| Year |
Citation |
Score |
| 2024 |
Yousof TR, Bouchard CC, Alb M, Lynn EG, Lhoták S, Jiang H, MacDonald M, Li H, Byun JH, Makda Y, Athanasopoulos M, Maclean KN, Cherrington N, Naqvi A, Igdoura S, et al. Restoration of the ER stress response protein TDAG51 in hepatocytes mitigates NAFLD in mice. The Journal of Biological Chemistry. 105655. PMID 38237682 DOI: 10.1016/j.jbc.2024.105655 |
0.422 |
|
| 2023 |
Frost KL, Jilek JL, Toth EL, Goedken MJ, Wright SH, Cherrington NJ. Representative Rodent Models for Renal Transporter Alterations in Human Nonalcoholic Steatohepatitis. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 37137719 DOI: 10.1124/dmd.122.001133 |
0.32 |
|
| 2023 |
Hau RK, Wright SH, Cherrington NJ. Drug Transporters at the Human Blood-Testis Barrier. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 36732077 DOI: 10.1124/dmd.122.001186 |
0.36 |
|
| 2022 |
Marie S, Frost KL, Hau RK, Martinez-Guerrero L, Izu JM, Myers CM, Wright SH, Cherrington NJ. Predicting disruptions to drug pharmacokinetics and the risk of adverse drug reactions in non-alcoholic steatohepatitis patients. Acta Pharmaceutica Sinica. B. 13: 1-28. PMID 36815037 DOI: 10.1016/j.apsb.2022.08.018 |
0.38 |
|
| 2022 |
Frost KL, Jilek JL, Sinari S, Klein RR, Billheimer D, Wright SH, Cherrington NJ. Renal Transporter Alterations in Patients with Chronic Liver Diseases: Nonalcoholic Steatohepatitis, Alcohol-associated, Viral Hepatitis, and Alcohol-Viral Combination. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 36328481 DOI: 10.1124/dmd.122.001038 |
0.441 |
|
| 2022 |
Frost KL, Jilek JL, Thompson AD, Klein RR, Sinari S, Torabzedehkorasani E, Billheimer DD, Schnellmann RG, Cherrington NJ. Increased Renal Expression of Complement Components in Patients with Liver Diseases: Nonalcoholic Steatohepatitis, Alcohol-Associated, Viral Hepatitis, and Alcohol-Viral Combination. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 35789393 DOI: 10.1093/toxsci/kfac070 |
0.32 |
|
| 2021 |
Jilek JL, Frost KL, Jacobus KA, He W, Toth EL, Goedken M, Cherrington NJ. Altered cisplatin pharmacokinetics during nonalcoholic steatohepatitis contributes to reduced nephrotoxicity. Acta Pharmaceutica Sinica. B. 11: 3869-3878. PMID 35024313 DOI: 10.1016/j.apsb.2021.05.030 |
0.369 |
|
| 2021 |
Jilek JL, Frost KL, Marie S, Myers CM, Goedken M, Wright SH, Cherrington NJ. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 34921099 DOI: 10.1124/dmd.121.000451 |
0.31 |
|
| 2021 |
Marie S, Tripp DKK, Cherrington NJ. Exogenous Drug Disposition as a Diagnostic Biomarker Strategy for Non-Alcoholic Steatohepatitis. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 34531312 DOI: 10.1124/dmd.121.000413 |
0.337 |
|
| 2020 |
Letertre MPM, Munjoma N, Wolfer K, Pechlivanis A, McDonald JAK, Hardwick R, Cherrington NJ, Coen M, Nicholson JK, Hoyles L, Swann JR, Wilson ID. A two-way interaction between methotrexate and the gut microbiota of male Sprague Dawley rats. Journal of Proteome Research. PMID 32544340 DOI: 10.1021/Acs.Jproteome.0C00230 |
0.718 |
|
| 2020 |
Miller SR, Hau RK, Jilek JL, Morales MN, Wright SH, Cherrington NJ. Nucleoside Reverse Transcriptase Inhibitor (NRTI) Interaction with Human Equilibrative Nucleoside Transporters 1 and 2. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 32393653 DOI: 10.1124/Dmd.120.090720 |
0.387 |
|
| 2020 |
Hau RK, Wright SH, Cherrington NJ. Expression and Immunolocalization of Xenobiotic Transporters at the Human Blood‐Testis Barrier The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.08992 |
0.397 |
|
| 2020 |
Jilek JL, Toth E, Frost K, Jacobus K, He W, Goedken M, Cherrington N. Altered Cisplatin Pharmacokinetics during Nonalcoholic Steatohepatitis Contributes to Reduced Nephrotoxicity The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05732 |
0.382 |
|
| 2019 |
Toth EL, Clarke JD, Csanaky IL, Cherrington NJ. Interaction of Oatp1b2 Expression and Nonalcoholic Steatohepatitis on Pravastatin Plasma Clearance. Biochemical Pharmacology. 113780. PMID 31881192 DOI: 10.1016/J.Bcp.2019.113780 |
0.462 |
|
| 2019 |
Clarke JD, Dzierlenga A, Arman T, Toth E, Li H, Lynch KD, Tian DD, Goedken M, Paine MF, Cherrington N. Nonalcoholic fatty liver disease alters microcystin-LR toxicokinetics and acute toxicity. Toxicon : Official Journal of the International Society On Toxinology. PMID 30849452 DOI: 10.1016/J.Toxicon.2019.03.002 |
0.537 |
|
| 2019 |
Lake AD, Hardwick RN, Leamon CP, Low PS, Cherrington NJ. Folate receptor-beta expression as a diagnostic target in human & rodent nonalcoholic steatohepatitis. Toxicology and Applied Pharmacology. PMID 30794826 DOI: 10.1016/J.Taap.2019.02.009 |
0.823 |
|
| 2018 |
Miller SR, Cherrington NJ. Transepithelial transport across the blood–testis barrier Reproduction (Cambridge, England). PMID 30328342 DOI: 10.1530/Rep-18-0338 |
0.382 |
|
| 2018 |
Toth EL, Li H, Dzierlenga AL, Clarke JD, Vildhede A, Goedken M, Cherrington NJ. Gene-by-Environment Interaction of Bcrp-/- and MCD Diet-Induced Nonalcoholic Steatohepatitis Alters SN-38 Disposition. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 30166404 DOI: 10.1124/Dmd.118.082081 |
0.51 |
|
| 2018 |
Li H, Toth E, Cherrington NJ. Alcohol Metabolism in the Progression of Human Nonalcoholic Steatohepatitis. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 29718361 DOI: 10.1093/Toxsci/Kfy106 |
0.471 |
|
| 2018 |
Dzierlenga AL, Cherrington NJ. Misregulation of membrane trafficking processes in human nonalcoholic steatohepatitis. Journal of Biochemical and Molecular Toxicology. PMID 29341352 DOI: 10.1002/Jbt.22035 |
0.345 |
|
| 2017 |
Li H, Toth E, Cherrington NJ. Methionine and Choline Deficient (MCD) Model in Predicting Adverse Drug Reactions in Human NASH. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 29145614 DOI: 10.1093/Toxsci/Kfx253 |
0.39 |
|
| 2017 |
Li H, Mark CJ, Clarke JD, Billheimer D, Xanthakos SA, Lavine JE, Erickson RP, Cherrington NJ. Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28986475 DOI: 10.1124/Dmd.117.077644 |
0.447 |
|
| 2017 |
Lee S, Kim S, Hwang S, Cherrington NJ, Ryu DY. Dysregulated expression of proteins associated with ER stress, autophagy and apoptosis in tissues from nonalcoholic fatty liver disease. Oncotarget. 8: 63370-63381. PMID 28968997 DOI: 10.18632/Oncotarget.18812 |
0.439 |
|
| 2017 |
Lee S, Kim S, Hwang S, Cherrington NJ, Ryu DY. Dysregulated expression of proteins associated with ER stress, autophagy and apoptosis in tissues from nonalcoholic fatty liver disease. Oncotarget. PMID 28711933 DOI: 10.18632/oncotarget.18812 |
0.328 |
|
| 2017 |
Han J, Dzierlenga AL, Lu Z, Billheimer DD, Torabzadeh E, Lake AD, Li H, Novak P, Shipkova P, Aranibar N, Robertson D, Reily MD, Lehman-McKeeman LD, Cherrington NJ. Metabolomic profiling distinction of human nonalcoholic fatty liver disease progression from a common rat model. Obesity (Silver Spring, Md.). PMID 28452429 DOI: 10.1002/Oby.21855 |
0.815 |
|
| 2017 |
Yu AM, Ingelman-Sundberg M, Cherrington NJ, Aleksunes LM, Zanger UM, Xie W, Jeong H, Morgan EM, Turnbaugh PJ, Klaassen CD, Bhatt AP, Redinbo MR, Hao P, Waxman DJ, Wang L, et al. Regulation of drug metabolism and toxicity by multiple factors of genetics, epigenetics, lncRNAs, gut microbiota, and diseases: a meeting report of the 21(st) International Symposium on Microsomes and Drug Oxidations (MDO). Acta Pharmaceutica Sinica. B. 7: 241-248. PMID 28388695 DOI: 10.1016/J.Apsb.2016.12.006 |
0.393 |
|
| 2017 |
Klein DM, Harding MC, Crowther MK, Cherrington NJ. Localization of nucleoside transporters in rat epididymis. Journal of Biochemical and Molecular Toxicology. PMID 28322028 DOI: 10.1002/Jbt.21911 |
0.434 |
|
| 2017 |
Clarke JD, Novak P, Lake AD, Hardwick RN, Cherrington NJ. Impaired N-linked Glycosylation of Uptake and Efflux Transporters in Human Nonalcoholic Fatty Liver Disease. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 28097795 DOI: 10.1111/Liv.13362 |
0.843 |
|
| 2016 |
Lake AD, Chaput AL, Novak P, Cherrington NJ, Smith CL. Transcription factor binding site enrichment analysis predicts drivers of altered gene expression in nonalcoholic steatohepatitis. Biochemical Pharmacology. PMID 27836672 DOI: 10.1016/J.Bcp.2016.11.006 |
0.789 |
|
| 2016 |
Li H, Clarke JD, Dzierlenga AL, Bear J, Goedken MJ, Cherrington NJ. In vivo cytochrome P450 activity alterations in diabetic nonalcoholic steatohepatitis mice. Journal of Biochemical and Molecular Toxicology. PMID 27712037 DOI: 10.1002/Jbt.21840 |
0.405 |
|
| 2016 |
Dzierlenga AL, Clarke JD, Cherrington N. Nonalcoholic Steatohepatitis Modulates Membrane Protein Retrieval and Insertion Processes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 27604106 DOI: 10.1124/Dmd.116.071415 |
0.378 |
|
| 2016 |
Laho T, Clarke JD, Dzierlenga AL, Li H, Klein DM, Goedken M, Micuda S, Cherrington NJ. Effect of Nonalcoholic Steatohepatitis on Renal Filtration and Secretion of Adefovir. Biochemical Pharmacology. PMID 27381944 DOI: 10.1016/J.Bcp.2016.07.001 |
0.404 |
|
| 2016 |
Dzierlenga AL, Clarke JD, Klein DM, Anumol T, Snyder SA, Li HY, Cherrington N. Biliary Elimination of Pemetrexed is Dependent on Mrp2 in Rats: Potential Mechanism of Variable Response in Nonalcoholic Steatohepatitis. The Journal of Pharmacology and Experimental Therapeutics. PMID 27233293 DOI: 10.1124/Jpet.116.234310 |
0.536 |
|
| 2016 |
Ditzel EJ, Li H, Foy CE, Perrera AB, Parker P, Renquist BJ, Cherrington NJ, Camenisch TD. Altered Hepatic Transport by Fetal Arsenite Exposure in Diet-Induced Fatty Liver Disease. Journal of Biochemical and Molecular Toxicology. PMID 26890134 DOI: 10.1002/Jbt.21796 |
0.593 |
|
| 2016 |
Donepudi AC, Cheng Q, Lu ZJ, Cherrington NJ, Slitt AL. Hepatic Transporter Expression in Metabolic Syndrome: Phenotype, serum metabolic hormones, and transcription factor expression. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 26847773 DOI: 10.1124/Dmd.115.066779 |
0.432 |
|
| 2015 |
Clarke JD, Dzierlenga AL, Nelson NR, Li H, Werts S, Goedken MJ, Cherrington NJ. Mechanism of Altered Metformin Distribution in Nonalcoholic Steatohepatitis. Diabetes. PMID 26016715 DOI: 10.2337/Db14-1947 |
0.471 |
|
| 2015 |
Clarke JD, Cherrington NJ. Nonalcoholic steatohepatitis in precision medicine: Unraveling the factors that contribute to individual variability. Pharmacology & Therapeutics. 151: 99-106. PMID 25805597 DOI: 10.1016/J.Pharmthera.2015.03.005 |
0.376 |
|
| 2015 |
Canet MJ, Merrell MD, Hardwick RN, Bataille AM, Campion SN, Ferreira DW, Xanthakos SA, Manautou JE, Hesham A-Kader H, Erickson RP, Cherrington NJ. Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 829-35. PMID 25788542 DOI: 10.1124/Dmd.114.062703 |
0.84 |
|
| 2015 |
Lake AD, Novak P, Shipkova P, Aranibar N, Robertson DG, Reily MD, Lehman-McKeeman LD, Vaillancourt RR, Cherrington NJ. Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease. Amino Acids. 47: 603-15. PMID 25534430 DOI: 10.1007/S00726-014-1894-9 |
0.809 |
|
| 2015 |
Dzierlenga AL, Clarke JD, Hargraves TL, Ainslie GR, Vanderah TW, Paine MF, Cherrington NJ. Mechanistic basis of altered morphine disposition in nonalcoholic steatohepatitis. The Journal of Pharmacology and Experimental Therapeutics. 352: 462-70. PMID 25512370 DOI: 10.1124/Jpet.114.220764 |
0.393 |
|
| 2015 |
Canet MJ, Hardwick RN, Lake AD, Dzierlenga AL, Clarke JD, Goedken MJ, Cherrington NJ. Renal xenobiotic transporter expression is altered in multiple experimental models of nonalcoholic steatohepatitis. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 266-72. PMID 25488932 DOI: 10.1124/Dmd.114.060574 |
0.833 |
|
| 2015 |
Canet MJ, Merrell MD, Harder BG, Maher JM, Wu T, Lickteig AJ, Jackson JP, Zhang DD, Yamamoto M, Cherrington NJ. Identification of a functional antioxidant response element within the eighth intron of the human ABCC3 gene. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 93-9. PMID 25349122 DOI: 10.1124/Dmd.114.060103 |
0.77 |
|
| 2014 |
Klein DM, Cherrington NJ. Organic and inorganic transporters of the testis: A review. Spermatogenesis. 4: e979653. PMID 26413398 DOI: 10.4161/21565562.2014.979653 |
0.306 |
|
| 2014 |
Kyriakides M, Hardwick RN, Jin Z, Goedken MJ, Holmes E, Cherrington NJ, Coen M. Systems level metabolic phenotype of methotrexate administration in the context of non-alcoholic steatohepatitis in the rat. Toxicological Sciences : An Official Journal of the Society of Toxicology. 142: 105-16. PMID 25145655 DOI: 10.1093/Toxsci/Kfu160 |
0.792 |
|
| 2014 |
Hardwick RN, Clarke JD, Lake AD, Canet MJ, Anumol T, Street SM, Merrell MD, Goedken MJ, Snyder SA, Cherrington NJ. Increased susceptibility to methotrexate-induced toxicity in nonalcoholic steatohepatitis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 142: 45-55. PMID 25080921 DOI: 10.1093/Toxsci/Kfu156 |
0.814 |
|
| 2014 |
Canet MJ, Cherrington NJ. Drug disposition alterations in liver disease: extrahepatic effects in cholestasis and nonalcoholic steatohepatitis. Expert Opinion On Drug Metabolism & Toxicology. 10: 1209-19. PMID 24989624 DOI: 10.1517/17425255.2014.936378 |
0.803 |
|
| 2014 |
Klein DM, Wright SH, Cherrington NJ. Xenobiotic transporter expression along the male genital tract. Reproductive Toxicology (Elmsford, N.Y.). 47: 1-8. PMID 24814985 DOI: 10.1016/J.Reprotox.2014.04.009 |
0.414 |
|
| 2014 |
Clarke JD, Hardwick RN, Lake AD, Lickteig AJ, Goedken MJ, Klaassen CD, Cherrington NJ. Synergistic interaction between genetics and disease on pravastatin disposition. Journal of Hepatology. 61: 139-47. PMID 24613363 DOI: 10.1016/J.Jhep.2014.02.021 |
0.813 |
|
| 2014 |
Clarke JD, Hardwick RN, Lake AD, Canet MJ, Cherrington NJ. Experimental nonalcoholic steatohepatitis increases exposure to simvastatin hydroxy acid by decreasing hepatic organic anion transporting polypeptide expression. The Journal of Pharmacology and Experimental Therapeutics. 348: 452-8. PMID 24403518 DOI: 10.1124/Jpet.113.211284 |
0.851 |
|
| 2014 |
Canet MJ, Hardwick RN, Lake AD, Dzierlenga AL, Clarke JD, Cherrington NJ. Modeling human nonalcoholic steatohepatitis-associated changes in drug transporter expression using experimental rodent models. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 586-95. PMID 24384915 DOI: 10.1124/Dmd.113.055996 |
0.829 |
|
| 2014 |
Merrell MD, Nyagode BA, Clarke JD, Cherrington NJ, Morgan ET. Selective and cytokine-dependent regulation of hepatic transporters and bile acid homeostasis during infectious colitis in mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 596-602. PMID 24378326 DOI: 10.1124/Dmd.113.055525 |
0.839 |
|
| 2014 |
Clarke JD, Sharapova T, Lake AD, Blomme E, Maher J, Cherrington NJ. Circulating microRNA 122 in the methionine and choline-deficient mouse model of non-alcoholic steatohepatitis. Journal of Applied Toxicology : Jat. 34: 726-32. PMID 24217942 DOI: 10.1002/Jat.2960 |
0.781 |
|
| 2014 |
Klein DM, Wright SH, Cherrington NJ. Localization of multidrug resistance-associated proteins along the blood-testis barrier in rat, macaque, and human testis. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 89-93. PMID 24130369 DOI: 10.1124/Dmd.113.054577 |
0.434 |
|
| 2014 |
Lake AD, Novak P, Hardwick RN, Flores-Keown B, Zhao F, Klimecki WT, Cherrington NJ. The adaptive endoplasmic reticulum stress response to lipotoxicity in progressive human nonalcoholic fatty liver disease. Toxicological Sciences : An Official Journal of the Society of Toxicology. 137: 26-35. PMID 24097666 DOI: 10.1093/Toxsci/Kft230 |
0.819 |
|
| 2014 |
Clarke JD, Novak P, Lake AD, Shipkova P, Aranibar N, Robertson D, Severson PL, Reily MD, Futscher BW, Lehman-McKeeman LD, Cherrington NJ. Characterization of hepatocellular carcinoma related genes and metabolites in human nonalcoholic fatty liver disease. Digestive Diseases and Sciences. 59: 365-74. PMID 24048683 DOI: 10.1007/S10620-013-2873-9 |
0.768 |
|
| 2013 |
Bodeman CE, Dzierlenga AL, Tally CM, Mulligan RM, Lake AD, Cherrington NJ, McKarns SC. Differential regulation of hepatic organic cation transporter 1, organic anion-transporting polypeptide 1a4, bile-salt export pump, and multidrug resistance-associated protein 2 transporter expression in lymphocyte-deficient mice associates with interleukin-6 production. The Journal of Pharmacology and Experimental Therapeutics. 347: 136-44. PMID 23929842 DOI: 10.1124/Jpet.113.205369 |
0.781 |
|
| 2013 |
Yalcin EB, More V, Neira KL, Lu ZJ, Cherrington NJ, Slitt AL, King RS. Downregulation of sulfotransferase expression and activity in diseased human livers. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 1642-50. PMID 23775849 DOI: 10.1124/Dmd.113.050930 |
0.507 |
|
| 2013 |
Klein DM, Evans KK, Hardwick RN, Dantzler WH, Wright SH, Cherrington NJ. Basolateral uptake of nucleosides by Sertoli cells is mediated primarily by equilibrative nucleoside transporter 1. The Journal of Pharmacology and Experimental Therapeutics. 346: 121-9. PMID 23639800 DOI: 10.1124/Jpet.113.203265 |
0.743 |
|
| 2013 |
More VR, Cheng Q, Donepudi AC, Buckley DB, Lu ZJ, Cherrington NJ, Slitt AL. Alcohol cirrhosis alters nuclear receptor and drug transporter expression in human liver. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 1148-55. PMID 23462698 DOI: 10.1124/Dmd.112.049676 |
0.514 |
|
| 2013 |
Lake AD, Novak P, Shipkova P, Aranibar N, Robertson D, Reily MD, Lu Z, Lehman-McKeeman LD, Cherrington NJ. Decreased hepatotoxic bile acid composition and altered synthesis in progressive human nonalcoholic fatty liver disease. Toxicology and Applied Pharmacology. 268: 132-40. PMID 23391614 DOI: 10.1016/J.Taap.2013.01.022 |
0.831 |
|
| 2013 |
Hardwick RN, Ferreira DW, More VR, Lake AD, Lu Z, Manautou JE, Slitt AL, Cherrington NJ. Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver disease. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 554-61. PMID 23223517 DOI: 10.1124/Dmd.112.048439 |
0.843 |
|
| 2013 |
Cherrington NJ, Estrada TE, Frisk HA, Canet MJ, Hardwick RN, Dvorak B, Lux K, Halpern MD. The hepatic bile acid transporters Ntcp and Mrp2 are downregulated in experimental necrotizing enterocolitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 304: G48-56. PMID 23125159 DOI: 10.1152/Ajpgi.00317.2012 |
0.832 |
|
| 2012 |
Canet MJ, Hardwick RN, Lake AD, Kopplin MJ, Scheffer GL, Klimecki WT, Gandolfi AJ, Cherrington NJ. Altered arsenic disposition in experimental nonalcoholic fatty liver disease. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 1817-24. PMID 22699396 DOI: 10.1124/Dmd.112.046177 |
0.841 |
|
| 2012 |
Hardwick RN, Cherrington NJ. Measuring altered disposition of xenobiotics in experimental models of liver disease. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit 23.1.. PMID 22549269 DOI: 10.1002/0471140856.Tx2301S52 |
0.798 |
|
| 2012 |
Clarke JD, Cherrington NJ. Genetics or environment in drug transport: the case of organic anion transporting polypeptides and adverse drug reactions. Expert Opinion On Drug Metabolism & Toxicology. 8: 349-60. PMID 22280100 DOI: 10.1517/17425255.2012.656087 |
0.533 |
|
| 2012 |
Hardwick RN, Fisher CD, Street SM, Canet MJ, Cherrington NJ. Molecular mechanism of altered ezetimibe disposition in nonalcoholic steatohepatitis. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 450-60. PMID 22112382 DOI: 10.1124/Dmd.111.041095 |
0.835 |
|
| 2012 |
Jelinek DA, Maghsoodi B, Borbon IA, Hardwick RN, Cherrington NJ, Erickson RP. Genetic variation in the mouse model of Niemann Pick C1 affects female, as well as male, adiposity, and hepatic bile transporters but has indeterminate effects on caveolae. Gene. 491: 128-34. PMID 22020183 DOI: 10.1016/J.Gene.2011.10.010 |
0.741 |
|
| 2011 |
Hardwick RN, Fisher CD, Canet MJ, Scheffer GL, Cherrington NJ. Variations in ATP-binding cassette transporter regulation during the progression of human nonalcoholic fatty liver disease. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 2395-402. PMID 21878559 DOI: 10.1124/Dmd.111.041012 |
0.852 |
|
| 2011 |
Lake AD, Novak P, Fisher CD, Jackson JP, Hardwick RN, Billheimer DD, Klimecki WT, Cherrington NJ. Analysis of global and absorption, distribution, metabolism, and elimination gene expression in the progressive stages of human nonalcoholic fatty liver disease. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 1954-60. PMID 21737566 DOI: 10.1124/Dmd.111.040592 |
0.842 |
|
| 2011 |
Merrell MD, Cherrington NJ. Drug metabolism alterations in nonalcoholic fatty liver disease. Drug Metabolism Reviews. 43: 317-34. PMID 21612324 DOI: 10.3109/03602532.2011.577781 |
0.844 |
|
| 2011 |
Cheng Q, Taguchi K, Aleksunes LM, Manautou JE, Cherrington NJ, Yamamoto M, Slitt AL. Constitutive activation of nuclear factor-E2-related factor 2 induces biotransformation enzyme and transporter expression in livers of mice with hepatocyte-specific deletion of Kelch-like ECH-associated protein 1. Journal of Biochemical and Molecular Toxicology. 25: 320-9. PMID 21538727 DOI: 10.1002/Jbt.20392 |
0.556 |
|
| 2010 |
Hardwick RN, Fisher CD, Canet MJ, Lake AD, Cherrington NJ. Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 2293-301. PMID 20805291 DOI: 10.1124/Dmd.110.035006 |
0.816 |
|
| 2010 |
Genter MB, Krishan M, Augustine LM, Cherrington NJ. Drug transporter expression and localization in rat nasal respiratory and olfactory mucosa and olfactory bulb. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 1644-7. PMID 20660103 DOI: 10.1124/Dmd.110.034611 |
0.385 |
|
| 2010 |
A-Kader HH, Merrell MD, Erickson R, Cherrington N. S1840 Acetaminophen Disposition: A Novel Marker for Patients With Nonalcoholic Fatty Liver Disease Gastroenterology. 138: S-800. DOI: 10.1016/S0016-5085(10)63687-6 |
0.825 |
|
| 2009 |
Fisher CD, Lickteig AJ, Augustine LM, Ranger-Moore J, Jackson JP, Ferguson SS, Cherrington NJ. Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 2087-94. PMID 19651758 DOI: 10.1124/Dmd.109.027466 |
0.835 |
|
| 2009 |
Beilke LD, Aleksunes LM, Olson ER, Besselsen DG, Klaassen CD, Dvorak K, Cherrington NJ. Decreased apoptosis during CAR-mediated hepatoprotection against lithocholic acid-induced liver injury in mice. Toxicology Letters. 188: 38-44. PMID 19433268 DOI: 10.1016/J.Toxlet.2009.03.005 |
0.825 |
|
| 2009 |
Campion SN, Tatis-Rios C, Augustine LM, Goedken MJ, van Rooijen N, Cherrington NJ, Manautou JE. Effect of allyl alcohol on hepatic transporter expression: zonal patterns of expression and role of Kupffer cell function. Toxicology and Applied Pharmacology. 236: 49-58. PMID 19371622 DOI: 10.1016/J.Taap.2009.01.007 |
0.533 |
|
| 2009 |
Fisher CD, Lickteig AJ, Augustine LM, Oude Elferink RP, Besselsen DG, Erickson RP, Cherrington NJ. Experimental non-alcoholic fatty liver disease results in decreased hepatic uptake transporter expression and function in rats. European Journal of Pharmacology. 613: 119-27. PMID 19358839 DOI: 10.1016/J.Ejphar.2009.04.002 |
0.856 |
|
| 2009 |
Beilke LD, Aleksunes LM, Holland RD, Besselsen DG, Beger RD, Klaassen CD, Cherrington NJ. Constitutive androstane receptor-mediated changes in bile acid composition contributes to hepatoprotection from lithocholic acid-induced liver injury in mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 1035-45. PMID 19196849 DOI: 10.1124/Dmd.108.023317 |
0.823 |
|
| 2008 |
Das PC, Cao Y, Rose RL, Cherrington N, Hodgson E. Enzyme induction and cytotoxicity in human hepatocytes by chlorpyrifos and N,N-diethyl-m-toluamide (DEET). Drug Metabolism and Drug Interactions. 23: 237-60. PMID 19326769 DOI: 10.1515/Dmdi.2008.23.3-4.237 |
0.434 |
|
| 2008 |
Das PC, Streit TM, Cao Y, Rose RL, Cherrington N, Ross MK, Wallace AD, Hodgson E. Pyrethroids: cytotoxicity and induction of CYP isoforms in human hepatocytes. Drug Metabolism and Drug Interactions. 23: 211-36. PMID 19326768 DOI: 10.1515/Dmdi.2008.23.3-4.211 |
0.373 |
|
| 2008 |
Aleksunes LM, Augustine LM, Scheffer GL, Cherrington NJ, Manautou JE. Renal xenobiotic transporters are differentially expressed in mice following cisplatin treatment. Toxicology. 250: 82-8. PMID 18640236 DOI: 10.1016/J.Tox.2008.06.009 |
0.418 |
|
| 2008 |
Lickteig AJ, Cheng X, Augustine LM, Klaassen CD, Cherrington NJ. Tissue distribution, ontogeny and induction of the transporters Multidrug and toxin extrusion (MATE) 1 and MATE2 mRNA expression levels in mice. Life Sciences. 83: 59-64. PMID 18573474 DOI: 10.1016/J.Lfs.2008.05.004 |
0.773 |
|
| 2008 |
Campion SN, Johnson R, Aleksunes LM, Goedken MJ, van Rooijen N, Scheffer GL, Cherrington NJ, Manautou JE. Hepatic Mrp4 induction following acetaminophen exposure is dependent on Kupffer cell function. American Journal of Physiology. Gastrointestinal and Liver Physiology. 295: G294-304. PMID 18556419 DOI: 10.1152/Ajpgi.00541.2007 |
0.556 |
|
| 2008 |
Fisher CD, Jackson JP, Lickteig AJ, Augustine LM, Cherrington NJ. Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis Archives of Toxicology. 82: 959-964. PMID 18488193 DOI: 10.1007/S00204-008-0312-Z |
0.829 |
|
| 2008 |
Merrell MD, Jackson JP, Augustine LM, Fisher CD, Slitt AL, Maher JM, Huang W, Moore DD, Zhang Y, Klaassen CD, Cherrington NJ. The Nrf2 activator oltipraz also activates the constitutive androstane receptor. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 1716-21. PMID 18474683 DOI: 10.1124/Dmd.108.020867 |
0.826 |
|
| 2008 |
Augustine LM, Fisher CD, Lickteig AJ, Aleksunes LM, Slitt AL, Cherrington NJ. Gender divergent expression of Nqo1 in Sprague Dawley and August Copenhagen x Irish rats. Journal of Biochemical and Molecular Toxicology. 22: 93-100. PMID 18418895 DOI: 10.1002/Jbt.20224 |
0.802 |
|
| 2008 |
Merrell MD, Augustine LM, Slitt AL, Cherrington NJ. Induction of drug metabolism enzymes and transporters by oltipraz in rats. Journal of Biochemical and Molecular Toxicology. 22: 128-35. PMID 18418891 DOI: 10.1002/Jbt.20225 |
0.83 |
|
| 2008 |
Cheng Q, Aleksunes LM, Manautou JE, Cherrington NJ, Scheffer GL, Yamasaki H, Slitt AL. Drug-metabolizing enzyme and transporter expression in a mouse model of diabetes and obesity. Molecular Pharmaceutics. 5: 77-91. PMID 18189363 DOI: 10.1021/Mp700114J |
0.54 |
|
| 2008 |
Beilke LD, Besselsen DG, Cheng Q, Kulkarni S, Slitt AL, Cherrington NJ. Minimal role of hepatic transporters in the hepatoprotection against LCA-induced intrahepatic cholestasis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 102: 196-204. PMID 18032408 DOI: 10.1093/Toxsci/Kfm287 |
0.836 |
|
| 2008 |
Aleksunes LM, Slitt AL, Maher JM, Augustine LM, Goedken MJ, Chan JY, Cherrington NJ, Klaassen CD, Manautou JE. Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2. Toxicology and Applied Pharmacology. 226: 74-83. PMID 17935745 DOI: 10.1016/J.Taap.2007.08.022 |
0.517 |
|
| 2007 |
Aleksunes LM, Augustine LM, Cherrington NJ, Manautou JE. Influence of acetaminophen vehicle on regulation of transporter gene expression during hepatotoxicity. Journal of Toxicology and Environmental Health. Part A. 70: 1870-2. PMID 17934960 DOI: 10.1080/15287390701457662 |
0.491 |
|
| 2007 |
Lickteig AJ, Fisher CD, Augustine LM, Cherrington NJ. Genes of the antioxidant response undergo upregulation in a rodent model of nonalcoholic steatohepatitis. Journal of Biochemical and Molecular Toxicology. 21: 216-20. PMID 17721935 DOI: 10.1002/Jbt.20177 |
0.846 |
|
| 2007 |
Lickteig AJ, Fisher CD, Augustine LM, Aleksunes LM, Besselsen DG, Slitt AL, Manautou JE, Cherrington NJ. Efflux transporter expression and acetaminophen metabolite excretion are altered in rodent models of nonalcoholic fatty liver disease. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 1970-8. PMID 17640958 DOI: 10.1124/Dmd.107.015107 |
0.865 |
|
| 2007 |
Barnes SN, Aleksunes LM, Augustine L, Scheffer GL, Goedken MJ, Jakowski AB, Pruimboom-Brees IM, Cherrington NJ, Manautou JE. Induction of hepatobiliary efflux transporters in acetaminophen-induced acute liver failure cases. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 1963-9. PMID 17627974 DOI: 10.1124/Dmd.107.016170 |
0.557 |
|
| 2007 |
Fisher CD, Augustine LM, Maher JM, Nelson DM, Slitt AL, Klaassen CD, Lehman-McKeeman LD, Cherrington NJ. Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 995-1000. PMID 17353348 DOI: 10.1124/Dmd.106.014340 |
0.758 |
|
| 2007 |
Lickteig AJ, Slitt AL, Arkan MC, Karin M, Cherrington NJ. Differential regulation of hepatic transporters in the absence of tumor necrosis factor-alpha, interleukin-1beta, interleukin-6, and nuclear factor-kappaB in two models of cholestasis. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 402-9. PMID 17151194 DOI: 10.1124/Dmd.106.012138 |
0.8 |
|
| 2007 |
Slitt AL, Allen K, Morrone J, Aleksunes LM, Chen C, Maher JM, Manautou JE, Cherrington NJ, Klaassen CD. Regulation of transporter expression in mouse liver, kidney, and intestine during extrahepatic cholestasis. Biochimica Et Biophysica Acta. 1768: 637-47. PMID 17141734 DOI: 10.1016/J.Bbamem.2006.10.008 |
0.56 |
|
| 2006 |
Aleksunes LM, Slitt AL, Maher JM, Dieter MZ, Knight TR, Goedken M, Cherrington NJ, Chan JY, Klaassen CD, Manautou JE. Nuclear factor-E2-related factor 2 expression in liver is critical for induction of NAD(P)H:quinone oxidoreductase 1 during cholestasis. Cell Stress & Chaperones. 11: 356-63. PMID 17278884 DOI: 10.1379/Csc-217.1 |
0.532 |
|
| 2006 |
Das PC, Cao Y, Cherrington N, Hodgson E, Rose RL. Fipronil induces CYP isoforms and cytotoxicity in human hepatocytes. Chemico-Biological Interactions. 164: 200-14. PMID 17084830 DOI: 10.1016/J.Cbi.2006.09.013 |
0.368 |
|
| 2006 |
Slitt AL, Cherrington NJ, Fisher CD, Negishi M, Klaassen CD. Induction of genes for metabolism and transport by trans-stilbene oxide in livers of Sprague-Dawley and Wistar-Kyoto rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 1190-7. PMID 16621935 DOI: 10.1124/Dmd.105.007542 |
0.818 |
|
| 2006 |
Slitt AL, Cherrington NJ, Dieter MZ, Aleksunes LM, Scheffer GL, Huang W, Moore DD, Klaassen CD. trans-Stilbene oxide induces expression of genes involved in metabolism and transport in mouse liver via CAR and Nrf2 transcription factors. Molecular Pharmacology. 69: 1554-63. PMID 16449384 DOI: 10.1124/Mol.105.014571 |
0.58 |
|
| 2006 |
Maher JM, Cherrington NJ, Slitt AL, Klaassen CD. Tissue distribution and induction of the rat multidrug resistance-associated proteins 5 and 6. Life Sciences. 78: 2219-25. PMID 16260000 DOI: 10.1016/J.Lfs.2005.09.016 |
0.513 |
|
| 2006 |
Groves CE, Suhre WB, Cherrington NJ, Wright SH. Sex differences in the mRNA, protein, and functional expression of organic anion transporter (Oat) 1, Oat3, and organic cation transporter (Oct) 2 in rabbit renal proximal tubules. The Journal of Pharmacology and Experimental Therapeutics. 316: 743-52. PMID 16249371 DOI: 10.1124/Jpet.105.094979 |
0.403 |
|
| 2005 |
Maher JM, Slitt AL, Cherrington NJ, Cheng X, Klaassen CD. Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 947-55. PMID 15802388 DOI: 10.1124/Dmd.105.003780 |
0.491 |
|
| 2005 |
Erickson RP, Bhattacharyya A, Hunter RJ, Heidenreich RA, Cherrington NJ. Liver disease with altered bile acid transport in Niemann-Pick C mice on a high-fat, 1% cholesterol diet. American Journal of Physiology. Gastrointestinal and Liver Physiology. 289: G300-7. PMID 15790756 DOI: 10.1152/Ajpgi.00568.2004 |
0.431 |
|
| 2005 |
Aleksunes LM, Slitt AM, Cherrington NJ, Thibodeau MS, Klaassen CD, Manautou JE. Differential expression of mouse hepatic transporter genes in response to acetaminophen and carbon tetrachloride. Toxicological Sciences : An Official Journal of the Society of Toxicology. 83: 44-52. PMID 15496496 DOI: 10.1093/Toxsci/Kfi013 |
0.575 |
|
| 2005 |
Augustine LM, Markelewicz RJ, Boekelheide K, Cherrington NJ. Xenobiotic and endobiotic transporter mRNA expression in the blood-testis barrier. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 182-9. PMID 15494472 DOI: 10.1124/Dmd.104.001024 |
0.463 |
|
| 2004 |
Cherrington NJ, Slitt AL, Li N, Klaassen CD. Lipopolysaccharide-mediated regulation of hepatic transporter mRNA levels in rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 734-41. PMID 15205389 DOI: 10.1124/Dmd.32.7.734 |
0.469 |
|
| 2004 |
Wright SH, Evans KK, Zhang X, Cherrington NJ, Sitar DS, Dantzler WH. Functional map of TEA transport activity in isolated rabbit renal proximal tubules. American Journal of Physiology. Renal Physiology. 287: F442-51. PMID 15126247 DOI: 10.1152/Ajprenal.00115.2004 |
0.328 |
|
| 2004 |
Li N, Choudhuri S, Cherrington NJ, Klaassen CD. DOWN-REGULATION OF MOUSE ORGANIC ANION-TRANSPORTING POLYPEPTIDE 4 (Oatp4; Oatp1b2; Slc21a10) mRNA BY LIPOPOLYSACCHARIDE THROUGH THE TOLL-LIKE RECEPTOR 4 (TLR4) Drug Metabolism and Disposition. 32: 1265-1271. DOI: 10.1124/Dmd.32.11.1265 |
0.322 |
|
| 2003 |
Choudhuri S, Cherrington NJ, Li N, Klaassen CD. Constitutive expression of various xenobiotic and endobiotic transporter mRNAs in the choroid plexus of rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 1337-45. PMID 14570765 DOI: 10.1124/Dmd.31.11.1337 |
0.475 |
|
| 2003 |
Cherrington NJ, Slitt AL, Maher JM, Zhang XX, Zhang J, Huang W, Wan YJ, Moore DD, Klaassen CD. Induction of multidrug resistance protein 3 (mrp3) in vivo is independent of constitutive androstane receptor. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 1315-9. PMID 14570762 DOI: 10.1124/Dmd.31.11.1315 |
0.452 |
|
| 2003 |
Slitt AL, Cherrington NJ, Maher JM, Klaassen CD. Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 1176-86. PMID 12920174 DOI: 10.1124/Dmd.31.9.1176 |
0.515 |
|
| 2003 |
Buist SC, Cherrington NJ, Klaassen CD. Endocrine regulation of rat organic anion transporters. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 559-64. PMID 12695343 DOI: 10.1124/Dmd.31.5.559 |
0.386 |
|
| 2003 |
Shelby MK, Cherrington NJ, Vansell NR, Klaassen CD. Tissue mRNA expression of the rat UDP-glucuronosyltransferase gene family. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 326-33. PMID 12584160 DOI: 10.1124/Dmd.31.3.326 |
0.402 |
|
| 2002 |
Park JD, Cherrington NJ, Klaassen CD. Intestinal absorption of cadmium is associated with divalent metal transporter 1 in rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 68: 288-94. PMID 12151624 DOI: 10.1093/Toxsci/68.2.288 |
0.339 |
|
| 2002 |
Brady JM, Cherrington NJ, Hartley DP, Buist SC, Li N, Klaassen CD. Tissue distribution and chemical induction of multiple drug resistance genes in rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 30: 838-44. PMID 12065443 DOI: 10.1124/Dmd.30.7.838 |
0.477 |
|
| 2002 |
Li N, Hartley DP, Cherrington NJ, Klaassen CD. Tissue expression, ontogeny, and inducibility of rat organic anion transporting polypeptide 4. The Journal of Pharmacology and Experimental Therapeutics. 301: 551-60. PMID 11961056 DOI: 10.1124/Jpet.301.2.551 |
0.557 |
|
| 2002 |
Buist SC, Cherrington NJ, Choudhuri S, Hartley DP, Klaassen CD. Gender-specific and developmental influences on the expression of rat organic anion transporters. The Journal of Pharmacology and Experimental Therapeutics. 301: 145-51. PMID 11907168 DOI: 10.1124/Jpet.301.1.145 |
0.43 |
|
| 2002 |
Slitt AL, Cherrington NJ, Hartley DP, Leazer TM, Klaassen CD. Tissue distribution and renal developmental changes in rat organic cation transporter mRNA levels. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 30: 212-9. PMID 11792693 DOI: 10.1124/Dmd.30.2.212 |
0.342 |
|
| 2002 |
Cherrington NJ, Hartley DP, Li N, Johnson DR, Klaassen CD. Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats. The Journal of Pharmacology and Experimental Therapeutics. 300: 97-104. PMID 11752103 DOI: 10.1124/Jpet.300.1.97 |
0.543 |
|
| 2001 |
Takiguchi M, Cherrington NJ, Hartley DP, Klaassen CD, Waalkes MP. Cyproterone acetate induces a cellular tolerance to cadmium in rat liver epithelial cells involving reduced cadmium accumulation. Toxicology. 165: 13-25. PMID 11551428 DOI: 10.1016/S0300-483X(01)00402-4 |
0.341 |
|
| 1998 |
Cherrington NJ, Cao Y, Cherrington JW, Rose RL, Hodgson E. Physiological factors affecting protein expression of flavin-containing monooxygenases 1, 3 and 5. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 28: 673-82. PMID 9711811 DOI: 10.1080/004982598239254 |
0.38 |
|
| 1998 |
Cherrington NJ, Falls JG, Rose RL, Clements KM, Philpot RM, Levi PE, Hodgson E. Molecular cloning, sequence, and expression of mouse flavin-containing monooxygenases 1 and 5 (FMO1 and FMO5). Journal of Biochemical and Molecular Toxicology. 12: 205-12. PMID 9580872 DOI: 10.1002/(Sici)1099-0461(1998)12:4<205::Aid-Jbt2>3.0.Co;2-P |
0.328 |
|
| 1997 |
Falls JG, Cherrington NJ, Clements KM, Philpot RM, Levi PE, Rose RL, Hodgson E. Molecular cloning, sequencing, and expression in Escherichia coli of mouse flavin-containing monooxygenase 3 (FMO3): comparison with the human isoform. Archives of Biochemistry and Biophysics. 347: 9-18. PMID 9344459 DOI: 10.1006/Abbi.1997.0322 |
0.38 |
|
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