| Year |
Citation |
Score |
| 2021 |
Leger A, Amaral PP, Pandolfini L, Capitanchik C, Capraro F, Miano V, Migliori V, Toolan-Kerr P, Sideri T, Enright AJ, Tzelepis K, van Werven FJ, Luscombe NM, Barbieri I, Ule J, ... ... Kouzarides T, et al. RNA modifications detection by comparative Nanopore direct RNA sequencing. Nature Communications. 12: 7198. PMID 34893601 DOI: 10.1038/s41467-021-27393-3 |
0.717 |
|
| 2021 |
Santos-Rosa H, Millán-Zambrano G, Han N, Leonardi T, Klimontova M, Nasiscionyte S, Pandolfini L, Tzelepis K, Bartke T, Kouzarides T. Methylation of histone H3 at lysine 37 by Set1 and Set2 prevents spurious DNA replication. Molecular Cell. PMID 33979575 DOI: 10.1016/j.molcel.2021.04.021 |
0.747 |
|
| 2020 |
Kouzarides T, Pandolfini L, Barbieri I, Bannister AJ, Andrews B. Further Evidence Supporting N7-Methylation of Guanosine (mG) in Human MicroRNAs. Molecular Cell. 79: 201-202. PMID 32679073 DOI: 10.1016/J.Molcel.2020.05.023 |
0.719 |
|
| 2020 |
Barbieri I, Kouzarides T. Role of RNA modifications in cancer. Nature Reviews. Cancer. PMID 32300195 DOI: 10.1038/S41568-020-0253-2 |
0.366 |
|
| 2020 |
Wein S, Andrews B, Sachsenberg T, Santos-Rosa H, Kohlbacher O, Kouzarides T, Garcia BA, Weisser H. A computational platform for high-throughput analysis of RNA sequences and modifications by mass spectrometry. Nature Communications. 11: 926. PMID 32066737 DOI: 10.1038/S41467-020-14665-7 |
0.324 |
|
| 2019 |
Tzelepis K, Rausch O, Kouzarides T. RNA-modifying enzymes and their function in a chromatin context. Nature Structural & Molecular Biology. 26: 858-862. PMID 31582848 DOI: 10.1038/S41594-019-0312-0 |
0.42 |
|
| 2019 |
Samudyata, Amaral PP, Engström PG, Robson SC, Nielsen ML, Kouzarides T, Castelo-Branco G. Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells. Experimental Cell Research. PMID 31077711 DOI: 10.1016/J.Yexcr.2019.05.006 |
0.729 |
|
| 2019 |
Pandolfini L, Barbieri I, Bannister AJ, Hendrick A, Andrews B, Webster N, Murat P, Mach P, Brandi R, Robson SC, Migliori V, Alendar A, d'Onofrio M, Balasubramanian S, Kouzarides T. METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation. Molecular Cell. PMID 31031083 DOI: 10.1016/J.Molcel.2019.03.040 |
0.718 |
|
| 2019 |
Wiese M, Bannister AJ, Basu S, Boucher W, Wohlfahrt K, Christophorou MA, Nielsen ML, Klenerman D, Laue ED, Kouzarides T. Citrullination of HP1γ chromodomain affects association with chromatin. Epigenetics & Chromatin. 12: 21. PMID 30940194 DOI: 10.1186/S13072-019-0265-X |
0.447 |
|
| 2019 |
Albertella M, Blackaby W, Fosbeary R, Hendrick A, Leggate D, Ofir-Rosenfeld Y, Sapetschnig A, Tzelepis K, Yankova E, Kouzarides T, Rausch O. Abstract B126: A small molecule inhibitor of the RNA m6A writer METTL3 inhibits the development of acute myeloid leukemia (AML) in vivo Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-B126 |
0.326 |
|
| 2018 |
Tzelepis K, De Braekeleer E, Aspris D, Barbieri I, Vijayabaskar MS, Liu WH, Gozdecka M, Metzakopian E, Toop HD, Dudek M, Robson SC, Hermida-Prado F, Yang YH, Babaei-Jadidi R, Garyfallos DA, ... ... Kouzarides T, et al. SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4. Nature Communications. 9: 5378. PMID 30568163 DOI: 10.1038/S41467-018-07620-0 |
0.385 |
|
| 2018 |
Millan-Zambrano G, Santos-Rosa H, Puddu F, Robson SC, Jackson SP, Kouzarides T. Phosphorylation of Histone H4T80 Triggers DNA Damage Checkpoint Recovery. Molecular Cell. 72: 625-635.e4. PMID 30454561 DOI: 10.1016/J.Molcel.2018.09.023 |
0.357 |
|
| 2018 |
Larrieu D, Viré E, Robson S, Breusegem SY, Kouzarides T, Jackson SP. Inhibition of the acetyltransferase NAT10 normalizes progeric and aging cells by rebalancing the Transportin-1 nuclear import pathway. Science Signaling. 11. PMID 29970603 DOI: 10.1126/Scisignal.Aar5401 |
0.343 |
|
| 2018 |
Santos-Rosa H, Schneider R, Bernstein BE, Karabetsou N, Morillon A, Weise C, Schreiber SL, Mellor J, Kouzarides T. Methylation of Histone H3 K4 Mediates Association of the Isw1p ATPase with Chromatin. Molecular Cell. 70: 983. PMID 29883612 DOI: 10.1016/j.molcel.2018.05.012 |
0.317 |
|
| 2018 |
Cannizzaro E, Bannister AJ, Han N, Alendar A, Kouzarides T. DDX3X RNA helicase affects breast cancer cell cycle progression by regulating expression of KLF4. Febs Letters. PMID 29782654 DOI: 10.1002/1873-3468.13106 |
0.363 |
|
| 2018 |
Amaral PP, Leonardi T, Han N, Viré E, Gascoigne DK, Arias-Carrasco R, Büscher M, Pandolfini L, Zhang A, Pluchino S, Maracaja-Coutinho V, Nakaya HI, Hemberg M, Shiekhattar R, Enright AJ, ... Kouzarides T, et al. Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci. Genome Biology. 19: 32. PMID 29540241 DOI: 10.1186/S13059-018-1405-5 |
0.731 |
|
| 2017 |
Barbieri I, Tzelepis K, Pandolfini L, Shi J, Millán-Zambrano G, Robson SC, Aspris D, Migliori V, Bannister AJ, Han N, De Braekeleer E, Ponstingl H, Hendrick A, Vakoc CR, Vassiliou GS, ... Kouzarides T, et al. Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control. Nature. 552: 126-131. PMID 29186125 DOI: 10.1038/Nature24678 |
0.787 |
|
| 2017 |
Li MA, Amaral PP, Cheung P, Bergmann JH, Kinoshita M, Kalkan T, Ralser M, Robson S, Meyenn FV, Paramor M, Yang F, Chen C, Nichols J, Spector DL, Kouzarides T, et al. A lncRNA fine tunes the dynamics of a cell state transition involving Lin28, let-7 and de novo DNA methylation. Elife. 6. PMID 28820723 DOI: 10.7554/Elife.23468 |
0.413 |
|
| 2017 |
Sayou C, Millán-Zambrano G, Santos-Rosa H, Petfalski E, Robson S, Houseley J, Kouzarides T, Tollervey D. RNA binding by the histone methyltransferases Set1 and Set2. Molecular and Cellular Biology. PMID 28483910 DOI: 10.1128/Mcb.00165-17 |
0.439 |
|
| 2017 |
Li MA, Amaral PP, Cheung P, Bergmann JH, Kinoshita M, Kalkan T, Ralser M, Robson S, Meyenn Fv, Paramor M, Yang F, Chen C, Nichols J, Spector DL, Kouzarides T, et al. Author response: A lncRNA fine tunes the dynamics of a cell state transition involving Lin28, let-7 and de novo DNA methylation Elife. DOI: 10.7554/Elife.23468.032 |
0.332 |
|
| 2016 |
Gilan O, Lam EY, Becher I, Lugo D, Cannizzaro E, Joberty G, Ward A, Wiese M, Fong CY, Ftouni S, Tyler D, Stanley K, MacPherson L, Weng CF, Chan YC, ... ... Kouzarides T, et al. Functional interdependence of BRD4 and DOT1L in MLL leukemia. Nature Structural & Molecular Biology. PMID 27294782 DOI: 10.1038/Nsmb.3249 |
0.504 |
|
| 2015 |
Picaud S, Fedorov O, Thanasopoulou A, Leonards K, Jones K, Meier J, Olzscha H, Monteiro O, Martin S, Philpott M, Tumber A, Filippakopoulos P, Yapp C, Wells C, Hing Che K, ... ... Kouzarides T, et al. Generation of a selective small molecule inhibitor of the CBP/p300 bromodomain for leukemia therapy. Cancer Research. PMID 26552700 DOI: 10.1158/0008-5472.Can-15-0236 |
0.36 |
|
| 2015 |
McConnell MJ, Durand L, Langley E, Coste-Sarguet L, Zelent A, Chomienne C, Kouzarides T, Licht JD, Guidez F. Post transcriptional control of the epigenetic stem cell regulator PLZF by sirtuin and HDAC deacetylases. Epigenetics & Chromatin. 8: 38. PMID 26405459 DOI: 10.1186/S13072-015-0030-8 |
0.516 |
|
| 2015 |
Fong CY, Gilan O, Lam EY, Rubin AF, Ftouni S, Tyler D, Stanley K, Sinha D, Yeh P, Morison J, Giotopoulos G, Lugo D, Jeffrey P, Lee SC, Carpenter C, ... ... Kouzarides T, et al. BET inhibitor resistance emerges from leukaemia stem cells. Nature. 525: 538-42. PMID 26367796 DOI: 10.1038/Nature14888 |
0.339 |
|
| 2015 |
Theodoulou NH, Bamborough P, Bannister AJ, Becher I, Bit RA, Che KH, Chung CW, Dittmann A, Drewes G, Drewry DH, Gordon L, Grandi P, Leveridge M, Lindon M, Michon AM, ... ... Kouzarides T, et al. Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition. Journal of Medicinal Chemistry. PMID 25856009 DOI: 10.1021/Acs.Jmedchem.5B00256 |
0.409 |
|
| 2014 |
Tessarz P, Kouzarides T. Histone core modifications regulating nucleosome structure and dynamics. Nature Reviews. Molecular Cell Biology. 15: 703-8. PMID 25315270 DOI: 10.1038/Nrm3890 |
0.507 |
|
| 2014 |
Xu H, Xian J, Vire E, McKinney S, Wei V, Wong J, Tong R, Kouzarides T, Caldas C, Aparicio S. Up-regulation of the interferon-related genes in BRCA2 knockout epithelial cells. The Journal of Pathology. 234: 386-97. PMID 25043256 DOI: 10.1002/Path.4404 |
0.346 |
|
| 2014 |
Christophorou MA, Castelo-Branco G, Halley-Stott RP, Oliveira CS, Loos R, Radzisheuskaya A, Mowen KA, Bertone P, Silva JC, Zernicka-Goetz M, Nielsen ML, Gurdon JB, Kouzarides T. Citrullination regulates pluripotency and histone H1 binding to chromatin. Nature. 507: 104-8. PMID 24463520 DOI: 10.1038/Nature12942 |
0.751 |
|
| 2014 |
Tessarz P, Santos-Rosa H, Robson SC, Sylvestersen KB, Nelson CJ, Nielsen ML, Kouzarides T. Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification. Nature. 505: 564-8. PMID 24352239 DOI: 10.1038/Nature12819 |
0.518 |
|
| 2014 |
Dawson MA, Gudgin EJ, Horton SJ, Giotopoulos G, Meduri E, Robson S, Cannizzaro E, Osaki H, Wiese M, Putwain S, Fong CY, Grove C, Craig J, Dittmann A, Lugo D, ... ... Kouzarides T, et al. Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia. Leukemia. 28: 311-20. PMID 24220271 DOI: 10.1038/Leu.2013.338 |
0.343 |
|
| 2014 |
Wyspia?ska BS, Bannister AJ, Barbieri I, Nangalia J, Godfrey A, Calero-Nieto FJ, Robson S, Rioja I, Li J, Wiese M, Cannizzaro E, Dawson MA, Huntly B, Prinjha RK, Green AR, ... ... Kouzarides T, et al. BET protein inhibition shows efficacy against JAK2V617F-driven neoplasms. Leukemia. 28: 88-97. PMID 23929215 DOI: 10.1038/Leu.2013.234 |
0.408 |
|
| 2014 |
Ismail HM, Hurd PJ, Khalil MI, Kouzarides T, Bannister A, Gout I. S6 kinase 2 is bound to chromatin-nuclear matrix cellular fractions and is able to phosphorylate histone H3 at threonine 45 in vitro and in vivo. Journal of Cellular Biochemistry. 115: 1048-62. PMID 23564320 DOI: 10.1002/Jcb.24566 |
0.455 |
|
| 2013 |
Castelo-Branco G, Amaral PP, Engström PG, Robson SC, Marques SC, Bertone P, Kouzarides T. The non-coding snRNA 7SK controls transcriptional termination, poising, and bidirectionality in embryonic stem cells. Genome Biology. 14: R98. PMID 24044525 DOI: 10.1186/Gb-2013-14-9-R98 |
0.738 |
|
| 2012 |
Dawson MA, Foster SD, Bannister AJ, Robson SC, Hannah R, Wang X, Xhemalce B, Wood AD, Green AR, Göttgens B, Kouzarides T. Three distinct patterns of histone H3Y41 phosphorylation mark active genes. Cell Reports. 2: 470-7. PMID 22999934 DOI: 10.1016/J.Celrep.2012.08.016 |
0.499 |
|
| 2012 |
Ougland R, Lando D, Jonson I, Dahl JA, Moen MN, Nordstrand LM, Rognes T, Lee JT, Klungland A, Kouzarides T, Larsen E. ALKBH1 is a histone H2A dioxygenase involved in neural differentiation. Stem Cells (Dayton, Ohio). 30: 2672-82. PMID 22961808 DOI: 10.1002/Stem.1228 |
0.468 |
|
| 2012 |
Dawson MA, Kouzarides T, Huntly BJ. Targeting epigenetic readers in cancer. The New England Journal of Medicine. 367: 647-57. PMID 22894577 DOI: 10.1056/Nejmra1112635 |
0.411 |
|
| 2012 |
Dawson MA, Kouzarides T. Cancer epigenetics: from mechanism to therapy. Cell. 150: 12-27. PMID 22770212 DOI: 10.1016/J.Cell.2012.06.013 |
0.45 |
|
| 2012 |
Watson AA, Mahajan P, Mertens HD, Deery MJ, Zhang W, Pham P, Du X, Bartke T, Zhang W, Edlich C, Berridge G, Chen Y, Burgess-Brown NA, Kouzarides T, Wiechens N, et al. The PHD and chromo domains regulate the ATPase activity of the human chromatin remodeler CHD4. Journal of Molecular Biology. 422: 3-17. PMID 22575888 DOI: 10.1016/J.Jmb.2012.04.031 |
0.451 |
|
| 2012 |
Lando D, Balmer J, Laue ED, Kouzarides T. The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia. Plos One. 7: e29765. PMID 22235339 DOI: 10.1371/Journal.Pone.0029765 |
0.492 |
|
| 2011 |
Dawson MA, Prinjha RK, Dittmann A, Giotopoulos G, Bantscheff M, Chan WI, Robson SC, Chung CW, Hopf C, Savitski MM, Huthmacher C, Gudgin E, Lugo D, Beinke S, Chapman TD, ... ... Kouzarides T, et al. Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia. Nature. 478: 529-33. PMID 21964340 DOI: 10.1182/Blood.V118.21.55.55 |
0.45 |
|
| 2011 |
Bannister AJ, Kouzarides T. Regulation of chromatin by histone modifications. Cell Research. 21: 381-95. PMID 21321607 DOI: 10.1038/Cr.2011.22 |
0.487 |
|
| 2011 |
Bartke T, Kouzarides T. Decoding the chromatin modification landscape. Cell Cycle (Georgetown, Tex.). 10: 182. PMID 21224725 DOI: 10.4161/Cc.10.2.14477 |
0.512 |
|
| 2011 |
Griffiths DS, Li J, Dawson MA, Trotter MW, Cheng YH, Smith AM, Mansfield W, Liu P, Kouzarides T, Nichols J, Bannister AJ, Green AR, Göttgens B. LIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease. Nature Cell Biology. 13: 13-21. PMID 21151131 DOI: 10.1038/Ncb2135 |
0.378 |
|
| 2010 |
Bartke T, Vermeulen M, Xhemalce B, Robson SC, Mann M, Kouzarides T. Nucleosome-interacting proteins regulated by DNA and histone methylation. Cell. 143: 470-84. PMID 21029866 DOI: 10.1016/J.Cell.2010.10.012 |
0.494 |
|
| 2010 |
Xhemalce B, Kouzarides T. A chromodomain switch mediated by histone H3 Lys 4 acetylation regulates heterochromatin assembly. Genes & Development. 24: 647-52. PMID 20299449 DOI: 10.1101/Gad.1881710 |
0.493 |
|
| 2010 |
Murata K, Kouzarides T, Bannister AJ, Gurdon JB. Histone H3 lysine 4 methylation is associated with the transcriptional reprogramming efficiency of somatic nuclei by oocytes. Epigenetics & Chromatin. 3: 4. PMID 20181087 DOI: 10.1186/1756-8935-3-4 |
0.475 |
|
| 2009 |
Dawson MA, Bannister AJ, Göttgens B, Foster SD, Bartke T, Green AR, Kouzarides T. JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin. Nature. 461: 819-22. PMID 19783980 DOI: 10.1038/Nature08448 |
0.42 |
|
| 2009 |
Hurd PJ, Bannister AJ, Halls K, Dawson MA, Vermeulen M, Olsen JV, Ismail H, Somers J, Mann M, Owen-Hughes T, Gout I, Kouzarides T. Phosporylation of histone H3 Thr-45 is linked to apoptosis Journal of Biological Chemistry. 284: 16575-16583. PMID 19363025 DOI: 10.1074/Jbc.M109.005421 |
0.441 |
|
| 2009 |
Berger SL, Kouzarides T, Shiekhattar R, Shilatifard A. An operational definition of epigenetics. Genes & Development. 23: 781-3. PMID 19339683 DOI: 10.1101/Gad.1787609 |
0.413 |
|
| 2009 |
Kirmizis A, Santos-Rosa H, Penkett CJ, Singer MA, Green RD, Kouzarides T. Distinct transcriptional outputs associated with mono- and dimethylated histone H3 arginine 2. Nature Structural & Molecular Biology. 16: 449-51. PMID 19270702 DOI: 10.1038/Nsmb.1569 |
0.774 |
|
| 2009 |
Santos-Rosa H, Kirmizis A, Nelson C, Bartke T, Saksouk N, Cote J, Kouzarides T. Histone H3 tail clipping regulates gene expression. Nature Structural & Molecular Biology. 16: 17-22. PMID 19079264 DOI: 10.1038/Nsmb.1534 |
0.755 |
|
| 2008 |
Smith AE, Hurd PJ, Bannister AJ, Kouzarides T, Ford KG. Heritable gene repression through the action of a directed DNA methyltransferase at a chromosomal locus Journal of Biological Chemistry. 283: 9878-9885. PMID 18272522 DOI: 10.1074/Jbc.M710393200 |
0.458 |
|
| 2007 |
Kouzarides T. SnapShot: Histone-modifying enzymes. Cell. 131: 822. PMID 18022374 DOI: 10.1016/J.Cell.2007.11.005 |
0.417 |
|
| 2007 |
Kirmizis A, Santos-Rosa H, Penkett CJ, Singer MA, Vermeulen M, Mann M, Bähler J, Green RD, Kouzarides T. Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylation. Nature. 449: 928-32. PMID 17898715 DOI: 10.1038/Nature06160 |
0.77 |
|
| 2007 |
Opel M, Lando D, Bonilla C, Trewick SC, Boukaba A, Walfridsson J, Cauwood J, Werler PJ, Carr AM, Kouzarides T, Murzina NV, Allshire RC, Ekwall K, Laue ED. Genome-wide studies of histone demethylation catalysed by the fission yeast homologues of mammalian LSD1. Plos One. 2: e386. PMID 17440621 DOI: 10.1371/Journal.Pone.0000386 |
0.533 |
|
| 2007 |
Xhemalce B, Miller KM, Driscoll R, Masumoto H, Jackson SP, Kouzarides T, Verreault A, Arcangioli B. Regulation of histone H3 lysine 56 acetylation in Schizosaccharomyces pombe. The Journal of Biological Chemistry. 282: 15040-7. PMID 17369611 DOI: 10.1074/Jbc.M701197200 |
0.477 |
|
| 2007 |
Kouzarides T. Chromatin modifications and their function. Cell. 128: 693-705. PMID 17320507 DOI: 10.1016/J.Cell.2007.02.005 |
0.469 |
|
| 2007 |
Torres-Padilla ME, Parfitt DE, Kouzarides T, Zernicka-Goetz M. Histone arginine methylation regulates pluripotency in the early mouse embryo. Nature. 445: 214-8. PMID 17215844 DOI: 10.1038/Nature05458 |
0.441 |
|
| 2007 |
Ford KG, Hurd PJ, Bannister AJ, Kouzarides T, Smith AE. Directed De Novo DNA Methylation of a Genomic Locus Leads to Heritable Transcriptional Repression. Blood. 110: 343-343. DOI: 10.1182/blood.v110.11.343.343 |
0.371 |
|
| 2006 |
Burgers WA, Blanchon L, Pradhan S, de Launoit Y, Kouzarides T, Fuks F. Viral oncoproteins target the DNA methyltransferases. Oncogene. 26: 1650-5. PMID 16983344 DOI: 10.1038/Sj.Onc.1209950 |
0.4 |
|
| 2006 |
Nelson CJ, Santos-Rosa H, Kouzarides T. Proline isomerization of histone H3 regulates lysine methylation and gene expression. Cell. 126: 905-16. PMID 16959570 DOI: 10.1016/J.Cell.2006.07.026 |
0.51 |
|
| 2006 |
Ancelin K, Lange UC, Hajkova P, Schneider R, Bannister AJ, Kouzarides T, Surani MA. Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells. Nature Cell Biology. 8: 623-30. PMID 16699504 DOI: 10.1038/Ncb1413 |
0.495 |
|
| 2006 |
OzdaÄŸ H, Teschendorff AE, Ahmed AA, Hyland SJ, Blenkiron C, Bobrow L, Veerakumarasivam A, Burtt G, Subkhankulova T, Arends MJ, Collins VP, Bowtell D, Kouzarides T, Brenton JD, Caldas C. Differential expression of selected histone modifier genes in human solid cancers. Bmc Genomics. 7: 90. PMID 16638127 DOI: 10.1186/1471-2164-7-90 |
0.436 |
|
| 2006 |
Torres-Padilla ME, Bannister AJ, Hurd PJ, Kouzarides T, Zernicka-Goetz M. Dynamic distribution of the replacement histone variant H3.3 in the mouse oocyte and preimplantation embryos International Journal of Developmental Biology. 50: 455-461. PMID 16586346 DOI: 10.1387/Ijdb.052073Mt |
0.462 |
|
| 2005 |
Sims RJ, Chen CF, Santos-Rosa H, Kouzarides T, Patel SS, Reinberg D. Human but not yeast CHD1 binds directly and selectively to histone H3 methylated at lysine 4 via its tandem chromodomains. The Journal of Biological Chemistry. 280: 41789-92. PMID 16263726 DOI: 10.1074/Jbc.C500395200 |
0.502 |
|
| 2005 |
Stimson L, Rowlands MG, Newbatt YM, Smith NF, Raynaud FI, Rogers P, Bavetsias V, Gorsuch S, Jarman M, Bannister A, Kouzarides T, McDonald E, Workman P, Aherne GW. Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity. Molecular Cancer Therapeutics. 4: 1521-32. PMID 16227401 DOI: 10.1158/1535-7163.Mct-05-0135 |
0.428 |
|
| 2005 |
Bannister AJ, Kouzarides T. Reversing histone methylation. Nature. 436: 1103-6. PMID 16121170 DOI: 10.1038/Nature04048 |
0.474 |
|
| 2005 |
Chavali GB, Ekblad CM, Basu BP, Brissett NC, Veprintsev D, Hughes-Davies L, Kouzarides T, Itzhaki LS, Doherty AJ. Crystal structure of the ENT domain of human EMSY. Journal of Molecular Biology. 350: 964-73. PMID 15978617 DOI: 10.1016/J.Jmb.2005.05.047 |
0.337 |
|
| 2005 |
Ekblad CM, Chavali GB, Basu BP, Freund SM, Veprintsev D, Hughes-Davies L, Kouzarides T, Doherty AJ, Itzhaki LS. Binding of EMSY to HP1beta: implications for recruitment of HP1beta and BS69. Embo Reports. 6: 675-80. PMID 15947784 DOI: 10.1038/Sj.Embor.7400415 |
0.349 |
|
| 2005 |
Bannister AJ, Schneider R, Myers FA, Thorne AW, Crane-Robinson C, Kouzarides T. Spatial distribution of di- and tri-methyl lysine 36 of histone H3 at active genes. The Journal of Biological Chemistry. 280: 17732-6. PMID 15760899 DOI: 10.1074/Jbc.M500796200 |
0.426 |
|
| 2005 |
Brenner C, Deplus R, Didelot C, Loriot A, Viré E, De Smet C, Gutierrez A, Danovi D, Bernard D, Boon T, Pelicci PG, Amati B, Kouzarides T, de Launoit Y, Di Croce L, et al. Myc represses transcription through recruitment of DNA methyltransferase corepressor. The Embo Journal. 24: 336-46. PMID 15616584 DOI: 10.1038/Sj.Emboj.7600509 |
0.495 |
|
| 2005 |
Bannister AJ, Kouzarides T. Differentiation and gene regulation Current Opinion in Genetics & Development. 15: 473-475. DOI: 10.1016/J.Gde.2005.08.008 |
0.349 |
|
| 2004 |
Sanders SL, Portoso M, Mata J, Bähler J, Allshire RC, Kouzarides T. Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage. Cell. 119: 603-14. PMID 15550243 DOI: 10.1016/J.Cell.2004.11.009 |
0.482 |
|
| 2004 |
Rodriguez C, Hughes-Davies L, Vallès H, Orsetti B, Cuny M, Ursule L, Kouzarides T, Theillet C. Amplification of the BRCA2 pathway gene EMSY in sporadic breast cancer is related to negative outcome. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 5785-91. PMID 15355907 DOI: 10.1158/1078-0432.Ccr-03-0410 |
0.323 |
|
| 2004 |
Cuthbert GL, Daujat S, Snowden AW, Erdjument-Bromage H, Hagiwara T, Yamada M, Schneider R, Gregory PD, Tempst P, Bannister AJ, Kouzarides T. Histone deimination antagonizes arginine methylation. Cell. 118: 545-53. PMID 15339660 DOI: 10.1016/J.Cell.2004.08.020 |
0.498 |
|
| 2004 |
Santos-Rosa H, Bannister AJ, Dehe PM, Géli V, Kouzarides T. Methylation of H3 lysine 4 at euchromatin promotes Sir3p association with heterochromatin. The Journal of Biological Chemistry. 279: 47506-12. PMID 15280381 DOI: 10.1074/Jbc.M407949200 |
0.47 |
|
| 2004 |
Schneider R, Bannister AJ, Weise C, Kouzarides T. Direct binding of INHAT to H3 tails disrupted by modifications Journal of Biological Chemistry. 279: 23859-23862. PMID 15100215 DOI: 10.1074/Jbc.C400151200 |
0.483 |
|
| 2004 |
Bannister AJ, Kouzarides T. Histone methylation: recognizing the methyl mark. Methods in Enzymology. 376: 269-88. PMID 14975312 DOI: 10.1016/S0076-6879(03)76018-2 |
0.467 |
|
| 2004 |
Kouzarides T. Functions of pRb and p53: what's the connection? Trends in Cell Biology. 5: 448-50. PMID 14732024 DOI: 10.1016/S0962-8924(00)89109-6 |
0.347 |
|
| 2004 |
Kouzarides T. Transcriptional regulation by the retinoblastoma protein. Trends in Cell Biology. 3: 211-3. PMID 14731754 DOI: 10.1016/0962-8924(93)90113-F |
0.43 |
|
| 2004 |
Schneider R, Bannister AJ, Myers FA, Thorne AW, Crane-Robinson C, Kouzarides T. Histone H3 lysine 4 methylation patterns in higher eukaryotic genes. Nature Cell Biology. 6: 73-7. PMID 14661024 DOI: 10.1038/Ncb1076 |
0.442 |
|
| 2004 |
Kouzarides T. Wellcome Trust Award Lecture. Chromatin-modifying enzymes in transcription and cancer. Biochemical Society Transactions. 31: 741-3. PMID 12887294 DOI: 10.1042/Bst0310741 |
0.433 |
|
| 2004 |
Schneider R, Bannister AJ, Myers FA, Thorne AW, Crane-Robinson C, Kouzarides T. Erratum: Errata: Histone H3 lysine 4 methylation patterns in higher eukaryotic genes Nature Cell Biology. 6: 465-465. DOI: 10.1038/Ncb1128 |
0.449 |
|
| 2003 |
Santos-Rosa H, Schneider R, Bernstein BE, Karabetsou N, Morillon A, Weise C, Schreiber SL, Mellor J, Kouzarides T. Methylation of histone H3 K4 mediates association of the Isw1p ATPase with chromatin Molecular Cell. 12: 1325-1332. PMID 14636589 DOI: 10.1016/S1097-2765(03)00438-6 |
0.496 |
|
| 2003 |
Barlev NA, Emelyanov AV, Castagnino P, Zegerman P, Bannister AJ, Sepulveda MA, Robert F, Tora L, Kouzarides T, Birshtein BK, Berger SL. A novel human Ada2 homologue functions with Gcn5 or Brg1 to coactivate transcription. Molecular and Cellular Biology. 23: 6944-57. PMID 12972612 DOI: 10.1128/Mcb.23.19.6944-6957.2003 |
0.481 |
|
| 2003 |
Erhardt S, Su IH, Schneider R, Barton S, Bannister AJ, Perez-Burgos L, Jenuwein T, Kouzarides T, Tarakhovsky A, Surani MA. Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development. Development (Cambridge, England). 130: 4235-48. PMID 12900441 DOI: 10.1242/Dev.00625 |
0.414 |
|
| 2003 |
Santos-Rosa H, Valls E, Kouzarides T, Martínez-Balbás M. Mechanisms of P/CAF auto-acetylation. Nucleic Acids Research. 31: 4285-92. PMID 12888487 DOI: 10.1093/Nar/Gkg655 |
0.366 |
|
| 2003 |
Fuks F, Hurd PJ, Deplus R, Kouzarides T. The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase Nucleic Acids Research. 31: 2305-2312. PMID 12711675 DOI: 10.1093/Nar/Gkg332 |
0.494 |
|
| 2003 |
Fuks F, Hurd PJ, Wolf D, Nan X, Bird AP, Kouzarides T. The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation Journal of Biological Chemistry. 278: 4035-4040. PMID 12427740 DOI: 10.1074/Jbc.M210256200 |
0.51 |
|
| 2002 |
Daujat S, Bauer UM, Shah V, Turner B, Berger S, Kouzarides T. Crosstalk between CARM1 methylation and CBP acetylation on histone H3. Current Biology : Cb. 12: 2090-7. PMID 12498683 DOI: 10.1016/S0960-9822(02)01387-8 |
0.519 |
|
| 2002 |
Partridge JF, Scott KS, Bannister AJ, Kouzarides T, Allshire RC. cis-acting DNA from fission yeast centromeres mediates histone H3 methylation and recruitment of silencing factors and cohesin to an ectopic site. Current Biology : Cb. 12: 1652-60. PMID 12361567 DOI: 10.1016/S0960-9822(02)01177-6 |
0.492 |
|
| 2002 |
Santos-Rosa H, Schneider R, Bannister AJ, Sherriff J, Bernstein BE, Emre NC, Schreiber SL, Mellor J, Kouzarides T. Active genes are tri-methylated at K4 of histone H3. Nature. 419: 407-11. PMID 12353038 DOI: 10.1038/Nature01080 |
0.445 |
|
| 2002 |
Deplus R, Brenner C, Burgers WA, Putmans P, Kouzarides T, de Launoit Y, Fuks F. Dnmt3L is a transcriptional repressor that recruits histone deacetylase. Nucleic Acids Research. 30: 3831-8. PMID 12202768 DOI: 10.1093/Nar/Gkf509 |
0.551 |
|
| 2002 |
Schneider R, Bannister AJ, Kouzarides T. Unsafe SETs: histone lysine methyltransferases and cancer. Trends in Biochemical Sciences. 27: 396-402. PMID 12151224 DOI: 10.1016/S0968-0004(02)02141-2 |
0.414 |
|
| 2002 |
Bannister AJ, Schneider R, Kouzarides T. Histone methylation: dynamic or static? Cell. 109: 801-6. PMID 12110177 DOI: 10.1016/S0092-8674(02)00798-5 |
0.513 |
|
| 2002 |
Arney KL, Bao S, Bannister AJ, Kouzarides T, Surani MA. Histone methylation defines epigenetic asymmetry in the mouse zygote. The International Journal of Developmental Biology. 46: 317-20. PMID 12068953 DOI: 10.1387/Ijdb.12068953 |
0.454 |
|
| 2002 |
Bernstein BE, Humphrey EL, Erlich RL, Schneider R, Bouman P, Liu JS, Kouzarides T, Schreiber SL. Methylation of histone H3 Lys 4 in coding regions of active genes. Proceedings of the National Academy of Sciences of the United States of America. 99: 8695-700. PMID 12060701 DOI: 10.1073/Pnas.082249499 |
0.51 |
|
| 2002 |
Burgers WA, Fuks F, Kouzarides T. DNA methyltransferases get connected to chromatin. Trends in Genetics : Tig. 18: 275-7. PMID 12044346 DOI: 10.1016/S0168-9525(02)02667-7 |
0.505 |
|
| 2002 |
Kirsh O, Seeler JS, Pichler A, Gast A, Müller S, Miska E, Mathieu M, Harel-Bellan A, Kouzarides T, Melchior F, Dejean A. The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase. The Embo Journal. 21: 2682-91. PMID 12032081 DOI: 10.1093/Emboj/21.11.2682 |
0.502 |
|
| 2002 |
Langley E, Pearson M, Faretta M, Bauer UM, Frye RA, Minucci S, Pelicci PG, Kouzarides T. Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence. The Embo Journal. 21: 2383-96. PMID 12006491 DOI: 10.1093/Emboj/21.10.2383 |
0.406 |
|
| 2002 |
Kouzarides T. Histone methylation in transcriptional control. Current Opinion in Genetics & Development. 12: 198-209. PMID 11893494 DOI: 10.1016/S0959-437X(02)00287-3 |
0.5 |
|
| 2002 |
Nielsen PR, Nietlispach D, Mott HR, Callaghan J, Bannister A, Kouzarides T, Murzin AG, Murzina NV, Laue ED. Structure of the HP1 chromodomain bound to histone H3 methylated at lysine 9. Nature. 416: 103-7. PMID 11882902 DOI: 10.1038/Nature722 |
0.48 |
|
| 2002 |
Zegerman P, Canas B, Pappin D, Kouzarides T. Histone H3 lysine 4 methylation disrupts binding of nucleosome remodeling and deacetylase (NuRD) repressor complex. The Journal of Biological Chemistry. 277: 11621-4. PMID 11850414 DOI: 10.1074/Jbc.C200045200 |
0.508 |
|
| 2002 |
Di Croce L, Raker VA, Corsaro M, Fazi F, Fanelli M, Faretta M, Fuks F, Lo Coco F, Kouzarides T, Nervi C, Minucci S, Pelicci PG. Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science (New York, N.Y.). 295: 1079-82. PMID 11834837 DOI: 10.1126/Science.1065173 |
0.468 |
|
| 2002 |
Bauer UM, Daujat S, Nielsen SJ, Nightingale K, Kouzarides T. Methylation at arginine 17 of histone H3 is linked to gene activation. Embo Reports. 3: 39-44. PMID 11751582 DOI: 10.1093/Embo-Reports/Kvf013 |
0.469 |
|
| 2002 |
Turlais F, Hardcastle A, Rowlands M, Newbatt Y, Bannister A, Kouzarides T, Workman P, Aherne GW. High-throughput screening for identification of small molecule inhibitors of histone acetyltransferases using scintillating microplates (FlashPlate). Analytical Biochemistry. 298: 62-8. PMID 11673896 DOI: 10.1006/Abio.2001.5340 |
0.439 |
|
| 2001 |
Miska EA, Langley E, Wolf D, Karlsson C, Pines J, Kouzarides T. Differential localization of HDAC4 orchestrates muscle differentiation. Nucleic Acids Research. 29: 3439-47. PMID 11504882 DOI: 10.1093/Nar/29.16.3439 |
0.426 |
|
| 2001 |
Nielsen SJ, Schneider R, Bauer UM, Bannister AJ, Morrison A, O'Carroll D, Firestein R, Cleary M, Jenuwein T, Herrera RE, Kouzarides T. Rb targets histone H3 methylation and HP1 to promoters. Nature. 412: 561-5. PMID 11484059 DOI: 10.1038/35087620 |
0.532 |
|
| 2001 |
Fuks F, Burgers WA, Godin N, Kasai M, Kouzarides T. Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription. The Embo Journal. 20: 2536-44. PMID 11350943 DOI: 10.1093/Emboj/20.10.2536 |
0.527 |
|
| 2001 |
Yang SH, Vickers E, Brehm A, Kouzarides T, Sharrocks AD. Temporal recruitment of the mSin3A-histone deacetylase corepressor complex to the ETS domain transcription factor Elk-1. Molecular and Cellular Biology. 21: 2802-14. PMID 11283259 DOI: 10.1128/Mcb.21.8.2802-2814.2001 |
0.467 |
|
| 2001 |
Takei Y, Swietlik M, Tanoue A, Tsujimoto G, Kouzarides T, Laskey R. MCM3AP, a novel acetyltransferase that acetylates replication protein MCM3 Embo Reports. 2: 119-123. PMID 11258703 DOI: 10.1093/Embo-Reports/Kve026 |
0.445 |
|
| 2001 |
Bannister AJ, Zegerman P, Partridge JF, Miska EA, Thomas JO, Allshire RC, Kouzarides T. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature. 410: 120-4. PMID 11242054 DOI: 10.1038/35065138 |
0.502 |
|
| 2000 |
Milner J, Fuks F, Hughes-Davies L, Kouzarides T. The BRCA2 activation domain associates with and is phosphorylated by a cellular protein kinase. Oncogene. 19: 4441-5. PMID 10980621 DOI: 10.1038/Sj.Onc.1203793 |
0.357 |
|
| 2000 |
Bryant LA, Mixon P, Davidson M, Bannister AJ, Kouzarides T, Sinclair JH. The human cytomegalovirus 86-kilodalton major immediate-early protein interacts physically and functionally with histone acetyltransferase P/CAF. Journal of Virology. 74: 7230-7. PMID 10906177 DOI: 10.1128/Jvi.74.16.7230-7237.2000 |
0.488 |
|
| 2000 |
Bannister AJ, Miska EA, Görlich D, Kouzarides T. Acetylation of importin-alpha nuclear import factors by CBP/p300. Current Biology : Cb. 10: 467-70. PMID 10801418 DOI: 10.1016/S0960-9822(00)00445-0 |
0.459 |
|
| 2000 |
Lutz M, Burke LJ, Barreto G, Goeman F, Greb H, Arnold R, Schultheiss H, Brehm A, Kouzarides T, Lobanenkov V, Renkawitz R. Transcriptional repression by the insulator protein CTCF involves histone deacetylases. Nucleic Acids Research. 28: 1707-13. PMID 10734189 DOI: 10.1093/Nar/28.8.1707 |
0.513 |
|
| 2000 |
Grimes JA, Nielsen SJ, Battaglioli E, Miska EA, Speh JC, Berry DL, Atouf F, Holdener BC, Mandel G, Kouzarides T. The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex. The Journal of Biological Chemistry. 275: 9461-7. PMID 10734093 DOI: 10.1074/Jbc.275.13.9461 |
0.374 |
|
| 2000 |
Kouzarides T. Acetylation: a regulatory modification to rival phosphorylation? The Embo Journal. 19: 1176-9. PMID 10716917 DOI: 10.1093/Emboj/19.6.1176 |
0.473 |
|
| 2000 |
Gayther SA, Batley SJ, Linger L, Bannister A, Thorpe K, Chin SF, Daigo Y, Russell P, Wilson A, Sowter HM, Delhanty JDA, Ponder BAJ, Kouzarides T, Caldas C. Mutations truncating the EP300 acetylase in human cancers Nature Genetics. 24: 300-303. PMID 10700188 DOI: 10.1038/73536 |
0.324 |
|
| 2000 |
Martínez-Balbás MA, Bauer UM, Nielsen SJ, Brehm A, Kouzarides T. Regulation of E2F1 activity by acetylation. The Embo Journal. 19: 662-71. PMID 10675335 DOI: 10.1093/Emboj/19.4.662 |
0.477 |
|
| 2000 |
Zegerman P, Bannister AJ, Kouzarides T. The putative tumour suppressor Fus-2 is an N-acetyltransferase. Oncogene. 19: 161-3. PMID 10644992 DOI: 10.1038/Sj.Onc.1203234 |
0.366 |
|
| 2000 |
Huang EY, Zhang J, Miska EA, Guenther MG, Kouzarides T, Lazar MA. Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway. Genes & Development. 14: 45-54. PMID 10640275 |
0.323 |
|
| 2000 |
Fuks F, Burgers WA, Brehm A, Hughes-Davies L, Kouzarides T. DNA methyltransferase Dnmt1 associates with histone deacetylase activity. Nature Genetics. 24: 88-91. PMID 10615135 DOI: 10.1038/71750 |
0.521 |
|
| 2000 |
Huang EY, Zhang J, Miska EA, Guenther MG, Kouzarides T, Lazar MA. Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway Genes & Development. 14: 45-54. DOI: 10.1101/Gad.14.1.45 |
0.432 |
|
| 1999 |
Miska EA, Karlsson C, Langley E, Nielsen SJ, Pines J, Kouzarides T. HDAC4 deacetylase associates with and represses the MEF2 transcription factor. The Embo Journal. 18: 5099-107. PMID 10487761 DOI: 10.1093/Emboj/18.18.5099 |
0.502 |
|
| 1999 |
Sparrow DB, Miska EA, Langley E, Reynaud-Deonauth S, Kotecha S, Towers N, Spohr G, Kouzarides T, Mohun TJ. MEF-2 function is modified by a novel co-repressor, MITR. The Embo Journal. 18: 5085-98. PMID 10487760 DOI: 10.1093/Emboj/18.18.5085 |
0.444 |
|
| 1999 |
Vandel L, Kouzarides T. Residues phosphorylated by TFIIH are required for E2F-1 degradation during S-phase. The Embo Journal. 18: 4280-91. PMID 10428966 DOI: 10.1093/Emboj/18.15.4280 |
0.363 |
|
| 1999 |
Avots A, Buttmann M, Chuvpilo S, Escher C, Smola U, Bannister AJ, Rapp UR, Kouzarides T, Serfling E. CBP/p300 integrates Raf/Rac-signaling pathways in the transcriptional induction of NF-ATc during T cell activation. Immunity. 10: 515-24. PMID 10367897 DOI: 10.1016/S1074-7613(00)80051-5 |
0.377 |
|
| 1999 |
Radkov SA, Touitou R, Brehm A, Rowe M, West M, Kouzarides T, Allday MJ. Epstein-Barr virus nuclear antigen 3C interacts with histone deacetylase to repress transcription. Journal of Virology. 73: 5688-97. PMID 10364319 DOI: 10.1128/Jvi.73.7.5688-5697.1999 |
0.526 |
|
| 1999 |
Brehm A, Kouzarides T. Retinoblastoma protein meets chromatin. Trends in Biochemical Sciences. 24: 142-5. PMID 10322419 DOI: 10.1016/S0968-0004(99)01368-7 |
0.512 |
|
| 1999 |
Brehm A, Nielsen SJ, Miska EA, McCance DJ, Reid JL, Bannister AJ, Kouzarides T. The E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growth. The Embo Journal. 18: 2449-58. PMID 10228159 DOI: 10.1093/Emboj/18.9.2449 |
0.405 |
|
| 1999 |
O'Connor MJ, Zimmermann H, Nielsen S, Bernard HU, Kouzarides T. Characterization of an E1A-CBP interaction defines a novel transcriptional adapter motif (TRAM) in CBP/p300. Journal of Virology. 73: 3574-81. PMID 10196247 DOI: 10.1128/Jvi.73.5.3574-3581.1999 |
0.408 |
|
| 1999 |
Kouzarides T. Histone acetylases and deacetylases in cell proliferation. Current Opinion in Genetics & Development. 9: 40-8. PMID 10072350 DOI: 10.1016/S0959-437X(99)80006-9 |
0.47 |
|
| 1998 |
Fuks F, Milner J, Kouzarides T. BRCA2 associates with acetyltransferase activity when bound to P/CAF. Oncogene. 17: 2531-4. PMID 9824164 DOI: 10.1038/Sj.Onc.1202475 |
0.45 |
|
| 1998 |
Reid JL, Bannister AJ, Zegerman P, Martínez-Balbás MA, Kouzarides T. E1A directly binds and regulates the P/CAF acetyltransferase. The Embo Journal. 17: 4469-77. PMID 9687513 DOI: 10.1093/Emboj/17.15.4469 |
0.422 |
|
| 1998 |
Vallian S, Gäken JA, Gingold EB, Kouzarides T, Chang KS, Farzaneh F. Modulation of Fos-mediated AP-1 transcription by the promyelocytic leukemia protein. Oncogene. 16: 2843-53. PMID 9671405 DOI: 10.1038/Sj.Onc.1201837 |
0.389 |
|
| 1998 |
Huntley R, Healy S, Freeman D, Lavender P, de Jager S, Greenwood J, Makker J, Walker E, Jackman M, Xie Q, Bannister AJ, Kouzarides T, Gutiérrez C, Doonan JH, Murray JA. The maize retinoblastoma protein homologue ZmRb-1 is regulated during leaf development and displays conserved interactions with G1/S regulators and plant cyclin D (CycD) proteins. Plant Molecular Biology. 37: 155-69. PMID 9620273 DOI: 10.1023/A:1005902226256 |
0.346 |
|
| 1998 |
Martinez-Balbás MA, Bannister AJ, Martin K, Haus-Seuffert P, Meisterernst M, Kouzarides T. The acetyltransferase activity of CBP stimulates transcription. The Embo Journal. 17: 2886-93. PMID 9582282 DOI: 10.1093/Emboj/17.10.2886 |
0.486 |
|
| 1998 |
Brehm A, Miska EA, McCance DJ, Reid JL, Bannister AJ, Kouzarides T. Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature. 391: 597-601. PMID 9468139 DOI: 10.1038/35404 |
0.538 |
|
| 1998 |
Vallian S, Gäken JA, Trayner ID, Gingold EB, Kouzarides T, Chang KS, Farzaneh F. Transcriptional repression by the promyelocytic leukemia protein, PML. Experimental Cell Research. 237: 371-82. PMID 9434633 DOI: 10.1006/Excr.1997.3801 |
0.434 |
|
| 1998 |
Morkel M, Wenkel J, Bannister AJ, Kouzarides T, Hagemeier C. An E2F-like repressor of transcription. Nature. 390: 567-8. PMID 9403682 DOI: 10.1038/37507 |
0.443 |
|
| 1997 |
Trouche D, Le Chalony C, Muchardt C, Yaniv M, Kouzarides T. RB and hbrm cooperate to repress the activation functions of E2F1. Proceedings of the National Academy of Sciences of the United States of America. 94: 11268-73. PMID 9326598 DOI: 10.1073/Pnas.94.21.11268 |
0.421 |
|
| 1997 |
Hsieh JK, Fredersdorf S, Kouzarides T, Martin K, Lu X. E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction. Genes & Development. 11: 1840-52. PMID 9242491 DOI: 10.1101/Gad.11.14.1840 |
0.314 |
|
| 1997 |
Sato S, Roberts K, Gambino G, Cook A, Kouzarides T, Goding CR. CBP/p300 as a co-factor for the Microphthalmia transcription factor. Oncogene. 14: 3083-92. PMID 9223672 DOI: 10.1038/Sj.Onc.1201298 |
0.436 |
|
| 1997 |
Lavender P, Vandel L, Bannister AJ, Kouzarides T. The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A. Oncogene. 14: 2721-8. PMID 9178770 DOI: 10.1038/Sj.Onc.1201243 |
0.398 |
|
| 1997 |
Larminie CG, Cairns CA, Mital R, Martin K, Kouzarides T, Jackson SP, White RJ. Mechanistic analysis of RNA polymerase III regulation by the retinoblastoma protein. The Embo Journal. 16: 2061-71. PMID 9155032 DOI: 10.1093/Emboj/16.8.2061 |
0.423 |
|
| 1997 |
Milner J, Ponder B, Hughes-Davies L, Seltmann M, Kouzarides T. Transcriptional activation functions in BRCA2. Nature. 386: 772-3. PMID 9126734 DOI: 10.1038/386772A0 |
0.379 |
|
| 1997 |
Bannister AJ, Kouzarides T. The CBP co-activator is a histone acetyltransferase. Nature. 384: 641-3. PMID 8967953 DOI: 10.1038/384641A0 |
0.487 |
|
| 1996 |
Mizzen CA, Yang XJ, Kokubo T, Brownell JE, Bannister AJ, Owen-Hughes T, Workman J, Wang L, Berger SL, Kouzarides T, Nakatani Y, Allis CD. The TAF(II)250 subunit of TFIID has histone acetyltransferase activity Cell. 87: 1261-1270. PMID 8980232 DOI: 10.1016/S0092-8674(00)81821-8 |
0.443 |
|
| 1996 |
Trouche D, Cook A, Kouzarides T. The CBP co-activator stimulates E2F1/DP1 activity. Nucleic Acids Research. 24: 4139-45. PMID 8932363 DOI: 10.1093/Nar/24.21.4139 |
0.388 |
|
| 1996 |
White RJ, Trouche D, Martin K, Jackson SP, Kouzarides T. Repression of RNA polymerase III transcription by the retinoblastoma protein. Nature. 382: 88-90. PMID 8657311 DOI: 10.1038/382088A0 |
0.403 |
|
| 1996 |
Trouche D, Kouzarides T. E2F1 and E1A(12S) have a homologous activation domain regulated by RB and CBP. Proceedings of the National Academy of Sciences of the United States of America. 93: 1439-42. PMID 8643650 DOI: 10.1073/Pnas.93.4.1439 |
0.364 |
|
| 1995 |
Martin K, Trouche D, Hagemeier C, Kouzarides T. Regulation of transcription by E2F1/DP1. Journal of Cell Science. Supplement. 19: 91-4. PMID 8655653 DOI: 10.1242/Jcs.1995.Supplement_19.13 |
0.443 |
|
| 1995 |
Martin K, Trouche D, Hagemeier C, Sørensen TS, La Thangue NB, Kouzarides T. Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein. Nature. 375: 691-4. PMID 7791903 DOI: 10.1038/375691A0 |
0.388 |
|
| 1995 |
Kouzarides T. Transcriptional control by the retinoblastoma protein. Seminars in Cancer Biology. 6: 91-8. PMID 7647311 DOI: 10.1006/Scbi.1995.0012 |
0.412 |
|
| 1995 |
Brown H, Sutherland J, Cook A, Bannister A, Kouzarides T. An inhibitor domain in c-Fos regulates activation domains containing the HOB1 motif. The Embo Journal. 14: 124-131. DOI: 10.1002/J.1460-2075.1995.Tb06982.X |
0.336 |
|
| 1995 |
Bannister AJ, Kouzarides T. CBP-induced stimulation of c-Fos activity is abrogated by E1A. The Embo Journal. 14: 4758-4762. DOI: 10.1002/J.1460-2075.1995.Tb00157.X |
0.37 |
|
| 1994 |
Caswell R, Hagemeier C, Chiou CJ, Hayward G, Kouzarides T, Sinclair J. The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulation. The Journal of General Virology. 2691-8. PMID 8277274 DOI: 10.1099/0022-1317-74-12-2691 |
0.401 |
|
| 1994 |
Hagemeier C, Cook A, Kouzarides T. The retinoblastoma protein binds E2F residues required for activation in vivo and TBP binding in vitro. Nucleic Acids Research. 21: 4998-5004. PMID 8255752 DOI: 10.1093/Nar/21.22.4998 |
0.394 |
|
| 1994 |
Gibson TJ, Thompson JD, Blocker A, Kouzarides T. Evidence for a protein domain superfamily shared by the cyclins, TFIIB and RB/p107. Nucleic Acids Research. 22: 946-52. PMID 8152925 DOI: 10.1093/Nar/22.6.946 |
0.344 |
|
| 1994 |
Metz R, Bannister AJ, Sutherland JA, Hagemeier C, O'Rourke EC, Cook A, Bravo R, Kouzarides T. c-Fos-induced activation of a TATA-box-containing promoter involves direct contact with TATA-box-binding protein. Molecular and Cellular Biology. 14: 6021-9. PMID 8065335 DOI: 10.1128/Mcb.14.9.6021 |
0.399 |
|
| 1994 |
Bannister AJ, Brown HJ, Sutherland JA, Kouzarides T. Phosphorylation of the c-Fos and c-Jun HOB1 motif stimulates its activation capacity. Nucleic Acids Research. 22: 5173-6. PMID 7816602 DOI: 10.1093/Nar/22.24.5173 |
0.308 |
|
| 1994 |
Metz R, Kouzarides T, Bravo R. A C-terminal domain in FosB, absent in FosB/SF and Fra-1, which is able to interact with the TATA binding protein, is required for altered cell growth. The Embo Journal. 13: 3832-3842. DOI: 10.1002/J.1460-2075.1994.Tb06694.X |
0.423 |
|
| 1994 |
Hagemeier C, Caswell R, Hayhurst G, Sinclair J, Kouzarides T. Functional interaction between the HCMV IE2 transactivator and the retinoblastoma protein. The Embo Journal. 13: 2897-2903. DOI: 10.1002/J.1460-2075.1994.Tb06584.X |
0.423 |
|
| 1993 |
Bannister AJ, Gottlieb TM, Kouzarides T, Jackson SP. c-Jun is phosphorylated by the DNA-dependent protein kinase in vitro; definition of the minimal kinase recognition motif. Nucleic Acids Research. 21: 1289-95. PMID 8464713 DOI: 10.1093/Nar/21.5.1289 |
0.333 |
|
| 1993 |
Hagemeier C, Bannister AJ, Cook A, Kouzarides T. The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB. Proceedings of the National Academy of Sciences of the United States of America. 90: 1580-4. PMID 8434021 DOI: 10.1073/Pnas.90.4.1580 |
0.38 |
|
| 1993 |
Frampton J, Kouzarides T, Döderlein G, Graf T, Weston K. Influence of the v-Myb transactivation domain on the oncoprotein's transformation specificity. The Embo Journal. 12: 1333-1341. DOI: 10.1002/J.1460-2075.1993.Tb05778.X |
0.302 |
|
| 1992 |
Sutherland JA, Cook A, Bannister AJ, Kouzarides T. Conserved motifs in Fos and Jun define a new class of activation domain. Genes & Development. 6: 1810-9. PMID 1516835 DOI: 10.1101/Gad.6.9.1810 |
0.381 |
|
| 1992 |
Hagemeier C, Walker S, Caswell R, Kouzarides T, Sinclair J. The human cytomegalovirus 80-kilodalton but not the 72-kilodalton immediate-early protein transactivates heterologous promoters in a TATA box-dependent mechanism and interacts directly with TFIID. Journal of Virology. 66: 4452-6. PMID 1318414 DOI: 10.1128/Jvi.66.7.4452-4456.1992 |
0.36 |
|
| 1991 |
Bankier AT, Beck S, Bohni R, Brown CM, Cerny R, Chee MS, Hutchison CA, Kouzarides T, Martignetti JA, Preddie E, Satchwell SC, Tomlinson P, Weston KM, Barrell BG. The DNA sequence of the human cytomegalovirus genome Dna Sequence : the Journal of Dna Sequencing and Mapping. 2: 1-12. PMID 1666311 DOI: 10.3109/10425179109008433 |
0.307 |
|
| 1989 |
Kouzarides T, Ziff E. Leucine zippers of fos, jun and GCN4 dictate dimerization specificity and thereby control DNA binding. Nature. 340: 568-71. PMID 2505081 DOI: 10.1038/340568A0 |
0.372 |
|
| 1989 |
Farrell PJ, Rowe DT, Rooney CM, Kouzarides T. Epstein-Barr virus BZLF1 trans-activator specifically binds to a consensus AP-1 site and is related to c-fos. The Embo Journal. 8: 127-132. DOI: 10.1002/J.1460-2075.1989.Tb03356.X |
0.34 |
|
| 1988 |
Metz R, Gorham J, Siegfried Z, Leonard D, Gizang-Ginsberg E, Thompson MA, Lawe D, Kouzarides T, Vosatka R, MacGregor D, Jamal S, Greenberg ME, Ziff EB. Gene regulation by growth factors Cold Spring Harbor Symposia On Quantitative Biology. 53: 727-737. PMID 3254783 DOI: 10.1101/Sqb.1988.053.01.083 |
0.304 |
|
| 1988 |
Kouzarides T, Ziff E. The role of the leucine zipper in the fos-jun interaction. Nature. 336: 646-51. PMID 2974122 DOI: 10.1038/336646A0 |
0.336 |
|
| 1988 |
Kouzarides T, Bankier AT, Satchwell SC, Preddy E, Barrell BG. An immediate early gene of human cytomegalovirus encodes a potential membrane glycoprotein. Virology. 165: 151-64. PMID 2838954 DOI: 10.1016/0042-6822(88)90668-X |
0.359 |
|
| 1987 |
Jahn G, Kouzarides T, Mach M, Scholl BC, Plachter B, Traupe B, Preddie E, Satchwell SC, Fleckenstein B, Barrell BG. Map position and nucleotide sequence of the gene for the large structural phosphoprotein of human cytomegalovirus. Journal of Virology. 61: 1358-67. PMID 3033266 DOI: 10.1128/Jvi.61.5.1358-1367.1987 |
0.35 |
|
| 1987 |
Kouzarides T, Bankier AT, Satchwell SC, Weston K, Tomlinson P, Barrell BG. Large-scale rearrangement of homologous regions in the genomes of HCMV and EBV. Virology. 157: 397-413. PMID 3029980 DOI: 10.1016/0042-6822(87)90282-0 |
0.327 |
|
| 1987 |
Kouzarides T, Bankier AT, Satchwell SC, Weston K, Tomlinson P, Barrell BG. Sequence and transcription analysis of the human cytomegalovirus DNA polymerase gene. Journal of Virology. 61: 125-33. PMID 3023690 DOI: 10.1128/Jvi.61.1.125-133.1987 |
0.333 |
|
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