Aaron Bart - Publications

Affiliations: 
Biophysics Program University of Michigan, Ann Arbor, Ann Arbor, MI 

10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Petrunak EM, Bart AG, Peng HM, Auchus RJ, Scott EE. Human Cytochrome P450 17A1 Structures with Metabolites of Prostate Cancer Drug Abiraterone Reveal Substrate-Binding Plasticity and a Second Binding Site. The Journal of Biological Chemistry. 102999. PMID 36773804 DOI: 10.1016/j.jbc.2023.102999  0.751
2021 Bart AG, Morais G, Vangala VR, Loadman PM, Pors K, Scott EE. . Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 34607808 DOI: 10.1124/dmd.121.000642  0.759
2021 Vogt CD, Bart AG, Yadav R, Scott EE, Aubé J. Effects of fluorine substitution on substrate conversion by cytochromes P450 17A1 and 21A2. Organic & Biomolecular Chemistry. 19: 7664-7669. PMID 34524336 DOI: 10.1039/d1ob01178b  0.755
2020 Lu J, Bart AG, Wu Q, Criscione KR, McLeish MJ, Scott EE, Grunewald GL. Structure-Based Drug Design of Bisubstrate Inhibitors of Phenylethanolamine -Methyltransferase Possessing Low Nanomolar Affinity at Both Substrate Binding Domains. Journal of Medicinal Chemistry. PMID 33147410 DOI: 10.1021/acs.jmedchem.0c01475  0.694
2020 Russell LE, Schleiff MA, Gonzalez E, Bart AG, Broccatelli F, Hartman JH, Humphreys WG, Lauschke VM, Martin I, Nwabufo C, Prasad B, Scott EE, Segall M, Takahashi R, Taub ME, et al. Advances in the study of drug metabolism - symposium report of the 12th Meeting of the International Society for the Study of Xenobiotics (ISSX). Drug Metabolism Reviews. 1-13. PMID 32456484 DOI: 10.1080/03602532.2020.1765793  0.625
2020 Bart AG, Harris KL, Gillam EMJ, Scott EE. Structure of an ancestral mammalian family 1B1 cytochrome P450 with increased thermostability. The Journal of Biological Chemistry. PMID 32156703 DOI: 10.1074/Jbc.Ra119.010727  0.768
2019 Bart AG, Takahashi RH, Wang X, Scott EE. Human Cytochrome P450 1A1 Adapts Active Site for Atypical Nonplanar Substrate. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 31757797 DOI: 10.1124/Dmd.119.089607  0.745
2018 Bart AG, Scott EE. Structures of human cytochrome P450 1A1 with bergamottin and erlotinib reveal active-site modifications for binding of diverse ligands. The Journal of Biological Chemistry. PMID 30254074 DOI: 10.1074/Jbc.Ra118.005588  0.76
2017 Bart AG, Scott EE. Structural and Functional Effects of Cytochrome b5 Interactions with Human Cytochrome P450 Enzymes. The Journal of Biological Chemistry. PMID 29079577 DOI: 10.1074/Jbc.Ra117.000220  0.688
2012 DeVore NM, Meneely KM, Bart AG, Stephens ES, Battaile KP, Scott EE. Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine. The Febs Journal. 279: 1621-31. PMID 22051186 DOI: 10.1111/J.1742-4658.2011.08412.X  0.469
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