Charles D. Loftin - Publications

Affiliations: 
University of Kentucky, Lexington, KY 
Area:
Pharmacology, Pharmacy, Molecular Biology

13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Ding K, Zhou Z, Hou S, Yuan Y, Zhou S, Zheng X, Chen J, Loftin C, Zheng F, Zhan CG. Structure-based discovery of mPGES-1 inhibitors suitable for preclinical testing in wild-type mice as a new generation of anti-inflammatory drugs. Scientific Reports. 8: 5205. PMID 29581541 DOI: 10.1038/S41598-018-23482-4  0.339
2016 Adedoyin OO, Loftin CD. Microsomal Prostaglandin E Synthase-1 Expression by Aortic Smooth Muscle Cells Attenuates the Differentiated Phenotype. Journal of Cardiovascular Pharmacology. PMID 27159620 DOI: 10.1097/Fjc.0000000000000395  0.348
2014 Oestreich JH, Steinhubl SR, Ferraris SP, Loftin CD, Akers WS. Effect of genetic variation in P2Y12 on TRAP-stimulated platelet response in healthy subjects. Journal of Thrombosis and Thrombolysis. 38: 372-9. PMID 24510678 DOI: 10.1007/S11239-014-1058-5  0.45
2013 Trivedi DB, Loftin CD, Clark J, Myers P, DeGraff LM, Cheng J, Zeldin DC, Langenbach R. β-Arrestin-2 deficiency attenuates abdominal aortic aneurysm formation in mice. Circulation Research. 112: 1219-29. PMID 23524589 DOI: 10.1161/Circresaha.112.280399  0.37
2012 Ghoshal S, Loftin CD. Cyclooxygenase-2 inhibition attenuates abdominal aortic aneurysm progression in hyperlipidemic mice. Plos One. 7: e44369. PMID 23209546 DOI: 10.1371/Journal.Pone.0044369  0.383
2012 Mukherjee K, Gitlin JM, Loftin CD. Effectiveness of cyclooxygenase-2 inhibition in limiting abdominal aortic aneurysm progression in mice correlates with a differentiated smooth muscle cell phenotype. Journal of Cardiovascular Pharmacology. 60: 520-9. PMID 22967986 DOI: 10.1097/Fjc.0B013E318270B968  0.373
2011 Ghoshal S, Trivedi DB, Graf GA, Loftin CD. Cyclooxygenase-2 deficiency attenuates adipose tissue differentiation and inflammation in mice. The Journal of Biological Chemistry. 286: 889-98. PMID 20961858 DOI: 10.1074/Jbc.M110.139139  0.32
2009 Kelso ML, Scheff SW, Pauly JR, Loftin CD. Effects of genetic deficiency of cyclooxygenase-1 or cyclooxygenase-2 on functional and histological outcomes following traumatic brain injury in mice. Bmc Neuroscience. 10: 108. PMID 19719848 DOI: 10.1186/1471-2202-10-108  0.312
2009 Gitlin JM, Loftin CD. Cyclooxygenase-2 inhibition increases lipopolysaccharide-induced atherosclerosis in mice. Cardiovascular Research. 81: 400-7. PMID 18948273 DOI: 10.1093/Cvr/Cvn286  0.312
2007 Gitlin JM, Trivedi DB, Langenbach R, Loftin CD. Genetic deficiency of cyclooxygenase-2 attenuates abdominal aortic aneurysm formation in mice. Cardiovascular Research. 73: 227-36. PMID 17137566 DOI: 10.1016/J.Cardiores.2006.10.015  0.336
2006 Trivedi DB, Sugimoto Y, Loftin CD. Attenuated cyclooxygenase-2 expression contributes to patent ductus arteriosus in preterm mice. Pediatric Research. 60: 669-74. PMID 17065565 DOI: 10.1203/01.Pdr.0000246480.13170.C0  0.331
2006 King VL, Trivedi DB, Gitlin JM, Loftin CD. Selective cyclooxygenase-2 inhibition with celecoxib decreases angiotensin II-induced abdominal aortic aneurysm formation in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1137-43. PMID 16514081 DOI: 10.1161/01.Atv.0000216119.79008.Ac  0.385
2004 Gray T, Nettesheim P, Loftin C, Koo JS, Bonner J, Peddada S, Langenbach R. Interleukin-1beta-induced mucin production in human airway epithelium is mediated by cyclooxygenase-2, prostaglandin E2 receptors, and cyclic AMP-protein kinase A signaling. Molecular Pharmacology. 66: 337-46. PMID 15266025 DOI: 10.1124/Mol.66.2.337  0.301
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