Spencer Szczesny - Publications

Affiliations: 
Orthopaedic Surgery University of Pennsylvania, Philadelphia, PA, United States 

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Pedaprolu K, Szczesny SE. Mouse Achilles tendons exhibit collagen disorganization but minimal collagen denaturation during cyclic loading to failure. Journal of Biomechanics. 151: 111545. PMID 36944295 DOI: 10.1016/j.jbiomech.2023.111545  0.384
2023 Szczesny SE, Corr DT. Tendon cell and tissue culture: Perspectives and recommendations. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 36794495 DOI: 10.1002/jor.25532  0.309
2021 Peterson BE, Rolfe RA, Kunselman A, Murphy P, Szczesny SE. Mechanical Stimulation Muscle Activity Is Necessary for the Maturation of Tendon Multiscale Mechanics During Embryonic Development. Frontiers in Cell and Developmental Biology. 9: 725563. PMID 34540841 DOI: 10.3389/fcell.2021.725563  0.39
2020 Peterson BE, Szczesny SE. Dependence of Tendon Multiscale Mechanics on Sample Gauge Length is Consistent with Discontinuous Collagen Fibrils. Acta Biomaterialia. PMID 33010516 DOI: 10.1016/j.actbio.2020.09.046  0.341
2018 Szczesny SE, Aeppli C, David A, Mauck RL. Fatigue loading of tendon results in collagen kinking and denaturation but does not change local tissue mechanics. Journal of Biomechanics. PMID 29519673 DOI: 10.1016/J.Jbiomech.2018.02.014  0.549
2018 Gong Z, Szczesny SE, Caliari SR, Charrier EE, Chaudhuri O, Cao X, Lin Y, Mauck RL, Janmey PA, Burdick JA, Shenoy VB. Matching material and cellular timescales maximizes cell spreading on viscoelastic substrates. Proceedings of the National Academy of Sciences of the United States of America. PMID 29507238 DOI: 10.1073/Pnas.1716620115  0.519
2017 Szczesny SE, Driscoll TP, Tseng HY, Liu PC, Heo SJ, Mauck RL, Chao PG. Crimped Nanofibrous Biomaterials Mimic Microstructure and Mechanics of Native Tissue and Alter Strain Transfer to Cells. Acs Biomaterials Science & Engineering. 3: 2869-2876. PMID 29147681 DOI: 10.1021/Acsbiomaterials.6B00646  0.66
2017 Heo SJ, Szczesny SE, Kim DH, Saleh KS, Mauck RL. Expansion of Mesenchymal Stem Cells on Electrospun Scaffolds Maintains Stemness, Mechano-Responsivity, and Differentiation Potential. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 29027711 DOI: 10.1002/Jor.23772  0.677
2017 Bansal S, Mandalapu S, Aeppli C, Qu F, Szczesny SE, Mauck RL, Zgonis MH. Mechanical function near defects in an aligned nanofiber composite is preserved by inclusion of disorganized layers: Insight into meniscus structure and function. Acta Biomaterialia. PMID 28159718 DOI: 10.1016/J.Actbio.2017.01.074  0.676
2017 Loebel C, Szczesny SE, Cosgrove BD, Alini M, Zenobi-Wong M, Mauck RL, Eglin D. Crosslinking Chemistry of Tyramine-Modified Hyaluronan Hydrogels Alters Mesenchymal Stem Cell Early Attachment and Behavior. Biomacromolecules. PMID 28146630 DOI: 10.1021/Acs.Biomac.6B01740  0.673
2017 Szczesny SE, Fetchko KL, Dodge GR, Elliott DM. Evidence that interfibrillar load transfer in tendon is supported by small diameter fibrils and not extrafibrillar tissue components. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 28071819 DOI: 10.1002/Jor.23517  0.363
2016 Szczesny SE, Mauck RL. Going Nuclear: Evidence Implicating the Cell Nucleus in Mechanotransduction. Journal of Biomechanical Engineering. PMID 27918797 DOI: 10.1115/1.4035350  0.523
2016 Heo SJ, Han WM, Szczesny SE, Cosgrove BD, Elliott DM, Lee DA, Duncan RL, Mauck RL. Mechanically Induced Chromatin Condensation Requires Cellular Contractility in Mesenchymal Stem Cells. Biophysical Journal. 111: 864-74. PMID 27558729 DOI: 10.1016/J.Bpj.2016.07.006  0.641
2014 Szczesny SE, Edelstein RS, Elliott DM. DTAF dye concentrations commonly used to measure microscale deformations in biological tissues alter tissue mechanics. Plos One. 9: e99588. PMID 24915570 DOI: 10.1371/Journal.Pone.0099588  0.307
2014 Szczesny SE, Elliott DM. Interfibrillar shear stress is the loading mechanism of collagen fibrils in tendon. Acta Biomaterialia. 10: 2582-90. PMID 24530560 DOI: 10.1016/J.Actbio.2014.01.032  0.342
2013 Driscoll TP, Nakasone RH, Szczesny SE, Elliott DM, Mauck RL. Biaxial mechanics and inter-lamellar shearing of stem-cell seeded electrospun angle-ply laminates for annulus fibrosus tissue engineering. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 31: 864-70. PMID 23335319 DOI: 10.1002/Jor.22312  0.669
2012 Szczesny SE, Peloquin JM, Cortes DH, Kadlowec JA, Soslowsky LJ, Elliott DM. Biaxial tensile testing and constitutive modeling of human supraspinatus tendon. Journal of Biomechanical Engineering. 134: 021004. PMID 22482671 DOI: 10.1115/1.4005852  0.385
2011 Lee CS, Szczesny SE, Soslowsky LJ. Remodeling and repair of orthopedic tissue: role of mechanical loading and biologics: part II: cartilage and bone. American Journal of Orthopedics (Belle Mead, N.J.). 40: 122-8. PMID 21720600  0.33
2010 Szczesny SE, Lee CS, Soslowsky LJ. Remodeling and repair of orthopedic tissue: role of mechanical loading and biologics. American Journal of Orthopedics (Belle Mead, N.J.). 39: 525-30. PMID 21623418  0.327
2010 Smith LJ, Martin JT, Szczesny SE, Ponder KP, Haskins ME, Elliott DM. Altered lumbar spine structure, biochemistry, and biomechanical properties in a canine model of mucopolysaccharidosis type VII. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 28: 616-22. PMID 19918911 DOI: 10.1002/Jor.21030  0.411
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