Shyam Biswal - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Environmental Health, Pathology, Molecular Biology

136 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Knany A, Engelman R, Hariri HA, Biswal S, Wolfenson H, Benhar M. S-nitrosocysteine and glutathione depletion synergize to induce cell death in human tumor cells: Insights into the redox and cytotoxic mechanisms. Free Radical Biology & Medicine. 160: 566-574. PMID 32898624 DOI: 10.1016/J.Freeradbiomed.2020.08.026  0.375
2020 Gangwar RS, Vinayachandran V, Rengasamy P, Chan R, Park B, Diamond-Zaluski R, Cara EA, Cha A, Das L, Asase C, Maiseyeu A, Deiuliis J, Zhong J, Mitzner W, Biswal S, et al. Differential contribution of bone marrow-derived infiltrating monocytes and resident macrophages to persistent lung inflammation in chronic air pollution exposure. Scientific Reports. 10: 14348. PMID 32873817 DOI: 10.1038/S41598-020-71144-1  0.402
2020 Ghosh B, Reyes-Caballero H, Akgün-Ölmez SG, Nishida K, Chandrala L, Smirnova L, Biswal S, Sidhaye VK. Effect of sub-chronic exposure to cigarette smoke, electronic cigarette and waterpipe on human lung epithelial barrier function. Bmc Pulmonary Medicine. 20: 216. PMID 32787821 DOI: 10.1186/S12890-020-01255-Y  0.372
2020 Rajagopalan S, Park B, Palanivel R, Vinayachandran V, Deiuliis JA, Gangwar RS, Das LM, Yin J, Choi Y, Al-Kindi S, Jain MK, Hansen KD, Biswal S. Metabolic effects of air pollution exposure and reversibility. The Journal of Clinical Investigation. PMID 32780721 DOI: 10.1172/Jci137315  0.317
2020 Ramanathan M, Tharakan A, Sidhaye VK, Lane AP, Biswal S, London NR. Disruption of Sinonasal Epithelial Nrf2 Enhances Susceptibility to Rhinosinusitis in a Mouse Model. The Laryngoscope. PMID 32628788 DOI: 10.1002/Lary.28884  0.445
2020 Ghosh B, Park B, Bhowmik D, Nishida K, Lauver M, Putcha N, Gao P, Ramanathan M, Hansel NN, Biswal S, Sidhaye VK. Strong correlation between air-liquid interface cultures and in vivo transcriptomics of nasal brush biopsy. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 32233789 DOI: 10.1152/Ajplung.00050.2020  0.333
2019 Reyes-Caballero H, Park B, Loube J, Sanchez I, Vinayachandran V, Choi Y, Woo J, Edwards J, Brinkman MC, Sussan T, Mitzner W, Biswal S. Immune modulation by chronic exposure to waterpipe smoke and immediate-early gene regulation in murine lungs. Tobacco Control. PMID 31852817 DOI: 10.1136/Tobaccocontrol-2019-054965  0.408
2019 Sidhaye VK, Holbrook JT, Burke A, Sudini KR, Sethi S, Criner GJ, Fahey JW, Berenson CS, Jacobs MR, Thimmulappa R, Wise RA, Biswal S. Compartmentalization of anti-oxidant and anti-inflammatory gene expression in current and former smokers with COPD. Respiratory Research. 20: 190. PMID 31429757 DOI: 10.1186/S12931-019-1164-1  0.523
2019 London NR, Tharakan A, Mendiola M, Chen M, Dobzanski A, Sussan TE, Zaykaner M, Han AH, Lane AP, Sidhaye V, Biswal S, Ramanathan M. Nrf2 activation via Keap1 deletion or Sulforaphane treatment reduces Ova-induced sinonasal inflammation. Allergy. PMID 30843229 DOI: 10.1111/All.13766  0.356
2019 Rao X, Asico LD, Zanos P, Mahabeleshwar GH, Singh Gangwar R, Xia C, Duan L, Cisse YM, Rengasamy P, Jose PA, Gould TD, Nelson R, Biswal S, Chen LC, Zhong J, et al. Alpha2B-Adrenergic Receptor Overexpression in the Brain Potentiate Air Pollution-induced Behavior and Blood Pressure Changes. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30812033 DOI: 10.1093/Toxsci/Kfz025  0.334
2018 London NR, Tharakan A, Mendiola M, Sussan TE, Chen M, Dobzanski A, Lane AP, Sidhaye V, Biswal S, Ramanathan M. Deletion of Nrf2 enhances susceptibility to eosinophilic sinonasal inflammation in a murine model of rhinosinusitis. International Forum of Allergy & Rhinology. PMID 30281933 DOI: 10.1002/Alr.22222  0.455
2018 Singh A, Ruiz C, Bhalla K, Haley JA, Li QK, Acquaah-Mensah G, Montal E, Sudini KR, Skoulidis F, Wistuba II, Papadimitrakopoulou V, Heymach JV, Boros LG, Gabrielson E, Carretero J, ... ... Biswal S, et al. De novo lipogenesis represents a therapeutic target in mutant Kras non-small cell lung cancer. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800204. PMID 29906244 DOI: 10.1096/Fj.201800204  0.341
2018 Walker A, Singh A, Tully E, Woo J, Le A, Nguyen T, Biswal S, Sharma D, Gabrielson E. Nrf2 signaling and autophagy are complementary in protecting breast cancer cells during glucose deprivation. Free Radical Biology & Medicine. PMID 29649567 DOI: 10.1016/J.Freeradbiomed.2018.04.009  0.306
2018 Moran M, Biswal S, Cohen J, Henderson R, Holbrook J, Sidhaye V, Wise R. Prevalence and correlates of ENDS use among adults being treated for chronic lung disease Tobacco Induced Diseases. 16. DOI: 10.18332/Tid/84019  0.337
2017 Gao L, Zimmerman MC, Biswal S, Zucker IH. Selective Nrf2 Gene Deletion in the Rostral Ventrolateral Medulla Evokes Hypertension and Sympathoexcitation in Mice. Hypertension (Dallas, Tex. : 1979). PMID 28461605 DOI: 10.1161/Hypertensionaha.117.09123  0.346
2017 Wu M, Gibbons JG, Deloid GM, Bedugnis AS, Thimmulappa RK, Biswal S, Kobzik L. Immunomodulators Targeting MARCO Expression Improve Resistance to Post-influenza Bacterial Pneumonia. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00075.2017. PMID 28408365 DOI: 10.1152/Ajplung.00075.2017  0.361
2017 Singh SP, Chand HS, Langley RJ, Mishra N, Barrett T, Rudolph K, Tellez C, Filipczak PT, Belinsky S, Saeed AI, Sheybani A, Exil V, Agarwal H, Sidhaye VK, Sussan T, ... Biswal S, et al. Gestational Exposure to Sidestream (Secondhand) Cigarette Smoke Promotes Transgenerational Epigenetic Transmission of Exacerbated Allergic Asthma and Bronchopulmonary Dysplasia. Journal of Immunology (Baltimore, Md. : 1950). PMID 28381639 DOI: 10.4049/Jimmunol.1700014  0.412
2017 Ramanathan M, London NR, Tharakan A, Surya N, Sussan TE, Rao X, Lin SY, Toskala E, Rajagopalan S, Biswal S. Airborne Particulate Matter Induces Non-allergic Eosinophilic Sinonasal Inflammation in Mice. American Journal of Respiratory Cell and Molecular Biology. PMID 28245149 DOI: 10.1165/Rcmb.2016-0351Oc  0.363
2017 London NR, Tharakan A, Lane AP, Biswal S, Ramanathan M. Nuclear erythroid 2-related factor 2 activation inhibits house dust mite-induced sinonasal epithelial cell barrier dysfunction. International Forum of Allergy & Rhinology. PMID 28151586 DOI: 10.1002/Alr.21916  0.377
2017 Sussan TE, Sudini K, Talbot CC, Wang X, Wills-Karp M, Burd I, Biswal S. Nrf2 regulates gene-environment interactions in an animal model of intrauterine inflammation: Implications for preterm birth and prematurity. Scientific Reports. 7: 40194. PMID 28071748 DOI: 10.1038/Srep40194  0.448
2016 Wise RA, Holbrook JT, Criner G, Sethi S, Rayapudi S, Sudini KR, Sugar EA, Burke A, Thimmulappa R, Singh A, Talalay P, Fahey JW, Berenson CS, Jacobs MR, Biswal S, et al. Lack of Effect of Oral Sulforaphane Administration on Nrf2 Expression in COPD: A Randomized, Double-Blind, Placebo Controlled Trial. Plos One. 11: e0163716. PMID 27832073 DOI: 10.1371/Journal.Pone.0163716  0.437
2016 Tharakan A, Halderman AA, Lane AP, Biswal S, Ramanathan M. Reversal of cigarette smoke extract-induced sinonasal epithelial cell barrier dysfunction through Nrf2 Activation. International Forum of Allergy & Rhinology. PMID 27580429 DOI: 10.1002/Alr.21827  0.412
2016 London NR, Tharakan A, Rule AM, Lane AP, Biswal S, Ramanathan M. Air pollutant-mediated disruption of sinonasal epithelial cell barrier function is reversed by activation of the Nrf2 pathway. The Journal of Allergy and Clinical Immunology. PMID 27576127 DOI: 10.1016/J.Jaci.2016.06.027  0.33
2016 Singh A, Venkannagari S, Oh KH, Zhang YQ, Liu L, Rohde JM, Nimmagadda S, Sudini K, Brimacombe KR, Gajghate S, Ma J, Wang A, Xu X, Shahane SA, Xia M, ... ... Biswal S, et al. Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumors. Acs Chemical Biology. PMID 27552339 DOI: 10.1021/Acschembio.6B00651  0.345
2016 Sudini K, Diette GB, Breysse PN, McCormack MC, Bull D, Biswal S, Zhai S, Brereton N, Peng RD, Matsui EC. A Randomized Controlled Trial of the Effect of Broccoli Sprouts on Antioxidant Gene Expression and Airway Inflammation in Asthmatics. The Journal of Allergy and Clinical Immunology. in Practice. PMID 27130714 DOI: 10.1016/J.Jaip.2016.03.012  0.387
2016 Pinkerton J, Kim R, Essilfie A, Rae B, Mayall J, Ali MK, Starkey M, Wood L, Biswal S, Horvat J, Hansbro P. Investigating antioxidant therapy for steroid-resistant asthma European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa570  0.393
2015 Lounsbury N, Mateo G, Jones B, Papaiahgari S, Thimmulappa RK, Teijaro C, Gordon J, Korzekwa K, Ye M, Allaway G, Abou-Gharbia M, Biswal S, Childers W. Heterocyclic chalcone activators of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) with improved in vivo efficacy. Bioorganic & Medicinal Chemistry. 23: 5352-9. PMID 26278028 DOI: 10.1016/J.Bmc.2015.07.056  0.343
2015 Sussan TE, Gajghate S, Chatterjee S, Mandke P, McCormick S, Sudini K, Kumar S, Breysse PN, Diette GB, Sidhaye VK, Biswal S. Nrf2 reduces allergic asthma in mice through enhanced airway epithelial cytoprotective function. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00398.2014. PMID 25957295 DOI: 10.1152/Ajplung.00398.2014  0.36
2015 Chen H, Jin S, Guo J, Kombairaju P, Biswal S, Zirkin BR. Knockout of the transcription factor Nrf2: Effects on testosterone production by aging mouse Leydig cells. Molecular and Cellular Endocrinology. 409: 113-20. PMID 25818884 DOI: 10.1016/J.Mce.2015.03.013  0.348
2015 Sussan TE, Gajghate S, Thimmulappa RK, Ma J, Kim JH, Sudini K, Consolini N, Cormier SA, Lomnicki S, Hasan F, Pekosz A, Biswal S. Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model. Plos One. 10: e0116861. PMID 25651083 DOI: 10.1371/Journal.Pone.0116861  0.37
2014 Malhotra D, Thimmulappa RK, Mercado N, Ito K, Kombairaju P, Kumar S, Ma J, Feller-Kopman D, Wise R, Barnes P, Biswal S. Retraction: Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients. The Journal of Clinical Investigation. 124: 5521. PMID 25438060 DOI: 10.1172/JCI79606  0.699
2014 Kombairaju P, Kerr JP, Roche JA, Pratt SJ, Lovering RM, Sussan TE, Kim JH, Shi G, Biswal S, Ward CW. Genetic silencing of Nrf2 enhances X-ROS in dysferlin-deficient muscle. Frontiers in Physiology. 5: 57. PMID 24600403 DOI: 10.3389/Fphys.2014.00057  0.376
2014 Kim JH, Thimmulappa RK, Kumar V, Cui W, Kumar S, Kombairaju P, Zhang H, Margolick J, Matsui W, Macvittie T, Malhotra SV, Biswal S. NRF2-mediated Notch pathway activation enhances hematopoietic reconstitution following myelosuppressive radiation. The Journal of Clinical Investigation. 124: 730-41. PMID 24463449 DOI: 10.1172/Jci70812  0.365
2014 Wakabayashi N, Skoko JJ, Chartoumpekis DV, Kimura S, Slocum SL, Noda K, Palliyaguru DL, Fujimuro M, Boley PA, Tanaka Y, Shigemura N, Biswal S, Yamamoto M, Kensler TW. Notch-Nrf2 axis: regulation of Nrf2 gene expression and cytoprotection by notch signaling. Molecular and Cellular Biology. 34: 653-63. PMID 24298019 DOI: 10.1128/Mcb.01408-13  0.375
2014 McGrath-Morrow SA, Lauer T, Collaco JM, Lopez A, Malhotra D, Alekseyev YO, Neptune E, Wise R, Biswal S. Transcriptional responses of neonatal mouse lung to hyperoxia by Nrf2 status. Cytokine. 65: 4-9. PMID 24139870 DOI: 10.1016/J.Cyto.2013.09.021  0.771
2014 Sussan TE, Ingole V, Kim JH, McCormick S, Negherbon J, Fallica J, Akulian J, Yarmus L, Feller-Kopman D, Wills-Karp M, Horton MR, Breysse PN, Agrawal A, Juvekar S, Salvi S, ... Biswal S, et al. Source of biomass cooking fuel determines pulmonary response to household air pollution. American Journal of Respiratory Cell and Molecular Biology. 50: 538-48. PMID 24102120 DOI: 10.1165/Rcmb.2013-0201Oc  0.354
2014 Ward CW, Kerr JP, Kombairaju P, Sussan TE, Pratt SJ, Lovering RM, Khairallah R, Biswal S. Targeting NRF2 Activation Modulates X-Ros Signaling in Dystrophic Skeletal Muscle Biophysical Journal. 106: 727a. DOI: 10.1016/J.Bpj.2013.11.4012  0.375
2013 Aggarwal NR, Chau E, Garibaldi BT, Mock JR, Sussan T, Rao K, Rao K, Menon AG, D'Alessio FR, Damarla M, Biswal S, King LS, Sidhaye VK. Aquaporin 5 regulates cigarette smoke induced emphysema by modulating barrier and immune properties of the epithelium. Tissue Barriers. 1: e25248. PMID 24665410 DOI: 10.4161/Tisb.25248  0.54
2013 Lam HC, Cloonan SM, Bhashyam AR, Haspel JA, Singh A, Sathirapongsasuti JF, Cervo M, Yao H, Chung AL, Mizumura K, An CH, Shan B, Franks JM, Haley KJ, Owen CA, ... ... Biswal SS, et al. Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction. The Journal of Clinical Investigation. 123: 5212-30. PMID 24200693 DOI: 10.1172/Jci69636  0.356
2013 Leonardo CC, Agrawal M, Singh N, Moore JR, Biswal S, Doré S. Oral administration of the flavanol (-)-epicatechin bolsters endogenous protection against focal ischemia through the Nrf2 cytoprotective pathway. The European Journal of Neuroscience. 38: 3659-68. PMID 24112193 DOI: 10.1111/Ejn.12362  0.38
2013 Gajula RP, Chettiar ST, Williams RD, Thiyagarajan S, Kato Y, Aziz K, Wang R, Gandhi N, Wild AT, Vesuna F, Ma J, Salih T, Cades J, Fertig E, Biswal S, et al. The twist box domain is required for Twist1-induced prostate cancer metastasis. Molecular Cancer Research : McR. 11: 1387-400. PMID 23982216 DOI: 10.1158/1541-7786.Mcr-13-0218-T  0.306
2013 Mabalirajan U, Rehman R, Ahmad T, Kumar S, Leishangthem GD, Singh S, Dinda AK, Biswal S, Agrawal A, Ghosh B. 12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma. Scientific Reports. 3: 1540. PMID 23528921 DOI: 10.1038/Srep01540  0.35
2013 Mabalirajan U, Rehman R, Ahmad T, Kumar S, Singh S, Leishangthem GD, Aich J, Kumar M, Khanna K, Singh VP, Dinda AK, Biswal S, Agrawal A, Ghosh B. Linoleic acid metabolite drives severe asthma by causing airway epithelial injury. Scientific Reports. 3: 1349. PMID 23443229 DOI: 10.1038/Srep01349  0.354
2013 Kumar S, Singh BK, Prasad AK, Parmar VS, Biswal S, Ghosh B. Ethyl 3',4',5'-trimethoxythionocinnamate modulates NF-κB and Nrf2 transcription factors. European Journal of Pharmacology. 700: 32-41. PMID 23261968 DOI: 10.1016/J.Ejphar.2012.12.004  0.397
2013 Kumar S, Mabalirajan U, Rehman R, Singh BK, Parmar VS, Prasad AK, Biswal S, Ghosh B. A novel cinnamate derivative attenuates asthma features and reduces bronchial epithelial injury in mouse model. International Immunopharmacology. 15: 150-9. PMID 23137769 DOI: 10.1016/J.Intimp.2012.10.024  0.403
2013 Gajula RP, Chettiar ST, Williams RD, Thiyagarajan S, Kato Y, Aziz K, Wang R, Gandhi N, Wild AT, Vesuna F, Ma J, Salih T, Cades J, Fertig E, Biswal S, et al. Abstract 1493: The Twist box is required for Twist1-induced prostate cancer metastasis. Cancer Research. 73: 1493-1493. DOI: 10.1158/1538-7445.Am2013-1493  0.325
2012 Thimmulappa RK, Gang X, Kim JH, Sussan TE, Witztum JL, Biswal S. Oxidized phospholipids impair pulmonary antibacterial defenses: evidence in mice exposed to cigarette smoke. Biochemical and Biophysical Research Communications. 426: 253-9. PMID 22935414 DOI: 10.1016/J.Bbrc.2012.08.076  0.467
2012 Kombairaju P, Ma J, Thimmulappa RK, Yan SG, Gabrielson E, Singh A, Biswal S. Prolonged sulforaphane treatment does not enhance tumorigenesis in oncogenic K-ras and xenograft mouse models of lung cancer. Journal of Carcinogenesis. 11: 8. PMID 22919281 DOI: 10.4103/1477-3163.98459  0.39
2012 Acquaah-Mensah GK, Malhotra D, Vulimiri M, McDermott JE, Biswal S. Suppressed expression of T-box transcription factors is involved in senescence in chronic obstructive pulmonary disease. Plos Computational Biology. 8: e1002597. PMID 22829758 DOI: 10.1371/Journal.Pcbi.1002597  0.768
2012 Sandford AJ, Malhotra D, Boezen HM, Siedlinski M, Postma DS, Wong V, Akhabir L, He JQ, Connett JE, Anthonisen NR, Paré PD, Biswal S. NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease. Physiological Genomics. 44: 754-63. PMID 22693272 DOI: 10.1152/Physiolgenomics.00027.2012  0.749
2012 Traore K, Zirkin B, Thimmulappa RK, Biswal S, Trush MA. Upregulation of TLR1, TLR2, TLR4, and IRAK-2 Expression During ML-1 Cell Differentiation to Macrophages: Role in the Potentiation of Cellular Responses to LPS and LTA. Isrn Oncology. 2012: 641246. PMID 22685674 DOI: 10.5402/2012/641246  0.335
2012 Biswal S, Thimmulappa RK, Harvey CJ. Experimental therapeutics of Nrf2 as a target for prevention of bacterial exacerbations in COPD. Proceedings of the American Thoracic Society. 9: 47-51. PMID 22550241 DOI: 10.1513/pats.201201-009MS  0.374
2012 Reddy NM, Vegiraju S, Irving A, Paun BC, Luzina IG, Atamas SP, Biswal S, Ana NA, Mitzner W, Reddy SP. Targeted deletion of Jun/AP-1 in alveolar epithelial cells causes progressive emphysema and worsens cigarette smoke-induced lung inflammation. The American Journal of Pathology. 180: 562-74. PMID 22265050 DOI: 10.1016/J.Ajpath.2011.10.029  0.482
2012 Kumar S, Reddy L CS, Kumar Y, Kumar A, Singh BK, Kumar V, Malhotra S, Pandey MK, Jain R, Thimmulappa R, Sharma SK, Prasad AK, Biswal S, Van der Eycken E, DePass AL, et al. Arylalkyl ketones, benzophenones, desoxybenzoins and chalcones inhibit TNF-α induced expression of ICAM-1: structure-activity analysis. Archiv Der Pharmazie. 345: 368-77. PMID 22190402 DOI: 10.1002/Ardp.201100279  0.322
2011 Merchant AA, Singh A, Matsui W, Biswal S. The redox-sensitive transcription factor Nrf2 regulates murine hematopoietic stem cell survival independently of ROS levels. Blood. 118: 6572-9. PMID 22039262 DOI: 10.1182/Blood-2011-05-355362  0.408
2011 Malhotra D, Thimmulappa RK, Mercado N, Ito K, Kombairaju P, Kumar S, Ma J, Feller-Kopman D, Wise R, Barnes P, Biswal S. Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients. The Journal of Clinical Investigation. 121: 4289-302. PMID 22005302 DOI: 10.1172/Jci45144  0.759
2011 Wang B, Cao W, Biswal S, Doré S. Carbon monoxide-activated Nrf2 pathway leads to protection against permanent focal cerebral ischemia. Stroke; a Journal of Cerebral Circulation. 42: 2605-10. PMID 21852618 DOI: 10.1161/Strokeaha.110.607101  0.345
2011 Kong X, Thimmulappa R, Craciun F, Harvey C, Singh A, Kombairaju P, Reddy SP, Remick D, Biswal S. Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis. American Journal of Respiratory and Critical Care Medicine. 184: 928-38. PMID 21799073 DOI: 10.1164/Rccm.201102-0271Oc  0.371
2011 Zhou W, Dowell DR, Geraci MW, Blackwell TS, Collins RD, Polosukhin VV, Lawson WE, Wu P, Sussan T, Biswal S, Goleniewska K, O'Neal J, Newcomb DC, Toki S, Morrow JD, et al. PGI synthase overexpression protects against bleomycin-induced mortality and is associated with increased Nqo 1 expression. American Journal of Physiology. Lung Cellular and Molecular Physiology. 301: L615-22. PMID 21764988 DOI: 10.1152/Ajplung.00224.2010  0.413
2011 Alder JK, Guo N, Kembou F, Parry EM, Anderson CJ, Gorgy AI, Walsh MF, Sussan T, Biswal S, Mitzner W, Tuder RM, Armanios M. Telomere length is a determinant of emphysema susceptibility. American Journal of Respiratory and Critical Care Medicine. 184: 904-12. PMID 21757622 DOI: 10.1164/Rccm.201103-0520Oc  0.432
2011 Gao M, Singh A, Macri K, Reynolds C, Singhal V, Biswal S, Spannhake EW. Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system. Respiratory Research. 12: 92. PMID 21752292 DOI: 10.1186/1465-9921-12-92  0.373
2011 Reddy NM, Potteti HR, Mariani TJ, Biswal S, Reddy SP. Conditional deletion of Nrf2 in airway epithelium exacerbates acute lung injury and impairs the resolution of inflammation. American Journal of Respiratory Cell and Molecular Biology. 45: 1161-8. PMID 21659655 DOI: 10.1165/Rcmb.2011-0144Oc  0.472
2011 McGrath-Morrow S, Malhotra D, Lauer T, Collaco JM, Mitzner W, Neptune E, Wise R, Biswal S. Exposure to neonatal cigarette smoke causes durable lung changes but does not potentiate cigarette smoke-induced chronic obstructive pulmonary disease in adult mice. Experimental Lung Research. 37: 354-63. PMID 21649527 DOI: 10.3109/01902148.2011.577268  0.762
2011 Kumar V, Kumar S, Hassan M, Wu H, Thimmulappa RK, Kumar A, Sharma SK, Parmar VS, Biswal S, Malhotra SV. Novel chalcone derivatives as potent Nrf2 activators in mice and human lung epithelial cells. Journal of Medicinal Chemistry. 54: 4147-59. PMID 21539383 DOI: 10.1021/Jm2002348  0.446
2011 Harvey CJ, Thimmulappa RK, Sethi S, Kong X, Yarmus L, Brown RH, Feller-Kopman D, Wise R, Biswal S. Targeting Nrf2 signaling improves bacterial clearance by alveolar macrophages in patients with COPD and in a mouse model. Science Translational Medicine. 3: 78ra32. PMID 21490276 DOI: 10.1126/Scitranslmed.3002042  0.472
2011 Pandey MK, Kumar S, Thimmulappa RK, Parmar VS, Biswal S, Watterson AC. Design, synthesis and evaluation of novel PEGylated curcumin analogs as potent Nrf2 activators in human bronchial epithelial cells. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 43: 16-24. PMID 21426935 DOI: 10.1016/J.Ejps.2011.03.003  0.367
2011 Mercado N, Thimmulappa R, Thomas CM, Fenwick PS, Chana KK, Donnelly LE, Biswal S, Ito K, Barnes PJ. Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress. Biochemical and Biophysical Research Communications. 406: 292-8. PMID 21320471 DOI: 10.1016/J.Bbrc.2011.02.035  0.49
2011 Li QK, Singh A, Biswal S, Askin F, Gabrielson E. KEAP1 gene mutations and NRF2 activation are common in pulmonary papillary adenocarcinoma. Journal of Human Genetics. 56: 230-4. PMID 21248763 DOI: 10.1038/Jhg.2010.172  0.378
2011 McGrath-Morrow SA, Lauer T, Collaco JM, Yee M, O'Reilly M, Mitzner W, Neptune E, Wise R, Biswal S. Neonatal hyperoxia contributes additively to cigarette smoke-induced chronic obstructive pulmonary disease changes in adult mice. American Journal of Respiratory Cell and Molecular Biology. 45: 610-6. PMID 21239606 DOI: 10.1165/Rcmb.2010-0259Oc  0.43
2011 Malhotra S, Balwani S, Dhawan A, Singh BK, Kumar S, Thimmulappa R, Biswal S, Olsen CE, Eycken EVd, Prasad AK, Ghosh B, Parmar VS. Synthesis and biological activity evaluation of N-protected isatin derivatives as inhibitors of ICAM-1 expression on human endothelial cells Medchemcomm. 2: 743-751. DOI: 10.1039/C0Md00262C  0.306
2010 Singh A, Wu H, Zhang P, Happel C, Ma J, Biswal S. Expression of ABCG2 (BCRP) is regulated by Nrf2 in cancer cells that confers side population and chemoresistance phenotype. Molecular Cancer Therapeutics. 9: 2365-76. PMID 20682644 DOI: 10.1158/1535-7163.Mct-10-0108  0.394
2010 Wakabayashi N, Shin S, Slocum SL, Agoston ES, Wakabayashi J, Kwak MK, Misra V, Biswal S, Yamamoto M, Kensler TW. Regulation of notch1 signaling by nrf2: implications for tissue regeneration. Science Signaling. 3: ra52. PMID 20628156 DOI: 10.1126/Scisignal.2000762  0.39
2010 Solis LM, Behrens C, Dong W, Suraokar M, Ozburn NC, Moran CA, Corvalan AH, Biswal S, Swisher SG, Bekele BN, Minna JD, Stewart DJ, Wistuba II. Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 3743-53. PMID 20534738 DOI: 10.1158/1078-0432.Ccr-09-3352  0.391
2010 Kong X, Thimmulappa R, Kombairaju P, Biswal S. NADPH oxidase-dependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 185: 569-77. PMID 20511556 DOI: 10.4049/Jimmunol.0902315  0.408
2010 Yoshida T, Mett I, Bhunia AK, Bowman J, Perez M, Zhang L, Gandjeva A, Zhen L, Chukwueke U, Mao T, Richter A, Brown E, Ashush H, Notkin N, Gelfand A, ... ... Biswal S, et al. Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema. Nature Medicine. 16: 767-73. PMID 20473305 DOI: 10.1038/Nm.2157  0.482
2010 Malhotra D, Portales-Casamar E, Singh A, Srivastava S, Arenillas D, Happel C, Shyr C, Wakabayashi N, Kensler TW, Wasserman WW, Biswal S. Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis. Nucleic Acids Research. 38: 5718-34. PMID 20460467 DOI: 10.1093/Nar/Gkq212  0.769
2010 Singh A, Bodas M, Wakabayashi N, Bunz F, Biswal S. Gain of Nrf2 function in non-small-cell lung cancer cells confers radioresistance. Antioxidants & Redox Signaling. 13: 1627-37. PMID 20446773 DOI: 10.1089/Ars.2010.3219  0.448
2010 Shah ZA, Li RC, Ahmad AS, Kensler TW, Yamamoto M, Biswal S, Doré S. The flavanol (-)-epicatechin prevents stroke damage through the Nrf2/HO1 pathway. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 1951-61. PMID 20442725 DOI: 10.1038/Jcbfm.2010.53  0.332
2010 Zhang P, Singh A, Yegnasubramanian S, Esopi D, Kombairaju P, Bodas M, Wu H, Bova SG, Biswal S. Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth. Molecular Cancer Therapeutics. 9: 336-46. PMID 20124447 DOI: 10.1158/1535-7163.Mct-09-0589  0.375
2010 Rangasamy T, Williams MA, Bauer S, Trush MA, Emo J, Georas SN, Biswal S. Nuclear erythroid 2 p45-related factor 2 inhibits the maturation of murine dendritic cells by ragweed extract. American Journal of Respiratory Cell and Molecular Biology. 43: 276-85. PMID 19805484 DOI: 10.1165/Rcmb.2008-0438Oc  0.37
2010 Cano M, Thimmalappula R, Fujihara M, Nagai N, Sporn M, Wang AL, Neufeld AH, Biswal S, Handa JT. Cigarette smoking, oxidative stress, the anti-oxidant response through Nrf2 signaling, and Age-related Macular Degeneration. Vision Research. 50: 652-64. PMID 19703486 DOI: 10.1016/J.Visres.2009.08.018  0.374
2010 Blake DJ, Singh A, Kombairaju P, Malhotra D, Mariani TJ, Tuder RM, Gabrielson E, Biswal S. Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation. American Journal of Respiratory Cell and Molecular Biology. 42: 524-36. PMID 19520915 DOI: 10.1165/Rcmb.2009-0054Oc  0.795
2010 Gemani D, Tobin LA, Singh A, Baer MR, Biswal S, Rassool F. The Dark Side of NRF2: Upregulation of NRF2 as a Mechanism for Resistance to Imatinib In CML. Blood. 116: 3401-3401. DOI: 10.1182/Blood.V116.21.3401.3401  0.384
2009 Malhotra D, Thimmulappa R, Vij N, Navas-Acien A, Sussan T, Merali S, Zhang L, Kelsen SG, Myers A, Wise R, Tuder R, Biswal S. Expression of concern: Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity. American Journal of Respiratory and Critical Care Medicine. 180: 1196-207. PMID 19797762 DOI: 10.1164/Rccm.200903-0324Oc  0.76
2009 Le A, Zielinski R, He C, Crow MT, Biswal S, Tuder RM, Becker PM. Pulmonary epithelial neuropilin-1 deletion enhances development of cigarette smoke-induced emphysema. American Journal of Respiratory and Critical Care Medicine. 180: 396-406. PMID 19520907 DOI: 10.1164/Rccm.200809-1483Oc  0.381
2009 Nagai N, Thimmulappa RK, Cano M, Fujihara M, Izumi-Nagai K, Kong X, Sporn MB, Kensler TW, Biswal S, Handa JT. Nrf2 is a critical modulator of the innate immune response in a model of uveitis. Free Radical Biology & Medicine. 47: 300-6. PMID 19410644 DOI: 10.1016/J.Freeradbiomed.2009.04.033  0.401
2009 An SS, Kim J, Ahn K, Trepat X, Drake KJ, Kumar S, Ling G, Purington C, Rangasamy T, Kensler TW, Mitzner W, Fredberg JJ, Biswal S. Cell stiffness, contractile stress and the role of extracellular matrix. Biochemical and Biophysical Research Communications. 382: 697-703. PMID 19327344 DOI: 10.1016/J.Bbrc.2009.03.118  0.341
2009 Rangasamy T, Misra V, Zhen L, Tankersley CG, Tuder RM, Biswal S. Cigarette smoke-induced emphysema in A/J mice is associated with pulmonary oxidative stress, apoptosis of lung cells, and global alterations in gene expression. American Journal of Physiology. Lung Cellular and Molecular Physiology. 296: L888-900. PMID 19286929 DOI: 10.1152/Ajplung.90369.2008  0.506
2009 McGrath-Morrow S, Lauer T, Yee M, Neptune E, Podowski M, Thimmulappa RK, O'Reilly M, Biswal S. Nrf2 increases survival and attenuates alveolar growth inhibition in neonatal mice exposed to hyperoxia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 296: L565-73. PMID 19151108 DOI: 10.1152/Ajplung.90487.2008  0.456
2009 Sussan TE, Rangasamy T, Blake DJ, Malhotra D, El-Haddad H, Bedja D, Yates MS, Kombairaju P, Yamamoto M, Liby KT, Sporn MB, Gabrielson KL, Champion HC, Tuder RM, Kensler TW, ... Biswal S, et al. Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 250-5. PMID 19104057 DOI: 10.1073/Pnas.0804333106  0.797
2009 Bivalacqua TJ, Sussan TE, Gebska MA, Strong TD, Berkowitz DE, Biswal S, Burnett AL, Champion HC. Sildenafil inhibits superoxide formation and prevents endothelial dysfunction in a mouse model of secondhand smoke induced erectile dysfunction. The Journal of Urology. 181: 899-906. PMID 19095260 DOI: 10.1016/J.Juro.2008.10.062  0.394
2009 Harvey CJ, Thimmulappa RK, Singh A, Blake DJ, Ling G, Wakabayashi N, Fujii J, Myers A, Biswal S. Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress. Free Radical Biology & Medicine. 46: 443-53. PMID 19028565 DOI: 10.1016/J.Freeradbiomed.2008.10.040  0.529
2009 Singh A, Ling G, Suhasini AN, Zhang P, Yamamoto M, Navas-Acien A, Cosgrove G, Tuder RM, Kensler TW, Watson WH, Biswal S. Nrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs. Free Radical Biology & Medicine. 46: 376-86. PMID 19027064 DOI: 10.1016/J.Freeradbiomed.2008.10.026  0.546
2009 Merchant A, Singh A, Joseph G, Wang Q, Zhang P, Brennan S, Biswal S, Matsui W. Nrf2, a Critical Regulator of Oxidative Stress, Is Required for HSC Function and Cytokine Response. Blood. 114: 1492-1492. DOI: 10.1182/Blood.V114.22.1492.1492  0.407
2008 Sussan TE, Jun J, Thimmulappa R, Bedja D, Antero M, Gabrielson KL, Polotsky VY, Biswal S. Disruption of Nrf2, a key inducer of antioxidant defenses, attenuates ApoE-mediated atherosclerosis in mice. Plos One. 3: e3791. PMID 19023427 DOI: 10.1371/Journal.Pone.0003791  0.469
2008 Saleem S, Zhuang H, Biswal S, Christen Y, Doré S. Ginkgo biloba extract neuroprotective action is dependent on heme oxygenase 1 in ischemic reperfusion brain injury. Stroke; a Journal of Cerebral Circulation. 39: 3389-96. PMID 18845796 DOI: 10.1161/Strokeaha.108.523480  0.319
2008 Singh A, Boldin-Adamsky S, Thimmulappa RK, Rath SK, Ashush H, Coulter J, Blackford A, Goodman SN, Bunz F, Watson WH, Gabrielson E, Feinstein E, Biswal S. RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy. Cancer Research. 68: 7975-84. PMID 18829555 DOI: 10.1158/0008-5472.Can-08-1401  0.443
2008 Williams MA, Rangasamy T, Bauer SM, Killedar S, Karp M, Kensler TW, Yamamoto M, Breysse P, Biswal S, Georas SN. Disruption of the transcription factor Nrf2 promotes pro-oxidative dendritic cells that stimulate Th2-like immunoresponsiveness upon activation by ambient particulate matter. Journal of Immunology (Baltimore, Md. : 1950). 181: 4545-59. PMID 18802057 DOI: 10.4049/Jimmunol.181.7.4545  0.422
2008 Thimmulappa RK, Rangasamy T, Alam J, Biswal S. Dibenzoylmethane activates Nrf2-dependent detoxification pathway and inhibits benzo(a)pyrene induced DNA adducts in lungs. Medicinal Chemistry. 4: 473-481. PMID 18782044 DOI: 10.2174/157340608785700199  0.463
2008 Taylor RC, Acquaah-Mensah G, Singhal M, Malhotra D, Biswal S. Network inference algorithms elucidate Nrf2 regulation of mouse lung oxidative stress. Plos Computational Biology. 4: e1000166. PMID 18769717 DOI: 10.1371/Journal.Pcbi.1000166  0.754
2008 Fujihara M, Nagai N, Sussan TE, Biswal S, Handa JT. Chronic cigarette smoke causes oxidative damage and apoptosis to retinal pigmented epithelial cells in mice. Plos One. 3: e3119. PMID 18769672 DOI: 10.1371/Journal.Pone.0003119  0.358
2008 Malhotra D, Thimmulappa R, Navas-Acien A, Sandford A, Elliott M, Singh A, Chen L, Zhuang X, Hogg J, Pare P, Tuder RM, Biswal S. Expression of concern: Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1. American Journal of Respiratory and Critical Care Medicine. 178: 592-604. PMID 18556627 DOI: 10.1164/Rccm.200803-380Oc  0.789
2008 Moens AL, Takimoto E, Tocchetti CG, Chakir K, Bedja D, Cormaci G, Ketner EA, Majmudar M, Gabrielson K, Halushka MK, Mitchell JB, Biswal S, Channon KM, Wolin MS, Alp NJ, et al. Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy. Circulation. 117: 2626-36. PMID 18474817 DOI: 10.1161/Circulationaha.107.737031  0.373
2008 Huang K, Rabold R, Abston E, Schofield B, Misra V, Galdzicka E, Lee H, Biswal S, Mitzner W, Tankersley CG. Effects of leptin deficiency on postnatal lung development in mice. Journal of Applied Physiology (Bethesda, Md. : 1985). 105: 249-59. PMID 18467551 DOI: 10.1152/Japplphysiol.00052.2007  0.396
2008 Traore K, Sharma R, Thimmulappa RK, Watson WH, Biswal S, Trush MA. Redox-regulation of Erk1/2-directed phosphatase by reactive oxygen species: role in signaling TPA-induced growth arrest in ML-1 cells. Journal of Cellular Physiology. 216: 276-85. PMID 18270969 DOI: 10.1002/Jcp.21403  0.34
2008 McGrath-Morrow S, Rangasamy T, Cho C, Sussan T, Neptune E, Wise R, Tuder RM, Biswal S. Impaired lung homeostasis in neonatal mice exposed to cigarette smoke. American Journal of Respiratory Cell and Molecular Biology. 38: 393-400. PMID 17975176 DOI: 10.1165/Rcmb.2007-0104Oc  0.439
2008 Malhotra S, Shakya G, Kumar A, Vanhoecke BW, Cholli AL, Raj HG, Saso L, Ghosh B, Bracke ME, Prasad AK, Biswal S, Parmar VS. Antioxidant, antiinflammatory and antiinvasive activities of biopolyphenolics Arkivoc. 2008: 119-139. DOI: 10.3998/Ark.5550190.0009.612  0.336
2007 Papaiahgari S, Yerrapureddy A, Reddy SR, Reddy NM, Dodd-O JM, Crow MT, Grigoryev DN, Barnes K, Tuder RM, Yamamoto M, Kensler TW, Biswal S, Mitzner W, Hassoun PM, Reddy SP. Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice. American Journal of Respiratory and Critical Care Medicine. 176: 1222-35. PMID 17901416 DOI: 10.1164/Rccm.200701-060Oc  0.39
2007 Reddy NM, Kleeberger SR, Yamamoto M, Kensler TW, Scollick C, Biswal S, Reddy SP. Genetic dissection of the Nrf2-dependent redox signaling-regulated transcriptional programs of cell proliferation and cytoprotection. Physiological Genomics. 32: 74-81. PMID 17895394 DOI: 10.1152/Physiolgenomics.00126.2007  0.458
2007 Thimmulappa RK, Fuchs RJ, Malhotra D, Scollick C, Traore K, Bream JH, Trush MA, Liby KT, Sporn MB, Kensler TW, Biswal S. Preclinical evaluation of targeting the Nrf2 pathway by triterpenoids (CDDO-Im and CDDO-Me) for protection from LPS-induced inflammatory response and reactive oxygen species in human peripheral blood mononuclear cells and neutrophils. Antioxidants & Redox Signaling. 9: 1963-70. PMID 17822364 DOI: 10.1089/Ars.2007.1745  0.746
2007 Misra V, Lee H, Singh A, Huang K, Thimmulappa RK, Mitzner W, Biswal S, Tankersley CG. Global expression profiles from C57BL/6J and DBA/2J mouse lungs to determine aging-related genes. Physiological Genomics. 31: 429-40. PMID 17726092 DOI: 10.1152/Physiolgenomics.00060.2007  0.38
2007 Biswal S, Remick DG. Sepsis: redox mechanisms and therapeutic opportunities. Antioxidants & Redox Signaling. 9: 1959-61. PMID 17711390 DOI: 10.1089/Ars.2007.1808  0.459
2007 Shin S, Wakabayashi N, Misra V, Biswal S, Lee GH, Agoston ES, Yamamoto M, Kensler TW. NRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesis. Molecular and Cellular Biology. 27: 7188-97. PMID 17709388 DOI: 10.1128/Mcb.00915-07  0.385
2007 Wang J, Fields J, Zhao C, Langer J, Thimmulappa RK, Kensler TW, Yamamoto M, Biswal S, Doré S. Role of Nrf2 in protection against intracerebral hemorrhage injury in mice. Free Radical Biology & Medicine. 43: 408-14. PMID 17602956 DOI: 10.1016/J.Freeradbiomed.2007.04.020  0.363
2007 Shah ZA, Li RC, Thimmulappa RK, Kensler TW, Yamamoto M, Biswal S, Doré S. Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury. Neuroscience. 147: 53-9. PMID 17507167 DOI: 10.1016/J.Neuroscience.2007.02.066  0.364
2007 Reddy NM, Kleeberger SR, Cho HY, Yamamoto M, Kensler TW, Biswal S, Reddy SP. Deficiency in Nrf2-GSH signaling impairs type II cell growth and enhances sensitivity to oxidants. American Journal of Respiratory Cell and Molecular Biology. 37: 3-8. PMID 17413030 DOI: 10.1165/Rcmb.2007-0004Rc  0.459
2007 Huang K, Mitzner W, Rabold R, Schofield B, Lee H, Biswal S, Tankersley CG. Variation in senescent-dependent lung changes in inbred mouse strains. Journal of Applied Physiology (Bethesda, Md. : 1985). 102: 1632-9. PMID 17218422 DOI: 10.1152/Japplphysiol.00833.2006  0.361
2007 Balbir A, Lee H, Okumura M, Biswal S, Fitzgerald RS, Shirahata M. A search for genes that may confer divergent morphology and function in the carotid body between two strains of mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L704-15. PMID 17098806 DOI: 10.1152/Ajplung.00383.2006  0.339
2007 Kensler TW, Wakabayashi N, Biswal S. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annual Review of Pharmacology and Toxicology. 47: 89-116. PMID 16968214 DOI: 10.1146/Annurev.Pharmtox.46.120604.141046  0.475
2006 Thimmulappa RK, Scollick C, Traore K, Yates M, Trush MA, Liby KT, Sporn MB, Yamamoto M, Kensler TW, Biswal S. Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide. Biochemical and Biophysical Research Communications. 351: 883-9. PMID 17097057 DOI: 10.1016/J.Bbrc.2006.10.102  0.404
2006 Tuder RM, Yoshida T, Fijalkowka I, Biswal S, Petrache I. Role of lung maintenance program in the heterogeneity of lung destruction in emphysema. Proceedings of the American Thoracic Society. 3: 673-9. PMID 17065372 DOI: 10.1513/pats.200605-124SF  0.345
2006 Singh A, Misra V, Thimmulappa RK, Lee H, Ames S, Hoque MO, Herman JG, Baylin SB, Sidransky D, Gabrielson E, Brock MV, Biswal S. Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer. Plos Medicine. 3: e420. PMID 17020408 DOI: 10.1371/Journal.Pmed.0030420  0.445
2006 Osburn WO, Wakabayashi N, Misra V, Nilles T, Biswal S, Trush MA, Kensler TW. Nrf2 regulates an adaptive response protecting against oxidative damage following diquat-mediated formation of superoxide anion. Archives of Biochemistry and Biophysics. 454: 7-15. PMID 16962985 DOI: 10.1016/J.Abb.2006.08.005  0.417
2006 Singh A, Rangasamy T, Thimmulappa RK, Lee H, Osburn WO, Brigelius-Flohé R, Kensler TW, Yamamoto M, Biswal S. Glutathione peroxidase 2, the major cigarette smoke-inducible isoform of GPX in lungs, is regulated by Nrf2. American Journal of Respiratory Cell and Molecular Biology. 35: 639-50. PMID 16794261 DOI: 10.1165/Rcmb.2005-0325Oc  0.524
2006 Thimmulappa RK, Lee H, Rangasamy T, Reddy SP, Yamamoto M, Kensler TW, Biswal S. Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis. The Journal of Clinical Investigation. 116: 984-95. PMID 16585964 DOI: 10.1172/Jci25790  0.436
2006 Manna SK, Rangasamy T, Wise K, Sarkar S, Shishodia S, Biswal S, Ramesh GT. Long term environmental tobacco smoke activates nuclear transcription factor-kappa B, activator protein-1, and stress responsive kinases in mouse brain. Biochemical Pharmacology. 71: 1602-9. PMID 16569398 DOI: 10.1016/J.Bcp.2006.02.014  0.409
2005 Tian J, Ishibashi K, Ishibashi K, Reiser K, Grebe R, Biswal S, Gehlbach P, Handa JT. Advanced glycation endproduct-induced aging of the retinal pigment epithelium and choroid: A comprehensive transcriptional response Proceedings of the National Academy of Sciences of the United States of America. 102: 11846-11851. PMID 16081535 DOI: 10.1073/Pnas.0504759102  0.318
2005 Rangasamy T, Guo J, Mitzner WA, Roman J, Singh A, Fryer AD, Yamamoto M, Kensler TW, Tuder RM, Georas SN, Biswal S. Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice. The Journal of Experimental Medicine. 202: 47-59. PMID 15998787 DOI: 10.1084/Jem.20050538  0.461
2005 Chen H, Rubin E, Zhang H, Chung S, Jie CC, Garrett E, Biswal S, Sukumar S. Identification of transcriptional targets of HOXA5. The Journal of Biological Chemistry. 280: 19373-80. PMID 15757903 DOI: 10.1074/Jbc.M413528200  0.367
2004 Rangasamy T, Cho CY, Thimmulappa RK, Zhen L, Srisuma SS, Kensler TW, Yamamoto M, Petrache I, Tuder RM, Biswal S. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. The Journal of Clinical Investigation. 114: 1248-59. PMID 15520857 DOI: 10.1172/Jci21146  0.551
2003 Biswal S, Maxwell T, Rangasamy T, Kehrer JP. Modulation of benzo[a]pyrene-induced p53 DNA activity by acrolein. Carcinogenesis. 24: 1401-6. PMID 12807757 DOI: 10.1093/Carcin/Bgg061  0.32
2003 Srisuma S, Biswal SS, Mitzner WA, Gallagher SJ, Mai KH, Wagner EM. Identification of genes promoting angiogenesis in mouse lung by transcriptional profiling. American Journal of Respiratory Cell and Molecular Biology. 29: 172-9. PMID 12600816 DOI: 10.1165/Rcmb.2002-0276Oc  0.322
2002 Thimmulappa RK, Mai KH, Srisuma S, Kensler TW, Yamamoto M, Biswal S. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Cancer Research. 62: 5196-203. PMID 12234984  0.3
2002 Tirumalai R, Kumar TR, Mai KH, Biswal S. Acrolein causes transcriptional induction of phase II genes by activation of Nrf2 in human lung type II epithelial (A549) cells. Toxicology Letters. 132: 27-36. PMID 12084617 DOI: 10.1016/S0378-4274(02)00055-3  0.451
2002 Biswal S, Acquaah-Mensah G, Datta K, Wu X, Kehrer JP. Inhibition of cell proliferation and AP-1 activity by acrolein in human A549 lung adenocarcinoma cells due to thiol imbalance and covalent modifications. Chemical Research in Toxicology. 15: 180-6. PMID 11849044 DOI: 10.1021/Tx015552P  0.343
2001 Kehrer JP, Biswal SS, La E, Thuillier P, Datta K, Fischer SM, Vanden Heuvel JP. Inhibition of peroxisome-proliferator-activated receptor (PPAR)α by MK886 Biochemical Journal. 356: 899-906. PMID 11389700 DOI: 10.1042/0264-6021:3560899  0.345
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