| Year |
Citation |
Score |
| 2023 |
Ohtonen S, Giudice L, Jäntti H, Fazaludeen MF, Shakirzyanova A, Gómez-Budia M, Välimäki NN, Niskanen J, Korvenlaita N, Fagerlund I, Koistinaho J, Amiry-Moghaddam M, Savchenko E, Roybon L, Lehtonen Š, et al. Human iPSC-derived microglia carrying the LRRK2-G2019S mutation show a Parkinson's disease related transcriptional profile and function. Scientific Reports. 13: 22118. PMID 38092815 DOI: 10.1038/s41598-023-49294-9 |
0.591 |
|
| 2021 |
Keuters MH, Keksa-Goldsteine V, Dhungana H, Huuskonen MT, Pomeshchik Y, Savchenko E, Korhonen PK, Singh Y, Wojciechowski S, Lehtonen Š, Kanninen KM, Malm T, Sirviö J, Muona A, Koistinaho M, ... ... Koistinaho J, et al. An arylthiazyne derivative is a potent inhibitor of lipid peroxidation and ferroptosis providing neuroprotection in vitro and in vivo. Scientific Reports. 11: 3518. PMID 33568697 DOI: 10.1038/s41598-021-81741-3 |
0.731 |
|
| 2020 |
Rolova T, Wu YC, Koskuvi M, Voutilainen J, Sonninen TM, Kuusisto J, Laakso M, Hämäläinen RH, Koistinaho J, Lehtonen Š. Generation of a human induced pluripotent stem cell line (UEFi003-A) carrying heterozygous A673T variant in amyloid precursor protein associated with a reduced risk of Alzheimer's disease. Stem Cell Research. 48: 101968. PMID 32911327 DOI: 10.1016/J.Scr.2020.101968 |
0.323 |
|
| 2020 |
Sonninen TM, Hämäläinen RH, Koskuvi M, Oksanen M, Shakirzyanova A, Wojciechowski S, Puttonen K, Naumenko N, Goldsteins G, Laham-Karam N, Lehtonen M, Tavi P, Koistinaho J, Lehtonen Š. Metabolic alterations in Parkinson's disease astrocytes. Scientific Reports. 10: 14474. PMID 32879386 DOI: 10.1038/S41598-020-71329-8 |
0.309 |
|
| 2020 |
Kolosowska N, Gotkiewicz M, Dhungana H, Giudice L, Giugno R, Box D, Huuskonen MT, Korhonen P, Scoyni F, Kanninen KM, Ylä-Herttuala S, Turunen TA, Turunen MP, Koistinaho J, Malm T. Intracerebral overexpression of miR-669c is protective in mouse ischemic stroke model by targeting MyD88 and inducing alternative microglial/macrophage activation. Journal of Neuroinflammation. 17: 194. PMID 32560730 DOI: 10.1186/S12974-020-01870-W |
0.306 |
|
| 2020 |
Oikari LE, Pandit R, Stewart R, Cuní-López C, Quek H, Sutharsan R, Rantanen LM, Oksanen M, Lehtonen S, de Boer CM, Polo JM, Götz J, Koistinaho J, White AR. Altered Brain Endothelial Cell Phenotype from a Familial Alzheimer Mutation and Its Potential Implications for Amyloid Clearance and Drug Delivery. Stem Cell Reports. PMID 32275861 DOI: 10.1016/J.Stemcr.2020.03.011 |
0.337 |
|
| 2019 |
Oksanen M, Hyötyläinen I, Trontti K, Rolova T, Wojciechowski S, Koskuvi M, Viitanen M, Levonen AL, Hovatta I, Roybon L, Lehtonen Š, Kanninen KM, Hämäläinen RH, Koistinaho J. NF-E2-related factor 2 activation boosts antioxidant defenses and ameliorates inflammatory and amyloid properties in human Presenilin-1 mutated Alzheimer's disease astrocytes. Glia. PMID 31670864 DOI: 10.1002/Glia.23741 |
0.667 |
|
| 2019 |
Konttinen H, Cabral-da-Silva MEC, Ohtonen S, Wojciechowski S, Shakirzyanova A, Caligola S, Giugno R, Ishchenko Y, Hernández D, Fazaludeen MF, Eamen S, Budia MG, Fagerlund I, Scoyni F, Korhonen P, ... ... Koistinaho J, et al. PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia. Stem Cell Reports. PMID 31522977 DOI: 10.1016/J.Stemcr.2019.08.004 |
0.346 |
|
| 2019 |
Tiihonen J, Koskuvi M, Lähteenvuo M, Virtanen PLJ, Ojansuu I, Vaurio O, Gao Y, Hyötyläinen I, Puttonen KA, Repo-Tiihonen E, Paunio T, Rautiainen MR, Tyni S, Koistinaho J, Lehtonen Š. Neurobiological roots of psychopathy. Molecular Psychiatry. PMID 31455857 DOI: 10.1038/S41380-019-0488-Z |
0.302 |
|
| 2019 |
Kolosowska N, Keuters MH, Wojciechowski S, Keksa-Goldsteine V, Laine M, Malm T, Goldsteins G, Koistinaho J, Dhungana H. Peripheral Administration of IL-13 Induces Anti-inflammatory Microglial/Macrophage Responses and Provides Neuroprotection in Ischemic Stroke. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 31372938 DOI: 10.1007/S13311-019-00761-0 |
0.355 |
|
| 2019 |
Singh Y, Leinonen H, Fazaludeen F, Jaronen M, Guest D, Buckley N, Byts N, Oksa P, Jalkanen K, Iqbal I, Huuskonen M, Savchenko E, Keksa-Goldsteine V, Chew S, Myllyharju J, ... ... Koistinaho J, et al. Loss of Cln5 leads to altered Gad1 expression and deficits in interneuron development in mice. Human Molecular Genetics. PMID 31294445 DOI: 10.1093/Hmg/Ddz165 |
0.368 |
|
| 2019 |
Lehtonen Š, Sonninen TM, Wojciechowski S, Goldsteins G, Koistinaho J. Dysfunction of Cellular Proteostasis in Parkinson's Disease. Frontiers in Neuroscience. 13: 457. PMID 31133790 DOI: 10.3389/Fnins.2019.00457 |
0.309 |
|
| 2019 |
Oksanen M, Lehtonen S, Jaronen M, Goldsteins G, Hämäläinen RH, Koistinaho J. Astrocyte alterations in neurodegenerative pathologies and their modeling in human induced pluripotent stem cell platforms. Cellular and Molecular Life Sciences : Cmls. PMID 31016348 DOI: 10.1007/S00018-019-03111-7 |
0.371 |
|
| 2019 |
Korhonen P, Pollari E, Kanninen KM, Savchenko E, Lehtonen Š, Wojciechowski S, Pomeshchik Y, Van Den Bosch L, Goldsteins G, Koistinaho J, Malm T. Long-term interleukin-33 treatment delays disease onset and alleviates astrocytic activation in a transgenic mouse model of amyotrophic lateral sclerosis. Ibro Reports. 6: 74-86. PMID 30705990 DOI: 10.1016/J.Ibror.2019.01.005 |
0.73 |
|
| 2018 |
Gynther M, Puris E, Peltokangas S, Auriola S, Kanninen KM, Koistinaho J, Huttunen KM, Ruponen M, Vellonen KS. Alzheimer's Disease Phenotype or Inflammatory Insult Does Not Alter Function of L-Type Amino Acid Transporter 1 in Mouse Blood-Brain Barrier and Primary Astrocytes. Pharmaceutical Research. 36: 17. PMID 30488131 DOI: 10.1007/S11095-018-2546-7 |
0.312 |
|
| 2018 |
Konttinen H, Gureviciene I, Oksanen M, Grubman A, Loppi S, Huuskonen MT, Korhonen P, Lampinen R, Keuters M, Belaya I, Tanila H, Kanninen KM, Goldsteins G, Landreth G, Koistinaho J, et al. PPARβ/δ-agonist GW0742 ameliorates dysfunction in fatty acid oxidation in PSEN1ΔE9 astrocytes. Glia. PMID 30453390 DOI: 10.1002/Glia.23534 |
0.359 |
|
| 2018 |
Choo XY, Liddell JR, Huuskonen MT, Grubman A, Moujalled D, Roberts J, Kysenius K, Patten L, Quek H, Oikari LE, Duncan C, James SA, McInnes LE, Hayne DJ, Donnelly PS, ... ... Koistinaho J, et al. Cu(atsm) Attenuates Neuroinflammation. Frontiers in Neuroscience. 12: 668. PMID 30319344 DOI: 10.3389/Fnins.2018.00668 |
0.324 |
|
| 2018 |
Oksanen M, Hyötyläinen I, Voutilainen J, Puttonen KA, Hämäläinen RH, Graff C, Lehtonen Š, Koistinaho J. Generation of a human induced pluripotent stem cell line (LL008 1.4) from a familial Alzheimer's disease patient carrying a double KM670/671NL (Swedish) mutation in APP gene. Stem Cell Research. 31: 181-185. PMID 30099334 DOI: 10.1016/J.Scr.2018.07.024 |
0.315 |
|
| 2018 |
Loppi S, Kolosowska N, Kärkkäinen O, Korhonen P, Huuskonen M, Grubman A, Dhungana H, Wojciechowski S, Pomeshchik Y, Giordano M, Kagechika H, White A, Auriola S, Koistinaho J, Landreth G, et al. HX600, a synthetic agonist for RXR-Nurr1 heterodimer complex, prevents ischemia-induced neuronal damage. Brain, Behavior, and Immunity. PMID 30063972 DOI: 10.1016/J.Bbi.2018.07.021 |
0.738 |
|
| 2018 |
Lehtonen Š, Höytyläinen I, Voutilainen J, Sonninen TM, Kuusisto J, Laakso M, Hämäläinen RH, Oksanen M, Koistinaho J. Generation of a human induced pluripotent stem cell line from a patient with a rare A673T variant in amyloid precursor protein gene that reduces the risk for Alzheimer's disease. Stem Cell Research. 30: 96-99. PMID 29807259 DOI: 10.1016/J.Scr.2018.05.014 |
0.32 |
|
| 2018 |
Belt H, Koponen JK, Kekarainen T, Puttonen KA, Mäkinen PI, Niskanen H, Oja J, Wirth G, Koistinaho J, Kaikkonen MU, Ylä-Herttuala S. Temporal Dynamics of Gene Expression During Endothelial Cell Differentiation From Human iPS Cells: A Comparison Study of Signalling Factors and Small Molecules. Frontiers in Cardiovascular Medicine. 5: 16. PMID 29594149 DOI: 10.3389/Fcvm.2018.00016 |
0.318 |
|
| 2018 |
Pinto S, Ferreira S, Moreira F, Ribeiro A, Cunha C, Vaz AR, Oksanen M, Petersen AJ, Puttonen K, Zhang S, Hämäläinen RH, Koistinaho J, Fernandes A, Brites D. Human iPSC-derived neurons and astrocytes as models of neurodegeneration, neuroinflammation and vesicular trafficking in Alzheimer's disease Free Radical Biology and Medicine. 120: S158. DOI: 10.1016/J.Freeradbiomed.2018.04.521 |
0.381 |
|
| 2017 |
Oksanen M, Petersen AJ, Naumenko N, Puttonen K, Lehtonen Š, Gubert Olivé M, Shakirzyanova A, Leskelä S, Sarajärvi T, Viitanen M, Rinne JO, Hiltunen M, Haapasalo A, Giniatullin R, Tavi P, ... ... Koistinaho J, et al. PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease. Stem Cell Reports. PMID 29153989 DOI: 10.1016/J.Stemcr.2017.10.016 |
0.383 |
|
| 2017 |
Martiskainen H, Paldanius KMA, Natunen T, Takalo M, Marttinen M, Leskelä S, Huber N, Mäkinen P, Bertling E, Dhungana H, Huuskonen M, Honkakoski P, Hotulainen P, Rilla K, Koistinaho J, et al. DHCR24 exerts neuroprotection upon inflammation-induced neuronal death. Journal of Neuroinflammation. 14: 215. PMID 29115990 DOI: 10.1186/S12974-017-0991-6 |
0.373 |
|
| 2017 |
Vellonen KS, Ihalainen J, Boucau MC, Gosselet F, Picardat T, Gynther M, Kanninen KM, White AR, Malm T, Koistinaho J, Forsberg MM, Ruponen M. Disease-Induced Alterations in Brain Drug Transporters in Animal Models of Alzheimer's Disease. Pharmaceutical Research. PMID 28952054 DOI: 10.1007/S11095-017-2263-7 |
0.311 |
|
| 2017 |
Savchenko E, Singh Y, Konttinen H, Lejavova K, Mediavilla Santos L, Grubman A, Kärkkäinen V, Keksa-Goldsteine V, Naumenko N, Tavi P, White AR, Malm TM, Koistinaho J, Kanninen KM. Loss of CLN5 causes altered neurogenesis in a childhood neurodegenerative disorder. Disease Models & Mechanisms. PMID 28733362 DOI: 10.1242/Dmm.029165 |
0.385 |
|
| 2017 |
Leinonen H, Keksa-Goldsteine V, Ragauskas S, Kohlmann P, Singh Y, Savchenko E, Puranen J, Malm T, Kalesnykas G, Koistinaho J, Tanila H, Kanninen KM. Retinal Degeneration In A Mouse Model Of CLN5 Disease Is Associated With Compromised Autophagy. Scientific Reports. 7: 1597. PMID 28487519 DOI: 10.1038/S41598-017-01716-1 |
0.316 |
|
| 2017 |
Lemarchant S, Wojciechowski S, Vivien D, Koistinaho J. ADAMTS-4 in central nervous system pathologies. Journal of Neuroscience Research. PMID 28084617 DOI: 10.1002/Jnr.24021 |
0.356 |
|
| 2017 |
Huuskonen MT, Tuo QZ, Loppi S, Dhungana H, Korhonen P, McInnes LE, Donnelly PS, Grubman A, Wojciechowski S, Lejavova K, Pomeshchik Y, Periviita L, Kosonen L, Giordano M, Walker FR, ... ... Koistinaho J, et al. The Copper bis(thiosemicarbazone) Complex Cu(II)(atsm) Is Protective Against Cerebral Ischemia Through Modulation of the Inflammatory Milieu. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 28050710 DOI: 10.1007/S13311-016-0504-9 |
0.723 |
|
| 2017 |
Achuta VS, Grym H, Putkonen N, Louhivuori V, Kärkkäinen V, Koistinaho J, Roybon L, Castrén ML. Cover Image Developmental Neurobiology. 77: i-i. DOI: 10.1002/Dneu.22494 |
0.575 |
|
| 2016 |
Holmqvist S, Lehtonen Š, Chumarina M, Puttonen KA, Azevedo C, Lebedeva O, Ruponen M, Oksanen M, Djelloul M, Collin A, Goldwurm S, Meyer M, Lagarkova M, Kiselev S, Koistinaho J, et al. Creation of a library of induced pluripotent stem cells from Parkinsonian patients. Npj Parkinson's Disease. 2: 16009. PMID 28725696 DOI: 10.1038/Npjparkd.2016.9 |
0.663 |
|
| 2016 |
Savchenko E, Malm T, Konttinen H, Hämäläinen RH, Guerrero-Toro C, Wojciechowski S, Giniatullin R, Koistinaho J, Magga J. Aβ and Inflammatory Stimulus Activate Diverse Signaling Pathways in Monocytic Cells: Implications in Retaining Phagocytosis in Aβ-Laden Environment. Frontiers in Cellular Neuroscience. 10: 279. PMID 27994540 DOI: 10.3389/Fncel.2016.00279 |
0.34 |
|
| 2016 |
Huuskonen MT, Loppi S, Dhungana H, Keksa-Goldsteine V, Lemarchant S, Korhonen P, Wojciechowski S, Pollari E, Valonen P, Koponen J, Takashima A, Landreth G, Goldsteins G, Malm T, Koistinaho J, et al. Bexarotene targets autophagy and is protective against thromboembolic stroke in aged mice with tauopathy. Scientific Reports. 6: 33176. PMID 27624652 DOI: 10.1038/Srep33176 |
0.367 |
|
| 2016 |
Rolova T, Dhungana H, Korhonen P, Valonen P, Kolosowska N, Konttinen H, Kanninen K, Tanila H, Malm T, Koistinaho J. Deletion of Nuclear Factor kappa B p50 Subunit Decreases Inflammatory Response and Mildly Protects Neurons from Transient Forebrain Ischemia-induced Damage. Aging and Disease. 7: 450-65. PMID 27493832 DOI: 10.14336/Ad.2015.1123 |
0.366 |
|
| 2016 |
Achuta VS, Grym H, Putkonen N, Louhivuori V, Kärkkäinen V, Koistinaho J, Roybon L, Castrén ML. Metabotropic glutamate receptor 5 responses dictate differentiation of neural progenitors to NMDA-responsive cells in fragile X syndrome. Developmental Neurobiology. PMID 27411166 DOI: 10.1002/Dneu.22419 |
0.649 |
|
| 2016 |
Lemarchant S, Dunghana H, Pomeshchik Y, Leinonen H, Kolosowska N, Korhonen P, Kanninen KM, García-Berrocoso T, Montaner J, Malm T, Koistinaho J. Anti-inflammatory effects of ADAMTS-4 in a mouse model of ischemic stroke. Glia. 64: 1492-507. PMID 27301579 DOI: 10.1002/Glia.23017 |
0.737 |
|
| 2016 |
Lemarchant S, Pomeshchik Y, Kidin I, Kärkkäinen V, Valonen P, Lehtonen S, Goldsteins G, Malm T, Kanninen K, Koistinaho J. Erratum to: ADAMTS-4 promotes neurodegeneration in a mouse model of amyotrophic lateral sclerosis. Molecular Neurodegeneration. 11: 15. PMID 26858022 DOI: 10.1186/S13024-016-0080-9 |
0.698 |
|
| 2016 |
Lemarchant S, Pomeshchik Y, Kidin I, Kärkkäinen V, Valonen P, Lehtonen S, Goldsteins G, Malm T, Kanninen K, Koistinaho J. ADAMTS-4 promotes neurodegeneration in a mouse model of amyotrophic lateral sclerosis. Molecular Neurodegeneration. 11: 10. PMID 26809777 DOI: 10.1186/S13024-016-0078-3 |
0.722 |
|
| 2016 |
Kanninen KM, Bister N, Koistinaho J, Malm T. Exosomes as new diagnostic tools in CNS diseases. Biochimica Et Biophysica Acta. 1862: 403-10. PMID 26432482 DOI: 10.1016/J.Bbadis.2015.09.020 |
0.33 |
|
| 2015 |
Puttonen KA, Ruponen M, Naumenko N, Hovatta OH, Tavi P, Koistinaho J. Generation of Functional Neuromuscular Junctions from Human Pluripotent Stem Cell Lines. Frontiers in Cellular Neuroscience. 9: 473. PMID 26696831 DOI: 10.3389/Fncel.2015.00473 |
0.348 |
|
| 2015 |
Kanninen KM, Pomeshchik Y, Leinonen H, Malm T, Koistinaho J, Levonen AL. Applications of the Keap1-Nrf2 system for gene and cell therapy. Free Radical Biology & Medicine. 88: 350-61. PMID 26164630 DOI: 10.1016/J.Freeradbiomed.2015.06.037 |
0.72 |
|
| 2015 |
Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T, Vitorica J, Ransohoff RM, Herrup K, Frautschy SA, Finsen B, Brown GC, Verkhratsky A, ... ... Koistinaho J, et al. Neuroinflammation in Alzheimer's disease. The Lancet. Neurology. 14: 388-405. PMID 25792098 DOI: 10.1016/S1474-4422(15)70016-5 |
0.353 |
|
| 2015 |
Pomeshchik Y, Puttonen KA, Kidin I, Ruponen M, Lehtonen S, Malm T, Åkesson E, Hovatta O, Koistinaho J. Transplanted Human Induced Pluripotent Stem Cell-Derived Neural Progenitor Cells Do Not Promote Functional Recovery of Pharmacologically Immunosuppressed Mice With Contusion Spinal Cord Injury. Cell Transplantation. 24: 1799-812. PMID 25203632 DOI: 10.3727/096368914X684079 |
0.713 |
|
| 2015 |
Pomeshchik Y, Kidin I, Korhonen P, Savchenko E, Jaronen M, Lehtonen S, Wojciechowski S, Kanninen K, Koistinaho J, Malm T. Interleukin-33 treatment reduces secondary injury and improves functional recovery after contusion spinal cord injury. Brain, Behavior, and Immunity. 44: 68-81. PMID 25153903 DOI: 10.1016/J.Bbi.2014.08.002 |
0.713 |
|
| 2014 |
Kemppainen S, Hämäläinen E, Miettinen PO, Koistinaho J, Tanila H. Behavioral and neuropathological consequences of transient global ischemia in APP/PS1 Alzheimer model mice. Behavioural Brain Research. 275: 15-26. PMID 25192639 DOI: 10.1016/J.Bbr.2014.08.050 |
0.36 |
|
| 2014 |
Vehviläinen P, Koistinaho J, Gundars G. Mechanisms of mutant SOD1 induced mitochondrial toxicity in amyotrophic lateral sclerosis. Frontiers in Cellular Neuroscience. 8: 126. PMID 24847211 DOI: 10.3389/Fncel.2014.00126 |
0.301 |
|
| 2014 |
Grubman A, Pollari E, Duncan C, Caragounis A, Blom T, Volitakis I, Wong A, Cooper J, Crouch PJ, Koistinaho J, Jalanko A, White AR, Kanninen KM. Deregulation of biometal homeostasis: the missing link for neuronal ceroid lipofuscinoses? Metallomics : Integrated Biometal Science. 6: 932-43. PMID 24804307 DOI: 10.1039/C4Mt00032C |
0.368 |
|
| 2014 |
Kärkkäinen V, Pomeshchik Y, Savchenko E, Dhungana H, Kurronen A, Lehtonen S, Naumenko N, Tavi P, Levonen AL, Yamamoto M, Malm T, Magga J, Kanninen KM, Koistinaho J. Nrf2 regulates neurogenesis and protects neural progenitor cells against Aβ toxicity. Stem Cells (Dayton, Ohio). 32: 1904-16. PMID 24753106 DOI: 10.1002/Stem.1666 |
0.749 |
|
| 2014 |
Heikkinen R, Malm T, Heikkilä J, Muona A, Tanila H, Koistinaho M, Koistinaho J. Susceptibility to focal and global brain ischemia of Alzheimer mice displaying aβ deposits: effect of immunoglobulin. Aging and Disease. 5: 76-87. PMID 24729933 DOI: 10.14336/Ad.2014.050076 |
0.372 |
|
| 2014 |
Grubman A, Lidgerwood GE, Duncan C, Bica L, Tan JL, Parker SJ, Caragounis A, Meyerowitz J, Volitakis I, Moujalled D, Liddell JR, Hickey JL, Horne M, Longmuir S, Koistinaho J, et al. Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder. Acta Neuropathologica Communications. 2: 25. PMID 24581221 DOI: 10.1186/2051-5960-2-25 |
0.319 |
|
| 2014 |
Lemarchant S, Pruvost M, Hébert M, Gauberti M, Hommet Y, Briens A, Maubert E, Gueye Y, Féron F, Petite D, Mersel M, do Rego JC, Vaudry H, Koistinaho J, Ali C, et al. tPA promotes ADAMTS-4-induced CSPG degradation, thereby enhancing neuroplasticity following spinal cord injury. Neurobiology of Disease. 66: 28-42. PMID 24576594 DOI: 10.1016/J.Nbd.2014.02.005 |
0.331 |
|
| 2014 |
Rolova T, Puli L, Magga J, Dhungana H, Kanninen K, Wojciehowski S, Salminen A, Tanila H, Koistinaho J, Malm T. Complex regulation of acute and chronic neuroinflammatory responses in mouse models deficient for nuclear factor kappa B p50 subunit. Neurobiology of Disease. 64: 16-29. PMID 24345324 DOI: 10.1016/J.Nbd.2013.12.003 |
0.341 |
|
| 2014 |
Pomeshchik Y, Kidin I, Savchenko E, Rolova T, Yamamoto M, Levonen AL, Ylä-Herttuala S, Malm T, Kanninen K, Koistinaho J. Does Nrf2 gene transfer facilitate recovery after contusion spinal cord injury? Antioxidants & Redox Signaling. 20: 1313-23. PMID 23841575 DOI: 10.1089/ars.2013.5453 |
0.722 |
|
| 2013 |
Lemarchant S, Pruvost M, Montaner J, Emery E, Vivien D, Kanninen K, Koistinaho J. ADAMTS proteoglycanases in the physiological and pathological central nervous system. Journal of Neuroinflammation. 10: 133. PMID 24176075 DOI: 10.1186/1742-2094-10-133 |
0.331 |
|
| 2013 |
Dhungana H, Rolova T, Savchenko E, Wojciechowski S, Savolainen K, Ruotsalainen AK, Sullivan PM, Koistinaho J, Malm T. Western-type diet modulates inflammatory responses and impairs functional outcome following permanent middle cerebral artery occlusion in aged mice expressing the human apolipoprotein E4 allele Journal of Neuroinflammation. 10. PMID 23957944 DOI: 10.1186/1742-2094-10-102 |
0.332 |
|
| 2013 |
Dhungana H, Malm T, Denes A, Valonen P, Wojciechowski S, Magga J, Savchenko E, Humphreys N, Grencis R, Rothwell N, Koistinaho J. Aging aggravates ischemic stroke-induced brain damage in mice with chronic peripheral infection. Aging Cell. 12: 842-50. PMID 23725345 DOI: 10.1111/Acel.12106 |
0.306 |
|
| 2013 |
Parker SJ, Koistinaho J, White AR, Kanninen KM. Biometals in rare neurodegenerative disorders of childhood. Frontiers in Aging Neuroscience. 5: 14. PMID 23531702 DOI: 10.3389/Fnagi.2013.00014 |
0.303 |
|
| 2013 |
Puttonen KA, Ruponen M, Kauppinen R, Wojciechowski S, Hovatta O, Koistinaho J. Improved method of producing human neural progenitor cells of high purity and in large quantities from pluripotent stem cells for transplantation studies. Cell Transplantation. 22: 1753-66. PMID 23127329 DOI: 10.3727/096368912X658764 |
0.312 |
|
| 2013 |
Jaronen M, Vehviläinen P, Malm T, Keksa-Goldsteine V, Pollari E, Valonen P, Koistinaho J, Goldsteins G. Protein disulfide isomerase in ALS mouse glia links protein misfolding with NADPH oxidase-catalyzed superoxide production. Human Molecular Genetics. 22: 646-55. PMID 23118353 DOI: 10.1093/Hmg/Dds472 |
0.396 |
|
| 2012 |
Malm T, Magga J, Koistinaho J. Animal Models of Alzheimer's Disease: Utilization of Transgenic Alzheimer's Disease Models in Studies of Amyloid Beta Clearance. Current Translational Geriatrics and Experimental Gerontology Reports. 1: 11-20. PMID 23440676 DOI: 10.1007/S13670-011-0004-Z |
0.357 |
|
| 2012 |
Karkkainen V, Magga J, Koistinaho J, Malm T. Brain environment and Alzheimer's disease mutations affect the survival, migration and differentiation of neural progenitor cells. Current Alzheimer Research. 9: 1030-42. PMID 22950909 DOI: 10.2174/156720512803569028 |
0.367 |
|
| 2012 |
Puli L, Pomeshchik Y, Olas K, Malm T, Koistinaho J, Tanila H. Effects of human intravenous immunoglobulin on amyloid pathology and neuroinflammation in a mouse model of Alzheimer's disease. Journal of Neuroinflammation. 9: 105. PMID 22642812 DOI: 10.1186/1742-2094-9-105 |
0.718 |
|
| 2012 |
Magga J, Savchenko E, Malm T, Rolova T, Pollari E, Valonen P, Lehtonen Š, Jantunen E, Aarnio J, Lehenkari P, Koistinaho M, Muona A, Koistinaho J. Production of monocytic cells from bone marrow stem cells: therapeutic usage in Alzheimer's disease. Journal of Cellular and Molecular Medicine. 16: 1060-73. PMID 21777378 DOI: 10.1111/J.1582-4934.2011.01390.X |
0.356 |
|
| 2012 |
Kurronen A, Pihlaja R, Pollari E, Kanninen K, Storvik M, Wong G, Koistinaho M, Koistinaho J. Adult and neonatal astrocytes exhibit diverse gene expression profiles in response to beta amyloid <i>ex vivo</i> World Journal of Neuroscience. 2: 57-67. DOI: 10.4236/Wjns.2012.22009 |
0.361 |
|
| 2011 |
Malm T, Koistinaho J, Kanninen K. Utilization of APPswe/PS1dE9 Transgenic Mice in Research of Alzheimer's Disease: Focus on Gene Therapy and Cell-Based Therapy Applications. International Journal of Alzheimer's Disease. 2011: 517160. PMID 22114743 DOI: 10.4061/2011/517160 |
0.37 |
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| 2011 |
Pihlaja R, Koistinaho J, Kauppinen R, Sandholm J, Tanila H, Koistinaho M. Multiple cellular and molecular mechanisms are involved in human Aβ clearance by transplanted adult astrocytes. Glia. 59: 1643-57. PMID 21826742 DOI: 10.1002/Glia.21212 |
0.323 |
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| 2011 |
Pollari E, Savchenko E, Jaronen M, Kanninen K, Malm T, Wojciechowski S, Ahtoniemi T, Goldsteins G, Giniatullina R, Giniatullin R, Koistinaho J, Magga J. Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis. Journal of Neuroinflammation. 8: 74. PMID 21711557 DOI: 10.1186/1742-2094-8-74 |
0.32 |
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| 2011 |
Koistinaho J, Malm T, Goldsteins G. Glycogen synthase kinase-3β: a mediator of inflammation in Alzheimer's disease? International Journal of Alzheimer's Disease. 2011: 129753. PMID 21629736 DOI: 10.4061/2011/129753 |
0.366 |
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| 2011 |
Kanninen K, White AR, Koistinaho J, Malm T. Targeting Glycogen Synthase Kinase-3β for Therapeutic Benefit against Oxidative Stress in Alzheimer's Disease: Involvement of the Nrf2-ARE Pathway. International Journal of Alzheimer's Disease. 2011: 985085. PMID 21629716 DOI: 10.4061/2011/985085 |
0.326 |
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| 2011 |
Savchenko E, Magga J, Tarja M, Valonen P, Muona A, Koistinaho M, Koistinaho J. P3-465: Hematopoietic stem cell-derived monocytic cells are capable of clearing amyloid-beta in Alzheimer's disease mouse model Alzheimer's & Dementia. 7: S664-S664. DOI: 10.1016/J.Jalz.2011.05.1909 |
0.318 |
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| 2010 |
Magga J, Puli L, Pihlaja R, Kanninen K, Neulamaa S, Malm T, Härtig W, Grosche J, Goldsteins G, Tanila H, Koistinaho J, Koistinaho M. Human intravenous immunoglobulin provides protection against Aβ toxicity by multiple mechanisms in a mouse model of Alzheimer's disease. Journal of Neuroinflammation. 7: 90. PMID 21138577 DOI: 10.1186/1742-2094-7-90 |
0.333 |
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| 2010 |
Malm T, Koistinaho M, Muona A, Magga J, Koistinaho J. The role and therapeutic potential of monocytic cells in Alzheimer's disease. Glia. 58: 889-900. PMID 20155817 DOI: 10.1002/Glia.20973 |
0.352 |
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| 2009 |
Kanninen K, Heikkinen R, Malm T, Rolova T, Kuhmonen S, Leinonen H, Ylä-Herttuala S, Tanila H, Levonen AL, Koistinaho M, Koistinaho J. Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 106: 16505-10. PMID 19805328 DOI: 10.1073/Pnas.0908397106 |
0.376 |
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| 2009 |
Heikkinen R, Malm T, Boman S, Kuhmonen S, Ahtoniemi T, Muona A, Tanila H, Koistinaho J, Koistinaho M. A low-dose of intravenous immunoglobulin provides protection in focal and global brain ischemia models and abolishes the increased ischemic vulnerability of aged APP/PS1 mice Alzheimers & Dementia. 5: 478. DOI: 10.1016/J.Jalz.2009.04.725 |
0.311 |
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| 2008 |
Kanninen K, Malm TM, Jyrkkänen HK, Goldsteins G, Keksa-Goldsteine V, Tanila H, Yamamoto M, Ylä-Herttuala S, Levonen AL, Koistinaho J. Nuclear factor erythroid 2-related factor 2 protects against beta amyloid. Molecular and Cellular Neurosciences. 39: 302-13. PMID 18706502 DOI: 10.1016/J.Mcn.2008.07.010 |
0.349 |
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| 2008 |
Malm TM, Magga J, Kuh GF, Vatanen T, Koistinaho M, Koistinaho J. Minocycline reduces engraftment and activation of bone marrow-derived cells but sustains their phagocytic activity in a mouse model of Alzheimer's disease. Glia. 56: 1767-79. PMID 18649403 DOI: 10.1002/Glia.20726 |
0.355 |
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| 2008 |
Jyrkkänen HK, Kansanen E, Inkala M, Kivelä AM, Hurttila H, Heinonen SE, Goldsteins G, Jauhiainen S, Tiainen S, Makkonen H, Oskolkova O, Afonyushkin T, Koistinaho J, Yamamoto M, Bochkov VN, et al. Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo. Circulation Research. 103: e1-9. PMID 18535259 DOI: 10.1161/Circresaha.108.176883 |
0.326 |
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| 2008 |
Endres M, Engelhardt B, Koistinaho J, Lindvall O, Meairs S, Mohr JP, Planas A, Rothwell N, Schwaninger M, Schwab ME, Vivien D, Wieloch T, Dirnagl U. Improving outcome after stroke: overcoming the translational roadblock. Cerebrovascular Diseases (Basel, Switzerland). 25: 268-78. PMID 18292653 DOI: 10.1159/000118039 |
0.312 |
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| 2008 |
Pihlaja R, Koistinaho J, Malm T, Sikkilä H, Vainio S, Koistinaho M. Transplanted astrocytes internalize deposited beta-amyloid peptides in a transgenic mouse model of Alzheimer's disease. Glia. 56: 154-63. PMID 18004725 DOI: 10.1002/Glia.20599 |
0.333 |
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| 2007 |
Malm TM, Iivonen H, Goldsteins G, Keksa-Goldsteine V, Ahtoniemi T, Kanninen K, Salminen A, Auriola S, Van Groen T, Tanila H, Koistinaho J. Pyrrolidine dithiocarbamate activates Akt and improves spatial learning in APP/PS1 mice without affecting beta-amyloid burden. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3712-21. PMID 17409235 DOI: 10.1523/Jneurosci.0059-07.2007 |
0.357 |
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| 2007 |
Ahtoniemi T, Goldsteins G, Keksa-Goldsteine V, Malm T, Kanninen K, Salminen A, Koistinaho J. Pyrrolidine dithiocarbamate inhibits induction of immunoproteasome and decreases survival in a rat model of amyotrophic lateral sclerosis. Molecular Pharmacology. 71: 30-7. PMID 17008387 DOI: 10.1124/Mol.106.028415 |
0.352 |
|
| 2006 |
Malm T, Ort M, Tähtivaara L, Jukarainen N, Goldsteins G, Puoliväli J, Nurmi A, Pussinen R, Ahtoniemi T, Miettinen TK, Kanninen K, Leskinen S, Vartiainen N, Yrjänheikki J, Laatikainen R, ... ... Koistinaho J, et al. beta-Amyloid infusion results in delayed and age-dependent learning deficits without role of inflammation or beta-amyloid deposits. Proceedings of the National Academy of Sciences of the United States of America. 103: 8852-7. PMID 16723396 DOI: 10.1073/Pnas.0602896103 |
0.307 |
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| 2006 |
Nurmi A, Goldsteins G, Närväinen J, Pihlaja R, Ahtoniemi T, Gröhn O, Koistinaho J. Antioxidant pyrrolidine dithiocarbamate activates Akt-GSK signaling and is neuroprotective in neonatal hypoxia-ischemia. Free Radical Biology & Medicine. 40: 1776-84. PMID 16678015 DOI: 10.1016/J.Freeradbiomed.2006.01.011 |
0.367 |
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| 2006 |
Korolainen MA, Goldsteins G, Nyman TA, Alafuzoff I, Koistinaho J, Pirttilä T. Oxidative modification of proteins in the frontal cortex of Alzheimer's disease brain. Neurobiology of Aging. 27: 42-53. PMID 16298240 DOI: 10.1016/J.Neurobiolaging.2004.11.010 |
0.303 |
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| 2005 |
Koistinaho M, Koistinaho J. Interactions between Alzheimer's disease and cerebral ischemia--focus on inflammation. Brain Research. Brain Research Reviews. 48: 240-50. PMID 15850663 DOI: 10.1016/J.Brainresrev.2004.12.014 |
0.391 |
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| 2005 |
Malm TM, Koistinaho M, Pärepalo M, Vatanen T, Ooka A, Karlsson S, Koistinaho J. Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice. Neurobiology of Disease. 18: 134-42. PMID 15649704 DOI: 10.1016/J.Nbd.2004.09.009 |
0.342 |
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| 2004 |
Nurmi A, Vartiainen N, Pihlaja R, Goldsteins G, Yrjänheikki J, Koistinaho J. Pyrrolidine dithiocarbamate inhibits translocation of nuclear factor kappa-B in neurons and protects against brain ischaemia with a wide therapeutic time window. Journal of Neurochemistry. 91: 755-65. PMID 15485504 DOI: 10.1111/J.1471-4159.2004.02756.X |
0.337 |
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| 2004 |
Hanisch UK, van Rossum D, Xie Y, Gast K, Misselwitz R, Auriola S, Goldsteins G, Koistinaho J, Kettenmann H, Möller T. The microglia-activating potential of thrombin: the protease is not involved in the induction of proinflammatory cytokines and chemokines. The Journal of Biological Chemistry. 279: 51880-7. PMID 15452111 DOI: 10.1074/Jbc.M408318200 |
0.318 |
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| 2003 |
Koponen S, Kurkinen K, Akerman KE, Mochly-Rosen D, Chan PH, Koistinaho J. Prevention of NMDA-induced death of cortical neurons by inhibition of protein kinase Czeta. Journal of Neurochemistry. 86: 442-50. PMID 12871585 DOI: 10.1046/J.1471-4159.2003.01846.X |
0.351 |
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| 2003 |
Vartiainen N, Goldsteins G, Keksa-Goldsteine V, Chan PH, Koistinaho J. Aspirin inhibits p44/42 mitogen-activated protein kinase and is protective against hypoxia/reoxygenation neuronal damage. Stroke; a Journal of Cerebral Circulation. 34: 752-7. PMID 12624303 DOI: 10.1161/01.Str.0000057813.31798.1F |
0.347 |
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| 2002 |
Koistinaho M, Koistinaho J. Role of p38 and p44/42 mitogen-activated protein kinases in microglia. Glia. 40: 175-83. PMID 12379905 DOI: 10.1002/Glia.10151 |
0.327 |
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| 2002 |
Vartiainen N, Keksa-Goldsteine V, Goldsteins G, Koistinaho J. Aspirin provides cyclin-dependent kinase 5-dependent protection against subsequent hypoxia/reoxygenation damage in culture. Journal of Neurochemistry. 82: 329-35. PMID 12124433 DOI: 10.1046/J.1471-4159.2002.00959.X |
0.364 |
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| 2002 |
Koistinaho M, Kettunen MI, Holtzman DM, Kauppinen RA, Higgins LS, Koistinaho J. Expression of human apolipoprotein E downregulates amyloid precursor protein-induced ischemic susceptibility. Stroke; a Journal of Cerebral Circulation. 33: 1905-10. PMID 12105373 DOI: 10.1161/01.Str.0000020124.61998.Bc |
0.341 |
|
| 2002 |
Kaasinen SK, Goldsteins G, Alhonen L, Jänne J, Koistinaho J. Induction and activation of protein kinase C delta in hippocampus and cortex after kainic acid treatment. Experimental Neurology. 176: 203-12. PMID 12093097 DOI: 10.1006/Exnr.2002.7919 |
0.329 |
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| 2002 |
Tikka TM, Vartiainen NE, Goldsteins G, Oja SS, Andersen PM, Marklund SL, Koistinaho J. Minocycline prevents neurotoxicity induced by cerebrospinal fluid from patients with motor neurone disease. Brain : a Journal of Neurology. 125: 722-31. PMID 11912107 DOI: 10.1093/Brain/Awf068 |
0.355 |
|
| 2002 |
Koistinaho M, Kettunen MI, Goldsteins G, Keinänen R, Salminen A, Ort M, Bures J, Liu D, Kauppinen RA, Higgins LS, Koistinaho J. Beta-amyloid precursor protein transgenic mice that harbor diffuse A beta deposits but do not form plaques show increased ischemic vulnerability: role of inflammation. Proceedings of the National Academy of Sciences of the United States of America. 99: 1610-5. PMID 11818564 DOI: 10.1073/Pnas.032670899 |
0.396 |
|
| 2002 |
Vartiainen N, Huang CY, Salminen A, Goldsteins G, Chan PH, Koistinaho J. Piroxicam and NS-398 rescue neurones from hypoxia/reoxygenation damage by a mechanism independent of cyclo-oxygenase inhibition. Journal of Neurochemistry. 76: 480-9. PMID 11208911 DOI: 10.1046/J.1471-4159.2001.00065.X |
0.353 |
|
| 2001 |
Koistinaho M, Ort M, Cimadevilla JM, Vondrous R, Cordell B, Koistinaho J, Bures J, Higgins LS. Specific spatial learning deficits become severe with age in beta -amyloid precursor protein transgenic mice that harbor diffuse beta -amyloid deposits but do not form plaques. Proceedings of the National Academy of Sciences of the United States of America. 98: 14675-80. PMID 11724968 DOI: 10.1073/Pnas.261562998 |
0.317 |
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| 2001 |
Tikka T, Usenius T, Tenhunen M, Keinänen R, Koistinaho J. Tetracycline derivatives and ceftriaxone, a cephalosporin antibiotic, protect neurons against apoptosis induced by ionizing radiation. Journal of Neurochemistry. 78: 1409-14. PMID 11579149 DOI: 10.1046/J.1471-4159.2001.00543.X |
0.359 |
|
| 2001 |
Chen Y, Vartiainen NE, Ying W, Chan PH, Koistinaho J, Swanson RA. Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism. Journal of Neurochemistry. 77: 1601-10. PMID 11413243 DOI: 10.1046/J.1471-4159.2001.00374.X |
0.337 |
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| 2001 |
Tikka T, Fiebich BL, Goldsteins G, Keinänen R, Koistinaho J. Minocycline, a Tetracycline Derivative, Is Neuroprotective against Excitotoxicity by Inhibiting Activation and Proliferation of Microglia The Journal of Neuroscience. 21: 2580-2588. DOI: 10.1523/Jneurosci.21-08-02580.2001 |
0.344 |
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| 2000 |
Yrjänheikki J, Koistinaho J, Copin JC, de Crespigny A, Moseley ME, Chan PH. Spreading depression-induced expression of c-fos and cyclooxygenase-2 in transgenic mice that overexpress human copper/zinc-superoxide dismutase. Journal of Neurotrauma. 17: 713-8. PMID 10972246 DOI: 10.1089/089771500415445 |
0.32 |
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| 2000 |
Saarelainen T, Lukkarinen JA, Koponen S, Gröhn OH, Jolkkonen J, Koponen E, Haapasalo A, Alhonen L, Wong G, Koistinaho J, Kauppinen RA, Castrén E. Transgenic mice overexpressing truncated trkB neurotrophin receptors in neurons show increased susceptibility to cortical injury after focal cerebral ischemia. Molecular and Cellular Neurosciences. 16: 87-96. PMID 10924253 DOI: 10.1006/Mcne.2000.0863 |
0.361 |
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| 2000 |
Koistinaho J, Chan PH. Spreading depression-induced cyclooxygenase-2 expression in the cortex. Neurochemical Research. 25: 645-51. PMID 10905626 DOI: 10.1023/A:1007559003261 |
0.349 |
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| 2000 |
Kaasinen K, Koistinaho J, Alhonen L, Jänne J. Overexpression of spermidine/spermine N-acetyltransferase in transgenic mice protects the animals from kainate-induced toxicity. The European Journal of Neuroscience. 12: 540-8. PMID 10712633 DOI: 10.1046/J.1460-9568.2000.00940.X |
0.355 |
|
| 2000 |
Koponen S, Goldsteins G, Keinänen R, Koistinaho J. Induction of protein kinase Cdelta subspecies in neurons and microglia after transient global brain ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 93-102. PMID 10616797 DOI: 10.1097/00004647-200001000-00013 |
0.37 |
|
| 1999 |
Yrjänheikki J, Tikka T, Keinänen R, Goldsteins G, Chan PH, Koistinaho J. A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window. Proceedings of the National Academy of Sciences of the United States of America. 96: 13496-500. PMID 10557349 DOI: 10.1073/Pnas.96.23.13496 |
0.351 |
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| 1999 |
Vartiainen N, Tikka T, Keinänen R, Chan PH, Koistinaho J. Glutamatergic receptors regulate expression, phosphorylation and accumulation of neurofilaments in spinal cord neurons. Neuroscience. 93: 1123-33. PMID 10473276 DOI: 10.1016/S0306-4522(99)00200-6 |
0.333 |
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| 1999 |
Koistinaho J, Koponen S, Chan PH. Expression of cyclooxygenase-2 mRNA after global ischemia is regulated by AMPA receptors and glucocorticoids. Stroke. 30: 1900-5; discussion 1. PMID 10471443 DOI: 10.1161/01.Str.30.9.1900 |
0.347 |
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| 1999 |
Hökfelt T, Broberger C, Diez M, Xu ZQ, Shi T, Kopp J, Zhang X, Holmberg K, Landry M, Koistinaho J. Galanin and NPY, two peptides with multiple putative roles in the nervous system. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et MéTabolisme. 31: 330-4. PMID 10422730 DOI: 10.1055/S-2007-978748 |
0.353 |
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| 1999 |
Keinänen R, Vartiainen N, Koistinaho J. Molecular cloning and characterization of the rat inducible nitric oxide synthase (iNOS) gene. Gene. 234: 297-305. PMID 10395902 DOI: 10.1016/S0378-1119(99)00196-1 |
0.319 |
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| 1998 |
Yrjänheikki J, Keinänen R, Pellikka M, Hökfelt T, Koistinaho J. Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia. Proceedings of the National Academy of Sciences of the United States of America. 95: 15769-74. PMID 9861045 DOI: 10.1073/Pnas.95.26.15769 |
0.407 |
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| 1998 |
Hökfelt T, Broberger C, Zhang X, Diez M, Kopp J, Xu Z, Landry M, Bao L, Schalling M, Koistinaho J, DeArmond SJ, Prusiner S, Gong J, Walsh JH. Neuropeptide Y: some viewpoints on a multifaceted peptide in the normal and diseased nervous system. Brain Research. Brain Research Reviews. 26: 154-66. PMID 9651513 DOI: 10.1016/S0165-0173(97)00052-0 |
0.312 |
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| 1998 |
Keinänen R, Miettinen S, Yrjänheikki J, Koistinaho J. Induction of ornithine decarboxylase mRNA in transient focal cerebral ischemia in the rat. Neuroscience Letters. 239: 69-72. PMID 9469658 DOI: 10.1016/S0304-3940(97)00890-2 |
0.327 |
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| 1997 |
Wittner M, Sivenius J, Koistinaho J. Alpha2-adrenoreceptor agonist, dexmedetomidine, alters acute gene expression after global ischemia in gerbils. Neuroscience Letters. 232: 75-8. PMID 9302090 DOI: 10.1016/S0304-3940(97)00585-5 |
0.313 |
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| 1997 |
Lahtinen H, Koistinaho J, Kauppinen R, Haapalinna A, Keinänen R, Sivenius J. Selegiline treatment after transient global ischemia in gerbils enhances the survival of CA1 pyramidal cells in the hippocampus. Brain Research. 757: 260-267. PMID 9200755 DOI: 10.1016/S0006-8993(97)00227-8 |
0.319 |
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| 1997 |
Miettinen S, Fusco FR, Yrjänheikki J, Keinänen R, Hirvonen T, Roivainen R, Närhi M, Hökfelt T, Koistinaho J. Spreading depression and focal brain ischemia induce cyclooxygenase-2 in cortical neurons through N-methyl-D-aspartic acid-receptors and phospholipase A2. Proceedings of the National Academy of Sciences of the United States of America. 94: 6500-5. PMID 9177247 DOI: 10.1073/Pnas.94.12.6500 |
0.345 |
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| 1997 |
Koistinaho J, Pyykönen I, Keinänen R, Hökfelt T. Expression of beta-amyloid precursor protein mRNAs following transient focal ischaemia. Neuroreport. 7: 2727-31. PMID 8981456 DOI: 10.1097/00001756-199611040-00064 |
0.324 |
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| 1997 |
Usenius T, Tenhunen M, Koistinaho J. Ionizing radiation induces expression of immediate early genes in the rat brain. Neuroreport. 7: 2559-63. PMID 8981423 DOI: 10.1097/00001756-199611040-00031 |
0.323 |
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| 1997 |
Koistinaho J, Miettinen S, Keinänen R, Vartiainen N, Roivainen R, Laitinen JT. Long-term induction of haem oxygenase-1 (HSP-32) in astrocytes and microglia following transient focal brain ischaemia in the rat. The European Journal of Neuroscience. 8: 2265-72. PMID 8950091 DOI: 10.1111/J.1460-9568.1996.Tb01190.X |
0.361 |
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| 1997 |
Vartiainen N, Pyykönen I, Hökfelt T, Koistinaho J. Induction of thymosin beta(4) mRNA following focal brain ischemia. Neuroreport. 7: 1613-6. PMID 8904767 DOI: 10.1097/00001756-199607080-00017 |
0.325 |
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| 1996 |
Diez M, Koistinaho J, DeArmond SJ, Camerino AP, Groth D, Caytano JC, Prusiner SB, Hökfelt T. Aberrant induction of neuropeptide Y mRNA in hippocampal CA3 pyramidal neurones in scrapie-infected mice. Neuroreport. 7: 1887-92. PMID 8905686 DOI: 10.1097/00001756-199608120-00003 |
0.337 |
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| 1996 |
Roivainen R, Koistinaho J. Histochemical detection of age- and injury-related changes in signal transduction in the superior cervical ganglion. Microscopy Research and Technique. 35: 20-31. PMID 8873056 DOI: 10.1002/(Sici)1097-0029(19960901)35:1<20::Aid-Jemt3>3.0.Co;2-W |
0.337 |
|
| 1996 |
Lukkarainen J, Kauppinen RA, Koistinaho J, Alhonen LM, Jänne J. Cerebral energy metabolism and immediate early gene induction following severe incomplete ischaemia in transgenic mice overexpressing the human ornithine decarboxylase gene: evidence that putrescine is not neurotoxic in vivo. The European Journal of Neuroscience. 7: 1840-9. PMID 8528457 DOI: 10.1111/J.1460-9568.1995.Tb00704.X |
0.336 |
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| 1996 |
Miettinen S, Roivainen R, Keinänen R, Hökfelt T, Koistinaho J. Specific Induction of Protein Kinase Cδ Subspecies after Transient Middle Cerebral Artery Occlusion in the Rat Brain: Inhibition by MK-801 The Journal of Neuroscience. 16: 6236-6245. DOI: 10.1523/Jneurosci.16-19-06236.1996 |
0.363 |
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| 1995 |
Näkki R, Koistinaho J, Sharp FR, Sagar SM. Cerebellar toxicity of phencyclidine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 2097-108. PMID 7891155 DOI: 10.1523/Jneurosci.15-03-02097.1995 |
0.347 |
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| 1995 |
Koistinaho J, Sagar SM. Light-induced c-fos expression in amacrine cells in the rabbit retina Molecular Brain Research. 29: 53-63. PMID 7770001 DOI: 10.1016/0169-328X(94)00218-4 |
0.306 |
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| 1995 |
Lahtivirta S, Koistinaho J, Hervonen A. A subpopulation of large neurons of the sympathetic superior cervical ganglion innervates the NGF-rich submandibular salivary gland in young adult and aged mice. Journal of the Autonomic Nervous System. 50: 283-289. PMID 7714323 DOI: 10.1016/0165-1838(94)00099-6 |
0.303 |
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| 1995 |
Pelto-Huikko M, Dagerlind A, Kononen J, Lundberg J, Villar M, Koistinaho J, Bravo R, Hokfelt T. Neuronal regulation of c-fos, c-jun, and junB immediate-early genes in rat adrenal medulla The Journal of Neuroscience. 15: 1854-1868. DOI: 10.1523/Jneurosci.15-03-01854.1995 |
0.303 |
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| 1994 |
Kinouchi H, Sharp FR, Chan PH, Koistinaho J, Sagar SM, Yoshimoto T. Induction of NGFI-A mRNA following middle cerebral artery occlusion in rats: in situ hybridization study. Neuroscience Letters. 171: 163-6. PMID 8084481 DOI: 10.1016/0304-3940(94)90630-0 |
0.303 |
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| 1994 |
Sharp FR, Butman M, Koistinaho J, Aardalen K, Nakki R, Massa SM, Swanson RA, Sagar SM. Phencyclidine induction of the hsp 70 stress gene in injured pyramidal neurons is mediated via multiple receptors and voltage gated calcium channels. Neuroscience. 62: 1079-92. PMID 7845588 DOI: 10.1016/0306-4522(94)90345-X |
0.305 |
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| 1994 |
Liepe B, Stone C, Koistinaho J, Copenhagen D. Nitric oxide synthase in Muller cells and neurons of salamander and fish retina The Journal of Neuroscience. 14: 7641-7654. DOI: 10.1523/Jneurosci.14-12-07641.1994 |
0.313 |
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| 1993 |
Koistinaho J, Hicks KJ, Sagar SM. Long-term induction of c-jun mRNA and Jun protein in rabbit retinal ganglion cells following axotomy or colchicine treatment. Journal of Neuroscience Research. 34: 250-5. PMID 8450568 DOI: 10.1002/Jnr.490340213 |
0.315 |
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| 1993 |
Kinouchi H, Sharp FR, Hill MP, Koistinaho J, Sagar SM, Chan PH. Induction of 70-kDa heat shock protein and hsp70 mRNA following transient focal cerebral ischemia in the rat. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 13: 105-15. PMID 8416999 DOI: 10.1038/Jcbfm.1993.13 |
0.324 |
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| 1993 |
Hisanaga K, Sagar SM, Koistinaho J, Hicks KJ, Sharp FR. VIP-induced stellation and immediate early gene expression in astrocytes: effects of dexamethasone. Neuroscience Letters. 156: 57-60. PMID 8414190 DOI: 10.1016/0304-3940(93)90439-R |
0.322 |
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| 1993 |
Kinouchi H, Sharp FR, Koistinaho J, Hicks K, Kamii H, Chan PH. Induction of heat shock hsp70 mRNA and HSP70 kDa protein in neurons in the 'penumbra' following focal cerebral ischemia in the rat. Brain Research. 619: 334-8. PMID 8374789 DOI: 10.1016/0006-8993(93)91630-B |
0.316 |
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| 1993 |
Suhonen J, Koistinaho J, Hervonen A. Sympathetic neurons outlive the original host after transplantation to the rat submandibular gland. Neurobiology of Aging. 14: 383-387. PMID 8103574 DOI: 10.1016/0197-4580(93)90125-U |
0.305 |
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| 1993 |
Koistinaho J, Pelto-Huikko M, Sagar SM, Dagerlind A, Roivainen R, Hökfelt T. Injury-induced long-term expression of immediate early genes in the rat superior cervical ganglion. Neuroreport. 4: 37-40. PMID 8095820 DOI: 10.1097/00001756-199301000-00009 |
0.365 |
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| 1992 |
Honkaniemi J, Fuxe K, Rechard L, Koistinaho J, Isola J, Gustafsson J, Okret S, Pelto-Huikko M. Colocalization of fos- and glucocorticoid receptor-like immunoreactivities in the rat amygdaloid complex after immobilization stress. Journal of Neuroendocrinology. 4: 547-555. PMID 21554639 DOI: 10.1111/J.1365-2826.1992.Tb00203.X |
0.306 |
|
| 1992 |
Sharp FR, Butman M, Wang S, Koistinaho J, Graham SH, Sagar SM, Noble L, Berger P, Longo FM. Haloperidol prevents induction of the hsp70 heat shock gene in neurons injured by phencyclidine (PCP), MK801, and ketamine. Journal of Neuroscience Research. 33: 605-16. PMID 1484394 DOI: 10.1002/Jnr.490330413 |
0.309 |
|
| 1992 |
Lahtivirta S, Koistinaho J, Hervonen A. Effect of sialectomy on the superior cervical ganglion sympathetic neurons in young adult and aged mice. Mechanisms of Ageing and Development. 62: 25-33. PMID 1348565 DOI: 10.1016/0047-6374(92)90141-Y |
0.317 |
|
| 1991 |
Koistinaho J. Nicotine-induced Fos-like immunoreactivity in rat sympathetic ganglia and adrenal medulla Neuroscience Letters. 128: 47-51. PMID 1922947 DOI: 10.1016/0304-3940(91)90757-K |
0.327 |
|
| 1991 |
Koistinaho J, Hatanpaa KJ, Hervonen A. Light and electron microscopic features of peripheral ganglion cells cultured from young and aged Wistar rats. Mechanisms of Ageing and Development. 61: 23-32. PMID 1779699 DOI: 10.1016/0047-6374(91)90004-J |
0.306 |
|
| 1991 |
Suhonen J, Koistinaho J, Hervonen A. Histochemistry of sympathetic neurons allotransplanted from young and aged mice to the submandibular gland Experimental Neurology. 112: 104-111. PMID 1672851 DOI: 10.1016/0014-4886(91)90119-W |
0.302 |
|
| 1990 |
Koistinaho J. c-fos Protein-like immunoreactivity in cultured human glial cells Neuroscience Research. 9: 64-68. PMID 2175869 DOI: 10.1016/0168-0102(90)90047-I |
0.309 |
|
| 1990 |
Roivainen R, Koistinaho J. Decentralization induces long-term c-fos protein-like immunoreactivity in non-neuronal cells in the rat superior cervical ganglion Neuroscience Letters. 119: 105-108. PMID 2129059 DOI: 10.1016/0304-3940(90)90767-4 |
0.309 |
|
| 1990 |
Koistinaho J, Koljonen M, Roivainen R, Metsä-Ketelä T, Hervonen A. Immunohistochemical Detection Of C-Fos Proteins In Cultured Human Glial Cells : Induction By Cyclic Amp And Phorbol Ester Histochemistry and Cell Biology. 95: 143-147. PMID 2127926 DOI: 10.1007/Bf00266586 |
0.322 |
|
| 1990 |
Kononen J, Koistinaho J, Alho H. Circadian rhythm in c-fos-like immunoreactivity in the rat brain Neuroscience Letters. 120: 105-108. PMID 2127303 DOI: 10.1016/0304-3940(90)90179-D |
0.321 |
|
| 1990 |
Yang GA, Koistinaho J. Age-related increase in c-fos expression in the sympathetic neurons of the rat superior cervical ganglion. Brain Research. 533: 338-43. PMID 2126977 DOI: 10.1016/0006-8993(90)91360-S |
0.324 |
|
| 1990 |
Suhonen J, Koistinaho J, Hervonen A. Survival of both young and aged sympathetic neurons in the adrenal cortex after autotransplantation. Histochemistry and Cell Biology. 94: 591-595. PMID 1980677 DOI: 10.1007/Bf00271985 |
0.308 |
|
| 1990 |
Koistinaho J. Suramin-induced changes in sympathetic neurons: correlation between catecholamine fluorescence, tyrosine hydroxylase immunoreactivity and accumulation of pigment bodies. Neuroscience Letters. 112: 19-24. PMID 1974715 DOI: 10.1016/0304-3940(90)90315-Z |
0.301 |
|
| 1990 |
Koistinaho J, Hatanpää K, Hervonen A. Human paraganglion cells differentiate into adrenergic neurons in culture. Experimental Neurology. 107: 277-280. PMID 1968398 DOI: 10.1016/0014-4886(90)90146-J |
0.314 |
|
| 1989 |
Koistinaho J, Hervonen A. Neuronal degeneration and lipopigment formation in rat sympathetic ganglion after treatment with high-dose guanethidine. Neuroscience Letters. 102: 349-354. PMID 2812512 DOI: 10.1016/0304-3940(89)90104-3 |
0.312 |
|
| 1986 |
Koistinaho J, Sorvaniemi M, Alho H, Hervonen A. Microspectrofluorometric quantitation of autofluorescent lipopigment in the human sympathetic ganglia. Mechanisms of Ageing and Development. 37: 79-89. PMID 3821191 DOI: 10.1016/0047-6374(86)90120-X |
0.301 |
|
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