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Jingyan Ge - Publications

Affiliations: 
2007-2012 Chemistry National University of Singapore, Singapore, Singapore 
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51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Shao J, Lin X, Wang H, Zhao C, Yao SQ, Ge J, Zeng S, Qian L. Targeted Degradation of Cell-Surface Proteins via Chaperone-Mediated Autophagy by Using Peptide-Conjugated Antibodies. Angewandte Chemie (International Ed. in English). e202319232. PMID 38472118 DOI: 10.1002/anie.202319232  0.613
2023 Zhang B, Brahma RK, Zhu L, Feng J, Hu S, Qian L, Du S, Yao SQ, Ge J. Insulin-like Growth Factor 2 (IGF2)-Fused Lysosomal Targeting Chimeras for Degradation of Extracellular and Membrane Proteins. Journal of the American Chemical Society. 145: 24272-24283. PMID 37899626 DOI: 10.1021/jacs.3c08886  0.784
2023 Zhu L, Zhou Y, Zhang B, Luo Y, Fang C, Yan X, Cai Y, Jiang L, Ge J. Conjugation with glucagon like peptide-1 enables targeted protein degradation. Bioorganic Chemistry. 141: 106908. PMID 37827016 DOI: 10.1016/j.bioorg.2023.106908  0.317
2023 Wang P, Liu J, Zhu X, Yan Z, Yan J, Jiang J, Fu M, Ge J, Zhu Q, Zheng Y. Modular synthesis of clickable peptides via late-stage maleimidation on C(7)-H tryptophan. Nature Communications. 14: 3973. PMID 37407547 DOI: 10.1038/s41467-023-39703-y  0.349
2023 Qian L, Lin X, Gao X, Khan RU, Liao JY, Du S, Ge J, Zeng S, Yao SQ. The Dawn of a New Era: Targeting the "Undruggables" with Antibody-Based Therapeutics. Chemical Reviews. PMID 37186942 DOI: 10.1021/acs.chemrev.2c00915  0.762
2023 Zhou Z, Zhang D, Du F, An W, Ge J, Yu C, Yang N, Zhang C, Lim K, Li L. Design and Synthesis of A Mitochondrial-Targeted JNK Inhibitor and Its Protective Effect on Parkinson's Disease Phenotypes. Chembiochem : a European Journal of Chemical Biology. e202200748. PMID 36946263 DOI: 10.1002/cbic.202200748  0.632
2023 Du W, Du S, Dong X, Bai H, Jiang J, Hao S, Yang F, Xiao Q, Zhang B, Ge J, Gao L, Li L, Yao SQ, Huang W. Biodegradable silica nanocapsules enable efficient nuclear-targeted delivery of native proteins for cancer therapy. Biomaterials. 294: 122000. PMID 36640541 DOI: 10.1016/j.biomaterials.2023.122000  0.807
2022 Ge J, Du S, Yao SQ. Bifunctional Lipid-Derived Affinity-Based Probes (ABPs) for Analysis of Lipid-Protein Interactome. Accounts of Chemical Research. 55: 3663-3674. PMID 36484537 DOI: 10.1021/acs.accounts.2c00593  0.731
2022 Wang S, Tan W, Lang W, Qian H, Guo S, Zhu L, Ge J. Fluorogenic and Mitochondria-Localizable Probe Enables Selective Labeling and Imaging of Nitroreductase. Analytical Chemistry. PMID 35549110 DOI: 10.1021/acs.analchem.2c00512  0.316
2022 Yu C, Wang S, Xu C, Ding Y, Zhang G, Yang N, Wu Q, Xiao Q, Wang L, Fang B, Pu C, Ge J, Gao L, Li L, Yao SQ. Two-Photon Small-Molecule Fluorogenic Probes for Visualizing Endogenous Nitroreductase Activities from Tumor Tissues of a Cancer Patient. Advanced Healthcare Materials. e2200400. PMID 35485404 DOI: 10.1002/adhm.202200400  0.76
2022 Lang W, Liew SS, Wang S, Hong D, Zhu L, Du S, Jiang L, Yao SQ, Ge J. Cell-penetrating poly(disulfide)-based nanoquenchers (CPDs) for self-monitoring of intracellular gene delivery. Chemical Communications (Cambridge, England). PMID 35040443 DOI: 10.1039/d1cc07020g  0.69
2021 Liu J, Wen Q, Zhou B, Yuan C, Du S, Li L, Jiang L, Yao SQ, Ge J. "Clickable" ZIF-8 for Cell-Type-Specific Delivery of Functional Proteins. Acs Chemical Biology. PMID 34936351 DOI: 10.1021/acschembio.1c00872  0.771
2020 Du S, Liew SS, Zhang CW, Du W, Lang W, Yao CCY, Li L, Ge J, Yao SQ. Cell-Permeant Bioadaptors for Cytosolic Delivery of Native Antibodies: A "Mix-and-Go" Approach. Acs Central Science. 6: 2362-2376. PMID 33376798 DOI: 10.1021/acscentsci.0c01379  0.75
2020 Lang W, Yuan C, Zhu L, Du S, Qian L, Ge J, Yao SQ. Recent advances in construction of small molecule-based fluorophore-drug conjugates. Journal of Pharmaceutical Analysis. 10: 434-443. PMID 33133727 DOI: 10.1016/J.Jpha.2020.08.006  0.773
2019 Li L, Liu J, Ding Y, Shi Z, Peng B, Yang N, Hong D, Zhang C, Yao C, Ge J, Huang W. Design, synthesis and evaluation of protein disulfide isomerase inhibitors with nitric oxide releasing activity. Bioorganic & Medicinal Chemistry Letters. 126898. PMID 31874828 DOI: 10.1016/J.Bmcl.2019.126898  0.512
2019 Ge J, Sun H, Li J, Shan Y, Zhao Y, Liao F, Yang Y, Cui X, Liu Z. Involvement of CHOP in activin A‑induced myeloma NS‑1 cell apoptosis. Oncology Reports. PMID 31638256 DOI: 10.3892/or.2019.7382  0.469
2019 Huang J, Hong D, Lang W, Liu J, Dong J, Yuan C, Luo J, Ge J, Zhu Q. Recent advances in reaction-based fluorescent probes for detecting monoamine oxidases in living systems. The Analyst. PMID 31062779 DOI: 10.1039/C9An00409B  0.415
2019 Lang W, Yuan C, Zhu B, Pan S, Liu J, Luo J, Nie S, Zhu Q, Lee JS, Ge J. Expanding the "minimalist" small molecule tagging approach to different bioactive compounds. Organic & Biomolecular Chemistry. PMID 30816385 DOI: 10.1039/C8Ob03175D  0.754
2019 Qian L, Pan S, Lee JS, Ge J, Li L, Yao SQ. Live-cell imaging and profiling of c-Jun N-terminal kinases using covalent inhibitor-derived probes. Chemical Communications (Cambridge, England). PMID 30620026 DOI: 10.1039/C8Cc09558B  0.757
2019 Dong J, Hong D, Lang W, Huang J, Qian L, Zhu Q, Li L, Ge J. Different tagged probes for protein profiling of mitochondria. Chembiochem : a European Journal of Chemical Biology. PMID 30600897 DOI: 10.1002/Cbic.201800735  0.662
2019 Ying S, Du S, Dong J, Ng BX, Zhang C, Li L, Ge J, Zhu Q. Intracellular effects of prodrug-like wortmannin probes Chinese Chemical Letters. 30: 67-70. DOI: 10.1016/J.Cclet.2018.05.030  0.768
2019 Dong J, Hong D, Lang W, Huang J, Qian L, Zhu Q, Li L, Ge J. Cover Feature: Differently Tagged Probes for Protein Profiling of Mitochondria (ChemBioChem 9/2019) Chembiochem. 20: 1089-1089. DOI: 10.1002/Cbic.201900221  0.637
2018 Han L, Shi R, Xin C, Ci Q, Ge J, Liu J, Wu Q, Zhang CW, Li L, Huang W. Mitochondrial Specific H2Sn Fluorogenic Probe for Live Cell Imaging by Rational Utilization of A Dual-Functional-Photocage Group. Acs Sensors. PMID 30145883 DOI: 10.1021/Acssensors.8B00456  0.315
2018 Xie Z, Yin B, Shen J, Hong D, Zhu L, Ge J, Zhu Q. A dual functional fluorogenic probe for visualization of intracellular pH and formaldehyde with distinct fluorescence signals. Organic & Biomolecular Chemistry. PMID 29901667 DOI: 10.1039/C8Ob00989A  0.391
2018 Zhang Y, Qi Y, Zhao Y, Sun H, Ge J, Liu Z. Activin A induces apoptosis of mouse myeloma cells via the mitochondrial pathway. Oncology Letters. 15: 2590-2594. PMID 29434978 DOI: 10.3892/ol.2017.7584  0.445
2017 Liew SS, Du S, Ge J, Pan S, Jang SY, Lee JS, Yao SQ. A chemoselective cleavable fluorescence turn-ON linker for proteomic studies. Chemical Communications (Cambridge, England). 53: 13332-13335. PMID 29188262 DOI: 10.1039/C7Cc08235E  0.792
2017 Fang H, Dou Y, Ge J, Chhabra M, Sun H, Zhang P, Zheng YG, Zhu Q. Regioselective and Direct Azidation of Anilines via Cu(II)-catalyzed C-H Functionalization in Water. The Journal of Organic Chemistry. PMID 28922913 DOI: 10.1021/Acs.Joc.7B01594  0.497
2017 Du S, Wang D, Lee JS, Peng B, Ge J, Yao SQ. Cell type-selective imaging and profiling of newly synthesized proteomes by using puromycin analogues. Chemical Communications (Cambridge, England). PMID 28702584 DOI: 10.1039/C7Cc04536K  0.797
2017 Wang D, Du S, Cazenave-Gassiot A, Ge J, Lee JS, Wenk MR, Yao SQ. Global Mapping of Protein-Lipid Interactions by Using Modified Choline-Containing Phospholipids Metabolically Synthesized in Live Cells. Angewandte Chemie (International Ed. in English). PMID 28429463 DOI: 10.1002/Anie.201702509  0.79
2017 Wei S, Ge J, He S, Zhang R, Zhao C, Fan Y, Yu S, Liu B, Zhu Q. A novel self-quenching system based on bis-naphthalimide: a dual two-photon-channel GSH fluorescent probe. Chemistry, An Asian Journal. PMID 28371228 DOI: 10.1002/Asia.201700340  0.394
2016 Xie Y, Ge J, Lei H, Peng B, Zhang H, Wang D, Pan S, Chen G, Chen L, Wang Y, Hao Q, Yao SQ, Sun H. Fluorescent Probes for Single-Step Detection and Proteomic Profiling of HDACs. Journal of the American Chemical Society. PMID 27805808 DOI: 10.1021/Jacs.6B07334  0.78
2016 Yu C, Qian L, Ge J, Fu J, Yuan P, Yao SC, Yao SQ. Cell-Penetrating Poly(disulfide)-Assisted Intracellular Delivery of Mesoporous Silica Nanoparticles for Inhibition of miR-21 Function and Detection of Subsequent Therapeutic Effects. Angewandte Chemie (International Ed. in English). PMID 27325284 DOI: 10.1002/Anie.201602188  0.762
2016 Zhu B, Zhang H, Pan S, Wang C, Ge J, Lee JS, Yao SQ. In Situ Proteome Profiling and Bioimaging Applications of Small-Molecule Affinity-Based Probes Derived From DOT1L Inhibitors. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27115831 DOI: 10.1002/Chem.201600259  0.796
2016 Ge J, Zhang CW, Ng XW, Peng B, Pan S, Du S, Wang D, Li L, Lim KL, Wohland T, Yao SQ. Puromycin Analogues Capable of Multiplexed Imaging and Profiling of Protein Synthesis and Dynamics in Live Cells and Neurons. Angewandte Chemie (International Ed. in English). PMID 26971527 DOI: 10.1002/Anie.201511030  0.785
2016 Xie Z, Ge J, Zhang H, Bai T, He S, Ling J, Sun H, Zhu Q. A highly selective two-photon fluorogenic probe for formaldehyde and its bioimaging application in cells and zebrafish Sensors and Actuators, B: Chemical. DOI: 10.1016/J.Snb.2016.10.039  0.52
2015 Shen W, Yu J, Ge J, Zhang R, Cheng F, Li X, Fan Y, Yu S, Liu B, Zhu Q. Light-up probes based on fluorogens with aggregation-induced emission characteristics for monoamine oxidase-A activity study in solution and in living cells. Acs Applied Materials & Interfaces. PMID 26666866 DOI: 10.1021/Acsami.5B10528  0.47
2015 Li L, Zhang CW, Ge J, Qian L, Chai BH, Zhu Q, Lee JS, Lim KL, Yao SQ. A Small-Molecule Probe for Selective Profiling and Imaging of Monoamine Oxidase B Activities in Models of Parkinson's Disease. Angewandte Chemie (International Ed. in English). PMID 26205378 DOI: 10.1002/Anie.201504441  0.774
2015 Ge J, Yao SQ. Chemical proteomics of host-pathogen interaction. Chemistry & Biology. 22: 434-5. PMID 25910239 DOI: 10.1016/J.Chembiol.2015.04.002  0.535
2015 Zhu B, Ge J, Yao SQ. Developing new chemical tools for DNA methyltransferase 1 (DNMT 1): A small-molecule activity-based probe and novel tetrazole-containing inhibitors. Bioorganic & Medicinal Chemistry. 23: 2917-27. PMID 25801160 DOI: 10.1016/J.Bmc.2015.03.006  0.682
2013 Zhang CJ, Tan CY, Ge J, Na Z, Chen GY, Uttamchandani M, Sun H, Yao SQ. Preparation of small-molecule microarrays by trans-cyclooctene tetrazine ligation and their application in the high-throughput screening of protein-protein interaction inhibitors of bromodomains. Angewandte Chemie (International Ed. in English). 52: 14060-4. PMID 24353229 DOI: 10.1002/Anie.201307803  0.788
2013 Ge J, Zhang CJ, Li L, Chong LM, Wu X, Hao P, Sze SK, Yao SQ. Small molecule probe suitable for in situ profiling and inhibition of protein disulfide isomerase. Acs Chemical Biology. 8: 2577-85. PMID 24070012 DOI: 10.1021/Cb4002602  0.757
2013 Su Y, Ge J, Zhu B, Zheng YG, Zhu Q, Yao SQ. Target identification of biologically active small molecules via in situ methods. Current Opinion in Chemical Biology. 17: 768-75. PMID 23796909 DOI: 10.1016/J.Cbpa.2013.06.005  0.744
2012 Li L, Ge J, Wu H, Xu QH, Yao SQ. Organelle-specific detection of phosphatase activities with two-photon fluorogenic probes in cells and tissues. Journal of the American Chemical Society. 134: 12157-67. PMID 22734946 DOI: 10.1021/Ja3036256  0.631
2012 Ge J, Cheng X, Tan LP, Yao SQ. Ugi reaction-assisted rapid assembly of affinity-based probes against potential protein tyrosine phosphatases. Chemical Communications (Cambridge, England). 48: 4453-5. PMID 22451009 DOI: 10.1039/C2Cc31294H  0.799
2011 Ge J, Li L, Yao SQ. A self-immobilizing and fluorogenic unnatural amino acid that mimics phosphotyrosine. Chemical Communications (Cambridge, England). 47: 10939-41. PMID 21909540 DOI: 10.1039/C1Cc14653J  0.527
2011 Wu H, Ge J, Uttamchandani M, Yao SQ. Small molecule microarrays: the first decade and beyond. Chemical Communications (Cambridge, England). 47: 5664-70. PMID 21494728 DOI: 10.1039/C1Cc11464F  0.728
2011 Wu H, Ge J, Yang PY, Wang J, Uttamchandani M, Yao SQ. A peptide aldehyde microarray for high-throughput profiling of cellular events. Journal of the American Chemical Society. 133: 1946-54. PMID 21247160 DOI: 10.1021/Ja109597V  0.789
2011 Wu H, Ge J, Uttamchandani M, Yao SQ. ChemInform Abstract: Small Molecule Microarrays: The First Decade and Beyond Cheminform. 42: no-no. DOI: 10.1002/chin.201133267  0.609
2010 Wu H, Ge J, Yao SQ. Microarray-assisted high-throughput identification of a cell-permeable small-molecule binder of 14-3-3 proteins. Angewandte Chemie (International Ed. in English). 49: 6528-32. PMID 20677307 DOI: 10.1002/Anie.201003257  0.624
2010 Kalesh KA, Shi H, Ge J, Yao SQ. The use of click chemistry in the emerging field of catalomics. Organic & Biomolecular Chemistry. 8: 1749-62. PMID 20449474 DOI: 10.1039/B923331H  0.608
2010 Ge J, Wu H, Yao SQ. An unnatural amino acid that mimics phosphotyrosine. Chemical Communications (Cambridge, England). 46: 2980-2. PMID 20386843 DOI: 10.1039/C000283F  0.573
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