: 26337-43. PMID 10473590 DOI: 10.1074/jbc.274.37.26337 |
0.613 |
|
| 1999 |
Marquis M, Fenrick R, Pedro L, Bouvier M, De Léan A. Comparative binding study of rat natriuretic peptide receptor-A. Molecular and Cellular Biochemistry. 194: 23-30. PMID 10391120 DOI: 10.1023/A:1006835808554 |
0.378 |
|
| 1999 |
Bouvier M, Angers S. Nouveaux échafaudages protéiques modulaires pour les récepteurs couplés aux protéines G. MéDecine/Sciences. 15: 741. DOI: 10.4267/10608/1423 |
0.576 |
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| 1998 |
Bouvier M, Ménard L, Dennis M, Marullo S. Expression and recovery of functional G-protein-coupled receptors using baculovirus expression systems. Current Opinion in Biotechnology. 9: 522-7. PMID 9821283 DOI: 10.1016/S0958-1669(98)80040-2 |
0.509 |
|
| 1998 |
Bunnett NW, Bouvier M, De Blasi A. Peptide G protein-coupled receptors meet at Erice. Trends in Pharmacological Sciences. 19: 343-6. PMID 9786019 DOI: 10.1016/S0165-6147(98)01236-X |
0.456 |
|
| 1998 |
Hébert TE, Bouvier M. Structural and functional aspects of G protein-coupled receptor oligomerization. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 76: 1-11. PMID 9666301 DOI: 10.1139/Bcb-76-1-1 |
0.566 |
|
| 1998 |
Hebert TE, Loisel TP, Adam L, Ethier N, Onge SS, Bouvier M. Functional rescue of a constitutively desensitized beta2AR through receptor dimerization. The Biochemical Journal. 330: 287-93. PMID 9461522 DOI: 10.1042/Bj3300287 |
0.705 |
|
| 1998 |
Bouvier M, Rousseau G. Subtype-specific regulation of the beta-adrenergic receptors. Advances in Pharmacology (San Diego, Calif.). 42: 433-8. PMID 9327932 DOI: 10.1016/S1054-3589(08)60781-4 |
0.675 |
|
| 1997 |
Loisel TP, Ansanay H, St-Onge S, Gay B, Boulanger P, Strosberg AD, Marullo S, Bouvier M. Recovery of homogeneous and functional beta 2-adrenergic receptors from extracellular baculovirus particles. Nature Biotechnology. 15: 1300-4. PMID 9359116 DOI: 10.1038/nbt1197-1300 |
0.843 |
|
| 1997 |
Lacroix A, Tremblay J, Rousseau G, Bouvier M, Hamet P. Propranolol therapy for ectopic beta-adrenergic receptors in adrenal Cushing's syndrome. The New England Journal of Medicine. 337: 1429-34. PMID 9358140 DOI: 10.1056/Nejm199711133372004 |
0.623 |
|
| 1997 |
Murphy RJ, Gardiner PF, Rousseau G, Bouvier M, Béliveau L. Chronic beta-blockade increases skeletal muscle beta-adrenergic-receptor density and enhances contractile force. Journal of Applied Physiology (Bethesda, Md. : 1985). 83: 459-65. PMID 9262441 DOI: 10.1152/Jappl.1997.83.2.459 |
0.642 |
|
| 1997 |
Rousseau G, Guilbault N, Da Silva A, Mouillac B, Chidiac P, Bouvier M. Influence of receptor density on the patterns of beta2-adrenocepter desensitization. European Journal of Pharmacology. 326: 75-84. PMID 9178658 DOI: 10.1016/S0014-2999(97)00138-6 |
0.832 |
|
| 1997 |
Bouvier M. Increased pressure on G protein-coupled receptor kinases. The Journal of Clinical Investigation. 99: 2060-1. PMID 9151775 DOI: 10.1172/Jci119376 |
0.462 |
|
| 1997 |
Beaulieu M, Brakier-Gingras L, Bouvier M. Upregulation of alpha1A- and alpha1B-adrenergic receptor mRNAs in the heart of cardiomyopathic hamsters. Journal of Molecular and Cellular Cardiology. 29: 111-9. PMID 9040026 DOI: 10.1006/Jmcc.1996.0256 |
0.747 |
|
| 1996 |
Loisel TP, Adam L, Hebert TE, Bouvier M. Agonist stimulation increases the turnover rate of beta 2AR-bound palmitate and promotes receptor depalmitoylation. Biochemistry. 35: 15923-32. PMID 8961959 DOI: 10.1021/Bi9611321 |
0.711 |
|
| 1996 |
Morello JP, Bouvier M. Palmitoylation: a post-translational modification that regulates signalling from G-protein coupled receptors. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 74: 449-57. PMID 8960351 DOI: 10.1139/O96-049 |
0.852 |
|
| 1996 |
Raymond P, Bouvier M, Drapeau G, Blais C, Morais R, Adam A. Bradykinin decreases T-kininogen synthesis in a rat hepatoma cell line: evidence of bradykinin B2-type receptors. Peptides. 17: 1171-6. PMID 8959752 DOI: 10.1016/S0196-9781(96)00180-5 |
0.332 |
|
| 1996 |
Ming M, Chan W, Wang TT, Roberts KD, Bouvier M, Lachance S, Carrière S, Chan JS. beta-Adrenoceptors and dexamethasone synergistically stimulate the expression of the angiotensinogen gene in opossum kidney cells. Kidney International. 50: 94-101. PMID 8807577 DOI: 10.1038/Ki.1996.291 |
0.321 |
|
| 1996 |
Chidiac P, Nouet S, Bouvier M. Agonist-induced modulation of inverse agonist efficacy at the beta 2-adrenergic receptor. Molecular Pharmacology. 50: 662-9. PMID 8794908 |
0.395 |
|
| 1996 |
Yoshikawa T, Port JD, Asano K, Chidiak P, Bouvier M, Dutcher D, Roden RL, Minobe W, Tremmel KD, Bristow MR. Cardiac adrenergic receptor effects of carvedilol. European Heart Journal. 17: 8-16. PMID 8733065 DOI: 10.1093/Eurheartj/17.Suppl_B.8 |
0.438 |
|
| 1996 |
Moffett S, Adam L, Bonin H, Loisel TP, Bouvier M, Mouillac B. Palmitoylated cysteine 341 modulates phosphorylation of the beta2-adrenergic receptor by the cAMP-dependent protein kinase. The Journal of Biological Chemistry. 271: 21490-7. PMID 8702933 DOI: 10.1074/Jbc.271.35.21490 |
0.848 |
|
| 1996 |
Hebert TE, Moffett S, Morello JP, Loisel TP, Bichet DG, Barret C, Bouvier M. A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation. The Journal of Biological Chemistry. 271: 16384-92. PMID 8663163 DOI: 10.1074/Jbc.271.27.16384 |
0.863 |
|
| 1996 |
Jockers R, Da Silva A, Strosberg AD, Bouvier M, Marullo S. New molecular and structural determinants involved in beta 2-adrenergic receptor desensitization and sequestration. Delineation using chimeric beta 3/beta 2-adrenergic receptors. The Journal of Biological Chemistry. 271: 9355-62. PMID 8621600 DOI: 10.1074/Jbc.271.16.9355 |
0.432 |
|
| 1996 |
Rousseau G, Nantel F, Bouvier M. Distinct receptor domains determine subtype-specific coupling and desensitization phenotypes for human beta1- and beta2-adrenergic receptors. Molecular Pharmacology. 49: 752-60. PMID 8609905 |
0.309 |
|
| 1996 |
Feldman RD, Bouvier M. [19] Crosstalk between tyrosine kinase and G-protein-linked signal transduction systems Methods in Neurosciences. 29: 280-297. DOI: 10.1016/S1043-9471(96)80055-3 |
0.518 |
|
| 1995 |
Bouvier M, Loisel TP, Hebert T. Dynamic regulation of G-protein coupled receptor palmitoylation: potential role in receptor function. Biochemical Society Transactions. 23: 577-81. PMID 8566420 DOI: 10.1042/Bst0230577 |
0.535 |
|
| 1995 |
Valiquette M, Parent S, Loisel TP, Bouvier M. Mutation of tyrosine-141 inhibits insulin-promoted tyrosine phosphorylation and increased responsiveness of the human beta 2-adrenergic receptor. The Embo Journal. 14: 5542-9. PMID 8521811 DOI: 10.1002/J.1460-2075.1995.Tb00241.X |
0.81 |
|
| 1995 |
Nantel F, Bouvier M, Strosberg AD, Marullo S. Functional effects of long-term activation on human beta 2- and beta 3-adrenoceptor signalling. British Journal of Pharmacology. 114: 1045-51. PMID 7780639 DOI: 10.1111/J.1476-5381.1995.Tb13311.X |
0.759 |
|
| 1995 |
Marullo S, Nantel F, Strosberg AD, Bouvier M. Variability in the regulation of beta-adrenoceptor subtypes. Biochemical Society Transactions. 23: 126-9. PMID 7758687 DOI: 10.1042/Bst0230126 |
0.712 |
|
| 1995 |
Bouvier M, Moffett S, Loisel TP, Mouillac B, Hebert T, Chidiac P. Palmitoylation of G-protein-coupled receptors: a dynamic modification with functional consequences. Biochemical Society Transactions. 23: 116-20. PMID 7758677 DOI: 10.1042/Bst0230116 |
0.819 |
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| 1995 |
Bouvier M, Chidiac P, Hebert TE, Loisel TP, Moffett S, Mouillac B. Dynamic palmitoylation of G-protein-coupled receptors in eukaryotic cells. Methods in Enzymology. 250: 300-14. PMID 7651160 DOI: 10.1016/0076-6879(95)50080-4 |
0.861 |
|
| 1995 |
Labrecque J, Fargin A, Bouvier M, Chidiac P, Dennis M. Serotonergic antagonists differentially inhibit spontaneous activity and decrease ligand binding capacity of the rat 5-hydroxytryptamine type 2C receptor in Sf9 cells. Molecular Pharmacology. 48: 150-9. PMID 7623769 |
0.383 |
|
| 1995 |
Varma DR, Deng XF, Chemtob S, Nantel F, Bouvier M. Characterization of the vasorelaxant activity of tyramine and other phenylethylamines in rat aorta. Canadian Journal of Physiology and Pharmacology. 73: 742-6. PMID 7585347 DOI: 10.1139/Y95-097 |
0.75 |
|
| 1995 |
Ng GY, Trogadis J, Stevens J, Bouvier M, O'Dowd BF, George SR. Agonist-induced desensitization of dopamine D1 receptor-stimulated adenylyl cyclase activity is temporally and biochemically separated from D1 receptor internalization. Proceedings of the National Academy of Sciences of the United States of America. 92: 10157-61. PMID 7479745 DOI: 10.1073/Pnas.92.22.10157 |
0.688 |
|
| 1995 |
Bouvier M, Nantel F, Valiquette M, Moffett S, Mouillac B. Le récepteur β2-adrénergique. Un modèle d'étude des mécanismes moléculaires de la désensibilisation MéDecine/Sciences. 11: 819. DOI: 10.4267/10608/2293 |
0.773 |
|
| 1994 |
Nantel F, Marullo S, Krief S, Strosberg AD, Bouvier M. Cell-specific down-regulation of the beta 3-adrenergic receptor. The Journal of Biological Chemistry. 269: 13148-55. PMID 8175742 |
0.386 |
|
| 1994 |
Marchetti B, Morale MC, Paradis P, Bouvier M. Characterization, expression, and hormonal control of a thymic beta 2-adrenergic receptor. The American Journal of Physiology. 267: E718-31. PMID 7977723 DOI: 10.1152/Ajpendo.1994.267.5.E718 |
0.373 |
|
| 1994 |
Chidiac P, Hebert TE, Valiquette M, Dennis M, Bouvier M. Inverse agonist activity of beta-adrenergic antagonists. Molecular Pharmacology. 45: 490-9. PMID 7908406 |
0.343 |
|
| 1994 |
St-Onge S, Chidiac P, Brakier-Gingras L, Bouvier M. Beta-adrenergic receptor desensitization in the early stage of hereditary cardiomyopathy in hamsters. Canadian Journal of Physiology and Pharmacology. 72: 875-83. PMID 7834576 DOI: 10.1139/Y94-124 |
0.822 |
|
| 1994 |
Ng GY, Mouillac B, George SR, Caron M, Dennis M, Bouvier M, O'Dowd BF. Desensitization, phosphorylation and palmitoylation of the human dopamine D1 receptor. European Journal of Pharmacology. 267: 7-19. PMID 7515822 DOI: 10.1016/0922-4106(94)90219-4 |
0.755 |
|
| 1993 |
Valiquette M, Bonin H, Bouvier M. Mutation of tyrosine-350 impairs the coupling of the beta 2-adrenergic receptor to the stimulatory guanine nucleotide binding protein without interfering with receptor down-regulation. Biochemistry. 32: 4979-85. PMID 8388251 DOI: 10.1021/Bi00070A002 |
0.849 |
|
| 1993 |
Ng GYK, George SR, Zastawny RL, Caron M, Bouvier M, Dennis M, O'Dowd BF. Human serotonin(1B) receptor expression in Sf9 cells: Phosphorylation, palmitoylation, and adenylyl cyclase inhibition Biochemistry. 32: 11727-11733. PMID 8218242 DOI: 10.1021/Bi00094A032 |
0.652 |
|
| 1993 |
Nantel F, Bouvier M. Chapter 3 Receptor regulation New Comprehensive Biochemistry. 24: 99-109. DOI: 10.1016/S0167-7306(08)60356-7 |
0.823 |
|
| 1993 |
Moffett S, Mouillac B, Bonin H, Bouvier M. Altered phosphorylation and desensitization patterns of a human beta 2-adrenergic receptor lacking the palmitoylated Cys341. The Embo Journal. 12: 349-356. DOI: 10.1002/j.1460-2075.1993.tb05663.x |
0.316 |
|
| 1991 |
Bouvier M, Guilbault N, Bonin H. Phorbol-ester-induced phosphorylation of the β2-adrenergic receptor decreases its coupling to Gs Febs Letters. 279: 243-248. PMID 1848190 DOI: 10.1016/0014-5793(91)80159-Z |
0.846 |
|
| 1991 |
Calderone A, Bouvier M, Li K, Juneau C, De Champlain J, Rouleau JL. Dysfunction of the β- and α-adrenergic systems in a model of congestive heart failure: The pacing-overdrive dog Circulation Research. 69: 332-343. PMID 1650296 DOI: 10.1161/01.Res.69.2.332 |
0.357 |
|
| 1990 |
Collins S, Bouvier M, Lohse MJ, Benovic JL, Caron MG, Lefkowitz RJ. Mechanisms involved in adrenergic receptor desensitization. Biochemical Society Transactions. 18: 541-4. PMID 2177406 DOI: 10.1042/Bst0180541 |
0.869 |
|
| 1990 |
Bouvier M. Cross‐Talk between Second Messengers Annals of the New York Academy of Sciences. 594: 120-129. PMID 2165756 DOI: 10.1111/J.1749-6632.1990.Tb40473.X |
0.47 |
|
| 1990 |
Valiquette M, Bonin H, Hnatowich M, Caron MG, Lefkowitz RJ, Bouvier M. Involvement of tyrosine residues located in the carboxyl tail of the human beta 2-adrenergic receptor in agonist-induced down-regulation of the receptor. Proceedings of the National Academy of Sciences of the United States of America. 87: 5089-93. PMID 2164220 DOI: 10.1073/Pnas.87.13.5089 |
0.844 |
|
| 1990 |
Hausdorff WP, Lohse MJ, Bouvier M, Liggett SB, Caron MG, Lefkowitz RJ. Two kinases mediate agonist-dependent phosphorylation and desensitization of the beta 2-adrenergic receptor. Symposia of the Society For Experimental Biology. 44: 225-40. PMID 1983369 |
0.676 |
|
| 1989 |
Liggett SB, Bouvier M, O'Dowd BF, Caron MG, Lefkowitz RJ, DeBlasi A. Substitution of an extracellular cysteine in the beta 2-adrenergic receptor enhances agonist-promoted phosphorylation and receptor desensitization. Biochemical and Biophysical Research Communications. 165: 257-63. PMID 2556136 DOI: 10.1016/0006-291X(89)91063-2 |
0.835 |
|
| 1989 |
Liggett SB, Bouvier M, Hausdorff WP, O'Dowd B, Caron MG, Lefkowitz RJ. Altered patterns of agonist-stimulated cAMP accumulation in cells expressing mutant beta 2-adrenergic receptors lacking phosphorylation sites. Molecular Pharmacology. 36: 641-6. PMID 2554115 |
0.557 |
|
| 1989 |
Hausdorff WP, Bouvier M, O'Dowd BF, Irons GP, Caron MG, Lefkowitz RJ. Phosphorylation sites on two domains of the beta 2-adrenergic receptor are involved in distinct pathways of receptor desensitization. The Journal of Biological Chemistry. 264: 12657-65. PMID 2545714 |
0.53 |
|
| 1989 |
O'Dowd BF, Hnatowich M, Caron MG, Lefkowitz RJ, Bouvier M. Palmitoylation of the human beta 2-adrenergic receptor. Mutation of Cys341 in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor. The Journal of Biological Chemistry. 264: 7564-9. PMID 2540197 |
0.57 |
|
| 1989 |
Bouvier M, Collins S, O'Dowd BF, Campbell PT, de Blasi A, Kobilka BK, MacGregor C, Irons GP, Caron MG, Lefkowitz RJ. Two distinct pathways for cAMP-mediated down-regulation of the beta 2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level. The Journal of Biological Chemistry. 264: 16786-92. PMID 2476447 |
0.637 |
|
| 1989 |
Collins S, Bouvier M, Bolanowski MA, Caron MG, Lefkowitz RJ. cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure. Proceedings of the National Academy of Sciences of the United States of America. 86: 4853-7. PMID 2472635 DOI: 10.1073/Pnas.86.13.4853 |
0.806 |
|
| 1989 |
Caron MG, Kobilka BK, Bouvier M, Hausdorff WP, Benovic JL, Lohse M, Cotecchia S, Regan JW, Fargin A, Raymond JR, Lefkowitz RJ. Catecholamine Receptors: Structure, Function, and Regulation Recent Progress in Hormone Research. 48: 195-200. DOI: 10.1007/978-3-642-75022-9_21 |
0.833 |
|
| 1988 |
Lefkowitz RJ, Kobilka BK, Benovic JL, Bouvier M, Cotecchia S, Hausdorff WP, Dohlman HG, Regan JW, Caron MG. Molecular biology of adrenergic receptors. Cold Spring Harbor Symposia On Quantitative Biology. 53: 507-14. PMID 2855490 DOI: 10.1101/Sqb.1988.053.01.058 |
0.836 |
|
| 1988 |
Benovic JL, Bouvier M, Caron MG, Lefkowitz RJ. Regulation of adenylyl cyclase-coupled beta-adrenergic receptors. Annual Review of Cell Biology. 4: 405-28. PMID 2848553 DOI: 10.1146/Annurev.Cb.04.110188.002201 |
0.774 |
|
| 1988 |
Hauber J, Bouvier M, Malim MH, Cullen BR. Phosphorylation of the rev gene product of human immunodeficiency virus type 1 Journal of Virology. 62: 4801-4804. PMID 2846891 DOI: 10.1128/Jvi.62.12.4801-4804.1988 |
0.373 |
|
| 1988 |
Bouvier M, Hausdorff WP, De Blasi A, O'Dowd BF, Kobilka BK, Caron MG, Lefkowitz RJ. Removal of phosphorylation sites from the beta 2-adrenergic receptor delays onset of agonist-promoted desensitization. Nature. 333: 370-3. PMID 2836733 DOI: 10.1038/333370A0 |
0.766 |
|
| 1988 |
Bouvier M, Hnatowich M, Collins S, Kobilka BK, Deblasi A, Lefkowitz RJ, Caron MG. Expression of a human cDNA encoding the beta 2-adrenergic receptor in Chinese hamster fibroblasts (CHW): functionality and regulation of the expressed receptors. Molecular Pharmacology. 33: 133-9. PMID 2828911 |
0.649 |
|
| 1987 |
Yoshimasa T, Sibley DR, Bouvier M, Lefkowitz RJ, Caron MG. Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation. Nature. 327: 67-70. PMID 3033513 DOI: 10.1038/327067A0 |
0.806 |
|
| 1987 |
Bouvier M, Leeb-Lundberg LM, Benovic JL, Caron MG, Lefkowitz RJ. Regulation of adrenergic receptor function by phosphorylation. II. Effects of agonist occupancy on phosphorylation of alpha 1- and beta 2-adrenergic receptors by protein kinase C and the cyclic AMP-dependent protein kinase. The Journal of Biological Chemistry. 262: 3106-13. PMID 3029101 |
0.78 |
|
| 1987 |
Dohlman HG, Bouvier M, Benovic JL, Caron MG, Lefkowitz RJ. The multiple membrane spanning topography of the beta 2-adrenergic receptor. Localization of the sites of binding, glycosylation, and regulatory phosphorylation by limited proteolysis. The Journal of Biological Chemistry. 262: 14282-8. PMID 2821000 |
0.743 |
|
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