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Donald C. Lo - Publications

Affiliations: 
Duke University, Durham, NC 
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54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Lee HK, Koh S, Lo DC, Marchuk DA. Neuronal IL-4Rα modulates neuronal apoptosis and cell viability during the acute phases of cerebral ischemia. The Febs Journal. PMID 29756681 DOI: 10.1111/febs.14498  0.304
2017 Dickey AS, Sanchez DN, Arreola M, Sampat KR, Fan W, Arbez N, Akimov S, Van Kanegan MJ, Ohnishi K, Gilmore-Hall SK, Flores AL, Nguyen JM, Lomas N, Hsu CL, Lo DC, et al. PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis. Science Translational Medicine. 9. PMID 29212711 DOI: 10.1126/Scitranslmed.Aal2332  0.341
2017 Khoshnan A, Sabbaugh A, Calamini B, Marinero SA, Dunn DE, Yoo JH, Ko J, Lo DC, Patterson PH. IKKβ and mutant huntingtin interactions regulate the expression of IL-34; implications for microglial-mediated neurodegeneration in HD. Human Molecular Genetics. PMID 28973132 DOI: 10.1093/Hmg/Ddx315  0.762
2017 Quinti L, Dayalan Naidu S, Träger U, Chen X, Kegel-Gleason K, Llères D, Connolly C, Chopra V, Low C, Moniot S, Sapp E, Tousley AR, Vodicka P, Van Kanegan MJ, Kaltenbach LS, ... ... Lo DC, et al. KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients. Proceedings of the National Academy of Sciences of the United States of America. PMID 28533375 DOI: 10.1073/Pnas.1614943114  0.312
2017 Gomez-Pastor R, Burchfiel ET, Neef DW, Jaeger AM, Cabiscol E, McKinstry SU, Doss A, Aballay A, Lo DC, Akimov SS, Ross CA, Eroglu C, Thiele DJ. Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease. Nature Communications. 8: 14405. PMID 28194040 DOI: 10.1038/Ncomms14405  0.369
2016 Shen K, Calamini B, Fauerbach JA, Ma B, Shahmoradian SH, Serrano Lachapel IL, Chiu W, Lo DC, Frydman J. Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract. Elife. 5. PMID 27751235 DOI: 10.7554/Elife.18065  0.334
2016 Quinti L, Casale M, Moniot S, Pais TF, Van Kanegan MJ, Kaltenbach LS, Pallos J, Lim RG, Naidu SD, Runne H, Meisel L, Rauf NA, Leyfer D, Maxwell MM, Saiah E, ... ... Lo DC, et al. SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models. Cell Chemical Biology. PMID 27427231 DOI: 10.1016/J.Chembiol.2016.05.015  0.346
2016 Lee HK, Keum S, Sheng H, Warner DS, Lo DC, Marchuk DA. Natural allelic variation of the IL-21 receptor modulates ischemic stroke infarct volume. The Journal of Clinical Investigation. PMID 27400126 DOI: 10.1172/Jci84491  0.311
2016 Van Kanegan MJ, Dunn DE, Kaltenbach LS, Shah B, He DN, McCoy DD, Yang P, Peng J, Shen L, Du L, Cichewicz RH, Newman RA, Lo DC. Dual activities of the anti-cancer drug candidate PBI-05204 provide neuroprotection in brain slice models for neurodegenerative diseases and stroke. Scientific Reports. 6: 25626. PMID 27172999 DOI: 10.1038/Srep25626  0.308
2016 Shen K, Calamini B, Fauerbach JA, Ma B, Shahmoradian SH, Lachapel ILS, Chiu W, Lo DC, Frydman J. Author response: Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract Elife. DOI: 10.7554/Elife.18065.024  0.301
2015 Christianson MG, Lo DC. Differential roles of Aβ processing in hypoxia-induced axonal damage. Neurobiology of Disease. 77: 94-105. PMID 25771168 DOI: 10.1016/J.Nbd.2015.02.027  0.737
2014 Van Kanegan MJ, He DN, Dunn DE, Yang P, Newman RA, West AE, Lo DC. BDNF mediates neuroprotection against oxygen-glucose deprivation by the cardiac glycoside oleandrin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 963-8. PMID 24431454 DOI: 10.1523/JNEUROSCI.2700-13.2014  0.304
2013 Marco S, Giralt A, Petrovic MM, Pouladi MA, Martínez-Turrillas R, Martínez-Hernández J, Kaltenbach LS, Torres-Peraza J, Graham RK, Watanabe M, Luján R, Nakanishi N, Lipton SA, Lo DC, Hayden MR, et al. Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models. Nature Medicine. 19: 1030-8. PMID 23852340 DOI: 10.1038/Nm.3246  0.781
2012 Baldo B, Paganetti P, Grueninger S, Marcellin D, Kaltenbach LS, Lo DC, Semmelroth M, Zivanovic A, Abramowski D, Smith D, Lotz GP, Bates GP, Weiss A. TR-FRET-based duplex immunoassay reveals an inverse correlation of soluble and aggregated mutant huntingtin in huntington's disease. Chemistry & Biology. 19: 264-75. PMID 22365609 DOI: 10.1016/j.chembiol.2011.12.020  0.304
2012 Kraft AD, Kaltenbach LS, Lo DC, Harry GJ. Activated microglia proliferate at neurites of mutant huntingtin-expressing neurons. Neurobiology of Aging. 33: 621.e17-33. PMID 21482444 DOI: 10.1016/J.Neurobiolaging.2011.02.015  0.422
2011 Christianson MG, Lo DC. Development of a low-pressure microtargeting biolistic device for transfection of retinal explants. Molecular Vision. 17: 2947-55. PMID 22128241  0.737
2011 Gabriel T, García-Pérez E, Mahfooz K, Goñi J, Martínez-Turrillas R, Pérez-Otaño I, Lo DC, Wesseling JF. A new kinetic framework for synaptic vesicle trafficking tested in synapsin knock-outs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11563-77. PMID 21832187 DOI: 10.1523/Jneurosci.1447-11.2011  0.76
2011 Reinhart PH, Kaltenbach LS, Essrich C, Dunn DE, Eudailey JA, DeMarco CT, Turmel GJ, Whaley JC, Wood A, Cho S, Lo DC. Identification of anti-inflammatory targets for Huntington's disease using a brain slice-based screening assay. Neurobiology of Disease. 43: 248-56. PMID 21458569 DOI: 10.1016/j.nbd.2011.03.017  0.334
2010 Kaltenbach LS, Bolton MM, Shah B, Kanju PM, Lewis GM, Turmel GJ, Whaley JC, Trask OJ, Lo DC. Composite primary neuronal high-content screening assay for Huntington's disease incorporating non-cell-autonomous interactions. Journal of Biomolecular Screening. 15: 806-19. PMID 20581077 DOI: 10.1177/1087057110373392  0.703
2010 Crittenden JR, Dunn DE, Merali FI, Woodman B, Yim M, Borkowska AE, Frosch MP, Bates GP, Housman DE, Lo DC, Graybiel AM. CalDAG-GEFI down-regulation in the striatum as a neuroprotective change in Huntington's disease. Human Molecular Genetics. 19: 1756-65. PMID 20147317 DOI: 10.1093/Hmg/Ddq055  0.36
2009 Thompson LM, Aiken CT, Kaltenbach LS, Agrawal N, Illes K, Khoshnan A, Martinez-Vincente M, Arrasate M, O'Rourke JG, Khashwji H, Lukacsovich T, Zhu YZ, Lau AL, Massey A, Hayden MR, ... ... Lo DC, et al. IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. The Journal of Cell Biology. 187: 1083-99. PMID 20026656 DOI: 10.1083/Jcb.200909067  0.313
2009 Roberts AC, Díez-García J, Rodriguiz RM, López IP, Luján R, Martínez-Turrillas R, Picó E, Henson MA, Bernardo DR, Jarrett TM, Clendeninn DJ, López-Mascaraque L, Feng G, Lo DC, Wesseling JF, et al. Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation. Neuron. 63: 342-56. PMID 19679074 DOI: 10.1016/J.Neuron.2009.06.016  0.752
2008 Garcia-Perez E, Lo DC, Wesseling JF. Kinetic isolation of a slowly recovering component of short-term depression during exhaustive use at excitatory hippocampal synapses. Journal of Neurophysiology. 100: 781-95. PMID 18579659 DOI: 10.1152/Jn.90429.2008  0.734
2007 Varma H, Voisine C, DeMarco CT, Cattaneo E, Lo DC, Hart AC, Stockwell BR. Selective inhibitors of death in mutant huntingtin cells. Nature Chemical Biology. 3: 99-100. PMID 17195849 DOI: 10.1038/Nchembio852  0.301
2006 Pérez-Otaño I, Luján R, Tavalin SJ, Plomann M, Modregger J, Liu XB, Jones EG, Heinemann SF, Lo DC, Ehlers MD. Endocytosis and synaptic removal of NR3A-containing NMDA receptors by PACSIN1/syndapin1. Nature Neuroscience. 9: 611-21. PMID 16617342 DOI: 10.1038/nn1680  0.422
2002 Danzer SC, Crooks KR, Lo DC, McNamara JO. Increased expression of brain-derived neurotrophic factor induces formation of basal dendrites and axonal branching in dentate granule cells in hippocampal explant cultures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9754-63. PMID 12427830 DOI: 10.1523/Jneurosci.22-22-09754.2002  0.412
2002 Wesseling JF, Lo DC. Limit on the role of activity in controlling the release-ready supply of synaptic vesicles. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9708-20. PMID 12427826 DOI: 10.1523/Jneurosci.22-22-09708.2002  0.744
2000 Bolton MM, Lo DC, Sherwood NT. Long-term regulation of excitatory and inhibitory synaptic transmission in hippocampal cultures by brain-derived neurotrophic factor. Progress in Brain Research. 128: 203-18. PMID 11105680 DOI: 10.1016/S0079-6123(00)28018-7  0.771
2000 Lesser SS, Lo DC. CNTF II, I presume? Nature Neuroscience. 3: 851-2. PMID 10966608 DOI: 10.1038/78738  0.65
2000 Bolton MM, Pittman AJ, Lo DC. Brain-derived neurotrophic factor differentially regulates excitatory and inhibitory synaptic transmission in hippocampal cultures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3221-32. PMID 10777787 DOI: 10.1523/Jneurosci.20-09-03221.2000  0.731
2000 Yacoubian TA, Lo DC. Truncated and full-length TrkB receptors regulate distinct modes of dendritic growth. Nature Neuroscience. 3: 342-9. PMID 10725923 DOI: 10.1038/73911  0.716
1999 Lesser SS, Holmes TM, Pittman AJ, Lo DC. Induction of electrical excitability by NGF requires autocrine action of a CNTF-like factor. Molecular and Cellular Neurosciences. 14: 169-79. PMID 10576888 DOI: 10.1006/mcne.1999.0778  0.696
1999 Sherwood NT, Lo DC. Long-term enhancement of central synaptic transmission by chronic brain-derived neurotrophic factor treatment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 7025-36. PMID 10436057 DOI: 10.1523/Jneurosci.19-16-07025.1999  0.801
1999 Kryl D, Yacoubian T, Haapasalo A, Castren E, Lo D, Barker PA. Subcellular localization of full-length and truncated Trk receptor isoforms in polarized neurons and epithelial cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 5823-33. PMID 10407023 DOI: 10.1523/Jneurosci.19-14-05823.1999  0.731
1999 McAllister AK, Katz LC, Lo DC. Neurotrophins and synaptic plasticity. Annual Review of Neuroscience. 22: 295-318. PMID 10202541 DOI: 10.1146/annurev.neuro.22.1.295  0.807
1999 McAllister AK, Lo DC, Katz LC. The role of neurotrophins and activity in regulating cortical dendritic growth Developmental Neuropsychology. 16: 335-337. DOI: 10.1207/S15326942Dn1603_9  0.776
1998 Lo DC. Instructive roles of neurotrophins in synaptic plasticity. Progress in Brain Research. 117: 65-70. PMID 9932401 DOI: 10.1016/S0079-6123(08)64008-X  0.455
1997 Lesser SS, Sherwood NT, Lo DC. Neurotrophins differentially regulate voltage-gated ion channels. Molecular and Cellular Neurosciences. 10: 173-83. PMID 9532579 DOI: 10.1006/mcne.1997.0656  0.779
1997 Riddle DR, Katz LC, Lo DC. Focal delivery of neurotrophins into the central nervous system using fluorescent latex microspheres. Biotechniques. 23: 928-34, 936-7. PMID 9383561 DOI: 10.2144/97235Rr02  0.741
1997 McAllister AK, Katz LC, Lo DC. Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth. Neuron. 18: 767-78. PMID 9182801 DOI: 10.1016/S0896-6273(00)80316-5  0.797
1997 Sherwood NT, Lesser SS, Lo DC. Neurotrophin regulation of ionic currents and cell size depends on cell context. Proceedings of the National Academy of Sciences of the United States of America. 94: 5917-22. PMID 9159175 DOI: 10.1073/pnas.94.11.5917  0.778
1996 Riddle DR, McAllister AK, Lo DC, Katz LC. Neurotrophins in cortical development. Cold Spring Harbor Symposia On Quantitative Biology. 61: 85-93. PMID 9246438 DOI: 10.1101/Sqb.1996.061.01.012  0.753
1996 McAllister AK, Katz LC, Lo DC. Neurotrophin regulation of cortical dendritic growth requires activity. Neuron. 17: 1057-64. PMID 8982155 DOI: 10.1016/S0896-6273(00)80239-1  0.808
1995 Lo DC. Neurotrophic factors and synaptic plasticity. Neuron. 15: 979-81. PMID 7576664 DOI: 10.1016/0896-6273(95)90085-3  0.356
1995 McAllister AK, Lo DC, Katz LC. Neurotrophins regulate dendritic growth in developing visual cortex. Neuron. 15: 791-803. PMID 7576629 DOI: 10.1016/0896-6273(95)90171-X  0.804
1995 Lesser SS, Lo DC. Regulation of voltage-gated ion channels by NGF and ciliary neurotrophic factor in SK-N-SH neuroblastoma cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 253-61. PMID 7529828 DOI: 10.1523/Jneurosci.15-01-00253.1995  0.707
1995 Riddle DR, Lo DC, Katz LC. NT-4-mediated rescue of lateral geniculate neurons from effects of monocular deprivation. Nature. 378: 189-91. PMID 7477322 DOI: 10.1038/378189a0  0.755
1994 Pecorino LT, Lo DC, Brockes JP. Isoform-specific induction of a retinoid-responsive antigen after biolistic transfection of chimaeric retinoic acid/thyroid hormone receptors into a regenerating limb. Development (Cambridge, England). 120: 325-33. PMID 8149912  0.518
1994 Lo DC, McAllister AK, Katz LC. Neuronal transfection in brain slices using particle-mediated gene transfer. Neuron. 13: 1263-8. PMID 7993619 DOI: 10.1016/0896-6273(94)90412-X  0.783
1994 Brockes JP, Lo DC. Reversibility of the mononucleate-to-multinucleate myogenic transition during amphibian limb regeneration. Eye (London, England). 8: 151-4. PMID 7958014 DOI: 10.1038/Eye.1994.38  0.561
1993 Lo DC, Allen F, Brockes JP. Reversal of muscle differentiation during urodele limb regeneration. Proceedings of the National Academy of Sciences of the United States of America. 90: 7230-4. PMID 8346239 DOI: 10.1073/Pnas.90.15.7230  0.57
1992 Lo DC. Signal transduction and regulation of neurotrophins. Current Opinion in Neurobiology. 2: 336-40. PMID 1353699 DOI: 10.1016/0959-4388(92)90125-5  0.398
1991 Lo DC, Pinkham JL, Stevens CF. Role of a key cysteine residue in the gating of the acetylcholine receptor. Neuron. 6: 31-40. PMID 1986773 DOI: 10.1016/0896-6273(91)90119-K  0.623
1990 Lo DC, Pinkham JL, Stevens CF. Influence of the gamma subunit and expression system on acetylcholine receptor gating. Neuron. 5: 857-66. PMID 1702647 DOI: 10.1016/0896-6273(90)90345-G  0.625
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