| Year |
Citation |
Score |
| 2020 |
Shiffka SJ, Jones J, Li L, Farese AM, MacVittie TJ, Wang H, Swaan PW, Kane MA. Quantification of common and planar bile acids aids in tissues and cultured cells. Journal of Lipid Research. PMID 32718973 DOI: 10.1194/Jlr.D120000726 |
0.308 |
|
| 2019 |
Li L, Welch MA, Li Z, Mackowiak B, Heyward S, Swaan PW, Wang H. Mechanistic Insights of Phenobarbital-Mediated Activation of Human but Not Mouse Pregnane X Receptor. Molecular Pharmacology. 96: 345-354. PMID 31436536 DOI: 10.1124/Mol.119.116616 |
0.366 |
|
| 2019 |
Chothe PP, Czuba LC, Ayewoh EN, Swaan PW. Tyrosine phosphorylation regulates plasma membrane expression and stability of the human bile acid transporter ASBT (SLC10A2). Molecular Pharmaceutics. PMID 31194565 DOI: 10.1021/Acs.Molpharmaceut.9B00426 |
0.348 |
|
| 2018 |
Schlessinger A, Welch MA, van Vlijmen H, Korzekwa K, Swaan PW, Matsson P. Molecular Modeling of Drug-Transporter Interactions-an International Transporter Consortium Perspective. Clinical Pharmacology and Therapeutics. PMID 29981151 DOI: 10.1002/Cpt.1174 |
0.418 |
|
| 2018 |
Czuba LC, Hillgren KM, Swaan PW. Post-translational modifications of transporters. Pharmacology & Therapeutics. PMID 29966598 DOI: 10.1016/J.Pharmthera.2018.06.013 |
0.434 |
|
| 2017 |
Chothe PP, Czuba LC, Moore RH, Swaan PW. Human bile acid transporter ASBT (SLC10A2) forms functional non-covalent homodimers and higher order oligomers. Biochimica Et Biophysica Acta. 1860: 645-653. PMID 29198943 DOI: 10.1016/J.Bbamem.2017.11.016 |
0.365 |
|
| 2017 |
Mackowiak B, Li L, Welch MA, Li D, Jones JW, Heyward S, Kane MA, Swaan PW, Wang H. Molecular basis of metabolism-mediated conversion of PK11195 from an antagonist to an agonist of the constitutive androstane receptor. Molecular Pharmacology. PMID 28442602 DOI: 10.1124/Mol.117.108621 |
0.366 |
|
| 2017 |
Ali I, Welch MA, Lu Y, Swaan PW, Brouwer KL. Identification of novel MRP3 inhibitors based on computational models and validation using an in vitro membrane vesicle assay. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 28238947 DOI: 10.1016/J.Ejps.2017.02.011 |
0.374 |
|
| 2015 |
Duan H, Hu T, Foti RS, Pan Y, Swaan PW, Wang J. Potent and Selective Inhibition of Plasma Membrane Monoamine Transporter by HIV Protease Inhibitors. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 1773-80. PMID 26285765 DOI: 10.1124/Dmd.115.064824 |
0.379 |
|
| 2015 |
Avaritt BR, Swaan PW. Internalization and Subcellular Trafficking of Poly-l-lysine Dendrimers Are Impacted by the Site of Fluorophore Conjugation. Molecular Pharmaceutics. 12: 1961-9. PMID 25950742 DOI: 10.1021/Mp500765E |
0.389 |
|
| 2015 |
Welch MA, Köck K, Urban TJ, Brouwer KL, Swaan PW. Toward predicting drug-induced liver injury: parallel computational approaches to identify multidrug resistance protein 4 and bile salt export pump inhibitors. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 725-34. PMID 25735837 DOI: 10.1124/Dmd.114.062539 |
0.353 |
|
| 2014 |
Avaritt BR, Swaan PW. Intracellular Ca2+ release mediates cationic but not anionic poly(amidoamine) (PAMAM) dendrimer-induced tight junction modulation. Pharmaceutical Research. 31: 2429-38. PMID 24648136 DOI: 10.1007/S11095-014-1338-Y |
0.37 |
|
| 2014 |
Schuetz JD, Swaan PW, Tweedie DJ. The role of transporters in toxicity and disease Drug Metabolism and Disposition. 42: 541-545. PMID 24598705 DOI: 10.1124/Dmd.114.057539 |
0.405 |
|
| 2014 |
Chothe PP, Swaan PW. Resveratrol promotes degradation of the human bile acid transporter ASBT (SLC10A2). The Biochemical Journal. 459: 301-12. PMID 24498857 DOI: 10.1042/Bj20131428 |
0.352 |
|
| 2014 |
Köck K, Ferslew BC, Netterberg I, Yang K, Urban TJ, Swaan PW, Stewart PW, Brouwer KL. Risk factors for development of cholestatic drug-induced liver injury: inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 665-74. PMID 24154606 DOI: 10.1124/Dmd.113.054304 |
0.374 |
|
| 2013 |
Sabit H, Mallajosyula SS, MacKerell AD, Swaan PW. Transmembrane domain II of the human bile acid transporter SLC10A2 coordinates sodium translocation. The Journal of Biological Chemistry. 288: 32394-404. PMID 24045943 DOI: 10.1074/Jbc.M113.518555 |
0.406 |
|
| 2013 |
Moore RH, Chothe P, Swaan PW. Transmembrane domain V plays a stabilizing role in the function of human bile acid transporter SLC10A2. Biochemistry. 52: 5117-24. PMID 23815591 DOI: 10.1021/Bi400028Q |
0.322 |
|
| 2013 |
Zamek-Gliszczynski MJ, Lee CA, Poirier A, Bentz J, Chu X, Ellens H, Ishikawa T, Jamei M, Kalvass JC, Nagar S, Pang KS, Korzekwa K, Swaan PW, Taub ME, Zhao P, et al. ITC recommendations for transporter kinetic parameter estimation and translational modeling of transport-mediated PK and DDIs in humans. Clinical Pharmacology and Therapeutics. 94: 64-79. PMID 23588311 DOI: 10.1038/Clpt.2013.45 |
0.402 |
|
| 2013 |
Claro da Silva T, Polli JE, Swaan PW. The solute carrier family 10 (SLC10): beyond bile acid transport. Molecular Aspects of Medicine. 34: 252-69. PMID 23506869 DOI: 10.1016/J.Mam.2012.07.004 |
0.372 |
|
| 2013 |
Pan Y, Chothe PP, Swaan PW. Identification of novel breast cancer resistance protein (BCRP) inhibitors by virtual screening. Molecular Pharmaceutics. 10: 1236-48. PMID 23418667 DOI: 10.1021/Mp300547H |
0.379 |
|
| 2013 |
Lynch C, Pan Y, Li L, Ferguson SS, Xia M, Swaan PW, Wang H. Identification of novel activators of constitutive androstane receptor from FDA-approved drugs by integrated computational and biological approaches. Pharmaceutical Research. 30: 489-501. PMID 23090669 DOI: 10.1007/S11095-012-0895-1 |
0.332 |
|
| 2012 |
Ekins S, Polli JE, Swaan PW, Wright SH. Computational modeling to accelerate the identification of substrates and inhibitors for transporters that affect drug disposition Clinical Pharmacology and Therapeutics. 92: 661-665. PMID 23010651 DOI: 10.1038/Clpt.2012.164 |
0.415 |
|
| 2012 |
González PM, Hussainzada N, Swaan PW, Mackerell AD, Polli JE. Putative irreversible inhibitors of the human sodium-dependent bile acid transporter (hASBT; SLC10A2) support the role of transmembrane domain 7 in substrate binding/translocation. Pharmaceutical Research. 29: 1821-31. PMID 22354836 DOI: 10.1007/S11095-012-0706-8 |
0.411 |
|
| 2011 |
Ho HT, Pan Y, Cui Z, Duan H, Swaan PW, Wang J. Molecular analysis and structure-activity relationship modeling of the substrate/inhibitor interaction site of plasma membrane monoamine transporter. The Journal of Pharmacology and Experimental Therapeutics. 339: 376-85. PMID 21816955 DOI: 10.1124/Jpet.111.184036 |
0.354 |
|
| 2011 |
da Silva TC, Hussainzada N, Khantwal CM, Polli JE, Swaan PW. Transmembrane helix 1 contributes to substrate translocation and protein stability of bile acid transporter SLC10A2. The Journal of Biological Chemistry. 286: 27322-32. PMID 21646357 DOI: 10.1074/Jbc.M110.217802 |
0.402 |
|
| 2011 |
Mason CW, Buhimschi IA, Buhimschi CS, Dong Y, Weiner CP, Swaan PW. ATP-binding cassette transporter expression in human placenta as a function of pregnancy condition. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 1000-7. PMID 21430233 DOI: 10.1124/Dmd.111.038166 |
0.335 |
|
| 2011 |
Goldberg DS, Vijayalakshmi N, Swaan PW, Ghandehari H. G3.5 PAMAM dendrimers enhance transepithelial transport of SN38 while minimizing gastrointestinal toxicity. Journal of Controlled Release : Official Journal of the Controlled Release Society. 150: 318-25. PMID 21115079 DOI: 10.1016/J.Jconrel.2010.11.022 |
0.379 |
|
| 2011 |
Pan Y, Li L, Kim G, Ekins S, Wang H, Swaan PW. Identification and validation of novel human pregnane X receptor activators among prescribed drugs via ligand-based virtual screening. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 337-44. PMID 21068194 DOI: 10.1124/Dmd.110.035808 |
0.353 |
|
| 2011 |
Pan Y, Li L, Kim G, Ekins S, Wang H, Swaan P. Identification of hPXR Modulators via SAR-Based Virtual Screening Biophysical Journal. 100: 320a. DOI: 10.1016/J.Bpj.2010.12.1948 |
0.362 |
|
| 2010 |
Zheng X, Pan Y, Acharya C, Swaan PW, Polli JE. Structural requirements of the ASBT by 3D-QSAR analysis using aminopyridine conjugates of chenodeoxycholic acid. Bioconjugate Chemistry. 21: 2038-48. PMID 20968316 DOI: 10.1021/Bc100273W |
0.404 |
|
| 2010 |
Bahadduri PM, Polli JE, Swaan PW, Ekins S. Targeting drug transporters - combining in silico and in vitro approaches to predict in vivo. Methods in Molecular Biology (Clifton, N.J.). 637: 65-103. PMID 20419430 DOI: 10.1007/978-1-60761-700-6_4 |
0.422 |
|
| 2010 |
Goldberg DS, Ghandehari H, Swaan PW. Cellular entry of G3.5 poly (amido amine) dendrimers by clathrin- and dynamin-dependent endocytosis promotes tight junctional opening in intestinal epithelia. Pharmaceutical Research. 27: 1547-57. PMID 20411406 DOI: 10.1007/S11095-010-0153-3 |
0.402 |
|
| 2010 |
Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL, Chu X, Dahlin A, Evers R, Fischer V, Hillgren KM, Hoffmaster KA, Ishikawa T, Keppler D, Kim RB, ... ... Swaan PW, et al. Membrane transporters in drug development. Nature Reviews. Drug Discovery. 9: 215-36. PMID 20190787 DOI: 10.1038/Nrd3028 |
0.393 |
|
| 2010 |
Fisher SJ, Swaan PW, Eddington ND. The ethanol metabolite acetaldehyde increases paracellular drug permeability in vitro and oral bioavailability in vivo. The Journal of Pharmacology and Experimental Therapeutics. 332: 326-33. PMID 19820208 DOI: 10.1124/Jpet.109.158642 |
0.331 |
|
| 2010 |
Goldberg DS, Swaan PW, Ghandehari H. Mechanisms of poly(amido amine) dendrimer transepithelial transport and tight junction modulation in caco-2 cells Ifmbe Proceedings. 32: 236-239. DOI: 10.1007/978-3-642-14998-6_60 |
0.335 |
|
| 2010 |
Swaan PW. Drug Transport and Membrane Transport Proteins Burger's Medicinal Chemistry and Drug Discovery. 447-498. DOI: 10.1002/0471266949.Bmc027.Pub2 |
0.44 |
|
| 2009 |
Hussainzada N, Claro Da Silva T, Swaan PW. The cytosolic half of helix III forms the substrate exit route during permeation events of the sodium/bile acid cotransporter ASBT. Biochemistry. 48: 8528-39. PMID 19653651 DOI: 10.1021/Bi900616W |
0.404 |
|
| 2009 |
Sweet DM, Kolhatkar RB, Ray A, Swaan P, Ghandehari H. Transepithelial transport of PEGylated anionic poly(amidoamine) dendrimers: implications for oral drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 138: 78-85. PMID 19393702 DOI: 10.1016/J.Jconrel.2009.04.022 |
0.408 |
|
| 2008 |
Bareford LM, Phelps MA, Foraker AB, Swaan PW. Intracellular processing of riboflavin in human breast cancer cells. Molecular Pharmaceutics. 5: 839-48. PMID 18754669 DOI: 10.1021/Mp800046M |
0.347 |
|
| 2008 |
Hussainzada N, Da Silva TC, Zhang EY, Swaan PW. Conserved aspartic acid residues lining the extracellular loop 1 of sodium-coupled bile acid transporter ASBT Interact with Na+ and 7alpha-OH moieties on the ligand cholestane skeleton. The Journal of Biological Chemistry. 283: 20653-63. PMID 18508772 DOI: 10.1074/Jbc.M802885200 |
0.373 |
|
| 2008 |
Swaan PW, Bensman T, Bahadduri PM, Hall MW, Sarkar A, Bao S, Khantwal CM, Ekins S, Knoell DL. Bacterial peptide recognition and immune activation facilitated by human peptide transporter PEPT2. American Journal of Respiratory Cell and Molecular Biology. 39: 536-42. PMID 18474668 DOI: 10.1165/Rcmb.2008-0059Oc |
0.362 |
|
| 2008 |
Bahadduri PM, Ray A, Khandelwal A, Swaan PW. Design of high-affinity peptide conjugates with optimized fluorescence quantum yield as markers for small peptide transporter PEPT1 (SLC15A1). Bioorganic & Medicinal Chemistry Letters. 18: 2555-7. PMID 18374571 DOI: 10.1016/J.Bmcl.2008.03.044 |
0.301 |
|
| 2008 |
Khantwal CM, Swaan PW. Cytosolic half of transmembrane domain IV of the human bile acid transporter hASBT (SLC10A2) forms part of the substrate translocation pathway. Biochemistry. 47: 3606-14. PMID 18311924 DOI: 10.1021/Bi702498W |
0.385 |
|
| 2008 |
Zhou H, Wu S, Zhai S, Liu A, Sun Y, Li R, Zhang Y, Ekins S, Swaan PW, Fang B, Zhang B, Yan B. Design, synthesis, cytoselective toxicity, structure-activity relationships, and pharmacophore of thiazolidinone derivatives targeting drug-resistant lung cancer cells. Journal of Medicinal Chemistry. 51: 1242-51. PMID 18257542 DOI: 10.1021/Jm7012024 |
0.626 |
|
| 2008 |
Truong DM, Kaler G, Khandelwal A, Swaan PW, Nigam SK. Multi-level analysis of organic anion transporters 1, 3, and 6 reveals major differences in structural determinants of antiviral discrimination. The Journal of Biological Chemistry. 283: 8654-63. PMID 18174163 DOI: 10.1074/Jbc.M708615200 |
0.376 |
|
| 2008 |
Kitchens KM, Kolhatkar RB, Swaan PW, Ghandehari H. Endocytosis inhibitors prevent poly(amidoamine) dendrimer internalization and permeability across Caco-2 cells. Molecular Pharmaceutics. 5: 364-9. PMID 18173246 DOI: 10.1021/Mp700089S |
0.41 |
|
| 2008 |
Fisher SJ, Lee IJ, Swaan PW, Eddington ND. Evaluation of the effect of ethanol's toxic metabolite acetaldehyde on the gastrointestinal oligopeptide transporter, PEPT1: in vitro and in vivo studies. Alcoholism, Clinical and Experimental Research. 32: 162-70. PMID 18028524 DOI: 10.1111/J.1530-0277.2007.00551.X |
0.348 |
|
| 2008 |
Banerjee A, Hussainzada N, Khandelwal A, Swaan PW. Electrostatic and potential cation-pi forces may guide the interaction of extracellular loop III with Na+ and bile acids for human apical Na+-dependent bile acid transporter. The Biochemical Journal. 410: 391-400. PMID 18028035 DOI: 10.1042/Bj20071300 |
0.405 |
|
| 2008 |
Hussainzada N, Khandewal A, Swaan PW. Conformational flexibility of helix VI is essential for substrate permeation of the human apical sodium-dependent bile acid transporter. Molecular Pharmacology. 73: 305-13. PMID 17971420 DOI: 10.1124/Mol.107.041640 |
0.393 |
|
| 2008 |
Ekins S, Ecker GF, Chiba P, Swaan PW. Future directions for drug transporter modelling. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 37: 1152-70. PMID 17968741 DOI: 10.1080/00498250701646341 |
0.416 |
|
| 2008 |
Mason C, Buhimschi C, Buhimschi I, Swaan P, Weiner CP. 55: Regulation of steroid sulfate transporters in human placenta during various pregnancy related disease states and their impact on estrogen synthesis pathway American Journal of Obstetrics and Gynecology. 199: S25. DOI: 10.1016/J.Ajog.2008.09.078 |
0.307 |
|
| 2007 |
Kolhatkar RB, Kitchens KM, Swaan PW, Ghandehari H. Surface acetylation of polyamidoamine (PAMAM) dendrimers decreases cytotoxicity while maintaining membrane permeability. Bioconjugate Chemistry. 18: 2054-60. PMID 17960872 DOI: 10.1021/Bc0603889 |
0.37 |
|
| 2007 |
Kitchens KM, Foraker AB, Kolhatkar RB, Swaan PW, Ghandehari H. Endocytosis and interaction of poly (amidoamine) dendrimers with Caco-2 cells. Pharmaceutical Research. 24: 2138-45. PMID 17701324 DOI: 10.1007/S11095-007-9415-0 |
0.312 |
|
| 2007 |
Bareford LM, Swaan PW. Endocytic mechanisms for targeted drug delivery. Advanced Drug Delivery Reviews. 59: 748-58. PMID 17659804 DOI: 10.1016/J.Addr.2007.06.008 |
0.382 |
|
| 2007 |
Ekins S, Chang C, Mani S, Krasowski MD, Reschly EJ, Iyer M, Kholodovych V, Ai N, Welsh WJ, Sinz M, Swaan PW, Patel R, Bachmann K. Human pregnane X receptor antagonists and agonists define molecular requirements for different binding sites. Molecular Pharmacology. 72: 592-603. PMID 17576789 DOI: 10.1124/Mol.107.038398 |
0.346 |
|
| 2007 |
Foraker AB, Ray A, Da Silva TC, Bareford LM, Hillgren KM, Schmittgen TD, Swaan PW. Dynamin 2 regulates riboflavin endocytosis in human placental trophoblasts. Molecular Pharmacology. 72: 553-62. PMID 17565002 DOI: 10.1124/Mol.107.037101 |
0.387 |
|
| 2007 |
Kaler G, Truong DM, Khandelwal A, Nagle M, Eraly SA, Swaan PW, Nigam SK. Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members. The Journal of Biological Chemistry. 282: 23841-53. PMID 17553798 DOI: 10.1074/Jbc.M703467200 |
0.392 |
|
| 2007 |
McKay DB, Chang C, González-Cestari TF, McKay SB, El-Hajj RA, Bryant DL, Zhu MX, Swaan PW, Arason KM, Pulipaka AB, Orac CM, Bergmeier SC. Analogs of methyllycaconitine as novel noncompetitive inhibitors of nicotinic receptors: pharmacological characterization, computational modeling, and pharmacophore development. Molecular Pharmacology. 71: 1288-97. PMID 17308033 DOI: 10.1124/Mol.106.033233 |
0.322 |
|
| 2007 |
Balakrishnan A, Hussainzada N, Gonzalez P, Bermejo M, Swaan PW, Polli JE. Bias in estimation of transporter kinetic parameters from overexpression systems: Interplay of transporter expression level and substrate affinity. The Journal of Pharmacology and Experimental Therapeutics. 320: 133-44. PMID 17038509 DOI: 10.1124/Jpet.106.107433 |
0.341 |
|
| 2006 |
Chang C, Ekins S, Bahadduri P, Swaan PW. Pharmacophore-based discovery of ligands for drug transporters. Advanced Drug Delivery Reviews. 58: 1431-50. PMID 17097188 DOI: 10.1016/J.Addr.2006.09.006 |
0.391 |
|
| 2006 |
Kitchens KM, Kolhatkar RB, Swaan PW, Eddington ND, Ghandehari H. Transport of poly(amidoamine) dendrimers across Caco-2 cell monolayers: Influence of size, charge and fluorescent labeling. Pharmaceutical Research. 23: 2818-26. PMID 17094034 DOI: 10.1007/S11095-006-9122-2 |
0.335 |
|
| 2006 |
Chang C, Bahadduri PM, Polli JE, Swaan PW, Ekins S. Rapid identification of P-glycoprotein substrates and inhibitors. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 1976-84. PMID 16997908 DOI: 10.1124/Dmd.106.012351 |
0.349 |
|
| 2006 |
Hussainzada N, Banerjee A, Swaan PW. Transmembrane domain VII of the human apical sodium-dependent bile acid transporter ASBT (SLC10A2) lines the substrate translocation pathway. Molecular Pharmacology. 70: 1565-74. PMID 16899538 DOI: 10.1124/Mol.106.028647 |
0.385 |
|
| 2006 |
D'Souza VM, Foraker AB, Free RB, Ray A, Shapiro PS, Swaan PW. cAMP-Coupled riboflavin trafficking in placental trophoblasts: a dynamic and ordered process. Biochemistry. 45: 6095-104. PMID 16681382 DOI: 10.1021/Bi060138F |
0.32 |
|
| 2006 |
D'Souza VM, Bareford LM, Ray A, Swaan PW. Cytoskeletal scaffolds regulate riboflavin endocytosis and recycling in placental trophoblasts. The Journal of Nutritional Biochemistry. 17: 821-9. PMID 16563724 DOI: 10.1016/J.Jnutbio.2006.01.008 |
0.357 |
|
| 2006 |
Hu H, Endres CJ, Chang C, Umapathy NS, Lee EW, Fei YJ, Itagaki S, Swaan PW, Ganapathy V, Unadkat JD. Electrophysiological characterization and modeling of the structure activity relationship of the human concentrative nucleoside transporter 3 (hCNT3). Molecular Pharmacology. 69: 1542-53. PMID 16446384 DOI: 10.1124/Mol.105.018945 |
0.395 |
|
| 2006 |
Banerjee A, Swaan PW. Membrane topology of human ASBT (SLC10A2) determined by dual label epitope insertion scanning mutagenesis. New evidence for seven transmembrane domains. Biochemistry. 45: 943-53. PMID 16411770 DOI: 10.1021/Bi052202J |
0.322 |
|
| 2006 |
Mason CW, D'Souza VM, Bareford LM, Phelps MA, Ray A, Swaan PW. Recognition, co-internalization, and recycling of an avian riboflavin carrier protein in human placental trophoblasts. The Journal of Pharmacology and Experimental Therapeutics. 317: 465-72. PMID 16399883 DOI: 10.1124/Jpet.105.096149 |
0.359 |
|
| 2006 |
Ray A, Banerjee A, Chang C, Khantwal CM, Swaan PW. Design of novel synthetic MTS conjugates of bile acids for site-directed sulfhydryl labeling of cysteine residues in bile acid binding and transporting proteins. Bioorganic & Medicinal Chemistry Letters. 16: 1473-6. PMID 16387497 DOI: 10.1016/J.Bmcl.2005.12.050 |
0.369 |
|
| 2006 |
Chang C, Swaan PW. Computational approaches to modeling drug transporters. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 27: 411-24. PMID 16274971 DOI: 10.1016/J.Ejps.2005.09.013 |
0.409 |
|
| 2006 |
Chang C, Ray A, Swaan P. In silico strategies for modeling membrane transporter function. Drug Discovery Today. 10: 663-71. PMID 15894231 DOI: 10.1016/S1359-6446(05)03429-X |
0.421 |
|
| 2005 |
Banerjee A, Ray A, Chang C, Swaan PW. Site-directed mutagenesis and use of bile acid-MTS conjugates to probe the role of cysteines in the human apical sodium-dependent bile acid transporter (SLC10A2). Biochemistry. 44: 8908-17. PMID 15952798 DOI: 10.1021/Bi050553S |
0.321 |
|
| 2005 |
Ekins S, Johnston JS, Bahadduri P, D'Souza VM, Ray A, Chang C, Swaan PW. In vitro and pharmacophore-based discovery of novel hPEPT1 inhibitors. Pharmaceutical Research. 22: 512-7. PMID 15846457 DOI: 10.1007/S11095-005-2505-Y |
0.362 |
|
| 2005 |
Chang C, Pang KS, Swaan PW, Ekins S. Comparative pharmacophore modeling of organic anion transporting polypeptides: a meta-analysis of rat Oatp1a1 and human OATP1B1. The Journal of Pharmacology and Experimental Therapeutics. 314: 533-41. PMID 15845861 DOI: 10.1124/Jpet.104.082370 |
0.412 |
|
| 2005 |
Xiao JJ, Foraker AB, Swaan PW, Liu S, Huang Y, Dai Z, Chen J, Sadée W, Byrd J, Marcucci G, Chan KK. Efflux of depsipeptide FK228 (FR901228, NSC-630176) is mediated by P-glycoprotein and multidrug resistance-associated protein 1. The Journal of Pharmacology and Experimental Therapeutics. 313: 268-76. PMID 15634944 DOI: 10.1124/Jpet.104.072033 |
0.391 |
|
| 2005 |
Suhre WM, Ekins S, Chang C, Swaan PW, Wright SH. Molecular determinants of substrate/inhibitor binding to the human and rabbit renal organic cation transporters hOCT2 and rbOCT2. Molecular Pharmacology. 67: 1067-77. PMID 15630081 DOI: 10.1124/Mol.104.004713 |
0.406 |
|
| 2005 |
Bahadduri PM, D'Souza VM, Pinsonneault JK, Sadée W, Bao S, Knoell DL, Swaan PW. Functional characterization of the peptide transporter PEPT2 in primary cultures of human upper airway epithelium. American Journal of Respiratory Cell and Molecular Biology. 32: 319-25. PMID 15626774 DOI: 10.1165/Rcmb.2004-0322Oc |
0.374 |
|
| 2005 |
Mason C, Swaan PW, Weiner CP. Increased small GTPases- the fundamental molecular mechanism underlying decreased myometrial responsiveness during quiescence American Journal of Obstetrics and Gynecology. 193: S10. DOI: 10.1016/J.Ajog.2005.10.023 |
0.316 |
|
| 2004 |
Phelps MA, Foraker AB, Gao W, Dalton JT, Swaan PW. A novel rhodamine-riboflavin conjugate probe exhibits distinct fluorescence resonance energy transfer that enables riboflavin trafficking and subcellular localization studies. Molecular Pharmaceutics. 1: 257-66. PMID 15981585 DOI: 10.1021/Mp0499510 |
0.313 |
|
| 2004 |
Zhang EY, Phelps MA, Banerjee A, Khantwal CM, Chang C, Helsper F, Swaan PW. Topology scanning and putative three-dimensional structure of the extracellular binding domains of the apical sodium-dependent bile acid transporter (SLC10A2). Biochemistry. 43: 11380-92. PMID 15350125 DOI: 10.1021/Bi049270A |
0.339 |
|
| 2004 |
Bohl CE, Chang C, Mohler ML, Chen J, Miller DD, Swaan PW, Dalton JT. A ligand-based approach to identify quantitative structure-activity relationships for the androgen receptor. Journal of Medicinal Chemistry. 47: 3765-76. PMID 15239655 DOI: 10.1021/Jm0499007 |
0.308 |
|
| 2004 |
Chang C, Swaan PW, Ngo LY, Lum PY, Patil SD, Unadkat JD. Molecular requirements of the human nucleoside transporters hCNT1, hCNT2, and hENT1. Molecular Pharmacology. 65: 558-70. PMID 14978234 DOI: 10.1124/Mol.65.3.558 |
0.423 |
|
| 2003 |
Yates CR, Chang C, Kearbey JD, Yasuda K, Schuetz EG, Miller DD, Dalton JT, Swaan PW. Structural determinants of P-glycoprotein-mediated transport of glucocorticoids. Pharmaceutical Research. 20: 1794-803. PMID 14661924 DOI: 10.1023/B:Pham.0000003377.39548.F6 |
0.334 |
|
| 2003 |
Foraker AB, Khantwal CM, Swaan PW. Current perspectives on the cellular uptake and trafficking of riboflavin. Advanced Drug Delivery Reviews. 55: 1467-83. PMID 14597141 DOI: 10.1016/J.Addr.2003.07.005 |
0.422 |
|
| 2003 |
Phelps MA, Foraker AB, Swaan PW. Cytoskeletal motors and cargo in membrane trafficking: opportunities for high specificity in drug intervention. Drug Discovery Today. 8: 494-502. PMID 12818519 DOI: 10.1016/S1359-6446(03)02707-7 |
0.358 |
|
| 2003 |
Huang SN, Phelps MA, Swaan PW. Involvement of endocytic organelles in the subcellular trafficking and localization of riboflavin. The Journal of Pharmacology and Experimental Therapeutics. 306: 681-7. PMID 12721324 DOI: 10.1124/Jpet.103.051581 |
0.629 |
|
| 2003 |
Swaan PW. Membrane Transport Proteins and Drug Transport Burger's Medicinal Chemistry and Drug Discovery. 249-293. DOI: 10.1002/0471266949.Bmc027 |
0.439 |
|
| 2002 |
Ekins S, Boulanger B, Swaan PW, Hupcey MA. Towards a new age of virtual ADME/TOX and multidimensional drug discovery. Journal of Computer-Aided Molecular Design. 16: 381-401. PMID 12489686 DOI: 10.1023/A:1020816005910 |
0.369 |
|
| 2002 |
Zhang EY, Knipp GT, Ekins S, Swaan PW. Structural biology and function of solute transporters: implications for identifying and designing substrates. Drug Metabolism Reviews. 34: 709-50. PMID 12487148 DOI: 10.1081/Dmr-120015692 |
0.417 |
|
| 2002 |
Ulukan H, Swaan PW. Camptothecins: a review of their chemotherapeutic potential. Drugs. 62: 2039-57. PMID 12269849 DOI: 10.2165/00003495-200262140-00004 |
0.706 |
|
| 2002 |
Zhang EY, Phelps MA, Cheng C, Ekins S, Swaan PW. Modeling of active transport systems. Advanced Drug Delivery Reviews. 54: 329-54. PMID 11922951 DOI: 10.1016/S0169-409X(02)00007-8 |
0.429 |
|
| 2001 |
Ulukan H, Muller MT, Swaan PW. Downregulation of topoisomerase I in differentiating human intestinal epithelial cells. International Journal of Cancer. 94: 200-7. PMID 11668498 DOI: 10.1002/Ijc.1463 |
0.709 |
|
| 2001 |
Huang SN, Swaan PW. Riboflavin uptake in human trophoblast-derived BeWo cell monolayers: cellular translocation and regulatory mechanisms. The Journal of Pharmacology and Experimental Therapeutics. 298: 264-71. PMID 11408551 |
0.621 |
|
| 2001 |
Ekins S, Waller CL, Swaan PW, Cruciani G, Wrighton SA, Wikel JH. Progress in predicting human ADME parameters in silico. Journal of Pharmacological and Toxicological Methods. 44: 251-72. PMID 11274894 DOI: 10.1016/S1056-8719(00)00109-X |
0.359 |
|
| 2000 |
Huang SN, Swaan PW. Involvement of a receptor-mediated component in cellular translocation of riboflavin. The Journal of Pharmacology and Experimental Therapeutics. 294: 117-25. PMID 10871302 |
0.625 |
|
| 1998 |
Swaan PW. Recent advances in intestinal macromolecular drug delivery via receptor-mediated transport pathways. Pharmaceutical Research. 15: 826-34. PMID 9647346 DOI: 10.1023/A:1011908128045 |
0.385 |
|
| 1997 |
Kågedahl M, Swaan PW, Redemann CT, Tang M, Craik CS, Szoka FC, Øie S. Use of the intestinal bile acid transporter for the uptake of cholic acid conjugates with HIV-1-protease inhibitory activity Pharmaceutical Research. 14: 176-180. PMID 9090705 DOI: 10.1023/A:1012044526054 |
0.369 |
|
| 1996 |
Swaan PW, Szoka FC, Øie S. Use of the intestinal and hepatic bile acid transporters for drug delivery Advanced Drug Delivery Reviews. 20: 59-82. DOI: 10.1016/0169-409X(95)00130-Y |
0.301 |
|
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