☰

Robert Charles Hider, PhD - Publications

Affiliations: 
1967 Department of Biochemistry King's College London, London, UK 
 1968- Department of Physiology and Biochemistry University of Reading, Earley, England, United Kingdom 
 1980-1993 Department of Chemistry Essex University 
 1993- Institute of Pharmaceutical Science, Faculty of Life Science & Medicine King's College London, London, UK 
Area:
Iron Chelator, Chelator, Medicinal Chemistry, Chemical Biology, Amino Acid, Biosynthesis
Tree Info Similar researchers PubMed Report error

334 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hider RC, Pourzand C, Ma Y, Cilibrizzi A. Optical Imaging Opportunities to Inspect the Nature of Cytosolic Iron Pools. Molecules (Basel, Switzerland). 28. PMID 37764245 DOI: 10.3390/molecules28186467  0.824
2023 Ran Y, Moursy M, Hider RC, Cilibrizzi A. The Colorimetric Detection of the Hydroxyl Radical. International Journal of Molecular Sciences. 24. PMID 36835574 DOI: 10.3390/ijms24044162  0.697
2022 Garbowski MW, Cabantchik I, Hershko C, Hider R, Porter JB. The clinical relevance of detectable plasma iron species in iron overload states and subsequent to intravenous iron-carbohydrate administration. American Journal of Hematology. PMID 36565452 DOI: 10.1002/ajh.26819  0.335
2022 Floresta G, Memdouh S, Pham T, Ma MT, Blower PJ, Hider RC, Abbate V, Cilibrizzi A. Targeting integrin αvβ6 with gallium-68 tris (hydroxypyridinone) based PET probes. Dalton Transactions (Cambridge, England : 2003). PMID 35972045 DOI: 10.1039/d2dt00980c  0.78
2022 Cilibrizzi A, Wang JT, Memdouh S, Iacovone A, McElroy K, Jaffar N, Young JD, Hider RC, Blower P, Al-Jamal K, Abbate V. PSMA-targeted NIR probes for image-guided detection of prostate cancer. Colloids and Surfaces. B, Biointerfaces. 218: 112734. PMID 35952398 DOI: 10.1016/j.colsurfb.2022.112734  0.766
2022 Cilibrizzi A, Pourzand C, Abbate V, Reelfs O, Versari L, Floresta G, Hider R. The synthesis and properties of mitochondrial targeted iron chelators. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. PMID 35366134 DOI: 10.1007/s10534-022-00383-8  0.778
2022 Zhu YZ, Chen K, Chen YL, Zhang C, Xie YY, Hider RC, Zhou T. Design and synthesis of novel stilbene-hydroxypyridinone hybrids as tyrosinase inhibitors and their application in the anti-browning of freshly-cut apples. Food Chemistry. 385: 132730. PMID 35318180 DOI: 10.1016/j.foodchem.2022.132730  0.741
2022 Khoja KK, Howes MR, Hider R, Sharp PA, Farrell IW, Latunde-Dada GO. Cytotoxicity of Fenugreek Sprout and Seed Extracts and Their Bioactive Constituents on MCF-7 Breast Cancer Cells. Nutrients. 14. PMID 35215434 DOI: 10.3390/nu14040784  0.586
2021 Xia W, Chen K, Zhu YZ, Zhang CJ, Chen YL, Wang F, Xie YY, Hider RC, Zhou T. Antioxidant and anti-tyrosinase activity of a novel stilbene analogue as an anti-browning agent. Journal of the Science of Food and Agriculture. PMID 34923627 DOI: 10.1002/jsfa.11731  0.713
2021 Garbowski MW, Porter JB, Hider R. Response to Cabantchik & Hershko Commentary "Plasma nontransferrin bound iron - nontransferrin bound iron revisited: Implications for systemic iron overload and in iv iron supplementation". American Journal of Hematology. PMID 34817863 DOI: 10.1002/ajh.26419  0.343
2021 Young JD, Ma MT, Eykyn TR, Andrew Atkinson R, Abbate V, Cilibrizzi A, Hider RC, Blower PJ. Corrigendum to "Dipeptide inhibitors of the prostate specific membrane antigen (PSMA): A comparison of urea and thiourea derivatives" [Bioorganic Med. Chem. Lett. 42 (2021) 128044]. Bioorganic & Medicinal Chemistry Letters. 48: 128231. PMID 34229996 DOI: 10.1016/j.bmcl.2021.128231  0.683
2021 Young JD, Ma MT, Eykyn TR, Atkinson RA, Abbate V, Cilibrizzi A, Hider RC, Blower PJ. Dipeptide Inhibitors of the Prostate Specific Membrane Antigen (PSMA): A Comparison of Urea and Thiourea Derivatives. Bioorganic & Medicinal Chemistry Letters. 128044. PMID 33865971 DOI: 10.1016/j.bmcl.2021.128044  0.72
2021 Hider R, Aviles MV, Chen YL, Latunde-Dada GO. The Role of GSH in Intracellular Iron Trafficking. International Journal of Molecular Sciences. 22. PMID 33525417 DOI: 10.3390/ijms22031278  0.827
2020 O'Keeffe R, Latunde-Dada GO, Chen YL, Kong XL, Cilibrizzi A, Hider RC. Glutathione and the intracellular labile heme pool. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. PMID 33301081 DOI: 10.1007/s10534-020-00274-w  0.832
2020 Sun Y, Pham AN, Hider RC, Zheng H, Waite TD. Effectiveness of the Iron Chelator CN128 in Mitigating the Formation of Dopamine Oxidation Products Associated with the Progression of Parkinson's Disease. Acs Chemical Neuroscience. 11: 3646-3657. PMID 33143428 DOI: 10.1021/acschemneuro.0c00557  0.324
2020 Garbowski MW, Bansal S, Porter JB, Mori C, Burckhardt S, Hider RC. Intravenous iron preparations transiently generate non-transferrin-bound iron from two proposed pathways. Haematologica. PMID 33054113 DOI: 10.3324/Haematol.2020.250803  0.784
2020 Gacesa R, Tripodi AAP, Cilibrizzi A, Leggio A, Hider R, Abbate V. Solid-Phase Synthesis and Analysis of Iron-Binding Catecholato Chelators. International Journal of Molecular Sciences. 21. PMID 33053658 DOI: 10.3390/ijms21207498  0.793
2020 Tewari D, Lloyd-Jones K, Hider RC, Collins H. HPO iron chelator, CP655, causes the G1/S phase cell cycle block via p21 upregulation. Immunity, Inflammation and Disease. PMID 32865890 DOI: 10.1002/Iid3.342  0.412
2020 Singh LR, Chen YL, Xie YY, Xia W, Gong XW, Hider RC, Zhou T. Functionality study of chalcone-hydroxypyridinone hybrids as tyrosinase inhibitors and influence on anti-tyrosinase activity. Journal of Enzyme Inhibition and Medicinal Chemistry. 35: 1562-1567. PMID 32746652 DOI: 10.1080/14756366.2020.1801669  0.741
2020 Chuljerm H, Deeudom M, Fucharoen S, Mazzacuva F, Hider RC, Srichairatanakool S, Cilibrizzi A. Characterization of two siderophores produced by Bacillus megaterium: A preliminary investigation into their potential as therapeutic agents. Biochimica Et Biophysica Acta. General Subjects. 1864: 129670. PMID 32565293 DOI: 10.1016/J.Bbagen.2020.129670  0.713
2020 Chen W, Yuan X, Li Z, Lu Z, Kong S, Jiang H, Du H, Pan X, Nandi M, Kong X, Brown K, Liu Z, Zhang G, Hider RC, Yu Y. CN128, a new orally active hydroxypyridinone iron chelator. Journal of Medicinal Chemistry. PMID 32208614 DOI: 10.1021/Acs.Jmedchem.0C00137  0.813
2020 Poeschl A, Mountford DM, Hider RC, Cilibrizzi A. Synthetic Approaches for Piperidone-Based Templates as Scaffolds to Access Chirally Enriched Donepezil Analogues. Acs Omega. 5: 2378-2396. PMID 32064399 DOI: 10.1021/acsomega.9b03808  0.783
2020 Ding Y, Ma R, Hider RC, Ma Y. Acid‐Catalyzed Pseudo Five‐Component Annulation for a General One‐Pot Synthesis of 2,4,6‐Triaryl Pyrimidines Asian Journal of Organic Chemistry. 9: 242-246. DOI: 10.1002/Ajoc.201900700  0.733
2019 Gao Y, Hider RC, Ma Y. An efficient 3-acylquinoline synthesis from acetophenones and anthranil C(sp)-H bond activation mediated by Selectfluor. Rsc Advances. 9: 10340-10344. PMID 35520934 DOI: 10.1039/c9ra01481k  0.723
2019 Chuljerm H, Chen YL, Srichairatanakool S, Hider RC, Cilibrizzi A. Synthesis and iron coordination properties of schizokinen and its imide derivative. Dalton Transactions (Cambridge, England : 2003). PMID 31742278 DOI: 10.1039/C9Dt02731A  0.836
2019 Crichton RR, Ward RJ, Hider RC. The Efficacy of Iron Chelators for Removing Iron from Specific Brain Regions and the Pituitary-Ironing out the Brain. Pharmaceuticals (Basel, Switzerland). 12. PMID 31533229 DOI: 10.3390/Ph12030138  0.442
2019 Yan H, Xiao XQ, Hider RC, Ma Y. A Simple Metal-Free Cyclization for the Synthesis of 4-Methylene-3-Substituted Quinazolinone and Quinazolinthione Derivatives: Experiment and Theory. Frontiers in Chemistry. 7: 584. PMID 31475141 DOI: 10.3389/Fchem.2019.00584  0.742
2019 Shao LL, Zhou JM, Zhu Q, Wang XL, Hider RC, Zhou T. Enzymatic characteristics of polyphenoloxidase from shrimp () and its inhibition by a novel hydroxypyridinone derivative. Food Science and Biotechnology. 28: 1047-1055. PMID 31275704 DOI: 10.1007/S10068-018-00544-X  0.772
2019 Harper RA, Petersen L, Saleh M, Proctor GB, Carpenter GH, Gambogi R, Hider R, Jones SA. Targeting macrophages and their recruitment in the oral cavity using swellable (+) alpha tocopheryl phosphate nanostructures. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 31195135 DOI: 10.1016/J.Nano.2019.04.013  0.688
2019 Faruqu FN, Wang JT, Xu L, McNickle L, Chong EM, Walters A, Gurney M, Clayton A, Smyth LA, Hider R, Sosabowski J, Al-Jamal KT. Membrane Radiolabelling of Exosomes for Comparative Biodistribution Analysis in Immunocompetent and Immunodeficient Mice - A Novel and Universal Approach. Theranostics. 9: 1666-1682. PMID 31037130 DOI: 10.7150/Thno.27891  0.676
2019 Imberti C, Chen YL, Foley CA, Ma MT, Paterson BM, Wang Y, Young JD, Hider RC, Blower PJ. Tuning the properties of tris(hydroxypyridinone) ligands: efficient Ga chelators for PET imaging. Dalton Transactions (Cambridge, England : 2003). PMID 30860215 DOI: 10.1039/C8Dt04454F  0.745
2019 Hider RC, Hoffbrand AV. The Role of Deferiprone in Iron Chelation. Reply. The New England Journal of Medicine. 380: 892-893. PMID 30811927 DOI: 10.1056/NEJMc1817335#sa3  0.345
2019 Zhou T, Kong XL, Hider RC. Synthesis and iron chelating properties of hydroxypyridinone and hydroxypyranone hexadentate ligands. Dalton Transactions (Cambridge, England : 2003). PMID 30793715 DOI: 10.1039/C8Dt05014G  0.778
2019 Reelfs O, Abbate V, Cilibrizzi A, Pook MA, Hider RC, Pourzand C. The role of mitochondrial labile iron in Friedreich's ataxia skin fibroblasts sensitivity to ultraviolet A. Metallomics : Integrated Biometal Science. PMID 30778428 DOI: 10.1039/C8Mt00257F  0.754
2019 Koppenol WH, Hider RC. Iron and redox cycling. Do's and don'ts. Free Radical Biology and Medicine. 133: 3-10. PMID 30236787 DOI: 10.1016/J.Freeradbiomed.2018.09.022  0.471
2019 Garbowski MW, Bansal SS, Porter JB, Burckhardt S, Hider R. NTBI Is Transiently Generated from Two Compartments during a Single Dose of Intravenous Iron - a Randomized Controlled Clinical Study Blood. 134: 2234-2234. DOI: 10.1182/Blood-2019-125618  0.772
2019 Yan H, Hider RC, Ma Y. Synthesis, characterisation and quantum chemical studies of a new series of iron chelatable fluorescent sensors Molecular Physics. 117: 661-671. DOI: 10.1080/00268976.2018.1533147  0.79
2019 Gao Y, Hider RC, Ma Y. An efficient 3-acylquinoline synthesis from acetophenones and anthranil via C(sp3)–H bond activation mediated by Selectfluor Rsc Advances. 9: 10340-10344. DOI: 10.1039/C9Ra01481K  0.737
2019 Yan M, Hider RC, Ma Y. Cu(II)- or Co(II)-Catalyzed C(SP3)–H oxidation of N,N-dimethylaminoethanol: facile synthesis of methylene-bridged biindoles and 3-formylindoles selectively Organic Chemistry Frontiers. 6: 1168-1172. DOI: 10.1039/C9Qo00097F  0.737
2019 Chen K, Shao L, Huo Y, Zhou J, Zhu Q, Hider RC, Zhou T. Antimicrobial and antioxidant effects of a hydroxypyridinone derivative containing an oxime ether moiety and its application in shrimp preservation Food Control. 95: 157-164. DOI: 10.1016/J.Foodcont.2018.08.008  0.781
2018 Hider RC, Hoffbrand AV. The Role of Deferiprone in Iron Chelation. The New England Journal of Medicine. 379: 2140-2150. PMID 30485781 DOI: 10.1056/Nejmra1800219  0.455
2018 Harper RA, Carpenter GH, Proctor GB, Harvey RD, Gambogi RJ, Geonnotti AR, Hider R, Jones SA. Diminishing biofilm resistance to antimicrobial nanomaterials through electrolyte screening of electrostatic interactions. Colloids and Surfaces. B, Biointerfaces. 173: 392-399. PMID 30317126 DOI: 10.1016/J.Colsurfb.2018.09.018  0.69
2018 Zhou T, Battah S, Mazzacuva F, Hider RC, Dobbin PS, MacRobert AJ. Design of Bifunctional Dendritic 5-Aminolevulinic Acid and Hydroxypyridinone Conjugates for Photodynamic Therapy. Bioconjugate Chemistry. PMID 30249090 DOI: 10.1021/Acs.Bioconjchem.8B00574  0.442
2018 Mei KC, Ghazaryan A, Teoh EZ, Summers HD, Li Y, Ballesteros B, Piasecka J, Walters A, Hider RC, Mailänder V, Al-Jamal KT. Protein-Corona-by-Design in 2D: A Reliable Platform to Decode Bio-Nano Interactions for the Next-Generation Quality-by-Design Nanomedicines. Advanced Materials (Deerfield Beach, Fla.). e1802732. PMID 30144166 DOI: 10.1002/Adma.201802732  0.772
2018 Cilibrizzi A, Abbate V, Chen YL, Ma Y, Zhou T, Hider RC. Hydroxypyridinone Journey into Metal Chelation. Chemical Reviews. PMID 30033720 DOI: 10.1021/Acs.Chemrev.8B00254  0.777
2018 Zhou T, Chen K, Kong LM, Liu MS, Ma YM, Xie YY, Hider RC. Synthesis, iron binding and antimicrobial properties of hexadentate 3-hydroxypyridinones-terminated dendrimers. Bioorganic & Medicinal Chemistry Letters. PMID 29886020 DOI: 10.1016/J.Bmcl.2018.05.058  0.83
2018 Harper RA, Saleh MM, Carpenter G, Abbate V, Proctor G, Harvey RD, Gambogi RJ, Geonnotti A, Hider R, Jones SA. Soft, adhesive (+) alpha tocopherol phosphate planar bilayers that control oral biofilm growth through a substantive antimicrobial effect. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 29410321 DOI: 10.1016/J.Nano.2017.12.024  0.746
2018 Fisher R, Lincoln L, Jackson MJ, Abbate V, Jenner P, Hider R, Lees A, Rose S. The effect of Banisteriopsis caapi (B. caapi) on the motor deficits in the MPTP-treated common marmoset model of Parkinson's disease. Phytotherapy Research : Ptr. PMID 29368409 DOI: 10.1002/Ptr.6017  0.594
2018 Benaouda F, Jones SA, Chana J, Dal Corno BM, Barlow DJ, Hider RC, Page CP, Forbes B. Ion-pairing with spermine targets theophylline to the lungs via the polyamine transport system. Molecular Pharmaceutics. PMID 29307184 DOI: 10.1021/Acs.Molpharmaceut.7B00715  0.622
2018 Shao LL, Wang XL, Chen K, Dong XW, Kong LM, Zhao DY, Hider RC, Zhou T. Novel hydroxypyridinone derivatives containing an oxime ether moiety: Synthesis, inhibition on mushroom tyrosinase and application in anti-browning of fresh-cut apples. Food Chemistry. 242: 174-181. PMID 29037675 DOI: 10.1016/J.Foodchem.2017.09.054  0.784
2018 Cheng MC, Chen Y, Cao MY, Ma Y, Hider RC. Synthesis and characterization of methyl substituted 3-hydroxypyridin-4-ones and their complexes with iron(III) Canadian Journal of Chemistry. 96: 293-298. DOI: 10.1139/Cjc-2017-0545  0.806
2018 Pelliccia S, Abbate V, Meneghetti F, Frascione N, Hider RC, Novellino E, Tron GC, Giustiniano M. On-water pyrrolidine-mediated domino synthesis of 2-iminoisatins Green Chemistry. 20: 3912-3915. DOI: 10.1039/C8Gc01090K  0.526
2017 Chen YL, Kong X, Xie Y, Hider RC. The interaction of pyridoxal isonicotinoyl hydrazone (PIH) and salicylaldehyde isonicotinoyl hydrazone (SIH) with iron. Journal of Inorganic Biochemistry. 180: 194-203. PMID 29329026 DOI: 10.1016/J.Jinorgbio.2017.12.007  0.802
2017 Abbate V, Hider R. Iron in biology. Metallomics : Integrated Biometal Science. 9: 1467-1469. PMID 29086787 DOI: 10.1039/C7Mt90039B  0.669
2017 Dubey RD, Klippstein R, Wang JT, Hodgins N, Mei KC, Sosabowski J, Hider RC, Abbate V, Gupta PN, Al-Jamal KT. Novel Hyaluronic Acid Conjugates for Dual Nuclear Imaging and Therapy in CD44-Expressing Tumors in Mice In Vivo. Nanotheranostics. 1: 59-79. PMID 29071179 DOI: 10.7150/ntno.17896  0.77
2017 Vlachodimitropoulou E, Chen YL, Garbowski M, Koonyosying P, Psaila B, Sola-Visner M, Cooper N, Hider R, Porter J. Eltrombopag: a powerful chelator of cellular or extracellular iron(III) alone or combined with a second chelator. Blood. PMID 28864815 DOI: 10.1182/Blood-2016-10-740241  0.799
2017 Shao LL, Xu J, Shi MJ, Wang XL, Li YT, Kong LM, Hider RC, Zhou T. Preparation, antioxidant and antimicrobial evaluation of hydroxamated degraded polysaccharides from Enteromorpha prolifera. Food Chemistry. 237: 481-487. PMID 28764023 DOI: 10.1016/J.Foodchem.2017.05.119  0.702
2017 Garbowski MW, Evans P, Vlachodimitropoulou E, Hider R, Porter JB. Residual erythropoiesis protects against myocardial hemosiderosis in transfusion-dependent thalassemia by lowering labile plasma iron via transient generation of apotransferrin. Haematologica. PMID 28642302 DOI: 10.3324/Haematol.2017.170605  0.454
2017 Young JD, Abbate V, Imberti C, Meszaros LK, Ma MT, Terry SY, Hider RC, Mullen GE, Blower PJ. (68)Ga-THP-PSMA: a PET imaging agent for prostate cancer offering rapid, room temperature, one-step kit-based radiolabeling. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 28408532 DOI: 10.2967/Jnumed.117.191882  0.539
2017 Battah S, Hider RC, MacRobert AJ, Dobbin PS, Zhou T. Hydroxypyridinone and 5-aminolaevulinic acid conjugates for photodynamic therapy. Journal of Medicinal Chemistry. PMID 28363026 DOI: 10.1021/Acs.Jmedchem.7B00346  0.442
2017 Cusnir R, Imberti C, Hider RC, Blower PJ, Ma MT. Hydroxypyridinone Chelators: From Iron Scavenging to Radiopharmaceuticals for PET Imaging with Gallium-68. International Journal of Molecular Sciences. 18. PMID 28075350 DOI: 10.3390/Ijms18010116  0.401
2017 Chen K, Zhao D, Chen Y, Wei X, Li Y, Kong L, Hider RC, Zhou T. A Novel Inhibitor Against Mushroom Tyrosinase with a Double Action Mode and Its Application in Controlling the Browning of Potato Food and Bioprocess Technology. 10: 2146-2155. DOI: 10.1007/S11947-017-1976-2  0.745
2016 Patel A, Keir SD, Brown MB, Hider R, Jones SA, Page CP. Using Salt Counterions to Modify β2-Agonist Behavior in Vivo. Molecular Pharmaceutics. PMID 27568865 DOI: 10.1021/Acs.Molpharmaceut.6B00448  0.558
2016 Chen BJ, Shi MJ, Cui S, Hao SX, Hider RC, Zhou T. Improved antioxidant and anti-tyrosinase activity of polysaccharide from Sargassum fusiforme by degradation. International Journal of Biological Macromolecules. PMID 27471085 DOI: 10.1016/J.Ijbiomac.2016.07.082  0.416
2016 Garbowski MW, Ma Y, Fucharoen S, Srichairatanakool S, Hider R, Porter JB. Clinical and methodological factors affecting nontransferrin-bound iron values using a novel fluorescent bead assay. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 27344508 DOI: 10.1016/J.Trsl.2016.05.005  0.805
2016 Zhao DY, Zhang MX, Dong XW, Hu YZ, Dai XY, Wei X, Hider RC, Zhang JC, Zhou T. Design and synthesis of novel hydroxypyridinone derivatives as potential tyrosinase inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27185329 DOI: 10.1016/J.Bmcl.2016.05.006  0.782
2016 Reelfs O, Abbate V, Hider RC, Pourzand C. A Powerful Mitochondria-Targeted Iron Chelator Affords High Photoprotection against Solar Ultraviolet A Radiation. The Journal of Investigative Dermatology. 136: 1692-700. PMID 27109868 DOI: 10.1016/J.Jid.2016.03.041  0.646
2016 Xie YY, Lu Z, Kong XL, Zhou T, Bansal S, Hider R. Systematic comparison of the mono-, dimethyl- and trimethyl 3-hydroxy-4(1H)-pyridones - Attempted optimization of the orally active iron chelator, deferiprone. European Journal of Medicinal Chemistry. 115: 132-140. PMID 27014847 DOI: 10.1016/J.Ejmech.2016.03.014  0.801
2016 Kulprachakarn K, Chen YL, Kong X, Arno MC, Hider RC, Srichairatanakool S, Bansal SS. Copper(II) binding properties of hepcidin. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 26883683 DOI: 10.1007/S00775-016-1342-2  0.785
2016 Reelfs O, Abbate V, Hider RC, Pourzand C. The Role Of Labile Iron In Solar Uva Radiation-Induced Mitochondrial Damage – Novel Mitochondrial Sensors And Iron Chelators For Photoprotection Journal of World Mitochondria Society. 2. DOI: 10.18143/Jwms_V2I2_2019  0.659
2016 Zhou T, Shao L, Battah S, Zhu C, Hider RC, Reeder BJ, Jabeen A, MacRobert AJ, Ren G, Liang X. Design and synthesis of 5-aminolaevulinic acid/3-hydroxypyridinone conjugates for photodynamic therapy: enhancement of protoporphyrin IX production and photo-toxicity in tumor cells Medchemcomm. 7: 1190-1196. DOI: 10.1039/C6Md00040A  0.708
2016 Li J, Olaleye ED, Kong X, Zhou T, Ma Y, Jurach J, Al Rugaie O, Hider RC, Zhang G, Alsam S, Abbate V. Macromolecular iron-chelators via RAFT-polymerization for the inhibition of methicillin-resistant Staphylococcus aureus growth Polymer (United Kingdom). 87: 64-72. DOI: 10.1016/J.Polymer.2016.01.073  0.825
2016 Dai XY, Zhang MX, Wei XY, Hider RC, Zhou T. Novel Multifunctional Hydroxypyridinone Derivatives as Potential Shrimp Preservatives Food and Bioprocess Technology. 1-10. DOI: 10.1007/S11947-016-1694-1  0.787
2016 Chen BJ, Zhou YJ, Wei XY, Xie HJ, Hider RC, Zhou T. Edible Antimicrobial Coating Incorporating a Polymeric Iron Chelator and Its Application in the Preservation of Surimi Product Food and Bioprocess Technology. 1-9. DOI: 10.1007/S11947-016-1693-2  0.725
2015 Li J, Lu Z, Kong X, Ma Y, Zhang X, Bansal SS, Abbate V, Hider RC. Design and synthesis of novel pegylated iron chelators with decreased metabolic rate. Future Medicinal Chemistry. 7: 2439-49. PMID 26670054 DOI: 10.4155/Fmc.15.154  0.808
2015 Saghaie L, Liu D, Hider RC. Synthesis of polymers containing 3-hydroxypyridin-4-one bidentate ligands for treatment of iron overload. Research in Pharmaceutical Sciences. 10: 364-377. PMID 26600863  0.346
2015 Abbate V, Reelfs O, Kong X, Pourzand C, Hider RC. Dual selective iron chelating probes with a potential to monitor mitochondrial labile iron pools. Chemical Communications (Cambridge, England). PMID 26567874 DOI: 10.1039/C5Cc06170A  0.667
2015 de Swart L, Hendriks JC, van der Vorm LN, Cabantchik ZI, Evans PJ, Hod EA, Brittenham GM, Furman Y, Wojczyk B, Janssen MC, Porter JB, Mattijssen VE, Biemond BJ, MacKenzie MA, Origa R, ... ... Hider RC, et al. Second International Round Robin for the Quantification of Serum Non-Transferrin-Bound Iron and Labile Plasma Iron in Patients with Iron-Overload Disorders. Haematologica. PMID 26385212 DOI: 10.3324/Haematol.2015.133983  0.463
2015 Mei KC, Rubio N, Costa PM, Kafa H, Abbate V, Festy F, Bansal SS, Hider RC, Al-Jamal KT. Synthesis of double-clickable functionalised graphene oxide for biological applications. Chemical Communications (Cambridge, England). 51: 14981-4. PMID 26295072 DOI: 10.1039/C5Cc05412E  0.775
2015 Bonaccorsi-Riani E, Danger R, Lozano JJ, Martinez-Picola M, Kodela E, Mas-Malavila R, Bruguera M, Collins HL, Hider RC, Martinez-Llordella M, Sanchez-Fueyo A. Iron Deficiency Impairs Intra-Hepatic Lymphocyte Mediated Immune Response. Plos One. 10: e0136106. PMID 26287688 DOI: 10.1371/Journal.Pone.0136106  0.403
2015 Rubio N, Mei KC, Klippstein R, Costa PM, Hodgins N, Wang JT, Festy F, Abbate V, Hider RC, Chan KL, Al-Jamal KT. Solvent-Free Click-Mechanochemistry for the Preparation of Cancer Cell Targeting Graphene Oxide. Acs Applied Materials & Interfaces. 7: 18920-3. PMID 26278410 DOI: 10.1021/Acsami.5B06250  0.776
2015 Mei KC, Guo Y, Bai J, Costa PM, Kafa H, Protti A, Hider RC, Al-Jamal KT. Organic Solvent-Free, One-Step Engineering of Graphene-Based Magnetic-Responsive Hybrids Using Design of Experiment-Driven Mechanochemistry. Acs Applied Materials & Interfaces. PMID 26101940 DOI: 10.1021/Acsami.5B03577  0.774
2015 Abbate V, Reelfs O, Hider RC, Pourzand C. Design of novel fluorescent mitochondria-targeted peptides with iron-selective sensing activity. The Biochemical Journal. 469: 357-66. PMID 26008950 DOI: 10.1002/Ajh.24277  0.674
2015 Ma Y, Zhou T, Hider RC. pFe(3+) determination of multidentate ligands by a fluorescence assay. The Analyst. 140: 3603-6. PMID 25857340 DOI: 10.1039/C5An00123D  0.786
2015 Zhou YJ, Liu MS, Osamah AR, Kong XL, Alsam S, Battah S, Xie YY, Hider RC, Zhou T. Hexadentate 3-hydroxypyridin-4-ones with high iron(III) affinity: design, synthesis and inhibition on methicillin resistant Staphylococcus aureus and Pseudomonas strains. European Journal of Medicinal Chemistry. 94: 8-21. PMID 25747496 DOI: 10.1016/J.Ejmech.2015.02.050  0.807
2015 Hider RC, Kong X, Abbate V, Harland R, Conlon K, Luker T. Deferitazole, a new orally active iron chelator. Dalton Transactions (Cambridge, England : 2003). 44: 5197-204. PMID 25687725 DOI: 10.1039/C5Dt00063G  0.689
2015 Pangjit K, Banjerdpongchai R, Phisalaphong C, Fucharoen S, Xie YY, Lu ZD, Hider RC, Srichairatanakool S. Characterisation of a novel oral iron chelator: 1-(N-Acetyl-6-Aminohexyl)-3-Hydroxy-2-Methylpyridin-4-one. The Journal of Pharmacy and Pharmacology. 67: 703-13. PMID 25627251 DOI: 10.1111/Jphp.12373  0.46
2015 Zhou T, Hider RC, Kong X. Mode of iron(III) chelation by hexadentate hydroxypyridinones. Chemical Communications (Cambridge, England). 51: 5614-7. PMID 25611052 DOI: 10.1039/C4Cc10339D  0.521
2015 Zhu CF, Battah S, Kong X, Reeder BJ, Hider RC, Zhou T. Design, synthesis and biological evaluation of 5-aminolaevulinic acid/3-hydroxypyridinone conjugates as potential photodynamic therapeutical agents. Bioorganic & Medicinal Chemistry Letters. 25: 558-61. PMID 25556100 DOI: 10.1016/J.Bmcl.2014.12.018  0.413
2015 Hider RC, Maret W. Iron and zinc sensing in cells and the body. Metallomics : Integrated Biometal Science. 7: 200-1. PMID 25501865 DOI: 10.1039/C4Mt90051K  0.417
2015 Ma MT, Meszaros LK, Paterson BM, Berry DJ, Cooper MS, Ma Y, Hider RC, Blower PJ. Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with (89)Zr(4+): comparison with desferrioxamine-B. Dalton Transactions (Cambridge, England : 2003). 44: 4884-900. PMID 25351250 DOI: 10.1039/C4Dt02978J  0.755
2015 Ma Y, Abbate V, Hider RC. Iron-sensitive fluorescent probes: monitoring intracellular iron pools. Metallomics : Integrated Biometal Science. 7: 212-22. PMID 25315476 DOI: 10.1039/C4Mt00214H  0.835
2015 Chen Y, Chen J, Ma Y, Hider RC. The Synthesis of 5-Functional 3-Hydroxypyridin-4-ones and Their Impact on the Chelating Properties of the Ligands Chemistry Letters. 44: 515-517. DOI: 10.1246/Cl.141133  0.735
2015 Rose C, Driss F, Mansat De Mas V, Beyne-Rauzy O, Gyan E, MA Y, Hider R, Fenaux P, Beaumont C. Markers of Oxidative Stress Do Not Correlate with Labile Plasma Iron Blood in Patients with Myelodysplastic Syndromes Blood. 126: 2149-2149. DOI: 10.1182/Blood.V126.23.2149.2149  0.395
2015 Zhou YJ, Kong XL, Li JP, Ma YM, Hider RC, Zhou T. Novel 3-hydroxypyridin-4-one hexadentate ligand-based polymeric iron chelator: synthesis, characterization and antimicrobial evaluation Medchemcomm. 6: 1620-1625. DOI: 10.1039/C5Md00264H  0.549
2015 Ma Y, Kong X, Abbate V, Hider RC. Synthesis and characterization of novel iron-specific bicyclic fluorescent probes Sensors and Actuators, B: Chemical. 213: 12-19. DOI: 10.1016/J.Snb.2015.02.072  0.839
2015 Ma Y, Hider RC. Novel synthetic approach to fluoro- and amido-disubstituted 3-hydroxypyridin-4-ones Journal of Fluorine Chemistry. 173: 29-34. DOI: 10.1016/J.Jfluchem.2015.02.005  0.749
2014 Ma Y, Kong X, Chen YL, Hider RC. Synthesis and characterizations of pyridazine-based iron chelators. Dalton Transactions (Cambridge, England : 2003). 43: 17120-8. PMID 25311299 DOI: 10.1039/C4Dt02687J  0.832
2014 Kulprachakarn K, Chansiw N, Pangjit K, Phisalaphong C, Fucharoen S, Hider RC, Santitherakul S, Srichairatanakool S. Iron-chelating and anti-lipid peroxidation properties of 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one (CM1) in long-term iron loading β-thalassemic mice. Asian Pacific Journal of Tropical Biomedicine. 4: 663-8. PMID 25183338 DOI: 10.12980/Apjtb.4.2014Apjtb-2014-0155  0.418
2014 Ma Y, Podinovskaia M, Evans PJ, Emma G, Schaible UE, Porter J, Hider RC. A novel method for non-transferrin-bound iron quantification by chelatable fluorescent beads based on flow cytometry. The Biochemical Journal. 463: 351-62. PMID 25093426 DOI: 10.1042/Bj20140795  0.812
2014 Zhang MX, Zhu CF, Zhou YJ, Kong XL, Hider RC, Zhou T. Design, synthesis, and antimicrobial evaluation of hexadentate hydroxypyridinones with high iron(III) affinity. Chemical Biology & Drug Design. 84: 659-68. PMID 24890019 DOI: 10.1111/Cbdd.12358  0.828
2014 Zhou YJ, Zhang MX, Hider RC, Zhou T. In vitro antimicrobial activity of hydroxypyridinone hexadentate-based dendrimeric chelators alone and in combination with norfloxacin. Fems Microbiology Letters. 355: 124-30. PMID 24813898 DOI: 10.1111/1574-6968.12465  0.781
2014 Schmid NB, Giehl RF, Döll S, Mock HP, Strehmel N, Scheel D, Kong X, Hider RC, von Wirén N. Feruloyl-CoA 6'-Hydroxylase1-dependent coumarins mediate iron acquisition from alkaline substrates in Arabidopsis. Plant Physiology. 164: 160-72. PMID 24246380 DOI: 10.1104/Pp.113.228544  0.346
2014 Hider R. Recent developments centered on orally active iron chelators Thalassemia Reports. 4. DOI: 10.4081/Thal.2014.2261  0.473
2014 Swart LD, Hendriks JCM, Vorm LVd, Cabantchik IZ, Evans PJ, Hod EA, Brittenham GM, Furman Y, Janssen MCH, Biemond BJ, MacKenzie MA, Mattijssen VEJM, Origa R, Galanello R, Hider RC, et al. International Comparison Study of Toxic Iron Assays in Patients with Iron Overload Disorders Blood. 124: 4033-4033. DOI: 10.1182/Blood.V124.21.4033.4033  0.452
2014 Xu LL, Hu PP, Kong XL, Hider RC, Zhou T, Dai ZY. 3-Hydroxypyridinone-l-phenylalanine conjugates with antimicrobial and tyrosinase inhibitory activities as potential shrimp preservatives International Journal of Food Science and Technology. 49: 797-803. DOI: 10.1111/Ijfs.12367  0.414
2013 Hider RC, Kong X. Iron: effect of overload and deficiency. Metal Ions in Life Sciences. 13: 229-94. PMID 24470094 DOI: 10.1007/978-94-007-7500-8_8  0.471
2013 Arezes J, Costa M, Vieira I, Dias V, Kong XL, Fernandes R, Vos M, Carlsson A, Rikers Y, Porto G, Rangel M, Hider RC, Pinto JP. Non-transferrin-bound iron (NTBI) uptake by T lymphocytes: evidence for the selective acquisition of oligomeric ferric citrate species. Plos One. 8: e79870. PMID 24278199 DOI: 10.1371/Journal.Pone.0079870  0.765
2013 Zhou T, Hider RC, Jenner P, Campbell B, Hobbs CJ, Rose S, Jairaj M, Tayarani-Binazir KA, Syme A. Design, synthesis and biological evaluation of peptide derivatives of L-dopa as anti-parkinsonian agents. Bioorganic & Medicinal Chemistry Letters. 23: 5279-82. PMID 23973169 DOI: 10.1016/J.Bmcl.2013.08.007  0.509
2013 Dürrenberger F, Abbate V, Ma Y, Arno MC, Jaiash D, Parmar A, Marshall V, Latunde-Dada GO, Zimmermann T, Senn D, Altermatt P, Manolova V, Hider RC, Bansal SS. Functional characterization of fluorescent hepcidin. Bioconjugate Chemistry. 24: 1527-32. PMID 23888876 DOI: 10.1021/Bc400121X  0.809
2013 Li DF, Hu PP, Liu MS, Kong XL, Zhang JC, Hider RC, Zhou T. Design and synthesis of hydroxypyridinone-L-phenylalanine conjugates as potential tyrosinase inhibitors. Journal of Agricultural and Food Chemistry. 61: 6597-603. PMID 23802151 DOI: 10.1021/Jf401585F  0.721
2013 Zhu CF, Qiu DH, Kong XL, Hider RC, Zhou T. Synthesis and in-vitro antimicrobial evaluation of a high-affinity iron chelator in combination with chloramphenicol. The Journal of Pharmacy and Pharmacology. 65: 512-20. PMID 23488779 DOI: 10.1111/Jphp.12013  0.783
2013 Gehrke SS, Pinto EG, Steverding D, Pleban K, Tempone AG, Hider RC, Wagner GK. Conjugation to 4-aminoquinoline improves the anti-trypanosomal activity of Deferiprone-type iron chelators Bioorganic and Medicinal Chemistry. 21: 805-813. PMID 23266185 DOI: 10.1016/J.Bmc.2012.11.009  0.639
2013 Hider RC, Kong X. Iron speciation in the cytosol: an overview. Dalton Transactions (Cambridge, England : 2003). 42: 3220-9. PMID 23232973 DOI: 10.1039/C2Dt32149A  0.479
2013 Ma Y, Xie Y, Hider RC. A novel fluorescence method for determination of pFe3+. The Analyst. 138: 96-9. PMID 23085963 DOI: 10.1039/C2An36186H  0.772
2013 Hider R, Kong X, Luker T, Conlon K. SPD602 Is a Selective Iron Chelator Which Is Able To Mobilise The Non-Transferrin-Bound Iron Pool Blood. 122: 1673-1673. DOI: 10.1182/Blood.V122.21.1673.1673  0.487
2013 Zhu J, Li D, Kong X, Hider RC, Zhou T. Coordination chemistry of a bis(3-hydroxypyran-4-one) with iron and copper Journal of Coordination Chemistry. 66: 2957-2969. DOI: 10.1080/00958972.2013.818670  0.517
2012 Chen YL, Doltsinis NL, Hider RC, Barlow DJ. Prediction of Absolute Hydroxyl pKa Values for 3-Hydroxypyridin-4-ones. The Journal of Physical Chemistry Letters. 3: 2980-5. PMID 26292237 DOI: 10.1021/Jz301061M  0.713
2012 Chen YL, Barlow DJ, Kong XL, Ma YM, Hider RC. Prediction of 3-hydroxypyridin-4-one (HPO) log K1 values for Fe(III). Dalton Transactions (Cambridge, England : 2003). 41: 10784-91. PMID 22854534 DOI: 10.1039/C2Dt31254A  0.78
2012 Ma Y, Zhou T, Kong X, Hider RC. Chelating agents for the treatment of systemic iron overload. Current Medicinal Chemistry. 19: 2816-27. PMID 22455586 DOI: 10.2174/092986712800609724  0.548
2012 Chen YL, Barlow DJ, Kong XL, Ma YM, Hider RC. Prediction of 3-hydroxypyridin-4-one (HPO) hydroxyl pKa values. Dalton Transactions (Cambridge, England : 2003). 41: 6549-57. PMID 22395734 DOI: 10.1039/C2Dt12396G  0.77
2012 Zhou T, Ma Y, Kong X, Hider RC. Design of iron chelators with therapeutic application. Dalton Transactions (Cambridge, England : 2003). 41: 6371-89. PMID 22391807 DOI: 10.1016/S0010-8545(02)00050-4  0.82
2012 Ma Y, Roy S, Kong X, Chen Y, Liu D, Hider RC. Design and synthesis of fluorinated iron chelators for metabolic study and brain uptake. Journal of Medicinal Chemistry. 55: 2185-95. PMID 22339047 DOI: 10.1021/Jm201475U  0.821
2012 Evans RW, Kong X, Hider RC. Iron mobilization from transferrin by therapeutic iron chelating agents. Biochimica Et Biophysica Acta. 1820: 282-90. PMID 22155077 DOI: 10.1016/J.Bbagen.2011.11.007  0.627
2012 Lomer MC, Cook WB, Jan-Mohamed HJ, Hutchinson C, Liu DY, Hider RC, Powell JJ. Iron requirements based upon iron absorption tests are poorly predicted by haematological indices in patients with inactive inflammatory bowel disease. The British Journal of Nutrition. 107: 1806-11. PMID 22152498 DOI: 10.1017/S0007114511004971  0.353
2012 Xie Y, Liu M, Hu P, Kong X, Qiu D, Xu J, Hider RC, Zhou T. Synthesis, physico-chemical properties, and antimicrobial evaluation of a new series of iron(III) hexadentate chelators Medicinal Chemistry Research. 22: 2351-2359. DOI: 10.1007/S00044-012-0229-1  0.782
2011 Xu B, Kong XL, Zhou T, Qiu DH, Chen YL, Liu MS, Yang RH, Hider RC. Synthesis, iron(III)-binding affinity and in vitro evaluation of 3-hydroxypyridin-4-one hexadentate ligands as potential antimicrobial agents. Bioorganic & Medicinal Chemistry Letters. 21: 6376-80. PMID 21937227 DOI: 10.1016/J.Bmcl.2011.08.097  0.836
2011 Hider RC, Kong XL. Glutathione: a key component of the cytoplasmic labile iron pool. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 24: 1179-87. PMID 21769609 DOI: 10.1007/S10534-011-9476-8  0.764
2011 Rahmioglu N, Heaton J, Clement G, Gill R, Surdulescu G, Zlobecka K, Hodgkiss D, Ma Y, Hider RC, Smith NW, Ahmadi KR. Genetic epidemiology of induced CYP3A4 activity. Pharmacogenetics and Genomics. 21: 642-51. PMID 21750469 DOI: 10.1097/Fpc.0B013E3283498Ecf  0.728
2011 Zhou T, Winkelmann G, Dai ZY, Hider RC. Design of clinically useful macromolecular iron chelators. The Journal of Pharmacy and Pharmacology. 63: 893-903. PMID 21635254 DOI: 10.1111/J.2042-7158.2011.01291.X  0.514
2011 Berry DJ, Ma Y, Ballinger JR, Tavaré R, Koers A, Sunassee K, Zhou T, Nawaz S, Mullen GE, Hider RC, Blower PJ. Efficient bifunctional gallium-68 chelators for positron emission tomography: tris(hydroxypyridinone) ligands. Chemical Communications (Cambridge, England). 47: 7068-70. PMID 21623436 DOI: 10.1039/C1Cc12123E  0.763
2011 Baek JH, Reiter CE, Manalo DJ, Buehler PW, Hider RC, Alayash AI. Induction of hypoxia inducible factor (HIF-1α) in rat kidneys by iron chelation with the hydroxypyridinone, CP94. Biochimica Et Biophysica Acta. 1809: 262-8. PMID 21558026 DOI: 10.1016/J.Bbagrm.2011.04.010  0.395
2011 Yoshimura E, Kohdr H, Mori S, Hider RC. The binding of aluminum to mugineic acid and related compounds as studied by potentiometric titration. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 24: 723-7. PMID 21350950 DOI: 10.1007/S10534-011-9424-7  0.308
2011 Hider RC, Roy S, Ma YM, Le Kong X, Preston J. The potential application of iron chelators for the treatment of neurodegenerative diseases. Metallomics : Integrated Biometal Science. 3: 239-49. PMID 21344071 DOI: 10.1039/C0Mt00087F  0.653
2011 Staff K, Brown MB, Chilcott RP, Hider RC, Jones SA, Kong XL. Ga(III) complexes-The effect of metal coordination on potential systemic absorption after topical exposure Toxicology Letters. 202: 155-160. PMID 21315140 DOI: 10.1016/J.Toxlet.2011.01.017  0.742
2011 Gaeta A, Molina-Holgado F, Kong XL, Salvage S, Fakih S, Francis PT, Williams RJ, Hider RC. Synthesis, physical-chemical characterisation and biological evaluation of novel 2-amido-3-hydroxypyridin-4(1H)-ones: Iron chelators with the potential for treating Alzheimer's disease. Bioorganic & Medicinal Chemistry. 19: 1285-97. PMID 21236688 DOI: 10.1016/J.Bmc.2010.12.007  0.764
2011 Liu B, Moloney A, Meehan S, Morris K, Thomas SE, Serpell LC, Hider R, Marciniak SJ, Lomas DA, Crowther DC. Iron promotes the toxicity of amyloid beta peptide by impeding its ordered aggregation. The Journal of Biological Chemistry. 286: 4248-56. PMID 21147772 DOI: 10.1074/Jbc.M110.158980  0.434
2011 Qiu DH, Huang ZL, Zhou T, Shen C, Hider RC. In vitro inhibition of bacterial growth by iron chelators. Fems Microbiology Letters. 314: 107-11. PMID 21114684 DOI: 10.1111/J.1574-6968.2010.02153.X  0.5
2010 Macdougall IC, Malyszko J, Hider RC, Bansal SS. Current status of the measurement of blood hepcidin levels in chronic kidney disease. Clinical Journal of the American Society of Nephrology : Cjasn. 5: 1681-9. PMID 20724518 DOI: 10.2215/Cjn.05990809  0.777
2010 Hider RC, Silva AM, Podinovskaia M, Ma Y. Monitoring the efficiency of iron chelation therapy: the potential of nontransferrin-bound iron. Annals of the New York Academy of Sciences. 1202: 94-9. PMID 20712779 DOI: 10.1111/J.1749-6632.2010.05573.X  0.813
2010 Staff K, Brown MB, Hider RC, Kong XL, Friden P, Jones SA. Recovering Ga(III) from coordination complexes using pyridine 2,6-dicarboxylic acid chelation ion chromatography Biomedical Chromatography. 24: 1015-1022. PMID 20700886 DOI: 10.1002/Bmc.1402  0.558
2010 Roy S, Preston JE, Hider RC, Ma YM. Glucosylated deferiprone and its brain uptake: implications for developing glucosylated hydroxypyridinone analogues intended to cross the blood-brain barrier. Journal of Medicinal Chemistry. 53: 5886-9. PMID 20684616 DOI: 10.1021/Jm100380K  0.565
2010 Zhou T, Hider RC, Jenner P, Campbell B, Hobbs CJ, Rose S, Jairaj M, Tayarani-Binazir KA, Syme A. Design, synthesis and biological evaluation of L-dopa amide derivatives as potential prodrugs for the treatment of Parkinson's disease. European Journal of Medicinal Chemistry. 45: 4035-42. PMID 20646792 DOI: 10.1016/J.Ejmech.2010.05.062  0.485
2010 Evans P, Kayyali R, Hider RC, Eccleston J, Porter JB. Mechanisms for the shuttling of plasma non-transferrin-bound iron (NTBI) onto deferoxamine by deferiprone. Translational Research : the Journal of Laboratory and Clinical Medicine. 156: 55-67. PMID 20627190 DOI: 10.1016/J.Trsl.2010.05.002  0.463
2010 Lan Y, Langlet-Bertin B, Abbate V, Vermeer LS, Kong X, Sullivan KE, Leborgne C, Scherman D, Hider RC, Drake AF, Bansal SS, Kichler A, Mason AJ. Incorporation of 2,3-diaminopropionic acid into linear cationic amphipathic peptides produces pH-sensitive vectors. Chembiochem : a European Journal of Chemical Biology. 11: 1266-72. PMID 20480482 DOI: 10.1002/Cbic.201000073  0.766
2010 Piyamongkol S, Ma YM, Kong XL, Liu ZD, Aytemir MD, van der Helm D, Hider RC. Amido-3-hydroxypyridin-4-ones as iron(III) ligands. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 6374-81. PMID 20397153 DOI: 10.1002/Chem.200902455  0.787
2010 Bansal SS, Abbate V, Bomford A, Halket JM, Macdougall IC, Thein SL, Hider RC. Quantitation of hepcidin in serum using ultra-high-pressure liquid chromatography and a linear ion trap mass spectrometer. Rapid Communications in Mass Spectrometry : Rcm. 24: 1251-9. PMID 20391595 DOI: 10.1002/Rcm.4512  0.778
2010 Hider RC, Kong X. Chemistry and biology of siderophores. Natural Product Reports. 27: 637-57. PMID 20376388 DOI: 10.1039/B906679A  0.471
2010 Nunes A, Podinovskaia M, Leite A, Gameiro P, Zhou T, Ma Y, Kong X, Schaible UE, Hider RC, Rangel M. Fluorescent 3-hydroxy-4-pyridinone hexadentate iron chelators: intracellular distribution and the relevance to antimycobacterial properties. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 15: 861-77. PMID 20364296 DOI: 10.1007/S00775-010-0650-1  0.826
2010 Hider RC. Charge states of deferasirox-ferric iron complexes. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 55: 614-5. PMID 20189051 DOI: 10.1053/J.Ajkd.2009.10.065  0.384
2010 Fernandes SS, Nunes A, Gomes AR, de Castro B, Hider RC, Rangel M, Appelberg R, Gomes MS. Identification of a new hexadentate iron chelator capable of restricting the intramacrophagic growth of Mycobacterium avium. Microbes and Infection / Institut Pasteur. 12: 287-94. PMID 20097303 DOI: 10.1016/J.Micinf.2010.01.003  0.438
2010 Kerkweg U, Pamp K, Fieker J, Petrat F, Hider RC, de Groot H. Release of redox-active iron by muscle crush trauma: no liberation into the circulation. Shock (Augusta, Ga.). 33: 513-8. PMID 19823114 DOI: 10.1097/Shk.0B013E3181C4F56E  0.406
2009 Kroot JJ, Kemna EH, Bansal SS, Busbridge M, Campostrini N, Girelli D, Hider RC, Koliaraki V, Mamalaki A, Olbina G, Tomosugi N, Tselepis C, Ward DG, Ganz T, Hendriks JC, et al. Results of the first international round robin for the quantification of urinary and plasma hepcidin assays: need for standardization. Haematologica. 94: 1748-52. PMID 19996119 DOI: 10.3324/Haematol.2009.010322  0.742
2009 Ma YM, Hider RC. The selective quantification of iron by hexadentate fluorescent probes Bioorganic and Medicinal Chemistry. 17: 8093-8101. PMID 19853460 DOI: 10.1016/J.Bmc.2009.09.052  0.448
2009 Silva AM, Kong X, Parkin MC, Cammack R, Hider RC. Iron(III) citrate speciation in aqueous solution. Dalton Transactions (Cambridge, England : 2003). 8616-25. PMID 19809738 DOI: 10.1039/B910970F  0.763
2009 Rival T, Page RM, Chandraratna DS, Sendall TJ, Ryder E, Liu B, Lewis H, Rosahl T, Hider R, Camargo LM, Shearman MS, Crowther DC, Lomas DA. Fenton chemistry and oxidative stress mediate the toxicity of the beta-amyloid peptide in a Drosophila model of Alzheimer's disease. The European Journal of Neuroscience. 29: 1335-47. PMID 19519625 DOI: 10.1111/J.1460-9568.2009.06701.X  0.326
2009 Silva AM, Hider RC. Influence of non-enzymatic post-translation modifications on the ability of human serum albumin to bind iron. Implications for non-transferrin-bound iron speciation. Biochimica Et Biophysica Acta. 1794: 1449-58. PMID 19505594 DOI: 10.1016/J.Bbapap.2009.06.003  0.466
2009 Madlova M, Jones SA, Zwerschke I, Ma Y, Hider RC, Forbes B. Poly(vinyl alcohol) nanoparticle stability in biological media and uptake in respiratory epithelial cell layers in vitro. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 72: 437-43. PMID 19462480 DOI: 10.1016/J.Ejpb.2009.01.009  0.539
2009 Gul MO, Jones SA, Dailey LA, Nacer H, Ma Y, Sadouki F, Hider R, Araman A, Forbes B. A poly(vinyl alcohol) nanoparticle platform for kinetic studies of inhaled particles. Inhalation Toxicology. 21: 631-40. PMID 19459777 DOI: 10.1080/08958370802353435  0.767
2009 Bansal SS, Halket JM, Fusova J, Bomford A, Simpson RJ, Vasavda N, Thein SL, Hider RC. Quantification of hepcidin using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 23: 1531-42. PMID 19399775 DOI: 10.1002/Rcm.4033  0.742
2009 Silva AM, Kong X, Hider RC. Determination of the pKa value of the hydroxyl group in the alpha-hydroxycarboxylates citrate, malate and lactate by 13C NMR: implications for metal coordination in biological systems. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 22: 771-8. PMID 19288211 DOI: 10.1007/S10534-009-9224-5  0.698
2009 Bansal SS, Halket JM, Bomford A, Simpson RJ, Vasavda N, Thein SL, Hider RC. Quantitation of hepcidin in human urine by liquid chromatography-mass spectrometry. Analytical Biochemistry. 384: 245-53. PMID 18951868 DOI: 10.1016/J.Ab.2008.09.045  0.74
2009 Fakih S, Podinovskaia M, Kong X, Schaible UE, Collins HL, Hider RC. Monitoring intracellular labile iron pools: A novel fluorescent iron(III) sensor as a potential non-invasive diagnosis tool. Journal of Pharmaceutical Sciences. 98: 2212-26. PMID 18823046 DOI: 10.1002/Jps.21583  0.477
2009 Laftah AH, Latunde-Dada GO, Fakih S, Hider RC, Simpson RJ, McKie AT. Haem and folate transport by proton-coupled folate transporter/haem carrier protein 1 (SLC46A1). The British Journal of Nutrition. 101: 1150-6. PMID 18782461 DOI: 10.1017/S0007114508066762  0.641
2009 Rangel M, Gameiro P, Leite A, Nunes A, Zhou T, Ma Y, Hider R. Insight on the Diverse Cellular Pathways of Two Novel Chelators from Liposome Partition Studies Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.656  0.481
2008 Hider RC, Ma Y, Molina-Holgado F, Gaeta A, Roy S. Iron chelation as a potential therapy for neurodegenerative disease. Biochemical Society Transactions. 36: 1304-8. PMID 19021545 DOI: 10.1042/Bst0361304  0.806
2008 Fakih S, Podinovskaia M, Kong X, Collins HL, Schaible UE, Hider RC. Targeting the lysosome: fluorescent iron(III) chelators to selectively monitor endosomal/lysosomal labile iron pools. Journal of Medicinal Chemistry. 51: 4539-52. PMID 18624421 DOI: 10.1021/Jm8001247  0.464
2008 Zhou T, Kong XL, Liu ZD, Liu DY, Hider RC. Synthesis and iron(III)-chelating properties of novel 3-hydroxypyridin-4-one hexadentate ligand-containing copolymers. Biomacromolecules. 9: 1372-80. PMID 18373358 DOI: 10.1021/Bm701122U  0.825
2008 Molina-Holgado F, Gaeta A, Francis PT, Williams RJ, Hider RC. Neuroprotective actions of deferiprone in cultured cortical neurones and SHSY-5Y cells. Journal of Neurochemistry. 105: 2466-76. PMID 18331585 DOI: 10.1111/J.1471-4159.2008.05332.X  0.36
2008 Kong X, Neubert H, Zhou T, Liu ZD, Hider RC. MALDI mass spectrometric determination of dendritic iron chelation stoichiometries and conditional affinity constants. Journal of Mass Spectrometry : Jms. 43: 617-22. PMID 18286664 DOI: 10.1002/Jms.1357  0.699
2008 Faas L, Venkatasamy R, Hider RC, Young AR, Soumyanath A. In vivo evaluation of piperine and synthetic analogues as potential treatments for vitiligo using a sparsely pigmented mouse model. The British Journal of Dermatology. 158: 941-50. PMID 18284389 DOI: 10.1111/J.1365-2133.2008.08464.X  0.757
2008 Hutchinson C, Conway RE, Bomford A, Hider RC, Powell JJ, Geissler CA. Post-prandial iron absorption in humans: comparison between HFE genotypes and iron deficiency anaemia. Clinical Nutrition (Edinburgh, Scotland). 27: 258-63. PMID 18276042 DOI: 10.1016/J.Clnu.2007.12.007  0.462
2008 Ayres JG, Borm P, Cassee FR, Castranova V, Donaldson K, Ghio A, Harrison RM, Hider R, Kelly F, Kooter IM, Marano F, Maynard RL, Mudway I, Nel A, Sioutas C, et al. Evaluating the toxicity of airborne particulate matter and nanoparticles by measuring oxidative stress potential--a workshop report and consensus statement. Inhalation Toxicology. 20: 75-99. PMID 18236225 DOI: 10.1080/08958370701665517  0.464
2008 Reeder BJ, Hider RC, Wilson MT. Iron chelators can protect against oxidative stress through ferryl heme reduction Free Radical Biology and Medicine. 44: 264-273. PMID 18215735 DOI: 10.1016/J.Freeradbiomed.2007.08.006  0.471
2008 Devanur LD, Evans RW, Evans PJ, Hider RC. Chelator-facilitated removal of iron from transferrin: relevance to combined chelation therapy. The Biochemical Journal. 409: 439-47. PMID 17919118 DOI: 10.1042/Bj20070823  0.636
2008 Evans RW, Rafique R, Zarea A, Rapisarda C, Cammack R, Evans PJ, Porter JB, Hider RC. Nature of non-transferrin-bound iron: studies on iron citrate complexes and thalassemic sera. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 13: 57-74. PMID 17906879 DOI: 10.1007/S00775-007-0297-8  0.627
2008 Dehkordi LS, Liu ZD, Hider RC. Basic 3-hydroxypyridin-4-ones: potential antimalarial agents. European Journal of Medicinal Chemistry. 43: 1035-47. PMID 17869385 DOI: 10.1016/J.Ejmech.2007.07.011  0.664
2008 Devanur LD, Neubert H, Hider RC. The fenton activity of iron(III) in the presence of deferiprone. Journal of Pharmaceutical Sciences. 97: 1454-67. PMID 17724662 DOI: 10.1002/Jps.21039  0.445
2008 Sayani F, Bansal S, Evans P, Weljie A, Hider RC, Porter JB. Disease Specific Modulation of Serum Hepcidin: Impact of GDF-15 and Iron Metabolism Markers in Thalassemia Major, Thalassemia Intermedia and Sickle Cell Disease: A Univariate and Multivariate Analysis. Blood. 112: 3850-3850. DOI: 10.1182/Blood.V112.11.3850.3850  0.775
2008 Kroot JJ, Kemna EH, Bansal S, Busbridge M, Campostrini N, Girelli D, Hider RC, Koliaraki V, Mamalaki A, Olbina G, Tomosugi N, Tselepis C, Ward DG, Ganz T, Hendriks JC, et al. Results of the First International Round Robin for the Quantification of Urinary and Plasma Hepcidin: Need for Standardization Blood. 112: 120-120. DOI: 10.1182/Blood.V112.11.120.120  0.728
2008 Liu DY, Liu ZD, Lu SL, Hider RC. Hydrolytic and Metabolic Characteristics of the Esters of1-(3′-Hydroxypropyl)-2-methyl-3-hydroxypyridin-4-one (CP41), Potentially Useful Iron Chelators Pharmacology & Toxicology. 86: 228-233. DOI: 10.1034/J.1600-0773.2000.Pto860506.X  0.65
2007 Ma Y, Liu Z, Hider RC, Petrat F. Determination of the labile iron pool of human lymphocytes using the fluorescent probe, CP655. Analytical Chemistry Insights. 2: 61-7. PMID 19662178 DOI: 10.4137/Aci.S0  0.809
2007 Kong X, Zhou T, Liu Z, Hider RC. pH indicator titration: a novel fast pKa determination method. Journal of Pharmaceutical Sciences. 96: 2777-83. PMID 17621680 DOI: 10.1002/Jps.20959  0.368
2007 Lin Z, Liao Y, Venkatasamy R, Hider RC, Soumyanath A. Amides from Piper nigrum L. with dissimilar effects on melanocyte proliferation in-vitro. The Journal of Pharmacy and Pharmacology. 59: 529-36. PMID 17430636 DOI: 10.1211/Jpp.59.4.0007  0.685
2007 Diggle SP, Matthijs S, Wright VJ, Fletcher MP, Chhabra SR, Lamont IL, Kong X, Hider RC, Cornelis P, Cámara M, Williams P. The Pseudomonas aeruginosa 4-quinolone signal molecules HHQ and PQS play multifunctional roles in quorum sensing and iron entrapment. Chemistry & Biology. 14: 87-96. PMID 17254955 DOI: 10.1016/j.chembiol.2006.11.014  0.353
2006 Soumyanath A, Venkatasamy R, Joshi M, Faas L, Adejuyigbe B, Drake AF, Hider RC, Young AR. UV irradiation affects melanocyte stimulatory activity and protein binding of piperine. Photochemistry and Photobiology. 82: 1541-8. PMID 17387768 DOI: 10.1562/2006-04-21-Ra-882  0.757
2006 Merkofer M, Kissner R, Hider RC, Brunk UT, Koppenol WH. Fenton chemistry and iron chelation under physiologically relevant conditions: Electrochemistry and kinetics. Chemical Research in Toxicology. 19: 1263-9. PMID 17040095 DOI: 10.1021/Tx060101W  0.478
2006 Zhou T, Neubert H, Liu DY, Liu ZD, Ma YM, Kong XL, Luo W, Mark S, Hider RC. Iron binding dendrimers: a novel approach for the treatment of haemochromatosis. Journal of Medicinal Chemistry. 49: 4171-82. PMID 16821777 DOI: 10.1021/Jm0600949  0.832
2006 Ren Y, Houghton P, Hider RC. Relevant activities of extracts and constituents of animals used in traditional Chinese medicine for central nervous system effects associated with Alzheimer's disease. The Journal of Pharmacy and Pharmacology. 58: 989-96. PMID 16805960 DOI: 10.1211/Jpp.58.7.0015  0.308
2006 Conway RE, Geissler CA, Hider RC, Thompson RP, Powell JJ. Serum iron curves can be used to estimate dietary iron bioavailability in humans. The Journal of Nutrition. 136: 1910-4. PMID 16772458 DOI: 10.1093/Jn/136.7.1910  0.425
2006 Kong X, Zhou T, Neubert H, Liu Z, Hider RC. 3-Hydroxy-2-(5-hydroxypentyl)-4H-chromen-4-one: a bidentate or tridentate iron(III) ligand? Journal of Medicinal Chemistry. 49: 3028-31. PMID 16686545 DOI: 10.1021/Jm050905T  0.506
2006 Barral K, Balzarini J, Neyts J, De Clercq E, Hider RC, Camplo M. Synthesis and antiviral evaluation of cyclic and acyclic 2-methyl-3-hydroxy-4-pyridinone nucleoside derivatives. Journal of Medicinal Chemistry. 49: 43-50. PMID 16392791 DOI: 10.1021/Jm0504306  0.443
2006 Ma Y, de Groot H, Liu Z, Hider RC, Petrat F. Chelation and determination of labile iron in primary hepatocytes by pyridinone fluorescent probes. The Biochemical Journal. 395: 49-55. PMID 16336208 DOI: 10.1042/Bj20051496  0.812
2006 Molina-Holgado F, Williams RJ, Gaeta A, Rose S, Hider RC, Domeney A, Hagan RM, Francis PT. P4-386 : Neuroprotective actions of an iron chelator against Alzheimer’s disease-relevant insults Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.2127  0.403
2005 Hider RC, Zhou T. The design of orally active iron chelators. Annals of the New York Academy of Sciences. 1054: 141-54. PMID 16339660 DOI: 10.1196/Annals.1345.017  0.543
2005 Zhou T, Liu ZD, Neubert H, Kong XL, Ma YM, Hider RC. High affinity iron(III) scavenging by a novel hexadentate 3-hydroxypyridin-4-one-based dendrimer: synthesis and characterization. Bioorganic & Medicinal Chemistry Letters. 15: 5007-11. PMID 16153843 DOI: 10.1016/J.Bmcl.2005.08.008  0.826
2005 Shayeghi M, Latunde-Dada GO, Oakhill JS, Laftah AH, Takeuchi K, Halliday N, Khan Y, Warley A, McCann FE, Hider RC, Frazer DM, Anderson GJ, Vulpe CD, Simpson RJ, McKie AT. Identification of an intestinal heme transporter. Cell. 122: 789-801. PMID 16143108 DOI: 10.1016/J.Cell.2005.06.025  0.704
2005 Berndt UE, Zhou T, Hider RC, Liu ZD, Neubert H. Structural characterization of chelator-terminated dendrimers and their synthetic intermediates by mass spectrometry. Journal of Mass Spectrometry : Jms. 40: 1203-14. PMID 16127663 DOI: 10.1002/Jms.899  0.604
2005 Ma Y, Luo W, Camplo M, Liu Z, Hider RC. Novel iron-specific fluorescent probes. Bioorganic & Medicinal Chemistry Letters. 15: 3450-2. PMID 15950474 DOI: 10.1016/J.Bmcl.2005.05.010  0.792
2005 Jacobs EM, Hendriks JC, van Tits BL, Evans PJ, Breuer W, Liu DY, Jansen EH, Jauhiainen K, Sturm B, Porter JB, Scheiber-Mojdehkar B, von Bonsdorff L, Cabantchik ZI, Hider RC, Swinkels DW. Results of an international round robin for the quantification of serum non-transferrin-bound iron: Need for defining standardization and a clinically relevant isoform. Analytical Biochemistry. 341: 241-50. PMID 15907869 DOI: 10.1016/J.Ab.2005.03.008  0.418
2005 Piyamongkol S, Zhou T, Liu ZD, Khodr HH, Hider RC. Design and characterisation of novel hexadentate 3-hydroxypyridin-4-one ligands Tetrahedron Letters. 46: 1333-1336. DOI: 10.1016/J.Tetlet.2004.12.115  0.651
2004 Hider RC, Yoshimura E, Khodr H, Von Wirén N. Competition or complementation: the iron-chelating abilities of nicotianamine and phytosiderophores. The New Phytologist. 164: 204-208. PMID 33873550 DOI: 10.1111/J.1469-8137.2004.01209.X  0.465
2004 Ma Y, Luo W, Quinn PJ, Liu Z, Hider RC. Design, synthesis, physicochemical properties, and evaluation of novel iron chelators with fluorescent sensors. Journal of Medicinal Chemistry. 47: 6349-62. PMID 15566304 DOI: 10.1021/Jm049751S  0.813
2004 Hutchinson C, Al-Ashgar W, Liu DY, Hider R, Powell JJ, Geissler C. Oral ferrous sulphate leads to a marked increase in pro‐oxidant nontransferrin‐bound iron European Journal of Clinical Investigation. 34: 782-784. PMID 15530152 DOI: 10.1111/J.1365-2362.2004.01416.X  0.438
2004 Luo W, Ma YM, Quinn PJ, Hider RC, Liu ZD. Design, synthesis and properties of novel iron(III)-specific fluorescent probes. The Journal of Pharmacy and Pharmacology. 56: 529-36. PMID 15099448 DOI: 10.1211/0022357023196  0.823
2004 Venkatasamy R, Faas L, Young AR, Raman A, Hider RC. Effects of piperine analogues on stimulation of melanocyte proliferation and melanocyte differentiation. Bioorganic & Medicinal Chemistry. 12: 1905-20. PMID 15051059 DOI: 10.1016/J.Bmc.2004.01.036  0.601
2004 Gaboriau F, Chantrel-Groussard K, Rakba N, Loyer P, Pasdeloup N, Hider RC, Brissot P, Lescoat G. Iron mobilization, cytoprotection, and inhibition of cell proliferation in normal and transformed rat hepatocyte cultures by the hydroxypyridinone CP411, compared to CP20: a biological and physicochemical study. Biochemical Pharmacology. 67: 1479-87. PMID 15041465 DOI: 10.1016/J.Bcp.2003.12.019  0.434
2004 Zhou T, Hider RC, Liu ZD, Neubert H. Iron(III)-selective dendritic chelators Tetrahedron Letters. 45: 9393-9396. DOI: 10.1016/J.Tetlet.2004.10.110  0.711
2004 Merkofer M, Kissner R, Hider RC, Koppenol WH. Redox Properties of the Iron Complexes of Orally Active Iron Chelators CP20, CP502, CP509, and ICL670 Helvetica Chimica Acta. 87: 3021-3034. DOI: 10.1002/Hlca.200490272  0.455
2003 Fischer R, Longo F, Nielsen P, Engelhardt R, Hider RC, Piga A. Monitoring long-term efficacy of iron chelation therapy by deferiprone and desferrioxamine in patients with beta-thalassaemia major: application of SQUID biomagnetic liver susceptometry. British Journal of Haematology. 121: 938-48. PMID 12786807 DOI: 10.1046/J.1365-2141.2003.04297.X  0.409
2003 Hider RC, Liu ZD. Emerging understanding of the advantage of small molecules such as hydroxypyridinones in the treatment of iron overload. Current Medicinal Chemistry. 10: 1051-64. PMID 12678676 DOI: 10.2174/0929867033457629  0.681
2003 Liu DY, Liu ZD, Piyamongkol S, Lu SL, Hider RC. Characterization of two isomeric beta-d-glucosiduronic acids derived from 1,2-diethyl-3-hydroxypyridin-4-one (CP94) in rat liver homogenate incubates. The Journal of Pharmacy and Pharmacology. 54: 951-7. PMID 12162714 DOI: 10.1211/002235702760089072  0.576
2002 Liu ZD, Liu DY, Hider RC. Iron chelator chemistry. Advances in Experimental Medicine and Biology. 509: 141-66. PMID 12572993 DOI: 10.1007/978-1-4615-0593-8_8  0.685
2002 Liu DY, Liu ZD, Hider RC. Oral iron chelators--development and application. Best Practice & Research. Clinical Haematology. 15: 369-84. PMID 12401312 DOI: 10.1053/Beha.2002.0209  0.686
2002 Khodr HH, Hider RC, Duhme-Klair AK. The iron-binding properties of aminochelin, the mono(catecholamide) siderophore of Azotobacter vinelandii Journal of Biological Inorganic Chemistry. 7: 891-896. PMID 12203027 DOI: 10.1007/S00775-002-0375-X  0.361
2002 Loréal O, Turlin B, Pigeon C, Moisan A, Ropert M, Morice P, Gandon Y, Jouanolle AM, Vérin M, Hider RC, Yoshida K, Brissot P. Aceruloplasminemia: New clinical, pathophysiological and therapeutic insights Journal of Hepatology. 36: 851-856. PMID 12044538 DOI: 10.1016/S0168-8278(02)00042-9  0.426
2002 Moridani MY, Tilbrook GS, Khodr HH, Hider RC. Synthesis and physicochemical assessment of novel 2-substituted 3-hydroxypyridin-4-ones, novel iron chelators Journal of Pharmacy and Pharmacology. 54: 349-364. PMID 11902801 DOI: 10.1211/0022357021778592  0.459
2002 Hider RC. Nature of nontransferrin-bound iron. European Journal of Clinical Investigation. 32: 50-4. PMID 11886432 DOI: 10.1046/J.1365-2362.2002.0320S1050.X  0.462
2002 Kooistra MP, Kersting S, Gosriwatana I, Lu S, Nijhoff-Schutte J, Hider R, Marx JJM. Nontransferrin-bound iron in the plasma of haemodialysis patients after intravenous iron saccharate infusion European Journal of Clinical Investigation. 32: 36-41. PMID 11886430 DOI: 10.1046/J.1365-2362.2002.0320S1036.X  0.468
2002 Rooyakkers TM, Stroes ESG, Kooistra MP, Faassen EEv, Hider R, Rabelink TJ, Marx JJM. Ferric saccharate induces oxygen radical stress and endothelial dysfunction in vivo European Journal of Clinical Investigation. 32: 9-16. PMID 11886426 DOI: 10.1046/J.1365-2362.2002.0320S1009.X  0.377
2002 Marx JJM, Hider R. Iron: an essential but potentially harmful nutrient. European Journal of Clinical Investigation. 32: 1-2. PMID 11886424 DOI: 10.1046/J.1365-2362.2002.0320S1001.X  0.455
2002 Liu ZD, Kayyali R, Hider RC, Porter JB, Theobald AE. Design, synthesis, and evaluation of novel 2-substituted 3-hydroxypyridin-4-ones: structure-activity investigation of metalloenzyme inhibition by iron chelators. Journal of Medicinal Chemistry. 45: 631-9. PMID 11806714 DOI: 10.1021/Jm010817I  0.659
2002 Zanninelli G, Loréal O, Brissot P, Konijn AM, Slotki IN, Hider RC, Ioav Cabantchik Z. The labile iron pool of hepatocytes in chronic and acute iron overload and chelator-induced iron deprivation. Journal of Hepatology. 36: 39-46. PMID 11804662 DOI: 10.1016/S0168-8278(01)00222-7  0.461
2002 Liu ZD, Hider RC. Design of clinically useful iron(III)-selective chelators. Medicinal Research Reviews. 22: 26-64. PMID 11746175 DOI: 10.1002/Med.1027  0.693
2002 YOSHIMURA E, LIU ZD, KHODR H, HIDER RC. Purity of commercial morin products and their spectrophotometric characterisation. Bunseki Kagaku. 51: 979-982. DOI: 10.2116/Bunsekikagaku.51.979  0.552
2002 Neubert H, Hider RC, Cowan DA. Speciation of Fe(III)-chelate complexes by electrospray ionization ion trap and laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry Rapid Communications in Mass Spectrometry. 16: 1556-1561. DOI: 10.1002/Rcm.756  0.347
2001 Hider R. Design of therapeutic chelating agents. Biochemical Society Transactions. 30: 751-754. PMID 12196186 DOI: 10.1042/Bst0300751  0.31
2001 Kayyali R, Porter JB, Liu ZD, Davies NA, Nugent JH, Cooper CE, Hider RC. Structure-function investigation of the interaction of 1- and 2-substituted 3-hydroxypyridin-4-ones with 5-lipoxygenase and ribonucleotide reductase. The Journal of Biological Chemistry. 276: 48814-22. PMID 11602611 DOI: 10.1074/Jbc.M109551200  0.689
2001 Hider RC, Liu ZD, Khodr HH. Metal chelation of polyphenols Methods in Enzymology. 335: 190-203. PMID 11400368 DOI: 10.1016/S0076-6879(01)35243-6  0.542
2001 Liu ZD, Piyamongkol S, Liu DY, Khodr HH, Lu SL, Hider RC. Synthesis of 2-amido-3-hydroxypyridin-4(1H)-ones: Novel iron chelators with enhanced pFe3+ values Bioorganic and Medicinal Chemistry. 9: 563-573. PMID 11310590 DOI: 10.1016/S0968-0896(00)00273-X  0.694
2001 Liu ZD, Lockwood M, Rose S, Theobald AE, Hider RC. Structure-activity investigation of the inhibition of 3-hydroxypyridin-4-ones on mammalian tyrosine hydroxylase. Biochemical Pharmacology. 61: 285-90. PMID 11172732 DOI: 10.1016/S0006-2952(00)00551-7  0.643
2001 Liu ZD, Piyamongkol S, Hider RC. The design and properties of 3-hydroxypyridin-4-one iron chelators with high pFe(3+) values. Transfusion Science. 23: 269-70. PMID 11099914 DOI: 10.1016/S0955-3886(00)00106-5  0.669
2001 Rakba N, Gaboriau F, Loyer P, Pasdeloup NC, Hider R, Brissot P, Lescoat G. Iron mobilization, cytoprotection and inhibition of cell proliferation in normal and transformed rat hepatocyte cultures by the hydroxypyridinone CP411, compared to CP20 Journal of Hepatology. 34: 90-90. DOI: 10.1016/S0168-8278(01)81194-6  0.362
2001 Piyamongkol S, Liu ZD, Hider RC. Novel synthetic approach to 2-(1′-hydroxyalkyl)- and 2-amido-3-hydroxypyridin-4-ones Tetrahedron. 57: 3479-3486. DOI: 10.1016/S0040-4020(01)00222-8  0.649
2000 Von Wiren N, Khodr H, Hider RC. Hydroxylated phytosiderophore species possess an enhanced chelate stability and affinity for iron(III) Plant Physiology. 124: 1149-1157. PMID 11080292 DOI: 10.1104/Pp.124.3.1149  0.465
2000 Liu DY, Liu ZD, Lu SL, Hider RC. Hydrolytic and metabolic characteristics of the esters of 1-(3'-hydroxypropyl)-2-methyl-3-hydroxypyridin-4-one (CP41), potentially useful iron chelators. Pharmacology & Toxicology. 86: 228-33. PMID 10862505 DOI: 10.1034/J.1600-0773.2000.D01-40.X  0.626
2000 Liu ZD, Liu DY, Lu SL, Hider RC. Design, synthesis, and biological evaluation of aromatic ester prodrugs of 1-(3'-hydroxypropyl)-2-methyl-3-hydroxypyridin-4-one (CP41) as orally active iron chelators. Arzneimittel-Forschung. 50: 461-70. PMID 10858874 DOI: 10.1055/S-0031-1300231  0.634
2000 Loréal O, Gosriwatana I, Guyader D, Porter J, Brissot P, Hider RC. Determination of non-transferrin-bound iron in genetic hemochromatosis using a new HPLC-based method Journal of Hepatology. 32: 727-733. PMID 10845658 DOI: 10.1016/S0168-8278(00)80240-8  0.46
2000 Liu ZD, Khodr HH, Lu SL, Hider RC. Design, synthesis and evaluation of N-basic substituted 3-hydroxypyridin-4-ones: Orally active iron chelators with lysosomotrophic potential Journal of Pharmacy and Pharmacology. 52: 263-272. PMID 10757413 DOI: 10.1211/0022357001773940  0.682
2000 Dodoo ANO, Bansal S, Barlow DJ, Bennet FC, Hider RC, Lansley AB, Lawrence MJ, Marriott C. Systematic investigations of the influence of molecular structure on the transport of peptides across cultured alveolar cell monolayers Pharmaceutical Research. 17: 7-14. PMID 10714601 DOI: 10.1023/A:1007514121527  0.753
2000 Liu DY, Liu ZD, Lu SL, Hider RC. Liquid extraction and ion-pair HPLC for determination of hydrophilic 3-hydroxypyridin-4-one iron chelators. Journal of Pharmaceutical and Biomedical Analysis. 21: 759-65. PMID 10701941 DOI: 10.1016/S0731-7085(99)00211-3  0.604
2000 Valk Bd, Addicks MA, Gosriwatana I, Lu S, Hider R, Marx JJM. Non‐transferrin‐bound iron is present in serum of hereditary haemochromatosis heterozygotes European Journal of Clinical Investigation. 30: 248-251. PMID 10692002 DOI: 10.1046/J.1365-2362.2000.00628.X  0.395
2000 Dodoo AN, Bansal SS, Barlow DJ, Bennet F, Hider RC, Lansley AB, Lawrence MJ, Marriott C. Use of alveolar cell monolayers of varying electrical resistance to measure pulmonary peptide transport. Journal of Pharmaceutical Sciences. 89: 223-31. PMID 10688751 DOI: 10.1002/(Sici)1520-6017(200002)89:2<223::Aid-Jps9>3.0.Co;2-R  0.752
1999 Hider RC, Bittel D, Andrews GK. Competition between iron(III)-selective chelators and zinc-finger domains for zinc(II). Biochemical Pharmacology. 57: 1031-1035. PMID 10796073 DOI: 10.1016/S0006-2952(99)00014-3  0.414
1999 Liu ZD, Khodr HH, Liu DY, Lu SL, Hider RC. Synthesis, physicochemical characterization, and biological evaluation of 2-(1'-hydroxyalkyl-3-hydroxypyridin-4-ones: Novel iron chelators with enhanced pFe3+ values Journal of Medicinal Chemistry. 42: 4814-4823. PMID 10579844 DOI: 10.1021/Jm991080O  0.703
1999 Gosriwatana I, Loreal O, Lu S, Brissot P, Porter J, Hider RC. Quantification of non-transferrin-bound iron in the presence of unsaturated transferrin. Analytical Biochemistry. 273: 212-220. PMID 10469492 DOI: 10.1006/Abio.1999.4216  0.463
1999 Liu DY, Liu ZD, Lu SL, Hider RC. Gradient ion-pair high-performance liquid chromatographic method for analysis of 3-hydroxypyridin-4-one iron chelators. Journal of Chromatography. B, Biomedical Sciences and Applications. 730: 135-9. PMID 10437681 DOI: 10.1016/S0378-4347(99)00198-X  0.634
1999 Liu ZD, Liu DY, Lu SL, Hider RC. Synthesis, physicochemical properties and biological evaluation of aromatic ester prodrugs of 1-(2'-hydroxyethyl)-2-ethyl-3-hydroxypyridin-4-one (CP102): orally active iron chelators with clinical potential. The Journal of Pharmacy and Pharmacology. 51: 555-64. PMID 10411215 DOI: 10.1211/0022357991772655  0.665
1999 Bennett FA, Barlow DJ, Dodoo AN, Hider RC, Lansley AB, Lawrence MJ, Marriott C, Bansal SS. Synthesis and properties of (6,7-dimethoxy-4-coumaryl)alanine: a fluorescent peptide label. Analytical Biochemistry. 270: 15-23. PMID 10328760 DOI: 10.1006/Abio.1999.4081  0.763
1999 Habgood MD, Liu ZD, Dehkordi LS, Khodr HH, Abbott J, Hider RC. Investigation into the correlation between the structure of hydroxypyridinones and blood-brain barrier permeability Biochemical Pharmacology. 57: 1305-1310. PMID 10230774 DOI: 10.1016/S0006-2952(99)00031-3  0.636
1999 von Wiren N, Klair S, Bansal S, Briat JF, Khodr H, Shioiri T, Leigh RA, Hider RC. Nicotianamine chelates both FeIII and FeII. Implications for metal transport in plants Plant Physiology. 119: 1107-14. PMID 10069850 DOI: 10.1104/Pp.119.3.1107  0.308
1999 Liu ZD, Lu SL, Hider RC. In vivo iron mobilisation evaluation of hydroxypyridinones in 59Fe-ferritin-loaded rat model. Biochemical Pharmacology. 57: 559-66. PMID 9952320 DOI: 10.1016/S0006-2952(98)00319-0  0.638
1999 Rai BL, Liu ZD, Liu DY, Lu SL, Hider RC. Synthesis, physicochemical properties and biological evaluation of ester prodrugs of 3-hydroxypyridin-4-ones: design of orally active chelators with clinical potential European Journal of Medicinal Chemistry. 34: 475-485. DOI: 10.1016/S0223-5234(99)80097-X  0.625
1999 Rai BL, Khodr H, Hider RC. Synthesis, physico-chemical and iron(III)-chelating properties of novel hexadentate 3-hydroxy-2(1H)pyridinone ligands Tetrahedron. 55: 1129-1142. DOI: 10.1016/S0040-4020(98)01091-6  0.434
1998 Rai BL, Dekhordi LS, Khodr H, Jin Y, Liu Z, Hider RC. Synthesis, physicochemical properties, and evaluation of N-substituted- 2-alkyl-3-hydroxy-4(1H)-pyridinones Journal of Medicinal Chemistry. 41: 3347-3359. PMID 9719587 DOI: 10.1021/Jm9707784  0.489
1998 Kayyali R, Pannala AS, Khodr H, Hider RC. Comparative radical scavenging ability of bidentate iron(III) chelators Biochemical Pharmacology. 55: 1327-1332. PMID 9719489 DOI: 10.1016/S0006-2952(97)00602-3  0.413
1998 Kayyali RS, Porter JB, Hider RC. The design of low toxicity 3‐hydroxy‐pyridin‐4‐one iron chelators Journal of Pharmacy and Pharmacology. 50: 261-261. DOI: 10.1111/J.2042-7158.1998.Tb02461.X  0.444
1998 Liu DY, Gosriwatana I, Liu SL, Liu ZD, Hider RC. CE determination of the Fe (III) complex of 1‐(2′‐carboxyethyl)‐2‐methyl‐3‐hydroxypyridin‐4‐one (CP38) Journal of Pharmacy and Pharmacology. 50: 126-126. DOI: 10.1111/J.2042-7158.1998.Tb02326.X  0.301
1998 Hider RC. Management of iron overload in anaemia Journal of Pharmacy and Pharmacology. 50: 24-24. DOI: 10.1111/J.2042-7158.1998.Tb02224.X  0.403
1998 Zuberi S, Glen A, Hider RC, Bansal SS. Synthesis of asymmetric systines Tetrahedron Letters. 39: 7567-7570. DOI: 10.1016/S0040-4039(98)01614-1  0.728
1998 Duhme A-, Hider RC, Naldrett MJ, Pau RN. The stability of the molybdenum-azotochelin complex and its effect on siderophore production in Azotobacter vinelandii Journal of Biological Inorganic Chemistry. 3: 520-526. DOI: 10.1007/S007750050263  0.395
1997 Bradley SJ, Gosriwitana I, Srichairatanakool S, Hider RC, Porter JB. Non‐transferrin‐bound iron induced by myeloablative chemotherapy British Journal of Haematology. 99: 337-343. PMID 9375751 DOI: 10.1046/J.1365-2141.1997.4143221.X  0.339
1997 Zanninelli G, Choudury R, Loreal O, Guyader D, Lescoat G, Arnaud J, Verna R, Cosson B, Singh S, Hider RC, Brissot P. Novel orally active iron chelators (3-hydroxypyridin-4-ones) enhance the biliary excretion of plasma non-transferrin-bound iron in rats Journal of Hepatology. 27: 176-184. PMID 9252093 DOI: 10.1016/S0168-8278(97)80299-1  0.465
1997 Pattanapanyasat K, Thaithong S, Kyle DE, Udomsangpetch R, Yongvanitchit K, Hider RC, Webster HK. Flow cytometric assessment of hydroxypyridinone iron chelators on in vitro growth of drug-resistant malaria. Cytometry. 27: 84-91. PMID 9000589 DOI: 10.1002/(Sici)1097-0320(19970101)27:1<84::Aid-Cyto11>3.0.Co;2-O  0.427
1997 Smith AG, Clothier B, Francis JE, Gibbs AH, Matteis FD, Hider RC. Protoporphyria induced by the orally active iron chelator 1,2-diethyl-3-hydroxypyridin-4-one in C57BL/10ScSn mice. Blood. 89: 1045-1051. DOI: 10.1182/Blood.V89.3.1045  0.431
1997 Hider RC, Liu Z. The Treatment of Malaria with Iron Chelators Journal of Pharmacy and Pharmacology. 49: 59-64. DOI: 10.1111/J.2042-7158.1997.Tb06162.X  0.419
1997 Kayyali RS, Porter JB, Hider RC. Inhibition of iron-containing metalloenzymes by 3-hydroxypyridin-4-one chelators Journal of Inorganic Biochemistry. 67: 331. DOI: 10.1016/S0162-0134(97)80200-0  0.466
1997 Bennett FA, Barlow DJ, Dodoo ANO, Hider RC, Lansley AB, Lawrence MJ, Marriott C, Bansal SS. L-(6,7-dimethoxy-4-coumaryl) alanine: An intrinsic probe for the labelling of peptides Tetrahedron Letters. 38: 7449-7452. DOI: 10.1016/S0040-4039(97)01753-X  0.722
1997 Dubme A, Hider RC, Khodr HH. Synthesis and Iron‐Binding Properties of Protochelin, the Tris (catecholamide) Siderophore of Azotobacter vinelandii Chemische Berichte. 130: 969-973. DOI: 10.1002/Cber.19971300726  0.306
1996 Kime R, Gibson A, Yong W, Hider R, Powers H. Chromatographic method for the determination of non-transferrin-bound iron suitable for use on the plasma and bronchoalveolar lavage fluid of preterm babies Clinical Science. 91: 633-638. PMID 8942403 DOI: 10.1042/Cs0910633  0.397
1996 Cooper CE, Lynagh GR, Hoyes KP, Hider RC, Cammack R, Porter JB. The Relationship of Intracellular Iron Chelation to the Inhibition and Regeneration of Human Ribonucleotide Reductase Journal of Biological Chemistry. 271: 20291-20299. PMID 8702762 DOI: 10.1074/Jbc.271.34.20291  0.46
1996 Abeysinghe RD, Roberts PJ, Cooper CE, MacLean KH, Hider RC, Porter JB. The Environment of the Lipoxygenase Iron Binding Site Explored with Novel Hydroxypyridinone Iron Chelators Journal of Biological Chemistry. 271: 7965-7972. PMID 8626476 DOI: 10.1074/Jbc.271.14.7965  0.471
1996 Hider RC, Choudhury R, Rai BL, Dehkordi LS, Singh S. Design of Orally Active Iron Chelators Acta Haematologica. 95: 6-12. PMID 8604587 DOI: 10.1159/000203851  0.462
1996 Klair S, Hider RC, Adams MZ, Leigh RA. Studies of iron transport in wheat using synthetic phytosiderophores Journal of Plant Nutrition. 19: 1295-1307. DOI: 10.1080/01904169609365199  0.391
1996 Duhme AK, Hider RC, Khodr H. Spectrophotometric competition study between molybdate and Fe(III) hydroxide on N,N'-bis(2,3-dihydroxybenzoyl)-L-lysine, a naturally occurring siderophore synthesized by Azotobacter vinelandii Biometals. 9: 245-248. DOI: 10.1007/Bf00817923  0.398
1995 Singh S, Khodr H, Taylor MI, Hider RC. Therapeutic iron chelators and their potential side-effects Biochemical Society Symposium. 61: 127-137. PMID 8660390 DOI: 10.1042/Bss0610127  0.471
1995 Hider RC. Potential protection from toxicity by oral iron chelators. Toxicology Letters. 961-7. PMID 8597168 DOI: 10.1016/0378-4274(95)03606-7  0.471
1995 Ward RJ, Dexter D, Florence A, Aouad F, Hider R, Jenner P, Crichton RR. Brain iron in the ferrocene-loaded rat: Its chelation and influence on dopamine metabolism Biochemical Pharmacology. 49: 1821-1826. PMID 7598744 DOI: 10.1016/0006-2952(94)00521-M  0.509
1995 Xiao G, Helm Dvd, Hider RC, Dobbin PS. Crystal Structure and Conformational Studies of the Ferric Hexadentate N,N,N-Tris[2-(3-hydroxy-2-oxo-1,2-dihydropyridin-1-yl)acetamido]ethylamine Complex (FeCP130) as a Specific Iron(III) Chelator Inorganic Chemistry. 34: 1268-1270. DOI: 10.1021/Ic00109A038  0.341
1995 Klair S, Adams Z, Hider RC, Leigh RA. The role of phytosiderophores in iron uptake by cereal plants Journal of Inorganic Biochemistry. 59: 109. DOI: 10.1016/0162-0134(95)97219-G  0.383
1994 Maxton PG, Thompson RP, Hider RC. Absorption of iron from ferric hydroxypyranone complexes British Journal of Nutrition. 71: 203-207. PMID 8142332 DOI: 10.1079/Bjn19940127  0.359
1994 Epemolu RO, Ackerman R, Porter JB, Hider RC, Damani LA, Singh S. HPLC determination of 1,2-diethyl-3-hydroxypyridin-4-one (CP94), its iron complex [Fe(III) (CP94)3] and glucuronide conjugate [CP94-GLUC] in serum and urine of thalassaemic patients. Journal of Pharmaceutical and Biomedical Analysis. 12: 923-30. PMID 7981322 DOI: 10.1016/0731-7085(94)E0027-X  0.456
1994 Porter JB, Singh S, Hoyes KP, Epemolu O, Abeysinghe RD, Hider RC. Lessons from Preclinical and Clinical Studies with 1,2-Diethyl-3-Hydroxypyridin-4-One, CP94 and Related Compounds Advances in Experimental Medicine and Biology. 356: 361-370. PMID 7887242 DOI: 10.1007/978-1-4615-2554-7_38  0.474
1994 Hider RC, Epemolu O, Singh S, Porter JB. Iron chelator design. Advances in Experimental Medicine and Biology. 356: 343-349. PMID 7887240 DOI: 10.1007/978-1-4615-2554-7_36  0.443
1994 Hider RC. Overview Anti-infectives: The treatment of malaria with iron chelators Expert Opinion On Therapeutic Patents. 4: 931-940. DOI: 10.1517/13543776.4.8.931  0.376
1994 Chana SS, Hider RC. A Novel Macrobicyclic Cryptand Incorporating 3 Endocyclic Hydroxamate Donor Groups Tetrahedron Letters. 35: 9455-9458. DOI: 10.1016/S0040-4039(00)78569-8  0.416
1993 Dobbin PS, Hider RC, Hall AD, Taylor PD, Sarpong P, Porter JB, Xiao G, van der Helm D. Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: orally active iron chelators with clinical potential. Journal of Medicinal Chemistry. 36: 2448-58. PMID 8355246 DOI: 10.1021/Jm00069A002  0.475
1993 Lamb DJ, Hider RC, Leake DS. Hydroxypyridinones and desferrioxamine inhibit macrophage-mediated LDL oxidation by iron but not by copper. Biochemical Society Transactions. 21: 234S. PMID 8224391 DOI: 10.1042/Bst021234S  0.398
1992 Singh S, Mohammed N, Ackerman R, Porter JB, Hider RC. Quantification of desferrioxamine and its iron chelating metabolites by high-performance liquid chromatography and simultaneous ultraviolet-visible/radioactive detection. Analytical Biochemistry. 203: 116-20. PMID 1524206 DOI: 10.1016/0003-2697(92)90050-H  0.437
1992 Hershko C, Gordeuk VR, Brittenham GM, Thuma PE, Theanacho EN, Spira DT, Hider RC, Peto TEA. The antimalarial effect of iron chelators: Studies in animal models and in humans with mild falciparum malaria Journal of Inorganic Biochemistry. 47: 267-277. PMID 1431886 DOI: 10.1016/0162-0134(92)84072-U  0.476
1992 Pattanapanyasat K, Webster HK, Tongtawe P, Kongcharoen P, Hider RC. Effect of orally active hydroxypyridinone iron chelators on human lymphocyte function. British Journal of Haematology. 82: 13-9. PMID 1419787 DOI: 10.1111/J.1365-2141.1992.Tb04587.X  0.391
1992 Hider RC, Singh S, Porter JB. Iron chelating agents with clinical potential Proceedings of the Royal Society B: Biological Sciences. 99: 137-168. DOI: 10.1017/S0269727000013117  0.425
1991 Perkins TD, Hider RC, Barlow DJ. Proposed solution structure of endothelin. International Journal of Peptide and Protein Research. 36: 128-33. PMID 2272749 DOI: 10.1111/J.1399-3011.1990.Tb00955.X  0.466
1991 Kelsey SM, Hider RC, Bloor JR, Blake DR, Gutterridge CN, Newland AC. Absorption of low and therapeutic doses of ferric maltol, a novel ferric iron compound, in iron deficient subjects using a single dose iron absorption test Journal of Clinical Pharmacy and Therapeutics. 16: 117-122. PMID 1856249 DOI: 10.1111/J.1365-2710.1991.Tb00292.X  0.449
1991 Hider RC, Hall AD. Clinically useful chelators of tripositive elements. Progress in Medicinal Chemistry. 28: 41-173. PMID 1843549 DOI: 10.1016/S0079-6468(08)70363-1  0.406
1991 Stefanini S, Chiancone E, Cavallo S, Saez V, Hall AD, Hider RC. The interaction of hydroxypyridinones with human serum transferrin and ovotransferrin. Journal of Inorganic Biochemistry. 44: 27-37. PMID 1791467 DOI: 10.1016/0162-0134(91)80058-P  0.452
1991 Barrand MA, Callingham BA, Dobbin P, Hider RC. Dissociation of a ferric maltol complex and its subsequent metabolism during absorption across the small intestine of the rat. British Journal of Pharmacology. 102: 723-729. PMID 1364845 DOI: 10.1111/J.1476-5381.1991.Tb12240.X  0.416
1991 Porter J, Hoyes K, Abeysinghe R, Brooks P, Huehns E, Hider R. Comparison of the subacute toxicity and efficacy of 3-hydroxypyridin-4-one iron chelators in overloaded and nonoverloaded mice. Blood. 78: 2727-2734. DOI: 10.1182/Blood.V78.10.2727.Bloodjournal78102727  0.456
1990 Singh S, Hider RC, Porter JB. A direct method for quantification of non-transferrin-bound iron Analytical Biochemistry. 186: 320-323. PMID 2363505 DOI: 10.1016/0003-2697(90)90088-Q  0.478
1990 Streater M, Taylor PD, Hider RC, Porter J. Novel 3-hydroxy-2(1H)-pyridinones. Synthesis, iron(III)-chelating properties and biological activity Journal of Medicinal Chemistry. 33: 1749-1755. PMID 2342069 DOI: 10.1021/Jm00168A033  0.483
1990 Hider RC, Ejim L, Taylor PD, Gale R, Huehns E, Porter JB. Facilitated uptake of zinc into human erythrocytes. Relevance to the treatment of sickle-cell anaemia. Biochemical Pharmacology. 39: 1005-1012. PMID 2322289 DOI: 10.1016/0006-2952(90)90278-S  0.32
1990 Hershko C, Link G, Pinson A, Avramovici-Grisaru S, Sarel S, Peter HH, Hider RC, Grady RW. New Orally Effective Iron Chelators Annals of the New York Academy of Sciences. 612: 351-360. PMID 2291563 DOI: 10.1111/J.1749-6632.1990.Tb24322.X  0.441
1990 Hider RC, Singh S, Porter JB, Huehns ER. The development of hydroxypyridin-4-ones as orally active iron chelators. Annals of the New York Academy of Sciences. 612: 327-338. PMID 2291561 DOI: 10.1111/J.1749-6632.1990.Tb24320.X  0.444
1990 Singh S, Hider RC, Porter JB. Separation and identification of desferrioxamine and its iron chelating metabolites by high-performance liquid chromatography and fast atom bombardment mass spectrometry: Choice of complexing agent and application to biological fluids Analytical Biochemistry. 187: 212-219. PMID 2116739 DOI: 10.1016/0003-2697(90)90446-G  0.429
1990 Greene RJ, Hall AD, Hider RC. The interaction of orally administered iron with levodopa and methyldopa therapy. The Journal of Pharmacy and Pharmacology. 42: 502-4. PMID 1980293 DOI: 10.1111/J.2042-7158.1990.Tb06605.X  0.42
1990 Porter J, Morgan J, Hoyes K, Burke L, Huehns E, Hider R. Relative oral efficacy and acute toxicity of hydroxypyridin-4-one iron chelators in mice. Blood. 76: 2389-2396. DOI: 10.1182/Blood.V76.11.2389.2389  0.401
1990 Epemolu RO, Singh S, Hider RC, Damani LA. Chromatography of 3-hydroxypyridin-4-ones: novel orally active iron chelators Journal of Chromatography A. 519: 171-178. DOI: 10.1016/0021-9673(90)85145-L  0.369
1989 Ford S, Cooper RA, Evans RW, Hider RC, Williams PH. Domain preference in iron removal from human transferrin by the bacterial siderophores aerobactin and enterochelin. European Journal of Biochemistry. 178: 477-81. PMID 2974803 DOI: 10.1111/J.1432-1033.1988.Tb14473.X  0.452
1989 Pall H, Blake DR, Winyard P, Lunec J, Williams A, Good PA, Kritzinger EE, Cornish A, Hider RC. Ocular toxicity of desferrioxamine--an example of copper promoted auto-oxidative damage? British Journal of Ophthalmology. 73: 42-47. PMID 2784062 DOI: 10.1136/Bjo.73.1.42  0.37
1989 Brady MC, Lilley KS, Treffry A, Harrison PM, Hider RC, Taylor PD. Release of iron from ferritin molecules and their iron-cores by 3-hydroxypyridinone chelators in vitro. Journal of Inorganic Biochemistry. 35: 9-22. PMID 2709002 DOI: 10.1016/0162-0134(89)84002-4  0.472
1989 Kelsey SM, Blake DR, Hider RC, Gutteridge CN, Newland AC. Absorption of ferric maltol, a novel ferric iron compound, in iron-deficient subjects Clinical and Laboratory Haematology. 11: 287-288. PMID 2591161 DOI: 10.1111/J.1365-2257.1989.Tb00222.X  0.457
1989 Porter JB, Hoyes KP, Abeysinghe R, Huehns ER, Hider RC. Animal toxicology of iron chelator L1. The Lancet. 334: 156. PMID 2567914 DOI: 10.1016/S0140-6736(89)90206-7  0.404
1989 Hider RC, Lerch K. The inhibition of tyrosinase by pyridinones. Biochemical Journal. 257: 289-290. PMID 2493243 DOI: 10.1042/Bj2570289  0.457
1989 Singh S, Hider RC, Porter JB. Quantification of non-transferrin-bound iron in thalassaemic plasma Biochemical Society Transactions. 17: 697-698. DOI: 10.1042/Bst0170697  0.401
1989 Deighton N, Hider RC. Intracellular low molecular weight iron Biochemical Society Transactions. 17: 490-490. DOI: 10.1042/Bst0170490  0.434
1988 Singh S, Hider RC. Colorimetric detection of the hydroxyl radical: comparison of the hydroxyl-radical-generating ability of various iron complexes. Analytical Biochemistry. 171: 47-54. PMID 3407920 DOI: 10.1016/0003-2697(88)90123-6  0.442
1988 Levey JA, Barrand MA, Callingham BA, Hider RC. Characteristics of iron(III) uptake by isolated fragments of rat small intestine in the presence of the hydroxypyrones, maltol and ethyl maltol. Biochemical Pharmacology. 37: 2051-2057. PMID 3377810 DOI: 10.1016/0006-2952(88)90556-4  0.48
1988 Winyard PG, Hider RC, Lunec J, Drake AF, Blake DR. Role of oxidative modification in the lability of ceruloplasmin. Basic Life Sciences. 49: 341-345. PMID 3250490 DOI: 10.1007/978-1-4684-5568-7_51  0.327
1988 Huehns ER, Porter JB, Hider RC. Selection of hydroxypyridin-4-ones for the treatment of iron overload using in vitro and in vivo models. Hemoglobin. 12: 593-600. PMID 3209401 DOI: 10.3109/03630268808991649  0.486
1987 Gyparaki M, Porter JB, Hirani S, Streater M, Hider RC, Huehns ER. In vivo evaluation of hydroxypyridone iron chelators in a mouse model. Acta Haematologica. 78: 217-221. PMID 3120475 DOI: 10.1159/000205878  0.397
1987 Barrand MA, Callingham BA, Hider RC. Effects of the pyrones, maltol and ethyl maltol, on iron absorption from the rat small intestine Journal of Pharmacy and Pharmacology. 39: 203-211. PMID 2883285 DOI: 10.1111/J.2042-7158.1987.Tb06249.X  0.459
1986 Gyparaki M, Porter JB, Huehns ER, Hider RC. Evaluation in vivo of hydroxypyrid-4-one iron chelators intended for the treatment of iron overload by the oral route Biochemical Society Transactions. 14: 1181-1181. DOI: 10.1042/Bst0141181  0.459
1986 Porter JB, Gyparaki M, Huehns ER, Hider RC. The relationship between lipophilicity of hydroxypyrid-4-one iron chelators and cellular iron mobilization, using an hepatocyte culture model Biochemical Society Transactions. 14: 1180-1180. DOI: 10.1042/Bst0141180  0.477
1985 Blake DR, Winyard P, Lunec J, Williams A, Good PA, Crewes SJ, Gutteridge JMC, Rowley D, Halliwell B, Cornish A, Hider RC. Cerebral and ocular toxicity induced by desferrioxamine. Qjm: An International Journal of Medicine. 56: 345-355. DOI: 10.1093/Oxfordjournals.Qjmed.A067880  0.423
1985 Hider R, Bickar D, Morrison I, Silver J. Additions and Corrections - Siderophore Iron-Release Mechanisms Journal of the American Chemical Society. 107: 2199-2199. DOI: 10.1021/Ja00293A602  0.404
1984 Hider RC, Bickar D, Morrison IEG, Silver J. Siderophore iron-release mechanisms Journal of the American Chemical Society. 106: 6983-6987. DOI: 10.1021/Ja00335A020  0.399
1983 Tahir S, Hider RC. An affinity ligand for phospholipase A2 purification. Analytical Biochemistry. 135: 332-334. PMID 6660509 DOI: 10.1016/0003-2697(83)90691-7  0.302
1983 Hider RC, Howlin B, Miller JR, Mohd-Nor AR, Silver J. Model compounds for microbial iron-transport compounds. Part IV. Further solution chemistry and Mössbauer studies on iron(II) and iron(III) catechol complexes Inorganica Chimica Acta. 80: 51-56. DOI: 10.1016/S0020-1693(00)91261-1  0.474
1982 Howlin B, Hider RC, Silver J. Model compounds for microbial iron-transport compounds. Part 3. Solution chemistry and Mössbauer study of iron(II) and iron(III) complexes from 2,3-dihydroxypyridine and 2-mercapto-3-pyridinol Journal of the Chemical Society-Dalton Transactions. 1433-1438. DOI: 10.1039/Dt9820001433  0.461
1982 Hider RC, Mohd-Nor AR, Silver J, Neilands JB. Coordination of calcium by iron enterobactin Journal of Inorganic Biochemistry. 17: 205-213. DOI: 10.1016/S0162-0134(00)80099-9  0.431
1982 Hamed MY, Hider RC, Silver J. The Competition between Enterobactin and Glutathione for Iron Inorganica Chimica Acta. 66: 13-18. DOI: 10.1016/S0020-1693(00)85783-7  0.487
1982 Howlin B, Hider RC, Silver J. Model Compounds For Microbial Iron-Transport Compounds. Part 3. Solution Chemistry And Moessbauer Study Of Iron(Ii) And Iron(Iii) Complexes From 2,3-Dihydroxypyridine And 2-Mercapto-3-Pyridinol Cheminform. 13. DOI: 10.1002/Chin.198247068  0.458
1981 Hider RC, Mohd-Nor AR, Silver J, Morrison IEG, Rees LVC. Model compounds for microbial iron-transport compounds. Part 1. Solution chemistry and Mössbauer study of iron(II) and iron(III) complexes from phenolic and catecholic systems Journal of the Chemical Society-Dalton Transactions. 609-622. DOI: 10.1039/Dt9810000609  0.447
1981 Hider RC, Mohd-Nor AR, Silver J, Morrison IEG, Rees LVC. Model Compounds For Microbial Iron-Transport Compounds. Part 1. Solution Chemistry And Moessbauer Study Of Iron(Ii) And Iron(Iii) Complexes From Phenolic And Catecholic Systems Cheminform. 12. DOI: 10.1002/Chin.198120301  0.455
Show low-probability matches.