| Year |
Citation |
Score |
| 2023 |
Haghani A, Li CZ, Robeck TR, Zhang J, Lu AT, Ablaeva J, Acosta-Rodríguez VA, Adams DM, Alagaili AN, Almunia J, Aloysius A, Amor NMS, Ardehali R, Arneson A, Baker CS, ... ... Niehrs C, et al. DNA methylation networks underlying mammalian traits. Science (New York, N.Y.). 381: eabq5693. PMID 37561875 DOI: 10.1126/science.abq5693 |
0.462 |
|
| 2023 |
Da Silva F, Niehrs C. Multimodal Wnt signalling in the mouse neocortex. Cells & Development. 174: 203838. PMID 37060946 DOI: 10.1016/j.cdev.2023.203838 |
0.318 |
|
| 2023 |
Zhang K, Da Silva F, Seidl C, Wilsch-Bräuninger M, Herbst J, Huttner WB, Niehrs C. Primary cilia are WNT-transducing organelles whose biogenesis is controlled by a WNT-PP1 axis. Developmental Cell. 58: 139-154.e8. PMID 36693320 DOI: 10.1016/j.devcel.2022.12.006 |
0.543 |
|
| 2021 |
Niehrs C. The role of Xenopus developmental biology in unraveling Wnt signalling and antero-posterior axis formation. Developmental Biology. 482: 1-6. PMID 34818531 DOI: 10.1016/j.ydbio.2021.11.006 |
0.308 |
|
| 2021 |
Da Silva F, Zhang K, Pinson A, Fatti E, Wilsch-Bräuninger M, Herbst J, Vidal V, Schedl A, Huttner WB, Niehrs C. Mitotic WNT signalling orchestrates neurogenesis in the developing neocortex. The Embo Journal. e108041. PMID 34431536 DOI: 10.15252/embj.2021108041 |
0.541 |
|
| 2020 |
Chang LS, Kim M, Glinka A, Reinhard C, Niehrs C. The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer. Elife. 9. PMID 31934854 DOI: 10.7554/Elife.51248 |
0.425 |
|
| 2020 |
Holstein T, Niehrs C. Decision letter: Wnt/β-catenin signaling is an evolutionarily conserved determinant of chordate dorsal organizer Elife. DOI: 10.7554/Elife.56817.Sa1 |
0.324 |
|
| 2020 |
Niehrs C, Langhe SD. Decision letter: A novel function of R-spondin1 in regulating estrogen receptor expression independent of Wnt/β-catenin signaling Elife. DOI: 10.7554/Elife.56434.Sa1 |
0.359 |
|
| 2019 |
Schüle KM, Leichsenring M, Andreani T, Vastolo V, Mallick M, Musheev MU, Karaulanov E, Niehrs C. GADD45 promotes locus-specific DNA demethylation and 2C cycling in embryonic stem cells. Genes & Development. PMID 31171699 DOI: 10.1101/Gad.325696.119 |
0.377 |
|
| 2018 |
Melnik S, Dvornikov D, Müller-Decker K, Depner S, Stannek P, Meister M, Warth A, Thomas M, Muley T, Risch A, Plass C, Klingmüller U, Niehrs C, Glinka A. Cancer cell specific inhibition of Wnt/β-catenin signaling by forced intracellular acidification. Cell Discovery. 4: 37. PMID 29977599 DOI: 10.1038/S41421-018-0033-2 |
0.347 |
|
| 2017 |
Martins LR, Bung RK, Koch S, Richter K, Schwarzmüller L, Terhardt D, Kurtulmus B, Niehrs C, Rouhi A, Lohmann I, Pereira G, Fröhling S, Glimm H, Scholl C. Stk33 is required for spermatid differentiation and male fertility in mice. Developmental Biology. PMID 29155043 DOI: 10.1016/J.Ydbio.2017.11.007 |
0.332 |
|
| 2017 |
Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C. Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover. Developmental Cell. 43: 71-82.e6. PMID 29017031 DOI: 10.1016/J.Devcel.2017.09.011 |
0.608 |
|
| 2017 |
Knuckles P, Carl SH, Musheev M, Niehrs C, Wenger A, Bühler M. RNA fate determination through cotranscriptional adenosine methylation and microprocessor binding. Nature Structural & Molecular Biology. PMID 28581511 DOI: 10.1038/Nsmb.3419 |
0.325 |
|
| 2017 |
Berger BS, Acebron SP, Herbst J, Koch S, Niehrs C. Parkinson's disease-associated receptor GPR37 is an ER chaperone for LRP6. Embo Reports. PMID 28341812 DOI: 10.15252/Embr.201643585 |
0.401 |
|
| 2016 |
Acebron SP, Niehrs C. β-Catenin-Independent Roles of Wnt/LRP6 Signaling. Trends in Cell Biology. 26: 956-967. PMID 27568239 DOI: 10.1016/J.Tcb.2016.07.009 |
0.379 |
|
| 2016 |
Boutros M, Niehrs C. Sticking Around: Short-Range Activity of Wnt Ligands. Developmental Cell. 36: 485-6. PMID 26954543 DOI: 10.1016/J.Devcel.2016.02.018 |
0.331 |
|
| 2016 |
Scholz B, Korn C, Wojtarowicz J, Mogler C, Augustin I, Boutros M, Niehrs C, Augustin HG. Endothelial RSPO3 Controls Vascular Stability and Pruning through Non-canonical WNT/Ca(2+)/NFAT Signaling. Developmental Cell. 36: 79-93. PMID 26766444 DOI: 10.1016/J.Devcel.2015.12.015 |
0.327 |
|
| 2015 |
Koch S, Acebron SP, Herbst J, Hatiboglu G, Niehrs C. Post-transcriptional Wnt Signaling Governs Epididymal Sperm Maturation. Cell. 163: 1225-36. PMID 26590424 DOI: 10.1016/J.Cell.2015.10.029 |
0.429 |
|
| 2015 |
Kienhöfer S, Musheev MU, Stapf U, Helm M, Schomacher L, Niehrs C, Schäfer A. GADD45a physically and functionally interacts with TET1. Differentiation; Research in Biological Diversity. PMID 26546041 DOI: 10.1016/J.Diff.2015.10.003 |
0.311 |
|
| 2015 |
Blum M, De Robertis EM, Wallingford JB, Niehrs C. Morpholinos: Antisense and Sensibility. Developmental Cell. 35: 145-9. PMID 26506304 DOI: 10.1016/J.Devcel.2015.09.017 |
0.666 |
|
| 2015 |
Fukusumi Y, Meier F, Götz S, Matheus F, Irmler M, Beckervordersandforth R, Faus-Kessler T, Minina E, Rauser B, Zhang J, Arenas E, Andersson E, Niehrs C, Beckers J, Simeone A, et al. Dickkopf 3 Promotes the Differentiation of a Rostrolateral Midbrain Dopaminergic Neuronal Subset In Vivo and from Pluripotent Stem Cells In Vitro in the Mouse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13385-401. PMID 26424886 DOI: 10.1523/Jneurosci.1722-15.2015 |
0.564 |
|
| 2015 |
Kimura-Yoshida C, Mochida K, Ellwanger K, Niehrs C, Matsuo I. Fate Specification of Neural Plate Border by Canonical Wnt Signaling and Grhl3 is Crucial for Neural Tube Closure. Ebiomedicine. 2: 513-27. PMID 26288816 DOI: 10.1016/J.Ebiom.2015.04.012 |
0.337 |
|
| 2015 |
Welling M, Chen HH, Muñoz J, Musheev MU, Kester L, Junker JP, Mischerikow N, Arbab M, Kuijk E, Silberstein L, Kharchenko PV, Geens M, Niehrs C, van de Velde H, van Oudenaarden A, et al. DAZL regulates Tet1 translation in murine embryonic stem cells. Embo Reports. PMID 26077710 DOI: 10.15252/Embr.201540538 |
0.351 |
|
| 2015 |
Huang YL, Anvarian Z, Döderlein G, Acebron SP, Niehrs C. Maternal Wnt/STOP signaling promotes cell division during early Xenopus embryogenesis. Proceedings of the National Academy of Sciences of the United States of America. 112: 5732-7. PMID 25901317 DOI: 10.1073/Pnas.1423533112 |
0.43 |
|
| 2014 |
De Robertis EM, Niehrs C. Herbert Steinbeisser: a life with the Xenopus embryo. The International Journal of Developmental Biology. 58: 299-302. PMID 25354448 DOI: 10.1387/Ijdb.140117Ed |
0.481 |
|
| 2014 |
Arab K, Park YJ, Lindroth AM, Schäfer A, Oakes C, Weichenhan D, Lukanova A, Lundin E, Risch A, Meister M, Dienemann H, Dyckhoff G, Herold-Mende C, Grummt I, Niehrs C, et al. Long noncoding RNA TARID directs demethylation and activation of the tumor suppressor TCF21 via GADD45A. Molecular Cell. 55: 604-14. PMID 25087872 DOI: 10.1016/J.Molcel.2014.06.031 |
0.335 |
|
| 2014 |
Simonetti M, Agarwal N, Stösser S, Bali KK, Karaulanov E, Kamble R, Pospisilova B, Kurejova M, Birchmeier W, Niehrs C, Heppenstall P, Kuner R. Wnt-Fzd signaling sensitizes peripheral sensory neurons via distinct noncanonical pathways. Neuron. 83: 104-21. PMID 24991956 DOI: 10.1016/J.Neuron.2014.05.037 |
0.369 |
|
| 2014 |
Acebron SP, Karaulanov E, Berger BS, Huang YL, Niehrs C. Mitotic wnt signaling promotes protein stabilization and regulates cell size. Molecular Cell. 54: 663-74. PMID 24837680 DOI: 10.1016/J.Molcel.2014.04.014 |
0.408 |
|
| 2014 |
Huang YL, Niehrs C. Polarized Wnt signaling regulates ectodermal cell fate in Xenopus. Developmental Cell. 29: 250-7. PMID 24780739 DOI: 10.1016/J.Devcel.2014.03.015 |
0.384 |
|
| 2013 |
Demir K, Kirsch N, Beretta CA, Erdmann G, Ingelfinger D, Moro E, Argenton F, Carl M, Niehrs C, Boutros M. RAB8B is required for activity and caveolar endocytosis of LRP6. Cell Reports. 4: 1224-34. PMID 24035388 DOI: 10.1016/J.Celrep.2013.08.008 |
0.431 |
|
| 2013 |
Cruciat CM, Dolde C, de Groot RE, Ohkawara B, Reinhard C, Korswagen HC, Niehrs C. RNA helicase DDX3 is a regulatory subunit of casein kinase 1 in Wnt-β-catenin signaling. Science (New York, N.Y.). 339: 1436-41. PMID 23413191 DOI: 10.1126/Science.1231499 |
0.344 |
|
| 2013 |
Seib DR, Corsini NS, Ellwanger K, Plaas C, Mateos A, Pitzer C, Niehrs C, Celikel T, Martin-Villalba A. Loss of Dickkopf-1 restores neurogenesis in old age and counteracts cognitive decline. Cell Stem Cell. 12: 204-14. PMID 23395445 DOI: 10.1016/J.Stem.2012.11.010 |
0.323 |
|
| 2013 |
Cruciat CM, Niehrs C. Secreted and transmembrane wnt inhibitors and activators. Cold Spring Harbor Perspectives in Biology. 5: a015081. PMID 23085770 DOI: 10.1101/Cshperspect.A015081 |
0.408 |
|
| 2013 |
Kawano Y, Romero D, Bengora N, Walker M, Eto M, Waxman J, Niehrs C, Kypta R. 802 LOSS OF DICKKOPF-3 EXPRESSION IMPAIRS PROSTATE ACINAR MORPHOGENESIS VIA ABERRANT TGF-β/SMAD SIGNALLING ACTIVATION Journal of Urology. 189. DOI: 10.1016/J.Juro.2013.02.366 |
0.325 |
|
| 2012 |
Niehrs C. The complex world of WNT receptor signalling. Nature Reviews. Molecular Cell Biology. 13: 767-79. PMID 23151663 DOI: 10.1038/Nrm3470 |
0.316 |
|
| 2012 |
Gierl MS, Gruhn WH, von Seggern A, Maltry N, Niehrs C. GADD45G functions in male sex determination by promoting p38 signaling and Sry expression. Developmental Cell. 23: 1032-42. PMID 23102581 DOI: 10.1016/J.Devcel.2012.09.014 |
0.387 |
|
| 2012 |
El wakil A, Bandulik S, Guy N, Bendahhou S, Zennaro MC, Niehrs C, Mari B, Warth R, Barhanin J, Lalli E. Dkk3 is a component of the genetic circuitry regulating aldosterone biosynthesis in the adrenal cortex Human Molecular Genetics. 21: 4922-4929. PMID 22918120 DOI: 10.1093/Hmg/Dds333 |
0.318 |
|
| 2012 |
Teufel A, Becker D, Weber SN, Dooley S, Breitkopf-Heinlein K, Maass T, Hochrath K, Krupp M, Marquardt JU, Kolb M, Korn B, Niehrs C, Zimmermann T, Godoy P, Galle PR, et al. Identification of RARRES1 as a core regulator in liver fibrosis. Journal of Molecular Medicine (Berlin, Germany). 90: 1439-47. PMID 22669512 DOI: 10.1007/S00109-012-0919-7 |
0.352 |
|
| 2012 |
Niehrs C, Acebron SP. Mitotic and mitogenic Wnt signalling. The Embo Journal. 31: 2705-13. PMID 22617425 DOI: 10.1038/Emboj.2012.124 |
0.404 |
|
| 2011 |
Glinka A, Dolde C, Kirsch N, Huang YL, Kazanskaya O, Ingelfinger D, Boutros M, Cruciat CM, Niehrs C. LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling Embo Reports. 12: 1055-1061. PMID 21909076 DOI: 10.1038/Embor.2011.175 |
0.37 |
|
| 2011 |
Kaufmann LT, Niehrs C. Gadd45a and Gadd45g regulate neural development and exit from pluripotency in Xenopus. Mechanisms of Development. 128: 401-11. PMID 21854844 DOI: 10.1016/J.Mod.2011.08.002 |
0.426 |
|
| 2011 |
Kaufmann LT, Gierl MS, Niehrs C. Gadd45a, Gadd45b and Gadd45g expression during mouse embryonic development. Gene Expression Patterns : Gep. 11: 465-70. PMID 21843656 DOI: 10.1016/J.Gep.2011.07.005 |
0.431 |
|
| 2011 |
Paulsen M, Legewie S, Eils R, Karaulanov E, Niehrs C. Negative feedback in the bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamic signaling range and canalizes development. Proceedings of the National Academy of Sciences of the United States of America. 108: 10202-7. PMID 21633009 DOI: 10.1073/Pnas.1100179108 |
0.404 |
|
| 2011 |
Liang J, Fu Y, Cruciat CM, Jia S, Wang Y, Tong Z, Tao Q, Ingelfinger D, Boutros M, Meng A, Niehrs C, Wu W. Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activation. Molecular and Cellular Biology. 31: 2577-90. PMID 21536646 DOI: 10.1128/Mcb.05103-11 |
0.406 |
|
| 2011 |
Ohkawara B, Glinka A, Niehrs C. Rspo3 binds syndecan 4 and induces Wnt/PCP signaling via clathrin-mediated endocytosis to promote morphogenesis. Developmental Cell. 20: 303-14. PMID 21397842 DOI: 10.1016/J.Devcel.2011.01.006 |
0.417 |
|
| 2011 |
Rousso SZ, Schyr RB, Gur M, Zouela N, Kot-Leibovich H, Shabtai Y, Koutsi-Urshanski N, Baldessari D, Pillemer G, Niehrs C, Fainsod A. Negative autoregulation of Oct3/4 through Cdx1 promotes the onset of gastrulation. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 796-807. PMID 21360791 DOI: 10.1002/Dvdy.22588 |
0.69 |
|
| 2011 |
Pietilä I, Ellwanger K, Railo A, Jokela T, Barrantes Idel B, Shan J, Niehrs C, Vainio SJ. Secreted Wnt antagonist Dickkopf-1 controls kidney papilla development coordinated by Wnt-7b signalling. Developmental Biology. 353: 50-60. PMID 21354128 DOI: 10.1016/J.Ydbio.2011.02.019 |
0.44 |
|
| 2011 |
Ribeiro D, Ellwanger K, Glagow D, Theofilopoulos S, Corsini NS, Martin-Villalba A, Niehrs C, Arenas E. Dkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesis. Plos One. 6: e15786. PMID 21347250 DOI: 10.1371/Journal.Pone.0015786 |
0.552 |
|
| 2011 |
Sytnikova YA, Kubarenko AV, Schäfer A, Weber AN, Niehrs C. Gadd45a is an RNA binding protein and is localized in nuclear speckles. Plos One. 6: e14500. PMID 21249130 DOI: 10.1371/Journal.Pone.0014500 |
0.318 |
|
| 2011 |
Ohkawara B, Niehrs C. An ATF2-based luciferase reporter to monitor non-canonical Wnt signaling in Xenopus embryos. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 188-94. PMID 21128306 DOI: 10.1002/Dvdy.22500 |
0.408 |
|
| 2010 |
Niehrs C, Acebron SP. Wnt signaling: multivesicular bodies hold GSK3 captive. Cell. 143: 1044-6. PMID 21183070 DOI: 10.1016/J.Cell.2010.12.003 |
0.358 |
|
| 2010 |
Niehrs C, Boutros M. Trafficking, acidification, and growth factor signaling Science Signaling. 3. PMID 20699474 DOI: 10.1126/Scisignal.3134Pe26 |
0.376 |
|
| 2010 |
Davidson G, Niehrs C. Emerging links between CDK cell cycle regulators and Wnt signaling. Trends in Cell Biology. 20: 453-60. PMID 20627573 DOI: 10.1016/J.Tcb.2010.05.002 |
0.406 |
|
| 2010 |
Buechling T, Bartscherer K, Ohkawara B, Chaudhary V, Spirohn K, Niehrs C, Boutros M. Wnt/frizzled signaling requires dprr, the drosophila homolog of the prorenin receptor Current Biology. 20: 1263-1268. PMID 20579883 DOI: 10.1016/J.Cub.2010.05.028 |
0.414 |
|
| 2010 |
Schulze J, Seitz S, Saito H, Schneebauer M, Marshall RP, Baranowsky A, Busse B, Schilling AF, Friedrich FW, Albers J, Spiro AS, Zustin J, Streichert T, Ellwanger K, Niehrs C, et al. Negative regulation of bone formation by the transmembrane Wnt antagonist Kremen-2. Plos One. 5: e10309. PMID 20436912 DOI: 10.1371/Journal.Pone.0010309 |
0.308 |
|
| 2010 |
Niehrs C, Shen J. Regulation of Lrp6 phosphorylation. Cellular and Molecular Life Sciences : Cmls. 67: 2551-62. PMID 20229235 DOI: 10.1007/S00018-010-0329-3 |
0.357 |
|
| 2010 |
Niehrs C. On growth and form: a Cartesian coordinate system of Wnt and BMP signaling specifies bilaterian body axes. Development (Cambridge, England). 137: 845-57. PMID 20179091 DOI: 10.1242/Dev.039651 |
0.356 |
|
| 2010 |
Wang Y, Fu Y, Gao L, Zhu G, Liang J, Gao C, Huang B, Fenger U, Niehrs C, Chen YG, Wu W. Xenopus skip modulates Wnt/beta-catenin signaling and functions in neural crest induction. The Journal of Biological Chemistry. 285: 10890-901. PMID 20103590 DOI: 10.1074/Jbc.M109.058347 |
0.413 |
|
| 2010 |
Cruciat CM, Ohkawara B, Acebron SP, Karaulanov E, Reinhard C, Ingelfinger D, Boutros M, Niehrs C. Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling Science. 327: 459-463. PMID 20093472 DOI: 10.1126/Science.1179802 |
0.384 |
|
| 2010 |
Niehrs C. O7. Regulation of Wnt/Lrp6 signalling Differentiation. 80. DOI: 10.1016/J.Diff.2010.09.150 |
0.413 |
|
| 2010 |
Ohkawara B, Niehrs C. P23. The role of Rspo3 in head cartilage morphogenesis Differentiation. 80. DOI: 10.1016/J.Diff.2010.09.029 |
0.318 |
|
| 2009 |
Davidson G, Shen J, Huang YL, Su Y, Karaulanov E, Bartscherer K, Hassler C, Stannek P, Boutros M, Niehrs C. Cell cycle control of wnt receptor activation. Developmental Cell. 17: 788-99. PMID 20059949 DOI: 10.1016/J.Devcel.2009.11.006 |
0.377 |
|
| 2009 |
Karaulanov E, Böttcher RT, Stannek P, Wu W, Rau M, Ogata S, Cho KW, Niehrs C. Unc5B interacts with FLRT3 and Rnd1 to modulate cell adhesion in Xenopus embryos. Plos One. 4: e5742. PMID 19492039 DOI: 10.1371/Journal.Pone.0005742 |
0.397 |
|
| 2009 |
Niehrs C. S12-04 Cell cycle regulation of a Wnt receptor Mechanisms of Development. 126: S12-S13. DOI: 10.1016/J.Mod.2009.06.975 |
0.308 |
|
| 2009 |
Rousso SZ, Schyr RBH, Gur M, Koutsi-Urshanski N, Baldessari D, Niehrs C, Fainsod A. 17-P011 Oct3/4 activates Cdx1 to terminate pluripotency at the onset of gastrulation Mechanisms of Development. 126: S274. DOI: 10.1016/J.Mod.2009.06.732 |
0.617 |
|
| 2008 |
Kazanskaya O, Ohkawara B, Heroult M, Wu W, Maltry N, Augustin HG, Niehrs C. The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development. Development (Cambridge, England). 135: 3655-64. PMID 18842812 DOI: 10.1242/Dev.027284 |
0.383 |
|
| 2008 |
Ellwanger K, Saito H, Clément-Lacroix P, Maltry N, Niedermeyer J, Lee WK, Baron R, Rawadi G, Westphal H, Niehrs C. Targeted disruption of the Wnt regulator Kremen induces limb defects and high bone density. Molecular and Cellular Biology. 28: 4875-82. PMID 18505822 DOI: 10.1128/Mcb.00222-08 |
0.365 |
|
| 2007 |
Hassler C, Cruciat CM, Huang YL, Kuriyama S, Mayor R, Niehrs C. Kremen is required for neural crest induction in Xenopus and promotes LRP6-mediated Wnt signaling. Development (Cambridge, England). 134: 4255-63. PMID 17978005 DOI: 10.1242/Dev.005942 |
0.456 |
|
| 2007 |
Carmona-Fontaine C, Acuña G, Ellwanger K, Niehrs C, Mayor R. Neural crests are actively precluded from the anterior neural fold by a novel inhibitory mechanism dependent on Dickkopf1 secreted by the prechordal mesoderm. Developmental Biology. 309: 208-21. PMID 17669393 DOI: 10.1016/J.Ydbio.2007.07.006 |
0.367 |
|
| 2007 |
Ogata S, Morokuma J, Hayata T, Kolle G, Niehrs C, Ueno N, Cho KW. TGF-beta signaling-mediated morphogenesis: modulation of cell adhesion via cadherin endocytosis. Genes & Development. 21: 1817-31. PMID 17639085 DOI: 10.1101/Gad.1541807 |
0.388 |
|
| 2007 |
Bilic J, Huang YL, Davidson G, Zimmermann T, Cruciat CM, Bienz M, Niehrs C. Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation. Science (New York, N.Y.). 316: 1619-22. PMID 17569865 DOI: 10.1126/Science.1137065 |
0.388 |
|
| 2007 |
Pinho S, Niehrs C. Dkk3 is required for TGF-beta signaling during Xenopus mesoderm induction. Differentiation; Research in Biological Diversity. 75: 957-67. PMID 17490412 DOI: 10.1111/J.1432-0436.2007.00185.X |
0.445 |
|
| 2007 |
Caneparo L, Huang YL, Staudt N, Tada M, Ahrendt R, Kazanskaya O, Niehrs C, Houart C. Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/beta catenin and Wnt/PCP activities, through interaction with the Dally-like homolog Knypek. Genes & Development. 21: 465-80. PMID 17322405 DOI: 10.1101/Gad.406007 |
0.368 |
|
| 2007 |
Niehrs C. Function and biological roles of the Dickkopf family of Wnt modulators. Oncogene. 25: 7469-81. PMID 17143291 DOI: 10.1038/Sj.Onc.1210054 |
0.417 |
|
| 2006 |
Morvan F, Boulukos K, Clément-Lacroix P, Roman Roman S, Suc-Royer I, Vayssière B, Ammann P, Martin P, Pinho S, Pognonec P, Mollat P, Niehrs C, Baron R, Rawadi G. Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 21: 934-45. PMID 16753024 DOI: 10.1359/Jbmr.060311 |
0.306 |
|
| 2006 |
Cruciat CM, Hassler C, Niehrs C. The MRH protein Erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition. The Journal of Biological Chemistry. 281: 12986-93. PMID 16531414 DOI: 10.1074/Jbc.M511872200 |
0.381 |
|
| 2006 |
Guder C, Pinho S, Nacak TG, Schmidt HA, Hobmayer B, Niehrs C, Holstein TW. An ancient Wnt-Dickkopf antagonism in Hydra. Development (Cambridge, England). 133: 901-11. PMID 16452091 DOI: 10.1242/Dev.02265 |
0.472 |
|
| 2006 |
Karaulanov EE, Böttcher RT, Niehrs C. A role for fibronectin-leucine-rich transmembrane cell-surface proteins in homotypic cell adhesion. Embo Reports. 7: 283-90. PMID 16440004 DOI: 10.1038/Sj.Embor.7400614 |
0.393 |
|
| 2006 |
Cho KW, Ogata S, Morokuma J, Hayata T, Kolle G, Niehrs C, Ueno. A novel FLRT3 and Rnd1 pathway involved in TGF-β signaling-mediated cellular morphogenesis Developmental Biology. 295: 393. DOI: 10.1016/J.Ydbio.2006.04.204 |
0.347 |
|
| 2005 |
Davidson G, Wu W, Shen J, Bilic J, Fenger U, Stannek P, Glinka A, Niehrs C. Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction. Nature. 438: 867-72. PMID 16341016 DOI: 10.1038/Nature04170 |
0.429 |
|
| 2005 |
Niehrs C. Axis formation: redundancy rules. Current Biology : Cb. 15: R391-3. PMID 15916944 DOI: 10.1016/J.Cub.2005.05.002 |
0.331 |
|
| 2005 |
Baldessari D, Shin Y, Krebs O, König R, Koide T, Vinayagam A, Fenger U, Mochii M, Terasaka C, Kitayama A, Peiffer D, Ueno N, Eils R, Cho KW, Niehrs C. Global gene expression profiling and cluster analysis in Xenopus laevis. Mechanisms of Development. 122: 441-75. PMID 15763214 DOI: 10.1016/J.Mod.2004.11.007 |
0.396 |
|
| 2005 |
Pollet N, Muncke N, Verbeek B, Li Y, Fenger U, Delius H, Niehrs C. An atlas of differential gene expression during early Xenopus embryogenesis. Mechanisms of Development. 122: 365-439. PMID 15763213 DOI: 10.1016/J.Mod.2004.11.009 |
0.69 |
|
| 2005 |
Böttcher RT, Niehrs C. Fibroblast growth factor signaling during early vertebrate development. Endocrine Reviews. 26: 63-77. PMID 15689573 DOI: 10.1210/Er.2003-0040 |
0.4 |
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| 2005 |
Huttner W, Niehrs C, Vannier C. Bind or bleed. Current Biology : Cb. 1: 309-10. PMID 15336107 DOI: 10.1016/0960-9822(91)90094-D |
0.435 |
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| 2004 |
Kazanskaya O, Glinka A, del Barco Barrantes I, Stannek P, Niehrs C, Wu W. R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis. Developmental Cell. 7: 525-34. PMID 15469841 DOI: 10.1016/J.Devcel.2004.07.019 |
0.373 |
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| 2004 |
Hansis C, Barreto G, Maltry N, Niehrs C. Nuclear reprogramming of human somatic cells by xenopus egg extract requires BRG1. Current Biology : Cb. 14: 1475-80. PMID 15324664 DOI: 10.1016/J.Cub.2004.08.031 |
0.35 |
|
| 2004 |
Niehrs C. Regionally specific induction by the Spemann-Mangold organizer. Nature Reviews. Genetics. 5: 425-34. PMID 15153995 DOI: 10.1038/Nrg1347 |
0.378 |
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| 2004 |
Niehrs C. Norrin and frizzled; a new vein for the eye. Developmental Cell. 6: 453-4. PMID 15068782 DOI: 10.1016/S1534-5807(04)00102-9 |
0.31 |
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| 2004 |
König R, Baldessari D, Pollet N, Niehrs C, Eils R. Reliability of gene expression ratios for cDNA microarrays in multiconditional experiments with a reference design. Nucleic Acids Research. 32: e29. PMID 14966261 DOI: 10.1093/Nar/Gnh027 |
0.646 |
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| 2004 |
Karaulanov E, Knöchel W, Niehrs C. Transcriptional regulation of BMP4 synexpression in transgenic Xenopus. The Embo Journal. 23: 844-56. PMID 14963489 DOI: 10.1038/Sj.Emboj.7600101 |
0.406 |
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| 2004 |
Böttcher RT, Pollet N, Delius H, Niehrs C. The transmembrane protein XFLRT3 forms a complex with FGF receptors and promotes FGF signalling. Nature Cell Biology. 6: 38-44. PMID 14688794 DOI: 10.1038/Ncb1082 |
0.684 |
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| 2003 |
Pollet N, Delius H, Niehrs C. In situ analysis of gene expression in Xenopus embryos. Comptes Rendus Biologies. 326: 1011-7. PMID 14744108 DOI: 10.1016/J.Crvi.2003.09.019 |
0.691 |
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| 2003 |
del Barco Barrantes I, Davidson G, Gröne HJ, Westphal H, Niehrs C. Dkk1 and noggin cooperate in mammalian head induction. Genes & Development. 17: 2239-44. PMID 12952897 DOI: 10.1101/Gad.269103 |
0.347 |
|
| 2003 |
Niehrs C. Developmental biology: a tale of tails. Nature. 424: 375-6. PMID 12879046 DOI: 10.1038/424375A |
0.304 |
|
| 2003 |
Li Y, Fenger U, Niehrs C, Pollet N. Cyclic expression of esr9 gene in Xenopus presomitic mesoderm. Differentiation; Research in Biological Diversity. 71: 83-9. PMID 12558606 DOI: 10.1046/J.1432-0436.2003.700608.X |
0.685 |
|
| 2003 |
Mao B, Niehrs C. Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling. Gene. 302: 179-83. PMID 12527209 DOI: 10.1016/S0378-1119(02)01106-X |
0.417 |
|
| 2002 |
Davidson G, Mao B, del Barco Barrantes I, Niehrs C. Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning. Development (Cambridge, England). 129: 5587-96. PMID 12421700 DOI: 10.1242/Dev.00154 |
0.432 |
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| 2002 |
Mao B, Wu W, Davidson G, Marhold J, Li M, Mechler BM, Delius H, Hoppe D, Stannek P, Walter C, Glinka A, Niehrs C. Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling. Nature. 417: 664-7. PMID 12050670 DOI: 10.1038/Nature756 |
0.407 |
|
| 2002 |
Niehrs C, Meinhardt H. Developmental biology: Modular feedback Nature. 417: 35-36. PMID 11986655 DOI: 10.1038/417035A |
0.367 |
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| 2001 |
Mukhopadhyay M, Shtrom S, Rodriguez-Esteban C, Chen L, Tsukui T, Gomer L, Dorward DW, Glinka A, Grinberg A, Huang SP, Niehrs C, Izpisúa Belmonte JC, Westphal H. Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse. Developmental Cell. 1: 423-34. PMID 11702953 DOI: 10.1016/S1534-5807(01)00041-7 |
0.391 |
|
| 2001 |
Niehrs C. Developmental biology. Solving a sticky problem. Nature. 413: 787-8. PMID 11677588 DOI: 10.1038/35101682 |
0.325 |
|
| 2001 |
Duncan PI, Pollet N, Niehrs C, Nigg EA. Cloning and characterization of Plx2 and Plx3, two additional Polo-like kinases from Xenopus laevis. Experimental Cell Research. 270: 78-87. PMID 11597129 DOI: 10.1006/Excr.2001.5333 |
0.665 |
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| 2001 |
Lamar E, Deblandre G, Wettstein D, Gawantka V, Pollet N, Niehrs C, Kintner C. Nrarp is a novel intracellular component of the Notch signaling pathway. Genes & Development. 15: 1885-99. PMID 11485984 DOI: 10.1101/Gad.908101 |
0.717 |
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| 2001 |
Pollet N, Niehrs C. Expression profiling by systematic high-throughput in situ hybridization to whole-mount embryos. Methods in Molecular Biology (Clifton, N.J.). 175: 309-21. PMID 11462844 DOI: 10.1385/1-59259-235-X:309 |
0.645 |
|
| 2001 |
Mao B, Wu W, Li Y, Hoppe D, Stannek P, Glinka A, Niehrs C. LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature. 411: 321-5. PMID 11357136 DOI: 10.1038/35077108 |
0.402 |
|
| 2001 |
Chen Y, Pollet N, Niehrs C, Pieler T. Increased XRALDH2 activity has a posteriorizing effect on the central nervous system of Xenopus embryos. Mechanisms of Development. 101: 91-103. PMID 11231062 DOI: 10.1016/S0925-4773(00)00558-X |
0.633 |
|
| 2001 |
Kiecker C, Niehrs C. The role of prechordal mesendoderm in neural patterning. Current Opinion in Neurobiology. 11: 27-33. PMID 11179869 DOI: 10.1016/S0959-4388(00)00170-7 |
0.724 |
|
| 2001 |
Wu W, Glinka A, Delius H, Niehrs C. Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling. Current Biology : Cb. 10: 1611-4. PMID 11137016 DOI: 10.1016/S0960-9822(00)00868-X |
0.412 |
|
| 2001 |
Niehrs C, Kazanskaya O, Wu W, Glinka A. Dickkopf1 and the Spemann-Mangold head organizer. The International Journal of Developmental Biology. 45: 237-240. DOI: 10.1387/Ijdb.11291852 |
0.36 |
|
| 2000 |
de Souza FS, Niehrs C. Anterior endoderm and head induction in early vertebrate embryos. Cell and Tissue Research. 300: 207-17. PMID 10867817 DOI: 10.1007/S004410000204 |
0.337 |
|
| 2000 |
Otto C, Schütz G, Niehrs C, Glinka A. Dissecting GHRH- and pituitary adenylate cyclase activating polypeptide-mediated signalling in Xenopus Mechanisms of Development. 94: 111-116. PMID 10842063 DOI: 10.1016/S0925-4773(00)00302-6 |
0.309 |
|
| 2000 |
Kiecker C, Müller F, Wu W, Glinka A, Strähle U, Niehrs C. Phenotypic effects in Xenopus and zebrafish suggest that one-eyed pinhead functions as antagonist of BMP signalling. Mechanisms of Development. 94: 37-46. PMID 10842057 DOI: 10.1016/S0925-4773(00)00329-4 |
0.753 |
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| 2000 |
Dosch R, Niehrs C. Requirement for anti-dorsalizing morphogenetic protein in organizer patterning. Mechanisms of Development. 90: 195-203. PMID 10640703 DOI: 10.1016/S0925-4773(99)00245-2 |
0.385 |
|
| 2000 |
Pollet N, Schmidt HA, Gawantka V, Vingron M, Niehrs C. Axeldb: a Xenopus laevis database focusing on gene expression. Nucleic Acids Research. 28: 139-40. PMID 10592204 DOI: 10.1093/Nar/28.1.139 |
0.654 |
|
| 2000 |
Monaghan AP, Kioschis P, Wu W, Zuniga A, Bock D, Poustka A, Delius H, Niehrs C. Dickkopf genes are co-ordinately expressed in mesodermal lineages. Mechanisms of Development. 87: 45-56. PMID 10495270 DOI: 10.1016/S0925-4773(99)00138-0 |
0.442 |
|
| 1999 |
Niehrs C, Pollet N. Synexpression groups in eukaryotes. Nature. 402: 483-7. PMID 10591207 DOI: 10.1038/990025 |
0.662 |
|
| 1999 |
de Souza FS, Gawantka V, Gómez AP, Delius H, Ang SL, Niehrs C. The zinc finger gene Xblimp1 controls anterior endomesodermal cell fate in Spemann's organizer. The Embo Journal. 18: 6062-72. PMID 10545117 DOI: 10.1093/Emboj/18.21.6062 |
0.372 |
|
| 1999 |
Lutz B, Schmid W, Niehrs C, Schütz G. Essential role of CREB family proteins during Xenopus embryogenesis. Mechanisms of Development. 88: 55-66. PMID 10525188 DOI: 10.1016/S0925-4773(99)00170-7 |
0.411 |
|
| 1999 |
Onichtchouk D, Chen YG, Dosch R, Gawantka V, Delius H, Massagué J, Niehrs C. Silencing of TGF-beta signalling by the pseudoreceptor BAMBI. Nature. 401: 480-485. PMID 10519551 DOI: 10.1038/46794 |
0.364 |
|
| 1999 |
Askjaer P, Bachi A, Wilm M, Bischoff FR, Weeks DL, Ogniewski V, Ohno M, Niehrs C, Kjems J, Mattaj IW, Fornerod M. RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase. Molecular and Cellular Biology. 19: 6276-85. PMID 10454574 DOI: 10.1128/Mcb.19.9.6276 |
0.561 |
|
| 1999 |
Niehrs C. Head in the WNT: the molecular nature of Spemann's head organizer. Trends in Genetics : Tig. 15: 314-9. PMID 10431193 DOI: 10.1016/S0168-9525(99)01767-9 |
0.345 |
|
| 1999 |
Jen WC, Gawantka V, Pollet N, Niehrs C, Kintner C. Periodic repression of Notch pathway genes governs the segmentation of Xenopus embryos. Genes & Development. 13: 1486-99. PMID 10364164 DOI: 10.1101/Gad.13.11.1486 |
0.716 |
|
| 1998 |
Gawantka V, Pollet N, Delius H, Vingron M, Pfister R, Nitsch R, Blumenstock C, Niehrs C. Gene expression screening in Xenopus identifies molecular pathways, predicts gene function and provides a global view of embryonic patterning. Mechanisms of Development. 77: 95-141. PMID 9831640 DOI: 10.1016/S0925-4773(98)00115-4 |
0.687 |
|
| 1998 |
Beisswanger R, Corbeil D, Vannier C, Thiele C, Dohrmann U, Kellner R, Ashman K, Niehrs C, Huttner WB. Existence of distinct tyrosylprotein sulfotransferase genes: molecular characterization of tyrosylprotein sulfotransferase-2. Proceedings of the National Academy of Sciences of the United States of America. 95: 11134-9. PMID 9736702 DOI: 10.1073/Pnas.95.19.11134 |
0.51 |
|
| 1998 |
Glinka A, Wu W, Delius H, Monaghan AP, Blumenstock C, Niehrs C. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature. 391: 357-62. PMID 9450748 DOI: 10.1038/34848 |
0.356 |
|
| 1997 |
Glinka A, Wu W, Onichtchouk D, Blumenstock C, Niehrs C. Head induction by simultaneous repression of Bmp and Wnt signalling in Xenopus. Nature. 389: 517-9. PMID 9333244 DOI: 10.1038/39092 |
0.398 |
|
| 1997 |
Meersseman G, Verschueren K, Nelles L, Blumenstock C, Kraft H, Wuytens G, Remacle J, Kozak CA, Tylzanowski P, Niehrs C, Huylebroeck D. The C-terminal domain of Mad-like signal transducers is sufficient for biological activity in the Xenopus embryo and transcriptional activation. Mechanisms of Development. 61: 127-40. PMID 9076683 DOI: 10.1016/S0925-4773(96)00629-6 |
0.33 |
|
| 1997 |
Glinka A, Delius H, Blumenstock C, Niehrs C. Combinatorial signalling by Xwnt-11 and Xnr3 in the organizer epithelium. Mechanisms of Development. 60: 221-31. PMID 9025074 DOI: 10.1016/S0925-4773(96)00624-7 |
0.431 |
|
| 1995 |
Gawantka V, Delius H, Hirschfeld K, Blumenstock C, Niehrs C. Antagonizing the Spemann organizer: role of the homeobox gene Xvent-1. The Embo Journal. 14: 6268-6279. DOI: 10.1002/J.1460-2075.1995.Tb00317.X |
0.443 |
|
| 1995 |
Steinbeisser H, Fainsod A, Niehrs C, Sasai Y, De Robertis EM. The role of gsc and BMP-4 in dorsal-ventral patterning of the marginal zone in Xenopus: a loss-of-function study using antisense RNA. The Embo Journal. 14: 5230-5243. DOI: 10.1002/j.1460-2075.1995.tb00208.x |
0.716 |
|
| 1994 |
Niehrs C, Beißwanger R, Huttner WB. Protein tyrosine sulfation, 1993 - an update Chemico-Biological Interactions. 92: 257-271. PMID 8033259 DOI: 10.1016/0009-2797(94)90068-X |
0.484 |
|
| 1994 |
Niehrs C, Steinbeisser H, De Robertis EM. Mesodermal patterning by a gradient of the vertebrate homeobox gene goosecoid. Science (New York, N.Y.). 263: 817-20. PMID 7905664 DOI: 10.1126/SCIENCE.7905664 |
0.526 |
|
| 1993 |
Niehrs C, Keller R, Cho KW, De Robertis EM. The homeobox gene goosecoid controls cell migration in Xenopus embryos. Cell. 72: 491-503. PMID 8095000 DOI: 10.1016/0092-8674(93)90069-3 |
0.541 |
|
| 1992 |
Niehrs C, De Robertis EM. Vertebrate axis formation. Current Opinion in Genetics & Development. 2: 550-5. PMID 1356042 DOI: 10.1016/S0959-437X(05)80170-4 |
0.576 |
|
| 1990 |
Niehrs C, Huttner W. Purification and characterization of tyrosylprotein sulfotransferase. The Embo Journal. 9: 35-42. DOI: 10.1002/J.1460-2075.1990.Tb08077.X |
0.461 |
|
| 1989 |
Rosa P, Weiss U, Pepperkok R, Ansorge W, Niehrs C, Stelzer EH, Huttner WB. An antibody against secretogranin I (chromogranin B) is packaged into secretory granules. The Journal of Cell Biology. 109: 17-34. PMID 2663878 DOI: 10.1083/JCB.109.1.17 |
0.455 |
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