| Year |
Citation |
Score |
| 2022 |
Morgan L, Antenos M, Kirby GM. Nrf2-mediated induction of Cyp2a5 partially protects against reductive endoplasmic reticulum stress in mouse hepatocytes. Toxicology. 471: 153162. PMID 35341795 DOI: 10.1016/j.tox.2022.153162 |
0.526 |
|
| 2021 |
Kim SD, Morgan L, Hargreaves E, Zhang X, Jiang Z, Antenos M, Li B, Kirby GM. Regulation of Cytochrome P450 2a5 by and 6,7-Dimethylesculetin in Mouse Hepatocytes. Frontiers in Pharmacology. 12: 730416. PMID 34880749 DOI: 10.3389/fphar.2021.730416 |
0.515 |
|
| 2019 |
Jiang Z, Guo X, Zhang K, Sekaran G, Cao B, Zhao Q, Zhang S, Kirby GM, Zhang X. The Essential Oils and Eucalyptol From L. Prevent Acetaminophen-Induced Liver Injury by Activating Nrf2-Keap1 and Enhancing APAP Clearance Through Non-Toxic Metabolic Pathway. Frontiers in Pharmacology. 10: 782. PMID 31404264 DOI: 10.3389/fphar.2019.00782 |
0.494 |
|
| 2013 |
Kim SD, Antenos M, Squires EJ, Kirby GM. Cytochrome P450 2A5 and bilirubin: mechanisms of gene regulation and cytoprotection. Toxicology and Applied Pharmacology. 270: 129-38. PMID 23628428 DOI: 10.1016/j.taap.2013.04.013 |
0.465 |
|
| 2011 |
Kirby GM, Nichols KD, Antenos M. CYP2A5 induction and hepatocellular stress: an adaptive response to perturbations of heme homeostasis. Current Drug Metabolism. 12: 186-97. PMID 21395539 |
0.535 |
|
| 2008 |
Nichols KD, Kirby GM. Expression of cytochrome P450 2A5 in a glucose-6-phosphate dehydrogenase-deficient mouse model of oxidative stress. Biochemical Pharmacology. 75: 1230-9. PMID 18068688 DOI: 10.1016/j.bcp.2007.10.032 |
0.475 |
|
| 2008 |
Onica T, Nichols K, Larin M, Ng L, Maslen A, Dvorak Z, Pascussi JM, Vilarem MJ, Maurel P, Kirby GM. Dexamethasone-mediated up-regulation of human CYP2A6 involves the glucocorticoid receptor and increased binding of hepatic nuclear factor 4 alpha to the proximal promoter. Molecular Pharmacology. 73: 451-60. PMID 17978169 DOI: 10.1124/Mol.107.039354 |
0.442 |
|
| 2008 |
Nichols KD, Kirby GM. Microarray analysis of hepatic gene expression in pyrazole-mediated hepatotoxicity: identification of potential stimuli of Cyp2a5 induction. Biochemical Pharmacology. 75: 538-51. PMID 17945193 DOI: 10.1016/j.bcp.2007.09.009 |
0.432 |
|
| 2006 |
Romero L, Andrews K, Ng L, O'Rourke K, Maslen A, Kirby G. Human GSTA1-1 reduces c-Jun N-terminal kinase signalling and apoptosis in Caco-2 cells Biochemical Journal. 400: 135-141. PMID 16836488 DOI: 10.1042/Bj20060110 |
0.425 |
|
| 2006 |
Romero L, Ng L, Kirby GM. Chemical inducers of rodent glutathione s-transferases down-regulate human GSTA1 transcription through a mechanism involving variant hepatic nuclear factor 1-C. Molecular Pharmacology. 70: 277-86. PMID 16608922 DOI: 10.1124/mol.105.018622 |
0.359 |
|
| 2004 |
Gilmore WJ, Kirby GM. Endoplasmic reticulum stress due to altered cellular redox status positively regulates murine hepatic CYP2A5 expression. The Journal of Pharmacology and Experimental Therapeutics. 308: 600-8. PMID 14610226 DOI: 10.1124/jpet.103.060111 |
0.546 |
|
| 2003 |
Gilmore WJ, Hartmann G, Piquette-Miller M, Marriott J, Kirby GM. Effects of lipopolysaccharide-stimulated inflammation and pyrazole-mediated hepatocellular injury on mouse hepatic Cyp2a5 expression. Toxicology. 184: 211-26. PMID 12499123 |
0.543 |
|
| 2001 |
Gilmore J, Rotondo F, Pelletier AM, LaMarre J, Alaoui-Jamali M, Kirby GM. Identification of a 43-kDa protein in human liver cytosol that binds to the 3′-untranslated region of CYP2A6 mRNA Biochemical Pharmacology. 62: 669-678. PMID 11551511 DOI: 10.1016/S0006-2952(01)00720-1 |
0.407 |
|
| 1998 |
Benn SJ, Allan A, Laithwaite JE, Tsukamoto Y, Yamate J, Kirby G, LaMarre J. Effect of extracellular matrix on gene expression and mRNA stability in primary rat hepatocytes Journal of Toxicologic Pathology. 11: 219-227. DOI: 10.1293/Tox.11.219 |
0.433 |
|
| 1996 |
Kirby GM, Batist G, Alpert L, Lamoureux E, Cameron RG, Alaoui-Jamali MA. Overexpression of cytochrome P-450 isoforms involved in aflatoxin B1 bioactivation in human liver with cirrhosis and hepatitis Toxicologic Pathology. 24: 458-467. PMID 8864187 DOI: 10.1177/019262339602400408 |
0.489 |
|
| 1996 |
Kirby GM, Stalker MJ, Gordon S, Quinn BA, van Schooten FJ, Hayes MA. Influences of chronic cholangiohepatitis and cholestasis on hepatic metabolism of benzo[a]pyrene in white suckers (Catostomus commersoni) from industrially polluted areas of Lake Ontario. Carcinogenesis. 16: 2923-9. PMID 8603465 DOI: 10.1093/carcin/16.12.2923 |
0.396 |
|
| 1994 |
Kirby GM, Wolf CR, Neal GE, Judah DJ, Henderson CJ, Srivatanakul P, Wild CP. In vitro metabolism of aflatoxin B1 by normal and tumorous liver tissue from Thailand. Carcinogenesis. 14: 2613-20. PMID 8269634 DOI: 10.1093/carcin/14.12.2613 |
0.478 |
|
| 1994 |
Pelkonen P, Kirby GM, Wild CP, Bartsch H, Lang MA. Metabolism of nitrosamines and aflatoxin B1 by hamster liver CYP2A enzymes Chemico-Biological Interactions. 93: 41-50. PMID 8069948 DOI: 10.1016/0009-2797(94)90084-1 |
0.303 |
|
| 1994 |
Kirby GM, Pelkonen P, Vatanasapt V, Camus AM, Wild CP, Lang MA. Association of liver fluke (Opisthorchis viverrini) infestation with increased expression of cytochrome p450 and carcinogen metabolism in male hamster liver Molecular Carcinogenesis. 11: 81-89. PMID 7916996 DOI: 10.1002/mc.2940110205 |
0.449 |
|
| 1994 |
Kirby G, Chemin I, Montesano R, Chisari FV, Lang MA, Wild CP. Induction of specific cytochrome p450s involved in aflatoxin B1 metabolism in hepatitis B virus transgenic mice Molecular Carcinogenesis. 11: 74-80. PMID 7916995 DOI: 10.1002/Mc.2940110204 |
0.475 |
|
| 1991 |
Kirby GM, Stalker M, Metcalfe C, Kocal T, Ferguson H, Hayes MA. Expression of immunoreactive glutathione S-transferases in hepatic neoplasms induced by aflatoxin B1 or 1,2-dimethylbenzanthracene in rainbow trout (Oncorhynchus mykiss). Carcinogenesis. 11: 2255-7. PMID 1702371 DOI: 10.1093/carcin/11.12.2255 |
0.399 |
|
| 1991 |
Stalker MJ, Kirby GM, Kocal TE, Smith IR, Hayes MA. Loss of glutathione S-transferases in pollution-associated liver neoplasms in white suckers (Catostomus commersoni) from Lake Ontario. Carcinogenesis. 12: 2221-6. PMID 1660792 DOI: 10.1093/carcin/12.12.2221 |
0.353 |
|
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