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Gilbert Chu - Publications

Affiliations: 
Biochemistry Stanford University School of Medicine, Palo Alto, CA, United States 
Area:
DNA repair
Website:
http://cmgm.stanford.edu/~chu/members1.html
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52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Tsai CJ, Chu G. Cooperative assembly of a protein-DNA filament for nonhomologous end joining. The Journal of Biological Chemistry. 288: 18110-20. PMID 23620595 DOI: 10.1074/Jbc.M113.464115  0.5
2012 Tsai C, Smider V, Hwang BJ, Chu G. Electrophoretic mobility shift assays for protein-DNA complexes involved in DNA repair. Methods in Molecular Biology (Clifton, N.J.). 920: 53-78. PMID 22941596 DOI: 10.1007/978-1-61779-998-3_5  0.51
2009 Hong WJ, Tibshirani R, Chu G. Local false discovery rate facilitates comparison of different microarray experiments. Nucleic Acids Research. 37: 7483-97. PMID 19825981 DOI: 10.1093/Nar/Gkp813  0.312
2008 Chu G, Yang W. Here comes the sun: recognition of UV-damaged DNA. Cell. 135: 1172-4. PMID 19109889 DOI: 10.1016/J.Cell.2008.12.015  0.484
2007 Andres SN, Modesti M, Tsai CJ, Chu G, Junop MS. Crystal structure of human XLF: a twist in nonhomologous DNA end-joining. Molecular Cell. 28: 1093-101. PMID 18158905 DOI: 10.1016/J.Molcel.2007.10.024  0.458
2007 Tsai CJ, Kim SA, Chu G. Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends. Proceedings of the National Academy of Sciences of the United States of America. 104: 7851-6. PMID 17470781 DOI: 10.1073/Pnas.0702620104  0.522
2007 Budman J, Kim SA, Chu G. Processing of DNA for nonhomologous end-joining is controlled by kinase activity and XRCC4/ligase IV. The Journal of Biological Chemistry. 282: 11950-9. PMID 17272270 DOI: 10.1074/Jbc.M610058200  0.459
2006 Budman J, Chu G. Assays for nonhomologous end joining in extracts. Methods in Enzymology. 408: 430-44. PMID 16793385 DOI: 10.1016/S0076-6879(06)08027-X  0.476
2006 Smider V, Hwang BJ, Chu G. Electrophoretic mobility shift assays to study protein binding to damaged DNA. Methods in Molecular Biology (Clifton, N.J.). 314: 323-44. PMID 16673891 DOI: 10.1385/1-59259-973-7:323  0.498
2005 Sugasawa K, Okuda Y, Saijo M, Nishi R, Matsuda N, Chu G, Mori T, Iwai S, Tanaka K, Tanaka K, Hanaoka F. UV-induced ubiquitylation of XPC protein mediated by UV-DDB-ubiquitin ligase complex. Cell. 121: 387-400. PMID 15882621 DOI: 10.1016/J.Cell.2005.02.035  0.432
2005 Budman J, Chu G. Processing of DNA for nonhomologous end-joining by cell-free extract. The Embo Journal. 24: 849-60. PMID 15692565 DOI: 10.1038/sj.emboj.7600563  0.416
2004 Rieger KE, Chu G. Portrait of transcriptional responses to ultraviolet and ionizing radiation in human cells. Nucleic Acids Research. 32: 4786-803. PMID 15356296 DOI: 10.1093/Nar/Gkh783  0.399
2003 Tibshirani R, Hastie T, Narasimhan B, Chu G. Class Prediction by Nearest Shrunken Centroids, with Applications to DNA Microarrays Statistical Science. 18: 104-117. DOI: 10.1214/Ss/1056397488  0.369
2002 Tang J, Chu G. Xeroderma pigmentosum complementation group E and UV-damaged DNA-binding protein. Dna Repair. 1: 601-16. PMID 12509284 DOI: 10.1016/S1568-7864(02)00052-6  0.504
2002 Chu G. Global genomic repair and p53 in a dance after DNA damage. Cancer Biology & Therapy. 1: 150-1. PMID 12212613 DOI: 10.4161/Cbt.60  0.379
2002 Cong F, Tang J, Hwang BJ, Vuong BQ, Chu G, Goff SP. Interaction between UV-damaged DNA binding activity proteins and the c-Abl tyrosine kinase. The Journal of Biological Chemistry. 277: 34870-8. PMID 12107171 DOI: 10.1074/Jbc.M204416200  0.551
2002 DeFazio LG, Stansel RM, Griffith JD, Chu G. Synapsis of DNA ends by DNA-dependent protein kinase. The Embo Journal. 21: 3192-200. PMID 12065431 DOI: 10.1093/Emboj/Cdf299  0.509
2002 Tan T, Chu G. p53 Binds and activates the xeroderma pigmentosum DDB2 gene in humans but not mice. Molecular and Cellular Biology. 22: 3247-54. PMID 11971958 DOI: 10.1128/Mcb.22.10.3247-3254.2002  0.397
2001 Thorstenson YR, Shen P, Tusher VG, Wayne TL, Davis RW, Chu G, Oefner PJ. Global analysis of ATM polymorphism reveals significant functional constraint. American Journal of Human Genetics. 69: 396-412. PMID 11443540 DOI: 10.1086/321296  0.309
2001 Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proceedings of the National Academy of Sciences of the United States of America. 98: 5116-21. PMID 11309499 DOI: 10.1073/Pnas.091062498  0.381
2000 Tang JY, Hwang BJ, Ford JM, Hanawalt PC, Chu G. Xeroderma pigmentosum p48 gene enhances global genomic repair and suppresses UV-induced mutagenesis. Molecular Cell. 5: 737-44. PMID 10882109 DOI: 10.1016/S1097-2765(00)80252-X  0.498
2000 Hammarsten O, DeFazio LG, Chu G. Activation of DNA-dependent protein kinase by single-stranded DNA ends. The Journal of Biological Chemistry. 275: 1541-50. PMID 10636842 DOI: 10.1074/Jbc.275.3.1541  0.507
1999 Hwang BJ, Smider V, Chu G. The use of electrophoretic mobility shift assays to study DNA repair Methods in Molecular Biology (Clifton, N.J.). 113: 103-120. PMID 10443414 DOI: 10.1385/1-59259-675-4:103  0.461
1999 Leuther KK, Hammarsten O, Kornberg RD, Chu G. Structure of DNA-dependent protein kinase: implications for its regulation by DNA. The Embo Journal. 18: 1114-23. PMID 10064579 DOI: 10.1093/Emboj/18.5.1114  0.506
1999 Hwang BJ, Ford JM, Hanawalt PC, Chu G. Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair. Proceedings of the National Academy of Sciences of the United States of America. 96: 424-8. PMID 9892649 DOI: 10.1073/Pnas.96.2.424  0.423
1998 Smider V, Rathmell WK, Brown G, Lewis S, Chu G. Failure of hairpin-ended and nicked DNA To activate DNA-dependent protein kinase: implications for V(D)J recombination. Molecular and Cellular Biology. 18: 6853-8. PMID 9774698 DOI: 10.1128/Mcb.18.11.6853  0.655
1998 Hwang BJ, Toering S, Francke U, Chu G. p48 Activates a UV-damaged-DNA binding factor and is defective in xeroderma pigmentosum group E cells that lack binding activity. Molecular and Cellular Biology. 18: 4391-9. PMID 9632823 DOI: 10.1128/Mcb.18.7.4391  0.407
1998 Hammarsten O, Chu G. DNA-dependent protein kinase: DNA binding and activation in the absence of Ku. Proceedings of the National Academy of Sciences of the United States of America. 95: 525-30. PMID 9435225 DOI: 10.1073/Pnas.95.2.525  0.502
1997 Chu G. Double strand break repair. The Journal of Biological Chemistry. 272: 24097-100. PMID 9305850 DOI: 10.1074/Jbc.272.39.24097  0.495
1997 Smider V, Chu G. The end-joining reaction in V(D)J recombination. Seminars in Immunology. 9: 189-97. PMID 9200330 DOI: 10.1006/Smim.1997.0070  0.5
1997 Rathmell WK, Kaufmann WK, Hurt JC, Byrd LL, Chu G. DNA-dependent protein kinase is not required for accumulation of p53 or cell cycle arrest after DNA damage. Cancer Research. 57: 68-74. PMID 8988043  0.639
1996 Chu G. Role of the Ku autoantigen in V(D)J recombination and double-strand break repair Current Topics in Microbiology and Immunology. 217: 113-132. PMID 8787621 DOI: 10.1007/978-3-642-50140-1_8  0.464
1996 Errami A, Smider V, Rathmell WK, He DM, Hendrickson EA, Zdzienicka MZ, Chu G. Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants. Molecular and Cellular Biology. 16: 1519-26. PMID 8657125 DOI: 10.1128/Mcb.16.4.1519  0.617
1996 Hwang BJ, Liao JC, Chu G. Isolation of a cDNA encoding a UV-damaged DNA binding factor defective in xeroderma pigmentosum group E cells Mutation Research - Dna Repair. 362: 105-117. PMID 8538642 DOI: 10.1016/0921-8777(95)00040-2  0.439
1994 Rathmell WK, Chu G. Involvement of the Ku autoantigen in the cellular response to DNA double-strand breaks. Proceedings of the National Academy of Sciences of the United States of America. 91: 7623-7. PMID 8052631 DOI: 10.1073/Pnas.91.16.7623  0.678
1994 Fox ME, Feldman BJ, Chu G. A novel role for DNA photolyase: binding to DNA damaged by drugs is associated with enhanced cytotoxicity in Saccharomyces cerevisiae. Molecular and Cellular Biology. 14: 8071-7. PMID 7969145 DOI: 10.1128/Mcb.14.12.8071  0.473
1994 Smider V, Rathmell WK, Lieber MR, Chu G. Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA. Science (New York, N.Y.). 266: 288-91. PMID 7939667 DOI: 10.1126/Science.7939667  0.665
1994 Payne A, Chu G. Xeroderma pigmentosum group E binding factor recognizes a broad spectrum of DNA damage. Mutation Research. 310: 89-102. PMID 7523888 DOI: 10.1016/0027-5107(94)90012-4  0.48
1994 Rathmell WK, Chu G. A DNA end-binding factor involved in double-strand break repair and V(D)J recombination. Molecular and Cellular Biology. 14: 4741-8. PMID 7516471 DOI: 10.1128/Mcb.14.7.4741  0.661
1992 Chu G. Bag model for DNA migration during pulsed-field electrophoresis. Proceedings of the National Academy of Sciences of the United States of America. 88: 11071-5. PMID 1763022 DOI: 10.1073/Pnas.88.24.11071  0.361
1991 Gunderson K, Chu G. Pulsed-Field Electrophoresis of Megabase-Sized DNA Molecular and Cellular Biology. 11: 3348-3354. PMID 2038337 DOI: 10.1128/Mcb.11.6.3348  0.403
1991 Chu G, Gunderson K. Separation of large DNA by a variable-angle contour-clamped homogeneous electric field apparatus Analytical Biochemistry. 194: 439-446. PMID 1862945 DOI: 10.1016/0003-2697(91)90254-Q  0.364
1990 Chu G, Chang E. Cisplatin-resistant cells express increased levels of a factor that recognizes damaged DNA. Proceedings of the National Academy of Sciences of the United States of America. 87: 3324-7. PMID 2333286 DOI: 10.1073/Pnas.87.9.3324  0.459
1989 Patterson M, Chu G. Evidence that xeroderma pigmentosum cells from complementation group E are deficient in a homolog of yeast photolyase. Molecular and Cellular Biology. 9: 5105-5112. PMID 2689872 DOI: 10.1128/Mcb.9.11.5105  0.458
1989 Chu G. Pulsed field electrophoresis in contour-clamped homogeneous electric fields for the resolution of DNA by size or topology. Electrophoresis. 10: 290-5. PMID 2670544 DOI: 10.1002/Elps.1150100504  0.374
1988 Chu G, Chang E. Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNA. Science (New York, N.Y.). 242: 564-7. PMID 3175673 DOI: 10.1126/Science.3175673  0.511
1987 Chu G, Berg P. DNA cross-linked by cisplatin: a new probe for the DNA repair defect in xeroderma pigmentosum. Molecular Biology & Medicine. 4: 277-90. PMID 3695939  0.574
1987 Chu G, Vollrath D, Davis RW. Separation of large DNA molecules by contour-clamped homogeneous electric fields. Science (New York, N.Y.). 234: 1582-5. PMID 3538420 DOI: 10.1126/Science.3538420  0.383
1987 Chu G, Hayakawa H, Berg P. Electroporation for the efficient transfection of mammalian cells with DNA. Nucleic Acids Research. 15: 1311-26. PMID 3029703 DOI: 10.1093/Nar/15.3.1311  0.576
1985 Chu G, Berg P. Rapid assay for detection of Escherichia coli xanthine-guanine phosphoribosyltransferase activity in transduced cells. Nucleic Acids Research. 13: 2921-30. PMID 3889850 DOI: 10.1093/Nar/13.8.2921  0.477
1985 Naumovski L, Chu G, Berg P, Friedberg EC. RAD3 gene of Saccharomyces cerevisiae: nucleotide sequence of wild-type and mutant alleles, transcript mapping, and aspects of gene regulation. Molecular and Cellular Biology. 5: 17-26. PMID 3885009 DOI: 10.1128/Mcb.5.1.17  0.541
1981 Chu G, Sharp PA. SV40 DNA transfection of cells in suspension: analysis of efficiency of transcription and translation of T-antigen. Gene. 13: 197-202. PMID 6263759 DOI: 10.1016/0378-1119(81)90008-1  0.434
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