Chinnaswamy Tiruppathi - Publications

Affiliations: 
University of Illinois at Chicago, Health Sciences Center, Chicago, IL 60612, United States 
Area:
Pharmacology, Cell Biology

80 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mukhopadhyay A, Tsukasaki Y, Chan WC, Le JP, Kwok ML, Zhou J, Natarajan V, Mostafazadeh N, Maienschein-Cline M, Papautsky I, Tiruppathi C, Peng Z, Rehman J, Ganesh B, Komarova Y, et al. trans-Endothelial neutrophil migration activates bactericidal function via Piezo1 mechanosensing. Immunity. PMID 38091995 DOI: 10.1016/j.immuni.2023.11.007  0.345
2023 Tiruppathi C, Wang DM, Ansari MO, Bano S, Tsukasaki Y, Mukhopadhyay A, Joshi JC, Loch C, Niessen HWM, Malik AB. Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions. Nature Communications. 14: 6582. PMID 37852964 DOI: 10.1038/s41467-023-42225-2  0.389
2022 Wang DM, Soni D, Regmi SC, Vogel SM, Tiruppathi C. TAK1 is essential for endothelial barrier maintenance and repair after lung vascular injury. Molecular Biology of the Cell. mbcE21110563. PMID 35324316 DOI: 10.1091/mbc.E21-11-0563  0.353
2020 Tiruppathi C, Regmi SC, Wang DM, Mo GCH, Toth PT, Vogel SM, Stan RV, Henkemeyer M, Minshall RD, Rehman J, Malik AB. EphB1 Interaction with Caveolin-1 in Endothelial Cells Modulates Caveolae Biogenesis. Molecular Biology of the Cell. mbcE19120713. PMID 32238105 DOI: 10.1091/Mbc.E19-12-0713  0.502
2019 Nepal S, Tiruppathi C, Tsukasaki Y, Farahany J, Mittal M, Rehman J, Prockop DJ, Malik AB. STAT6 induces expression of Gas6 in macrophages to clear apoptotic neutrophils and resolve inflammation. Proceedings of the National Academy of Sciences of the United States of America. PMID 31363052 DOI: 10.1073/Pnas.1821601116  0.345
2018 Soni D, Wang DM, Regmi SC, Mittal M, Vogel SM, Schlüter D, Tiruppathi C. Deubiquitinase function of A20 maintains and repairs endothelial barrier after lung vascular injury. Cell Death Discovery. 4: 60. PMID 29796309 DOI: 10.1038/S41420-018-0056-3  0.405
2018 Soni D, Wang D, Regmi SC, Vogel SM, Schlüter D, Tiruppathi C. DUB activity of Endothelial A20 maintains and repairs endothelial barrier after inflammatory lung injury F1000research. 7. DOI: 10.7490/F1000Research.1116279.1  0.343
2017 Mittal M, Nepal S, Tsukasaki Y, Hecquet CM, Soni D, Tiruppathi C, Malik AB, Rehman J. Response by Mittal et al to Letter Regarding Article, "Neutrophil Activation of Endothelial Cell-Expressed TRPM2 Mediates Transendothelial Neutrophil Migration and Vascular Injury". Circulation Research. 121: e87. PMID 29217714 DOI: 10.1161/Circresaha.117.312146  0.458
2017 Mittal M, Nepal S, Tsukasaki Y, Hecquet CM, Soni D, Rehman J, Tiruppathi C, Malik AB. Neutrophil Activation of Endothelial Cell-Expressed TRPM2 Mediates Transendothelial Neutrophil Migration and Vascular Injury. Circulation Research. PMID 28790198 DOI: 10.1161/Circresaha.117.311747  0.604
2017 Soni D, Regmi SC, Wang DM, DebRoy A, Zhao YY, Vogel SM, Malik AB, Tiruppathi C. Pyk2 Phosphorylation of VE-PTP Downstream of STIM1 induced Ca2+ entry Regulates Disassembly of Adherens Junctions. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00008.2017. PMID 28385807 DOI: 10.1152/Ajplung.00008.2017  0.59
2017 Marsboom G, Chen Z, Yuan Y, Zhang Y, Tiruppathi C, Loyd JE, Austin ED, Machado RF, Minshall RD, Rehman J, Malik AB. Aberrant Caveolin-1-Mediated Smad Signaling and Proliferation Identified by Analysis of Adenine 474 Deletion Mutation (c.474delA) in Patient Fibroblasts: A New Perspective in the Mechanism of Pulmonary Hypertension. Molecular Biology of the Cell. PMID 28298490 DOI: 10.1091/Mbc.E16-06-0380  0.309
2017 Ayee MA, LeMaster E, Shentu TP, Singh DK, Barbera N, Soni D, Tiruppathi C, Subbaiah PV, Berdyshev E, Bronova I, Cho M, Akpa BS, Levitan I. Molecular-Scale Biophysical Modulation of an Endothelial Membrane by Oxidized Phospholipids. Biophysical Journal. 112: 325-338. PMID 28122218 DOI: 10.1016/J.Bpj.2016.12.002  0.314
2016 Mittal M, Tiruppathi C, Nepal S, Zhao YY, Grzych D, Soni D, Prockop DJ, Malik AB. TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911817 DOI: 10.1073/Pnas.1614935113  0.344
2016 Wang G, Cao L, Liu X, Sieracki NA, Di A, Wen X, Chen Y, Taylor S, Huang X, Tiruppathi C, Zhao YY, Song Y, Gao X, Jin T, Bai C, et al. Oxidant Sensing by TRPM2 Inhibits Neutrophil Migration and Mitigates Inflammation. Developmental Cell. PMID 27569419 DOI: 10.1016/J.Devcel.2016.07.014  0.336
2016 Zimnicka AM, Husain YS, Shajahan AN, Sverdlov M, Chaga O, Chen Z, Toth PT, Klomp J, Karginov AV, Tiruppathi C, Malik AB, Minshall RD. Src-dependent phosphorylation of caveolin-1 Tyr14 promotes swelling and release of caveolae. Molecular Biology of the Cell. PMID 27170175 DOI: 10.1091/Mbc.E15-11-0756  0.437
2015 Barazia A, Li J, Kim K, Tiruppathi C, Cho J. Neutrophil DREAM Is a Novel Regulator for Beta2 Integrin Function through NF-Kappab Signaling and Modulates Neutrophil Recruitment during Vascular Inflammation Blood. 126: 888-888. DOI: 10.1182/Blood.V126.23.888.888  0.445
2014 DebRoy A, Vogel SM, Soni D, Sundivakkam PC, Malik AB, Tiruppathi C. Cooperative signaling via transcription factors NF-κB and AP1/c-Fos mediates endothelial cell STIM1 expression and hyperpermeability in response to endotoxin. The Journal of Biological Chemistry. 289: 24188-201. PMID 25016017 DOI: 10.1074/Jbc.M114.570051  0.475
2014 Zhao YD, Huang X, Yi F, Dai Z, Qian Z, Tiruppathi C, Tran K, Zhao YY. Endothelial FoxM1 mediates bone marrow progenitor cell-induced vascular repair and resolution of inflammation following inflammatory lung injury. Stem Cells (Dayton, Ohio). 32: 1855-64. PMID 24578354 DOI: 10.1002/Stem.1690  0.436
2014 Tiruppathi C, Soni D, Wang DM, Xue J, Singh V, Thippegowda PB, Cheppudira BP, Mishra RK, Debroy A, Qian Z, Bachmaier K, Zhao YY, Christman JW, Vogel SM, Ma A, et al. The transcription factor DREAM represses the deubiquitinase A20 and mediates inflammation. Nature Immunology. 15: 239-47. PMID 24487321 DOI: 10.1038/Ni.2823  0.329
2014 Kim K, Barazia A, Tseng A, Tiruppathi C, Italiano JE, Cho J. DREAM, a Transcription Repressor, Is Critical for Calcium Signaling and Platelet Thrombus Formation Independently of Its Transcriptional Activity Blood. 124: 338-338. DOI: 10.1182/Blood.V124.21.338.338  0.419
2013 Sundivakkam PC, Natarajan V, Malik AB, Tiruppathi C. Store-operated Ca2+ entry (SOCE) induced by protease-activated receptor-1 mediates STIM1 protein phosphorylation to inhibit SOCE in endothelial cells through AMP-activated protein kinase and p38β mitogen-activated protein kinase. The Journal of Biological Chemistry. 288: 17030-41. PMID 23625915 DOI: 10.1074/Jbc.M112.411272  0.536
2013 Fu P, Mohan V, Mansoor S, Tiruppathi C, Sadikot RT, Natarajan V. Role of nicotinamide adenine dinucleotide phosphate-reduced oxidase proteins in Pseudomonas aeruginosa-induced lung inflammation and permeability. American Journal of Respiratory Cell and Molecular Biology. 48: 477-88. PMID 23306835 DOI: 10.1165/Rcmb.2012-0242Oc  0.376
2012 Ravindran S, Gao Q, Ramachandran A, Sundivakkam P, Tiruppathi C, George A. Expression and distribution of grp-78/bip in mineralizing tissues and mesenchymal cells. Histochemistry and Cell Biology. 138: 113-25. PMID 22527697 DOI: 10.1007/S00418-012-0952-1  0.362
2012 Sundivakkam PC, Freichel M, Singh V, Yuan JP, Vogel SM, Flockerzi V, Malik AB, Tiruppathi C. The Ca(2+) sensor stromal interaction molecule 1 (STIM1) is necessary and sufficient for the store-operated Ca(2+) entry function of transient receptor potential canonical (TRPC) 1 and 4 channels in endothelial cells. Molecular Pharmacology. 81: 510-26. PMID 22210847 DOI: 10.1124/Mol.111.074658  0.543
2011 Wang Z, Tiruppathi C, Cho J, Minshall RD, Malik AB. Delivery of nanoparticle: complexed drugs across the vascular endothelial barrier via caveolae. Iubmb Life. 63: 659-67. PMID 21766412 DOI: 10.1002/Iub.485  0.346
2011 Mehta RR, Yamada T, Taylor BN, Christov K, King ML, Majumdar D, Lekmine F, Tiruppathi C, Shilkaitis A, Bratescu L, Green A, Beattie CW, Das Gupta TK. A cell penetrating peptide derived from azurin inhibits angiogenesis and tumor growth by inhibiting phosphorylation of VEGFR-2, FAK and Akt. Angiogenesis. 14: 355-69. PMID 21667138 DOI: 10.1007/S10456-011-9220-6  0.353
2011 Ahmmed GU, Mehta D, Vogel S, Holinstat M, Paria BC, Tiruppathi C, Malik AB. Protein kinase Cα phosphorylates the TRPC1 channel and regulates store-operated Ca2+entry in endothelial cells. Journal of Biological Chemistry. 286: 36162-36162. DOI: 10.1074/Jbc.A111.313975  0.507
2010 Minshall RD, Vandenbroucke EE, Holinstat M, Place AT, Tiruppathi C, Vogel SM, van Nieuw Amerongen GP, Mehta D, Malik AB. Role of protein kinase Czeta in thrombin-induced RhoA activation and inter-endothelial gap formation of human dermal microvessel endothelial cell monolayers. Microvascular Research. 80: 240-9. PMID 20417648 DOI: 10.1016/J.Mvr.2010.04.007  0.625
2010 Mirza MK, Yuan J, Gao XP, Garrean S, Brovkovych V, Malik AB, Tiruppathi C, Zhao YY. Caveolin-1 deficiency dampens Toll-like receptor 4 signaling through eNOS activation. The American Journal of Pathology. 176: 2344-51. PMID 20304961 DOI: 10.2353/Ajpath.2010.091088  0.464
2010 Thippegowda PB, Singh V, Sundivakkam PC, Xue J, Malik AB, Tiruppathi C. Ca2+ influx via TRPC channels induces NF-kappaB-dependent A20 expression to prevent thrombin-induced apoptosis in endothelial cells. American Journal of Physiology. Cell Physiology. 298: C656-64. PMID 20032510 DOI: 10.1152/Ajpcell.00456.2009  0.52
2009 Wang Z, Tiruppathi C, Minshall RD, Malik AB. Size and dynamics of caveolae studied using nanoparticles in living endothelial cells. Acs Nano. 3: 4110-6. PMID 19919048 DOI: 10.1021/Nn9012274  0.33
2009 Xue J, Thippegowda PB, Hu G, Bachmaier K, Christman JW, Malik AB, Tiruppathi C. NF-kappaB regulates thrombin-induced ICAM-1 gene expression in cooperation with NFAT by binding to the intronic NF-kappaB site in the ICAM-1 gene. Physiological Genomics. 38: 42-53. PMID 19351910 DOI: 10.1152/Physiolgenomics.00012.2009  0.438
2009 Sundivakkam PC, Kwiatek AM, Sharma TT, Minshall RD, Malik AB, Tiruppathi C. Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store release-induced Ca2+ entry in endothelial cells. American Journal of Physiology. Cell Physiology. 296: C403-13. PMID 19052258 DOI: 10.1152/Ajpcell.00470.2008  0.8
2009 Bair AM, Thippegowda PB, Freichel M, Cheng N, Ye RD, Vogel SM, Yu Y, Flockerzi V, Malik AB, Tiruppathi C. Ca2+ entry via TRPC channels is necessary for thrombin-induced NF-kappaB activation in endothelial cells through AMP-activated protein kinase and protein kinase Cdelta. The Journal of Biological Chemistry. 284: 563-74. PMID 18990707 DOI: 10.1074/Jbc.M803984200  0.829
2009 Welch EJ, Naikawadi RP, Li Z, Lin P, Ishii S, Shimizu T, Tiruppathi C, Du X, Subbaiah PV, Ye RD. Opposing effects of platelet-activating factor and lyso-platelet-activating factor on neutrophil and platelet activation. Molecular Pharmacology. 75: 227-34. PMID 18931035 DOI: 10.1124/Mol.108.051003  0.374
2008 Khasawneh FT, Huang JS, Mir F, Srinivasan S, Tiruppathi C, Le Breton GC. Characterization of isoprostane signaling: evidence for a unique coordination profile of 8-iso-PGF(2alpha) with the thromboxane A(2) receptor, and activation of a separate cAMP-dependent inhibitory pathway in human platelets. Biochemical Pharmacology. 75: 2301-15. PMID 18455148 DOI: 10.1016/J.Bcp.2008.03.014  0.351
2008 Tiruppathi C, Shimizu J, Miyawaki-Shimizu K, Vogel SM, Bair AM, Minshall RD, Predescu D, Malik AB. Role of NF-kappaB-dependent caveolin-1 expression in the mechanism of increased endothelial permeability induced by lipopolysaccharide. The Journal of Biological Chemistry. 283: 4210-8. PMID 18077459 DOI: 10.1074/Jbc.M703153200  0.787
2007 Bachmaier K, Toya S, Gao X, Triantafillou T, Garrean S, Park GY, Frey RS, Vogel S, Minshall R, Christman JW, Tiruppathi C, Malik AB. E3 ubiquitin ligase Cblb regulates the acute inflammatory response underlying lung injury. Nature Medicine. 13: 920-6. PMID 17618294 DOI: 10.1038/Nm1607  0.366
2006 Tiruppathi C, Ahmmed GU, Vogel SM, Malik AB. Ca2+ signaling, TRP channels, and endothelial permeability. Microcirculation (New York, N.Y. : 1994). 13: 693-708. PMID 17085428 DOI: 10.1080/10739680600930347  0.629
2006 Maniatis NA, Brovkovych V, Allen SE, John TA, Shajahan AN, Tiruppathi C, Vogel SM, Skidgel RA, Malik AB, Minshall RD. Novel mechanism of endothelial nitric oxide synthase activation mediated by caveolae internalization in endothelial cells. Circulation Research. 99: 870-7. PMID 16973909 DOI: 10.1161/01.Res.0000245187.08026.47  0.505
2006 Kwiatek AM, Minshall RD, Cool DR, Skidgel RA, Malik AB, Tiruppathi C. Caveolin-1 regulates store-operated Ca2+ influx by binding of its scaffolding domain to transient receptor potential channel-1 in endothelial cells. Molecular Pharmacology. 70: 1174-83. PMID 16822931 DOI: 10.1124/Mol.105.021741  0.791
2006 Paria BC, Bair AM, Xue J, Yu Y, Malik AB, Tiruppathi C. Ca2+ influx induced by protease-activated receptor-1 activates a feed-forward mechanism of TRPC1 expression via nuclear factor-kappaB activation in endothelial cells. The Journal of Biological Chemistry. 281: 20715-27. PMID 16709572 DOI: 10.1074/Jbc.M600722200  0.838
2005 Jho D, Mehta D, Ahmmed G, Gao XP, Tiruppathi C, Broman M, Malik AB. Angiopoietin-1 opposes VEGF-induced increase in endothelial permeability by inhibiting TRPC1-dependent Ca2 influx. Circulation Research. 96: 1282-90. PMID 15920022 DOI: 10.1161/01.Res.0000171894.03801.03  0.58
2004 Paria BC, Vogel SM, Ahmmed GU, Alamgir S, Shroff J, Malik AB, Tiruppathi C. Tumor necrosis factor-alpha-induced TRPC1 expression amplifies store-operated Ca2+ influx and endothelial permeability. American Journal of Physiology. Lung Cellular and Molecular Physiology. 287: L1303-13. PMID 15347566 DOI: 10.1152/Ajplung.00240.2004  0.612
2004 Shajahan AN, Tiruppathi C, Smrcka AV, Malik AB, Minshall RD. Gbetagamma activation of Src induces caveolae-mediated endocytosis in endothelial cells. The Journal of Biological Chemistry. 279: 48055-62. PMID 15345719 DOI: 10.1074/Jbc.M405837200  0.517
2004 Tiruppathi C, Naqvi T, Wu Y, Vogel SM, Minshall RD, Malik AB. Albumin mediates the transcytosis of myeloperoxidase by means of caveolae in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 7699-704. PMID 15136724 DOI: 10.1073/Pnas.0401712101  0.429
2004 Ahmmed GU, Mehta D, Vogel S, Holinstat M, Paria BC, Tiruppathi C, Malik AB. Protein kinase Calpha phosphorylates the TRPC1 channel and regulates store-operated Ca2+ entry in endothelial cells. The Journal of Biological Chemistry. 279: 20941-9. PMID 15016832 DOI: 10.1074/Jbc.M313975200  0.584
2004 Shajahan AN, Timblin BK, Sandoval R, Tiruppathi C, Malik AB, Minshall RD. Role of Src-induced dynamin-2 phosphorylation in caveolae-mediated endocytosis in endothelial cells. The Journal of Biological Chemistry. 279: 20392-400. PMID 15007081 DOI: 10.1074/Jbc.M308710200  0.776
2003 Paria BC, Malik AB, Kwiatek AM, Rahman A, May MJ, Ghosh S, Tiruppathi C. Tumor necrosis factor-alpha induces nuclear factor-kappaB-dependent TRPC1 expression in endothelial cells. The Journal of Biological Chemistry. 278: 37195-203. PMID 12855710 DOI: 10.1074/Jbc.M304287200  0.801
2003 Mehta D, Ahmmed GU, Paria BC, Holinstat M, Voyno-Yasenetskaya T, Tiruppathi C, Minshall RD, Malik AB. RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability. The Journal of Biological Chemistry. 278: 33492-500. PMID 12766172 DOI: 10.1074/Jbc.M302401200  0.608
2003 John TA, Vogel SM, Tiruppathi C, Malik AB, Minshall RD. Quantitative analysis of albumin uptake and transport in the rat microvessel endothelial monolayer. American Journal of Physiology. Lung Cellular and Molecular Physiology. 284: L187-96. PMID 12471015 DOI: 10.1152/Ajplung.00152.2002  0.326
2002 Tiruppathi C, Minshall RD, Paria BC, Vogel SM, Malik AB. Role of Ca2+ signaling in the regulation of endothelial permeability. Vascular Pharmacology. 39: 173-85. PMID 12747958 DOI: 10.1016/S1537-1891(03)00007-7  0.614
2002 Tiruppathi C, Freichel M, Vogel SM, Paria BC, Mehta D, Flockerzi V, Malik AB. Impairment of store-operated Ca2+ entry in TRPC4(-/-) mice interferes with increase in lung microvascular permeability. Circulation Research. 91: 70-6. PMID 12114324 DOI: 10.1161/01.Res.0000023391.40106.A8  0.578
2002 Vanhauwe JF, Thomas TO, Minshall RD, Tiruppathi C, Li A, Gilchrist A, Yoon EJ, Malik AB, Hamm HE. Thrombin receptors activate G(o) proteins in endothelial cells to regulate intracellular calcium and cell shape changes. The Journal of Biological Chemistry. 277: 34143-9. PMID 12039967 DOI: 10.1074/Jbc.M204477200  0.355
2002 Minshall RD, Tiruppathi C, Vogel SM, Malik AB. Vesicle formation and trafficking in endothelial cells and regulation of endothelial barrier function. Histochemistry and Cell Biology. 117: 105-12. PMID 11935286 DOI: 10.1007/S00418-001-0367-X  0.445
2002 Mehta D, Tiruppathi C, Sandoval R, Minshall RD, Holinstat M, Malik AB. Modulatory role of focal adhesion kinase in regulating human pulmonary arterial endothelial barrier function. The Journal of Physiology. 539: 779-89. PMID 11897849 DOI: 10.1113/Jphysiol.2001.013289  0.8
2002 Vogel SM, Minshall RD, Pilipović M, Tiruppathi C, Malik AB. Albumin uptake and transcytosis in endothelial cells in vivo induced by albumin-binding protein. American Journal of Physiology. Lung Cellular and Molecular Physiology. 281: L1512-22. PMID 11704548 DOI: 10.1152/Ajplung.2001.281.6.L1512  0.371
2001 Tiruppathi C, Naqvi T, Sandoval R, Mehta D, Malik AB. Synergistic effects of tumor necrosis factor-alpha and thrombin in increasing endothelial permeability. American Journal of Physiology. Lung Cellular and Molecular Physiology. 281: L958-68. PMID 11557600 DOI: 10.1152/Ajplung.2001.281.4.L958  0.804
2001 Sandoval R, Malik AB, Minshall RD, Kouklis P, Ellis CA, Tiruppathi C. Ca(2+) signalling and PKCalpha activate increased endothelial permeability by disassembly of VE-cadherin junctions. The Journal of Physiology. 533: 433-45. PMID 11389203 DOI: 10.1111/J.1469-7793.2001.0433A.X  0.817
2001 Vogel SM, Easington CR, Minshall RD, Niles WD, Tiruppathi C, Hollenberg SM, Parrillo JE, Malik AB. Evidence of transcellular permeability pathway in microvessels. Microvascular Research. 61: 87-101. PMID 11162199 DOI: 10.1006/Mvre.2000.2274  0.349
2001 Sandoval R, Malik AB, Naqvi T, Mehta D, Tiruppathi C. Requirement for Ca2+ signaling in the mechanism of thrombin-induced increase in endothelial permeability. American Journal of Physiology. Lung Cellular and Molecular Physiology. 280: L239-47. PMID 11159002 DOI: 10.1152/Ajplung.2001.280.2.L239  0.826
2000 Vogel SM, Gao X, Mehta D, Ye RD, John TA, Andrade-Gordon P, Tiruppathi C, Malik AB. Abrogation of thrombin-induced increase in pulmonary microvascular permeability in PAR-1 knockout mice. Physiological Genomics. 4: 137-145. PMID 11120874 DOI: 10.1152/Physiolgenomics.2000.4.2.137  0.327
2000 Minshall RD, Tiruppathi C, Vogel SM, Niles WD, Gilchrist A, Hamm HE, Malik AB. Endothelial cell-surface gp60 activates vesicle formation and trafficking via G(i)-coupled Src kinase signaling pathway. The Journal of Cell Biology. 150: 1057-70. PMID 10973995 DOI: 10.1083/Jcb.150.5.1057  0.4
2000 Xu N, Rahman A, Minshall RD, Tiruppathi C, Malik AB. beta(2)-Integrin blockade driven by E-selectin promoter prevents neutrophil sequestration and lung injury in mice. Circulation Research. 87: 254-60. PMID 10926878 DOI: 10.1161/01.Res.87.3.254  0.478
2000 Tiruppathi C, Yan W, Sandoval R, Naqvi T, Pronin AN, Benovic JL, Malik AB. G protein-coupled receptor kinase-5 regulates thrombin-activated signaling in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 7440-5. PMID 10861009 DOI: 10.1073/Pnas.97.13.7440  0.829
2000 Dulin NO, Pratt P, Tiruppathi C, Niu J, Voyno-Yasenetskaya T, Dunn MJ. Regulator of G protein signaling RGS3T is localized to the nucleus and induces apoptosis. The Journal of Biological Chemistry. 275: 21317-23. PMID 10749886 DOI: 10.1074/Jbc.M910079199  0.389
2000 Thomas TO, Gilchrist A, Li A, Vanhauwe JF, Voyno-Yasenetskaya TA, Tiruppathi C, Hamm HE. Systematic study of dominant negative Gα C-terminal minigenes delineate G protein pathways in thrombin-mediated responses of endothelial cells Biochemical Society Transactions. 28: A470-A470. DOI: 10.1042/Bst028A470A  0.398
1999 Ellis CA, Tiruppathi C, Sandoval R, Niles WD, Malik AB. Time course of recovery of endothelial cell surface thrombin receptor (PAR-1) expression. American Journal of Physiology. Cell Physiology. 276: C38-C45. PMID 29590789 DOI: 10.1152/ajpcell.1999.276.1.C38  0.781
1999 Ellis CA, Malik AB, Gilchrist A, Hamm H, Sandoval R, Voyno-Yasenetskaya T, Tiruppathi C. Thrombin induces proteinase-activated receptor-1 gene expression in endothelial cells via activation of Gi-linked Ras/mitogen-activated protein kinase pathway. The Journal of Biological Chemistry. 274: 13718-27. PMID 10224146 DOI: 10.1074/Jbc.274.19.13718  0.78
1999 Ellis CA, Tiruppathi C, Sandoval R, Niles WD, Malik AB. Time course of recovery of endothelial cell surface thrombin receptor (PAR-1) expression. The American Journal of Physiology. 276: C38-45. PMID 9886918 DOI: 10.1152/Ajpcell.1999.276.1.C38  0.788
1998 Yan W, Tiruppathi C, Lum H, Qiao R, Malik AB. Protein kinase Cβ regulates heterologous desensitization of thrombin receptor (PAR-1) in endothelial cells. American Journal of Physiology. Cell Physiology. 274: C387-C395. PMID 29590937 DOI: 10.1152/Ajpcell.1998.274.2.C387  0.538
1998 Zhou MY, Lo SK, Bergenfeldt M, Tiruppathi C, Jaffe A, Xu N, Malik AB. In vivo expression of neutrophil inhibitory factor via gene transfer prevents lipopolysaccharide-induced lung neutrophil infiltration and injury by a beta2 integrin-dependent mechanism. The Journal of Clinical Investigation. 101: 2427-37. PMID 9616214 DOI: 10.1172/Jci407  0.429
1997 Nguyen LT, Lum H, Tiruppathì C, Malik AB. Site-specific thrombin receptor antibodies inhibit Casignaling and increased endothelial permeability. American Journal of Physiology. Cell Physiology. 273: C1756-C1763. PMID 29585038 DOI: 10.1152/Ajpcell.1997.273.5.C1756  0.399
1997 Tiruppathi C, Song W, Bergenfeldt M, Sass P, Malik AB. Gp60 activation mediates albumin transcytosis in endothelial cells by tyrosine kinase-dependent pathway. The Journal of Biological Chemistry. 272: 25968-75. PMID 9325331 DOI: 10.1074/Jbc.272.41.25968  0.418
1996 Yan W, Tiruppathi C, Qiao R, Lum H, Malik AB. Tumor necrosis factor decreases thrombin receptor expression in endothelial cells. Journal of Cellular Physiology. 166: 561-7. PMID 8600159 DOI: 10.1002/(Sici)1097-4652(199603)166:3<561::Aid-Jcp10>3.0.Co;2-A  0.469
1996 Tiruppathi C, Finnegan A, Malik AB. Isolation and characterization of a cell surface albumin-binding protein from vascular endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 250-4. PMID 8552615 DOI: 10.1073/Pnas.93.1.250  0.317
1993 Lum H, Andersen TT, Siflinger-Birnboim A, Tiruppathi C, Goligorsky MS, Fenton JW, Malik AB. Thrombin receptor peptide inhibits thrombin-induced increase in endothelial permeability by receptor desensitization. The Journal of Cell Biology. 120: 1491-9. PMID 8383691 DOI: 10.1083/Jcb.120.6.1491  0.504
1992 Tiruppathi C, Malik AB, Del Vecchio PJ, Keese CR, Giaever I. Electrical method for detection of endothelial cell shape change in real time: assessment of endothelial barrier function. Proceedings of the National Academy of Sciences of the United States of America. 89: 7919-23. PMID 1518814 DOI: 10.1073/Pnas.89.17.7919  0.4
1992 Sugama Y, Tiruppathi C, Janakidevi K, Andersen TT, Fenton JW, Malik AB. Thrombin-induced expression of endothelial P-selectin and intercellular adhesion molecule-1: A mechanism for stabilizing neutrophil adhesion Journal of Cell Biology. 119: 935-944. PMID 1385447 DOI: 10.1083/Jcb.119.4.935  0.38
1992 Tiruppathi C, Lum H, Andersen TT, Fenton JW, Malik AB. Thrombin receptor 14-amino acid peptide binds to endothelial cells and stimulates calcium transients American Journal of Physiology - Lung Cellular and Molecular Physiology. 263. PMID 1332502 DOI: 10.1152/Ajplung.1992.263.5.L595  0.45
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