Brian R. Wamhoff - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Molecular Biology, Physiology Biology, Cell Biology

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hoang SA, Oseini A, Feaver RE, Cole BK, Asgharpour A, Vincent R, Siddiqui M, Lawson MJ, Day NC, Taylor JM, Wamhoff BR, Mirshahi F, Contos MJ, Idowu M, Sanyal AJ. Gene Expression Predicts Histological Severity and Reveals Distinct Molecular Profiles of Nonalcoholic Fatty Liver Disease. Scientific Reports. 9: 12541. PMID 31467298 DOI: 10.1038/S41598-019-48746-5  0.304
2017 Collado MS, Cole BK, Figler RA, Lawson M, Manka D, Simmers MB, Hoang S, Serrano F, Blackman BR, Sinha S, Wamhoff BR. Exposure of Induced Pluripotent Stem Cell-Derived Vascular Endothelial and Smooth Muscle Cells in Coculture to Hemodynamics Induces Primary Vascular Cell-Like Phenotypes. Stem Cells Translational Medicine. PMID 28628273 DOI: 10.1002/Sctm.17-0004  0.477
2016 Feaver RE, Cole BK, Lawson MJ, Hoang SA, Marukian S, Blackman BR, Figler RA, Sanyal AJ, Wamhoff BR, Dash A. Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis. Jci Insight. 1: e90954. PMID 27942596 DOI: 10.1172/Jci.Insight.90954  0.341
2016 Dash A, Figler RA, Blackman BR, Marukian S, Collado MS, Lawson MJ, Hoang SA, Mackey AJ, Manka D, Cole BK, Feaver RE, Sanyal AJ, Wamhoff BR. Pharmacotoxicology of clinically-relevant concentrations of obeticholic acid in an organotypic human hepatocyte system. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 27939613 DOI: 10.1016/J.Tiv.2016.11.014  0.313
2016 Simmers MB, Cole BK, Ogletree ML, Chen Z, Xu Y, Kong LJ, Mackman N, Blackman BR, Wamhoff BR. Hemodynamics associated with atrial fibrillation directly alters thrombotic potential of endothelial cells. Thrombosis Research. 143: 34-39. PMID 27179130 DOI: 10.1016/J.Thromres.2016.04.022  0.398
2015 Terelius Y, Figler RA, Marukian S, Collado MS, Lawson MJ, Mackey AJ, Manka D, Qualls CW, Blackman BR, Wamhoff BR, Dash A. Transcriptional Profiling Suggests That Nevirapine and Ritonavir Cause Drug Induced Liver Injury Through Distinct Mechanisms in Primary Human Hepatocytes. Chemico-Biological Interactions. PMID 26626330 DOI: 10.1016/J.Cbi.2015.11.023  0.328
2015 Cole BK, Simmers MB, Feaver R, Qualls CW, Collado MS, Berzin E, Figler RA, Pryor AW, Lawson M, Mackey A, Manka D, Wamhoff BR, Turk JR, Blackman BR. An In Vitro Cynomolgus Vascular Surrogate System for Preclinical Drug Assessment and Human Translation. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 2185-95. PMID 26293464 DOI: 10.1161/Atvbaha.115.306245  0.3
2012 Halterman JA, Kwon HM, Leitinger N, Wamhoff BR. NFAT5 expression in bone marrow-derived cells enhances atherosclerosis and drives macrophage migration. Frontiers in Physiology. 3: 313. PMID 22934063 DOI: 10.3389/Fphys.2012.00313  0.738
2012 Phillips LC, Klibanov AL, Wamhoff BR, Hossack JA. Intravascular ultrasound detection and delivery of molecularly targeted microbubbles for gene delivery. Ieee Transactions On Ultrasonics, Ferroelectrics, and Frequency Control. 59: 1596-601. PMID 22828854 DOI: 10.1109/Tuffc.2012.2359  0.346
2012 Halterman JA, Kwon HM, Wamhoff BR. Tonicity-independent regulation of the osmosensitive transcription factor TonEBP (NFAT5). American Journal of Physiology. Cell Physiology. 302: C1-8. PMID 21998140 DOI: 10.1152/Ajpcell.00327.2011  0.733
2011 Lee MY, Garvey SM, Ripley ML, Wamhoff BR. Genome-wide microarray analyses identify the protein C receptor as a novel calcineurin/nuclear factor of activated T cells-dependent gene in vascular smooth muscle cell phenotypic modulation. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2665-75. PMID 21903947 DOI: 10.1161/Atvbaha.111.235960  0.735
2011 Halterman JA, Kwon HM, Zargham R, Bortz PD, Wamhoff BR. Nuclear factor of activated T cells 5 regulates vascular smooth muscle cell phenotypic modulation. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2287-96. PMID 21757659 DOI: 10.1161/Atvbaha.111.232165  0.747
2011 Phillips LC, Klibanov AL, Wamhoff BR, Hossack JA. Localized ultrasound enhances delivery of rapamycin from microbubbles to prevent smooth muscle proliferation. Journal of Controlled Release : Official Journal of the Controlled Release Society. 154: 42-9. PMID 21549778 DOI: 10.1016/J.Jconrel.2011.04.020  0.404
2011 Gelfand BD, Meller J, Pryor AW, Kahn M, Bortz PD, Wamhoff BR, Blackman BR. Hemodynamic activation of beta-catenin and T-cell-specific transcription factor signaling in vascular endothelium regulates fibronectin expression. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1625-33. PMID 21527747 DOI: 10.1161/Atvbaha.111.227827  0.477
2011 Sefcik LS, Aronin CE, Awojoodu AO, Shin SJ, Mac Gabhann F, MacDonald TL, Wamhoff BR, Lynch KR, Peirce SM, Botchwey EA. Selective activation of sphingosine 1-phosphate receptors 1 and 3 promotes local microvascular network growth. Tissue Engineering. Part A. 17: 617-29. PMID 20874260 DOI: 10.1089/Ten.Tea.2010.0404  0.328
2010 Phillips LC, Klibanov AL, Wamhoff BR, Hossack JA. Targeted gene transfection from microbubbles into vascular smooth muscle cells using focused, ultrasound-mediated delivery. Ultrasound in Medicine & Biology. 36: 1470-80. PMID 20800174 DOI: 10.1016/J.Ultrasmedbio.2010.06.010  0.414
2010 Kadl A, Meher AK, Sharma PR, Lee MY, Doran AC, Johnstone SR, Elliott MR, Gruber F, Han J, Chen W, Kensler T, Ravichandran KS, Isakson BE, Wamhoff BR, Leitinger N. Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2. Circulation Research. 107: 737-46. PMID 20651288 DOI: 10.1161/Circresaha.109.215715  0.607
2010 Mathews TP, Kennedy AJ, Kharel Y, Kennedy PC, Nicoara O, Sunkara M, Morris AJ, Wamhoff BR, Lynch KR, Macdonald TL. Discovery, biological evaluation, and structure-activity relationship of amidine based sphingosine kinase inhibitors. Journal of Medicinal Chemistry. 53: 2766-78. PMID 20205392 DOI: 10.1021/Jm901860H  0.308
2010 Garvey SM, Sinden DS, Schoppee Bortz PD, Wamhoff BR. Cyclosporine up-regulates Krüppel-like factor-4 (KLF4) in vascular smooth muscle cells and drives phenotypic modulation in vivo. The Journal of Pharmacology and Experimental Therapeutics. 333: 34-42. PMID 20089806 DOI: 10.1124/Jpet.109.163949  0.497
2010 Petrie Aronin CE, Sefcik LS, Tholpady SS, Tholpady A, Sadik KW, Macdonald TL, Peirce SM, Wamhoff BR, Lynch KR, Ogle RC, Botchwey EA. FTY720 promotes local microvascular network formation and regeneration of cranial bone defects. Tissue Engineering. Part A. 16: 1801-9. PMID 20038198 DOI: 10.1089/Ten.Tea.2009.0539  0.352
2010 Nilsson-Berglund LM, Zetterqvist AV, Nilsson-Ohman J, Sigvardsson M, González Bosc LV, Smith ML, Salehi A, Agardh E, Fredrikson GN, Agardh CD, Nilsson J, Wamhoff BR, HultgÃ¥rdh-Nilsson A, Gomez MF. Nuclear factor of activated T cells regulates osteopontin expression in arterial smooth muscle in response to diabetes-induced hyperglycemia. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 218-24. PMID 19965778 DOI: 10.1161/Atvbaha.109.199299  0.467
2010 Lee MY, Garvey SM, Baras AS, Lemmon JA, Gomez MF, Schoppee Bortz PD, Daum G, LeBoeuf RC, Wamhoff BR. Integrative genomics identifies DSCR1 (RCAN1) as a novel NFAT-dependent mediator of phenotypic modulation in vascular smooth muscle cells. Human Molecular Genetics. 19: 468-79. PMID 19926569 DOI: 10.1093/hmg/ddp511  0.71
2010 Orr AW, Hastings NE, Blackman BR, Wamhoff BR. Complex regulation and function of the inflammatory smooth muscle cell phenotype in atherosclerosis. Journal of Vascular Research. 47: 168-80. PMID 19851078 DOI: 10.1159/000250095  0.498
2009 Long X, Tharp DL, Georger MA, Slivano OJ, Lee MY, Wamhoff BR, Bowles DK, Miano JM. The smooth muscle cell-restricted KCNMB1 ion channel subunit is a direct transcriptional target of serum response factor and myocardin. The Journal of Biological Chemistry. 284: 33671-82. PMID 19801679 DOI: 10.1074/Jbc.M109.050419  0.697
2009 Hastings NE, Feaver RE, Lee MY, Wamhoff BR, Blackman BR. Human IL-8 regulates smooth muscle cell VCAM-1 expression in response to endothelial cells exposed to atheroprone flow. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 725-31. PMID 19229069 DOI: 10.1161/Atvbaha.109.184382  0.64
2009 Thomas JA, Deaton RA, Hastings NE, Shang Y, Moehle CW, Eriksson U, Topouzis S, Wamhoff BR, Blackman BR, Owens GK. PDGF-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns. American Journal of Physiology. Heart and Circulatory Physiology. 296: H442-52. PMID 19028801 DOI: 10.1152/Ajpheart.00165.2008  0.523
2009 Orr AW, Lee MY, Lemmon JA, Yurdagul A, Gomez MF, Bortz PD, Wamhoff BR. Molecular mechanisms of collagen isotype-specific modulation of smooth muscle cell phenotype. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 225-31. PMID 19023090 DOI: 10.1161/Atvbaha.108.178749  0.682
2008 Lemmon JA, Wamhoff BR. "FRNKly, smooth muscle, I don't give a CArG!": a novel mechanism for smooth muscle cell differentiation. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2091-3. PMID 19020312 DOI: 10.1161/Atvbaha.108.176875  0.526
2008 Wamhoff BR, Lynch KR, Macdonald TL, Owens GK. Sphingosine-1-phosphate receptor subtypes differentially regulate smooth muscle cell phenotype. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1454-61. PMID 18535287 DOI: 10.1161/Atvbaha.107.159392  0.344
2007 Hastings NE, Simmers MB, McDonald OG, Wamhoff BR, Blackman BR. Atherosclerosis-prone hemodynamics differentially regulates endothelial and smooth muscle cell phenotypes and promotes pro-inflammatory priming. American Journal of Physiology. Cell Physiology. 293: C1824-33. PMID 17913848 DOI: 10.1152/Ajpcell.00385.2007  0.506
2007 Jin L, Kern MJ, Otey CA, Wamhoff BR, Somlyo AV. Angiotensin II, focal adhesion kinase, and PRX1 enhance smooth muscle expression of lipoma preferred partner and its newly identified binding partner palladin to promote cell migration. Circulation Research. 100: 817-25. PMID 17322171 DOI: 10.1161/01.Res.0000261351.54147.De  0.478
2007 Zargham R, Wamhoff BR, Thibault G. RNA interference targeting alpha8 integrin attenuates smooth muscle cell growth. Febs Letters. 581: 939-43. PMID 17300786 DOI: 10.1016/J.Febslet.2007.01.069  0.36
2007 Wamhoff BR, Sinha S, Owens GK. Conditional mouse models to study developmental and pathophysiological gene function in muscle. Handbook of Experimental Pharmacology. 441-68. PMID 17203666 DOI: 10.1007/978-3-540-35109-2_18  0.468
2006 Hoofnagle MH, Thomas JA, Wamhoff BR, Owens GK. Origin of neointimal smooth muscle: we've come full circle. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 2579-81. PMID 17110606 DOI: 10.1161/01.Atv.0000249623.79871.Bc  0.441
2006 Tharp DL, Wamhoff BR, Turk JR, Bowles DK. Upregulation of intermediate-conductance Ca2+-activated K+ channel (IKCa1) mediates phenotypic modulation of coronary smooth muscle. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2493-503. PMID 16798818 DOI: 10.1152/Ajpheart.01254.2005  0.448
2006 Wamhoff BR, Bowles DK, Owens GK. Excitation-transcription coupling in arterial smooth muscle. Circulation Research. 98: 868-78. PMID 16614312 DOI: 10.1161/01.RES.0000216596.73005.3c  0.37
2006 Sinha S, Wamhoff BR, Hoofnagle MH, Thomas J, Neppl RL, Deering T, Helmke BP, Bowles DK, Somlyo AV, Owens GK. Assessment of contractility of purified smooth muscle cells derived from embryonic stem cells. Stem Cells (Dayton, Ohio). 24: 1678-88. PMID 16601077 DOI: 10.1634/Stemcells.2006-0002  0.453
2006 McDonald OG, Wamhoff BR, Hoofnagle MH, Owens GK. Control of SRF binding to CArG box chromatin regulates smooth muscle gene expression in vivo. The Journal of Clinical Investigation. 116: 36-48. PMID 16395403 DOI: 10.1172/Jci26505  0.386
2006 Wamhoff BR, Lynch K, Owens GK. Differential regulation of smooth muscle cell phenotype by sphingosine-1-phosphate receptors. The Faseb Journal. 20. DOI: 10.1096/Fasebj.20.4.A699-C  0.457
2005 O'Neill TJ, Wamhoff BR, Owens GK, Skalak TC. Mobilization of bone marrow-derived cells enhances the angiogenic response to hypoxia without transdifferentiation into endothelial cells. Circulation Research. 97: 1027-35. PMID 16210550 DOI: 10.1161/01.Res.0000189259.69645.25  0.471
2005 Hendrix JA, Wamhoff BR, McDonald OG, Sinha S, Yoshida T, Owens GK. 5' CArG degeneracy in smooth muscle alpha-actin is required for injury-induced gene suppression in vivo. The Journal of Clinical Investigation. 115: 418-27. PMID 15690088 DOI: 10.1172/Jci22648  0.503
2004 Wamhoff BR, Hoofnagle MH, Burns A, Sinha S, McDonald OG, Owens GK. A G/C element mediates repression of the SM22alpha promoter within phenotypically modulated smooth muscle cells in experimental atherosclerosis. Circulation Research. 95: 981-8. PMID 15486317 DOI: 10.1161/01.Res.0000147961.09840.Fb  0.446
2004 Owens GK, Kumar MS, Wamhoff BR. Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiological Reviews. 84: 767-801. PMID 15269336 DOI: 10.1152/Physrev.00041.2003  0.525
2004 Wamhoff BR, Bowles DK, McDonald OG, Sinha S, Somlyo AP, Somlyo AV, Owens GK. L-type voltage-gated Ca2+ channels modulate expression of smooth muscle differentiation marker genes via a rho kinase/myocardin/SRF-dependent mechanism. Circulation Research. 95: 406-14. PMID 15256479 DOI: 10.1161/01.Res.0000138582.36921.9E  0.402
2004 Hoofnagle MH, Wamhoff BR, Owens GK. Lost in transdifferentiation. The Journal of Clinical Investigation. 113: 1249-51. PMID 15124012 DOI: 10.1172/Jci21761  0.451
2004 Sinha S, Hoofnagle M, Kingston P, Wamhoff B, Owens G. ROLE OF TRANSFORMING GROWTH FACTOR (TGF)- β SIGNALING IN THE DEVELOPMENT OF CONTRACTILE SMOOTH MUSCLE CELLS (SMC) FROM EMBRYONIC STEM CELLS Cardiovascular Pathology. 13: 72. DOI: 10.1016/J.Carpath.2004.03.214  0.407
2003 Yoshida T, Sinha S, Dandré F, Wamhoff BR, Hoofnagle MH, Kremer BE, Wang DZ, Olson EN, Owens GK. Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes. Circulation Research. 92: 856-64. PMID 12663482 DOI: 10.1161/01.Res.0000068405.49081.09  0.501
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