Michael Pollak - Publications

Affiliations: 
McGill University, Montreal, QC, Canada 
Area:
Cell Biology

303 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Watts EL, Perez-Cornago A, Fensom GK, Smith-Byrne K, Noor U, Andrews CD, Gunter MJ, Holmes MV, Martin RM, Tsilidis KK, Albanes D, Barricarte A, Bueno-de-Mesquita HB, Cohn BA, Deschasaux-Tanguy M, ... ... Pollak MN, et al. Circulating insulin-like growth factors and risks of overall, aggressive and early-onset prostate cancer: a collaborative analysis of 20 prospective studies and Mendelian randomization analysis. International Journal of Epidemiology. PMID 35726641 DOI: 10.1093/ije/dyac124  0.336
2022 Ma C, Wang Y, Wilson KM, Mucci LA, Stampfer MJ, Pollak M, Penney KL. Circulating Insulin-Like Growth Factor 1-Related Biomarkers and Risk of Lethal Prostate Cancer. Jnci Cancer Spectrum. 6: pkab091. PMID 35047751 DOI: 10.1093/jncics/pkab091  0.339
2021 Rosendahl AH, Björner S, Ygland Rödström M, Jirström K, Borgquist S, Ingvar C, Pollak MN, Jernström H. Pre- and Postoperative Circulating IGF-I, IGFBP-3, and IGFBP-7 Levels in Relation to Endocrine Treatment and Breast Cancer Recurrence: A Nested Case-Control Study. Frontiers in Oncology. 11: 626058. PMID 33767994 DOI: 10.3389/fonc.2021.626058  0.33
2020 Gómez-Izquierdo J, Filion KB, Boivin JF, Azoulay L, Pollak M, Yu OHY. Subclinical hypothyroidism and the risk of cancer incidence and cancer mortality: a systematic review. Bmc Endocrine Disorders. 20: 83. PMID 32517676 DOI: 10.1186/S12902-020-00566-9  0.349
2020 Meyerhardt JA, Irwin ML, Jones LW, Zhang S, Campbell N, Brown JC, Pollak M, Sorrentino A, Cartmel B, Harrigan M, Tolaney SM, Winer E, Ng K, Abrams T, Fuchs CS, et al. Randomized Phase II Trial of Exercise, Metformin, or Both on Metabolic Biomarkers in Colorectal and Breast Cancer Survivors. Jnci Cancer Spectrum. 4: pkz096. PMID 32090192 DOI: 10.1093/Jncics/Pkz096  0.33
2019 Hada M, Oh H, Pfeiffer RM, Falk RT, Fan S, Mullooly M, Pollak M, Geller B, Vacek PM, Weaver D, Shepherd J, Wang J, Fan B, Mahmoudzadeh AP, Malkov S, et al. Relationship of circulating insulin-like growth factor-I and binding proteins 1-7 with mammographic density among women undergoing image-guided diagnostic breast biopsy. Breast Cancer Research : Bcr. 21: 81. PMID 31337427 DOI: 10.1186/S13058-019-1162-8  0.434
2019 Watts EL, Perez-Cornago A, Appleby PN, Albanes D, Ardanaz E, Black A, Bueno-de-Mesquita HB, Chan JM, Chen C, Chubb SAP, Cook MB, Deschasaux M, Donovan JL, English DR, Flicker L, ... ... Pollak M, et al. The associations of anthropometric, behavioural and sociodemographic factors with circulating concentrations of IGF-I, IGF-II, IGFBP-1, IGFBP-2, and IGFBP-3 in a pooled analysis of 16,024 men from 22 studies. International Journal of Cancer. PMID 30873591 DOI: 10.1002/Ijc.32276  0.408
2019 Heitzeneder S, Sotillo E, Shern JF, Sindiri S, Xu P, Jones R, Pollak M, Noer PR, Lorette J, Fazli L, Alag A, Meltzer P, Lau C, Conover CA, Oxvig C, et al. Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ewing Sarcoma: Role in Tumor Growth and Immune Evasion. Journal of the National Cancer Institute. PMID 30698726 DOI: 10.1093/Jnci/Djy209  0.317
2019 Mark M, Klingbiel D, Mey U, Winterhalder R, Rothermundt C, Gillessen S, von Moos R, Pollak M, Manetsch G, Strebel R, Cathomas R. Impact of Addition of Metformin to Abiraterone in Metastatic Castration-Resistant Prostate Cancer Patients With Disease Progressing While Receiving Abiraterone Treatment (MetAb-Pro): Phase 2 Pilot Study. Clinical Genitourinary Cancer. PMID 30686756 DOI: 10.1016/J.Clgc.2018.12.009  0.349
2019 Campbell PT, Newton C, Jacobs EJ, Pollak M, Gapstur SM. Abstract 594: Associations of hemoglobin A1c with risk of diabetes-related cancers in the Cancer Prevention Study-II Nutrition Cohort (CPS-II NC) Epidemiology. DOI: 10.1158/1538-7445.Sabcs18-594  0.335
2019 Guinter M, Gapstur S, Flanders WD, Wang Y, Rees-Punia E, McCullough M, Alcaraz KI, Pollak M, Campbell P. Abstract 596: Association between an empirically-derived inflammatory lifestyle score and incident colorectal cancer Cancer Research. 79: 596-596. DOI: 10.1158/1538-7445.Am2019-596  0.354
2019 Wang Y, Campbell PT, Stevens VL, Newton CC, Jacobs EJ, Pollak M, Gapstur SM. Abstract 2683: Biomarkers of glucose homeostasis and inflammation and risk of prostate cancer: A case-cohort study Cancer Research. 79: 2683-2683. DOI: 10.1158/1538-7445.Am2019-2683  0.371
2018 Lord SR, Cheng WC, Liu D, Gaude E, Haider S, Metcalf T, Patel N, Teoh EJ, Gleeson F, Bradley K, Wigfield S, Zois C, McGowan DR, Ah-See ML, Thompson AM, ... ... Pollak M, et al. Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer. Cell Metabolism. PMID 30244975 DOI: 10.1016/J.Cmet.2018.08.021  0.322
2018 Hulea L, Gravel SP, Morita M, Cargnello M, Uchenunu O, Im YK, Lehuédé C, Ma EH, Leibovitch M, McLaughlan S, Blouin MJ, Parisotto M, Papavasiliou V, Lavoie C, Larsson O, ... ... Pollak M, et al. Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides. Cell Metabolism. PMID 30244971 DOI: 10.1016/J.Cmet.2018.09.001  0.338
2018 Ahearn TU, Peisch S, Pettersson A, Ebot EM, Zhou K, Graff RE, Sinnott JA, Fazli L, Judson GL, Bismar TA, Rider JR, Gerke T, Chan JM, Fiorentino M, Flavin R, ... ... Pollak M, et al. Expression of IGF/insulin receptor in prostate cancer tissue and progression to lethal disease. Carcinogenesis. PMID 30165429 DOI: 10.1093/Carcin/Bgy112  0.437
2018 Pollak M. Diet boosts the effectiveness of a cancer drug. Nature. 560: 439-440. PMID 30127476 DOI: 10.1038/D41586-018-05871-X  0.402
2018 Im YK, Najyb O, Gravel SP, McGuirk S, Ahn R, Avizonis D, Chénard V, Sabourin V, Hudson J, Pawson T, Topisirovic I, Pollak MN, St-Pierre J, Ursini-Siegel J. Interplay between ShcA signaling and PGC-1α triggers targetable metabolic vulnerabilities in breast cancer. Cancer Research. PMID 29930100 DOI: 10.1158/0008-5472.Can-17-3696  0.337
2018 Tognon CE, Rafn B, Cetinbas NM, Kamura T, Trigo G, Rotblat B, Okumura F, Matsumoto M, Chow C, Davare M, Pollak M, Mayor T, Sorensen PH. Insulin-like growth factor 1 receptor stabilizes the ETV6-NTRK3 chimeric oncoprotein by blocking its KPC1/Rnf123-mediated proteasomal degradation. The Journal of Biological Chemistry. PMID 29903916 DOI: 10.1074/Jbc.Ra117.000321  0.391
2018 Oh H, Pfeiffer RM, Falk RT, Horne HN, Xiang J, Pollak M, Brinton LA, Storniolo AMV, Sherman ME, Gierach GL, Figueroa JD. Serum insulin-like growth factor-I and insulin-like growth factor binding protein-3 in relation to terminal duct lobular unit involution of the normal breast in Caucasian and African American women: the Susan G. Komen Tissue Bank. International Journal of Cancer. PMID 29473153 DOI: 10.1002/Ijc.31333  0.391
2018 Oh H, Pfeiffer RM, Falk RT, Horne HN, Xiang J, Pollak M, Brinton LA, Storniolo AMV, Sherman ME, Gierach GL, Figueroa JD. Abstract A36: Serum insulin-like growth factor (IGF)-I and IGF binding protein-3 in relation to terminal duct lobular unit involution in Caucasian and African American women: The Susan G. Komen Tissue Bank Cancer Epidemiology, Biomarkers & Prevention. 27. DOI: 10.1158/1538-7755.Disp17-A36  0.425
2018 Mahalingam D, Hanni S, Fountzilas C, Michalek J, Sarantopoulos J, Pillai SMA, Kuhn J, Pollak M, Thompson I. Abstract 3269: Metformin to prevent metabolic syndrome associated with androgen deprivation therapy (ADT): Metabolic analysis from a placebo-controlled study of metformin in non-diabetic men initiating ADT for advanced prostate cancer (PCa) Cancer Research. 78: 3269-3269. DOI: 10.1158/1538-7445.Am2018-3269  0.381
2017 Aneke-Nash CS, Xue X, Qi Q, Biggs ML, Cappola A, Kuller L, Pollak M, Psaty BM, Siscovick D, Mukamal K, Strickler HD, Kaplan RC. The Association between IGF-I and IGFBP-3 and Incident Diabetes in an Older Population of Men and Women in the Cardiovascular Health Study. The Journal of Clinical Endocrinology and Metabolism. PMID 29040592 DOI: 10.1210/Jc.2017-01273  0.371
2017 Wu JW, Azoulay L, Majdan A, Boivin JF, Pollak M, Suissa S. Long-Term Use of Long-Acting Insulin Analogs and Breast Cancer Incidence in Women With Type 2 Diabetes. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2017734491. PMID 28953430 DOI: 10.1200/Jco.2017.73.4491  0.4
2017 Toriola AT, Ziegler M, Li Y, Pollak M, Stolzenberg-Solomon R. Prediagnosis Circulating Insulin-Like Growth Factors and Pancreatic Cancer Survival. Annals of Surgical Oncology. PMID 28681154 DOI: 10.1245/S10434-017-5988-Y  0.43
2017 Gucalp A, Iyengar NM, Zhou XK, Giri DD, Falcone DJ, Wang H, Williams S, Krasne MD, Yaghnam I, Kunzel B, Morris PG, Jones LW, Pollak M, Laudone VP, Hudis CA, et al. Periprostatic adipose inflammation is associated with high-grade prostate cancer. Prostate Cancer and Prostatic Diseases. PMID 28653675 DOI: 10.1038/Pcan.2017.31  0.318
2017 Lin D, Ettinger SL, Qu S, Xue H, Nabavi N, Choi SYC, Bell RH, Mo F, Haegert AM, Gout PW, Fleshner N, Gleave ME, Pollak M, Collins CC, Wang Y. Metabolic heterogeneity signature of primary treatment-naïve prostate cancer. Oncotarget. 8: 25928-25941. PMID 28460430 DOI: 10.18632/Oncotarget.15237  0.355
2017 Miles FL, Goodman PJ, Tangen C, Torkko KC, Schenk JM, Song X, Pollak M, Thompson IM, Neuhouser ML. Interactions of the Insulin-Like Growth Factor Axis and Vitamin D in Prostate Cancer Risk in the Prostate Cancer Prevention Trial. Nutrients. 9. PMID 28417914 DOI: 10.3390/Nu9040378  0.414
2017 Brown KA, Iyengar NM, Zhou XK, Gucalp A, Subbaramaiah K, Wang H, Giri DD, Morrow M, Falcone DJ, Wendel NK, Winston LA, Pollak M, Dierickx A, Hudis CA, Dannenberg AJ. Menopause is a determinant of breast aromatase expression and its associations with BMI, inflammation and systemic markers. The Journal of Clinical Endocrinology and Metabolism. PMID 28323914 DOI: 10.1210/Jc.2016-3606  0.324
2017 Iyengar NM, Brown KA, Zhou XK, Gucalp A, Subbaramaiah K, Giri DD, Zahid H, Bhardwaj P, Wendel NK, Falcone DJ, Wang H, Williams S, Pollak M, Morrow M, Hudis CA, et al. Metabolic Obesity, Adipose Inflammation and Elevated Breast Aromatase in Women with Normal Body Mass Index. Cancer Prevention Research (Philadelphia, Pa.). PMID 28270386 DOI: 10.1158/1940-6207.Capr-16-0314  0.327
2017 Hulea L, Cargnello M, Gravel S, Im Y, McLaughlan S, Zhao Y, Ching J, Cai Y, Larsson O, Ohh M, Ursini-Siegel J, St-Pierre J, Pollak M, Topisirovic I. Abstract A31: eIF4F links translation to energy stress response in cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Transcontrol16-A31  0.367
2017 Iyengar N, Brown K, Zhou X, Subbaramaiah K, Giri D, Gucalp A, Howe L, Zahid H, Bhardwaj P, Wendel N, Falcone D, Morrow M, Wang H, Williams S, Pollak M, et al. Abstract PD5-05: Metabolic obesity, adipose inflammation and aromatase: Potential drivers of breast cancer risk in women with normal body mass index Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-Pd5-05  0.345
2017 Choi SY, Ettinger SL, Lin D, Xue H, Bell RH, Mo F, Pollak M, Collins CC, Wang Y. Abstract 4420: Elevated glycolytic gene signature in patient-derived neuroendocrine prostate cancer xenograft models and its clinical relevance Cancer Research. 77: 4420-4420. DOI: 10.1158/1538-7445.Am2017-4420  0.335
2016 Murphy N, Falk RT, Messinger DB, Pollak M, Xue X, Lin J, Sgueglia R, Strickler HD, Gaudet MM, Gunter MJ. Influence of Fasting Status and Sample Preparation on Metabolic Biomarker Measurements in Postmenopausal Women. Plos One. 11: e0167832. PMID 27930694 DOI: 10.1371/Journal.Pone.0167832  0.381
2016 Kaplan RC, Strizich G, Aneke-Nash C, Dominguez-Islas C, Bůžková P, Strickler H, Rohan T, Pollak M, Kuller L, Kizer JR, Cappola A, Li CI, Psaty BM, Newman A. Insulinlike growth factor binding protein-1 and ghrelin predict health outcomes among older adults: CHS cohort. The Journal of Clinical Endocrinology and Metabolism. jc20162779. PMID 27820656 DOI: 10.1210/Jc.2016-2779  0.313
2016 Gusscott S, Jenkins CE, Lam SH, Giambra V, Pollak M, Weng AP. IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias. Plos One. 11: e0161158. PMID 27532210 DOI: 10.1371/Journal.Pone.0161158  0.361
2016 Hayes BD, Brady L, Pollak MN, Finn S. Exercise and prostate cancer: evidence and proposed mechanisms for disease modification. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 27389872 DOI: 10.1158/1055-9965.Epi-16-0223  0.363
2016 Teumer A, Qi Q, Nethander M, Aschard H, Bandinelli S, Beekman M, Berndt SI, Bidlingmaier M, Broer L, Cappola A, Ceda GP, Chanock S, Chen MH, Chen TC, ... ... Pollak MN, et al. Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. Aging Cell. PMID 27329260 DOI: 10.1111/Acel.12490  0.614
2016 Yancu D, Blouin MJ, Birman E, Florianova L, Aleynikova O, Zakikhani M, VanderMeulen H, Seidman E, Pollak M. Insulin-like growth factor-3 knockout mice are resistant to experimental dextran sulfate sodium colitis. Journal of Gastroenterology and Hepatology. PMID 27253188 DOI: 10.1111/Jgh.13461  0.379
2016 Liu Z, Yokoyama NN, Blair CA, Li X, Avizonis D, Wu XR, Uchio E, Youssef R, McClelland M, Pollak M, Zi X. High Sensitivity of an Ha-RAS Transgenic Model of Superficial Bladder Cancer to Metformin Is Associated with ∼240-Fold Higher Drug Concentration in Urine than Serum. Molecular Cancer Therapeutics. PMID 26921394 DOI: 10.1158/1535-7163.Mct-15-0714-T  0.376
2016 Travis RC, Appleby PN, Martin RM, Holly JM, Albanes D, Black A, Bueno-de-Mesquita HB, Chan JM, Chen C, Chirlaque MD, Cook MB, Deschasaux M, Donovan JL, Ferrucci L, Galan P, ... ... Pollak MN, et al. A Meta-analysis of Individual Participant Data Reveals an Association between Circulating Levels of IGF-I and Prostate Cancer Risk. Cancer Research. 76: 2288-300. PMID 26921328 DOI: 10.1158/0008-5472.Can-15-1551  0.43
2016 Horne HN, Sherman ME, Pfeiffer RM, Figueroa JD, Khodr ZG, Falk RT, Pollak M, Patel DA, Palakal MM, Linville L, Papathomas D, Geller B, Vacek PM, Weaver DL, Chicoine R, et al. Circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3 and terminal duct lobular unit involution of the breast: a cross-sectional study of women with benign breast disease. Breast Cancer Research : Bcr. 18: 24. PMID 26893016 DOI: 10.1186/S13058-016-0678-4  0.404
2016 Aneke-Nash CS, Dominguez-Islas C, Bůžková P, Qi Q, Xue X, Pollak M, Strickler HD, Kaplan RC. Agreement between circulating IGF-I, IGFBP-1 and IGFBP-3 levels measured by current assays versus unavailable assays previously used in epidemiological studies. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 26: 11-6. PMID 26774400 DOI: 10.1016/J.Ghir.2015.12.007  0.355
2016 Sgroi DC, Chapman JA, Badovinac-Crnjevic T, Zarella E, Binns S, Zhang Y, Schnabel CA, Erlander MG, Pritchard KI, Han L, Shepherd LE, Goss PE, Pollak M. Assessment of the prognostic and predictive utility of the Breast Cancer Index (BCI): an NCIC CTG MA.14 study. Breast Cancer Research : Bcr. 18: 1. PMID 26728744 DOI: 10.1186/S13058-015-0660-6  0.362
2015 Iyengar NM, Zhou XK, Gucalp A, Morris PG, Howe LR, Giri D, Morrow M, Wang H, Pollak M, Jones LW, Hudis CA, Dannenberg AJ. Systemic Correlates of White Adipose Tissue Inflammation in Early-Stage Breast Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26712688 DOI: 10.1158/1078-0432.Ccr-15-2239  0.375
2015 Azoulay L, Eberg M, Benayoun S, Pollak M. 5α-Reductase Inhibitors and the Risk of Cancer-Related Mortality in Men With Prostate Cancer. Jama Oncology. 1: 314-20. PMID 26181177 DOI: 10.1001/Jamaoncol.2015.0387  0.353
2015 Catsburg C, Gunter MJ, Tinker L, Chlebowski RT, Pollak M, Strickler HD, Cote ML, Page DL, Rohan TE. Serum IGFBP-2 and Risk of Atypical Hyperplasia of the Breast. Journal of Cancer Epidemiology. 2015: 203284. PMID 26106415 DOI: 10.1155/2015/203284  0.363
2015 Stolzenberg-Solomon RZ, Newton CC, Silverman DT, Pollak M, Nogueira LM, Weinstein SJ, Albanes D, Männistö S, Jacobs EJ. Circulating Leptin and Risk of Pancreatic Cancer: A Pooled Analysis From 3 Cohorts. American Journal of Epidemiology. PMID 26085045 DOI: 10.1093/Aje/Kwv041  0.41
2015 Joerger M, van Schaik RH, Becker ML, Hayoz S, Pollak M, Cathomas R, Winterhalder R, Gillessen S, Rothermundt C. Multidrug and toxin extrusion 1 and human organic cation transporter 1 polymorphisms in patients with castration-resistant prostate cancer receiving metformin (SAKK 08/09). Prostate Cancer and Prostatic Diseases. 18: 167-72. PMID 25753371 DOI: 10.1038/Pcan.2015.8  0.318
2015 Blouin MJ, Bazile M, Birman E, Zakikhani M, Florianova L, Aleynikova O, Powell DR, Pollak M. Germ line knockout of IGFBP-3 reveals influences of the gene on mammary gland neoplasia. Breast Cancer Research and Treatment. 149: 577-85. PMID 25614235 DOI: 10.1007/S10549-015-3268-8  0.376
2015 Cao Y, Nimptsch K, Shui IM, Platz EA, Wu K, Pollak MN, Kenfield SA, Stampfer MJ, Giovannucci EL. Prediagnostic plasma IGFBP-1, IGF-1 and risk of prostate cancer. International Journal of Cancer. Journal International Du Cancer. 136: 2418-26. PMID 25348852 DOI: 10.1002/Ijc.29295  0.323
2015 Zell JA, McLaren CE, Morgan TR, Lawson MJ, Rezk S, Albers GC, Chen W, Carmichael JC, Rodriguez L, Szabo E, Ford L, Pollak M, Meyskens FL. Abstract A21: A Phase IIa trial of metformin for colorectal cancer risk reduction among patients with a history of colorectal adenomas and elevated body mass index Cancer Prevention Research. 8. DOI: 10.1158/1940-6215.Prev-14-A21  0.331
2015 Iyengar NM, Gucalp A, Zhou XK, Howe LR, Morris PG, Giri D, Subbaramaiah K, Bhardwaj P, Park SS, Pollak M, Morrow M, Hudis CA, Dannenberg AJ. Abstract P4-04-12: Both metabolic syndrome and statin use are more common in women with breast inflammation Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P4-04-12  0.364
2014 Gravel SP, Hulea L, Toban N, Birman E, Blouin MJ, Zakikhani M, Zhao Y, Topisirovic I, St-Pierre J, Pollak M. Serine deprivation enhances antineoplastic activity of biguanides. Cancer Research. 74: 7521-33. PMID 25377470 DOI: 10.1158/0008-5472.Can-14-2643-T  0.334
2014 Paxton RJ, Jung SY, Vitolins MZ, Fenton J, Paskett E, Pollak M, Hays-Grudo J, Hursting SD, Chang S. Associations between time spent sitting and cancer-related biomarkers in postmenopausal women: an exploration of effect modifiers. Cancer Causes & Control : Ccc. 25: 1427-37. PMID 25238978 DOI: 10.1007/S10552-014-0434-Y  0.366
2014 Laskov I, Drudi L, Beauchamp MC, Yasmeen A, Ferenczy A, Pollak M, Gotlieb WH. Anti-diabetic doses of metformin decrease proliferation markers in tumors of patients with endometrial cancer. Gynecologic Oncology. 134: 607-14. PMID 24972190 DOI: 10.1016/J.Ygyno.2014.06.014  0.369
2014 Jacobs EJ, Newton CC, Silverman DT, Nogueira LM, Albanes D, Männistö S, Pollak M, Stolzenberg-Solomon RZ. Serum transforming growth factor-β1 and risk of pancreatic cancer in three prospective cohort studies. Cancer Causes & Control : Ccc. 25: 1083-91. PMID 24913781 DOI: 10.1007/S10552-014-0409-Z  0.337
2014 Beasley JM, Wedick NM, Rajpathak SN, Xue X, Holmes MD, Gunter MJ, Wylie-Rosett J, Rohan TE, Pollak M, Kaplan RC, Hu FB, Sun Q, Strickler HD. Circulating IGF-axis protein levels and their relation with levels of plasma adipocytokines and macronutrient consumption in women. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 24: 142-9. PMID 24888819 DOI: 10.1016/J.Ghir.2014.04.006  0.357
2014 Joshua AM, Zannella VE, Downes MR, Bowes B, Hersey K, Koritzinsky M, Schwab M, Hofmann U, Evans A, van der Kwast T, Trachtenberg J, Finelli A, Fleshner N, Sweet J, Pollak M. A pilot 'window of opportunity' neoadjuvant study of metformin in localised prostate cancer. Prostate Cancer and Prostatic Diseases. 17: 252-8. PMID 24861559 DOI: 10.1038/Pcan.2014.20  0.395
2014 Cao Y, Lindström S, Schumacher F, Stevens VL, Albanes D, Berndt S, Boeing H, Bueno-de-Mesquita HB, Canzian F, Chamosa S, Chanock SJ, Diver WR, Gapstur SM, Gaziano JM, Giovannucci EL, ... ... Pollak M, et al. Insulin-like growth factor pathway genetic polymorphisms, circulating IGF1 and IGFBP3, and prostate cancer survival. Journal of the National Cancer Institute. 106: dju085. PMID 24824313 DOI: 10.1093/Jnci/Dju218  0.437
2014 Takeuchi A, Shiota M, Beraldi E, Thaper D, Takahara K, Ibuki N, Pollak M, Cox ME, Naito S, Gleave ME, Zoubeidi A. Insulin-like growth factor-I induces CLU expression through Twist1 to promote prostate cancer growth. Molecular and Cellular Endocrinology. 384: 117-25. PMID 24491388 DOI: 10.1016/J.Mce.2014.01.012  0.425
2014 Mireuta M, Birman E, Barmash M, Pollak M. Quantification of binding of IGF-1 to BI 836845, a candidate therapeutic antibody against IGF-1 and IGF-2, and effects of this antibody on IGF-1:IGFBP-3 complexes in vitro and in male C57BL/6 mice. Endocrinology. 155: 703-15. PMID 24424057 DOI: 10.1210/En.2013-1791  0.353
2014 Rothermundt C, Hayoz S, Templeton AJ, Winterhalder R, Strebel RT, Bärtschi D, Pollak M, Lui L, Endt K, Schiess R, Rüschoff JH, Cathomas R, Gillessen S. Metformin in chemotherapy-naive castration-resistant prostate cancer: a multicenter phase 2 trial (SAKK 08/09). European Urology. 66: 468-74. PMID 24412228 DOI: 10.1016/J.Eururo.2013.12.057  0.337
2014 Grimaldi-Bensouda L, Cameron D, Marty M, Barnett AH, Penault-Llorca F, Pollak M, Charbonnel B, Riddle M, Mignot L, Boivin JF, Khachatryan A, Rossignol M, Bénichou J, Alpérovitch A, Abenhaim L, et al. Risk of breast cancer by individual insulin use: an international multicenter study. Diabetes Care. 37: 134-43. PMID 23949559 DOI: 10.2337/Dc13-0695  0.409
2014 Pollak M. Energy balance at the organism and cellular level: effects of biguanides Cancer & Metabolism. 2. DOI: 10.1186/2049-3002-2-S1-O26  0.385
2013 Muhlbradt E, Ma J, Severi G, Ortner E, Hayes V, Hoang HN, Stampfer M, Giles G, Pollak M, Gelmann EP. Variant NKX3.1 and Serum IGF-1: Investigation of Interaction in Prostate Cancer. Genes & Cancer. 4: 535-45. PMID 24386513 DOI: 10.1177/1947601913506009  0.384
2013 Pettersson A, Lis RT, Meisner A, Flavin R, Stack EC, Fiorentino M, Finn S, Graff RE, Penney KL, Rider JR, Nuttall EJ, Martin NE, Sesso HD, Pollak M, Stampfer MJ, et al. Modification of the association between obesity and lethal prostate cancer by TMPRSS2:ERG. Journal of the National Cancer Institute. 105: 1881-90. PMID 24292212 DOI: 10.1093/Jnci/Djt332  0.409
2013 Van Dang C, Pollak M. Why Cancer & Metabolism? Why now? Cancer & Metabolism. 1: 1. PMID 24280107 DOI: 10.1186/2049-3002-1-1  0.352
2013 Hvid H, Blouin MJ, Birman E, Damgaard J, Poulsen F, Fels JJ, Fledelius C, Hansen BF, Pollak M. Treatment with insulin analog X10 and IGF-1 increases growth of colon cancer allografts. Plos One. 8: e79710. PMID 24260289 DOI: 10.1371/Journal.Pone.0079710  0.421
2013 Pollak M. Potential applications for biguanides in oncology. The Journal of Clinical Investigation. 123: 3693-700. PMID 23999444 DOI: 10.1172/Jci67232  0.301
2013 Zu K, Martin NE, Fiorentino M, Flavin R, Lis RT, Sinnott JA, Finn S, Penney KL, Ma J, Fazli L, Gleave ME, Bismar TA, Stampfer MJ, Pollak MN, Loda M, et al. Protein expression of PTEN, insulin-like growth factor I receptor (IGF-IR), and lethal prostate cancer: a prospective study. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 22: 1984-93. PMID 23983239 DOI: 10.1158/1055-9965.Epi-13-0349  0.322
2013 Takahara K, Ibuki N, Ghaffari M, Tearle H, Ong CJ, Azuma H, Gleave ME, Pollak M, Cox ME. The influence of growth hormone/insulin-like growth factor deficiency on prostatic dysplasia in pbARR2-Cre, PTEN knockout mice Prostate Cancer and Prostatic Diseases. 16: 239-247. PMID 23689346 DOI: 10.1038/Pcan.2013.14  0.39
2013 Palumbo MO, Kavan P, Miller WH, Panasci L, Assouline S, Johnson N, Cohen V, Patenaude F, Pollak M, Jagoe RT, Batist G. Systemic cancer therapy: achievements and challenges that lie ahead. Frontiers in Pharmacology. 4: 57. PMID 23675348 DOI: 10.3389/Fphar.2013.00057  0.322
2013 Lubik AA, Gunter JH, Hollier BG, Ettinger S, Fazli L, Stylianou N, Hendy SC, Adomat HH, Gleave ME, Pollak M, Herington A, Nelson CC. IGF2 increases de novo steroidogenesis in prostate cancer cells. Endocrine-Related Cancer. 20: 173-86. PMID 23319492 DOI: 10.1530/Erc-12-0250  0.42
2013 Neuhouser ML, Platz EA, Till C, Tangen CM, Goodman PJ, Kristal A, Parnes HL, Tao Y, Figg WD, Lucia MS, Hoque A, Hsing AW, Thompson IM, Pollak M. Insulin-like growth factors and insulin-like growth factor-binding proteins and prostate cancer risk: results from the prostate cancer prevention trial. Cancer Prevention Research (Philadelphia, Pa.). 6: 91-9. PMID 23315596 DOI: 10.1158/1940-6207.Capr-12-0250  0.44
2013 Song Y, Chavarro JE, Cao Y, Qiu W, Mucci L, Sesso HD, Stampfer MJ, Giovannucci E, Pollak M, Liu S, Ma J. Whole milk intake is associated with prostate cancer-specific mortality among U.S. male physicians. The Journal of Nutrition. 143: 189-96. PMID 23256145 DOI: 10.3945/Jn.112.168484  0.316
2013 Dallal CM, Brinton LA, Bauer DC, Buist DS, Cauley JA, Hue TF, Lacroix A, Tice JA, Chia VM, Falk R, Pfeiffer R, Pollak M, Veenstra TD, Xu X, Lacey JV, et al. Obesity-related hormones and endometrial cancer among postmenopausal women: a nested case-control study within the B~FIT cohort. Endocrine-Related Cancer. 20: 151-60. PMID 23222000 DOI: 10.1530/Erc-12-0229  0.373
2013 Liao LM, Weinstein SJ, Pollak M, Li Z, Virtamo J, Albanes D, Chow WH, Purdue MP. Prediagnostic circulating adipokine concentrations and risk of renal cell carcinoma in male smokers. Carcinogenesis. 34: 109-12. PMID 23042303 DOI: 10.1093/Carcin/Bgs322  0.33
2013 Jung SY, Hays-Grudo J, Paskett E, Hursting SD, Fenton J, Pollak M, Vitolins M, Chang S. Abstract PR04: Exogenous estrogen as a mediator of racial differences in insulin-like growth factor-I levels among postmenopausal women Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-Pr04  0.35
2013 Jung SY, Paxton RJ, Hays-Grudo J, Paskett E, Hursting SD, Fenton J, Pollak M, Vitolins M, Chang S. Abstract A35: Associations between time spent sitting and cancer-related biomarkers: An exploration of effect modifiers Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-A35  0.359
2012 Evdokimova V, Tognon CE, Benatar T, Yang W, Krutikov K, Pollak M, Sorensen PH, Seth A. IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors. Science Signaling. 5: ra92. PMID 23250396 DOI: 10.1126/Scisignal.2003184  0.412
2012 Birmann BM, Neuhouser ML, Rosner B, Albanes D, Buring JE, Giles GG, Lan Q, Lee IM, Purdue MP, Rothman N, Severi G, Yuan JM, Anderson KC, Pollak M, Rifai N, et al. Prediagnosis biomarkers of insulin-like growth factor-1, insulin, and interleukin-6 dysregulation and multiple myeloma risk in the Multiple Myeloma Cohort Consortium. Blood. 120: 4929-37. PMID 23074271 DOI: 10.1182/Blood-2012-03-417253  0.354
2012 Colquhoun AJ, Venier NA, Vandersluis AD, Besla R, Sugar LM, Kiss A, Fleshner NE, Pollak M, Klotz LH, Venkateswaran V. Metformin enhances the antiproliferative and apoptotic effect of bicalutamide in prostate cancer. Prostate Cancer and Prostatic Diseases. 15: 346-52. PMID 22614062 DOI: 10.1038/Pcan.2012.16  0.348
2012 Jenkins CR, Shevchuk OO, Giambra V, Lam SH, Carboni JM, Gottardis MM, Holzenberger M, Pollak M, Humphries RK, Weng AP. IGF signaling contributes to malignant transformation of hematopoietic progenitors by the MLL-AF9 oncoprotein. Experimental Hematology. 40: 715-723.e6. PMID 22613471 DOI: 10.1016/J.Exphem.2012.05.003  0.339
2012 Larsson O, Morita M, Topisirovic I, Alain T, Blouin MJ, Pollak M, Sonenberg N. Distinct perturbation of the translatome by the antidiabetic drug metformin. Proceedings of the National Academy of Sciences of the United States of America. 109: 8977-82. PMID 22611195 DOI: 10.1073/Pnas.1201689109  0.328
2012 Jones LW, Antonelli J, Masko EM, Broadwater G, Lascola CD, Fels D, Dewhirst MW, Dyck JR, Nagendran J, Flores CT, Betof AS, Nelson ER, Pollak M, Dash RC, Young ME, et al. Exercise modulation of the host-tumor interaction in an orthotopic model of murine prostate cancer. Journal of Applied Physiology (Bethesda, Md. : 1985). 113: 263-72. PMID 22604887 DOI: 10.1152/Japplphysiol.01575.2011  0.307
2012 Rajpathak SN, He M, Sun Q, Kaplan RC, Muzumdar R, Rohan TE, Gunter MJ, Pollak M, Kim M, Pessin JE, Beasley J, Wylie-Rosett J, Hu FB, Strickler HD. Insulin-like growth factor axis and risk of type 2 diabetes in women. Diabetes. 61: 2248-54. PMID 22554827 DOI: 10.2337/Db11-1488  0.328
2012 Chi KN, Gleave ME, Fazli L, Goldenberg SL, So A, Kollmannsberger C, Murray N, Tinker A, Pollak M. A phase II pharmacodynamic study of preoperative figitumumab in patients with localized prostate cancer Clinical Cancer Research. 18: 3407-3413. PMID 22553344 DOI: 10.1158/1078-0432.CCR-12-0482  0.303
2012 Gunter JH, Lubik AA, McKenzie I, Pollak M, Nelson CC. The Interactions between Insulin and Androgens in Progression to Castrate-Resistant Prostate Cancer. Advances in Urology. 2012: 248607. PMID 22548055 DOI: 10.1155/2012/248607  0.412
2012 Pollak M. Metformin and pancreatic cancer: a clue requiring investigation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 2723-5. PMID 22465829 DOI: 10.1158/1078-0432.Ccr-12-0694  0.353
2012 Faupel-Badger JM, Wang Y, Staff AC, Karumanchi SA, Stanczyk FZ, Pollak M, Hoover RN, Troisi R. Maternal and Cord Steroid Sex Hormones, Angiogenic Factors and Insulin-like Growth Factor Axis in African-American Preeclamptic and Uncomplicated Pregnancies Cancer Causes & Control. 23: 779-784. PMID 22418778 DOI: 10.1007/S10552-012-9934-9  0.313
2012 Ollberding NJ, Cheng I, Wilkens LR, Henderson BE, Pollak MN, Kolonel LN, Le Marchand L. Genetic variants, prediagnostic circulating levels of insulin-like growth factors, insulin, and glucose and the risk of colorectal cancer: the Multiethnic Cohort study. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 21: 810-20. PMID 22354904 DOI: 10.1158/1055-9965.Epi-11-1105  0.304
2012 Pollak M. The insulin and insulin-like growth factor receptor family in neoplasia: an update Nature Reviews Cancer. 12: 159-169. PMID 22337149 DOI: 10.1038/Nrc3215  0.401
2012 Pollak M. The insulin receptor/insulin-like growth factor receptor family as a therapeutic target in oncology. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 40-50. PMID 22215905 DOI: 10.1158/1078-0432.Ccr-11-0998  0.355
2012 Gao Y, Katki H, Graubard B, Pollak M, Martin M, Tao Y, Schoen RE, Church T, Hayes RB, Greene MH, Berndt SI. Serum IGF1, IGF2 and IGFBP3 and risk of advanced colorectal adenoma. International Journal of Cancer. Journal International Du Cancer. 131: E105-13. PMID 21932422 DOI: 10.1002/Ijc.26438  0.391
2012 Yerushalmi R, Gelmon KA, Leung S, Gao D, Cheang M, Pollak M, Turashvili G, Gilks BC, Kennecke H. Insulin-like growth factor receptor (IGF-1R) in breast cancer subtypes. Breast Cancer Research and Treatment. 132: 131-42. PMID 21574055 DOI: 10.1007/S10549-011-1529-8  0.394
2012 Pollak M. Energy balance and cancer risk at the cellular and whole organism level: modification by metformin Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S3-O21  0.399
2012 Joshua AM, Zannella V, Bowes B, Koritzinsky M, Sweet J, Evans A, Trachtenberg J, Jewett M, Finelli A, Fleshner N, Pollak M. Abstract CT-04: A phase II study of neoadjuvant metformin in prostatic carcinoma Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Ct-04  0.391
2012 Ma J, Giovannucci E, Nguyen PL, Qiu W, Chavarro J, Rosner B, Cook NR, Platz EA, Gaziano JM, Pollak M, Stampfer MJ. Abstract 4501: Energetic risk and prostate cancer-specific and all-cause mortality in two large cohorts of men with localized prostate cancer Cancer Research. 72: 4501-4501. DOI: 10.1158/1538-7445.Am2012-4501  0.317
2012 Lubik A, Gunter J, Ettinger S, Fazil L, Stylianou N, Hendy S, Adomat H, Hollier B, Gleave M, Pollak M, Herington A, Nelson C. P03-26 Insulin-like Growth Factor-II increases de novo steroidogenesis in prostate cancer cells Growth Hormone & Igf Research. 22: S80. DOI: 10.1016/S1096-6374(12)60211-1  0.431
2012 Blouin M, Zhao Y, Birman E, Pollak M. 636 Elevated Insulin Can Reduce Effectiveness of PI3K Inhibitors –Rationale for Co-targeting the Insulin Receptor Family and PI3K European Journal of Cancer. 48: S151. DOI: 10.1016/S0959-8049(12)71284-4  0.338
2012 Rothermundt CA, Cathomas R, Templeton A, Winterhalder RC, Strebel R, Baertschi D, Pollak M, Lui L, Crowe S, Gillessen S. Metformin in Chemotherapy-Naïve Castration Resistant Prostate Cancer (CRPC): A Multicenter Phase II Trial (SAKK 08/09) Annals of Oncology. 23. DOI: 10.1016/S0923-7534(20)33475-X  0.406
2011 Segal ED, Yasmeen A, Beauchamp MC, Rosenblatt J, Pollak M, Gotlieb WH. Relevance of the OCT1 transporter to the antineoplastic effect of biguanides. Biochemical and Biophysical Research Communications. 414: 694-9. PMID 21986525 DOI: 10.1016/J.Bbrc.2011.09.134  0.303
2011 Dhillon PK, Penney KL, Schumacher F, Rider JR, Sesso HD, Pollak M, Fiorentino M, Finn S, Loda M, Rifai N, Mucci LA, Giovannucci E, Stampfer MJ, Ma J. Common polymorphisms in the adiponectin and its receptor genes, adiponectin levels and the risk of prostate cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 20: 2618-27. PMID 21960694 DOI: 10.1158/1055-9965.Epi-11-0434  0.386
2011 Faupel-Badger JM, Wang Y, Karumanchi SA, Stanczyk F, Pollak M, McElrath T, Hoover RN, Troisi R. Associations of pregnancy characteristics with maternal and cord steroid hormones, angiogenic factors, and insulin-like growth factor axis. Cancer Causes & Control. 22: 1587-1595. PMID 21947778 DOI: 10.1007/S10552-011-9835-3  0.341
2011 Dool CJ, Mashhedi H, Zakikhani M, David S, Zhao Y, Birman E, Carboni JM, Gottardis M, Blouin MJ, Pollak M. IGF1/insulin receptor kinase inhibition by BMS-536924 is better tolerated than alloxan-induced hypoinsulinemia and more effective than metformin in the treatment of experimental insulin-responsive breast cancer. Endocrine-Related Cancer. 18: 699-709. PMID 21946410 DOI: 10.1530/Erc-11-0136  0.43
2011 Pritchard KI, Shepherd LE, Chapman JA, Norris BD, Cantin J, Goss PE, Dent SF, Walde D, Vandenberg TA, Findlay B, O'Reilly SE, Wilson CF, Han L, Piura E, Whelan TJ, ... Pollak MN, et al. Randomized trial of tamoxifen versus combined tamoxifen and octreotide LAR Therapy in the adjuvant treatment of early-stage breast cancer in postmenopausal women: NCIC CTG MA.14. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 3869-76. PMID 21911723 DOI: 10.1200/JCO.2010.33.7006  0.334
2011 Zhang X, Giovannucci EL, Smith-Warner SA, Wu K, Fuchs CS, Pollak M, Willett WC, Ma J. A prospective study of intakes of zinc and heme iron and colorectal cancer risk in men and women. Cancer Causes & Control : Ccc. 22: 1627-37. PMID 21909950 DOI: 10.1007/S10552-011-9839-Z  0.338
2011 Mashhedi H, Blouin MJ, Zakikhani M, David S, Zhao Y, Bazile M, Birman E, Algire C, Aliaga A, Bedell BJ, Pollak M. Metformin abolishes increased tumor (18)F-2-fluoro-2-deoxy-D-glucose uptake associated with a high energy diet. Cell Cycle (Georgetown, Tex.). 10: 2770-8. PMID 21811094 DOI: 10.4161/Cc.10.16.16219  0.342
2011 Medyouf H, Gusscott S, Wang H, Tseng JC, Wai C, Nemirovsky O, Trumpp A, Pflumio F, Carboni J, Gottardis M, Pollak M, Kung AL, Aster JC, Holzenberger M, Weng AP. High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling. The Journal of Experimental Medicine. 208: 1809-22. PMID 21807868 DOI: 10.1084/Jem.20110121  0.308
2011 Lubik AA, Gunter JH, Hendy SC, Locke JA, Adomat HH, Thompson V, Herington A, Gleave ME, Pollak M, Nelson CC. Insulin increases de novo steroidogenesis in prostate cancer cells. Cancer Research. 71: 5754-64. PMID 21747118 DOI: 10.1158/0008-5472.Can-10-2470  0.43
2011 Suissa S, Azoulay L, Dell’Aniello S, Evans M, Vora J, Pollak M. Long-term effects of insulin glargine on the risk of breast cancer Diabetologia. 54: 2254-2262. PMID 21614572 DOI: 10.1007/S00125-011-2190-9  0.399
2011 Mireuta M, Hancock MA, Pollak M. Binding between insulin-like growth factor 1 and insulin-like growth factor-binding protein 3 is not influenced by glucose or 2-deoxy-D-glucose. The Journal of Biological Chemistry. 286: 16567-73. PMID 21388950 DOI: 10.1074/Jbc.M110.213033  0.385
2011 Yasmeen A, Beauchamp MC, Piura E, Segal E, Pollak M, Gotlieb WH. Induction of apoptosis by metformin in epithelial ovarian cancer: involvement of the Bcl-2 family proteins. Gynecologic Oncology. 121: 492-8. PMID 21388661 DOI: 10.1016/J.Ygyno.2011.02.021  0.321
2011 Tognon CE, Somasiri AM, Evdokimova VE, Trigo G, Uy EE, Melnyk N, Carboni JM, Gottardis MM, Roskelley CD, Pollak M, Sorensen PH. ETV6-NTRK3-mediated breast epithelial cell transformation is blocked by targeting the IGF1R signaling pathway. Cancer Research. 71: 1060-70. PMID 21148487 DOI: 10.1158/0008-5472.Can-10-3096  0.421
2011 Algire C, Amrein L, Bazile M, David S, Zakikhani M, Pollak M. Diet and tumor LKB1 expression interact to determine sensitivity to anti-neoplastic effects of metformin in vivo. Oncogene. 30: 1174-1182. PMID 21102522 DOI: 10.1038/Onc.2010.483  0.35
2011 Takahara K, Tearle H, Ghaffari M, Gleave ME, Pollak M, Cox ME. Human prostate cancer xenografts in lit/lit mice exhibit reduced growth and androgen-independent progression Prostate. 71: 525-537. PMID 20878948 DOI: 10.1002/Pros.21268  0.407
2011 Nimptsch K, Platz EA, Pollak MN, Kenfield SA, Stampfer MJ, Willett WC, Giovannucci E. Plasma insulin-like growth factor 1 is positively associated with low-grade prostate cancer in the Health Professionals Follow-up Study 1993-2004. International Journal of Cancer. Journal International Du Cancer. 128: 660-7. PMID 20473871 DOI: 10.1002/Ijc.25381  0.31
2011 Ibuki N, Takahara K, Tearle H, Gleave ME, Ong CJ, Pollak M, Cox ME. Abstract 1096: Prostate tumor growth in pbARR2-Cre PTEN knockout mice is delayed in GH/IGF-I deficient mice Cancer Research. 71: 1096-1096. DOI: 10.1158/1538-7445.Am2011-1096  0.399
2011 Dong B, Chapman J, Yerushalmi R, Goss P, Pollak M, Burnell M, Bramwell V, Levine M, Pritchard K, Whelan T, Ingle J, Parulekar W, Shepherd L, Gelmon K. P5-14-01: Differences in Efficacy by Assessment Method: NCIC CTG Adjuvant Breast Cancer Trials MA.5, MA.12, MA.14, MA.21, MA.27 Meta-Analysis. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P5-14-01  0.308
2011 Bramwell V, Tuck A, Chapman J, Anborgh P, Postenka C, Shepherd L, Pritchard K, Han L, Wilson C, Pollak M, Chambers A. P2-12-28: Studies of a Malignancy-Associated Protein, Osteopontin, in NCIC CTG MA.14, a Randomized Trial of Tamoxifen Versus Combined Tamoxifen and Octreotide LAR in Adjuvant Treatment of Women with Early Breast Cancer. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P2-12-28  0.306
2011 Pollak M. MS3-3: Energy Metabolism in Breast Cancer: Translational Science Insights Relevant to Effects of Diet, Exercise, and Metformin on Risk and Prognosis. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-Ms3-3  0.448
2011 Colquhoun AJ, Venier NA, Vandersluis AD, Besla R, Fleshner NE, Pollak M, Klotz LH, Venkateswaran V. 936 Utilising Metformin As A Radiosensitising Agent In The Treatment Of Prostate Cancer European Urology Supplements. 10: 293. DOI: 10.1016/S1569-9056(11)60918-4  0.335
2011 Inoue T, Zakikhani M, Mireuta M, Blouin M, Pollak M. 420 In Vivo Castration-Resistant Acceleration Of Prostate Cancer Inhibited By A Small Molecule Inhibitor Of Insulin-Like Growth Factor 1 Receptor/Insulin Receptor Tyrosine Kinase The Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.509  0.384
2011 Takahara K, Ibuki N, Tearle H, Azuma H, Katsuoka Y, Gleave ME, Ong CJ, Pollak M, Cox ME. 740 Prostate Tumor Growth In Pbarr2-Cre Pten Knockout Mice Is Delayed In Gh/Igf-I Deficient Mice The Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.1709  0.302
2011 Colquhoun A, Venier N, Vandersluis A, Fleshner N, Pollak M, Klotz L, Venkateswaran V. 737 Utilizing Metformin As A Radiosensitizing Agent In The Treatment Of Prostate Cancer The Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.1706  0.334
2010 Schairer C, McCarty CA, Isaacs C, Sue LY, Pollak MN, Berg CD, Ziegler RG. Circulating insulin-like growth factor (IGF)-I and IGF binding protein (IGFBP)-3 levels and postmenopausal breast cancer risk in the prostate, lung, colorectal, and ovarian cancer screening trial (PLCO) cohort. Hormones & Cancer. 1: 100-11. PMID 21761353 DOI: 10.1007/s12672-010-0013-y  0.356
2010 Bordeleau L, Lipscombe L, Lubinski J, Ghadirian P, Foulkes WD, Neuhausen S, Ainsworth P, Pollak M, Sun P, Narod SA. Diabetes and breast cancer among women with BRCA1 and BRCA2 mutations. Cancer. 117: 1812-8. PMID 21509758 DOI: 10.1002/Cncr.25595  0.336
2010 Grimaldi-Bensouda L, Marty M, Pollak M, Cameron D, Riddle M, Charbonnel B, Barnett AH, Boffetta P, Boivin JF, Evans M, Rossignol M, Benichou J, Abenhaim L. The international study of insulin and cancer. Lancet (London, England). 376: 769-70. PMID 20816540 DOI: 10.1016/S0140-6736(10)61374-8  0.408
2010 Pollak M. Metformin and other biguanides in oncology: advancing the research agenda. Cancer Prevention Research (Philadelphia, Pa.). 3: 1060-5. PMID 20810670 DOI: 10.1158/1940-6207.Capr-10-0175  0.323
2010 Thomas JA, Antonelli JA, Lloyd JC, Masko EM, Poulton SH, Phillips TE, Pollak M, Freedland SJ. Effect of intermittent fasting on prostate cancer tumor growth in a mouse model Prostate Cancer and Prostatic Diseases. 13: 350-355. PMID 20733612 DOI: 10.1038/Pcan.2010.24  0.392
2010 Douglas JB, Silverman DT, Pollak MN, Tao Y, Soliman AS, Stolzenberg-Solomon RZ. Serum IGF-I, IGF-II, IGFBP-3, and IGF-I/IGFBP-3 molar ratio and risk of pancreatic cancer in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 2298-306. PMID 20699371 DOI: 10.1158/1055-9965.Epi-10-0400  0.326
2010 Furic L, Rong L, Larsson O, Koumakpayi IH, Yoshida K, Brueschke A, Petroulakis E, Robichaud N, Pollak M, Gaboury LA, Pandolfi PP, Saad F, Sonenberg N. eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression. Proceedings of the National Academy of Sciences of the United States of America. 107: 14134-9. PMID 20679199 DOI: 10.1073/Pnas.1005320107  0.371
2010 Johnson JA, Pollak M. Insulin, glucose and the increased risk of cancer in patients with type 2 diabetes Diabetologia. 53: 2086-2088. PMID 20645073 DOI: 10.1007/S00125-010-1855-0  0.421
2010 Canzian F, Cox DG, Setiawan VW, Stram DO, Ziegler RG, Dossus L, Beckmann L, Blanché H, Barricarte A, Berg CD, Bingham S, Buring J, Buys SS, Calle EE, Chanock SJ, ... ... Pollak M, et al. Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium. Human Molecular Genetics. 19: 3873-84. PMID 20634197 DOI: 10.1093/Hmg/Ddq291  0.427
2010 Giovannucci E, Harlan DM, Archer MC, Bergenstal RM, Gapstur SM, Habel LA, Pollak M, Regensteiner JG, Yee D. Diabetes and cancer: a consensus report. Diabetes Care. 33: 1674-85. PMID 20587728 DOI: 10.2337/Dc10-0666  0.351
2010 Hou M, Venier N, Sugar L, Musquera M, Pollak M, Kiss A, Fleshner N, Klotz L, Venkateswaran V. Protective effect of metformin in CD1 mice placed on a high carbohydrate-high fat diet. Biochemical and Biophysical Research Communications. 397: 537-42. PMID 20573602 DOI: 10.1016/J.Bbrc.2010.05.152  0.352
2010 Inoue T, Zakikhani M, David S, Algire C, Blouin MJ, Pollak M. Effects of castration on insulin levels and glucose tolerance in the mouse differ from those in man. The Prostate. 70: 1628-35. PMID 20564323 DOI: 10.1002/Pros.21198  0.396
2010 Giovannucci E, Harlan DM, Archer MC, Bergenstal RM, Gapstur SM, Habel LA, Pollak M, Regensteiner JG, Yee D. Diabetes and cancer: a consensus report. Ca: a Cancer Journal For Clinicians. 60: 207-21. PMID 20554718 DOI: 10.3322/Caac.20078  0.32
2010 Pollak M. Beyond steroid hormones: the new cancer endocrinology. Lancet Oncology. 11: 501-502. PMID 20472502 DOI: 10.1016/S1470-2045(10)70116-9  0.354
2010 Mireuta M, Darnel A, Pollak M. IGFBP-2 expression in MCF-7 cells is regulated by the PI3K/AKT/mTOR pathway through Sp1-induced increase in transcription. Growth Factors Journal. 28: 243-255. PMID 20370577 DOI: 10.3109/08977191003745472  0.341
2010 Algire C, Amrein L, Zakikhani M, Panasci L, Pollak M. Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase Endocrine-Related Cancer. 17: 351-360. PMID 20228137 DOI: 10.1677/Erc-09-0252  0.364
2010 Pollak M, Russell-Jones D. Insulin analogues and cancer risk: cause for concern or cause célèbre? International Journal of Clinical Practice. 64: 628-36. PMID 20201993 DOI: 10.1111/j.1742-1241.2010.02354.x  0.319
2010 Neuhouser ML, Till C, Kristal A, Goodman P, Hoque A, Platz EA, Hsing AW, Albanes D, Parnes HL, Pollak M. Finasteride modifies the relation between serum C-peptide and prostate cancer risk: results from the Prostate Cancer Prevention Trial. Cancer Prevention Research (Philadelphia, Pa.). 3: 279-89. PMID 20179296 DOI: 10.1158/1940-6207.Capr-09-0188  0.371
2010 Mucci LA, Stark JR, Pollak MN, Li H, Kurth T, Stampfer MJ, Ma J. Plasma levels of acid-labile subunit, free insulin-like growth factor-I, and prostate cancer risk: a prospective study. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 484-91. PMID 20142246 DOI: 10.1158/1055-9965.EPI-09-0836  0.32
2010 Flaig TW, Glodé M, Gustafson D, Van Bokhoven A, Tao Y, Wilson S, Su LJ, Li Y, Harrison G, Agarwal R, Crawford ED, Lucia MS, Pollak M. A study of high-dose oral silybin-phytosome followed by prostatectomy in patients with localized prostate cancer Prostate. 70: 848-855. PMID 20127732 DOI: 10.1002/Pros.21118  0.323
2010 Khalid S, Hwang D, Babichev Y, Kolli R, Altamentova S, Koren S, Goodwin PJ, Ennis M, Pollak M, Sonenberg N, Fantus IG. Evidence for a tumor promoting effect of high-fat diet independent of insulin resistance in HER2/Neu mammary carcinogenesis. Breast Cancer Research and Treatment. 122: 647-59. PMID 19851863 DOI: 10.1007/S10549-009-0586-8  0.337
2010 Blouin MJ, Zhao Y, Zakikhani M, Algire C, Piura E, Pollak M. Loss of function of PTEN alters the relationship between glucose concentration and cell proliferation, increases glycolysis, and sensitizes cells to 2-deoxyglucose. Cancer Letters. 289: 246-53. PMID 19744772 DOI: 10.1016/J.Canlet.2009.08.021  0.307
2010 Medyouf H, Gusscott S, Wai C, Nemirovsky O, Giambra V, Carboni JM, Gottardis M, Pflumio F, Pollak M, Holzenberger M, Weng AP. High-Level IGF1R Expression Is Required for Leukemia Stem Cell Activity In T-ALL and Is Supported by Notch Signaling. Blood. 116: 3649-3649. DOI: 10.1182/Blood.V116.21.3649.3649  0.308
2010 Wu K, Feskanich D, Fuchs C, Chan A, Willett W, Hollis B, Pollak M, Giovannucci E. Abstract PR-04: Interactions between plasma levels of 25-hydroxyvitamin D and insulin-like growth factor (IGF)-1, IGF-binding proteins and C-peptide with risk of colorectal cancer Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-Pr-04  0.378
2010 Nimptsch K, Platz E, Pollak M, Willett W, Giovannucci E. Abstract B115: Plasma insulin‐like growth factor 1, binding protein‐3, and risk of prostate cancer: An update from the Health Professional Follow‐up Study 1993–2004 Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-B115  0.388
2010 Algire C, Amrein L, Bazile M, Zakikhani M, David S, Pollak M. Abstract 65: Metformin inhibits in vivo growth of MC38 colon carcinoma in the absence of LKB1 expression Cancer Research. 70: 65-65. DOI: 10.1158/1538-7445.Am10-65  0.35
2010 Potratz J, Saunders D, Wai D, Reynolds CP, Buckley JD, Arceci RJ, Reaman GH, Triche TJ, Jürgens H, Pollak M, Sorensen PH. Abstract 3422: Synthetic lethal siRNA screening reveals novel modifiers of insulin-like growth factor-1 receptor (IGF1R) inhibitor activity in childhood sarcomas Cancer Research. 70: 3422-3422. DOI: 10.1158/1538-7445.Am10-3422  0.354
2010 Colquhoun AJ, Venier NA, Fleshner NE, Pollak M, Klotz LH, Venkateswaran V. Abstract 1799: Utilizing metformin to enhance the efficacy of androgen deprivation therapy in the treatment of prostate cancer Cancer Research. 70: 1799-1799. DOI: 10.1158/1538-7445.Am10-1799  0.413
2010 Ali S, Aguilar-Mahecha A, Chapman J, Lipton A, Leitzel K, Jahan K, Hassan S, Shepherd L, Han L, Wilson C, Pritchard K, Pollak M, Basik M. Abstract P4-09-09: Serum SDF-1: Biomarker of Bone Relapse in the NCIC MA.14 Adjuvant Breast Cancer Trial Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P4-09-09  0.306
2010 Colquhoun A, Venier N, Fleshner N, Pollak M, Klotz L, Venkateswaran V. 99 Utilizing Metformin To Enhance The Efficacy Of Androgen Deprivation Therapy In The Treatment Of Prostate Cancer The Journal of Urology. 185: 219. DOI: 10.1016/J.Juro.2010.02.148  0.369
2010 Antonelli J, Jones L, Thomas J, Masko E, Lloyd J, Poulton S, Phillips T, Tewari A, Febbo P, Pollak M, Dewhirst M, Freedland SJ. 89 Effect Of Voluntary Wheel Running On Growth Of Prostate Cancer In Immunocompromised And Immunocompetent Mouse Models The Journal of Urology. 183. DOI: 10.1016/J.Juro.2010.02.138  0.369
2010 Hou M, Venier N, Sugar L, Musquera M, Pollak M, Fleshner N, Klotz L, Venkateswaran V. 1434 Role Of Metformin In Prostate Cancer Progression: Mechanistic Studies In A Xenograft Model The Journal of Urology. 183. DOI: 10.1016/J.Juro.2010.02.1127  0.346
2009 Gualberto A, Pollak M. Clinical development of inhibitors of the insulin-like growth factor receptor in oncology. Current Drug Targets. 10: 923-936. PMID 19663769 DOI: 10.2174/138945009789577945  0.43
2009 Pollak M. Macronutrient intake and cancer: how does dietary restriction influence tumor growth and why should we care? Cancer Prevention Research (Philadelphia, Pa.). 2: 698-701. PMID 19654107 DOI: 10.1158/1940-6207.Capr-09-0134  0.351
2009 Gualberto A, Pollak M. Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions. Oncogene. 28: 3009-3021. PMID 19581933 DOI: 10.1038/Onc.2009.172  0.384
2009 Dowling RJ, Pollak M, Sonenberg N. Current status and challenges associated with targeting mTOR for cancer therapy. Biodrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. 23: 77-91. PMID 19489650 DOI: 10.2165/00063030-200923020-00002  0.375
2009 Mavropoulos JC, Buschemeyer WC, Tewari AK, Rokhfeld D, Pollak M, Zhao Y, Febbo PG, Cohen P, Hwang D, Devi G, Demark-Wahnefried W, Westman EC, Peterson BL, Pizzo SV, Freedland SJ. The effects of varying dietary carbohydrate and fat content on survival in a murine LNCaP prostate cancer xenograft model. Cancer Prevention Research (Philadelphia, Pa.). 2: 557-65. PMID 19470786 DOI: 10.1158/1940-6207.Capr-08-0188  0.396
2009 Pollak M. Do cancer cells care if their host is hungry? Cell Metabolism. 9: 401-3. PMID 19416708 DOI: 10.1016/J.Cmet.2009.04.006  0.407
2009 Pollak M. Aging, IGF-1, and diet Aging Cell. 8: 214-214. PMID 19281498 DOI: 10.1111/J.1474-9726.2009.00450.X  0.38
2009 Avnet S, Sciacca L, Salerno M, Gancitano G, Cassarino MF, Longhi A, Zakikhani M, Carboni JM, Gottardis M, Giunti A, Pollak M, Vigneri R, Baldini N. Insulin Receptor Isoform A and Insulin-like Growth Factor II as Additional Treatment Targets in Human Osteosarcoma Cancer Research. 69: 2443-2452. PMID 19258511 DOI: 10.1158/0008-5472.Can-08-2645  0.395
2009 Pollak M. Energy metabolism, cancer risk, and cancer prevention. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer. 181: 51-4. PMID 19213556 DOI: 10.1007/978-3-540-69297-3_5  0.365
2009 Cox ME, Gleave ME, Zakikhani M, Bell RH, Piura E, Vickers E, Cunningham M, Larsson O, Fazli L, Pollak M. Insulin receptor expression by human prostate cancers. The Prostate. 69: 33-40. PMID 18785179 DOI: 10.1002/Pros.20852  0.393
2009 Ali S, Chapman J, Lipton A, Leitzel K, Pritchard K, Pu X, Wilson C, Carney W, Shepherd L, Pollak M. Examination of TIMP-1 Levels and Relapse-Free Survival for Patients in NCIC CTG MA.14 Who Received Adjuvant Tamoxifen +/- Octreotide LAR. Cancer Research. 69: 3022-3022. DOI: 10.1158/0008-5472.Sabcs-09-3022  0.307
2009 Pollak M. Erratum: Insulin and insulin-like growth factor signalling in neoplasia (Erratum) Nature Reviews Cancer. 9: 224-224. DOI: 10.1038/Nrc2605  0.427
2009 Saad F, Hotte S, North S, Eigl B, Chi K, Czaykowski P, Pollak M, Wood L, Winquist E. CUOG PHASE II RANDOMIZED STUDY OF CUSTIRSEN (OGX-011) COMBINATION THERAPY IN PATIENTS WITH CASTRATE RESISTANT PROSTATE CANCER (CRPC) WHO RELAPSED ON OR WITHIN SIX MONTHS OF 1ST-LINE DOCETAXEL THERAPY Journal of Urology. 181: 229-230. DOI: 10.1016/S0022-5347(09)60654-6  0.303
2009 Freedland SJ, Mavropoulos JC, Buschemeyer WC, Tewari AK, Rokhfeld D, Pollak M, Zhao Y, Febbo PG, Cohen P, Hwang D, Devi G, Demark-Wahnefried W, Westman EC, Peterson BL, Pizzo SV. A NO CARBOHYDRATE DIET SIGNIFICANTLY PROLONGS SURVIVAL IN A PROSTATE CANCER XENOGRAFT MODEL VIA IGF-1 AND GLOBAL GENE EXPRESSION CHANGES Journal of Urology. 181: 47-47. DOI: 10.1016/S0022-5347(09)60144-0  0.354
2008 Pollak MN, Chapman JW, Pritchard KI, Krook JE, Dhaliwal HS, Vandenberg TA, Norris BD, Whelan TJ, Wilson CF, Shepherd LE. NCIC-CTG MA14 Trial: Tamoxifen (tam) vs. tam + octreotide (oct) for adjuvant treatment of stage I or II postmenopausal breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 532. PMID 27948402 DOI: 10.1200/jco.2008.26.15_suppl.532  0.303
2008 Law JH, Habibi G, Hu K, Masoudi H, Wang MY, Stratford AL, Park E, Gee JM, Finlay P, Jones HE, Nicholson RI, Carboni J, Gottardis M, Pollak M, Dunn SE. Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival. Cancer Research. 68: 10238-46. PMID 19074892 DOI: 10.1158/0008-5472.Can-08-2755  0.424
2008 Fuchs CS, Goldberg RM, Sargent DJ, Meyerhardt JA, Wolpin BM, Green EM, Pitot HC, Pollak M. Plasma insulin-like growth factors, insulin-like binding protein-3, and outcome in metastatic colorectal cancer: results from intergroup trial N9741. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 8263-9. PMID 19073970 DOI: 10.1158/1078-0432.Ccr-08-0480  0.426
2008 Wolpin BM, Meyerhardt JA, Chan AT, Ng K, Chan JA, Wu K, Pollak MN, Giovannucci EL, Fuchs CS. Insulin, the insulin-like growth factor axis, and mortality in patients with nonmetastatic colorectal cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 176-85. PMID 19064975 DOI: 10.1200/JCO.2008.17.9945  0.324
2008 Pollak M. Insulin and insulin-like growth factor signalling in neoplasia. Nature Reviews Cancer. 8: 915-928. PMID 19029956 DOI: 10.1038/Nrc2536  0.432
2008 So AI, Levitt RJ, Eigl B, Fazli L, Muramaki M, Leung S, Cheang MC, Nielsen TO, Gleave M, Pollak M. Insulin-like growth factor binding protein-2 is a novel therapeutic target associated with breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 6944-54. PMID 18980989 DOI: 10.1158/1078-0432.Ccr-08-0408  0.45
2008 Pollak M. Insulin, insulin-like growth factors and neoplasia. Best Practice & Research Clinical Endocrinology & Metabolism. 22: 625-638. PMID 18971123 DOI: 10.1016/J.Beem.2008.08.004  0.457
2008 Chitnis MM, Yuen JSP, Protheroe AS, Pollak M, Macaulay VM. The type 1 insulin-like growth factor receptor pathway. Clinical Cancer Research. 14: 6364-6370. PMID 18927274 DOI: 10.1158/1078-0432.Ccr-07-4879  0.397
2008 Habibi G, Leung S, Law JH, Gelmon K, Masoudi H, Turbin D, Pollak M, Nielsen TO, Huntsman D, Dunn SE. Redefining prognostic factors for breast cancer: YB-1 is a stronger predictor of relapse and disease-specific survival than estrogen receptor or HER-2 across all tumor subtypes. Breast Cancer Research : Bcr. 10: R86. PMID 18925950 DOI: 10.1186/Bcr2156  0.376
2008 Roddam AW, Allen NE, Appleby P, Key TJ, Ferrucci L, Carter HB, Metter EJ, Chen C, Weiss NS, Fitzpatrick A, Hsing AW, Lacey JV, Helzlsouer K, Rinaldi S, Riboli E, ... ... Pollak M, et al. Insulin-like growth factors, their binding proteins, and prostate cancer risk: analysis of individual patient data from 12 prospective studies. Annals of Internal Medicine. 149: 461-71, W83-8. PMID 18838726 DOI: 10.7326/0003-4819-149-7-200810070-00006  0.435
2008 Ma J, Li H, Giovannucci E, Mucci L, Qiu W, Nguyen PL, Gaziano JM, Pollak M, Stampfer MJ. Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: a long-term survival analysis. The Lancet. Oncology. 9: 1039-47. PMID 18835745 DOI: 10.1016/S1470-2045(08)70235-3  0.339
2008 Stolzenberg-Solomon RZ, Weinstein S, Pollak M, Tao Y, Taylor PR, Virtamo J, Albanes D. Prediagnostic adiponectin concentrations and pancreatic cancer risk in male smokers. American Journal of Epidemiology. 168: 1047-55. PMID 18801887 DOI: 10.1093/Aje/Kwn221  0.357
2008 Diorio C, Sinotte M, Brisson J, Bérubé S, Pollak M. Vitamin D pathway polymorphisms in relation to mammographic breast density. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 2505-8. PMID 18768522 DOI: 10.1158/1055-9965.Epi-08-0493  0.326
2008 Pollak M. Targeting insulin and insulin-like growth factor signalling in oncology. Current Opinion in Pharmacology. 8: 384-92. PMID 18674638 DOI: 10.1016/J.Coph.2008.07.004  0.362
2008 Max JB, Limburg PJ, Ogunseitan A, Stolzenberg-Solomon RZ, Vierkant RA, Pollak MJ, Sellers TA, Virtamo J, Cerhan JR, Albanes D. IGF-I, IGFBP-3, and IGF-I/IGFBP-3 ratio: No association with incident colorectal cancer in the alpha-tocopherol, beta-carotene cancer prevention study Cancer Epidemiology, Biomarkers & Prevention. 17: 1832-1834. PMID 18628438 DOI: 10.1158/1055-9965.Epi-08-0345  0.309
2008 Neuhouser ML, Schenk J, Song YJ, Tangen CM, Goodman PJ, Pollak M, Penson DF, Thompson IM, Kristal AR. Insulin-like growth factor-I, insulin-like growth factor binding protein-3 and risk of benign prostate hyperplasia in the prostate cancer prevention trial. The Prostate. 68: 1477-86. PMID 18618736 DOI: 10.1002/Pros.20819  0.401
2008 Patel AV, Cheng I, Canzian F, Le Marchand L, Thun MJ, Berg CD, Buring J, Calle EE, Chanock S, Clavel-Chapelon F, Cox DG, Dorronsoro M, Dossus L, Haiman CA, Hankinson SE, ... ... Pollak M, et al. IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3). Plos One. 3: e2578. PMID 18596909 DOI: 10.1371/Journal.Pone.0002578  0.44
2008 Diorio C, Brisson J, Bérubé S, Pollak M. Intact and total insulin-like growth factor-binding protein-3 (IGFBP-3) levels in relation to breast cancer risk factors: a cross-sectional study. Breast Cancer Research : Bcr. 10: R42. PMID 18471292 DOI: 10.1186/Bcr2093  0.439
2008 Algire C, Zakikhani M, Blouin MJ, Shuai JH, Pollak M. Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth. Endocrine-Related Cancer. 15: 833-9. PMID 18469156 DOI: 10.1677/Erc-08-0038  0.32
2008 Gunter MJ, Hoover DR, Yu H, Wassertheil-Smoller S, Manson JE, Li J, Harris TG, Rohan TE, Xue X, Ho GYF, Einstein MH, Kaplan RC, Burk RD, Wylie-Rosett J, Pollak MN, et al. A prospective evaluation of insulin and insulin-like growth factor-I as risk factors for endometrial cancer Cancer Epidemiology Biomarkers and Prevention. 17: 921-929. PMID 18398032 DOI: 10.1158/1055-9965.Epi-07-2686  0.315
2008 Diorio C, Brisson J, Bérubé S, Pollak M. Genetic polymorphisms involved in insulin-like growth factor (IGF) pathway in relation to mammographic breast density and IGF levels. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 880-8. PMID 18398029 DOI: 10.1158/1055-9965.Epi-07-2500  0.403
2008 Borugian MJ, Spinelli JJ, Sun Z, Kolonel LN, Oakley-Girvan I, Pollak MD, Whittemore AS, Wu AH, Gallagher RP. Prostate cancer risk in relation to insulin-like growth factor (IGF)-I and IGF-binding protein-3: a prospective multiethnic study. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 252-4. PMID 18199733 DOI: 10.1158/1055-9965.Epi-07-2694  0.34
2008 Rajpathak SN, McGinn AP, Strickler HD, Rohan TE, Pollak M, Cappola AR, Kuller L, Xue X, Newman AB, Strotmeyer ES, Psaty BM, Kaplan RC. Insulin-like growth factor-(IGF)-axis, inflammation, and glucose intolerance among older adults. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 18: 166-73. PMID 17904401 DOI: 10.1016/J.Ghir.2007.08.004  0.339
2007 Venkateswaran V, Haddad AQ, Fleshner NE, Fan R, Sugar LM, Nam R, Klotz LH, Pollak M. Association of diet-induced hyperinsulinemia with accelerated growth of prostate cancer (LNCaP) xenografts. Journal of the National Cancer Institute. 99: 1793-800. PMID 18042933 DOI: 10.1093/Jnci/Djm231  0.359
2007 Dowling RJ, Zakikhani M, Fantus IG, Pollak M, Sonenberg N. Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells. Cancer Research. 67: 10804-12. PMID 18006825 DOI: 10.1158/0008-5472.Can-07-2310  0.363
2007 Tworoger SS, Lee IM, Buring JE, Pollak MN, Hankinson SE. Insulin-like growth factors and ovarian cancer risk: a nested case-control study in three cohorts. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 1691-5. PMID 17684148 DOI: 10.1158/1055-9965.EPI-07-0319  0.303
2007 Li H, Bubley GJ, Balk SP, Gaziano JM, Pollak M, Stampfer MJ, Ma J. Hypoxia-inducible factor-1alpha (HIF-1alpha) gene polymorphisms, circulating insulin-like growth factor binding protein (IGFBP)-3 levels and prostate cancer. The Prostate. 67: 1354-61. PMID 17624927 DOI: 10.1002/Pros.20589  0.39
2007 Levitt RJ, Zhao Y, Blouin MJ, Pollak M. The hedgehog pathway inhibitor cyclopamine increases levels of p27, and decreases both expression of IGF-II and activation of Akt in PC-3 prostate cancer cells. Cancer Letters. 255: 300-6. PMID 17602833 DOI: 10.1016/J.Canlet.2007.05.006  0.382
2007 Wolpin BM, Michaud DS, Giovannucci EL, Schernhammer ES, Stampfer MJ, Manson JE, Cochrane BB, Rohan TE, Ma J, Pollak MN, Fuchs CS. Circulating insulin-like growth factor axis and the risk of pancreatic cancer in four prospective cohorts British Journal of Cancer. 97: 98-104. PMID 17533398 DOI: 10.1038/Sj.Bjc.6603826  0.317
2007 Lönn S, Inskip PD, Pollak MN, Weinstein SJ, Virtamo J, Albanes D. Glioma risk in relation to serum levels of insulin-like growth factors. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 844-6. PMID 17416782 DOI: 10.1158/1055-9965.EPI-06-1010  0.314
2007 McSorley MA, Alberg AJ, Allen DS, Allen NE, Brinton LA, Dorgan JF, Pollak M, Tao Y, Helzlsouer KJ. C-reactive protein concentrations and subsequent ovarian cancer risk. Obstetrics and Gynecology. 109: 933-41. PMID 17400857 DOI: 10.1097/01.Aog.0000257126.68803.03  0.325
2007 Pollak M. Insulin-like growth factor-related signaling and cancer development. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer. 174: 49-53. PMID 17302184 DOI: 10.1007/978-3-540-37696-5_4  0.439
2007 de Bono JS, Adjei A, Attard G, Pollak M, Fong P, Haluska P, Roberts L, Chainese D, Terstappen L, Gualberto A. Circulating tumor cells expressing the insulin growth factor-1 receptor (IGF-1R): Method of detection, incidence and potential applications Journal of Clinical Oncology. 25: 3507-3507. DOI: 10.1200/Jco.2007.25.18_Suppl.3507  0.347
2007 Lacy MQ, Alsina M, Roberts L, Fonseca R, Melvin C, Yin D, Sharma A, Pollak M, Jagannath S, Richardson P, Gualberto A. Phase 1 Dose Escalation Study of the Monoclonal Antibody Against the Insulin Like Growth Factor I Receptor CP-751,871 in Patients with Multiple Myeloma. Blood. 110: 1171-1171. DOI: 10.1182/Blood.V110.11.1171.1171  0.317
2006 Tran CD, Diorio C, Bérubé S, Pollak M, Brisson J. Relation of insulin-like growth factor (IGF) I and IGF-binding protein 3 concentrations with intakes of fruit, vegetables, and antioxidants. The American Journal of Clinical Nutrition. 84: 1518-26. PMID 17158438 DOI: 10.1093/Ajcn/84.6.1518  0.335
2006 Zakikhani M, Dowling R, Fantus IG, Sonenberg N, Pollak M. Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells. Cancer Research. 66: 10269-73. PMID 17062558 DOI: 10.1158/0008-5472.Can-06-1500  0.438
2006 Tseng PH, Wang YC, Weng SC, Weng JR, Chen CS, Brueggemeier RW, Shapiro CL, Chen CY, Dunn SE, Pollak M, Chen CS. Overcoming trastuzumab resistance in HER2-overexpressing breast cancer cells by using a novel celecoxib-derived phosphoinositide-dependent kinase-1 inhibitor. Molecular Pharmacology. 70: 1534-41. PMID 16887935 DOI: 10.1124/Mol.106.023911  0.399
2006 Schernhammer ES, Holly JM, Hunter DJ, Pollak MN, Hankinson SE. Insulin-like growth factor-I, its binding proteins (IGFBP-1 and IGFBP-3), and growth hormone and breast cancer risk in The Nurses Health Study II. Endocrine-Related Cancer. 13: 583-92. PMID 16728584 DOI: 10.1677/ERC.1.01149  0.316
2006 Diorio C, Bérubé S, Byrne C, Mâsse B, Hébert-Croteau N, Yaffe M, Coté G, Pollak M, Brisson J. Influence of insulin-like growth factors on the strength of the relation of vitamin D and calcium intakes to mammographic breast density. Cancer Research. 66: 588-97. PMID 16397276 DOI: 10.1158/0008-5472.Can-05-1959  0.357
2006 Gotlieb WH, Bruchim I, Gu J, Shi Y, Camirand A, Blouin MJ, Zhao Y, Pollak MN. Insulin-like growth factor receptor I targeting in epithelial ovarian cancer. Gynecologic Oncology. 100: 389-96. PMID 16300820 DOI: 10.1016/j.ygyno.2005.09.048  0.322
2006 Rollison DE, Newschaffer CJ, Tao Y, Pollak M, Helzlsouer KJ. Premenopausal levels of circulating insulin-like growth factor I and the risk of postmenopausal breast cancer. International Journal of Cancer. Journal International Du Cancer. 118: 1279-84. PMID 16161053 DOI: 10.1002/Ijc.21471  0.423
2006 Rich-Edwards J, Ganmaa D, Pollak M, Nakamoto E, Willett W, Frazier L. Bioactive Factors in Cow's Milk Raise Levels of Growth Hormone and insulin-Like Growth Factor I in Prepubertal Girls American Journal of Epidemiology. 163: S103-S103. DOI: 10.1093/Aje/163.Suppl_11.S103-A  0.367
2005 So AI, Eigl B, Fazli L, Hunstman D, Ivanonv N, Pollak M, Dunn S, Gleave M. Significance of insulin-like growth factor binding protein-2 in the prognosis of breast cancer and promotion of accelerated growth and chemo-resistance in MDAMB-231 breast cancer model. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 542. PMID 27946431 DOI: 10.1200/Jco.2005.23.16_Suppl.542  0.449
2005 Diorio C, Pollak M, Byrne C, Mâsse B, Hébert-Croteau N, Yaffe M, Coté G, Bérubé S, Brisson J. Levels of C-peptide and mammographic breast density. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 2661-4. PMID 16284393 DOI: 10.1158/1055-9965.Epi-05-0466  0.345
2005 Kucab JE, Lee C, Chen CS, Zhu J, Gilks CB, Cheang M, Huntsman D, Yorida E, Emerman J, Pollak M, Dunn SE. Celecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumours. Breast Cancer Research : Bcr. 7: R796-807. PMID 16168126 DOI: 10.1186/Bcr1294  0.408
2005 Levitt RJ, Georgescu MM, Pollak M. PTEN-induction in U251 glioma cells decreases the expression of insulin-like growth factor binding protein-2. Biochemical and Biophysical Research Communications. 336: 1056-61. PMID 16154532 DOI: 10.1016/J.Bbrc.2005.08.229  0.391
2005 Bérubé S, Diorio C, Mâsse B, Hébert-Croteau N, Byrne C, Côté G, Pollak M, Yaffe M, Brisson J. Vitamin D and calcium intakes from food or supplements and mammographic breast density. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 1653-9. PMID 16030097 DOI: 10.1158/1055-9965.Epi-05-0068  0.31
2005 Camirand A, Zakikhani M, Young F, Pollak M. Inhibition of insulin-like growth factor-1 receptor signaling enhances growth-inhibitory and proapoptotic effects of gefitinib (Iressa) in human breast cancer cells. Breast Cancer Research : Bcr. 7: R570-9. PMID 15987464 DOI: 10.1186/Bcr1028  0.432
2005 Platz EA, Pollak MN, Leitzmann MF, Stampfer MJ, Willett WC, Giovannucci E. Plasma insulin-like growth factor-1 and binding protein-3 and subsequent risk of prostate cancer in the PSA era Cancer Causes and Control. 16: 255-262. PMID 15947877 DOI: 10.1007/S10552-004-3484-8  0.312
2005 Meyerhardt JA, Sloan JA, Sargent DJ, Goldberg RM, Pollak M, Morton RF, Ramanathan RK, Williamson SK, Findlay BP, Fuchs CS. Associations between plasma insulin-like growth factor proteins and C-peptide and quality of life in patients with metastatic colorectal cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 1402-10. PMID 15941948 DOI: 10.1158/1055-9965.Epi-04-0862  0.392
2005 Nam RK, Trachtenberg J, Jewett MA, Toi A, Evans A, Emami M, Narod SA, Pollak M. Serum insulin-like growth factor-I levels and prostatic intraepithelial neoplasia: a clue to the relationship between IGF-I physiology and prostate cancer risk. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 1270-3. PMID 15894684 DOI: 10.1158/1055-9965.Epi-04-0430  0.387
2005 Diorio C, Pollak M, Byrne C, Mâsse B, Hébert-Croteau N, Yaffe M, Coté G, Bérubé S, Morin C, Brisson J. Insulin-like growth factor-I, IGF-binding protein-3, and mammographic breast density. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 1065-73. PMID 15894654 DOI: 10.1158/1055-9965.Epi-04-0706  0.374
2005 Majeed N, Blouin MJ, Kaplan-Lefko PJ, Barry-Shaw J, Greenberg NM, Gaudreau P, Bismar TA, Pollak M. A germ line mutation that delays prostate cancer progression and prolongs survival in a murine prostate cancer model. Oncogene. 24: 4736-40. PMID 15870705 DOI: 10.1038/Sj.Onc.1208572  0.396
2005 Wei EK, Ma J, Pollak MN, Rifai N, Fuchs CS, Hankinson SE, Giovannucci E. A prospective study of C-peptide, insulin-like growth factor-I, insulin-like growth factor binding protein-1, and the risk of colorectal cancer in women. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 850-5. PMID 15824155 DOI: 10.1158/1055-9965.EPI-04-0661  0.328
2005 Sutherland BW, Kucab J, Wu J, Lee C, Cheang MC, Yorida E, Turbin D, Dedhar S, Nelson C, Pollak M, Leighton Grimes H, Miller K, Badve S, Huntsman D, Blake-Gilks C, et al. Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells. Oncogene. 24: 4281-92. PMID 15806160 DOI: 10.1038/Sj.Onc.1208590  0.369
2005 Schernhammer ES, Holly JM, Pollak MN, Hankinson SE. Circulating levels of insulin-like growth factors, their binding proteins, and breast cancer risk. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 699-704. PMID 15767352 DOI: 10.1158/1055-9965.EPI-04-0561  0.34
2005 Canil CM, Moore MJ, Winquist E, Baetz T, Pollak M, Chi KN, Berry S, Ernst DS, Douglas L, Brundage M, Fisher B, McKenna A, Seymour L. Randomized phase II study of two doses of gefitinib in hormone-refractory prostate cancer: a trial of the National Cancer Institute of Canada-Clinical Trials Group. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 455-60. PMID 15659491 DOI: 10.1200/Jco.2005.02.129  0.374
2005 Pollak M. Individualizing interventions for cancer prevention. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer. 166: 63-9. PMID 15648183 DOI: 10.1007/3-540-26980-0_5  0.302
2004 Pollak MN. Insulin-like growth factors and neoplasia. Novartis Foundation Symposium. 262: 84-98; discussion 98. PMID 15562824  0.356
2004 Camirand A, Pollak M. Co-targeting IGF-1R and c-kit: synergistic inhibition of proliferation and induction of apoptosis in H 209 small cell lung cancer cells. British Journal of Cancer. 90: 1825-9. PMID 15150607 DOI: 10.1038/Sj.Bjc.6601682  0.357
2004 Ma J, Giovannucci E, Pollak M, Leavitt A, Tao Y, Gaziano JM, Stampfer MJ. A prospective study of plasma C-peptide and colorectal cancer risk in men. Journal of the National Cancer Institute. 96: 546-553. PMID 15069117 DOI: 10.1093/Jnci/Djh082  0.392
2004 Levitt RJ, Buckley J, Blouin MJ, Schaub B, Triche TJ, Pollak M. Growth inhibition of breast epithelial cells by celecoxib is associated with upregulation of insulin-like growth factor binding protein-3 expression. Biochemical and Biophysical Research Communications. 316: 421-8. PMID 15020235 DOI: 10.1016/J.Bbrc.2004.02.062  0.437
2004 Stolzenberg-Solomon RZ, Limburg P, Pollak M, Taylor PR, Virtamo J, Albanes D. Insulin-like growth factor (IGF)-1, IGF-binding protein-3, and pancreatic cancer in male smokers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 13: 438-44. PMID 15006921  0.311
2004 Labrie F, Champagne P, Labrie C, Roy J, Laverdière J, Provencher L, Potvin M, Drolet Y, Pollak M, Panasci L, L'Espérance B, Dufresne J, Latreille J, Robert J, Samson B, et al. Activity and safety of the antiestrogen EM-800, the orally active precursor of acolbifene, in tamoxifen-resistant breast cancer Journal of Clinical Oncology. 22: 864-871. PMID 14990642 DOI: 10.1200/Jco.2004.05.122  0.348
2004 Lu Y, Zi X, Zhao Y, Pollak M. Overexpression of ErbB2 receptor inhibits IGF-I-induced Shc-MAPK signaling pathway in breast cancer cells. Biochemical and Biophysical Research Communications. 313: 709-15. PMID 14697248 DOI: 10.1016/J.Bbrc.2003.12.007  0.663
2004 Schairer C, Hill D, Sturgeon SR, Fears T, Pollak M, Mies C, Ziegler RG, Hoover RN, Sherman ME. Serum concentrations of IGF-I, IGFBP-3 and c-peptide and risk of hyperplasia and cancer of the breast in postmenopausal women. International Journal of Cancer. Journal International Du Cancer. 108: 773-9. PMID 14696106 DOI: 10.1002/Ijc.11624  0.415
2004 Lu Y, Zi X, Pollak M. Molecular mechanisms underlying IGF-I-induced attenuation of the growth-inhibitory activity of trastuzumab (Herceptin) on SKBR3 breast cancer cells. International Journal of Cancer. 108: 334-41. PMID 14648698 DOI: 10.1002/Ijc.11445  0.662
2003 Ismail HA, Pollak M, Behlouli H, Tanguay S, Bégin LR, Aprikian AG. Serum insulin-like growth factor (IGF)-1 and IGF-binding protein-3 do not correlate with Gleason score or quantity of prostate cancer in biopsy samples. Bju International. 92: 699-702. PMID 14616449 DOI: 10.1046/J.1464-410X.2003.04084.X  0.433
2003 Nomura AM, Stemmermann GN, Lee J, Pollak MN. Serum insulin-like growth factor I and subsequent risk of colorectal cancer among Japanese-American men. American Journal of Epidemiology. 158: 424-31. PMID 12936897 DOI: 10.1093/AJE/KWG176  0.329
2003 Woodson K, Tangrea JA, Pollak M, Copeland TD, Taylor PR, Virtamo J, Albanes D. Serum insulin-like growth factor I: Tumor marker or etiologic factor? A prospective study of prostate cancer among Finnish men Cancer Research. 63: 3991-3994. PMID 12873996  0.322
2003 Limburg P, Vierkant R, Stolzenberg-Solomon R, Sellers T, Pollak M, Virtamo J, Albanes D. Insulin, insulin-like growth factor proteins, and colorectal cancer risk in the ATBC study Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)80387-6  0.417
2002 Camirand A, Lu Y, Pollak M. Co-targeting HER2/ErbB2 and insulin-like growth factor-1 receptors causes synergistic inhibition of growth in HER2-overexpressing breast cancer cells. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 8: BR521-6. PMID 12503030  0.649
2002 Deitel K, Dantzer D, Ferguson P, Pollak M, Beamer W, Andrulis I, Bell R. Reduced growth of human sarcoma xenografts in hosts homozygous for the lit mutation. Journal of Surgical Oncology. 81: 75-9. PMID 12355407 DOI: 10.1002/Jso.10136  0.353
2002 Giovannucci E, Pollak M. Risk of cancer after growth-hormone treatment. Lancet (London, England). 360: 268-9. PMID 12147365 DOI: 10.1016/S0140-6736(02)09561-2  0.377
2002 Chan JM, Stampfer MJ, Ma J, Gann P, Gaziano JM, Pollak M, Giovannucci E. Re: Insulin-like growth factor-I (IGF-I) and IGF binding protein-3 as predictors of advanced-stage prostate cancer Journal of the National Cancer Institute. 94: 1099-1106. PMID 12122101 DOI: 10.1093/Jnci/94.14.1099  0.408
2002 Pollak M. Insulin-like growth factors and prostate cancer. Epidemiologic Reviews. 23: 59-66. PMID 11588855 DOI: 10.1023/A:1006154108619  0.425
2002 A HI, Pollak M, Behlouli H, Tanguay S, Bégin LR, Aprikian AG. Insulin-like growth factor-1 and insulin-like growth factor binding protein-3 for prostate cancer detection in patients undergoing prostate biopsy. The Journal of Urology. 168: 2426-2430. DOI: 10.1016/S0022-5347(05)64160-2  0.406
2001 Lu Y, Zi X, Zhao Y, Mascarenhas D, Pollak M. Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin). Journal of the National Cancer Institute. 93: 1852-7. PMID 11752009 DOI: 10.1093/Jnci/93.24.1852  0.678
2001 Tolcher AW, Kennedy A, Padley RJ, Majeed N, Pollak M, Kantoff PW. Other novel agents: Rationale and current status as chemopreventive agents Urology. 57: 86-89. PMID 11295602 DOI: 10.1016/S0090-4295(00)00948-1  0.345
2001 Deal C, Ma J, Wilkin F, Paquette J, Rozen F, Ge B, Hudson T, Stampfer M, Pollak M. Novel promoter polymorphism in insulin-like growth factor-binding protein-3: correlation with serum levels and interaction with known regulators. The Journal of Clinical Endocrinology and Metabolism. 86: 1274-1280. PMID 11238520 DOI: 10.1210/Jcem.86.3.7280  0.388
2001 Jernström H, Chu W, Vesprini D, Tao Y, Majeed N, Deal C, Pollak M, Narod SA. Genetic factors related to racial variation in plasma levels of insulin-like growth factor-1: implications for premenopausal breast cancer risk. Molecular Genetics and Metabolism. 72: 144-54. PMID 11161840 DOI: 10.1006/Mgme.2000.3130  0.356
2001 Chan JM, Stampfer MJ, Giovannucci E, Ma J, Pollak M. Insulin-like growth factor I (IGF-I), IGF-binding protein-3 and prostate cancer risk: epidemiological studies. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. S32-3. PMID 10984284 DOI: 10.1016/S1096-6374(00)90015-7  0.439
2001 Ma J, Pollak M, Giovannucci E, Chan JM, Tao Y, Hennekens C, Stampfer MJ. A prospective study of plasma levels of insulin-like growth factor I (IGF-I) and IGF-binding protein-3, and colorectal cancer risk among men. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. S28-9. PMID 10984282 DOI: 10.1016/S1096-6374(00)90013-3  0.422
2001 Byrne C, Hankinson SE, Pollak M, Willett WC, Colditz GA, Speizer FE. Insulin-like growth factors and mammographic density. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. S24-5. PMID 10984280 DOI: 10.1016/S1096-6374(00)90011-X  0.363
2001 Pollak M. Insulin-like growth factor physiology and neoplasia. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. S6-7. PMID 10984271 DOI: 10.1016/S1096-6374(00)90002-9  0.37
2001 Pollak M. The question of a link between insulin-like growth factor physiology and neoplasia. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. S21-4. PMID 10984249 DOI: 10.1016/S1096-6374(00)80005-2  0.426
2001 Ma J, Giovannucci E, Pollak M, Chan JM, Gaziano JM, Willett W, Stampfer MJ. Milk Intake, Circulating Levels of Insulin-Like Growth Factor-I, and Risk of Colorectal Cancer in Men Jnci Journal of the National Cancer Institute. 93: 1330-1336. DOI: 10.1093/Jnci/93.17.1330  0.415
2000 Nabholtz JM, Buzdar A, Pollak M, Harwin W, Burton G, Mangalik A, Steinberg M, Webster A, Euler MV. Anastrozole Is Superior to Tamoxifen as First-Line Therapy for Advanced Breast Cancer in Postmenopausal Women: Results of a North American Multicenter Randomized Trial Journal of Clinical Oncology. 18: 3758-3767. PMID 11078488 DOI: 10.1200/Jco.2000.18.22.3758  0.319
2000 Giovannucci E, Pollak M, Platz EA, Willett WC, Stampfer MJ, Majeed N, Colditz GA, Speizer FE, Hankinson SE. Insulin-like growth factor I (IGF-I), IGF-binding protein-3 and the risk of colorectal adenoma and cancer in the nurses' health study Growth Hormone and Igf Research. 10. PMID 10984283 DOI: 10.1016/S1096-6374(00)90014-5  0.391
2000 Pollak M. Insulin-like growth factor physiology and cancer risk. European Journal of Cancer (Oxford, England : 1990). 36: 1224-8. PMID 10882860 DOI: 10.1016/S0959-8049(00)00102-7  0.418
2000 Wilkin F, Paquette J, Ledru E, Mamelin C, Pollak M, Deal CL. H19 sense and antisense transgenes modify insulin-like growth factor-II mRNA levels. Febs Journal. 267: 4020-4027. PMID 10866801 DOI: 10.1046/J.1432-1327.2000.01438.X  0.317
2000 Huynh H, Beamer W, Pollak M, Chan TWMG. Modulation of transforming growth factor beta1 gene expression in the mammary gland by insulin-like growth factor I and octreotide. International Journal of Oncology. 16: 277-358. PMID 10639570 DOI: 10.3892/Ijo.16.2.277  0.323
2000 Pollak M, Besser GM, Cohen P, Rosenfeld RG. First International Workshop on Growth Hormone, Insulin-like Growth Factors and Neoplasia Growth Hormone & Igf Research. 10. DOI: 10.1016/S1096-6374(00)90000-5  0.367
1999 Nickerson T, Pollak M. Bicalutamide (Casodex)-induced prostate regression involves increased expression of genes encoding insulin-like growth factor binding proteins Urology. 54: 1120-1125. PMID 10604720 DOI: 10.1016/S0090-4295(99)00421-5  0.4
1999 Rozen F, Pollak M. Inhibition of insulin-like growth factor I receptor signaling by the vitamin D analogue EB1089 in MCF-7 breast cancer cells : A role for insulin-like growth factor binding proteins International Journal of Oncology. 15: 589-683. PMID 10427145 DOI: 10.3892/Ijo.15.3.589  0.426
1999 Rosen CJ, Pollak M. Circulating IGF-I: New Perspectives for a New Century. Trends in Endocrinology and Metabolism. 10: 136-141. PMID 10322407 DOI: 10.1016/S1043-2760(98)00126-X  0.396
1999 Ma J, Pollak MN, Giovannucci E, Chan JM, Tao Y, Hennekens CH, Stampfer MJ. Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. Journal of the National Cancer Institute. 91: 620-5. PMID 10203281 DOI: 10.1093/jnci/91.7.620  0.331
1999 Nickerson T, Zhang J, Pollak M. Regression of DMBA-induced breast carcinoma following ovariectomy is associated with increased expression of genes encoding insulin-like growth factor binding proteins. International Journal of Oncology. 14: 987-1077. PMID 10200352 DOI: 10.3892/Ijo.14.5.987  0.382
1999 Pollak M. IGF-I physiology and breast cancer. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer. 152: 63-70. PMID 9928547 DOI: 10.1007/978-3-642-45769-2_6  0.399
1999 Toppmeyer D, Seidman A, Overmoyer B, Pollak M, Verma S, Russell C, Tkaczuk K, Prete SD, Schwartz G, Harding MW. A Phase II study of IncelTM (biricodar, VX-710) in combination with paclitaxel in women with advanced breast cancer refractory to paclitaxel European Journal of Cancer. 35. DOI: 10.1016/S0959-8049(99)81708-0  0.324
1998 Burrow S, Andrulis IL, Pollak M, Bell RS. Expression of insulin-like growth factor receptor, IGF-1, and IGF-2 in primary and metastatic osteosarcoma. Journal of Surgical Oncology. 69: 21-7. PMID 9762887 DOI: 10.1002/(Sici)1096-9098(199809)69:1<21::Aid-Jso5>3.0.Co;2-M  0.386
1998 Rozen F, Zhang J, Pollak M. Antiproliferative action of tumor necrosis factor-alpha on MCF-7 breastcancer cells is associated with increased insulin-like growth factor binding protein-3 accumulation. International Journal of Oncology. 13: 865-874. PMID 9735418 DOI: 10.3892/Ijo.13.4.865  0.332
1998 Huynh H, Pollak M, Zhang JC. Regulation of insulin-like growth factor (IGF) II and IGF binding protein 3 autocrine loop in human PC-3 prostate cancer cells by vitamin D metabolite 1,25(OH)2D3 and its analog EB1089 International Journal of Oncology. 13: 137-143. PMID 9625815 DOI: 10.3892/Ijo.13.1.137  0.426
1998 Hankinson SE, Willett WC, Colditz GA, Hunter DJ, Michaud DS, Deroo B, Rosner B, Speizer FE, Pollak M. Circulating concentrations of insulin-like growth factor-I and risk of breast cancer Lancet. 351: 1393-1396. PMID 9593409 DOI: 10.1016/S0140-6736(97)10384-1  0.412
1998 Pollak MN. Endocrine effects of IGF-I on normal and transformed breast epithelial cells: potential relevance to strategies for breast cancer treatment and prevention. Breast Cancer Research and Treatment. 47: 209-17. PMID 9516077 DOI: 10.1023/A:1005950916707  0.326
1998 Nickerson T, Pollak M, Huynh H. Castration-induced apoptosis in the rat ventral prostate is associated with increased expression of genes encoding insulin-like growth factor binding proteins 2,3,4 and 5 Endocrinology. 139: 807-810. PMID 9449659 DOI: 10.1210/Endo.139.2.5912  0.377
1998 Chan J, Stampfer M, Giovannucci E, Gann P, Ma J, Wilkinson P, Hennekens C, Pollak M. Plasma Insulin-Like Growth Factor-I and Prostate Cancer Risk: A Prospective Study Journal of Urology. 160: 267-267. DOI: 10.1126/Science.279.5350.563  0.406
1998 Pollak M. I.4 Effects of anti-oestrogens on insulin-like growth factor (IGF-I) physiology systemically and in the uterus European Journal of Cancer. 34: S11-S12. DOI: 10.1016/S0959-8049(98)00087-2  0.402
1998 Hankinson SE, Willett WC, Speizer FE, Pollak M. Insulin-like growth factor-l and risk of breast cancer The Lancet. 352: 489. DOI: 10.1016/S0140-6736(05)79228-X  0.424
1997 Huynh H, Beamer WD, Pollak M. Overexpression of insulin-like growth factor binding protein 4 (IGFBP-4) in MCF-7 breast cancer cells is associated with reduced responsiveness to insulin-like growth factors in vitro and reduced tumour growth in vivo. International Journal of Oncology. 11: 193-197. PMID 21528201 DOI: 10.3892/Ijo.11.1.193  0.432
1997 Nickerson T, Huynh H, Pollak M. Insulin-like growth factor binding protein-3 induces apoptosis in MCF7 breast cancer cells Biochemical and Biophysical Research Communications. 237: 690-693. PMID 9299428 DOI: 10.1006/Bbrc.1997.7089  0.412
1997 Rozen F, Yang X, Huynh H, Pollak M. Antiproliferative Action of Vitamin D-Related Compounds and Insulin-Like Growth Factor-Binding Protein 5 Accumulation Journal of the National Cancer Institute. 89: 652-656. PMID 9150190 DOI: 10.1093/Jnci/89.9.652  0.384
1996 Pollak M. Enhancement of the Anti-Neoplastic Effects of Tamoxifen by Somatostatin Analogues Digestion. 57: 29-33. PMID 8813463 DOI: 10.1159/000201389  0.353
1996 Pollak M. Peptide growth factors and breast cancer treatment: recent translational research. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer. 140: 43-9. PMID 8787075 DOI: 10.1007/978-3-642-79278-6_6  0.344
1996 Huynh H, Yang X, Pollak M. Estradiol and antiestrogens regulate a growth inhibitory insulin-like growth factor binding protein 3 autocrine loop in human breast cancer cells Journal of Biological Chemistry. 271: 1016-1021. PMID 8557625 DOI: 10.1074/Jbc.271.2.1016  0.421
1995 Hung H, Pollak M. Regulation of IGFBP-3 expression in breast cancer cells and uterus by estradiol and antiestrogens: Correlations with effects on proliferation: A review Progress in Growth Factor Research. 6: 495-501. PMID 8817694 DOI: 10.1016/0955-2235(95)00036-4  0.411
1995 Rosenberg L, Barkun AN, Denis MH, Pollak M. Low dose octreotide and tamoxifen in the treatment of adenocarcinoma of the pancreas. Cancer. 75: 23-8. PMID 7804972 DOI: 10.1002/1097-0142(19950101)75:1<23::Aid-Cncr2820750106>3.0.Co;2-A  0.314
1995 Pollak M. Re: Reversal by Transferrin of Growth-Inhibitory Effect of Suramin on Hormone-Refractory Human Prostate Cancer Cells Journal of the National Cancer Institute. 87: 608-608. PMID 7752260 DOI: 10.1093/Jnci/87.8.608  0.384
1995 Pollak M. Re: Potential impact of genetic testing on cancer prevention trials, using breast cancer as an example. Journal of the National Cancer Institute. 87: 1557-1557. PMID 7563192 DOI: 10.1093/Jnci/87.20.1557  0.354
1994 Sekyi-Otu A, Bell R, Andrulis I, Pollak M. Metastatic behavior of the RIF-1 murine fibrosarcoma: inhibited by hypophysectomy and partially restored by growth hormone replacement. Journal of the National Cancer Institute. 86: 628-32. PMID 8145278 DOI: 10.1093/Jnci/86.8.628  0.362
1994 Huynh H, Pollak M. Enhancement of tamoxifen-induced suppression of insulin-like growth factor I gene expression and serum level by a somatostatin analogue Biochemical and Biophysical Research Communications. 203: 253-259. PMID 8074663 DOI: 10.1006/Bbrc.1994.2175  0.326
1994 Arbour L, Narod S, Glendon G, Pollak M, Seymour R, Miner L, Leung P. In-vitro fertilisation and family history of breast cancer The Lancet. 344: 610-611. PMID 7914975 DOI: 10.1016/S0140-6736(94)91994-1  0.324
1993 Friedl A, Jordan VC, Pollak M. Suppression of serum insulin-like growth factor-1 levels in breast cancer patients during adjuvant tamoxifen therapy. European Journal of Cancer (Oxford, England : 1990). 29: 1368-72. PMID 8398260 DOI: 10.1016/0959-8049(93)90003-X  0.381
1993 Tonin P, Ehrenborg E, Lenoir G, Feunteun J, Lynch H, Morgan K, Zazzi H, Vivier A, Pollak M, Huynh H, Luthman H, Larsson C, Narod S. The Human Insulin-like Growth Factor-Binding Protein 4 Gene Maps to Chromosome Region 17q12-q21.1 and Is Close to the Gene for Hereditary Breast-Ovarian Cancer Genomics. 18: 414-417. PMID 7507078 DOI: 10.1006/Geno.1993.1487  0.352
1992 Pollak MN, Huynh HT, Lefebvre SP. Tamoxifen reduces serum insulin-like growth factor I (IGF-I). Breast Cancer Research and Treatment. 22: 91-100. PMID 1421427 DOI: 10.1007/BF01833337  0.317
1992 Pollak M, Gallant K, Poisson R, Harris A. Potential role for somatostatin analogues in breast cancer: rationale and description of an ongoing trial. Metabolism-Clinical and Experimental. 41: 119-120. PMID 1355585 DOI: 10.1016/0026-0495(92)90045-C  0.36
1992 Tannenbaum GS, Gurd W, Lapointe M, Pollak M. Tamoxifen attenuates pulsatile growth hormone secretion: mediation in part by somatostatin. Endocrinology. 130: 3395-401. PMID 1350760 DOI: 10.1210/Endo.130.6.1350760  0.334
1992 Pollak M, Sem AW, Richard M, Tetenes E, Bell R. Inhibition of metastatic behavior of murine osteosarcoma by hypophysectomy. Journal of the National Cancer Institute. 84: 966-71. PMID 1321252 DOI: 10.1093/Jnci/84.12.966  0.339
1991 Pollak M, Boyarsky A, Gora P. A mathematical model describing consequences of abnormally high levels of epidermal growth factor receptor on the proliferation of neoplastic cells. Cancer Investigation. 9: 513-20. PMID 1933484 DOI: 10.3109/07357909109018949  0.304
1991 Dawson NA, Costanza ME, Korzun AH, Clamon GH, Pollak M, Vogelzang NJ, Carey RW, Norton L. Trimetrexate in untreated and previously treated patients with metastatic breast cancer: a Cancer and Leukemia Group B study. Medical and Pediatric Oncology. 19: 283-8. PMID 1829134 DOI: 10.1002/Mpo.2950190413  0.338
1990 Pollak M, Costantino J, Polychronakos C, Blauer SA, Guyda H, Redmond C, Fisher B, Margolese R. Effect of tamoxifen on serum insulinlike growth factor I levels in stage I breast cancer patients Journal of the National Cancer Institute. 82: 1693-1697. PMID 2231756 DOI: 10.1093/Jnci/82.21.1693  0.434
1990 Pollak M, Richard M. Suramin blockade of insulinlike growth factor I-stimulated proliferation of human osteosarcoma cells. Journal of the National Cancer Institute. 82: 1349-52. PMID 2166171 DOI: 10.1093/Jnci/82.16.1349  0.353
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