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Zhengqiu Li - Publications

Affiliations: 
2010-2015 Chemistry National University of Singapore, Singapore, Singapore 
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36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zhao Y, Duan K, Fan Y, Li S, Huang L, Tu Z, Sun H, Cook GM, Yang J, Sun P, Tan Y, Ding K, Li Z. Catalyst-free late-stage functionalization to assemble α-acyloxyenamide electrophiles for selectively profiling conserved lysine residues. Communications Chemistry. 7: 31. PMID 38355988 DOI: 10.1038/s42004-024-01107-4  0.576
2024 Tang Z, Li J, Peng L, Xu F, Tan Y, He X, Zhu C, Zhang ZM, Zhang Z, Sun P, Ding K, Li Z. Novel Covalent Probe Selectively Targeting Glutathione Peroxidase 4 In Vivo: Potential Applications in Pancreatic Cancer Therapy. Journal of Medicinal Chemistry. PMID 38265413 DOI: 10.1021/acs.jmedchem.3c01608  0.367
2023 Lyu P, Li S, Han Y, Shen S, Feng Z, Hao P, Li Z, Lin L. Affinity-based protein profiling-driven discovery of myricanol as a Nampt activator. Bioorganic Chemistry. 133: 106435. PMID 36841049 DOI: 10.1016/j.bioorg.2023.106435  0.327
2023 Lv S, Xu F, Fan Y, Ding K, Li Z. Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. Journal of Medicinal Chemistry. 66: 2851-2864. PMID 36762554 DOI: 10.1021/acs.jmedchem.2c01889  0.419
2022 Liu Y, Liu J, Zhang X, Guo C, Xing X, Zhang ZM, Ding K, Li Z. Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. Acs Chemical Biology. PMID 36543757 DOI: 10.1021/acschembio.2c00740  0.36
2022 Xu J, Peng L, Guo C, Xu F, Lin DS, Tang Y, Li Z. Comparison of Different Competitive Proteome Profiling Approaches in Target Identification of Covalent Inhibitors. Chembiochem : a European Journal of Chemical Biology. PMID 36271784 DOI: 10.1002/cbic.202200389  0.421
2022 Li S, Zhang P, Xu F, Hu S, Liu J, Tan Y, Tu Z, Sun H, Zhang ZM, He QY, Sun P, Ding K, Li Z. Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. Journal of Medicinal Chemistry. PMID 35880853 DOI: 10.1021/acs.jmedchem.2c00272  0.573
2022 Lyu P, Jiang K, Zhou Y, Hu J, Chang Y, Zhang Z, Huang M, Zhang ZM, Ding K, Hao P, Lin L, Li Z. Proteome-wide Identification of Off-Targets of a Potent EGFR Mutant Inhibitor. Acs Medicinal Chemistry Letters. 13: 292-297. PMID 35178185 DOI: 10.1021/acsmedchemlett.1c00651  0.415
2021 Fan Y, Si H, Zhang Z, Zhong L, Sun H, Zhu C, Yin Z, Li H, Tang G, Yao SQ, Sun P, Zhang ZM, Ding K, Li Z. Novel Electrophilic Warhead Targeting a Triple-Negative Breast Cancer Driver in Live Cells Revealed by "Inverse Drug Discovery". Journal of Medicinal Chemistry. PMID 34623802 DOI: 10.1021/acs.jmedchem.0c02024  0.572
2021 Shen C, Zhang D, Xu F, Yang Y, Tan Y, Zhao Q, Li L, Ding K, Li Z. Two-photon fluorescent turn-on probes for highly efficient detection and profiling of thiols in live cells and tissues. Biological Chemistry. PMID 34505461 DOI: 10.1515/hsz-2021-0189  0.352
2021 Liu Y, Lv S, Peng L, Xie C, Gao L, Sun H, Lin L, Ding K, Li Z. Development and application of novel electrophilic warheads in target identification and drug discovery. Biochemical Pharmacology. 114636. PMID 34062128 DOI: 10.1016/j.bcp.2021.114636  0.714
2020 Xu J, Zhang Z, Lin L, Sun H, White LV, Ding K, Li Z. Quantitative Proteomics Reveals Cellular Off-Targets of a DDR1 Inhibitor. Acs Medicinal Chemistry Letters. 11: 535-540. PMID 32292561 DOI: 10.1021/Acsmedchemlett.9B00658  0.663
2020 Ma N, Hu J, Liu W, Huang M, Fan Y, Yin X, Wang J, Ding K, Ye W, Li Z, Zhang ZM. 2H-Azirine-based Reagents for Chemoselective Bioconjugation at Carboxyl Residues inside Live Cells. Journal of the American Chemical Society. PMID 32159959 DOI: 10.1021/Jacs.9B12116  0.43
2020 Lu K, Hou W, Xu XF, Chen Q, Li Z, Lin J, Chen WM. Biological evaluation and chemoproteomics reveal potential antibacterial targets of a cajaninstilbene-acid analogue. European Journal of Medicinal Chemistry. 188: 112026. PMID 31918072 DOI: 10.1016/J.Ejmech.2019.112026  0.404
2019 Li Z, Xu J, Li X. Applications of activity-based protein profiling (ABPP) and bioimaging in drug discovery. Chemistry, An Asian Journal. PMID 31762171 DOI: 10.1002/Asia.201901500  0.458
2019 Ma N, Zhang ZM, Lee JS, Cheng K, Lin L, Zhang DM, Hao P, Ding K, Ye WC, Li Z. Affinity-based Protein Profiling Reveals Cellular Targets of Photoreactive Anticancer Inhibitors. Acs Chemical Biology. PMID 31742988 DOI: 10.1021/Acschembio.9B00784  0.529
2019 Li Z, Zhu D, Guo H, Chang Y, Yin X, Ding K. Crenolanib-derived Probes Suitable for Cell- and Tissue-based Protein Profiling and Single Cell Imaging. Chembiochem : a European Journal of Chemical Biology. PMID 30942519 DOI: 10.1002/Cbic.201900067  0.532
2019 Wang X, Ma N, Wu R, Ding K, Li Z. A novel reactive turn-on probe capable of selective profiling and no-wash imaging of Bruton's tyrosine kinase in live cells. Chemical Communications (Cambridge, England). PMID 30829351 DOI: 10.1039/C9Cc01059A  0.509
2019 Liu W, Zhang Z, Zhang ZM, Hao P, Ding K, Li Z. Integrated phenotypic screening and activity-based protein profiling to reveal potential therapy targets of pancreatic cancer. Chemical Communications (Cambridge, England). PMID 30656306 DOI: 10.1039/C8Cc08753A  0.431
2018 Guo C, Chang Y, Wang X, Zhang C, Hao P, Ding K, Li Z. Minimalist linkers suitable for irreversible inhibitors in simultaneous proteome profiling, live-cell imaging and drug screening. Chemical Communications (Cambridge, England). PMID 30574960 DOI: 10.1039/C8Cc08685K  0.498
2018 Li Z, Zheng B, Guo H, Xu J, Ma N, Ni Y, Li L, Hao P, Ding K. Cell- and Tissue-based Proteome Profiling and Bioimaging with the Probes Derived from a Potent AXL Kinase Inhibitor. Chemistry, An Asian Journal. PMID 29939481 DOI: 10.1002/Asia.201800605  0.591
2018 Li Z, Zhu D, Guo H, Chang Y, Ni Y, Li L, Hao P, Xu Y, Ding K. Cell- and Tissue-based Proteome Profiling and Dual Imaging of Apoptosis Markers with Probes Derived from Venetoclax and Idasanutlin. Angewandte Chemie (International Ed. in English). PMID 29768700 DOI: 10.1002/Anie.201802003  0.568
2017 Guo H, Li Z. Developments of bioorthogonal handle-containing photo-crosslinkers for photoaffinity labeling. Medchemcomm. 8: 1585-1591. PMID 30108869 DOI: 10.1039/C7Md00217C  0.511
2017 Li Z, Cheng K, Lee JS, Yao SQ, Ding K. Tetrazole-Based Probes for Integrated Phenotypic Screening, Affinity-Based Proteome Profiling and Sensitive Detection of a Cancer Biomarker. Angewandte Chemie (International Ed. in English). PMID 28967196 DOI: 10.1002/Anie.201709584  0.428
2017 Guo H, Xu J, Hao P, Ding K, Li Z. Competitive affinity-based proteome profiling and imaging to reveal potential cellular targets of betulinic acid. Chemical Communications (Cambridge, England). PMID 28809973 DOI: 10.1039/C7Cc04190J  0.435
2017 Yao SQ, Pan S, Jang SY, Wang D, Liew SS, Li Z, Lee JS. A Suite of "Minimalist" Photo-Crosslinkers for Live-Cell Imaging and Chemical Proteomics: Case Study with BRD4 Inhibitors. Angewandte Chemie (International Ed. in English). PMID 28783236 DOI: 10.1002/Anie.201706076  0.736
2016 Chang Y, Zhang Q, Li Z, Ding K, Lu X. Leucine-Zipper and Sterile-α Motif Kinase (ZAK): A Potential target for Drug Discovery. Current Medicinal Chemistry. PMID 27655071  0.345
2016 Tan L, Zhang Z, Gao D, Luo J, Tu ZC, Li Z, Peng L, Ren X, Ding K. 4-Oxo-1, 4-Dihydroquinoline-3-Carboxamide Derivatives as New Axl Kinase Inhibitors. Journal of Medicinal Chemistry. PMID 27379978 DOI: 10.1021/Acs.Jmedchem.6B00608  0.435
2016 Li Z, Qian L, Li L, Bernhammer JC, Huynh HV, Lee JS, Yao SQ. Corrigendum: Tetrazole Photoclick Chemistry: Reinvestigating Its Suitability as a Bioorthogonal Reaction and Potential Applications. Angewandte Chemie (International Ed. in English). 55: 3254. PMID 26915355 DOI: 10.1002/anie.201600314  0.608
2015 Li Z, Qian L, Li L, Bernhammer JC, Huynh HV, Lee JS, Yao SQ. Tetrazole Photoclick Chemistry: Reinvestigating Its Suitability as a Bioorthogonal Reaction and Potential Applications. Angewandte Chemie (International Ed. in English). PMID 26640085 DOI: 10.1002/Anie.201508104  0.688
2015 Su Y, Pan S, Li Z, Li L, Wu X, Hao P, Sze SK, Yao SQ. Multiplex imaging and cellular target identification of kinase inhibitors via an affinity-based proteome profiling approach. Scientific Reports. 5: 7724. PMID 25579846 DOI: 10.1038/Srep07724  0.743
2014 Li Z, Wang D, Li L, Pan S, Na Z, Tan CY, Yao SQ. "Minimalist" cyclopropene-containing photo-cross-linkers suitable for live-cell imaging and affinity-based protein labeling. Journal of the American Chemical Society. 136: 9990-8. PMID 24972113 DOI: 10.1021/Ja502780Z  0.753
2013 Li Z, Hao P, Li L, Tan CY, Cheng X, Chen GY, Sze SK, Shen HM, Yao SQ. Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Angewandte Chemie (International Ed. in English). 52: 8551-6. PMID 23754342 DOI: 10.1002/Anie.201300683  0.705
2013 Tam EK, Li Z, Goh YL, Cheng X, Wong SY, Santhanakrishnan S, Chai CL, Yao SQ. Cell-based proteome profiling using an affinity-based probe (AfBP) derived from 3-deazaneplanocin A (DzNep). Chemistry, An Asian Journal. 8: 1818-28. PMID 23749335 DOI: 10.1002/Asia.201300303  0.749
2013 Zhou J, Ng S, Huang Q, Wu YT, Li Z, Yao SQ, Shen HM. AMPK mediates a pro-survival autophagy downstream of PARP-1 activation in response to DNA alkylating agents. Febs Letters. 587: 170-7. PMID 23201261 DOI: 10.1016/J.Febslet.2012.11.018  0.471
2012 Yao SQ, Li ZZ, Huang QY, Li F, Wang ZW, Augusto E, He JC, Wang XT, Chen JF, Zheng RY. Genetic inactivation of the adenosine A(2A) receptor exacerbates brain damage in mice with experimental autoimmune encephalomyelitis. Journal of Neurochemistry. 123: 100-12. PMID 22639925 DOI: 10.1111/J.1471-4159.2012.07807.X  0.339
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