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Alan Kimmel - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Cell Biology
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36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Jaiswal P, Majithia AR, Rosel D, Liao XH, Khurana T, Kimmel AR. Integrated actions of mTOR complexes 1 and 2 for growth and development of Dictyostelium. The International Journal of Developmental Biology. 63: 521-527. PMID 31840789 DOI: 10.1387/ijdb.190245ak  0.429
2019 Meena NP, Jaiswal P, Chang FS, Brzostowski J, Kimmel AR. DPF is a cell-density sensing factor, with cell-autonomous and non-autonomous functions during Dictyostelium growth and development. Bmc Biology. 17: 97. PMID 31791330 DOI: 10.1186/s12915-019-0714-9  0.342
2019 Jaiswal P, Kimmel AR. mTORC1/AMPK responses define a core gene set for developmental cell fate switching. Bmc Biology. 17: 58. PMID 31319820 DOI: 10.1186/s12915-019-0673-1  0.346
2019 Kimmel AR. An ERK Phosphoproteome Expands Chemotactic Signaling in Dictyostelium. Developmental Cell. 48: 421-422. PMID 30782408 DOI: 10.1016/j.devcel.2019.02.006  0.428
2017 Meena NP, Kimmel AR. Chemotactic network responses to live bacteria show independence of phagocytosis from chemo-receptor sensing. Elife. 6. PMID 28541182 DOI: 10.7554/eLife.24627  0.314
2016 Meena NP, Kimmel AR. Biochemical Responses to Chemically Distinct Chemoattractants During the Growth and Development of Dictyostelium. Methods in Molecular Biology (Clifton, N.J.). 1407: 141-51. PMID 27271900 DOI: 10.1007/978-1-4939-3480-5_11  0.393
2014 Ludtmann MH, Otto GP, Schilde C, Chen ZH, Allan CY, Brace S, Beesley PW, Kimmel AR, Fisher P, Killick R, Williams RS. An ancestral non-proteolytic role for presenilin proteins in multicellular development of the social amoeba Dictyostelium discoideum. Journal of Cell Science. 127: 1576-84. PMID 24463814 DOI: 10.1242/Jcs.140939  0.431
2013 Platt JL, Rogers BJ, Rogers KC, Harwood AJ, Kimmel AR. Different CHD chromatin remodelers are required for expression of distinct gene sets and specific stages during development of Dictyostelium discoideum. Development (Cambridge, England). 140: 4926-36. PMID 24301467 DOI: 10.1242/dev.099879  0.325
2013 Brzostowski JA, Sawai S, Rozov O, Liao XH, Imoto D, Parent CA, Kimmel AR. Phosphorylation of chemoattractant receptors regulates chemotaxis, actin reorganization and signal relay. Journal of Cell Science. 126: 4614-26. PMID 23902692 DOI: 10.1242/jcs.122952  0.553
2013 Liao XH, Buggey J, Lee YK, Kimmel AR. Chemoattractant stimulation of TORC2 is regulated by receptor/G protein-targeted inhibitory mechanisms that function upstream and independently of an essential GEF/Ras activation pathway in Dictyostelium. Molecular Biology of the Cell. 24: 2146-55. PMID 23657816 DOI: 10.1091/mbc.E13-03-0130  0.433
2012 Rosel D, Khurana T, Majithia A, Huang X, Bhandari R, Kimmel AR. TOR complex 2 (TORC2) in Dictyostelium suppresses phagocytic nutrient capture independently of TORC1-mediated nutrient sensing. Journal of Cell Science. 125: 37-48. PMID 22266904 DOI: 10.1242/jcs.077040  0.314
2011 Kim L, Brzostowski J, Majithia A, Lee NS, McMains V, Kimmel AR. Combinatorial cell-specific regulation of GSK3 directs cell differentiation and polarity in Dictyostelium. Development (Cambridge, England). 138: 421-30. PMID 21205787 DOI: 10.1242/Dev.055335  0.685
2010 McMains VC, Myre M, Kreppel L, Kimmel AR. Dictyostelium possesses highly diverged presenilin/γ-secretase that regulates growth and cell-fate specification and can accurately process human APP: A system for functional studies of the presenilin/γ-secretase complex Dmm Disease Models and Mechanisms. 3: 581-594. PMID 20699477 DOI: 10.1242/dmm.004457  0.702
2010 Liao XH, Buggey J, Kimmel AR. Chemotactic activation of Dictyostelium AGC-family kinases AKT and PKBR1 requires separate but coordinated functions of PDK1 and TORC2. Journal of Cell Science. 123: 983-92. PMID 20200230 DOI: 10.1242/jcs.064022  0.408
2009 Liao XH, Kimmel AR. Biochemical responses to chemoattractants in Dictyostelium: ligand-receptor interactions and downstream kinase activation. Methods in Molecular Biology (Clifton, N.J.). 571: 271-81. PMID 19763973 DOI: 10.1007/978-1-60761-198-1_18  0.358
2009 Borg J, Klint C, Wierup N, Ström K, Larsson S, Sundler F, Lupi R, Marchetti P, Xu G, Kimmel A, Londos C, Holm C. Perilipin is present in islets of Langerhans and protects against lipotoxicity when overexpressed in the beta-cell line INS-1. Endocrinology. 150: 3049-57. PMID 19299455 DOI: 10.1210/En.2008-0913  0.378
2008 McMains VC, Liao XH, Kimmel AR. Oscillatory signaling and network responses during the development of Dictyostelium discoideum. Ageing Research Reviews. 7: 234-48. PMID 18657484 DOI: 10.1016/J.Arr.2008.04.003  0.73
2008 Liao XH, Majithia A, Huang X, Kimmel AR. Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism. Amino Acids. 35: 761-70. PMID 18651095 DOI: 10.1007/s00726-008-0100-3  0.479
2006 Kim L, Kimmel AR. GSK3 at the edge: regulation of developmental specification and cell polarization. Current Drug Targets. 7: 1411-9. PMID 17100581 DOI: 10.2174/1389450110607011411  0.794
2006 Brzostowski JA, Kimmel AR. Nonadaptive regulation of ERK2 in Dictyostelium: implications for mechanisms of cAMP relay. Molecular Biology of the Cell. 17: 4220-7. PMID 16870702 DOI: 10.1091/mbc.E06-05-0376  0.497
2006 Rosel D, Kimmel AR. The COP9 signalosome regulates cell proliferation of Dictyostelium discoideum. European Journal of Cell Biology. 85: 1023-34. PMID 16781008 DOI: 10.1016/j.ejcb.2006.04.006  0.387
2005 Liu X, Rubin JS, Kimmel AR. Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins. Current Biology : Cb. 15: 1989-97. PMID 16303557 DOI: 10.1016/j.cub.2005.10.050  0.355
2005 Khurana T, Brzostowski JA, Kimmel AR. A Rab21/LIM-only/CH-LIM complex regulates phagocytosis via both activating and inhibitory mechanisms. The Embo Journal. 24: 2254-64. PMID 15962002 DOI: 10.1038/sj.emboj.7600716  0.42
2004 Kimmel AR, Firtel RA. Breaking symmetries: regulation of Dictyostelium development through chemoattractant and morphogen signal-response. Current Opinion in Genetics & Development. 14: 540-9. PMID 15380246 DOI: 10.1016/j.gde.2004.08.001  0.472
2004 Kimmel AR, Parent CA, Gough NR. Teaching resources. Spatial and temporal dynamics of signaling components involved in the control of chemotaxis in Dictyostelium discoideum. Science's Stke : Signal Transduction Knowledge Environment. 2004: tr3. PMID 15161990 DOI: 10.1126/stke.2342004tr3  0.371
2004 Brzostowski JA, Parent CA, Kimmel AR. A G alpha-dependent pathway that antagonizes multiple chemoattractant responses that regulate directional cell movement. Genes & Development. 18: 805-15. PMID 15059962 DOI: 10.1101/gad.1173404  0.579
2003 Sztalryd C, Xu G, Dorward H, Tansey JT, Contreras JA, Kimmel AR, Londos C. Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation. The Journal of Cell Biology. 161: 1093-103. PMID 12810697 DOI: 10.1083/jcb.200210169  0.361
2003 Kimmel AR, Parent CA. The signal to move: D. discoideum go orienteering. Science (New York, N.Y.). 300: 1525-7. PMID 12791977 DOI: 10.1126/science.1085439  0.476
2003 Tansey JT, Huml AM, Vogt R, Davis KE, Jones JM, Fraser KA, Brasaemle DL, Kimmel AR, Londos C. Functional studies on native and mutated forms of perilipins. A role in protein kinase A-mediated lipolysis of triacylglycerols. The Journal of Biological Chemistry. 278: 8401-6. PMID 12477720 DOI: 10.1074/Jbc.M211005200  0.398
2002 Kim L, Harwood A, Kimmel AR. Receptor-dependent and tyrosine phosphatase-mediated inhibition of GSK3 regulates cell fate choice Developmental Cell. 3: 523-532. PMID 12408804 DOI: 10.1016/S1534-5807(02)00269-1  0.809
2002 Brzostowski JA, Johnson C, Kimmel AR. Galpha-mediated inhibition of developmental signal response. Current Biology : Cb. 12: 1199-208. PMID 12176329  0.459
2001 Mu X, Spanos SA, Shiloach J, Kimmel A. CRTF is a novel transcription factor that regulates multiple stages of Dictyostelium development. Development (Cambridge, England). 128: 2569-79. PMID 11493573  0.743
2000 Kim L, Kimmel AR. GSK3, a master switch regulating cell-fate specification and tumorigenesis. Current Opinion in Genetics & Development. 10: 508-14. PMID 10980428  0.796
1999 Kim L, Liu J, Kimmel AR. The novel tyrosine kinase ZAK1 activates GSK3 to direct cell fate specification. Cell. 99: 399-408. PMID 10571182  0.812
1998 Mu X, Lee B, Louis JM, Kimmel AR. Sequence-specific protein interaction with a transcriptional enhancer involved in the autoregulated expression of cAMP receptor 1 in Dictyostelium. Development (Cambridge, England). 125: 3689-98. PMID 9716534  0.719
1988 Lilly P, Klein P, Theibert A, Vaughan R, Pupillo M, Saxe K, Kimmel A, Devreotes PN. Receptor G-Protein Interactions in the Development ofDictyostelium Botanica Acta. 101: 123-127. DOI: 10.1111/J.1438-8677.1988.Tb00022.X  0.497
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