| Year |
Citation |
Score |
| 2020 |
Yu J, Yu D, Lane S, McConnachie L, Ho RJ. Controlled solvent removal from antiviral drugs and excipients in solution enables the formation of novel combination multi-drug-motifs in pharmaceutical powders composed of lopinavir, ritonavir and tenofovir. Journal of Pharmaceutical Sciences. PMID 32791073 DOI: 10.1016/J.Xphs.2020.08.003 |
0.359 |
|
| 2020 |
Mu Q, Yu J, Griffin JI, Wu Y, Zhu L, McConnachie LA, Ho RJY. Novel drug combination nanoparticles exhibit enhanced plasma exposure and dose-responsive effects on eliminating breast cancer lung metastasis. Plos One. 15: e0228557. PMID 32142553 DOI: 10.1371/Journal.Pone.0228557 |
0.34 |
|
| 2020 |
Perazzolo S, Shireman LM, McConnachie LA, Koehn J, Kinman L, Lee W, Lane S, Collier AC, Shen DD, Ho RJY. Integration of computational and experimental approaches to elucidate mechanisms of first-pass lymphatic drug sequestration and long-acting pharmacokinetics of the injectable triple-HIV drug combination TLC-ART 101. Journal of Pharmaceutical Sciences. PMID 32006525 DOI: 10.1016/J.Xphs.2020.01.016 |
0.395 |
|
| 2018 |
Perazzolo S, Shireman LM, Koehn J, McConnachie LA, Kraft JC, Shen DD, Ho RJY. Three HIV drugs, atazanavir, ritonavir and tenofovir co-formulated in drug-combination nanoparticles exhibit long-acting and lymphocyte targeting properties in non-human primates. Journal of Pharmaceutical Sciences. PMID 30121315 DOI: 10.1016/J.Xphs.2018.07.032 |
0.393 |
|
| 2018 |
Koehn J, Iwamoto JF, Kraft JC, McCONNACHIE LA, Collier AC, Ho RJY. Extended cell and plasma drug levels after one dose of a 3-in-1 nanosuspension containing lopinavir, efavirenz, and tenofovir in non-human primates. Aids (London, England). PMID 30102655 DOI: 10.1097/Qad.0000000000001969 |
0.363 |
|
| 2018 |
Mcconnachie LA, Kinman LM, Koehn J, Kraft JC, Lane S, Lee W, Collier AC, Ho RJY. Long-Acting Profile of Four Drugs in One anti-HIV Nanosuspension in Non-Human Primates for Five Weeks Following a Single Subcutaneous Injection. Journal of Pharmaceutical Sciences. PMID 29548975 DOI: 10.1016/J.Xphs.2018.03.005 |
0.381 |
|
| 2018 |
Kraft JC, McConnachie LA, Koehn J, Kinman L, Sun J, Collier AC, Collins C, Shen DD, Ho RJY. Mechanism-based pharmacokinetic (MBPK) models describe the complex plasma kinetics of three antiretrovirals delivered by a long-acting anti-HIV drug combination nanoparticle formulation. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29432823 DOI: 10.1016/J.Jconrel.2018.02.003 |
0.378 |
|
| 2017 |
Mu Q, Yu J, McConnachie LA, Kraft JC, Gao Y, Gulati GK, Ho RJY. Translation of Combination Nanodrugs into Nanomedicines: Lessons Learned and Future Outlook. Journal of Drug Targeting. 1-31. PMID 29285948 DOI: 10.1080/1061186X.2017.1419363 |
0.341 |
|
| 2017 |
Kraft JC, McConnachie LA, Koehn J, Kinman L, Collins C, Shen DD, Collier AC, Ho RJ. Long-acting combination anti-HIV drug suspension enhances and sustains higher drug levels in lymph node cells than in blood cells and plasma. Aids (London, England). PMID 28099191 DOI: 10.1097/Qad.0000000000001405 |
0.358 |
|
| 2015 |
Scoville DK, White CC, Botta D, McConnachie LA, Zadworny ME, Schmuck SC, Hu X, Gao X, Yu J, Dills RL, Sheppard L, Delaney MA, Griffith WC, Beyer RP, Zangar RC, et al. Susceptibility to quantum dot induced lung inflammation differs widely among the Collaborative Cross founder mouse strains. Toxicology and Applied Pharmacology. PMID 26476918 DOI: 10.1016/J.Taap.2015.09.019 |
0.301 |
|
| 2013 |
McConnachie LA, Botta D, White CC, Weldy CS, Wilkerson HW, Yu J, Dills R, Yu X, Griffith WC, Faustman EM, Farin FM, Gill SE, Parks WC, Hu X, Gao X, et al. The Glutathione Synthesis Gene Gclm Modulates Amphiphilic Polymer-Coated CdSe/ZnS Quantum Dot-Induced Lung Inflammation in Mice Plos One. 8. PMID 23724032 DOI: 10.1371/Journal.Pone.0064165 |
0.363 |
|
| 2012 |
Nakamura BN, Mohar I, Lawson GW, Cortés MM, Hoang YD, Ortiz L, Patel R, Rau BA, McConnachie LA, Kavanagh TJ, Luderer U. Increased sensitivity to testicular toxicity of transplacental benzo[a]pyrene exposure in male glutamate cysteine ligase modifier subunit knockout (Gclm-/-) mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 126: 227-41. PMID 22253057 DOI: 10.1093/Toxsci/Kfs017 |
0.317 |
|
| 2011 |
Nakamura BN, Fielder TJ, Hoang YD, Lim J, McConnachie LA, Kavanagh TJ, Luderer U. Lack of maternal glutamate cysteine ligase modifier subunit (Gclm) decreases oocyte glutathione concentrations and disrupts preimplantation development in mice. Endocrinology. 152: 2806-15. PMID 21558310 DOI: 10.1210/En.2011-0207 |
0.306 |
|
| 2009 |
Mohar I, Botta D, White CC, McConnachie LA, Kavanagh TJ. Glutamate cysteine ligase (GCL) transgenic and gene-targeted mice for controlling glutathione synthesis. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit6.16. PMID 23045016 DOI: 10.1002/0471140856.Tx0616S39 |
0.343 |
|
| 2008 |
Botta D, White CC, Vliet-Gregg P, Mohar I, Shi S, McGrath MB, McConnachie LA, Kavanagh TJ. Modulating GSH synthesis using glutamate cysteine ligase transgenic and gene-targeted mice. Drug Metabolism Reviews. 40: 465-77. PMID 18642143 DOI: 10.1080/03602530802186587 |
0.372 |
|
| 2007 |
McConnachie LA, Mohar I, Hudson FN, Ware CB, Ladiges WC, Fernandez C, Chatterton-Kirchmeier S, White CC, Pierce RH, Kavanagh TJ. Glutamate cysteine ligase modifier subunit deficiency and gender as determinants of acetaminophen-induced hepatotoxicity in mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 99: 628-36. PMID 17584759 DOI: 10.1093/Toxsci/Kfm165 |
0.357 |
|
| 2006 |
Giordano G, White CC, McConnachie LA, Fernandez C, Kavanagh TJ, Costa LG. Neurotoxicity of domoic Acid in cerebellar granule neurons in a genetic model of glutathione deficiency. Molecular Pharmacology. 70: 2116-26. PMID 17000861 DOI: 10.1124/Mol.106.027748 |
0.307 |
|
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