| Year |
Citation |
Score |
| 2023 |
Larouche M, Khoury E, Brisson D, Gaudet D. Inhibition of Angiopoietin-Like Protein 3 or 3/8 Complex and ApoC-III in Severe Hypertriglyceridemia. Current Atherosclerosis Reports. 25: 1101-1111. PMID 38095804 DOI: 10.1007/s11883-023-01179-y |
0.512 |
|
| 2023 |
Lauzière A, Brisson D, Tremblay G, Bédard S, Khoury E, Gaudet D. Comparison of the burden of familial hypercholesterolemia between two cohorts of French Canadians hospitalized 25 years apart for coronary heart disease. Journal of Clinical Lipidology. PMID 38030518 DOI: 10.1016/j.jacl.2023.10.008 |
0.599 |
|
| 2023 |
Larouche M, Brisson D, Morissette MC, Gaudet D. Post-prandial analysis of fluctuations in the platelet count and platelet function in patients with the familial chylomicronemia syndrome. Orphanet Journal of Rare Diseases. 18: 167. PMID 37370069 DOI: 10.1186/s13023-023-02743-0 |
0.567 |
|
| 2023 |
Brisson D, Larouche M, Chebli J, Khoury E, Gaudet D. Correlation between chylomicronemia diagnosis scores and post-heparin lipoprotein lipase activity. Clinical Biochemistry. 114: 67-72. PMID 36780934 DOI: 10.1016/j.clinbiochem.2023.02.002 |
0.592 |
|
| 2022 |
Sun CJ, McCudden C, Brisson D, Shaw J, Gaudet D, Ooi TC. Comparison of three methods for LDLC calculation for cardiovascular disease risk categorization in three distinct patient populations. The Canadian Journal of Cardiology. PMID 36586484 DOI: 10.1016/j.cjca.2022.12.025 |
0.52 |
|
| 2022 |
Roy N, Gaudet D, Brisson D. Palmar Striated Xanthomas in Clinical Practice. Journal of the Endocrine Society. 6: bvac103. PMID 35860753 DOI: 10.1210/jendso/bvac103 |
0.572 |
|
| 2022 |
Sun CJ, Brisson D, Sharma R, Birkett N, Gaudet D, Ooi TC. A More Atherogenic Lipoprotein Status Is Present in Adults With Than Without Type 2 Diabetes Mellitus With Equivalent Degrees of Hypertriglyceridemia. Canadian Journal of Diabetes. PMID 35718690 DOI: 10.1016/j.jcjd.2022.02.001 |
0.569 |
|
| 2021 |
Roy G, Couture P, Genest J, Ruel I, Baass A, Bergeron J, Brisson D, Brunham LR, Cermakova L, Gaudet D, Khoury E, Laflamme N, Kennedy BA, Hegele RA, Drouin-Chartier JP. Influence of the LDL-receptor genotype on statin response in heterozygous familial hypercholesterolemia: insights from the Canadian FH Registry. The Canadian Journal of Cardiology. PMID 34774719 DOI: 10.1016/j.cjca.2021.10.013 |
0.582 |
|
| 2021 |
Bchetnia M, Bouchard L, Mathieu J, Campeau P, Morin C, Brisson D, Laberge AM, Vézina H, Gaudet D, Laprise C. Genetic burden linked to founder effects in Saguenay-Lac-Saint-Jean illustrates the importance of genetic screening test availability. Journal of Medical Genetics. PMID 33910931 DOI: 10.1136/jmedgenet-2021-107809 |
0.527 |
|
| 2021 |
Maltais M, Brisson D, Gaudet D. Non-Alcoholic Fatty Liver in Patients with Chylomicronemia. Journal of Clinical Medicine. 10. PMID 33572376 DOI: 10.3390/jcm10040669 |
0.581 |
|
| 2020 |
Khoury E, Brisson D, Roy N, Tremblay G, Gaudet D. Identifying Markers of Cardiovascular Event-Free Survival in Familial Hypercholesterolemia. Journal of Clinical Medicine. 10. PMID 33375401 DOI: 10.3390/jcm10010064 |
0.591 |
|
| 2020 |
Sun CJ, Brisson D, Gaudet D, Ooi TC. Relative effect of hypertriglyceridemia on non-HDLC and apolipoprotein B as cardiovascular disease risk markers. Journal of Clinical Lipidology. PMID 33032940 DOI: 10.1016/j.jacl.2020.09.006 |
0.586 |
|
| 2020 |
Zheng KH, Kaiser Y, van Olden CC, Santos RD, Dasseux JL, Genest J, Gaudet D, Westerink J, Keyserling C, Verberne HJ, Leitersdorf E, Hegele RA, Descamps OS, Hopkins P, Nederveen AJ, et al. No benefit of HDL mimetic CER-001 on carotid atherosclerosis in patients with genetically determined very low HDL levels. Atherosclerosis. 311: 13-19. PMID 32919280 DOI: 10.1016/J.Atherosclerosis.2020.08.004 |
0.371 |
|
| 2020 |
Aljenedil S, Alothman L, Bélanger AM, Brown L, Lahijanian Z, Bergeron J, Couture P, Baass A, Ruel I, Brisson D, Khoury E, Gaudet D, Genest J. Lomitapide for treatment of homozygous familial hypercholesterolemia: The Québec experience. Atherosclerosis. 310: 54-63. PMID 32906018 DOI: 10.1016/J.Atherosclerosis.2020.07.028 |
0.637 |
|
| 2020 |
Santos RD, Ruzza A, Hovingh GK, Wiegman A, Mach F, Kurtz CE, Hamer A, Bridges I, Bartuli A, Bergeron J, Szamosi T, Santra S, Stefanutti C, Descamps OS, Greber-Platzer S, ... ... Gaudet D, et al. Evolocumab in Pediatric Heterozygous Familial Hypercholesterolemia. The New England Journal of Medicine. PMID 32865373 DOI: 10.1056/Nejmoa2019910 |
0.362 |
|
| 2020 |
Gaudet D, Karwatowska-Prokopczuk E, Baum SJ, Hurh E, Kingsbury J, Bartlett VJ, Figueroa AL, Piscitelli P, Singleton W, Witztum JL, Geary RS, Tsimikas S, St L O'Dea L. Vupanorsen, an N-acetyl galactosamine-conjugated antisense drug to ANGPTL3 mRNA, lowers triglycerides and atherogenic lipoproteins in patients with diabetes, hepatic steatosis, and hypertriglyceridaemia. European Heart Journal. PMID 32860031 DOI: 10.1093/Eurheartj/Ehaa689 |
0.333 |
|
| 2020 |
Raal FJ, Rosenson RS, Reeskamp LF, Hovingh GK, Kastelein JJP, Rubba P, Ali S, Banerjee P, Chan KC, Gipe DA, Khilla N, Pordy R, Weinreich DM, Yancopoulos GD, Zhang Y, ... Gaudet D, et al. Evinacumab for Homozygous Familial Hypercholesterolemia. The New England Journal of Medicine. 383: 711-720. PMID 32813947 DOI: 10.1056/Nejmoa2004215 |
0.421 |
|
| 2020 |
Tremblay K, Brisson D, Gaudet D. Gene expression profiles of recurrent acute pancreatitis risk in patients with sustained chylomicronemia. Endocrine Journal. PMID 32727960 DOI: 10.1507/Endocrj.Ej20-0123 |
0.585 |
|
| 2020 |
Blom DJ, Harada-Shiba M, Rubba P, Gaudet D, Kastelein JJP, Charng MJ, Pordy R, Donahue S, Ali S, Dong Y, Khilla N, Banerjee P, Baccara-Dinet M, Rosenson RS. Efficacy and Safety of Alirocumab in Adults With Homozygous Familial Hypercholesterolemia: The ODYSSEY HoFH Trial. Journal of the American College of Cardiology. 76: 131-142. PMID 32646561 DOI: 10.1016/J.Jacc.2020.05.027 |
0.387 |
|
| 2020 |
Tremblay K, Gaudet D, Khoury E, Brisson D. Dissection of Clinical and Gene Expression Signatures of Familial versus Multifactorial Chylomicronemia. Journal of the Endocrine Society. 4: bvaa056. PMID 32537545 DOI: 10.1210/Jendso/Bvaa056 |
0.616 |
|
| 2020 |
Gaudet D, Stevenson M, Komari N, Trentin G, Crowson C, Hadker N, Bernard S. The burden of familial chylomicronemia syndrome in Canadian patients. Lipids in Health and Disease. 19: 120. PMID 32487261 DOI: 10.1186/S12944-020-01302-X |
0.317 |
|
| 2020 |
Roy N, Gaudet D, Tremblay G, Brisson D. Association of common gene-smoking interactions with elevated plasma apolipoprotein B concentration. Lipids in Health and Disease. 19: 98. PMID 32430061 DOI: 10.1186/S12944-020-01287-7 |
0.637 |
|
| 2020 |
Sun CJ, McCudden C, Brisson D, Shaw J, Gaudet D, Ooi TC. Calculated Non-HDL Cholesterol Includes Cholesterol in Larger Triglyceride-Rich Lipoproteins in Hypertriglyceridemia. Journal of the Endocrine Society. 4: bvz010. PMID 32010872 DOI: 10.1210/Jendso/Bvz010 |
0.626 |
|
| 2020 |
Khoury E, Brisson D, Gaudet D. Preclinical discovery and development of evolocumab for the treatment of hypercholesterolemia. Expert Opinion On Drug Discovery. 1-12. PMID 31973581 DOI: 10.1080/17460441.2020.1704728 |
0.637 |
|
| 2020 |
Sliz E, Shin J, Syme C, Patel Y, Parker N, Richer L, Gaudet D, Bennett S, Paus T, Pausova Z. A variant near DHCR24 associates with microstructural properties of white matter and peripheral lipid metabolism in adolescents. Molecular Psychiatry. PMID 31900429 DOI: 10.1038/S41380-019-0640-9 |
0.322 |
|
| 2020 |
Sun C, Brisson D, McCudden C, Shaw J, Gaudet D, Ooi T. Comparison of the Effect of Hypertriglyceridemia on Non-HDL-Cholesterol and Apolipoprotein B as Cardiovascular Disease Risk Markers∗,† Journal of Clinical Lipidology. 14: 571-572. DOI: 10.1016/J.Jacl.2020.05.047 |
0.618 |
|
| 2020 |
Rosenson R, Raal F, Reeskamp L, Kastelein J, Baum S, Ali S, Banerjee P, Chan K, Gipe D, Pordy R, Gaudet D. The Efficacy and Safety of Evinacumab in Homozygous Familial Hypercholesterolemia Patients with Little to No Low-Density Lipoprotein Receptor Activity Journal of Clinical Lipidology. 14: 552. DOI: 10.1016/J.Jacl.2020.05.019 |
0.322 |
|
| 2019 |
O'Dea LSL, MacDougall J, Alexander VJ, Digenio A, Hubbard B, Arca M, Moriarty PM, Kastelein JJP, Bruckert E, Soran H, Witztum JL, Hegele RA, Gaudet D. Differentiating Familial Chylomicronemia Syndrome From Multifactorial Severe Hypertriglyceridemia by Clinical Profiles. Journal of the Endocrine Society. 3: 2397-2410. PMID 31777768 DOI: 10.1210/Js.2019-00214 |
0.306 |
|
| 2019 |
Guay SP, Houde AA, Breton E, Baillargeon JP, Perron P, Gaudet D, Hivert MF, Brisson D, Bouchard L. DNA methylation at gene locus mediates the association between maternal total cholesterol changes in pregnancy and cord blood leptin levels. Journal of Developmental Origins of Health and Disease. 1-10. PMID 31753053 DOI: 10.1017/S204017441900076X |
0.603 |
|
| 2019 |
Gaudet D, Durst R, Lepor N, Bakker-Arkema R, Bisgaier C, Masson L, Golden L, Kastelein JJ, Hegele RA, Stein E. Usefulness of Gemcabene in Homozygous Familial Hypercholesterolemia (from COBALT-1). The American Journal of Cardiology. PMID 31685212 DOI: 10.1016/J.Amjcard.2019.09.010 |
0.407 |
|
| 2019 |
Hegele RA, Borén J, Ginsberg HN, Arca M, Averna M, Binder CJ, Calabresi L, Chapman MJ, Cuchel M, von Eckardstein A, Frikke-Schmidt R, Gaudet D, Hovingh GK, Kronenberg F, Lütjohann D, et al. Rare dyslipidaemias, from phenotype to genotype to management: a European Atherosclerosis Society task force consensus statement. The Lancet. Diabetes & Endocrinology. PMID 31582260 DOI: 10.1016/S2213-8587(19)30264-5 |
0.342 |
|
| 2019 |
Banerjee P, Chan KC, Tarabocchia M, Benito-Vicente A, Alves AC, Uribe KB, Bourbon M, Skiba PJ, Pordy R, Gipe DA, Gaudet D, Martin C. Functional Analysis of LDLR (Low-Density Lipoprotein Receptor) Variants in Patient Lymphocytes to Assess the Effect of Evinacumab in Homozygous Familial Hypercholesterolemia Patients With a Spectrum of LDLR Activity. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119313051. PMID 31578082 DOI: 10.1161/Atvbaha.119.313051 |
0.382 |
|
| 2019 |
Witztum JL, Gaudet D, Freedman SD, Alexander VJ, Digenio A, Williams KR, Yang Q, Hughes SG, Geary RS, Arca M, Stroes ESG, Bergeron J, Soran H, Civeira F, Hemphill L, et al. Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome. The New England Journal of Medicine. 381: 531-542. PMID 31390500 DOI: 10.1056/Nejmoa1715944 |
0.36 |
|
| 2019 |
Floyd JS, Bloch KM, Brody JA, Maroteau C, Siddiqui MK, Gregory R, Carr DF, Molokhia M, Liu X, Bis JC, Ahmed A, Liu X, Hallberg P, Yue QY, Magnusson PKE, ... ... Gaudet D, et al. Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing. Plos One. 14: e0218115. PMID 31242253 DOI: 10.1371/Journal.Pone.0218115 |
0.571 |
|
| 2019 |
Khoury E, Brisson D, Roy N, Tremblay G, Gaudet D. Review of the long-term safety of lomitapide: a microsomal triglycerides transfer protein inhibitor for treating homozygous familial hypercholesterolemia. Expert Opinion On Drug Safety. PMID 30945578 DOI: 10.1080/14740338.2019.1602606 |
0.633 |
|
| 2019 |
Laufs U, Banach M, Mancini GBJ, Gaudet D, Bloedon LT, Sterling LR, Kelly S, Stroes ESG. Efficacy and Safety of Bempedoic Acid in Patients With Hypercholesterolemia and Statin Intolerance. Journal of the American Heart Association. 8: e011662. PMID 30922146 DOI: 10.1161/Jaha.118.011662 |
0.35 |
|
| 2019 |
Lauziere A, Brisson D, Bedard S, Khoury E, Tremblay G, Barabas M, Gaudet D. 4944The contribution of familial hypercholesterolemia (FH) to premature coronary artery disease decreased by 2-fold between 1998 and 2018 in a founder population with high prevalence of FH European Heart Journal. 40. DOI: 10.1093/Eurheartj/Ehz746.0014 |
0.626 |
|
| 2019 |
Brisson D, Khoury E, Gaudet D. Free glycerol correlate with post-heparin lipoprotein lipase activity and contribute to differentiate familial vs. multifactorial chylomicronemia Journal of Clinical Lipidology. 13: e26. DOI: 10.1016/J.Jacl.2019.04.047 |
0.596 |
|
| 2019 |
Khoury E, Gaudet D, Brisson D. Correlation between chylomicronemia diagnosis scores and post-heparin lipoprotein lipase activity Journal of Clinical Lipidology. 13: e25-e26. DOI: 10.1016/J.Jacl.2019.04.046 |
0.561 |
|
| 2019 |
Carpentier AC, Frisch F, Brisson D, Gaudet D. Familial Chylomicronemia Syndrome is associated with increased dietary fatty acid spillover in the circulation despite lower total postprandial triglycerides Journal of Clinical Lipidology. 13: e25. DOI: 10.1016/J.Jacl.2019.04.045 |
0.599 |
|
| 2019 |
Gupta M, Zawadka M, Aljenedil S, Kajil M, Bewick D, Gaudet D, Hegele R, Lonn E, Ngui D, Alothman L, Ruel I, Singh N, Genest J. THE HIGH PREVALENCE OF FAMILIAL HYPERCHOLESTEROLEMIA IN A POPULATION OF ASCVD PATIENTS WITH LDL-C ABOVE TARGET: AN ANALYSIS FROM THE REACT REGISTRY Journal of the American College of Cardiology. 73: 90. DOI: 10.1016/J.Cjca.2018.07.374 |
0.318 |
|
| 2018 |
Brunham LR, Ruel I, Aljenedil S, Rivière JB, Baass A, Tu JV, Mancini GBJ, Raggi P, Gupta M, Couture P, Pearson GJ, Bergeron J, Francis GA, McCrindle BW, Morrison K, ... ... Gaudet D, et al. Canadian Cardiovascular Society Position Statement on Familial Hypercholesterolemia: Update 2018. The Canadian Journal of Cardiology. 34: 1553-1563. PMID 30527143 DOI: 10.1016/J.Cjca.2018.09.005 |
0.651 |
|
| 2018 |
Gaudet D, Langslet G, Gidding SS, Luirink IK, Ruzza A, Kurtz C, Lu C, Somaratne R, Raal FJ, Wiegman A. Efficacy, safety, and tolerability of evolocumab in pediatric patients with heterozygous familial hypercholesterolemia: Rationale and design of the HAUSER-RCT study. Journal of Clinical Lipidology. 12: 1199-1207. PMID 30318065 DOI: 10.1016/J.Jacl.2018.05.007 |
0.335 |
|
| 2018 |
Ruel I, Brisson D, Aljenedil S, Awan Z, Baass A, Bélanger A, Bergeron J, Bewick D, Brophy JM, Brunham LR, Couture P, Dufour R, Francis GA, Frohlich J, Gagné C, ... Gaudet D, et al. Simplified Canadian Definition for Familial Hypercholesterolemia. The Canadian Journal of Cardiology. PMID 30093300 DOI: 10.1016/J.Cjca.2018.05.015 |
0.633 |
|
| 2018 |
Tremblay M, Brisson D, Gaudet D. Association study between a polymorphic poly-T repeat sequence in the promoter of the somatostatin gene and metabolic syndrome. Bmc Medical Genetics. 19: 130. PMID 30053852 DOI: 10.1186/S12881-018-0641-6 |
0.618 |
|
| 2018 |
Dron JS, Wang J, Berberich AJ, Iacocca MA, Cao H, Yang P, Knoll J, Tremblay K, Brisson D, Netzer C, Gouni-Berthold I, Gaudet D, Hegele RA. Large-scale deletions of the ABCA1 gene in patients with hypoalphalipoproteinemia. Journal of Lipid Research. PMID 29866657 DOI: 10.1194/Jlr.P086280 |
0.636 |
|
| 2018 |
Hegele RA, Berberich AJ, Ban MR, Wang J, Digenio A, Alexander VJ, D'Erasmo L, Arca M, Jones A, Bruckert E, Stroes ES, Bergeron J, Civeira F, Witztum JL, Gaudet D. Clinical and biochemical features of different molecular etiologies of familial chylomicronemia. Journal of Clinical Lipidology. PMID 29748148 DOI: 10.1016/J.Jacl.2018.03.093 |
0.35 |
|
| 2018 |
Brown WV, Goldberg I, Duell B, Gaudet D. Roundtable discussion: Familial chylomicronemia syndrome: Diagnosis and management. Journal of Clinical Lipidology. PMID 29534878 DOI: 10.1016/J.Jacl.2018.02.018 |
0.369 |
|
| 2018 |
Kusters DM, Braamskamp MJAM, Langslet G, McCrindle BW, Cassiman D, Francis GA, Gagne C, Gaudet D, Morrison KM, Wiegman A, Turner T, Miller E, Raichlen J, Martin PD, Stein EA, et al. Response by Kusters et al to Letter Regarding Article, "Effect of Rosuvastatin on Carotid Intima-Media Thickness in Children With Heterozygous Familial Hypercholesterolemia: The CHARON Study (Hypercholesterolemia in Children and Adolescents Taking Rosuvastatin Open Label)". Circulation. 137: 641-642. PMID 29431667 DOI: 10.1161/Circulationaha.117.031676 |
0.344 |
|
| 2018 |
Blom D, Freedman S, Gelrud A, Digenio A, Alexander V, Williams K, Hsieh A, Gouni-Berthold I, Bruckert E, Stroes E, Geary R, Hughes S, Gaudet D. Treatment with volanesorsen (VLN) reduced triglycerides and pancreatitis in patients with familial chylomicronemia syndrome (FCS) and severe hypertriglyceridemia (sHTG) vs placebo: Results of the approach and compass studies Pancreatology. 18: S101. DOI: 10.1016/J.Pan.2018.05.273 |
0.317 |
|
| 2018 |
Ooi TC, Gaudet D, Brisson D, Tepliakova L, Figeys D, Mayne J. Circulating Soluble Low Density Lipoprotein Receptor Levels in Heterozygous Familial Hypercholesterolemia Subjects Before and After Statin Therapy Atherosclerosis Supplements. 32: 60-61. DOI: 10.1016/J.Atherosclerosissup.2018.04.182 |
0.611 |
|
| 2018 |
Brisson D, Tremblay K, Gaudet D. A Simple Clinical Diagnosis Scoring System Allowing to Identify Familial Form of Chylomicronemia Syndrome Atherosclerosis Supplements. 32: 57-58. DOI: 10.1016/J.Atherosclerosissup.2018.04.173 |
0.576 |
|
| 2018 |
Aljenedil S, Ruel I, Brisson D, Awan Z, Baass A, Bélanger A, Bewick D, Bergeron J, Brophy JM, Brunham LR, Couture P, Dufour R, Francis GA, Frohlich J, Gagné C, ... Gaudet D, et al. Canadian Definition for Familial Hypercholesterolemia Atherosclerosis Supplements. 32: 55-56. DOI: 10.1016/J.Atherosclerosissup.2018.04.167 |
0.577 |
|
| 2018 |
Khoury E, Brisson D, Roy N, Tremblay G, Gaudet D. Surviving Familial Hypercholesterolemia without Coronary Artery Disease: A Unique Phenomenon Associated with Newly Identified Biological and Genetic Markers Atherosclerosis Supplements. 32: 51. DOI: 10.1016/J.Atherosclerosissup.2018.04.154 |
0.597 |
|
| 2018 |
Tremblay K, Brisson D, Gaudet D. Long-term Post LPL Gene Replacement Therapy Gene Expression Profile in Patients with Complete LPL Deficiency Atherosclerosis Supplements. 32: 50. DOI: 10.1016/J.Atherosclerosissup.2018.04.149 |
0.587 |
|
| 2018 |
Tremblay K, Brisson D, Gaudet D. Lipoprotein lipase gene replacement therapy long-term effect on familial hyperchylomicronemia gene expression profile Atherosclerosis. 275: e34. DOI: 10.1016/J.Atherosclerosis.2018.06.086 |
0.61 |
|
| 2018 |
Henry P, Cariou B, Averna M, Gaudet D, Lopez-Sendon JL, Drouot D, Chibedi-De-Roche D, Samuel R, Saubadu S, Kralova K, Huber K, Mertens A, Ceska R. Open-label ODYSSEY APPRISE study: Interim data from the first 843 participants Archives of Cardiovascular Diseases Supplements. 10: 127. DOI: 10.1016/J.Acvdsp.2017.11.166 |
0.308 |
|
| 2017 |
Steinhagen-Thiessen E, Stroes E, Arca M, Soran H, Moulin P, Gaudet D, Stulnig T, Johnson C, Rastelletti I, Dippel M, Averna MR. FIrst interim results of the global, longitudinal, pharmaco-epidemiologic, observational registry on gene therapy in the management of lipoprotein lipase deficiency (geniall). Atherosclerosis. 263: e66-e67. PMID 29366187 DOI: 10.1016/J.Atherosclerosis.2017.06.223 |
0.318 |
|
| 2017 |
Tremblay K, Brisson D, Gaudet D. Natural history and gene expression signature of platelet count in lipoprotein lipase deficiency. Atherosclerosis. 263: e100. PMID 29365429 DOI: 10.1016/J.Atherosclerosis.2017.06.325 |
0.594 |
|
| 2017 |
Ruel I, Aljenedil S, Sadri I, de Varennes É, Hegele RA, Couture P, Bergeron J, Wanneh E, Baass A, Dufour R, Gaudet D, Brisson D, Brunham LR, Francis GA, Cermakova L, et al. Imputation of Baseline LDL Cholesterol Concentration in Patients with Familial Hypercholesterolemia on Statins or Ezetimibe. Clinical Chemistry. PMID 29038147 DOI: 10.1373/Clinchem.2017.279422 |
0.657 |
|
| 2017 |
Stein EA, Dann EJ, Wiegman A, Skovby F, Gaudet D, Sokal E, Charng MJ, Mohamed M, Luirink I, Raichlen JS, Sundén M, Carlsson SC, Raal FJ, Kastelein JJP. Efficacy of Rosuvastatin in Children With Homozygous Familial Hypercholesterolemia and Association With Underlying Genetic Mutations. Journal of the American College of Cardiology. 70: 1162-1170. PMID 28838366 DOI: 10.1016/J.Jacc.2017.06.058 |
0.381 |
|
| 2017 |
Paquette M, Brisson D, Dufour R, Khoury É, Gaudet D, Baass A. Cardiovascular disease in familial hypercholesterolemia: Validation and refinement of the Montreal-FH-SCORE. Journal of Clinical Lipidology. PMID 28801029 DOI: 10.1016/J.Jacl.2017.07.008 |
0.62 |
|
| 2017 |
Rosenson RS, Brewer HB, Barter PJ, Björkegren JLM, Chapman MJ, Gaudet D, Kim DS, Niesor E, Rye KA, Sacks FM, Tardif JC, Hegele RA. HDL and atherosclerotic cardiovascular disease: genetic insights into complex biology. Nature Reviews. Cardiology. PMID 28795686 DOI: 10.1038/Nrcardio.2017.115 |
0.398 |
|
| 2017 |
Gaudet D, Gipe DA, Pordy R, Ahmad Z, Cuchel M, Shah PK, Chyu KY, Sasiela WJ, Chan KC, Brisson D, Khoury E, Banerjee P, Gusarova V, Gromada J, Stahl N, et al. ANGPTL3 Inhibition in Homozygous Familial Hypercholesterolemia. The New England Journal of Medicine. 377: 296-297. PMID 28723334 DOI: 10.1056/Nejmc1705994 |
0.599 |
|
| 2017 |
Blom DJ, Averna MR, Meagher EA, du Toit Theron H, Sirtori CR, Hegele RA, Shah PK, Gaudet D, Stefanutti C, Vigna GB, Larrey D, Bloedon LT, Foulds P, Rader DJ, Cuchel M. Long-Term Efficacy and Safety of the Microsomal Triglyceride Transfer Protein Inhibitor Lomitapide in Patients With Homozygous Familial Hypercholesterolemia. Circulation. 136: 332-335. PMID 28716835 DOI: 10.1161/Circulationaha.117.028208 |
0.37 |
|
| 2017 |
Gagné-Ouellet V, Houde AA, Guay SP, Perron P, Gaudet D, Guérin R, Baillargeon JP, Hivert MF, Brisson D, Bouchard L. Placental lipoprotein lipase DNA methylation alterations are associated with gestational diabetes and body composition at 5 years of age. Epigenetics. 0. PMID 28486003 DOI: 10.1080/15592294.2017.1322254 |
0.578 |
|
| 2017 |
Gaudet D, Drouin-Chartier JP, Couture P. Lipid Metabolism and Emerging Targets for Lipid-Lowering Therapy. The Canadian Journal of Cardiology. PMID 28365054 DOI: 10.1016/J.Cjca.2016.12.019 |
0.392 |
|
| 2017 |
Liu C, Gaudet D, Miller YI. Deficient Cholesterol Esterification in Plasma of apoc2 Knockout Zebrafish and Familial Chylomicronemia Patients. Plos One. 12: e0169939. PMID 28107429 DOI: 10.1371/Journal.Pone.0169939 |
0.383 |
|
| 2017 |
Hovingh G, Gipe D, Ahmad Z, Cuchel M, Shah P, Chyu K, Pordy R, Sasiela W, Chan K, Khoury E, Gaudet D. 5938Efficacy of evinacumab in homozygous familial hypercholesterolemia patients with null or non-null LDL-receptor mutations and on various background therapies European Heart Journal. 38. DOI: 10.1093/Eurheartj/Ehx493.5938 |
0.32 |
|
| 2017 |
Gaudet D, Baass A, Tremblay K, Brisson D, Laflamme N, Paquette M, Dufour R, Bergeron J. Natural History (up to 15 years) of Platelet Count in 84 Patients with Familial Hyperchylomicronemia Due to Lipoprotein Lipase Deficiency Journal of Clinical Lipidology. 11: 797-798. DOI: 10.1016/J.Jacl.2017.04.043 |
0.595 |
|
| 2017 |
Tremblay K, Brisson D, Gaudet D. Gene Expression Signature of Platelet Count in Lipoprotein Lipase Deficiency Journal of Clinical Lipidology. 11: 795. DOI: 10.1016/J.Jacl.2017.04.039 |
0.592 |
|
| 2017 |
Baass A, Paquette M, Brisson D, Dufour R, Gaudet D. Predicting Cardiovascular Events in Familial Hypercholesterolemia: Validation of the Montreal-FH-SCORE Journal of Clinical Lipidology. 11: 781. DOI: 10.1016/J.Jacl.2017.04.018 |
0.575 |
|
| 2016 |
Dufour R, Bergeron J, Gaudet D, Weiss R, Hovingh GK, Qing Z, Yang F, Andisik M, Torri A, Pordy R, Gipe DA. Open-label therapy with alirocumab in patients with heterozygous familial hypercholesterolemia: Results from three years of treatment. International Journal of Cardiology. 228: 754-760. PMID 27886619 DOI: 10.1016/J.Ijcard.2016.11.046 |
0.311 |
|
| 2016 |
Gaudet D, Watts GF, Robinson JG, Minini P, Sasiela WJ, Edelberg J, Louie MJ, Raal FJ. Effect of Alirocumab on Lipoprotein(a) Over ≥1.5 Years (from the Phase 3 ODYSSEY Program). The American Journal of Cardiology. PMID 27793396 DOI: 10.1016/J.Amjcard.2016.09.010 |
0.321 |
|
| 2016 |
Syme C, Czajkowski S, Shin J, Abrahamowicz M, Leonard G, Perron M, Richer L, Veillette S, Gaudet D, Strug L, Wang Y, Xu H, Taylor G, Paus T, Bennett S, et al. Glycerophosphocholine Metabolites and Cardiovascular Disease Risk Factors in Adolescents: A Cohort Study. Circulation. PMID 27756781 DOI: 10.1161/Circulationaha.116.022993 |
0.303 |
|
| 2016 |
Stroes E, Guyton JR, Lepor N, Civeira F, Gaudet D, Watts GF, Baccara-Dinet MT, Lecorps G, Manvelian G, Farnier M. Efficacy and Safety of Alirocumab 150 mg Every 4 Weeks in Patients With Hypercholesterolemia Not on Statin Therapy: The ODYSSEY CHOICE II Study. Journal of the American Heart Association. 5. PMID 27625344 DOI: 10.1161/Jaha.116.003421 |
0.322 |
|
| 2016 |
Farnier M, Gaudet D, Valcheva V, Minini P, Miller K, Cariou B. Efficacy of alirocumab in high cardiovascular risk populations with or without heterozygous familial hypercholesterolemia: Pooled analysis of eight ODYSSEY Phase 3 clinical program trials. International Journal of Cardiology. 223: 750-757. PMID 27573600 DOI: 10.1016/J.Ijcard.2016.08.273 |
0.37 |
|
| 2016 |
Gaudet D, Stroes ES, Methot J, Brisson D, Tremblay K, Bernelot Moens SJ, Iotti G, Rastelletti I, Ardigo D, Corzo D, Meyer C, Andersen M, Ruszniewski P, Deakin M, Bruno MJ. A Long-Term (up to 6 years) Retrospective Analysis of Gene Therapy with Alipogene Tiparvovec and its Effect on Lipoprotein Lipase Deficiency (LPLD)-Induced Pancreatitis. Human Gene Therapy. PMID 27412455 DOI: 10.1089/Hum.2015.158 |
0.604 |
|
| 2016 |
Côté S, Gagné-Ouellet V, Guay SP, Allard C, Houde AA, Perron P, Baillargeon JP, Gaudet D, Guérin R, Brisson D, Hivert MF, Bouchard L. PPARGC1α gene DNA methylation variations in human placenta mediate the link between maternal hyperglycemia and leptin levels in newborns. Clinical Epigenetics. 8: 72. PMID 27340502 DOI: 10.1186/S13148-016-0239-9 |
0.589 |
|
| 2016 |
Besseling J, Reitsma JB, Gaudet D, Brisson D, Kastelein JJ, Hovingh GK, Hutten BA. Selection of individuals for genetic testing for familial hypercholesterolaemia: development and external validation of a prediction model for the presence of a mutation causing familial hypercholesterolaemia. European Heart Journal. PMID 27044878 DOI: 10.1093/Eurheartj/Ehw135 |
0.592 |
|
| 2016 |
Guay SP, Légaré C, Brisson D, Mathieu P, Bossé Y, Gaudet D, Bouchard L. Epigenetic and genetic variations at the TNNT1 gene locus are associated with HDL-C levels and coronary artery disease. Epigenomics. 8: 359-71. PMID 26950807 DOI: 10.2217/Epi.15.120 |
0.639 |
|
| 2016 |
Gaudet D. Novel therapies for severe dyslipidemia originating from human genetics. Current Opinion in Lipidology. 27: 112-24. PMID 26849851 DOI: 10.1097/Mol.0000000000000281 |
0.344 |
|
| 2016 |
Tremblay M, Brisson D, Gaudet D. Association between a polymorphic poly-T repeat sequence in the promoter of the somatostatin gene and hypertension. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 39: 467-74. PMID 26818653 DOI: 10.1038/Hr.2016.4 |
0.588 |
|
| 2016 |
Stein EA, Dann EJ, Wiegman A, Skovby F, Gaudet D, Sokal E, Charng M, Mohamed M, Carlsson S, Raichlen J, Kastelein J. A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTI-CENTER, CROSS-OVER STUDY OF ROSUVASTATIN IN CHILDREN AND ADOLESCENTS (AGED 6 TO <18 YEARS) WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HOFH) Journal of the American College of Cardiology. 67: 1855. DOI: 10.1016/S0735-1097(16)31856-3 |
0.303 |
|
| 2016 |
Gaudet D, Gipe DA, Pordy R, Sasiela W, Chan K, Khoury E. Safety and efficacy of evinacumab, a monoclonal antibody to ANGPTL3, in patients with homozygous familial hypercholesterolemia receiving concomitant lipid-lowering therapies Journal of Clinical Lipidology. 10: 715. DOI: 10.1016/J.Jacl.2016.03.091 |
0.31 |
|
| 2016 |
Tremblay K, Brisson D, Gaudet D. Gene Expression Signature of Recurrent Acute Pancreatitis Risk in LPL Deficiency and Severe Hypertriglyceridemia Journal of Clinical Lipidology. 10: 681. DOI: 10.1016/J.Jacl.2016.03.049 |
0.585 |
|
| 2016 |
Roy N, Gaudet D, Brisson D. Association Between Frequent Gene-Smoking Interactions And Plama Apolipoprotein B Levels Among Low-Risk Individuals Journal of Clinical Lipidology. 10: 671-672. DOI: 10.1016/J.Jacl.2016.03.039 |
0.585 |
|
| 2016 |
Khoury E, Brisson D, Roy N, Tremblay K, Tremblay G, Gaudet D. Environmental and Biological Markers of Survival in Septuagenarians and Octogenarians Carrying FH-Causing LDLR Gene Mutations* Journal of Clinical Lipidology. 10: 671. DOI: 10.1016/J.Jacl.2016.03.038 |
0.573 |
|
| 2016 |
Gaudet D, Brisson D, Tremblay K. Genetic and Functional investigation of LPL Independent Pathways of TG-Rich Lipoproteins Catabolism in Severe Hypertriglyceridemia and Chylomicronemia Journal of Clinical Lipidology. 10: 664. DOI: 10.1016/J.Jacl.2016.03.028 |
0.595 |
|
| 2016 |
Gaudet D, Brisson D, Tremblay K. Investigation of LPL independent pathways of TG-rich lipoprotein metabolism in LPL deficiency Atherosclerosis. 252: e120. DOI: 10.1016/J.Atherosclerosis.2016.07.637 |
0.593 |
|
| 2015 |
Gaudet D, Brisson D. Gene-based therapies in lipidology: current status and future challenges. Current Opinion in Lipidology. 26: 553-65. PMID 26780008 DOI: 10.1097/Mol.0000000000000240 |
0.593 |
|
| 2015 |
Braamskamp MJ, Langslet G, McCrindle BW, Cassiman D, Francis GA, Gagné C, Gaudet D, Morrison KM, Wiegman A, Turner T, Kusters DM, Miller E, Raichlen JS, Wissmar J, Martin PD, et al. Efficacy and safety of rosuvastatin therapy in children and adolescents with familial hypercholesterolemia: Results from the CHARON study. Journal of Clinical Lipidology. 9: 741-50. PMID 26687694 DOI: 10.1016/J.Jacl.2015.07.011 |
0.327 |
|
| 2015 |
Villeneuve S, Brisson D, Gaudet D. Influence of Abdominal Obesity on the Lipid-Lipoprotein Profile in Apoprotein E2/4 Carriers: The Effect of an Apparent Duality. Journal of Lipids. 2015: 742408. PMID 26605088 DOI: 10.1155/2015/742408 |
0.623 |
|
| 2015 |
Houde AA, Ruchat SM, Allard C, Baillargeon JP, St-Pierre J, Perron P, Gaudet D, Brisson D, Hivert MF, Bouchard L. LRP1B, BRD2 and CACNA1D: new candidate genes in fetal metabolic programming of newborns exposed to maternal hyperglycemia. Epigenomics. PMID 26586120 DOI: 10.2217/Epi.15.72 |
0.714 |
|
| 2015 |
Gaudet D, Alexander VJ, Baker BF, Brisson D, Tremblay K, Singleton W, Geary RS, Hughes SG, Viney NJ, Graham MJ, Crooke RM, Witztum JL, Brunzell JD, Kastelein JJ. Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia. The New England Journal of Medicine. 373: 438-47. PMID 26222559 DOI: 10.1056/Nejmoa1400283 |
0.606 |
|
| 2015 |
Bays H, Gaudet D, Weiss R, Ruiz JL, Watts GF, Gouni-Berthold I, Robinson J, Zhao J, Hanotin C, Donahue S. Alirocumab as Add-on To Atorvastatin Versus Other Lipid Treatment Strategies: ODYSSEY OPTIONS I Randomized Trial. The Journal of Clinical Endocrinology and Metabolism. jc20151520. PMID 26030325 DOI: 10.1210/Jc.2015-1520 |
0.366 |
|
| 2015 |
Hovingh GK, Smits LP, Stefanutti C, Soran H, Kwok S, de Graaf J, Gaudet D, Keyserling CH, Klepp H, Frick J, Paolini JF, Dasseux JL, Kastelein JJ, Stroes ES. The effect of an apolipoprotein A-I-containing high-density lipoprotein-mimetic particle (CER-001) on carotid artery wall thickness in patients with homozygous familial hypercholesterolemia: The Modifying Orphan Disease Evaluation (MODE) study. American Heart Journal. 169: 736-742.e1. PMID 25965722 DOI: 10.1016/J.Ahj.2015.01.008 |
0.404 |
|
| 2015 |
Stefanutti C, Blom DJ, Averna MR, Meagher EA, Theron Hd, Marais AD, Hegele RA, Sirtori CR, Shah PK, Gaudet D, Vigna GB, Sachais BS, Di Giacomo S, du Plessis AM, Bloedon LT, et al. The lipid-lowering effects of lomitapide are unaffected by adjunctive apheresis in patients with homozygous familial hypercholesterolaemia - a post-hoc analysis of a Phase 3, single-arm, open-label trial. Atherosclerosis. 240: 408-14. PMID 25897792 DOI: 10.1016/J.Atherosclerosis.2015.03.014 |
0.383 |
|
| 2015 |
Meyers CD, Tremblay K, Amer A, Chen J, Jiang L, Gaudet D. Effect of the DGAT1 inhibitor pradigastat on triglyceride and apoB48 levels in patients with familial chylomicronemia syndrome. Lipids in Health and Disease. 14: 8. PMID 25889044 DOI: 10.1186/S12944-015-0006-5 |
0.359 |
|
| 2015 |
Guay SP, Brisson D, Mathieu P, Bossé Y, Gaudet D, Bouchard L. A study in familial hypercholesterolemia suggests reduced methylomic plasticity in men with coronary artery disease. Epigenomics. 7: 17-34. PMID 25687463 DOI: 10.2217/Epi.14.64 |
0.584 |
|
| 2015 |
Raal FJ, Stein EA, Dufour R, Turner T, Civeira F, Burgess L, Langslet G, Scott R, Olsson AG, Sullivan D, Hovingh GK, Cariou B, Gouni-Berthold I, Somaratne R, Bridges I, ... ... Gaudet D, et al. PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2): a randomised, double-blind, placebo-controlled trial. Lancet. 385: 331-40. PMID 25282519 DOI: 10.1016/S0140-6736(14)61399-4 |
0.399 |
|
| 2015 |
Gaudet D, Brisson D. Gene-based therapies in lipidology: Current status and future challenges Current Opinion in Lipidology. 26: 553-565. DOI: 10.1097/MOL.0000000000000240 |
0.525 |
|
| 2015 |
Bernelot Moens SJ, Stroes ES, Andersen M, Meyer C, Brisson D, Bruno M, Gaudet D. Effect of gene therapy with alipogene tiparvovec on the incidence of pancreatitis in patients with lipoprotein lipase deficiency Pancreatology. 15: S53-S54. DOI: 10.1016/J.Pan.2015.05.212 |
0.608 |
|
| 2015 |
Gaudet D, Bernelot-Moens S, Zhou Y, Keefe D, Wright M, Patel S, Stroes ES. Pradigastat, a Diacylglycerol Acyltransferase 1 Inhibitor, Reduces Fasting Triglyceride Levels in Familial Chylomicronemia Journal of Clinical Lipidology. 9: 449-450. DOI: 10.1016/J.Jacl.2015.03.065 |
0.314 |
|
| 2015 |
Bernelot-Moens S, Stroes E, Carpentier A, Brisson D, Andersen M, Meyer C, Bruno M, Gaudet D. Gene therapy for lipoprotein lipase deficiency (LPLD): Final results of 3 prospective gene therapy clinical studies and 1 retrospective clinical events analysis Atherosclerosis. 241: e26. DOI: 10.1016/J.Atherosclerosis.2015.04.100 |
0.596 |
|
| 2014 |
Rosenson RS, Davidson MH, Hirsh BJ, Kathiresan S, Gaudet D. Genetics and causality of triglyceride-rich lipoproteins in atherosclerotic cardiovascular disease. Journal of the American College of Cardiology. 64: 2525-40. PMID 25500239 DOI: 10.1016/J.Jacc.2014.09.042 |
0.37 |
|
| 2014 |
Gaudet D, Brisson D, Tremblay K, Alexander VJ, Singleton W, Hughes SG, Geary RS, Baker BF, Graham MJ, Crooke RM, Witztum JL. Targeting APOC3 in the familial chylomicronemia syndrome. The New England Journal of Medicine. 371: 2200-6. PMID 25470695 DOI: 10.1056/Nejmoa1400284 |
0.639 |
|
| 2014 |
Genest J, Hegele RA, Bergeron J, Brophy J, Carpentier A, Couture P, Davignon J, Dufour R, Frohlich J, Gaudet D, Gupta M, Krisnamoorthy P, Mancini J, McCrindle B, et al. Canadian Cardiovascular Society position statement on familial hypercholesterolemia. The Canadian Journal of Cardiology. 30: 1471-81. PMID 25448461 DOI: 10.1016/J.Cjca.2014.09.028 |
0.652 |
|
| 2014 |
Villeneuve S, Brisson D, Marchant NL, Gaudet D. The potential applications of Apolipoprotein E in personalized medicine. Frontiers in Aging Neuroscience. 6: 154. PMID 25071563 DOI: 10.3389/Fnagi.2014.00154 |
0.592 |
|
| 2014 |
Gaudet D, Kereiakes DJ, McKenney JM, Roth EM, Hanotin C, Gipe D, Du Y, Ferrand AC, Ginsberg HN, Stein EA. Effect of alirocumab, a monoclonal proprotein convertase subtilisin/kexin 9 antibody, on lipoprotein(a) concentrations (a pooled analysis of 150 mg every two weeks dosing from phase 2 trials). The American Journal of Cardiology. 114: 711-5. PMID 25060413 DOI: 10.1016/J.Amjcard.2014.05.060 |
0.32 |
|
| 2014 |
Houde AA, St-Pierre J, Hivert MF, Baillargeon JP, Perron P, Gaudet D, Brisson D, Bouchard L. Placental lipoprotein lipase DNA methylation levels are associated with gestational diabetes mellitus and maternal and cord blood lipid profiles. Journal of Developmental Origins of Health and Disease. 5: 132-41. PMID 24847699 DOI: 10.1017/S2040174414000038 |
0.716 |
|
| 2014 |
Desgagné V, Hivert MF, St-Pierre J, Guay SP, Baillargeon JP, Perron P, Gaudet D, Brisson D, Bouchard L. Epigenetic dysregulation of the IGF system in placenta of newborns exposed to maternal impaired glucose tolerance. Epigenomics. 6: 193-207. PMID 24811788 DOI: 10.2217/Epi.14.3 |
0.688 |
|
| 2014 |
Tremblay K, Dubois-Bouchard C, Brisson D, Gaudet D. Association of CTRC and SPINK1 gene variants with recurrent hospitalizations for pancreatitis or acute abdominal pain in lipoprotein lipase deficiency. Frontiers in Genetics. 5: 90. PMID 24795752 DOI: 10.3389/Fgene.2014.00090 |
0.613 |
|
| 2014 |
Guay SP, Brisson D, Lamarche B, Biron S, Lescelleur O, Biertho L, Marceau S, Vohl MC, Gaudet D, Bouchard L. ADRB3 gene promoter DNA methylation in blood and visceral adipose tissue is associated with metabolic disturbances in men. Epigenomics. 6: 33-43. PMID 24579945 DOI: 10.2217/Epi.13.82 |
0.588 |
|
| 2014 |
Guay SP, Brisson D, Lamarche B, Gaudet D, Bouchard L. Epipolymorphisms within lipoprotein genes contribute independently to plasma lipid levels in familial hypercholesterolemia. Epigenetics : Official Journal of the Dna Methylation Society. 9: 718-29. PMID 24504152 DOI: 10.4161/Epi.27981 |
0.657 |
|
| 2014 |
Ferreira V, Twisk J, Kwikkers K, Aronica E, Brisson D, Methot J, Petry H, Gaudet D. Immune responses to intramuscular administration of alipogene tiparvovec (AAV1-LPL(S447X)) in a phase II clinical trial of lipoprotein lipase deficiency gene therapy. Human Gene Therapy. 25: 180-8. PMID 24299335 DOI: 10.1089/Hum.2013.169 |
0.574 |
|
| 2014 |
Tremblay M, Bouhali T, Gaudet D, Brisson D. Genealogical analysis as a new approach for the investigation of drug intolerance heritability. European Journal of Human Genetics : Ejhg. 22: 916-22. PMID 24281370 DOI: 10.1038/Ejhg.2013.270 |
0.605 |
|
| 2014 |
Langslet G, Braamskamp MJ, McCrindle B, Cassiman D, Francis G, Gagné C, Gaudet D, Morrison KM, Wiegman A, Turner T, Miller E, Raichlen J, Martin PG, Stein E, Kastelein J. EFFECT OF ROSUVASTATIN THERAPY ON ARTERIAL WALL CHANGES IN CHILDREN AND ADOLESCENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA: RESULTS FROM THE CHARON STUDY Journal of the American College of Cardiology. 63: A1379. DOI: 10.1016/S0735-1097(14)61379-6 |
0.31 |
|
| 2014 |
Tremblay K, Dubois-Bouchard C, Brisson D, Gaudet D. Pancreatitis in Severe Hypertriglyceridemia: Association of Gene Variants in Lipoprotein Lipase and Serine Protease Pathways with Increased Risk of Recurrent Hospitalizations* Journal of Clinical Lipidology. 8: 312. DOI: 10.1016/J.Jacl.2014.02.034 |
0.616 |
|
| 2014 |
Tremblay K, Dubois-Bouchard C, Brisson D, Gaudet D. Polymorphisms in protease-regulating genes are associated with recurrence of hospitalizations for acute abdominal pain in lipoprotein lipase deficiency Atherosclerosis. 235: e58. DOI: 10.1016/J.Atherosclerosis.2014.05.143 |
0.579 |
|
| 2013 |
Houde AA, Guay SP, Desgagné V, Hivert MF, Baillargeon JP, St-Pierre J, Perron P, Gaudet D, Brisson D, Bouchard L. Adaptations of placental and cord blood ABCA1 DNA methylation profile to maternal metabolic status. Epigenetics : Official Journal of the Dna Methylation Society. 8: 1289-302. PMID 24113149 DOI: 10.4161/Epi.26554 |
0.714 |
|
| 2013 |
Ruchat SM, Houde AA, Voisin G, St-Pierre J, Perron P, Baillargeon JP, Gaudet D, Hivert MF, Brisson D, Bouchard L. Gestational diabetes mellitus epigenetically affects genes predominantly involved in metabolic diseases. Epigenetics : Official Journal of the Dna Methylation Society. 8: 935-43. PMID 23975224 DOI: 10.4161/Epi.25578 |
0.722 |
|
| 2013 |
Brisson D, Perron P, Kahn HS, Gaudet D, Bouchard L. The lipid accumulation product for the early prediction of gestational insulin resistance and glucose dysregulation. Journal of Women's Health (2002). 22: 362-7. PMID 23717842 DOI: 10.1089/Jwh.2012.3807 |
0.566 |
|
| 2013 |
Guay SP, Brisson D, Lamarche B, Marceau P, Vohl MC, Gaudet D, Bouchard L. DNA methylation variations at CETP and LPL gene promoter loci: new molecular biomarkers associated with blood lipid profile variability. Atherosclerosis. 228: 413-20. PMID 23623643 DOI: 10.1016/J.Atherosclerosis.2013.03.033 |
0.632 |
|
| 2013 |
Gaudet D, Signorovitch J, Swallow E, Fan L, Tremblay K, Brisson D, Meyers C, Gruenberger JB. Medical resource use and costs associated with chylomicronemia. Journal of Medical Economics. 16: 657-66. PMID 23428107 DOI: 10.3111/13696998.2013.779277 |
0.587 |
|
| 2013 |
Tremblay JP, Xiao X, Aartsma-Rus A, Barbas C, Blau HM, Bogdanove AJ, Boycott K, Braun S, Breakefield XO, Bueren JA, Buschmann M, Byrne BJ, Calos M, Cathomen T, Chamberlain J, ... ... Gaudet D, et al. Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 266-8. PMID 23369965 DOI: 10.1038/Mt.2013.4 |
0.317 |
|
| 2013 |
Gagnon C, Chouinard MC, Laberge L, Brisson D, Gaudet D, Lavoie M, Leclerc N, Mathieu J. Prevalence of lifestyle risk factors in myotonic dystrophy type 1. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 40: 42-7. PMID 23250126 DOI: 10.1017/S0317167100012932 |
0.562 |
|
| 2013 |
Gaudet D, Méthot J, Déry S, Brisson D, Essiembre C, Tremblay G, Tremblay K, de Wal J, Twisk J, van den Bulk N, Sier-Ferreira V, van Deventer S. Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: an open-label trial. Gene Therapy. 20: 361-9. PMID 22717743 DOI: 10.1038/Gt.2012.43 |
0.62 |
|
| 2013 |
Guay SP, Gaudet D, Brisson D. The g.-469G>A polymorphism in the GPIHBP1 gene promoter is associated with hypertriglyceridemia and has an additive effect on the risk conferred by LPL defective alleles. Nutrition, Metabolism, and Cardiovascular Diseases : Nmcd. 23: 358-65. PMID 21978733 DOI: 10.1016/J.Numecd.2011.08.005 |
0.636 |
|
| 2013 |
Ruchat S, Houde A, St-Pierre J, Perron P, Baillargeon J, Gaudet D, Hivert M, Brisson D, Bouchard L. Gestational Diabetes Mellitus Epigenetically Predominantly Affects Genes Involved in Metabolic Diseases Canadian Journal of Diabetes. 37: S241. DOI: 10.1016/J.Jcjd.2013.03.150 |
0.592 |
|
| 2012 |
Guay SP, Voisin G, Brisson D, Munger J, Lamarche B, Gaudet D, Bouchard L. Epigenome-wide analysis in familial hypercholesterolemia identified new loci associated with high-density lipoprotein cholesterol concentration. Epigenomics. 4: 623-39. PMID 23244308 DOI: 10.2217/Epi.12.62 |
0.649 |
|
| 2012 |
Stein EA, Dufour R, Gagne C, Gaudet D, East C, Donovan JM, Chin W, Tribble DL, McGowan M. Apolipoprotein B synthesis inhibition with mipomersen in heterozygous familial hypercholesterolemia: results of a randomized, double-blind, placebo-controlled trial to assess efficacy and safety as add-on therapy in patients with coronary artery disease. Circulation. 126: 2283-92. PMID 23060426 DOI: 10.1161/Circulationaha.112.104125 |
0.376 |
|
| 2012 |
Tremblay M, Brisson D, Gaudet D. Association between salivary pH and metabolic syndrome in women: a cross-sectional study. Bmc Oral Health. 12: 40. PMID 22958748 DOI: 10.1186/1472-6831-12-40 |
0.561 |
|
| 2012 |
Gaudet D, Méthot J, Kastelein J. Gene therapy for lipoprotein lipase deficiency. Current Opinion in Lipidology. 23: 310-20. PMID 22691709 DOI: 10.1097/Mol.0B013E3283555A7E |
0.373 |
|
| 2012 |
Stein EA, Gipe D, Bergeron J, Gaudet D, Weiss R, Dufour R, Wu R, Pordy R. Effect of a monoclonal antibody to PCSK9, REGN727/SAR236553, to reduce low-density lipoprotein cholesterol in patients with heterozygous familial hypercholesterolaemia on stable statin dose with or without ezetimibe therapy: a phase 2 randomised controlled trial. Lancet. 380: 29-36. PMID 22633824 DOI: 10.1016/S0140-6736(12)60771-5 |
0.345 |
|
| 2012 |
Carpentier AC, Frisch F, Labbé SM, Gagnon R, de Wal J, Greentree S, Petry H, Twisk J, Brisson D, Gaudet D. Effect of alipogene tiparvovec (AAV1-LPL(S447X)) on postprandial chylomicron metabolism in lipoprotein lipase-deficient patients. The Journal of Clinical Endocrinology and Metabolism. 97: 1635-44. PMID 22438229 DOI: 10.1210/Jc.2011-3002 |
0.61 |
|
| 2012 |
Mammen AL, Gaudet D, Brisson D, Christopher-Stine L, Lloyd TE, Leffell MS, Zachary AA. Increased frequency of DRB1*11:01 in anti-hydroxymethylglutaryl-coenzyme A reductase-associated autoimmune myopathy. Arthritis Care & Research. 64: 1233-7. PMID 22422616 DOI: 10.1002/Acr.21671 |
0.559 |
|
| 2012 |
Guay SP, Brisson D, Munger J, Lamarche B, Gaudet D, Bouchard L. ABCA1 gene promoter DNA methylation is associated with HDL particle profile and coronary artery disease in familial hypercholesterolemia. Epigenetics : Official Journal of the Dna Methylation Society. 7: 464-72. PMID 22419126 DOI: 10.4161/Epi.19633 |
0.649 |
|
| 2012 |
Tremblay M, Loucif Y, Methot J, Brisson D, Gaudet D. Salivary pH as a marker of plasma adiponectin concentrations in Women. Diabetology & Metabolic Syndrome. 4: 4. PMID 22304893 DOI: 10.1186/1758-5996-4-4 |
0.578 |
|
| 2012 |
Méthot J, Brisson D, Gaudet D. On-site management of investigational products and drug delivery systems in conformity with Good Clinical Practices (GCPs). Clinical Trials (London, England). 9: 265-71. PMID 22222352 DOI: 10.1177/1740774511431280 |
0.55 |
|
| 2012 |
Mammen AL, Pak K, Williams EK, Brisson D, Coresh J, Selvin E, Gaudet D. Rarity of anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase antibodies in statin users, including those with self-limited musculoskeletal side effects. Arthritis Care & Research. 64: 269-72. PMID 21972203 DOI: 10.1002/Acr.20662 |
0.555 |
|
| 2012 |
Blackburn P, Lemieux I, Lamarche B, Bergeron J, Perron P, Tremblay G, Gaudet D, Després JP. Hypertriglyceridemic waist: a simple clinical phenotype associated with coronary artery disease in women. Metabolism: Clinical and Experimental. 61: 56-64. PMID 21733531 DOI: 10.1016/J.Metabol.2011.05.017 |
0.326 |
|
| 2012 |
Bruno MJ, de Wal J, Twisk J, Gaudet D, Miller N. Mo1209 Is Postprandial Chylomicronemia More Important Than Plasma Total Triglyceride Concentration in the Etiology of Recurrent Acute Pancreatitis in Lipoprotein Lipase Deficiency? Gastroenterology. 142: S-622. DOI: 10.1016/S0016-5085(12)62389-0 |
0.305 |
|
| 2012 |
Bruno MJ, Deakin M, Ruszniewski PB, Bulk NV, de Wal J, Camozzi CR, Gaudet D. 557 Alipogene Tiparvovec Gene Therapy Reduces the Risk of Acute Pancreatitis in Patients With Lipoprotein Lipase Deficiency Gastroenterology. 142: S-112. DOI: 10.1016/S0016-5085(12)60422-3 |
0.346 |
|
| 2012 |
Deakin M, De Wal J, Camozzi C, Bruno M, Ruszniewski P, Gaudet D. Pancreatitis in patients with lipoprotein lipase deficiency and the effect of alipogene tiparvovec (AAV1-LPLS447X gene therapy) Pancreatology. 12: e12. DOI: 10.1016/J.Pan.2012.03.030 |
0.341 |
|
| 2012 |
Meyers C, Gaudet D, Tremblay K, Amer A, Chen J, Aimin F. The DGAT1 Inhibitor LCQ908 Decreases Triglyceride Levels in Patients with the Familial Chylomicronemia Syndrome Journal of Clinical Lipidology. 6: 266-267. DOI: 10.1016/J.Jacl.2012.04.034 |
0.321 |
|
| 2011 |
Tremblay M, Gaudet D, Brisson D. Metabolic syndrome and oral markers of cardiometabolic risk. Journal (Canadian Dental Association). 77: b125. PMID 21975074 |
0.564 |
|
| 2011 |
Tremblay K, Méthot J, Brisson D, Gaudet D. Etiology and risk of lactescent plasma and severe hypertriglyceridemia. Journal of Clinical Lipidology. 5: 37-44. PMID 21262505 DOI: 10.1016/J.Jacl.2010.11.004 |
0.587 |
|
| 2011 |
Loucif Y, Méthot J, Tremblay K, Brisson D, Gaudet D. Contribution of adiponectin to the cardiometabolic risk of postmenopausal women with loss-of-function lipoprotein lipase gene mutations. Menopause (New York, N.Y.). 18: 558-62. PMID 21252727 DOI: 10.1097/Gme.0B013E3181Fca1D4 |
0.63 |
|
| 2011 |
Sirois-Gagnon D, Chamberland A, Perron S, Brisson D, Gaudet D, Laprise C. Association of common polymorphisms in the fractalkine receptor (CX3CR1) with obesity. Obesity (Silver Spring, Md.). 19: 222-7. PMID 20523302 DOI: 10.1038/Oby.2010.125 |
0.594 |
|
| 2011 |
Greentree S, Méthot J, Déry S, Tremblay K, de Wal J, van den Bulk N, Ruiterkamp G, Freidig A, Brisson D, Gaudet D. 35 ALIPOGENE TIPARVOVEC GENE THERAPY SIGNIFICANTLY REDUCES THE RISK OF PANCREATITIS IN LIPOPROTEIN LIPASE DEFICIENT PATIENTS Atherosclerosis Supplements. 12: 8. DOI: 10.1016/S1567-5688(11)70036-8 |
0.618 |
|
| 2011 |
Carpentier A, Frisch F, Labbé S, Méthot J, Gagné C, Déry S, Tremblay K, de Wal J, Twisk J, Greentree S, van den Bulk N, Brisson D, Gaudet D. 8 ALIPOGENE TIPARVOVEC GENE THERAPY ENHANCES POST-PRANDIAL CLEARANCE OF CHYLOMICRONS IN LIPOPROTEIN LIPASE DEFICIENT PATIENTS Atherosclerosis Supplements. 12: 2. DOI: 10.1016/S1567-5688(11)70009-5 |
0.611 |
|
| 2010 |
Brisson D, Méthot J, Tremblay K, Tremblay M, Perron P, Gaudet D. Comparison of the efficacy of fibrates on hypertriglyceridemic phenotypes with different genetic and clinical characteristics. Pharmacogenetics and Genomics. 20: 742-7. PMID 21217359 DOI: 10.1097/Fpc.0B013E328340095E |
0.589 |
|
| 2010 |
Gagnon C, Chouinard MC, Laberge L, Veillette S, Bégin P, Breton R, Jean S, Brisson D, Gaudet D, Mathieu J. Health supervision and anticipatory guidance in adult myotonic dystrophy type 1. Neuromuscular Disorders : Nmd. 20: 847-51. PMID 20884209 DOI: 10.1016/J.Nmd.2010.08.006 |
0.566 |
|
| 2010 |
van der Graaf A, Vissers MN, Gaudet D, Brisson D, Sivapalaratnam S, Roseboom TJ, Jansen AC, Kastelein JJ, Hutten BA. Dyslipidemia of mothers with familial hypercholesterolemia deteriorates lipids in adult offspring. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 2673-7. PMID 20864670 DOI: 10.1161/Atvbaha.110.209064 |
0.621 |
|
| 2010 |
Do R, Bailey SD, Paré G, Montpetit A, Desbiens K, Hudson TJ, Yusuf S, Bouchard C, Gaudet D, Pérusse L, Anand S, Vohl MC, Pastinen T, Engert JC. Fine mapping of the insulin-induced gene 2 identifies a variant associated with LDL cholesterol and total apolipoprotein B levels. Circulation. Cardiovascular Genetics. 3: 454-61. PMID 20858904 DOI: 10.1161/Circgenetics.109.917039 |
0.365 |
|
| 2010 |
Brisson D, Perron P, Guay SP, Gaudet D, Bouchard L. The "hypertriglyceridemic waist" phenotype and glucose intolerance in pregnancy. Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 182: E722-5. PMID 20855478 DOI: 10.1503/Cmaj.100378 |
0.562 |
|
| 2010 |
Gaudet D, de Wal J, Tremblay K, Déry S, van Deventer S, Freidig A, Brisson D, Méthot J. Review of the clinical development of alipogene tiparvovec gene therapy for lipoprotein lipase deficiency. Atherosclerosis. Supplements. 11: 55-60. PMID 20427244 DOI: 10.1016/J.Atherosclerosissup.2010.03.004 |
0.615 |
|
| 2010 |
Raal FJ, Santos RD, Blom DJ, Marais AD, Charng MJ, Cromwell WC, Lachmann RH, Gaudet D, Tan JL, Chasan-Taber S, Tribble DL, Flaim JD, Crooke ST. Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial. Lancet (London, England). 375: 998-1006. PMID 20227758 DOI: 10.1016/S0140-6736(10)60284-X |
0.395 |
|
| 2010 |
Pausova Z, Abrahamowicz M, Mahboubi A, Syme C, Leonard GT, Perron M, Richer L, Veillette S, Gaudet D, Paus T. Functional variation in the androgen-receptor gene is associated with visceral adiposity and blood pressure in male adolescents. Hypertension. 55: 706-14. PMID 20083725 DOI: 10.1161/Hypertensionaha.109.146720 |
0.305 |
|
| 2010 |
Dastani Z, Pajukanta P, Marcil M, Rudzicz N, Ruel I, Bailey SD, Lee JC, Lemire M, Faith J, Platko J, Rioux J, Hudson TJ, Gaudet D, Engert JC, Genest J. Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects. European Journal of Human Genetics : Ejhg. 18: 342-7. PMID 19844255 DOI: 10.1038/Ejhg.2009.157 |
0.381 |
|
| 2010 |
Gaudet D, de Wal J, Brisson D, van den Bulk N, Greentree S, Méthot J. L7 RESULTS OF FIRST FOLLOW UP STUDY WITH GENE THERAPY WITH ALIPOGENE TIPARVOVEC (AMT-011) IN LIPOPROTEIN LIPASE DEFICIENCY (LPLD) Atherosclerosis Supplements. 11: 15. DOI: 10.1016/S1567-5688(10)70067-2 |
0.596 |
|
| 2010 |
Cromwell WC, Santos RD, Blom DJ, Marais DA, Lachmann RH, Gaudet D, Tan JL, Chasan-Taber S, Tribble DL, Flaim J, Raal FJ, Charng M. Mipomersen, a First-in-Class Apolipoprotein B Synthesis Inhibitor, Lowers Lipoprotein (a) in Patients with Homozygous Familial Hypercholesterolemia Journal of Clinical Lipidology. 4: 221. DOI: 10.1016/J.Jacl.2010.03.055 |
0.322 |
|
| 2010 |
Gaudet D, Frisch F, Méthot J, Gagné C, Déry S, Tremblay K, de Wal J, Twisk J, Brisson D, Carpentier A. Gene Therapy With Alipogene Tiparvovec Results in Enhanced Post-prandial Clearance of Chylomicrons in LPLD Patients Atherosclerosis Supplements. 11: 74. DOI: 10.1016/J.Atherosclerosissup.2010.04.025 |
0.584 |
|
| 2010 |
Gaudet D, Methot J, Brisson D, Dery S, van den Bulk N, Greentree S, Gagné C. Alipogene Tiparvovec May Prevent Pancreatitis From Chylomicronaemia in Lipoprotein Lipase Deficiency (LPLD) Atherosclerosis Supplements. 11: 73-74. DOI: 10.1016/J.Atherosclerosissup.2010.04.024 |
0.581 |
|
| 2010 |
Greentree S, Gaudet D, Stroes E, van den Bulk N, de Wal J. Gene therapy with alipogene tiparvovec benefits lipoprotein lipase deficiency (LPLD) patients with pancreatitis history Atherosclerosis. 213: e4. DOI: 10.1016/J.Atherosclerosis.2010.07.039 |
0.346 |
|
| 2009 |
Pausova Z, Syme C, Abrahamowicz M, Xiao Y, Leonard GT, Perron M, Richer L, Veillette S, Smith GD, Seda O, Tremblay J, Hamet P, Gaudet D, Paus T. A common variant of the FTO gene is associated with not only increased adiposity but also elevated blood pressure in French Canadians. Circulation. Cardiovascular Genetics. 2: 260-9. PMID 20031594 DOI: 10.1161/Circgenetics.109.857359 |
0.323 |
|
| 2009 |
Villani AC, Lemire M, Louis E, Silverberg MS, Collette C, Fortin G, Nimmo ER, Renaud Y, Brunet S, Libioulle C, Belaiche J, Bitton A, Gaudet D, Cohen A, Langelier D, et al. Genetic variation in the familial Mediterranean fever gene (MEFV) and risk for Crohn's disease and ulcerative colitis. Plos One. 4: e7154. PMID 19784369 DOI: 10.1371/Journal.Pone.0007154 |
0.329 |
|
| 2009 |
Paglialunga S, Julien P, Tahiri Y, Cadelis F, Bergeron J, Gaudet D, Cianflone K. Lipoprotein lipase deficiency is associated with elevated acylation stimulating protein plasma levels. Journal of Lipid Research. 50: 1109-19. PMID 19237736 DOI: 10.1194/Jlr.M800430-Jlr200 |
0.342 |
|
| 2009 |
Do R, Kiss R, Gaudet D, Engert J. Squalene synthase: a critical enzyme in the cholesterol biosynthesis pathway. Clinical Genetics. 75: 19-29. PMID 19054015 DOI: 10.1111/J.1399-0004.2008.01099.X |
0.398 |
|
| 2009 |
Methot J, Bouhali T, Brisson D, Bouchard L, Tremblay G, Gaudet D. Abstract: P848 THE COMBINATION OF THE “HYPERTRIGLYCERIDEMIC WAIST” PHENOTYPE AND MENOPAUSE INCREASES CORONARY ARTERY DISEASE RISK AT A HIGHER LEVEL THAN DOES FAMILIAL HYPERCHOLESTEROLEMIA IN WOMEN Atherosclerosis Supplements. 10: e991. DOI: 10.1016/S1567-5688(09)70969-9 |
0.602 |
|
| 2009 |
van der Graaf A, Vissers M, Gaudet D, Brisson D, Sivapalaratnam S, Roseboom T, Janssen A, Kastelein J, Hutten B. Abstract: 1024 THE DYSLIPIDEMIA OF MOTHERS WITH FAMILIAL HYPERCHOLESTEROLEMIA DETERIORATES LIPID LEVELS IN THEIR ADULT OFFSPRING Atherosclerosis Supplements. 10: e391. DOI: 10.1016/S1567-5688(09)70383-6 |
0.595 |
|
| 2009 |
Methot J, Brisson D, Perron P, Gaudet D. Abstract: 1017 RELATION OF THE “HYPERTRIGLYCERIDEMIC WAIST” PHENOTYPE TO GLUCOSE INTOLERANCE AND TYPE 2 DIABETES IN POSTMENOPAUSAL WOMEN Atherosclerosis Supplements. 10: e388. DOI: 10.1016/S1567-5688(09)70380-0 |
0.555 |
|
| 2009 |
Gaudet D, Brisson D, Methot J, van Deventer S. Abstract: 554 AN OPEN-LABEL, DOSE ESCALATION STUDY TO ASSESS THE SAFETY AND EFFICACY OF AAV1-LPLS447X GENE THERAPY WITH ALIPOGENE TIPARVOVEC (AMT-011) FOR PATIENTS WITH SEVERE HYPERTRIGLYCERIDEMIA DUE TO LIPOPROTEIN LIPASE DEFICIENCY (LPLD) Atherosclerosis Supplements. 10: e286. DOI: 10.1016/S1567-5688(09)70286-7 |
0.587 |
|
| 2008 |
Kastelein JJ, Akdim F, Stroes ES, Zwinderman AH, Bots ML, Stalenhoef AF, Visseren FL, Sijbrands EJ, Trip MD, Stein EA, Gaudet D, Duivenvoorden R, Veltri EP, Marais AD, de Groot E, et al. Simvastatin with or without ezetimibe in familial hypercholesterolemia. The New England Journal of Medicine. 358: 1431-43. PMID 18376000 DOI: 10.1056/Nejmoa0800742 |
0.368 |
|
| 2008 |
Do R, Paré G, Montpetit A, Hudson TJ, Gaudet D, Engert JC. K45R variant of squalene synthase increases total cholesterol levels in two study samples from a French Canadian population. Human Mutation. 29: 689-94. PMID 18350552 DOI: 10.1002/Humu.20702 |
0.404 |
|
| 2008 |
Blackburn P, Lemieux I, Lamarche B, Bergeron J, Perron P, Tremblay G, Gaudet D, Després JP. Type 2 diabetes without the atherogenic metabolic triad does not predict angiographically assessed coronary artery disease in women. Diabetes Care. 31: 170-2. PMID 17934152 DOI: 10.2337/Dc07-0272 |
0.354 |
|
| 2008 |
Engert JC, Lemire M, Faith J, Brisson D, Fujiwara TM, Roslin NM, Brewer CG, Montpetit A, Darmond-Zwaig C, Renaud Y, Doré C, Bailey SD, Verner A, Tremblay G, St-Pierre J, ... ... Gaudet D, et al. Identification of a chromosome 8p locus for early-onset coronary heart disease in a French Canadian population. European Journal of Human Genetics : Ejhg. 16: 105-14. PMID 17805225 DOI: 10.1038/Sj.Ejhg.5201920 |
0.725 |
|
| 2008 |
Bouhali T, Brisson D, St-Pierre J, Tremblay G, Perron P, Laprise C, Vohl MC, Vissers MN, Hutten BA, Després JP, Kastelein JJ, Gaudet D. Low plasma adiponectin exacerbates the risk of premature coronary artery disease in familial hypercholesterolemia. Atherosclerosis. 196: 262-9. PMID 17123536 DOI: 10.1016/J.Atherosclerosis.2006.10.035 |
0.738 |
|
| 2007 |
Perron P, Brisson D, Santuré M, Blackburn P, Bergeron J, Vohl MC, Després JP, Gaudet D. Apolipoprotein E and lipoprotein lipase gene polymorphisms interaction on the atherogenic combined expression of hypertriglyceridemia and hyperapobetalipoproteinemia phenotypes. Journal of Endocrinological Investigation. 30: 551-7. PMID 17848837 DOI: 10.1007/Bf03346348 |
0.643 |
|
| 2007 |
Broeckel U, Hengstenberg C, Mayer B, Maresso K, Gaudet D, Seda O, Tremblay J, Holmer S, Erdmann J, Glöckner C, Harrison M, Martin LJ, Williams JT, Schmitz G, Riegger GA, et al. A locus on chromosome 10 influences C-reactive protein levels in two independent populations. Human Genetics. 122: 95-102. PMID 17530289 DOI: 10.1007/S00439-007-0380-9 |
0.326 |
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| 2007 |
Pare G, Serre D, Brisson D, Anand SS, Montpetit A, Tremblay G, Engert JC, Hudson TJ, Gaudet D. Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol. American Journal of Human Genetics. 80: 673-82. PMID 17357073 DOI: 10.1086/513286 |
0.645 |
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| 2007 |
Brisson D, St-Pierre J, Santuré M, Hudson TJ, Després JP, Vohl MC, Gaudet D. Genetic epistasis in the VLDL catabolic pathway is associated with deleterious variations on triglyceridemia in obese subjects. International Journal of Obesity (2005). 31: 1325-33. PMID 17342071 DOI: 10.1038/Sj.Ijo.0803586 |
0.612 |
|
| 2007 |
Winckler W, Weedon MN, Graham RR, McCarroll SA, Purcell S, Almgren P, Tuomi T, Gaudet D, Boström KB, Walker M, Hitman G, Hattersley AT, McCarthy MI, Ardlie KG, Hirschhorn JN, et al. Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes. Diabetes. 56: 685-93. PMID 17327436 DOI: 10.2337/Db06-0202 |
0.329 |
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| 2007 |
Campbell CD, Lyon HN, Nemesh J, Drake JA, Tuomi T, Gaudet D, Zhu X, Cooper RS, Ardlie KG, Groop LC, Hirschhorn JN. Association studies of BMI and type 2 diabetes in the neuropeptide Y pathway: a possible role for NPY2R as a candidate gene for type 2 diabetes in men. Diabetes. 56: 1460-7. PMID 17325259 DOI: 10.2337/Db06-1051 |
0.312 |
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| 2007 |
St-Pierre J, Lemieux I, Perron P, Brisson D, Santuré M, Vohl MC, Després JP, Gaudet D. Relation of the "hypertriglyceridemic waist" phenotype to earlier manifestations of coronary artery disease in patients with glucose intolerance and type 2 diabetes mellitus. The American Journal of Cardiology. 99: 369-73. PMID 17261400 DOI: 10.1016/J.Amjcard.2006.08.041 |
0.726 |
|
| 2007 |
Robitaille J, Houde A, Lemieux S, Gaudet D, Pérusse L, Vohl MC. The lipoprotein/lipid profile is modulated by a gene-diet interaction effect between polymorphisms in the liver X receptor-alpha and dietary cholesterol intake in French-Canadians. The British Journal of Nutrition. 97: 11-8. PMID 17217555 DOI: 10.1017/S0007114507201722 |
0.357 |
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| 2007 |
Robitaille J, Houde A, Lemieux S, Pérusse L, Gaudet D, Vohl MC. Variants within the muscle and liver isoforms of the carnitine palmitoyltransferase I (CPT1) gene interact with fat intake to modulate indices of obesity in French-Canadians. Journal of Molecular Medicine (Berlin, Germany). 85: 129-37. PMID 17089095 DOI: 10.1007/S00109-006-0116-7 |
0.307 |
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| 2007 |
Hogue JC, Lamarche B, Gaudet D, Tremblay AJ, Després JP, Bergeron J, Gagné C, Couture P. Association of heterozygous familial hypercholesterolemia with smaller HDL particle size. Atherosclerosis. 190: 429-35. PMID 16546193 DOI: 10.1016/J.Atherosclerosis.2006.02.023 |
0.352 |
|
| 2007 |
Raal FJ, Marais AD, Gagne C, Gaudet D, Viljoen J, Hemphill L, Durham K, Thuren T, Shear C. Po23-764 Torcetrapib/Atorvastatin Substantially Raises Hdl-C And Markedly Lowers Ldl-C In Patients With Homozygous Familial Hypercholesterolemia Atherosclerosis Supplements. 8: 204. DOI: 10.1016/S1567-5688(07)71774-9 |
0.334 |
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| 2006 |
Florez JC, Saxena R, Winckler W, Burtt NP, Almgren P, Bengtsson Boström K, Tuomi T, Gaudet D, Ardlie KG, Daly MJ, Altshuler D, Hirschhorn JN, Groop L. The Krüppel-like factor 11 (KLF11) Q62R polymorphism is not associated with type 2 diabetes in 8,676 people. Diabetes. 55: 3620-4. PMID 17130512 DOI: 10.2337/Db06-0867 |
0.312 |
|
| 2006 |
Bailey SD, Loredo-Osti JC, Lepage P, Faith J, Fontaine J, Desbiens KM, Hudson TJ, Bouchard C, Gaudet D, Pérusse L, Vohl MC, Engert JC. Common polymorphisms in the promoter of the visfatin gene (PBEF1) influence plasma insulin levels in a French-Canadian population Diabetes. 55: 2896-2902. PMID 17003359 DOI: 10.2337/Db06-0189 |
0.316 |
|
| 2006 |
Saxena R, de Bakker PI, Singer K, Mootha V, Burtt N, Hirschhorn JN, Gaudet D, Isomaa B, Daly MJ, Groop L, Ardlie KG, Altshuler D. Comprehensive association testing of common mitochondrial DNA variation in metabolic disease. American Journal of Human Genetics. 79: 54-61. PMID 16773565 DOI: 10.1086/504926 |
0.316 |
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| 2006 |
Sun MW, Lee JY, de Bakker PI, Burtt NP, Almgren P, RÃ¥stam L, Tuomi T, Gaudet D, Daly MJ, Hirschhorn JN, Altshuler D, Groop L, Florez JC. Haplotype structures and large-scale association testing of the 5' AMP-activated protein kinase genes PRKAA2, PRKAB1, and PRKAB2 [corrected] with type 2 diabetes. Diabetes. 55: 849-55. PMID 16505254 DOI: 10.2337/Diabetes.55.03.06.Db05-1418 |
0.332 |
|
| 2006 |
Florez JC, Wiltshire S, Agapakis CM, Burtt NP, de Bakker PI, Almgren P, Bengtsson Boström K, Tuomi T, Gaudet D, Daly MJ, Hirschhorn JN, McCarthy MI, Altshuler D, Groop L. High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people. Diabetes. 55: 128-35. PMID 16380485 DOI: 10.2337/Diabetes.55.01.06.Db05-0954 |
0.314 |
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| 2006 |
Hogue JC, Lamarche B, Gaudet D, Tremblay AJ, Després JP, Gagné C, Couture P. Genotype of the mutant LDL receptor allele is associated with LDL particle size heterogeneity in familial hypercholesterolemia. Atherosclerosis. 184: 163-70. PMID 15899484 DOI: 10.1016/J.Atherosclerosis.2005.03.027 |
0.341 |
|
| 2006 |
Bouhali T, Brisson D, Tremblay G, Perron P, Vohl M, Despres J, Vissers M, Hutten B, Kastelein J, Gaudet D. Th-W58:6 Combined effect of adiponectin and HDL-cholesterol on premature coronary artery disease risk in familial hypercholesterolemia and other dyslipidemias Atherosclerosis Supplements. 7: 484. DOI: 10.1016/S1567-5688(06)81934-3 |
0.625 |
|
| 2006 |
Blackburn P, Lemieux I, Lamarche B, Bergeron J, Perron P, Tremblay G, Gaudet D, Després J. Th-W54:4 Risk of angiographically-assessed coronary artery disease associated with LDL and HDL particle sizes in women Atherosclerosis Supplements. 7: 475. DOI: 10.1016/S1567-5688(06)81903-3 |
0.313 |
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| 2006 |
Perron P, Brisson D, Santure M, Blackburn P, Despres J, Gaudet D. We-W30:5 Epistatic effect of frequent apolipoprotein E and lipoprotein lipase gene variants on hypertrigly ceridemia hyperapobetalipoproteinemia expression Atherosclerosis Supplements. 7: 306. DOI: 10.1016/S1567-5688(06)81230-4 |
0.605 |
|
| 2006 |
Santure M, Brisson D, Tremblay G, Lamarche B, Gaudet D. Tu-W27:6 Relationship between triglyceride-enriched HDL particles and intolerance to statin therapy Atherosclerosis Supplements. 7: 175. DOI: 10.1016/S1567-5688(06)80681-1 |
0.584 |
|
| 2006 |
Engert J, Pare G, Lemire M, Faith J, Brisson D, Vohl M, Tremblay G, Hudson T, Gaudet D. Mo-P6:391 Identification of a chromosome 8P locus for coronary heart disease in the French Canadian founder population Atherosclerosis Supplements. 7: 131-132. DOI: 10.1016/S1567-5688(06)80521-0 |
0.561 |
|
| 2005 |
Pausova Z, Gaudet D, Gossard F, Bernard M, Kaldunski ML, Jomphe M, Tremblay J, Hudson TJ, Bouchard G, Kotchen TA, Cowley AW, Hamet P. Genome-wide scan for linkage to obesity-associated hypertension in French Canadians. Hypertension. 46: 1280-5. PMID 16216983 DOI: 10.1161/01.Hyp.0000188049.23233.Fb |
0.328 |
|
| 2005 |
Winckler W, Burtt NP, Holmkvist J, Cervin C, de Bakker PI, Sun M, Almgren P, Tuomi T, Gaudet D, Hudson TJ, Ardlie KG, Daly MJ, Hirschhorn JN, Altshuler D, Groop L. Association of common variation in the HNF1alpha gene region with risk of type 2 diabetes. Diabetes. 54: 2336-42. PMID 16046299 DOI: 10.2337/Diabetes.54.8.2336 |
0.308 |
|
| 2005 |
Hamet P, Merlo E, Seda O, Broeckel U, Tremblay J, Kaldunski M, Gaudet D, Bouchard G, Deslauriers B, Gagnon F, Antoniol G, Pausová Z, Labuda M, Jomphe M, Gossard F, et al. Quantitative founder-effect analysis of French Canadian families identifies specific loci contributing to metabolic phenotypes of hypertension. American Journal of Human Genetics. 76: 815-32. PMID 15800845 DOI: 10.1086/430133 |
0.338 |
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| 2005 |
Brisson D, Mathieu J, Vohl MC, Gaudet D. Presence of palmar xanthomas in myotonic dystrophy identifies different patterns of linkage disequilibrium between the apolipoprotein E and myotonic dystrophy protein kinase loci. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 7: 213-5. PMID 15775763 DOI: 10.1097/01.Gim.0000157130.81975.Fe |
0.547 |
|
| 2005 |
Winckler W, Graham RR, de Bakker PI, Sun M, Almgren P, Tuomi T, Gaudet D, Hudson TJ, Ardlie KG, Daly MJ, Hirschhorn JN, Groop L, Altshuler D. Association testing of variants in the hepatocyte nuclear factor 4alpha gene with risk of type 2 diabetes in 7,883 people. Diabetes. 54: 886-92. PMID 15734869 DOI: 10.2337/Diabetes.54.3.886 |
0.302 |
|
| 2005 |
St-Pierre J, Vohl MC, Després JP, Gaudet D, Poirier P. Genetic aspects of diabetes and its cardiovascular complications: Contribution of genetics to risk assessment and clinical management Canadian Journal of Cardiology. 21: 199-209. PMID 15729423 |
0.598 |
|
| 2005 |
Berthier MT, Houde A, Côté M, Paradis AM, Mauriège P, Bergeron J, Gaudet D, Després JP, Vohl MC. Impact of adiponectin gene polymorphisms on plasma lipoprotein and adiponectin concentrations of viscerally obese men. Journal of Lipid Research. 46: 237-44. PMID 15547300 DOI: 10.1194/Jlr.M400135-Jlr200 |
0.356 |
|
| 2005 |
Robitaille J, Brouillette C, Lemieux S, Pérusse L, Gaudet D, Vohl MC. Plasma concentrations of apolipoprotein B are modulated by a gene--diet interaction effect between the LFABP T94A polymorphism and dietary fat intake in French-Canadian men. Molecular Genetics and Metabolism. 82: 296-303. PMID 15308127 DOI: 10.1016/J.Ymgme.2004.06.002 |
0.309 |
|
| 2005 |
Bouhali T, Brisson D, Tremblay G, Gagne C, Couture P, Vissers M, Hutten B, Kastelein J, Gaudet D. W08-O-001 Familial hypercholesterolemia patients with coronary artery disease Atherosclerosis Supplements. 6: 29. DOI: 10.1016/S1567-5688(05)80114-X |
0.579 |
|
| 2004 |
Berthier MT, Houde A, Paradis AM, Couture P, Gaudet D, Després JP, Vohl MC. Molecular screening of the microsomal triglyceride transfer protein: association between polymorphisms and both abdominal obesity and plasma apolipoprotein B concentration. Journal of Human Genetics. 49: 684-90. PMID 15635487 DOI: 10.1007/S10038-004-0207-7 |
0.36 |
|
| 2004 |
Blackburn P, Lemieux I, Lamarche B, Bergeron J, Perron P, Tremblay G, Gaudet D, Després JP. Effect of type 2 diabetes on various electrophoretic characteristics of low-density lipoprotein particles in women. Diabetologia. 47: 2114-7. PMID 15602652 DOI: 10.1007/S00125-004-1585-2 |
0.316 |
|
| 2004 |
Robitaille J, Brouillette C, Houde A, Lemieux S, Pérusse L, Tchernof A, Gaudet D, Vohl MC. Association between the PPARalpha-L162V polymorphism and components of the metabolic syndrome. Journal of Human Genetics. 49: 482-9. PMID 15309680 DOI: 10.1007/S10038-004-0177-9 |
0.351 |
|
| 2004 |
Brouillette C, Bossé Y, Pérusse L, Gaudet D, Vohl MC. Effect of liver fatty acid binding protein (FABP) T94A missense mutation on plasma lipoprotein responsiveness to treatment with fenofibrate. Journal of Human Genetics. 49: 424-32. PMID 15249972 DOI: 10.1007/S10038-004-0171-2 |
0.381 |
|
| 2004 |
Florez JC, Burtt N, de Bakker PI, Almgren P, Tuomi T, Holmkvist J, Gaudet D, Hudson TJ, Schaffner SF, Daly MJ, Hirschhorn JN, Groop L, Altshuler D. Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region. Diabetes. 53: 1360-8. PMID 15111507 DOI: 10.2337/Diabetes.53.5.1360 |
0.341 |
|
| 2004 |
Hogue JC, Lamarche B, Gaudet D, Larivière M, Tremblay AJ, Bergeron J, Lemieux I, Després JP, Gagné C, Couture P. Relationship between cholesteryl ester transfer protein and LDL heterogeneity in familial hypercholesterolemia. Journal of Lipid Research. 45: 1077-83. PMID 15026427 DOI: 10.1194/Jlr.M300420-Jlr200 |
0.35 |
|
| 2004 |
Berthier MT, Couture P, Houde A, Paradis AM, Sammak A, Verner A, Deprés JP, Gagné C, Gaudet D, Vohl MC. The c.419-420insA in the MTP gene is associated with abetalipoproteinemia among French-Canadians. Molecular Genetics and Metabolism. 81: 140-3. PMID 14741197 DOI: 10.1016/J.Ymgme.2003.11.001 |
0.345 |
|
| 2003 |
Ruel IL, Gaudet D, Perron P, Bergeron J, Julien P, Lamarche B. Effect of obesity on HDL and LDL particle sizes in carriers of the null P207L or defective D9N mutation in the lipoprotein lipase gene: the Québec LipD Study. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity. 27: 631-7. PMID 12704407 DOI: 10.1038/Sj.Ijo.0802276 |
0.367 |
|
| 2003 |
Pausova Z, Sedova L, Berube J, Hamet P, Tremblay J, Dumont M, Gaudet D, Pravenec M, Kren V, Kunes J. Segment of rat chromosome 20 regulates diet-induced augmentations in adiposity, glucose intolerance, and blood pressure. Hypertension. 41: 1047-55. PMID 12654711 DOI: 10.1161/01.Hyp.0000064347.49341.0B |
0.311 |
|
| 2003 |
St-Pierre J, Miller-Felix I, Paradis ME, Bergeron J, Lamarche B, Després JP, Gaudet D, Vohl MC. Visceral obesity attenuates the effect of the hepatic lipase -514C>T polymorphism on plasma HDL-cholesterol levels in French-Canadian men. Molecular Genetics and Metabolism. 78: 31-6. PMID 12559845 DOI: 10.1016/S1096-7192(02)00223-8 |
0.639 |
|
| 2003 |
Gaudet D, Vohl M, Brisson D, Connely P, Hamet P, Hudson T, Laberge C, Laprise C. 2P-0353 Prevalence and geographic distribution of a frequent genotypic combination of hyperapo B in the Quebec population Atherosclerosis Supplements. 4: 116. DOI: 10.1016/S1567-5688(03)90496-X |
0.542 |
|
| 2003 |
Gaudet D, Perron P, Saint-Pierre J, Brisson D, Russe L, Bergeron J, Rioux J, Vohl M, Hudson T. 2HT01-3 Glycerolemia and glucose intolerance prediction: Illustration of the application of genomic research to medical practice Atherosclerosis Supplements. 4: 105. DOI: 10.1016/S1567-5688(03)90453-3 |
0.524 |
|
| 2003 |
Laberge L, Armstrong L, Brisson D, Lacroix G, Perron P, Gaudet D. 1P-0124 Relationship between sustained attention and metabolic parameters in a monogenic model of susceptibility to type 2 diabetes Atherosclerosis Supplements. 4: 47. DOI: 10.1016/S1567-5688(03)90199-1 |
0.559 |
|
| 2002 |
St-Pierre J, Lemieux I, Vohl MC, Perron P, Tremblay G, Després JP, Gaudet D. Contribution of abdominal obesity and hypertriglyceridemia to impaired fasting glucose and coronary artery disease. The American Journal of Cardiology. 90: 15-8. PMID 12088772 DOI: 10.1016/S0002-9149(02)02378-0 |
0.62 |
|
| 2002 |
Pausova Z, Jomphe M, Houde L, Vezina H, Orlov SN, Gossard F, Gaudet D, Tremblay J, Kotchen TA, Cowley AW, Bouchard G, Hamet P. A genealogical study of essential hypertension with and without obesity in French Canadians. Obesity Research. 10: 463-70. PMID 12055322 DOI: 10.1038/Oby.2002.64 |
0.325 |
|
| 2002 |
Brisson D, Ledoux K, Bossé Y, St-Pierre J, Julien P, Perron P, Hudson TJ, Vohl MC, Gaudet D. Effect of apolipoprotein E, peroxisome proliferator-activated receptor alpha and lipoprotein lipase gene mutations on the ability of fenofibrate to improve lipid profiles and reach clinical guideline targets among hypertriglyceridemic patients. Pharmacogenetics. 12: 313-20. PMID 12042669 DOI: 10.1097/00008571-200206000-00007 |
0.748 |
|
| 2002 |
Gagné C, Gaudet D, Bruckert E. Efficacy and safety of ezetimibe coadministered with atorvastatin or simvastatin in patients with homozygous familial hypercholesterolemia. Circulation. 105: 2469-75. PMID 12034651 DOI: 10.1161/01.Cir.0000018744.58460.62 |
0.33 |
|
| 2002 |
Ruel IL, Gaudet D, Perron P, Pascot A, Després JP, Bergeron J, Julien P, Lamarche B. Determinants of HDL particle size in patients with the null (P207L) or defective (D9N) mutation in the lipoprotein lipase gene: the Québec LipD Study. Atherosclerosis. 162: 269-76. PMID 11996946 DOI: 10.1016/S0021-9150(01)00716-X |
0.337 |
|
| 2002 |
Engert JC, Vohl MC, Williams SM, Lepage P, Loredo-Osti JC, Faith J, Doré C, Renaud Y, Burtt NP, Villeneuve A, Hirschhorn JN, Altshuler D, Groop LC, Després JP, Gaudet D, et al. 5' flanking variants of resistin are associated with obesity. Diabetes. 51: 1629-34. PMID 11978666 DOI: 10.2337/Diabetes.51.5.1629 |
0.315 |
|
| 2002 |
St-Pierre J, Lemieux I, Miller-Felix I, Prud'homme D, Bergeron J, Gaudet D, Nadeau A, Despres JP, Vohl MC. Visceral obesity and hyperinsulinemia modulate the impact of the microsomal triglyceride transfer protein -493G/T polymorphism on plasma lipoprotein levels in men. Atherosclerosis. 160: 317-24. PMID 11849654 DOI: 10.1016/S0021-9150(01)00589-5 |
0.638 |
|
| 2002 |
Brisson D, Houde G, St-Pierre J, Vohl M, Mathieu J, Gaudet D. The pleiotropic expression of the myotonic dystrophy protein kinase gene illustrates the complex relationships between genetic, biological and clinical covariates of male aging The Aging Male. 5: 223-232. DOI: 10.1080/Tam.5.4.223.232 |
0.719 |
|
| 2002 |
Gagne C, Gaudet D, Bruckert E, Ponsonnet D, Lipka L, LeBeaut A, Suresh R, Abreu P, Veltri E. Ezetimibe significantly reduces low-density lipoprotein cholesterol in homozygous familial hypercholesterolemia Journal of the American College of Cardiology. 39: 227. DOI: 10.1016/S0735-1097(02)81012-9 |
0.371 |
|
| 2001 |
Brisson D, Vohl MC, St-Pierre J, Hudson TJ, Gaudet D. Glycerol: a neglected variable in metabolic processes? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 23: 534-42. PMID 11385633 DOI: 10.1002/Bies.1073 |
0.694 |
|
| 2001 |
St-Pierre J, Vohl MC, Brisson D, Perron P, Després JP, Hudson TJ, Gaudet D. A sequence variation in the mitochondrial glycerol-3-phosphate dehydrogenase gene is associated with increased plasma glycerol and free fatty acid concentrations among French Canadians. Molecular Genetics and Metabolism. 72: 209-17. PMID 11243726 DOI: 10.1006/Mgme.2000.3144 |
0.721 |
|
| 2000 |
Altshuler D, Hirschhorn JN, Klannemark M, Lindgren CM, Vohl MC, Nemesh J, Lane CR, Schaffner SF, Bolk S, Brewer C, Tuomi T, Gaudet D, Hudson TJ, Daly M, Groop L, et al. The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nature Genetics. 26: 76-80. PMID 10973253 DOI: 10.1038/79216 |
0.306 |
|
| 2000 |
Lemieux I, Pascot A, Couillard C, Lamarche B, Tchernof A, Alméras N, Bergeron J, Gaudet D, Tremblay G, Prud'homme D, Nadeau A, Després JP. Hypertriglyceridemic waist: A marker of the atherogenic metabolic triad (hyperinsulinemia; hyperapolipoprotein B; small, dense LDL) in men? Circulation. 102: 179-84. PMID 10889128 DOI: 10.1161/01.Cir.102.2.179 |
0.338 |
|
| 2000 |
Gaudet D, Arsenault S, Pérusse L, Vohl MC, St-Pierre J, Bergeron J, Després JP, Dewar K, Daly MJ, Hudson T, Rioux JD. Glycerol as a correlate of impaired glucose tolerance: dissection of a complex system by use of a simple genetic trait. American Journal of Human Genetics. 66: 1558-68. PMID 10736265 DOI: 10.1086/302903 |
0.383 |
|
| 2000 |
Gossard F, Pausova Z, Deslauriers B, Kotchen TA, Cowley AW, Gaudet D, Tremblay J, Hamet P. Heritability of Heart Rate upon Stimulation in Members of Families with History of Hypertension Hypertension. 36: 718-718. DOI: 10.1161/01.Hyp.36.Suppl_1.718-B |
0.317 |
|
| 2000 |
Vigneault A, Brisson D, Bélanger C, Gaudet D. Community genetics in Eastern Québec: The experience of the Corporation for Research and Action on Hereditary Diseases Community Genetics. 3: 151-155. DOI: 10.1159/000051128 |
0.556 |
|
| 2000 |
Bergeron J, Julien P, Gaudet D, Julien E, Cadelis F, Gagné C, Murthy M. SstI polymorphism of the apo C3 gene and expression of dysbetalipoproteinemia (type III) in individuals heterozygous for familial LPL deficiency Atherosclerosis. 151: 312. DOI: 10.1016/S0021-9150(00)81420-3 |
0.336 |
|
| 2000 |
Julien P, Gaudet D, Bergeron J, Xu K, Cadelis F, Luo X, Murthy M. Apo e2 allele is a modulator of dysbetalipoproteinemia (type III) expression in individuals heterozygous for familial lipoprotein lipase deficiency Atherosclerosis. 151: 268-269. DOI: 10.1016/S0021-9150(00)81215-0 |
0.322 |
|
| 2000 |
Julien P, Bergeron J, Gaudet D, Cadelis F, Perron P. Impact of body mass index on the expression of hypertriglyceridemia in familial lipoprotein lipase (LPL) deficiency is related to the type of LPL gene mutation Atherosclerosis. 151: 100. DOI: 10.1016/S0021-9150(00)80452-9 |
0.331 |
|
| 2000 |
Lamarche B, St-Pierre A, Julien P, Bergeron J, Perron P, Gaudet D. Efficacy of pravastatin in reducing plasma LDL-cholesterol and LDL-apo B concentrations in mixed hyperlipidemias of different genetic causes Atherosclerosis. 151: 48. DOI: 10.1016/S0021-9150(00)80215-4 |
0.346 |
|
| 2000 |
St-Pierre J, Lemieux I, Perron P, Tremblay G, Després J, Gaudet D. Fasting dysglycemia and coronary artery disease: Contribution of abdominal obesity and hypertriglyceridemia Atherosclerosis. 151: 17. DOI: 10.1016/S0021-9150(00)80073-8 |
0.591 |
|
| 1999 |
Gaudet D, Gagné C, Perron P, Couture P, Tonstad S. Ethical issues in molecular screening for heterozygous familial hypercholesterolemia: the complexity of dealing with genetic susceptibility to coronary artery disease. Community Genetics. 2: 2-8. PMID 11658106 DOI: 10.1159/000016176 |
0.36 |
|
| 1999 |
Gaudet D, Vohl MC, Couture P, Moorjani S, Tremblay G, Perron P, Gagné C, Després JP. Contribution of receptor negative versus receptor defective mutations in the LDL-receptor gene to angiographically assessed coronary artery disease among young (25-49 years) versus middle-aged (50-64 years) men. Atherosclerosis. 143: 153-61. PMID 10208490 DOI: 10.1016/S0021-9150(98)00268-8 |
0.355 |
|
| 1999 |
Couture P, Morissette J, Gaudet D, Vohl MC, Gagné C, Bergeron J, Després JP, Simard J. Fine mapping of low-density lipoprotein receptor gene by genetic linkage on chromosome 19p13.1-p13.3 and study of the founder effect of four French Canadian low-density lipoprotein receptor gene mutations. Atherosclerosis. 143: 145-51. PMID 10208489 DOI: 10.1016/S0021-9150(98)00267-6 |
0.377 |
|
| 1999 |
Couture P, Vohl MC, Gagné C, Gaudet D, Torres AL, Lupien PJ, Després JP, Labrie F, Simard J, Moorjani S. Identification of three mutations in the low-density lipoprotein receptor gene causing familial hypercholesterolemia among French Canadians. Human Mutation. S226-31. PMID 9452094 DOI: 10.1002/Humu.1380110173 |
0.35 |
|
| 1998 |
Gaudet D, Vohl MC, Julien P, Tremblay G, Perron P, Gagné C, Bergeron J, Moorjani S, Després JP. Relative contribution of low-density lipoprotein receptor and lipoprotein lipase gene mutations to angiographically assessed coronary artery disease among French Canadians. The American Journal of Cardiology. 82: 299-305. PMID 9708657 DOI: 10.1016/S0002-9149(98)00328-2 |
0.396 |
|
| 1998 |
Couture P, Brun LD, Szots F, Lelièvre M, Gaudet D, Després JP, Simard J, Lupien PJ, Gagné C. Association of specific LDL receptor gene mutations with differential plasma lipoprotein response to simvastatin in young French Canadians with heterozygous familial hypercholesterolemia. Arteriosclerosis, Thrombosis, and Vascular Biology. 18: 1007-12. PMID 9633944 DOI: 10.1161/01.Atv.18.6.1007 |
0.394 |
|
| 1998 |
Gaudet D, Vohl MC, Perron P, Tremblay G, Gagné C, Lesiège D, Bergeron J, Moorjani S, Després JP. Relationships of abdominal obesity and hyperinsulinemia to angiographically assessed coronary artery disease in men with known mutations in the LDL receptor gene. Circulation. 97: 871-7. PMID 9521335 DOI: 10.1161/01.Cir.97.9.871 |
0.377 |
|
| 1997 |
Julien P, Vohl MC, Gaudet D, Gagné C, Lévesque G, Després JP, Cadelis F, Brun LD, Nadeau A, Murthy MRV. Hyperinsulinemia and abdominal obesity affect the expression of hypertriglyceridemia in heterozygous familial lipoprotein lipase deficiency Diabetes. 46: 2063-2068. PMID 9392497 DOI: 10.2337/Diab.46.12.2063 |
0.407 |
|
| 1997 |
Julien P, Vohl M, Gaudet D, Gagné C, Lévesque G, Després J, Cadelis F, Brun L, Nadeau A, Murthy M. 4.P.114 Hyperinsulinemia and abdominal obesity in heterozygous familial lipoprotein lipase deficiency Atherosclerosis. 134: 320. DOI: 10.1016/S0021-9150(97)89644-X |
0.321 |
|
| 1997 |
Gaudet D, Couture P, Tremblay G, Brun D, Perron P, Bergeron J, Gagné C. 2.P.35 Lipid-lowering effect of atorvastatin in homozygous familial hypercholesterolemia patients with portocaval anastomosis Atherosclerosis. 134: 124. DOI: 10.1016/S0021-9150(97)88675-3 |
0.343 |
|
| 1997 |
Gaudet D, Vohl M, Julien P, Tremblay G, Perron P, Gagné C, Bergeron J, Després J. 1.P.288 Relative contribution of LDL-receptor and LPL gene mutations to angiographically assessed coronary artery disease among French Canadians Atherosclerosis. 134: 77. DOI: 10.1016/S0021-9150(97)88466-3 |
0.322 |
|
| 1997 |
Couture O, Morissette J, Gaudet D, Vohl M, Gagné C, Bergeron J, Després J, Simard J. 1.P.233 Molecular evidence of founder effect for four mutations in the low-density lipoprotein receptor gene in French Canadians with familial hypercholesterolemia Atherosclerosis. 134: 66. DOI: 10.1016/S0021-9150(97)88413-4 |
0.348 |
|
| 1997 |
Couture P, Gaudet D, Brun D, Bergeron J, Cantin L, Black D, Gagné C. 1.P.178 Effect of atorvastatin on serum levels of lipoproteins in French Canadians with homozygous or compound heterozygous familial hypercholesterolemia Atherosclerosis. 134: 54. DOI: 10.1016/S0021-9150(97)88357-8 |
0.322 |
|
| 1995 |
Pimstone SN, Gagné SE, Gagné C, Lupien PJ, Gaudet D, Williams RR, Kotze M, Reymer PW, Defesche JC, Kastelein JJ. Mutations in the gene for lipoprotein lipase. A cause for low HDL cholesterol levels in individuals heterozygous for familial hypercholesterolemia. Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 1704-12. PMID 7583547 DOI: 10.1161/01.Atv.15.10.1704 |
0.417 |
|
| 1995 |
Julien P, Vohl M, Lévesque G, Després J, Murthy M, Gagné C, Gaudet D, Brun D, Cadelis F, Moorjani S, Lupien P. Effect of obesity on plasma triglyceride levels in familial lipoprotein lipase deficiency Atherosclerosis. 115: S8. DOI: 10.1016/0021-9150(95)96283-X |
0.343 |
|
| 1994 |
Gaudet D, Moorjani S, Tremblay G, Perron P, Gagne´ C, Lupien P. Is there sexual dimorphism for coronary artery disease in homozygous familial hypercholesterolemia? Evidence from a kindred of a 60-year-old woman homozygous for W66G mutation in the LDL-receptor gene Atherosclerosis. 109: 131-132. DOI: 10.1016/0021-9150(94)93536-X |
0.322 |
|
| 1989 |
Thibault MC, Mathieu J, Moorjani S, Lescault A, Prévost C, Gaudet D, Morissette J, Laberge C. Myotonic dystrophy: linkage with apolipoprotein E and estimation of the gene carrier status with genetic markers. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 16: 134-40. PMID 2924208 DOI: 10.1017/S0317167100028687 |
0.361 |
|
| 1989 |
Moorjani S, Gaudet D, Laberge C, Thibault MC, Mathieu J, Morissette J, Lupien PJ, Brun D, Gagné C. Hypertriglyceridemia and lower LDL cholesterol concentration in relation to apolipoprotein E phenotypes in myotonic dystrophy. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 16: 129-33. PMID 2924207 DOI: 10.1017/S0317167100028675 |
0.34 |
|
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