| Year |
Citation |
Score |
| 2022 |
Teslenko I, Trudeau J, Luo S, Watson CJW, Chen G, Truica CI, Lazarus P. . The Journal of Pharmacology and Experimental Therapeutics. PMID 35793834 DOI: 10.1124/jpet.122.001232 |
0.301 |
|
| 2022 |
Liu H, Li G, Sturgis EM, Shete S, Dahlstrom KR, Du M, Amos CI, Christiani DC, Lazarus P, Wei Q. Genetic variants in CYP2B6 and HSD17B12 associated with risk of squamous cell carcinoma of the head and neck. International Journal of Cancer. PMID 35404482 DOI: 10.1002/ijc.34023 |
0.304 |
|
| 2022 |
Perez-Paramo YX, Watson CJW, Chen G, Lazarus P. CYP2C19 plays a major role in the hepatic -oxidation of cotinine. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 35197312 DOI: 10.1124/dmd.121.000624 |
0.301 |
|
| 2020 |
Vergara A, Watson C, Watson JM, Chen G, Lazarus P. Altered metabolism of polycyclic aromatic hydrocarbons by UDP-glycosyltransferase 3A2 (UGT3A2) missense variants. Chemical Research in Toxicology. PMID 32993298 DOI: 10.1021/acs.chemrestox.0c00233 |
0.331 |
|
| 2020 |
Sun R, Xu M, Li X, Gaynor S, Zhou H, Li Z, Bossé Y, Lam S, Tsao MS, Tardon A, Chen C, Doherty J, Goodman G, Bojesen SE, Landi MT, ... ... Lazarus P, et al. Integration of multiomic annotation data to prioritize and characterize inflammation and immune-related risk variants in squamous cell lung cancer. Genetic Epidemiology. PMID 32924180 DOI: 10.1002/Gepi.22358 |
0.363 |
|
| 2020 |
Zhou W, Liu G, Hung RJ, Haycock PC, Aldrich MC, Andrew AS, Arnold SM, Bickeböller H, Bojesen SE, Brennan P, Brunnström H, Melander O, Caporaso NE, Landi MT, Chen C, ... ... Lazarus P, et al. Causal Relationships between Body Mass Index, Smoking, and Lung Cancer: Univariable and Multivariable Mendelian Randomization. International Journal of Cancer. PMID 32914876 DOI: 10.1002/Ijc.33292 |
0.362 |
|
| 2020 |
Qin N, Li Y, Wang C, Zhu M, Dai J, Hong T, Albanes D, Lam S, Tardon A, Chen C, Goodman G, Bojesen SE, Landi MT, Johansson M, Risch A, ... ... Lazarus P, et al. Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma. Frontiers of Medicine. PMID 32889700 DOI: 10.1007/S11684-020-0779-4 |
0.329 |
|
| 2020 |
Ji X, Mukherjee S, Landi MT, Bosse Y, Joubert P, Zhu D, Gorlov I, Xiao X, Han Y, Gorlova O, Hung RJ, Brhane Y, Carreras-Torres R, Christiani DC, Caporaso N, ... ... Lazarus P, et al. Protein-altering germline mutations implicate novel genes related to lung cancer development. Nature Communications. 11: 2220. PMID 32393777 DOI: 10.1038/S41467-020-15905-6 |
0.373 |
|
| 2020 |
Wang Y, Gorlova OY, Gorlov IP, Zhu M, Dai J, Albanes D, Lam S, Tardon A, Chen C, Goodman GE, Bojesen SE, Landi MT, Johansson M, Risch A, Wichmann HE, ... ... Lazarus P, et al. Association analysis of driver-gene related genetic variants identified novel lung cancer susceptibility loci with 20,871 lung cancer cases and 15,971 controls. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 32277007 DOI: 10.1158/1055-9965.Epi-19-1085 |
0.355 |
|
| 2020 |
Borrego-Soto G, Perez-Paramo YX, Chen G, Santuario-Facio SK, Santos-Guzman J, Posadas-Valay R, Alvarado-Monroy FM, Balderas-Renteria I, Medina-Gonzalez R, Ortiz-Lopez R, Lazarus P, Rojas-Martinez A. Genetic variants in CYP2A6 and UGT1A9 genes associated with urinary nicotine metabolites in young Mexican smokers. The Pharmacogenomics Journal. PMID 31959879 DOI: 10.1038/S41397-020-0147-4 |
0.393 |
|
| 2020 |
Perez Paramo YX, Watson CJ, Chen G, Natesan S, Lazarus P. Assessment of CYP2A6 and CYP2C19 Genetic Variation on Cotinine‐
N
‐Oxide Formation and their Potential Effect on the Nicotine Metabolic Ratio (NMR) The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06811 |
0.324 |
|
| 2020 |
Teslenko IL, Chen G, Watson C, Lazarus P. Cytosolic glutathione‐S‐transferase A1 (GSTA1) plays a primary role in the metabolic clearance of the aromatase inhibitor, Exemestane The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05991 |
0.334 |
|
| 2020 |
Nasrin S, Watson CJ, Chen G, Lazarus P. Cannabinoid metabolites as potential inhibitors of major CYP450 enzymes. Implication for cannabis‐drug interactions. The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05863 |
0.303 |
|
| 2019 |
Vergara AG, Watson CJW, Chen G, Lazarus P. UDP-glycosyltransferase 3A (UGT3A) metabolism of polycyclic aromatic hydrocarbons: potential importance in aerodigestive tract tissues. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 31836608 DOI: 10.1124/Dmd.119.089284 |
0.396 |
|
| 2019 |
Lee YA, Al-Temimi M, Ying J, Muscat J, Olshan AF, Zevallos JP, Winn DM, Li G, Sturgis EM, Morgenstern H, Zhang ZF, Smith E, Kelsey K, McClean M, Vaughan TL, ... Lazarus P, et al. Head and Neck Cancer Risk Prediction Models for the US Population from the INHANCE Consortium. American Journal of Epidemiology. PMID 31781743 DOI: 10.1093/Aje/Kwz259 |
0.331 |
|
| 2019 |
Bossé Y, Li Z, Xia J, Manem V, Carreras-Torres R, Gabriel A, Gaudreault N, Albanes D, Aldrich MC, Andrew A, Arnold S, Bickeböller H, Bojesen SE, Brennan P, Brunnstrom H, ... ... Lazarus P, et al. Transcriptome-wide association study reveals candidate causal genes for lung cancer. International Journal of Cancer. PMID 31696517 DOI: 10.1002/Ijc.32771 |
0.369 |
|
| 2019 |
Chang CP, Chang SC, Chuang SC, Berthiller J, Ferro G, Matsuo K, Wünsch-Filho V, Toporcov TN, de Carvalho MB, La Vecchia C, Olshan AF, Zevallos JP, Serraino D, Muscat J, Sturgis EM, ... ... Lazarus P, et al. Age at start of using tobacco on the risk of head and neck cancer: Pooled analysis in the International Head and Neck Cancer Epidemiology Consortium (INHANCE). Cancer Epidemiology. 63: 101615. PMID 31586822 DOI: 10.1016/J.Canep.2019.101615 |
0.325 |
|
| 2019 |
Dai J, Huang M, Amos CI, Hung RJ, Tardon A, Andrew A, Chen C, Christiani DC, Albanes D, Rennert G, Fan J, Goodman G, Liu G, Field JK, Grankvist K, ... ... Lazarus P, et al. Genome-wide association study of INDELs identified four novel susceptibility loci associated with lung cancer risk. International Journal of Cancer. PMID 31577861 DOI: 10.1002/Ijc.32698 |
0.388 |
|
| 2019 |
Kozlovich S, Chen G, Watson CJ, Lazarus P. Prominent Stereo-selectivity of NNAL Glucuronidation in Upper Aerodigestive Tract Tissues. Chemical Research in Toxicology. PMID 31307193 DOI: 10.1021/Acs.Chemrestox.9B00217 |
0.362 |
|
| 2019 |
Di Credico G, Edefonti V, Polesel J, Pauli F, Torelli N, Serraino D, Negri E, Luce D, Stucker I, Matsuo K, Brennan P, Vilensky M, Fernandez L, Curado MP, Menezes A, ... ... Lazarus P, et al. Joint effects of intensity and duration of cigarette smoking on the risk of head and neck cancer: A bivariate spline model approach. Oral Oncology. 94: 47-57. PMID 31178212 DOI: 10.1016/J.Oraloncology.2019.05.006 |
0.311 |
|
| 2019 |
Liu SN, Lu JBL, Watson CJ, Lazarus P, Desta Z, Gufford BT. Mechanistic Assessment of Extrahepatic Contributions to Glucuronidation of Integrase Strand Transfer Inhibitors. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 30804050 DOI: 10.1124/Dmd.118.085035 |
0.313 |
|
| 2019 |
Richardson H, Knight B, Chen G, Luo S, Massey T, Goss P, Lazarus P. Abstract P6-13-05: Association between the UGT2B17 gene deletion, exemestane metabolites and vasomotor QOL in women participating on the MAP3 prevention trial Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P6-13-05 |
0.361 |
|
| 2018 |
Brenner DR, Fehringer G, Zhang ZF, Lee YA, Meyers T, Matsuo K, Ito H, Vineis P, Stucker I, Boffetta P, Brennan P, Christiani DC, Diao N, Hong YC, Landi MT, ... ... Lazarus P, et al. Alcohol consumption and lung cancer risk: A pooled analysis from the International Lung Cancer Consortium and the SYNERGY study. Cancer Epidemiology. 58: 25-32. PMID 30445228 DOI: 10.1016/J.Canep.2018.10.006 |
0.343 |
|
| 2018 |
Perez-Paramo YX, Chen G, Ashmore JH, Watson CJW, Nasrin S, Adams-Haduch J, Wang R, Gao YT, Koh WP, Yuan JM, Lazarus P. Nicotine-N'-oxidation by flavin monooxygenase enzymes. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 30381441 DOI: 10.1158/1055-9965.Epi-18-0669 |
0.344 |
|
| 2018 |
Ferreiro-Iglesias A, Lesseur C, McKay J, Hung RJ, Han Y, Zong X, Christiani D, Johansson M, Xiao X, Li Y, Qian DC, Ji X, Liu G, Caporaso N, Scelo G, ... ... Lazarus P, et al. Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity. Nature Communications. 9: 3927. PMID 30254314 DOI: 10.1038/S41467-018-05890-2 |
0.342 |
|
| 2018 |
Kachuri L, Saarela O, Bojesen SE, Davey Smith G, Liu G, Landi MT, Caporaso NE, Christiani DC, Johansson M, Panico S, Overvad K, Trichopoulou A, Vineis P, Scelo G, Zaridze D, ... ... Lazarus P, et al. Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers. International Journal of Epidemiology. PMID 30059977 DOI: 10.1093/Ije/Dyy140 |
0.348 |
|
| 2018 |
Denton TT, Srivastava P, Xia Z, Chen G, Watson C, Wynd A, Lazarus P. Identification of the 4-position of 3-alkynyl and 3-heteroaromatic substituted pyridine methanamines as a key modification site eliciting increased potency and enhanced selectivity for cytochrome P-450 2A6 inhibition. Journal of Medicinal Chemistry. PMID 29995408 DOI: 10.1021/Acs.Jmedchem.8B00084 |
0.346 |
|
| 2018 |
Ashmore JH, Luo S, Watson CJW, Lazarus P. Carbonyl Reduction of NNK by Recombinant Human Lung Enzymes. Identification of HSD17β12 as the Reductase important in (R)-NNAL formation in Human Lung. Carcinogenesis. PMID 29788210 DOI: 10.1093/Carcin/Bgy065 |
0.36 |
|
| 2018 |
Voltzke KJ, Lee YA, Zhang ZF, Zevallos JP, Yu GP, Winn DM, Vaughan TL, Sturgis EM, Smith E, Schwartz SM, Schantz S, Muscat J, Morgenstern H, McClean M, Li G, ... Lazarus P, et al. Racial differences in the relationship between tobacco, alcohol, and the risk of head and neck cancer: pooled analysis of US studies in the INHANCE Consortium. Cancer Causes & Control : Ccc. PMID 29761303 DOI: 10.1007/S10552-018-1026-Z |
0.34 |
|
| 2017 |
Peterson A, Xia Z, Chen G, Lazarus P. In vitro metabolism of exemestane by hepatic cytochrome P450s: impact of nonsynonymous polymorphisms on formation of the active metabolite 17β-dihydroexemestane. Pharmacology Research & Perspectives. 5: e00314. PMID 28603633 DOI: 10.1002/Prp2.314 |
0.393 |
|
| 2017 |
Peterson A, Xia Z, Chen G, Lazarus P. Exemestane potency is unchanged by common nonsynonymous polymorphisms in CYP19A1: results of a novel anti-aromatase activity assay examining exemestane and its derivatives. Pharmacology Research & Perspectives. 5: e00313. PMID 28603632 DOI: 10.1002/Prp2.313 |
0.331 |
|
| 2017 |
Fehringer G, Brenner DR, Zhang ZF, Lee YA, Matsuo K, Ito H, Lan Q, Vineis P, Johansson M, Overvad K, Riboli E, Trichopoulou A, Sacerdote C, Stucker I, Boffetta P, ... ... Lazarus P, et al. Alcohol and Lung Cancer Risk Among Never Smokers: A Pooled Analysis from the International Lung Cancer Consortium and the SYNERGY Study. International Journal of Cancer. PMID 28120396 DOI: 10.1002/Ijc.30618 |
0.361 |
|
| 2017 |
Kachuri L, Johansson M, Brennan P, Haycock P, Liu G, Landi MT, Christiani DC, Caporaso NE, Wu X, Aldrich MC, Albanes D, Tardón A, Rennert G, Chen C, Goodman GE, ... ... Lazarus P, et al. Abstract 2292: Lung function and lung cancer risk: a Mendelian randomization study of UK Biobank cohort and the International Lung Cancer Consortium Epidemiology. 77: 2292-2292. DOI: 10.1158/1538-7445.Am2017-2292 |
0.317 |
|
| 2016 |
Chen LS, Baker T, Hung RJ, Horton A, Culverhouse R, Hartz S, Saccone N, Cheng I, Deng B, Han Y, Hansen HM, Horsman J, Kim C, Rosenberger A, Aben KK, ... ... Lazarus P, et al. Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes - A Meta-Analysis. Ebiomedicine. 11: 219-226. PMID 27543155 DOI: 10.1016/J.Ebiom.2016.08.012 |
0.367 |
|
| 2016 |
Chen G, Luo S, Kozlovich S, Lazarus P. Association between glucuronidation genotypes and urinary NNAL metabolic phenotypes in smokers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 27197298 DOI: 10.1158/1055-9965.Epi-15-1245 |
0.387 |
|
| 2016 |
Platt A, Xia Z, Liu Y, Chen G, Lazarus P. Impact of nonsynonymous single nucleotide polymorphisms on in-vitro metabolism of exemestane by hepatic cytosolic reductases. Pharmacogenetics and Genomics. PMID 27111237 DOI: 10.1097/Fpc.0000000000000226 |
0.396 |
|
| 2016 |
Kachuri L, Smith GD, Liu G, Landi MT, Christiani DC, Caporaso NE, McKay JD, Wu X, Aldrich MC, Rennert G, Teare D, Chen C, Goodman GE, Doherty JA, Field JK, ... ... Lazarus P, et al. Abstract 817: Mendelian randomization and mediation analysis of 5p15.33, telomere length and lung cancer risk Cancer Research. 76: 817-817. DOI: 10.1158/1538-7445.Am2016-817 |
0.393 |
|
| 2015 |
Huang R, Wei Y, Hung RJ, Liu G, Su L, Zhang R, Zong X, Zhang ZF, Morgenstern H, Brüske I, Heinrich J, Hong YC, Kim JH, Cote M, Wenzlaff A, ... ... Lazarus P, et al. Associated Links Among Smoking, Chronic Obstructive Pulmonary Disease, and Small Cell Lung Cancer: A Pooled Analysis in the International Lung Cancer Consortium. Ebiomedicine. 2: 1677-1685. PMID 26870794 DOI: 10.1016/J.Ebiom.2015.09.031 |
0.336 |
|
| 2015 |
Jones NR, Ashmore JH, Lee SY, Richie JP, Lazarus P, Muscat JE. Association Studies of HFE C282Y and H63D Variants with Oral Cancer Risk and Iron Homeostasis Among Whites and Blacks. Cancers. 7: 2386-96. PMID 26690219 DOI: 10.3390/Cancers7040898 |
0.307 |
|
| 2015 |
Kozlovich S, Chen G, Lazarus P. Stereospecific Metabolism of the Tobacco Specific Nitrosamine, NNAL. Chemical Research in Toxicology. PMID 26452127 DOI: 10.1021/Acs.Chemrestox.5B00278 |
0.346 |
|
| 2015 |
Berthiller J, Straif K, Agudo A, Ahrens W, Bezerra Dos Santos A, Boccia S, Cadoni G, Canova C, Castellsague X, Chen C, Conway D, Curado MP, Dal Maso L, Daudt AW, Fabianova E, ... ... Lazarus P, et al. Low frequency of cigarette smoking and the risk of head and neck cancer in the INHANCE consortium pooled analysis. International Journal of Epidemiology. PMID 26228584 DOI: 10.1093/Ije/Dyv146 |
0.32 |
|
| 2015 |
Gufford BT, Chen G, Vergara AG, Lazarus P, Oberlies NH, Paine MF. Milk Thistle Constituents Inhibit Raloxifene Intestinal Glucuronidation: A Potential Clinically Relevant Natural Product-Drug Interaction. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 1353-9. PMID 26070840 DOI: 10.1124/Dmd.115.065086 |
0.305 |
|
| 2015 |
Chen LS, Hung RJ, Baker T, Horton A, Culverhouse R, Saccone N, Cheng I, Deng B, Han Y, Hansen HM, Horsman J, Kim C, Lutz S, Rosenberger A, Aben KK, ... ... Lazarus P, et al. CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis. Journal of the National Cancer Institute. 107. PMID 25873736 DOI: 10.1093/Jnci/Djv100 |
0.368 |
|
| 2015 |
Conway DI, Brenner DR, McMahon AD, Macpherson LM, Agudo A, Ahrens W, Bosetti C, Brenner H, Castellsague X, Chen C, Curado MP, Curioni OA, Dal Maso L, Daudt AW, de Gois Filho JF, ... ... Lazarus P, et al. Estimating and explaining the effect of education and income on head and neck cancer risk: INHANCE consortium pooled analysis of 31 case-control studies from 27 countries. International Journal of Cancer. Journal International Du Cancer. 136: 1125-39. PMID 24996155 DOI: 10.1002/Ijc.29063 |
0.347 |
|
| 2015 |
Modesto JL, Hull A, Angstadt AY, Berg A, Gallagher CJ, Lazarus P, Muscat JE. NNK reduction pathway gene polymorphisms and risk of lung cancer. Molecular Carcinogenesis. 54: E94-E102. PMID 24976539 DOI: 10.1002/Mc.22187 |
0.428 |
|
| 2015 |
Zhang LR, Morgenstern H, Greenland S, Chang SC, Lazarus P, Teare MD, Woll PJ, Orlow I, Cox B, Brhane Y, Liu G, Hung RJ. Cannabis smoking and lung cancer risk: Pooled analysis in the International Lung Cancer Consortium. International Journal of Cancer. Journal International Du Cancer. 136: 894-903. PMID 24947688 DOI: 10.1002/Ijc.29036 |
0.382 |
|
| 2015 |
Ashmore J, Liu Y, Peterson A, Fechtner S, Chen G, Lazarus P. Abstract 2722: Characterization of human lung enzymes involved in the reduction of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) Cancer Research. 75: 2722-2722. DOI: 10.1158/1538-7445.Am2015-2722 |
0.374 |
|
| 2014 |
Menvielle G, Truong T, Jellouli F, Stücker I, Brenner H, Field JK, Hosgood HD, Lan Q, Landi MT, Hung RJ, Lazarus P, McLaughlin J, Morgenstern H, Muscat JE, Ruano-Ravina A, et al. Education and lung cancer among never smokers. Epidemiology (Cambridge, Mass.). 25: 934-5. PMID 25265142 DOI: 10.1097/Ede.0000000000000183 |
0.366 |
|
| 2014 |
Angstadt AY, Hartman TJ, Lesko SM, Muscat JE, Zhu J, Gallagher CJ, Lazarus P. The effect of UGT1A and UGT2B polymorphisms on colorectal cancer risk: haplotype associations and gene–environment interactions. Genes, Chromosomes & Cancer. 53: 454-66. PMID 24822274 DOI: 10.1002/Gcc.22157 |
0.375 |
|
| 2014 |
Kim CH, Lee YC, Hung RJ, McNallan SR, Cote ML, Lim WY, Chang SC, Kim JH, Ugolini D, Chen Y, Liloglou T, Andrew AS, Onega T, Duell EJ, Field JK, ... Lazarus P, et al. Exposure to secondhand tobacco smoke and lung cancer by histological type: a pooled analysis of the International Lung Cancer Consortium (ILCCO). International Journal of Cancer. Journal International Du Cancer. 135: 1918-30. PMID 24615328 DOI: 10.1002/Ijc.28835 |
0.364 |
|
| 2014 |
Jones NR, Lazarus P. UGT2B gene expression analysis in multiple tobacco carcinogen-targeted tissues. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 529-36. PMID 24459179 DOI: 10.1124/Dmd.113.054718 |
0.349 |
|
| 2014 |
Dluzen DF, Sun D, Salzberg AC, Jones N, Bushey RT, Robertson GP, Lazarus P. Regulation of UDP-glucuronosyltransferase 1A1 expression and activity by microRNA 491-3p. The Journal of Pharmacology and Experimental Therapeutics. 348: 465-77. PMID 24399855 DOI: 10.1124/Jpet.113.210658 |
0.302 |
|
| 2014 |
Marks MA, Chaturvedi AK, Kelsey K, Straif K, Berthiller J, Schwartz SM, Smith E, Wyss A, Brennan P, Olshan AF, Wei Q, Sturgis EM, Zhang ZF, Morgenstern H, Muscat J, ... Lazarus P, et al. Association of marijuana smoking with oropharyngeal and oral tongue cancers: pooled analysis from the INHANCE consortium. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 23: 160-71. PMID 24351902 DOI: 10.1158/1055-9965.Epi-13-0181 |
0.373 |
|
| 2014 |
Leoncini E, Ricciardi W, Cadoni G, Arzani D, Petrelli L, Paludetti G, Brennan P, Luce D, Stucker I, Matsuo K, Talamini R, La Vecchia C, Olshan AF, Winn DM, Herrero R, ... ... Lazarus P, et al. Adult height and head and neck cancer: a pooled analysis within the INHANCE Consortium. European Journal of Epidemiology. 29: 35-48. PMID 24271556 DOI: 10.1007/S10654-013-9863-2 |
0.366 |
|
| 2014 |
Fehringer G, Brenner D, Zhang Z, Lee YA, Matsuo K, Stucker I, Vineis P, Boffetta P, Brennan P, Landi MT, Morgenstern H, Harris CC, Lan Q, Hong Y, Siemiatycki J, ... ... Lazarus P, et al. Abstract 1274: Alcohol and lung cancer risk: a pooled analysis using International Lung Cancer Consortium studies Cancer Research. 74: 1274-1274. DOI: 10.1158/1538-7445.Am2014-1274 |
0.355 |
|
| 2013 |
Baldwin DA, Sarnowski CP, Reddy SA, Blair IA, Clapper M, Lazarus P, Li M, Muscat JE, Penning TM, Vachani A, Whitehead AS. Development of a genotyping microarray for studying the role of gene-environment interactions in risk for lung cancer. Journal of Biomolecular Techniques : Jbt. 24: 198-217. PMID 24294113 DOI: 10.7171/Jbt.13-2404-004 |
0.379 |
|
| 2013 |
Ashmore JH, Lesko SM, Muscat JE, Gallagher CJ, Berg AS, Miller PE, Hartman TJ, Lazarus P. Association of dietary and supplemental folate intake and polymorphisms in three FOCM pathway genes with colorectal cancer in a population-based case-control study. Genes, Chromosomes & Cancer. 52: 945-53. PMID 23893618 DOI: 10.1002/Gcc.22089 |
0.374 |
|
| 2013 |
Wyss A, Hashibe M, Chuang SC, Lee YC, Zhang ZF, Yu GP, Winn DM, Wei Q, Talamini R, Szeszenia-Dabrowska N, Sturgis EM, Smith E, Shangina O, Schwartz SM, Schantz S, ... ... Lazarus P, et al. Cigarette, cigar, and pipe smoking and the risk of head and neck cancers: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. American Journal of Epidemiology. 178: 679-90. PMID 23817919 DOI: 10.1093/Aje/Kwt029 |
0.324 |
|
| 2013 |
Sun D, Jones NR, Manni A, Lazarus P. Characterization of raloxifene glucuronidation: potential role of UGT1A8 genotype on raloxifene metabolism in vivo. Cancer Prevention Research (Philadelphia, Pa.). 6: 719-30. PMID 23682072 DOI: 10.1158/1940-6207.Capr-12-0448 |
0.444 |
|
| 2013 |
Angstadt AY, Berg A, Zhu J, Miller P, Hartman TJ, Lesko SM, Muscat JE, Lazarus P, Gallagher CJ. The effect of copy number variation in the phase II detoxification genes UGT2B17 and UGT2B28 on colorectal cancer risk. Cancer. 119: 2477-85. PMID 23575887 DOI: 10.1002/Cncr.28009 |
0.383 |
|
| 2013 |
Miller PE, Lazarus P, Lesko SM, Cross AJ, Sinha R, Laio J, Zhu J, Harper G, Muscat JE, Hartman TJ. Meat-related compounds and colorectal cancer risk by anatomical subsite. Nutrition and Cancer. 65: 202-26. PMID 23441608 DOI: 10.1080/01635581.2013.756534 |
0.329 |
|
| 2013 |
Bushey RT, Dluzen DF, Lazarus P. Importance of UDP-glucuronosyltransferases 2A2 and 2A3 in tobacco carcinogen metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 170-9. PMID 23086198 DOI: 10.1124/Dmd.112.049171 |
0.428 |
|
| 2013 |
Nichenametla SN, Muscat JE, Liao JG, Lazarus P, Richie JP. A functional trinucleotide repeat polymorphism in the 5'-untranslated region of the glutathione biosynthetic gene GCLC is associated with increased risk for lung and aerodigestive tract cancers. Molecular Carcinogenesis. 52: 791-9. PMID 22610501 DOI: 10.1002/Mc.21923 |
0.428 |
|
| 2013 |
Zhang LR, Zhang Z, Morgenstern H, Chang S, Lazarus P, Teare MD, Woll PJ, Orlow I, Cox B, Liu G, Hung RJ. Abstract 3633: Cannabis smoking and lung cancer risk: pooled analysis in the International Lung Cancer Consortium. Cancer Research. 73: 3633-3633. DOI: 10.1158/1538-7445.Am2013-3633 |
0.383 |
|
| 2013 |
Dluzen DF, Salzberg A, Sun D, Jones N, Bushey R, Lazarus P. Abstract 3089: miR-491-3p regulation of the UDP-glucuronosyltransferase (UGT) 1A gene family. Cancer Research. 73: 3089-3089. DOI: 10.1158/1538-7445.Am2013-3089 |
0.323 |
|
| 2013 |
Bushey RT, Chen G, Lazarus P. Abstract 2563: Identification and functional characterization of a novel UGT2A1 splice variant: Potential importance in tobacco-related cancer susceptibility . Cancer Research. 73: 2563-2563. DOI: 10.1158/1538-7445.Am2013-2563 |
0.417 |
|
| 2013 |
Sun D, Jones NR, Andrea M, Lazarus P. Abstract 2203: Characterization of raloxifene glucuronidation and the role of UGT genotypes on raloxifene metabolite profilesin vivo. Cancer Research. 73: 2203-2203. DOI: 10.1158/1538-7445.Am2013-2203 |
0.46 |
|
| 2012 |
Brenner DR, Boffetta P, Duell EJ, Bickeböller H, Rosenberger A, McCormack V, Muscat JE, Yang P, Wichmann HE, Brueske-Hohlfeld I, Schwartz AG, Cote ML, Tjønneland A, Friis S, Le Marchand L, ... ... Lazarus P, et al. Previous lung diseases and lung cancer risk: a pooled analysis from the International Lung Cancer Consortium. American Journal of Epidemiology. 176: 573-85. PMID 22986146 DOI: 10.1093/Aje/Kws151 |
0.358 |
|
| 2012 |
Bushey RT, Lazarus P. Identification and functional characterization of a novel UDP-glucuronosyltransferase 2A1 splice variant: potential importance in tobacco-related cancer susceptibility. The Journal of Pharmacology and Experimental Therapeutics. 343: 712-24. PMID 22984225 DOI: 10.1124/Jpet.112.198770 |
0.422 |
|
| 2012 |
Jones NR, Sun D, Freeman WM, Lazarus P. Quantification of Hepatic UDP glucuronosyltransferase 1A splice variant expression and correlation of UDP glucuronosyltransferase 1A1 variant expression with glucuronidation activity. The Journal of Pharmacology and Experimental Therapeutics. 342: 720-9. PMID 22661630 DOI: 10.1124/Jpet.112.192658 |
0.315 |
|
| 2012 |
Erickson-Ridout KK, Sun D, Lazarus P. Glucuronidation of the second-generation antipsychotic clozapine and its active metabolite N-desmethylclozapine. Potential importance of the UGT1A1 A(TA)₇TAA and UGT1A4 L48V polymorphisms. Pharmacogenetics and Genomics. 22: 561-76. PMID 22565219 DOI: 10.1097/Fpc.0B013E328354026B |
0.734 |
|
| 2012 |
Coté ML, Liu M, Bonassi S, Neri M, Schwartz AG, Christiani DC, Spitz MR, Muscat JE, Rennert G, Aben KK, Andrew AS, Bencko V, Bickeböller H, Boffetta P, Brennan P, ... ... Lazarus P, et al. Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium. European Journal of Cancer (Oxford, England : 1990). 48: 1957-68. PMID 22436981 DOI: 10.1016/J.Ejca.2012.01.038 |
0.377 |
|
| 2012 |
Chen G, Giambrone NE, Lazarus P. Glucuronidation of trans-3'-hydroxycotinine by UGT2B17 and UGT2B10. Pharmacogenetics and Genomics. 22: 183-90. PMID 22228205 DOI: 10.1097/Fpc.0B013E32834Ff3A5 |
0.369 |
|
| 2012 |
Li Q, Chuang SC, Eluf-Neto J, Menezes A, Matos E, Koifman S, Wünsch-Filho V, Fernandez L, Daudt AW, Curado MP, Winn DM, Franceschi S, Herrero R, Castellsague X, Morgenstern H, ... ... Lazarus P, et al. Vitamin or mineral supplement intake and the risk of head and neck cancer: pooled analysis in the INHANCE consortium. International Journal of Cancer. Journal International Du Cancer. 131: 1686-99. PMID 22173631 DOI: 10.1002/Ijc.27405 |
0.315 |
|
| 2012 |
Stott-Miller M, Chen C, Chuang SC, Lee YC, Boccia S, Brenner H, Cadoni G, Dal Maso L, La Vecchia C, Lazarus P, Levi F, Matsuo K, Morgenstern H, Müller H, Muscat J, et al. History of diabetes and risk of head and neck cancer: a pooled analysis from the international head and neck cancer epidemiology consortium. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 21: 294-304. PMID 22144496 DOI: 10.1158/1055-9965.Epi-11-0590 |
0.342 |
|
| 2012 |
Chuang SC, Jenab M, Heck JE, Bosetti C, Talamini R, Matsuo K, Castellsague X, Franceschi S, Herrero R, Winn DM, La Vecchia C, Morgenstern H, Zhang ZF, Levi F, Dal Maso L, ... ... Lazarus P, et al. Diet and the risk of head and neck cancer: a pooled analysis in the INHANCE consortium. Cancer Causes & Control : Ccc. 23: 69-88. PMID 22037906 DOI: 10.1007/S10552-011-9857-X |
0.315 |
|
| 2012 |
Miller PE, Lazarus P, Lesko SM, Cross AJ, Sinha R, Laio J, Zhu J, Harper G, Muscat JE, Hartman TJ. Abstract 4460A: Meat-related compounds and colorectal cancer risk by anatomical subsite Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-4460A |
0.37 |
|
| 2011 |
Chuang SC, Agudo A, Ahrens W, Anantharaman D, Benhamou S, Boccia S, Chen C, Conway DI, Fabianova E, Hayes RB, Healy CM, Holcatova I, Kjaerheim K, Lagiou P, Lazarus P, et al. Sequence Variants and the Risk of Head and Neck Cancer: Pooled Analysis in the INHANCE Consortium. Frontiers in Oncology. 1: 13. PMID 22655231 DOI: 10.3389/Fonc.2011.00013 |
0.385 |
|
| 2011 |
McCormack VA, Hung RJ, Brenner DR, Bickeböller H, Rosenberger A, Muscat JE, Lazarus P, Tjønneland A, Friis S, Christiani DC, Chun EM, Le Marchand L, Rennert G, Rennert HS, Andrew AS, et al. Aspirin and NSAID use and lung cancer risk: a pooled analysis in the International Lung Cancer Consortium (ILCCO). Cancer Causes & Control : Ccc. 22: 1709-20. PMID 21987079 DOI: 10.1007/S10552-011-9847-Z |
0.333 |
|
| 2011 |
Crampsie MA, Jones N, Das A, Aliaga C, Desai D, Lazarus P, Amin S, Sharma AK. Phenylbutyl isoselenocyanate modulates phase I and II enzymes and inhibits 4-(methylnitrosamino)-1-(3-pyridyl)- 1-butanone-induced DNA adducts in mice. Cancer Prevention Research (Philadelphia, Pa.). 4: 1884-94. PMID 21795424 DOI: 10.1158/1940-6207.Capr-11-0221 |
0.376 |
|
| 2011 |
Olson KC, Sun D, Chen G, Sharma AK, Amin S, Ropson IJ, Spratt TE, Lazarus P. Characterization of dibenzo[a,l]pyrene-trans-11,12-diol (dibenzo[def,p]chrysene) glucuronidation by UDP-glucuronosyltransferases. Chemical Research in Toxicology. 24: 1549-59. PMID 21780761 DOI: 10.1021/Tx200178V |
0.302 |
|
| 2011 |
Erickson-Ridout KK, Zhu J, Lazarus P. Olanzapine metabolism and the significance of UGT1A448V and UGT2B1067Y variants. Pharmacogenetics and Genomics. 21: 539-51. PMID 21750471 DOI: 10.1097/Fpc.0B013E328348C76B |
0.724 |
|
| 2011 |
Lubin JH, Muscat J, Gaudet MM, Olshan AF, Curado MP, Dal Maso L, Wünsch-Filho V, Sturgis EM, Szeszenia-Dabrowska N, Castellsague X, Zhang ZF, Smith E, Fernandez L, Matos E, Franceschi S, ... ... Lazarus P, et al. An examination of male and female odds ratios by BMI, cigarette smoking, and alcohol consumption for cancers of the oral cavity, pharynx, and larynx in pooled data from 15 case-control studies. Cancer Causes & Control : Ccc. 22: 1217-31. PMID 21744095 DOI: 10.1007/S10552-011-9792-X |
0.358 |
|
| 2011 |
Nichenametla SN, Lazarus P, Richie JP. A GAG trinucleotide-repeat polymorphism in the gene for glutathione biosynthetic enzyme, GCLC, affects gene expression through translation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2180-7. PMID 21444626 DOI: 10.1096/Fj.10-174011 |
0.379 |
|
| 2011 |
McKay JD, Truong T, Gaborieau V, Chabrier A, Chuang SC, Byrnes G, Zaridze D, Shangina O, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Bucur A, Bencko V, Holcatova I, ... ... Lazarus P, et al. A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. Plos Genetics. 7: e1001333. PMID 21437268 DOI: 10.1371/Journal.Pgen.1001333 |
0.384 |
|
| 2011 |
Chen D, Truong T, Gaborieau V, Byrnes G, Chabrier A, Chuang SC, Olshan AF, Weissler MC, Luo J, Romkes M, Buch S, Nukui T, Franceschi S, Herrero R, Talamini R, ... ... Lazarus P, et al. A sex-specific association between a 15q25 variant and upper aerodigestive tract cancers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 20: 658-64. PMID 21335511 DOI: 10.1158/1055-9965.Epi-10-1008 |
0.407 |
|
| 2011 |
Bushey RT, Chen G, Blevins-Primeau AS, Krzeminski J, Amin S, Lazarus P. Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis. Pharmacogenetics and Genomics. 21: 55-65. PMID 21164388 DOI: 10.1097/Fpc.0B013E328341Db05 |
0.416 |
|
| 2011 |
Jones NR, Spratt TE, Berg AS, Muscat JE, Lazarus P, Gallagher CJ. Association studies of excision repair cross-complementation group 1 (ERCC1) haplotypes with lung and head and neck cancer risk in a Caucasian population. Cancer Epidemiology. 35: 175-81. PMID 20863778 DOI: 10.1016/J.Canep.2010.08.007 |
0.352 |
|
| 2011 |
Sun D, Liu Y, McCloskey DE, Lazarus P. Abstract 712: Characterization of exemestane metabolic pathways Cancer Research. 71: 712-712. DOI: 10.1158/1538-7445.Am2011-712 |
0.411 |
|
| 2011 |
Chen G, Giambrone NE, Muscat JE, Lazarus P. Abstract 2757: Characterization of the glucuronidation of the major nicotine metabolite, 3’-hydroxycotinine: Potential role for knock-out polymorphisms in UGTs 2B17 and 2B10 Cancer Research. 71: 2757-2757. DOI: 10.1158/1538-7445.Am2011-2757 |
0.386 |
|
| 2010 |
Chen G, Giambrone NE, Dluzen DF, Muscat JE, Berg A, Gallagher CJ, Lazarus P. Glucuronidation genotypes and nicotine metabolic phenotypes: importance of functional UGT2B10 and UGT2B17 polymorphisms. Cancer Research. 70: 7543-52. PMID 20876810 DOI: 10.1158/0008-5472.Can-09-4582 |
0.379 |
|
| 2010 |
Gallagher CJ, Balliet RM, Sun D, Chen G, Lazarus P. Sex differences in UDP-glucuronosyltransferase 2B17 expression and activity. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 2204-9. PMID 20810538 DOI: 10.1124/Dmd.110.035345 |
0.761 |
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| 2010 |
Sun D, Chen G, Dellinger RW, Sharma AK, Lazarus P. Characterization of 17-dihydroexemestane glucuronidation: potential role of the UGT2B17 deletion in exemestane pharmacogenetics. Pharmacogenetics and Genomics. 20: 575-85. PMID 20697310 DOI: 10.1097/Fpc.0B013E32833B04Af |
0.396 |
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| 2010 |
Mikse OR, Blake DC, Jones NR, Sun YW, Amin S, Gallagher CJ, Lazarus P, Weisz J, Herzog CR. FOXO3 encodes a carcinogen-activated transcription factor frequently deleted in early-stage lung adenocarcinoma. Cancer Research. 70: 6205-15. PMID 20631076 DOI: 10.1158/0008-5472.Can-09-4008 |
0.346 |
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| 2010 |
Lubin JH, Gaudet MM, Olshan AF, Kelsey K, Boffetta P, Brennan P, Castellsague X, Chen C, Curado MP, Dal Maso L, Daudt AW, Fabianova E, Fernandez L, Wünsch-Filho V, Franceschi S, ... ... Lazarus P, et al. Body mass index, cigarette smoking, and alcohol consumption and cancers of the oral cavity, pharynx, and larynx: modeling odds ratios in pooled case-control data. American Journal of Epidemiology. 171: 1250-61. PMID 20494999 DOI: 10.1093/Aje/Kwq088 |
0.355 |
|
| 2010 |
Li Y, Ma C, Wang Z, Chen G, Ahn K, Lazarus P, Wu R. A disequilibrium model for detecting genetic mutations for cancer Journal of Theoretical Biology. 265: 218-224. PMID 20450921 DOI: 10.1016/J.Jtbi.2010.04.019 |
0.339 |
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| 2010 |
Miller PE, Lazarus P, Lesko SM, Muscat JE, Harper G, Cross AJ, Sinha R, Ryczak K, Escobar G, Mauger DT, Hartman TJ. Diet index-based and empirically derived dietary patterns are associated with colorectal cancer risk. The Journal of Nutrition. 140: 1267-73. PMID 20444952 DOI: 10.3945/Jn.110.121780 |
0.32 |
|
| 2010 |
Miller PE, Lesko SM, Muscat JE, Lazarus P, Hartman TJ. Dietary patterns and colorectal adenoma and cancer risk: a review of the epidemiological evidence. Nutrition and Cancer. 62: 413-24. PMID 20432162 DOI: 10.1080/01635580903407114 |
0.318 |
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| 2010 |
Gaudet MM, Olshan AF, Chuang SC, Berthiller J, Zhang ZF, Lissowska J, Zaridze D, Winn DM, Wei Q, Talamini R, Szeszenia-Dabrowska N, Sturgis EM, Schwartz SM, Rudnai P, Eluf-Neto J, ... ... Lazarus P, et al. Body mass index and risk of head and neck cancer in a pooled analysis of case-control studies in the International Head and Neck Cancer Epidemiology (INHANCE) Consortium. International Journal of Epidemiology. 39: 1091-102. PMID 20123951 DOI: 10.1093/Ije/Dyp380 |
0.335 |
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| 2010 |
Truong T, Sauter W, McKay JD, Hosgood HD, Gallagher C, Amos CI, Spitz M, Muscat J, Lazarus P, Illig T, Wichmann HE, Bickeböller H, Risch A, Dienemann H, Zhang ZF, et al. International Lung Cancer Consortium: coordinated association study of 10 potential lung cancer susceptibility variants. Carcinogenesis. 31: 625-33. PMID 20106900 DOI: 10.1093/Carcin/Bgq001 |
0.416 |
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| 2010 |
Balliet RM, Chen G, Dellinger RW, Lazarus P. UDP-glucuronosyltransferase 1A10: activity against the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a potential role for a novel UGT1A10 promoter deletion polymorphism in cancer susceptibility. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 484-90. PMID 20007297 DOI: 10.1124/Dmd.109.030569 |
0.78 |
|
| 2010 |
Lazarus P, Sun D. Potential role of UGT pharmacogenetics in cancer treatment and prevention: focus on tamoxifen and aromatase inhibitors. Drug Metabolism Reviews. 42: 182-94. PMID 19821643 DOI: 10.3109/03602530903208652 |
0.327 |
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| 2010 |
Marron M, Boffetta P, Zhang ZF, Zaridze D, Wünsch-Filho V, Winn DM, Wei Q, Talamini R, Szeszenia-Dabrowska N, Sturgis EM, Smith E, Schwartz SM, Rudnai P, Purdue MP, Olshan AF, ... ... Lazarus P, et al. Cessation of alcohol drinking, tobacco smoking and the reversal of head and neck cancer risk. International Journal of Epidemiology. 39: 182-96. PMID 19805488 DOI: 10.1093/Ije/Dyp291 |
0.344 |
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| 2010 |
Miller PE, Lazarus P, Lesko SM, Muscat JE, Harper G, Cross AJ, Sinha R, Liao J, Ashmore JH, Hartman TJ. Abstract A84: Red and processed meat-derived mutagen exposure and colorectal cancer risk in a population-based case-control study Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-A84 |
0.372 |
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| 2010 |
Chen G, Giambrone NE, Dluzen D, Blevins-Primeau AS, Gallagher C, McCloskey D, Lazarus P. Abstract 918: Glucuronidation genotypes and nicotine metabolic phenotypes: Importance of UGT2B10 and UGT2B17 knock-out polymorphisms Cancer Research. 70: 7543. DOI: 10.1158/1538-7445.Am10-918 |
0.385 |
|
| 2010 |
Brenner DR, Boffetta P, Duell EJ, Bickeböller H, Rosenberger A, Muscat JE, Yang P, Wichmann E, Schwartz AG, Tjønneland A, Friis S, LeMarchand L, Zhang Z, Lazarus P, Field JK, et al. Abstract 4826: International Lung Cancer Consortium: Pooled analysis of previous lung diseases and lung cancer risk Cancer Research. 70: 4826-4826. DOI: 10.1158/1538-7445.Am10-4826 |
0.378 |
|
| 2010 |
Sun D, Chen G, Dellinger RW, Sharma AK, Lazarus P. Abstract 3589: Characterization of 17-dihydroexemestane glucuronidation. A role for the UGT2B17 deletion in exemestane pharmacogenetics Cancer Research. 70: 3589-3589. DOI: 10.1158/1538-7445.Am10-3589 |
0.408 |
|
| 2010 |
Olson KC, Sun D, Chen G, Sharma AK, Amin S, Ropson IJ, Spratt TE, Lazarus P. Abstract 3456: Characterization of dibenzo[a,l]pyrene-trans-11,12-diol glucuronidation by UDP-glucuronosyltransferases Cancer Research. 70: 3456-3456. DOI: 10.1158/1538-7445.Am10-3456 |
0.393 |
|
| 2010 |
Jones NR, Chen G, Lazarus P. Abstract 2958: Quantitative and correlative analysis of variant UGT1A mRNA expression in human liver Cancer Research. 70: 2958-2958. DOI: 10.1158/1538-7445.Am10-2958 |
0.364 |
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| 2010 |
Miller PE, Lazarus P, Lesko SM, Muscat JE, Harper G, Cross AJ, Sinha R, Ryczak K, Escobar G, Hartman TJ. Abstract 2828: Examination of two approaches to assess dietary patterns in relation to colorectal cancer risk Cancer Research. 70: 2828-2828. DOI: 10.1158/1538-7445.Am10-2828 |
0.315 |
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| 2010 |
Li Q, Chuang S, Neto JE, Menezes A, Matos E, Koifman S, Wunsch-Filho V, Fernandez L, Daudt AW, Curado MP, Winn DM, Franceschi S, Herrero R, Castellsague X, Zhang Z, ... Lazarus P, et al. Abstract 2818: Vitamin or mineral supplement intake and the risk of head and neck cancer: Pooled analysis in the INHANCE consortium Cancer Research. 70: 2818-2818. DOI: 10.1158/1538-7445.Am10-2818 |
0.319 |
|
| 2010 |
Bushey R, Chen G, Blevins-Primeau AS, Lazarus P. Abstract 1698: Characterization of the activity and expression of UDP-Glucuronosyltransferase 2A1 variants and potential role in tobacco carcinogenesis Cancer Research. 70: 1698-1698. DOI: 10.1158/1538-7445.Am10-1698 |
0.459 |
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| 2010 |
Erickson KK, Lazarus P. Abstract 1680: Characterization of olanzapine glucuronidation: Potential role of the UGT2B10 codon 67 SNP in olanzapine metabolism Cancer Research. 70: 1680-1680. DOI: 10.1158/1538-7445.Am10-1680 |
0.464 |
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| 2009 |
Olson KC, Dellinger RW, Zhong Q, Sun D, Amin S, Spratt TE, Lazarus P. Functional characterization of low-prevalence missense polymorphisms in the UDP-glucuronosyltransferase 1A9 gene. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 1999-2007. PMID 19589876 DOI: 10.1124/Dmd.108.024596 |
0.394 |
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| 2009 |
Berthiller J, Lee YC, Boffetta P, Wei Q, Sturgis EM, Greenland S, Morgenstern H, Zhang ZF, Lazarus P, Muscat J, Chen C, Schwartz SM, Eluf Neto J, Wünsch Filho V, Koifman S, et al. Marijuana smoking and the risk of head and neck cancer: pooled analysis in the INHANCE consortium. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 1544-51. PMID 19423532 DOI: 10.1158/1055-9965.Epi-08-0845 |
0.329 |
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| 2009 |
Yang X, Liang SH, Weyant DM, Lazarus P, Gallagher CJ, Omiecinski CJ. The expression of human microsomal epoxide hydrolase is predominantly driven by a genetically polymorphic far upstream promoter. The Journal of Pharmacology and Experimental Therapeutics. 330: 23-30. PMID 19364907 DOI: 10.1124/Jpet.109.150870 |
0.325 |
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| 2009 |
Balliet RM, Chen G, Gallagher CJ, Dellinger RW, Sun D, Lazarus P. Characterization of UGTs active against SAHA and association between SAHA glucuronidation activity phenotype with UGT genotype. Cancer Research. 69: 2981-9. PMID 19318555 DOI: 10.1158/0008-5472.Can-08-4143 |
0.779 |
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| 2009 |
Lazarus P, Blevins-Primeau AS, Zheng Y, Sun D. Potential role of UGT pharmacogenetics in cancer treatment and prevention: focus on tamoxifen. Annals of the New York Academy of Sciences. 1155: 99-111. PMID 19250197 DOI: 10.1111/J.1749-6632.2009.04114.X |
0.331 |
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| 2009 |
Blevins-Primeau AS, Sun D, Chen G, Sharma AK, Gallagher CJ, Amin S, Lazarus P. Functional significance of UDP-glucuronosyltransferase variants in the metabolism of active tamoxifen metabolites. Cancer Research. 69: 1892-900. PMID 19244109 DOI: 10.1158/0008-5472.Can-08-3708 |
0.465 |
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| 2009 |
Hashibe M, Brennan P, Chuang SC, Boccia S, Castellsague X, Chen C, Curado MP, Dal Maso L, Daudt AW, Fabianova E, Fernandez L, Wünsch-Filho V, Franceschi S, Hayes RB, Herrero R, ... ... Lazarus P, et al. Interaction between tobacco and alcohol use and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 541-50. PMID 19190158 DOI: 10.1158/1055-9965.Epi-08-0347 |
0.337 |
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| 2009 |
Muscat JE, Chen G, Knipe A, Stellman SD, Lazarus P, Richie JP. Effects of menthol on tobacco smoke exposure, nicotine dependence, and NNAL glucuronidation. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 35-41. PMID 19124478 DOI: 10.1158/1055-9965.Epi-08-0744 |
0.367 |
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| 2009 |
Purdue MP, Hashibe M, Berthiller J, La Vecchia C, Dal Maso L, Herrero R, Franceschi S, Castellsague X, Wei Q, Sturgis EM, Morgenstern H, Zhang ZF, Levi F, Talamini R, Smith E, ... ... Lazarus P, et al. Type of alcoholic beverage and risk of head and neck cancer--a pooled analysis within the INHANCE Consortium. American Journal of Epidemiology. 169: 132-42. PMID 19064644 DOI: 10.1093/Aje/Kwn306 |
0.322 |
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| 2009 |
Gallagher CJ, Ahn K, Knipe AL, Dyer AM, Richie JP, Lazarus P, Muscat JE. Association between haplotypes of manganese superoxide dismutase (SOD2), smoking, and lung cancer risk. Free Radical Biology & Medicine. 46: 20-4. PMID 18930810 DOI: 10.1016/J.Freeradbiomed.2008.09.018 |
0.389 |
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| 2009 |
Negri E, Boffetta P, Berthiller J, Castellsague X, Curado MP, Dal Maso L, Daudt AW, Fabianova E, Fernandez L, Wünsch-Filho V, Franceschi S, Hayes RB, Herrero R, Koifman S, Lazarus P, et al. Family history of cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. International Journal of Cancer. Journal International Du Cancer. 124: 394-401. PMID 18814262 DOI: 10.1002/Ijc.23848 |
0.349 |
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| 2008 |
Hung RJ, Christiani DC, Risch A, Popanda O, Haugen A, Zienolddiny S, Benhamou S, Bouchardy C, Lan Q, Spitz MR, Wichmann HE, LeMarchand L, Vineis P, Matullo G, Kiyohara C, ... ... Lazarus P, et al. International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 3081-9. PMID 18990748 DOI: 10.1158/1055-9965.Epi-08-0411 |
0.38 |
|
| 2008 |
Lee YC, Boffetta P, Sturgis EM, Wei Q, Zhang ZF, Muscat J, Lazarus P, Matos E, Hayes RB, Winn DM, Zaridze D, Wünsch-Filho V, Eluf-Neto J, Koifman S, Mates D, et al. Involuntary smoking and head and neck cancer risk: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 1974-81. PMID 18708387 DOI: 10.1158/1055-9965.Epi-08-0047 |
0.353 |
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| 2008 |
Muscat JE, Pittman B, Kleinman W, Lazarus P, Stellman SD, Richie JP. Comparison of CYP1A2 and NAT2 phenotypes between black and white smokers. Biochemical Pharmacology. 76: 929-37. PMID 18703023 DOI: 10.1016/J.Bcp.2008.07.024 |
0.406 |
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| 2008 |
Nichenametla SN, Ellison I, Calcagnotto A, Lazarus P, Muscat JE, Richie JP. Functional significance of the GAG trinucleotide-repeat polymorphism in the gene for the catalytic subunit of gamma-glutamylcysteine ligase. Free Radical Biology & Medicine. 45: 645-50. PMID 18549827 DOI: 10.1016/J.Freeradbiomed.2008.05.012 |
0.355 |
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| 2008 |
Chen G, Dellinger RW, Gallagher CJ, Sun D, Lazarus P. Identification of a prevalent functional missense polymorphism in the UGT2B10 gene and its association with UGT2B10 inactivation against tobacco-specific nitrosamines. Pharmacogenetics and Genomics. 18: 181-91. PMID 18300939 DOI: 10.1097/Fpc.0B013E3282F4Dbdd |
0.378 |
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| 2008 |
Chen G, Dellinger RW, Sun D, Spratt TE, Lazarus P. Glucuronidation of tobacco-specific nitrosamines by UGT2B10. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 824-30. PMID 18238858 DOI: 10.1124/Dmd.107.019406 |
0.349 |
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| 2008 |
Gallagher CJ, Kadlubar FF, Muscat JE, Ambrosone CB, Lang NP, Lazarus P. The UGT2B17 gene deletion polymorphism and risk of prostate cancer: A case-control study in Caucasians Cancer Detection and Prevention. 32: 186-187. DOI: 10.1016/J.Cdp.2008.08.005 |
0.326 |
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| 2007 |
Gallagher CJ, Kadlubar FF, Muscat JE, Ambrosone CB, Lang NP, Lazarus P. The UGT2B17 gene deletion polymorphism and risk of prostate cancer. A case-control study in Caucasians. Cancer Detection and Prevention. 31: 310-5. PMID 17935910 DOI: 10.1016/J.Cdp.2007.07.005 |
0.407 |
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| 2007 |
Chen G, Blevins-Primeau AS, Dellinger RW, Muscat JE, Lazarus P. Glucuronidation of nicotine and cotinine by UGT2B10: loss of function by the UGT2B10 Codon 67 (Asp>Tyr) polymorphism. Cancer Research. 67: 9024-9. PMID 17909004 DOI: 10.1158/0008-5472.Can-07-2245 |
0.352 |
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| 2007 |
Sun D, Sharma AK, Dellinger RW, Blevins-Primeau AS, Balliet RM, Chen G, Boyiri T, Amin S, Lazarus P. Glucuronidation of active tamoxifen metabolites by the human UDP glucuronosyltransferases. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 2006-14. PMID 17664247 DOI: 10.1124/Dmd.107.017145 |
0.766 |
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| 2007 |
Dellinger RW, Chen G, Blevins-Primeau AS, Krzeminski J, Amin S, Lazarus P. Glucuronidation of PhIP and N-OH-PhIP by UDP-glucuronosyltransferase 1A10. Carcinogenesis. 28: 2412-8. PMID 17638922 DOI: 10.1093/Carcin/Bgm164 |
0.376 |
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| 2007 |
Zheng Y, Sun D, Sharma AK, Chen G, Amin S, Lazarus P. Elimination of antiestrogenic effects of active tamoxifen metabolites by glucuronidation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 1942-8. PMID 17620345 DOI: 10.1124/Dmd.107.016279 |
0.375 |
|
| 2007 |
Hashibe M, Brennan P, Benhamou S, Castellsague X, Chen C, Curado MP, Dal Maso L, Daudt AW, Fabianova E, Fernandez L, Wünsch-Filho V, Franceschi S, Hayes RB, Herrero R, Koifman S, ... ... Lazarus P, et al. Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. Journal of the National Cancer Institute. 99: 777-89. PMID 17505073 DOI: 10.1093/Jnci/Djk179 |
0.353 |
|
| 2007 |
Gallagher CJ, Muscat JE, Hicks AN, Zheng Y, Dyer AM, Chase GA, Richie J, Lazarus P. The UDP-glucuronosyltransferase 2B17 gene deletion polymorphism: sex-specific association with urinary 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol glucuronidation phenotype and risk for lung cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 823-8. PMID 17416778 DOI: 10.1158/1055-9965.Epi-06-0823 |
0.386 |
|
| 2006 |
Sun D, Chen G, Dellinger RW, Duncan K, Fang JL, Lazarus P. Characterization of tamoxifen and 4-hydroxytamoxifen glucuronidation by human UGT1A4 variants. Breast Cancer Research : Bcr. 8: R50. PMID 16884532 DOI: 10.1186/Bcr1539 |
0.415 |
|
| 2006 |
Dellinger RW, Fang JL, Chen G, Weinberg R, Lazarus P. Importance of UDP-glucuronosyltransferase 1A10 (UGT1A10) in the detoxification of polycyclic aromatic hydrocarbons: decreased glucuronidative activity of the UGT1A10139Lys isoform. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 943-9. PMID 16510539 DOI: 10.1124/Dmd.105.009100 |
0.461 |
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| 2005 |
Lazarus P, Zheng Y, Runkle EA, Muscat JE, Wiener D. Genotype-phenotype correlation between the polymorphic UGT2B17 gene deletion and NNAL glucuronidation activities in human liver microsomes. Pharmacogenetics and Genomics. 15: 769-78. PMID 16220109 DOI: 10.1097/01.Fpc.0000175596.52443.Ef |
0.38 |
|
| 2005 |
Park JY, Chen L, Elahi A, Lazarus P, Tockman MS. Genetic analysis of microsomal epoxide hydrolase gene and its association with lung cancer risk. European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (Ecp). 14: 223-30. PMID 15901990 DOI: 10.1097/00008469-200506000-00005 |
0.423 |
|
| 2004 |
Raimondi SC, Benhamou S, Coutelle C, Garte S, Hayes R, Kiemeney LALM, Lazarus P, Marchand LL, Morita S, Povey A, Romkes M, Zijno A, Taioli E. Association of metabolic gene polymorphisms with alcohol consumption in controls Biomarkers. 9: 180-189. PMID 15370874 DOI: 10.1080/13547500410001728381 |
0.314 |
|
| 2004 |
Park J, Chen L, Shade K, Lazarus P, Seigne J, Patterson S, Helal M, Pow-Sang J. Asp85tyr polymorphism in the udp-glucuronosyltransferase (UGT) 2B15 gene and the risk of prostate cancer. The Journal of Urology. 171: 2484-8. PMID 15126881 DOI: 10.1097/01.Ju.0000117748.44313.43 |
0.348 |
|
| 2004 |
Park J, Chen L, Tockman MS, Elahi A, Lazarus P. The human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) DNA repair enzyme and its association with lung cancer risk. Pharmacogenetics. 14: 103-9. PMID 15077011 DOI: 10.1097/00008571-200402000-00004 |
0.343 |
|
| 2004 |
Smits KM, Benhamou S, Garte S, Weijenberg MP, Alamanos Y, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Boffetta P, Bouchardy C, Brockmoller J, Butkiewicz D, Cascorbi I, ... ... Lazarus P, et al. Association of metabolic gene polymorphisms with tobacco consumption in healthy controls. International Journal of Cancer. Journal International Du Cancer. 110: 266-70. PMID 15069692 DOI: 10.1002/Ijc.20114 |
0.399 |
|
| 2004 |
Wiener D, Fang JL, Dossett N, Lazarus P. Correlation between UDP-glucuronosyltransferase genotypes and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone glucuronidation phenotype in human liver microsomes. Cancer Research. 64: 1190-6. PMID 14871856 DOI: 10.1158/0008-5472.Can-03-3219 |
0.406 |
|
| 2004 |
Fang JL, Lazarus P. Correlation between the UDP-glucuronosyltransferase (UGT1A1) TATAA box polymorphism and carcinogen detoxification phenotype: significantly decreased glucuronidating activity against benzo(a)pyrene-7,8-dihydrodiol(-) in liver microsomes from subjects with the UGT1A1*28 variant. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 13: 102-9. PMID 14744740 DOI: 10.1158/1055-9965.Epi-03-0070 |
0.38 |
|
| 2004 |
Wiener D, Doerge DR, Fang JL, Upadhyaya P, Lazarus P. Characterization of N-glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in human liver: importance of UDP-glucuronosyltransferase 1A4. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 72-9. PMID 14709623 DOI: 10.1124/Dmd.32.1.72 |
0.361 |
|
| 2004 |
Chen L, Elahi A, Pow-Sang J, Lazarus P, Park J. Association between polymorphism of human oxoguanine glycosylase 1 and risk of prostate cancer. The Journal of Urology. 170: 2471-4. PMID 14634453 DOI: 10.1097/01.Ju.0000087498.23008.Bb |
0.307 |
|
| 2003 |
Elahi A, Bendaly J, Zheng Z, Muscat JE, Richie JP, Schantz SP, Lazarus P. Detection of UGT1A10 polymorphisms and their association with orolaryngeal carcinoma risk. Cancer. 98: 872-80. PMID 12910533 DOI: 10.1002/Cncr.11587 |
0.414 |
|
| 2003 |
Park JY, Schantz SP, Lazarus P. Epoxide hydrolase genotype and orolaryngeal cancer risk: interaction with GSTM1 genotype. Oral Oncology. 39: 483-90. PMID 12747973 DOI: 10.1016/S1368-8375(03)00008-3 |
0.421 |
|
| 2003 |
Stellman SD, Chen Y, Muscat JE, Djordjevic MV, Richie JP, Lazarus P, Thompson S, Altorki N, Berwick M, Citron ML, Harlap S, Kaur TB, Neugut AI, Olson S, Travaline JM, et al. Lung cancer risk in white and black Americans. Annals of Epidemiology. 13: 294-302. PMID 12684197 DOI: 10.1016/S1047-2797(02)00420-9 |
0.328 |
|
| 2002 |
Elahi A, Zheng Z, Park J, Eyring K, McCaffrey T, Lazarus P. The human OGG1 DNA repair enzyme and its association with orolaryngeal cancer risk. Carcinogenesis. 23: 1229-34. PMID 12117782 DOI: 10.1093/Carcin/23.7.1229 |
0.411 |
|
| 2002 |
Zheng Z, Fang JL, Lazarus P. Glucuronidation: an important mechanism for detoxification of benzo[a]pyrene metabolites in aerodigestive tract tissues. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 30: 397-403. PMID 11901093 DOI: 10.1124/Dmd.30.4.397 |
0.358 |
|
| 2001 |
Zheng Z, Park JY, Guillemette C, Schantz SP, Lazarus P. Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk. Journal of the National Cancer Institute. 93: 1411-8. PMID 11562393 DOI: 10.1093/Jnci/93.18.1411 |
0.431 |
|
| 2001 |
Liu S, Park JY, Schantz SP, Stern JC, Lazarus P. Elucidation of CYP2E1 5′ regulatory RsaI/Pstl allelic variants and their role in risk for oral cancer Oral Oncology. 37: 437-445. PMID 11377232 DOI: 10.1016/S1368-8375(00)00099-3 |
0.362 |
|
| 2000 |
Lazarus P, Park JY. Metabolizing enzyme genotype and risk for upper aerodigestive tract cancer. Oral Oncology. 36: 421-31. PMID 10964048 DOI: 10.1016/S1368-8375(00)00030-0 |
0.452 |
|
| 2000 |
Kaur TB, Travaline JM, Gaughan JP, Richie JPJ, Stellman SD, Lazarus P. Role of Polymorphisms in Codons 143 and 160 of the O6-Alkylguanine DNA Alkyltransferase Gene in Lung Cancer Risk Cancer Epidemiology, Biomarkers & Prevention. 9: 339-342. DOI: 10.7916/D8416Vt0 |
0.394 |
|
| 1998 |
Muscat JE, Lazarus P. Risk of lung cancer from environmental exposures to tobacco smoke. Cancer Causes & Control : Ccc. 8: 929. PMID 9427436 DOI: 10.1023/A:1018428815632 |
0.339 |
|
| 1997 |
Muscat J, Citron M, Wang C, White A, Lazarus P. P53 protein overexpression in lung adenocarcinomas in non-smokers. Oncology Reports. 4: 825-7. PMID 21590150 DOI: 10.3892/Or.4.4.825 |
0.343 |
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